C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 CHEMBL138173 IC50 0.04 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)OC1C2CC3CC(C2)CC1C3 CHEMBL2282783 IC50 0.04 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL137733 IC50 0.07 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC12CC3CC(CC(C3)C1)C2 CHEMBL2282782 IC50 0.07 nM
CC(C)CC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL420020 Ki app 0.08 nM
CC(C)CC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282766 IC50 0.08 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL308258 IC50 0.09 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL24088 IC50 0.09 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL2282775 IC50 0.09 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL2282776 IC50 0.09 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(Cl)c3)CCC12 CHEMBL108625 IC50 0.1 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(C(F)(F)F)c3)CCC12 CHEMBL432439 IC50 0.1 nM
Cc1ccc(NC(=O)C2CCC3C4CCC5NC(=O)C=C[C@]5(C)C4CC[C@]23C)cc1 CHEMBL322592 IC50 0.1 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)Nc3c(C(F)(F)F)cccc3C(F)(F)F)[C@@]2(C)CCC1=O CHEMBL445627 IC50 0.1 nM
CC(C)CC(=O)[C@H]1CCC2C3CN(C)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL80160 IC50 0.1 nM
CC(C)CC(=O)[C@H]1CC[C@H]2[C@@H]3CN(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282649 IC50 0.1 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1 CHEMBL412425 IC50 0.12 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1 CHEMBL2282773 IC50 0.12 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N(Cc1ccccc1)Cc1ccccc1 CHEMBL436215 IC50 0.13 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)N(Cc1ccccc1)Cc1ccccc1 CHEMBL2282777 IC50 0.13 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL306722 IC50 0.16 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC(c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL2282774 IC50 0.16 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL710 IC50 0.18 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL138225 IC50 0.18 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC1(c2ccc(Cl)cc2)CCCC1 CHEMBL420415 IC50 0.18 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cccc2ccccc12 CHEMBL285599 IC50 0.2 nM
CN(C(=O)[C@H]1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@@]21C)c1ccccc1 CHEMBL25072 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccccc3)CCC12 CHEMBL324210 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc4ccccc4c3)CCC12 CHEMBL107719 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(F)cc3)CCC12 CHEMBL321617 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(F)c3)CCC12 CHEMBL323788 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc4ccccc34)CCC12 CHEMBL107654 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(Cl)cc3)CCC12 CHEMBL109170 IC50 0.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3cccc(Br)c3)CCC12 CHEMBL110398 IC50 0.2 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL89240 IC50 0.2 nM
CC(C)(C)c1ccccc1NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL88494 IC50 0.2 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(c2ccccc2)c2ccccc2)[C@@]2(C)CCC(=O)C=C12 CHEMBL306554 IC50 0.2 nM
CN1C[C@H]2[C@@H]3CC[C@H](C(=O)NC(c4ccccc4)c4ccccc4)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 CHEMBL2282644 IC50 0.2 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL2282763 IC50 0.2 nM
CC(C)(C)c1ccccc1NC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282765 IC50 0.2 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NN(c1ccccc1)c1ccccc1 CHEMBL312531 IC50 0.23 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2298601 IC50 0.23 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NN(c1ccccc1)c1ccccc1 CHEMBL2282771 IC50 0.23 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1c(Cl)cccc1C(F)(F)F CHEMBL86832 IC50 0.27 nM
Cc1cccc(NC(=O)C2CCC3C4CCC5NC(=O)C=C[C@]5(C)C4CC[C@]23C)c1 CHEMBL108151 IC50 0.3 nM
CCCC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL311577 IC50 0.3 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@]2(C)C=CC(=O)C=C12 CHEMBL308107 IC50 0.3 nM
CCCC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282640 IC50 0.3 nM
CN1C[C@H]2[C@@H]3CC[C@H](C(=O)NC4C5CC6CC(C5)CC4C6)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 CHEMBL2282647 IC50 0.3 nM
CC(C)N(C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL137691 IC50 0.36 nM
CC(C)N(C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C CHEMBL2282781 IC50 0.36 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)n1ccc2ccccc21 CHEMBL24465 IC50 0.4 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(C(F)(F)F)cc3)CCC12 CHEMBL323033 IC50 0.4 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)n3ccc4ccccc43)CCC12 CHEMBL321867 IC50 0.4 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CCc4cc(C(=O)O)ccc4[C@H]3CC[C@]12C CHEMBL1627951 Ki app 0.4 nM
CC1=C2N(C)CC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC34CC5CC(CC(C5)C3)C4)[C@@]2(C)CCC1=O CHEMBL307398 IC50 0.4 nM
CC(C)CC(=O)[C@H]1CCC2C3CNC4=C(Br)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL311045 IC50 0.4 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NC(C1CCCCC1)C1CCCCC1 CHEMBL77328 IC50 0.4 nM
CC1=C2N(C)C[C@H]3[C@@H]4CC[C@H](C(=O)NC5C6CC7CC(C6)CC5C7)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O CHEMBL2282645 IC50 0.4 nM
CC(C)CC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=C(Br)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282648 IC50 0.4 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NC(C1CCCCC1)C1CCCCC1 CHEMBL2282772 IC50 0.4 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)ccc1C(F)(F)F CHEMBL283245 IC50 0.5 nM
CC(C)(C)c1ccc(-c2ccc(C(F)(F)F)cc2NC(=O)[C@H]2CCC3C4CNC5=CC(=O)CC[C@]5(C)C4CC[C@@]32C)cc1 CHEMBL314069 IC50 0.5 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N1CCCCC1 CHEMBL77129 IC50 0.5 nM
CC(C)c1cc(C(C)C)c(C(=O)[C@H]2CCC3C4CNC5=CC(=O)CC[C@]5(C)C4CC[C@@]32C)c(C(C)C)c1 CHEMBL77124 IC50 0.5 nM
CC(C)c1cc(C(C)C)c(C(=O)[C@H]2CC[C@H]3[C@@H]4CNC5=CC(=O)CC[C@]5(C)[C@H]4CC[C@]23C)c(C(C)C)c1 CHEMBL2282639 IC50 0.5 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)N1CCCCC1 CHEMBL2282642 IC50 0.5 nM
CC(C)(C)c1ccc(-c2ccc(C(F)(F)F)cc2NC(=O)[C@H]2CC[C@H]3[C@@H]4CNC5=CC(=O)CC[C@]5(C)[C@H]4CC[C@]23C)cc1 CHEMBL2282764 IC50 0.5 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)NCc1ccccc1 CHEMBL135780 IC50 0.58 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)NCc1ccccc1 CHEMBL2282778 IC50 0.58 nM
CC(C)(C)N(O)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL78064 IC50 0.6 nM
CC(C)(C)N(O)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282641 IC50 0.6 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C(P(O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL78060 Ki app 0.8 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76192 IC50 0.88 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282655 IC50 0.88 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CC=C4C=C([PH](=O)O)CC[C@]4(C)C3CC[C@@]21C CHEMBL143220 Ki app 1.3 nM
CCCN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(c2ccccc2)c2ccccc2)[C@@]2(C)C=CC(=O)C=C12 CHEMBL309585 IC50 1.3 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N1CCSCC1 CHEMBL73816 IC50 1.3 nM
CCCN1C[C@H]2[C@@H]3CC[C@H](C(=O)NC(c4ccccc4)c4ccccc4)[C@@]3(C)CC[C@@H]2[C@@]2(C)C=CC(=O)C=C12 CHEMBL2282643 IC50 1.3 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)N1CCSCC1 CHEMBL2282768 IC50 1.3 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)Nc1ccccc1 CHEMBL280155 IC50 1.4 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)N3CCCc4ccccc43)CCC12 CHEMBL327098 IC50 1.4 nM
CC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC(C)(C)C)[C@@]2(C)CCC1=O CHEMBL78275 IC50 1.4 nM
CC1=C2NC[C@H]3[C@@H]4CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O CHEMBL2282651 IC50 1.4 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)Nc1ccccc1 CHEMBL2282767 IC50 1.4 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76648 IC50 1.5 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282760 IC50 1.5 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(C(=O)c4ccccc4)cc3)CCC12 CHEMBL110058 IC50 1.6 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(C)(C)C)[C@@]2(C)CCC(=O)C=C12 CHEMBL312143 IC50 1.7 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@]2(C)CCC(=O)C(Br)=C12 CHEMBL76260 IC50 1.7 nM
CN1C[C@H]2[C@@H]3CC[C@H](C(=O)NC4C5CC6CC(C5)CC4C6)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C(Br)=C12 CHEMBL2282646 IC50 1.7 nM
CN1C[C@H]2[C@@H]3CC[C@H](C(=O)NC(C)(C)C)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 CHEMBL2282653 IC50 1.7 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN=C4C=C(O)C5CC5[C@]4(C)C3CC[C@@]21C CHEMBL76693 IC50 1.8 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CNC4=CC(=O)C=C[C@]4(C)C3CC[C@@]21C CHEMBL3706586 IC50 1.8 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL1762030 IC50 1.8 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282762 IC50 1.8 nM
C[C@]12C=CC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)NC(c3ccccc3)(C(F)(F)F)C(F)(F)F)CC[C@@H]12 CHEMBL4569322 IC50 1.8 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(Cl)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL432729 IC50 1.9 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=C(Cl)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282660 IC50 1.9 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(Br)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL307181 IC50 2.1 nM
CC(C)N(C(=O)[C@H]1CC[C@H]2[C@@H]3CCc4cc(C(=O)O)ccc4[C@H]3CC[C@]12C)C(C)C CHEMBL1627395 IC50 2.1 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=C(Br)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282659 IC50 2.1 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2C3=C(CC[C@]12C)N1CCC(=O)C=C1CC3 CHEMBL1201841 IC50 2.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)Nc3ccc(-c4ccccc4)cc3)CCC12 CHEMBL109089 IC50 2.2 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76892 IC50 2.3 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL1762032 IC50 2.3 nM
C[C@]12CC[C@H]3[C@@H](CCC4CC(=O)C=CN43)[C@@H]1CCC2=O CHEMBL14220 IC50 2.4 nM
CON(C)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL307626 IC50 2.4 nM
CON(C)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282784 IC50 2.4 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CCN43)[C@@H]1CC[C@@H]2O CHEMBL269632 IC50 2.7 nM
CCN(C)C(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL136863 IC50 2.8 nM
CCN(C)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282780 IC50 2.8 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(C#N)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL25196 IC50 2.9 nM
C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CCN43)[C@@H]1CCC2=O CHEMBL14575 IC50 2.9 nM
C[C@]12CC=C3[C@@H](CCC4=CC(=O)CCN43)C1CC[C@@H]2O CHEMBL1237294 IC50 3.0 nM
COC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL297524 IC50 3.2 nM
COC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282785 IC50 3.2 nM
C[C@]12CC[C@H](OC(=O)C3CC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(Cl)=C(C=O)C[C@@H]12 CHEMBL3342891 IC50 3.2 nM
CC(NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C)(c1ccccc1)C(F)(F)F CHEMBL4540042 IC50 3.3 nM
C[C@]12CC=C3[C@@H](CCC4=CC(=O)CCN43)C1CCC2=O CHEMBL1237306 IC50 3.4 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=CC(=O)C(C)C[C@]4(C)C3CC[C@@]21C CHEMBL75982 IC50 3.4 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)C(C)(C)C[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282666 IC50 3.4 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CCN43)[C@@H]1CCC2=O CHEMBL274238 IC50 3.5 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(CC)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL308532 IC50 3.5 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=CC(=O)C=C[C@]4(C)C3CC[C@@]21C CHEMBL3706583 IC50 3.5 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(CC)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282665 IC50 3.5 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282761 IC50 3.5 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4N(C(=O)c4ccccc4)c4ccccc4)C3CC[C@@H]12 CHEMBL276320 IC50 3.75 nM
C[C@]12CCC3=C(CCC4=C3C(=O)CCN4)[C@@H]1CCC2=O CHEMBL1237307 IC50 3.8 nM
CCN(CC)C(=O)[C@H]1CCC2C3CCNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL78161 IC50 3.8 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL77765 IC50 3.9 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=C(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL1762031 IC50 3.9 nM
CC(C)Cc1ccc([C@H](C)Oc2ccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)cc2)cc1 CHEMBL25193 IC50 4.0 nM
CCCN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)N(CC)CC)[C@@]2(C)CCC(=O)C=C12 CHEMBL80163 IC50 4.2 nM
CCCN1C[C@H]2[C@@H]3CC[C@H](C(=O)N(CC)CC)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 CHEMBL1762035 IC50 4.2 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CN=C4C=C(O)C5CC5[C@]4(C)C3CC[C@@]21C CHEMBL311874 IC50 4.4 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282654 IC50 4.4 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C)C4=C(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL77144 IC50 4.5 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C)C4=C(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282656 IC50 4.5 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C(C)C)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76536 IC50 4.9 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C(C)C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282664 IC50 4.9 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C)C4=CC(=O)C5CC5[C@]4(C)C3CC[C@@]21C CHEMBL80669 IC50 5.0 nM
O=C(O)c1ccc(C(=O)c2ccc(Oc3ccccc3)cc2)cc1 CHEMBL36392 Ki app 5.0 nM
O=C(O)Cc1ccc(C(=O)c2ccc(Oc3ccc(Br)cc3)cc2)cc1 CHEMBL201138 IC50 5.0 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282661 IC50 5.0 nM
CCC[C@H]1C=C2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL125209 IC50 5.4 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CCN4[C@H]3CC[C@]12C CHEMBL276871 IC50 5.5 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C)C4=CC(=O)C=C[C@]4(C)C3CC[C@@]21C CHEMBL309261 IC50 5.7 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C)C4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282662 IC50 5.7 nM
O=C(O)Cc1ccc(C=C2CCN(C(=O)C(C3CCCCC3)C3CCCCC3)CC2)cc1 CHEMBL113726 IC50 6.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(I)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76803 IC50 6.0 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=C(I)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282658 IC50 6.0 nM
C=CC(=O)/C=C1/CCC2=C(CC[C@]3(C)C(=O)CC[C@@H]23)N1 CHEMBL1794821 IC50 6.1 nM
CN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)NC(C)(C)C)[C@@]2(C)C=CC(=O)C=C12 CHEMBL306507 IC50 6.7 nM
CC(C)NC(=O)[C@H]1CCC2C3CNC4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL135313 IC50 6.7 nM
CN1C[C@H]2[C@@H]3CC[C@H](C(=O)NC(C)(C)C)[C@@]3(C)CC[C@@H]2[C@@]2(C)C=CC(=O)C=C12 CHEMBL2282652 IC50 6.7 nM
CC(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282779 IC50 6.7 nM
O=C(O)Cc1ccc(C=C2CCN(C(=O)C(C3CCCCC3)C3CCCCC3)CC2)c(F)c1 CHEMBL115438 IC50 7.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL278283 Ki app 7.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C(C(=O)O)CC[C@]4(C)C3C=C[C@@]21C)C(C)C CHEMBL426217 Ki app 7.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3C=CC4=CC(C(=O)O)=CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL278167 Ki app 7.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N1CCOCC1 CHEMBL24291 IC50 7.1 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)N1CCOCC1 CHEMBL2282769 IC50 7.1 nM
CCN(C(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C)c1ccccc1 CHEMBL321923 IC50 7.9 nM
C[C@]12CC[C@H](OC(=O)C3CCCCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(Cl)=C(C=O)C[C@@H]12 CHEMBL3342894 IC50 8.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(C)C(=O)C=C[C@]4(C)C3CC[C@@]21C CHEMBL3706585 IC50 8.1 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CNC4=C(C)C(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282657 IC50 8.1 nM
CC1=C2N(C)CC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)NC(C)(C)C)[C@@]2(C)CCC1=O CHEMBL75320 IC50 8.6 nM
CC1=C2N(C)C[C@H]3[C@@H]4CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@@H]3[C@@]2(C)CCC1=O CHEMBL2282650 IC50 8.6 nM
CC(C)N(C(=O)COc1c(F)cc(-c2ccc(C(=O)O)cc2)cc1[N+](=O)[O-])C(C)C CHEMBL50113 IC50 9.8 nM
Cc1ccc(C(=O)c2ccc(C(=O)c3ccc(C(=O)O)cc3)cc2)cc1 CHEMBL25093 Ki 10.0 nM
CCCc1ccc(OC(C)c2ccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)cc2)cc1 CHEMBL279745 IC50 10.0 nM
O=C(O)c1cc2c(OCc3ccccc3)cccc2[nH]1 CHEMBL23399 Ki app 10.0 nM
COc1cc2cc(C(=O)O)n(C)c2cc1OCc1ccccc1 CHEMBL36772 Ki app 10.0 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)N3CCCCc4ccccc43)CCC12 CHEMBL326439 IC50 10.2 nM
CC(C)Cc1ccc(C(Nc2cccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)c2)c2ccc(CC(C)C)cc2)cc1 CHEMBL25083 IC50 11.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)C(C3CCCCC3)C3CCCCC3)CC2)c(F)c1 CHEMBL117793 IC50 11.0 nM
CCCCCCN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)N(CC)CC)[C@@]2(C)CCC(=O)C=C12 CHEMBL421696 IC50 12.0 nM
CCCCCCN1C[C@H]2[C@@H]3CC[C@H](C(=O)N(CC)CC)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 CHEMBL1762034 IC50 12.0 nM
C[C@]12CC[C@H](OC(=O)C3CCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(Cl)=C(C=O)C[C@@H]12 CHEMBL3342892 IC50 13.0 nM
CCCCCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17206 IC50 14.0 nM
Cc1ccc(Cc2ccc(C(=O)c3ccc(C(=O)O)cc3)cc2)cc1 CHEMBL289822 Ki app 15.0 nM
C[C@]12CC[C@H](OC(=O)C3CCCCCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(Cl)=C(C=O)C[C@@H]12 CHEMBL3342895 IC50 15.0 nM
C[C@]12CCC(=O)N[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(=O)Nc3ccccc3)CC[C@@H]12 CHEMBL4064645 IC50 15.0 nM
CC(=O)C1CC[C@H]2[C@@H]3CC=C4C=C(c5nnn[nH]5)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3753791 IC50 15.6 nM
CCCCCCCCN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL417627 IC50 18.4 nM
O=C(O)c1ccc(C(=O)c2ccc(Oc3ccc([N+](=O)[O-])cc3)cc2)cc1 CHEMBL285651 Ki app 20.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(O)cc3)cc2)cc1 CHEMBL286372 Ki app 22.0 nM
CCN1C(=O)CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL2172644 IC50 22.1 nM
CC(C)Cc1ccc([C@]2(C)Oc3ccc(C(=O)c4cn(CCCC(=O)O)c5ccccc45)cc3O2)cc1 CHEMBL279206 IC50 23.0 nM
O=C(O)Cc1ccc(C(=O)c2ccc(Oc3ccccc3)cc2)cc1 CHEMBL370016 IC50 23.0 nM
CN(C(=O)C1CCC2C3CCC4NC(=O)C=C[C@]4(C)C3CC[C@]12C)c1ccccc1 CHEMBL111407 IC50 24.6 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N(c1ccccc1)c1ccccc1 CHEMBL24191 IC50 25.2 nM
C[C@]12C=CC(=O)NC1CCC1C2CC[C@]2(C)C(C(=O)N(c3ccccc3)c3ccccc3)CCC12 CHEMBL321442 IC50 25.2 nM
CC(C)N(C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C(F)=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C CHEMBL2311127 Ki app 26.0 nM
CCOC(=O)CCN1C(=O)CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL2172647 IC50 26.5 nM
Cc1cc(CC(=O)O)ccc1C(=O)c1ccc(Oc2ccccc2)cc1 CHEMBL201762 IC50 27.0 nM
CC(=O)N1N=C(C2=CC[C@H]3[C@@H]4CC=C5C[C@@H](O)CC[C@]5(C)[C@H]4CC[C@]23C)C[C@H]1c1ccc(F)cc1 CHEMBL5182135 IC50 27.3 nM
CCCCN1CC2C(CC[C@@]3(C)C2CC[C@@H]3C(=O)N(CC)CC)[C@@]2(C)CCC(=O)C=C12 CHEMBL77378 IC50 29.0 nM
CCCCN1C[C@H]2[C@@H]3CC[C@H](C(=O)N(CC)CC)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12 CHEMBL1762036 IC50 29.0 nM
C[C@]12CC[C@H](OC(=O)C3CCCCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(C(=O)Cn3ccnc3)=CC[C@@H]12 CHEMBL4085478 IC50 29.3 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC[C@H]4C=C([N+](=O)[O-])CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL110001 Ki app 30.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC[C@H]4C=C(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL48467 Ki app 30.0 nM
COc1cc2cc(C(=O)O)[nH]c2cc1OCc1ccccc1 CHEMBL37880 Ki app 30.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(C(F)(F)F)cc3)cc2)cc1 CHEMBL35176 Ki app 30.0 nM
O=C(O)c1ccc(C(=O)c2ccc(Cc3ccc(C(F)(F)F)cc3)cc2)cc1 CHEMBL36688 Ki app 30.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)C3CCCCC3)cc2)cc1 CHEMBL34847 Ki app 30.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC(F)=C4C=C(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL172595 Ki app 32.0 nM
C[C@]12CCC(=O)C=C1NCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N1CCNCC1 CHEMBL310710 IC50 33.0 nM
C[C@]12CC[C@H]3[C@@H](CNC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)N1CCNCC1 CHEMBL2282770 IC50 33.0 nM
O=C(O)CCCn1cc(C(=O)c2ccc3c(c2)OC(c2ccccc2)(c2ccccc2)O3)c2ccccc21 CHEMBL287906 Potency 34.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(Cl)cc3Cl)cc2)cc1 CHEMBL37091 Ki app 35.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(Cl)cc3)cc2)cc1 CHEMBL287996 Ki app 35.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(Cl)c(Cl)c3)cc2)cc1 CHEMBL34924 Ki app 35.0 nM
O=C(O)c1ccc(Cc2ccc(Oc3ccccc3)cc2)cc1 CHEMBL35884 Ki app 35.0 nM
CC1=C(C(=O)O)CC[C@@]2(C)C1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2C(=O)N(C(C)C)C(C)C CHEMBL422046 Ki app 35.0 nM
C[C@]12CC[C@H](OC(=O)C3CCCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(C(=O)Cn3ccnc3)=CC[C@@H]12 CHEMBL4063904 IC50 35.0 nM
C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3ccn(-c4ccc(Cl)cc4)n3)=CC[C@@H]12 CHEMBL5188574 IC50 35.3 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3cccc(C(F)(F)F)c3)cc2)cc1 CHEMBL36022 Ki app 38.0 nM
O=C(O)c1cc2cc(OCc3ccccc3)ccc2[nH]1 CHEMBL24850 Ki 40.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(Cc4ccccc4)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL76671 IC50 40.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccccc3)cc2)cc1 CHEMBL37660 Ki app 40.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)Cc3ccccc3)cc2)cc1 CHEMBL264757 Ki app 40.0 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(Cc4ccccc4)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282663 IC50 40.0 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4C(=O)N(C(=O)NC4CCCCC4)C4CCCCC4)C3CCC12 CHEMBL262635 IC50 41.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC[C@H]4NC(=O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL297697 IC50 41.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CN(C#N)C4=CC(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL305932 IC50 42.0 nM
CCN(CC)C(=O)[C@H]1CC[C@H]2[C@@H]3CN(C#N)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2282667 IC50 42.0 nM
O=C(O)Cc1ccc(C(=O)c2ccc(Oc3ccccc3)cc2)c(F)c1 CHEMBL382214 IC50 45.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C(C(=O)O)CC[C@@H]4C3CC[C@@]21C)C(C)C CHEMBL366660 Ki app 50.0 nM
C[C@]12CC[C@H](OC(=O)C3CCCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(Cl)=C(C=O)C[C@@H]12 CHEMBL3342893 IC50 50.0 nM
CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@@H]2CC[C@]2(C)C(Cl)=C(C=O)C[C@@H]32)C1 CHEMBL3342896 IC50 50.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CCC4=CC(C(=O)O)=CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL172416 Ki app 52.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(C#Cc4ccccc4)cc3CC[C@@H]12 CHEMBL128303 IC50 52.0 nM
CN1C(=O)CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL2172643 IC50 54.1 nM
CC(C)NC(=O)N(C(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4N(C)C(=O)CC[C@]4(C)[C@H]3CC[C@]12C)C(C)C CHEMBL1908332 IC50 55.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)C(C3CCCCC3)C3CCCCC3)CC2)cc1 CHEMBL424066 IC50 60.0 nM
O=C(O)c1ccc(-c2ccc(C(=O)Cc3ccccc3)cc2)cc1 CHEMBL37254 Ki app 60.0 nM
O=C(O)c1ccc(C(O)c2ccc(Oc3ccccc3)cc2)cc1 CHEMBL286363 Ki app 60.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C(C(=O)O)C=C[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL427113 Ki app 60.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC[C@H]4C=C(C(=O)O)C=C[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL172025 Ki app 62.0 nM
CC(C)Cc1ccc([C@@H](C)Oc2ccc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)cc2)cc1 CHEMBL280954 IC50 69.0 nM
CC(C)c1cc(-c2ccc(C(=O)O)cc2)cc(C(C)C)c1OCC(=O)N(C(C)C)C(C)C CHEMBL47679 IC50 71.0 nM
C[C@]12CCC(C(=O)O)=CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)NC(=O)CC[C@@H]12 CHEMBL1642918 IC50 71.0 nM
C=CCN1C(=O)CC[C@H]2[C@@H]3CC=C4C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL2172645 IC50 72.8 nM
C[C@]12CC[C@H](OC(=O)C3CCC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(C(=O)Cn3ccnc3)=CC[C@@H]12 CHEMBL4093235 IC50 76.4 nM
C[C@]12CCC(c3nnn[nH]3)=CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL3754525 IC50 83.8 nM
[3H]C1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@]3(C)C(=O)CC[C@H]3[C@H]12 CHEMBL2311155 IC50 83.9 nM
O=C(O)c1ccc(C(=O)c2ccc(-c3ccc(Cl)cc3Cl)cc2)cc1 CHEMBL37348 Ki app 85.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC[C@H]4CC(C(=O)O)=CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL172951 Ki app 85.0 nM
O=C(COc1c(F)cc(-c2ccc(C(=O)O)cc2)cc1[N+](=O)[O-])NC(c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL298709 IC50 92.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc([N+](=O)[O-])cc3)cc2)cc1 CHEMBL431904 Ki app 100.0 nM
CC(C)(C)c1ccc(C(=O)c2ccc(C(=O)c3ccc(C(=O)O)cc3)cc2)cc1 CHEMBL36441 Ki app 110.0 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@]4(C)C=C(C(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL2311126 Ki app 110.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CCC4=C(CCC(C(=O)O)=C4)C3CC[C@@]21C)C(C)C CHEMBL353340 Ki app 110.0 nM
O=C(O)c1ccc(C(=O)c2ccc(OCc3cc(C(F)(F)F)ccc3C(F)(F)F)cc2)cc1 CHEMBL201699 IC50 113.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(F)cc4)ccc3N2CCC1=O CHEMBL180235 IC50 119.0 nM
O=C(O)c1ccc(C(=O)c2ccc(OCc3ccccc3)cc2)cc1 CHEMBL202871 IC50 119.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc4c(c3)OCO4)cc2)cc1 CHEMBL36832 Ki app 120.0 nM
CC(C)(C)NC(=O)[C@@H]1CCC2C3CCC4=CC(=O)CCN4C3=CC[C@@]21C CHEMBL99615 IC50 122.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)C=CC(=O)N(C)C1C[C@@H]3C CHEMBL128023 IC50 125.0 nM
COc1cc(C(=O)O)ccc1C=C1CCN(C(=O)C(C2CCCCC2)C2CCCCC2)CC1 CHEMBL114948 IC50 130.0 nM
O=C(O)c1ccc(C(=O)c2cccc(OCc3ccccc3)c2)cc1 CHEMBL382649 IC50 131.0 nM
CC1=C2CCc3cc(C(=O)Oc4cccc(F)c4)ccc3N2CCC1=O CHEMBL183185 IC50 134.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)N(C)C1=C[C@@H]3C CHEMBL421627 IC50 147.0 nM
CC(C)CCCC(C)[C@H]1CCC2C3C(CC[C@@]21C)[C@@]1(C)CCC(=O)N(C)C1C[C@@H]3C CHEMBL25448 IC50 154.0 nM
C=CCN1C(=O)CC[C@H]2[C@@H]3CC=C4C=C(c5nnn[nH]5)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL3754321 IC50 157.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccccc4F)ccc3N2CCC1=O CHEMBL425878 IC50 166.0 nM
CCN(CC)C(=O)[C@H]1CCC2C3CNC4=C(CN(C)C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL311818 IC50 170.0 nM
CC1=C2C=C(C(=O)O)CC[C@]2(C)C2CC[C@@]3(C)C(CC[C@@H]3C(=O)N(C(C)C)C(C)C)C2C1 CHEMBL367878 Ki app 170.0 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(O)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL36573 IC50 172.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4ccccc4)cc3CC[C@@H]12 CHEMBL300446 IC50 180.0 nM
CCC1=C2NCC3C(CC[C@@]4(C)C3CC[C@@H]4C(=O)N(CC)CC)[C@@]2(C)CCC1=O CHEMBL80520 IC50 180.0 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(Cl)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL277403 IC50 192.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CCC4=C[C@@H](C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL170233 Ki app 200.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)C34CC5CC(CC(C5)C3)C4)CC2)c(F)c1 CHEMBL115123 IC50 210.0 nM
CN1C(=O)CC[C@]2(C)C3CC[C@@]4(C)C(CC[C@@H]4C(=O)N(C(=O)NC(C)(C)C)C(C)(C)C)C3CCC12 CHEMBL25282 IC50 212.0 nM
C[C@]12CC[C@H]3[C@@H](CC=C4C=C(C(=O)O)CC[C@@H]43)[C@@H]1CCC2=O CHEMBL2172650 IC50 212.9 nM
CC(C)CCCC(C)[C@H]1CCC2C3CCC4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL24193 IC50 218.0 nM
CC(C)CCCC(C)C1CCC2C3CCC4NC(=O)CC[C@]4(C)C3CC[C@]12C CHEMBL340181 IC50 218.0 nM
CC(C)CCCC(C)C1CCC2C3CCC4N(C)C(=O)CC[C@]4(C)C3CC[C@]12C CHEMBL340027 IC50 218.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CCC4=C[C@](O)(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL2110261 Ki app 220.0 nM
C[C@]12CCC(c3nnn[nH]3)=CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)NC(=O)CC[C@@H]12 CHEMBL3752475 IC50 220.1 nM
O=C(O)c1cc2ccccc2[nH]1 CHEMBL278390 Ki app 230.0 nM
CC(=O)Nc1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL182399 IC50 255.0 nM
Cc1c(O[C@@H](C)c2ccc(CC(C)C)cc2)ccc(C(=O)Nc2ccccc2OCCCC(=O)O)c1C CHEMBL24470 IC50 256.0 nM
C[C@]12CCC(C(=O)O)=CC1=CCc1cc(Cl)ccc12 CHEMBL25081 Ki 260.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)C34CC5CC(CC(C5)C3)C4)CC2)cc1 CHEMBL114114 IC50 260.0 nM
CC12CCC(C(=O)O)=CC1=CCc1cc(Cl)ccc12 CHEMBL308806 Ki app 260.0 nM
O=C(O)CCCOc1ccccc1-c1cc2ccc(C(=O)NC(c3ccccc3)c3ccccc3)cc2o1 CHEMBL152401 IC50 270.0 nM
CN1C(=O)CC[C@H]2[C@@H]3CC=C4C=C(c5nnn[nH]5)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL3753825 IC50 273.8 nM
CC[C@H]1CC2NC(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL340684 IC50 280.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)NC1C[C@@H]3C CHEMBL340715 IC50 280.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccccc4)ccc3N2CCC1=O CHEMBL118283 IC50 295.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)C=CC(=O)NC1C[C@@H]3C CHEMBL126686 IC50 298.0 nM
CC12CCC(=O)C=C1CCC1C2CCC2(C)C(C/C=N/O)CCC12 CHEMBL135993 IC50 300.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C(N)=O)cc4)ccc3N2CCC1=O CHEMBL362379 IC50 308.0 nM
Cn1c(C(=O)O)cc2cc(OCc3ccccc3)ccc21 CHEMBL37725 Ki app 310.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CCC4=C[C@@](O)(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL172525 Ki app 320.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4cnc5ccccc5c4)cc3CC[C@@H]12 CHEMBL130845 IC50 320.0 nM
CC[C@H]1CC2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL127702 IC50 330.0 nM
O=C(O)CCCOc1ccccc1-c1cc2ccc(C(=O)NC(c3ccc(F)cc3)c3ccc(F)cc3)cc2o1 CHEMBL153258 IC50 340.0 nM
O=C(O)c1ccc2c(c1)CCc1cc(/C=C/c3ccccc3)ccc1-2 CHEMBL55402 IC50 340.0 nM
CCc1cc(-c2ccc(C(=O)O)cc2)ccc1OCC(=O)N(C(C)C)C(C)C CHEMBL297174 IC50 350.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccccc4C(F)(F)F)ccc3N2CCC1=O CHEMBL183167 IC50 368.0 nM
CCN(CC)C(=O)c1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL181196 IC50 372.0 nM
CC(C)NC(=O)N(C(=O)[C@H]1CCC2C3CCC4NC(=O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL278860 IC50 381.0 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(Br)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL283564 IC50 387.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)C(c3ccccc3)c3ccccc3)CC2)c(F)c1 CHEMBL117881 IC50 410.0 nM
CC(C)CCCC(C)[C@H]1CCC2C3C(CC[C@@]21C)[C@@]1(C)CCC(=O)N(C)C1C[C@@H]3c1ccccc1 CHEMBL280387 IC50 428.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)N(C)C1C[C@@H]3c1ccccc1 CHEMBL339912 IC50 428.0 nM
O=C(O)c1ccc(OC2CCN(C(=O)C34CC5CC(CC(C5)C3)C4)CC2)cc1 CHEMBL115019 IC50 430.0 nM
C/C(CC1CCC2C3CC(=O)C4=CC(=O)CCC4(C)C3CCC12C)=N\O CHEMBL136097 IC50 430.0 nM
C[C@]12CC[C@H](O)C=C1CC[C@H]1C3CC/C(=C/C=N\O)[C@@]3(C)CC[C@@H]12 CHEMBL2112735 IC50 430.0 nM
CC(C)(C)NC(=O)[C@H]1CCC2C3CCC4=C(S)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL24464 IC50 437.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)NC1C[C@@H]3c1ccccc1 CHEMBL124803 IC50 443.0 nM
CN1C(=O)CCC2=C1CCc1cc(Cl)ccc12 CHEMBL16456 Ki app 455.0 nM
COC(=O)c1cccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)c1 CHEMBL116370 IC50 467.0 nM
C/C(CC1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC12C)=N\O CHEMBL137040 IC50 470.0 nM
O=C(O)/C=C/c1ccc(C(=O)c2ccc(Oc3ccccc3)cc2)cc1 CHEMBL201736 IC50 470.0 nM
C[C@]12CCC(=O)C=C1CCC1C2CC[C@]2(C)C(n3cnc4ccccc43)=CCC12 CHEMBL77789 IC50 480.0 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C=C(F)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL4535229 IC50 480.0 nM
CC(C)Cc1ccc(C(C)Oc2ccc(C(=O)N3CC(CCCC(=O)O)c4ccccc43)cc2)cc1 CHEMBL35717 Potency 481.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(CC(=O)Nc4ccccc4)cc3CC[C@@H]12 CHEMBL334649 IC50 520.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)C(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL115298 IC50 530.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(/C=C/c4ccc5ccccc5n4)cc3CC[C@@H]12 CHEMBL341004 IC50 550.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(C)cc4)ccc3N2CCC1=O CHEMBL120923 IC50 553.0 nM
CC(C)N(C(=O)COc1ccc(-c2ccc(C(=O)O)cc2C(F)(F)F)cc1)C(C)C CHEMBL47785 IC50 570.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CCC4=C[C@H](C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL170282 Ki app 570.0 nM
CN1CC(c2ccc(/N=N/c3ccccc3)cc2)CCC1=O CHEMBL56908 IC50 579.0 nM
C/C(=N/O)[C@H]1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C CHEMBL135651 IC50 580.0 nM
CCC[C@H]1CC2N(C)C(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL126968 IC50 580.0 nM
CC(C)C(=O)N(c1ccccc1)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL266519 IC50 582.0 nM
COC(=O)c1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL122359 IC50 584.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC=C4C=C([N+](=O)[O-])CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL283546 Ki app 590.0 nM
CN1CC(c2ccc(/C=C/c3ccccc3)cc2)CCC1=O CHEMBL56518 IC50 617.0 nM
CCCNC(=O)c1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 CHEMBL182945 IC50 665.0 nM
CC(C)N(C(=O)[C@H]1CCC2C3CC(C(F)(F)F)=C4C=C(C(=O)O)CC[C@]4(C)C3CC[C@@]21C)C(C)C CHEMBL435332 IC50 700.0 nM
C[C@]12CC[C@H](OC(=O)C3CC3)CC1=CC[C@@H]1[C@@H]2CC[C@]2(C)C(C(=O)Cn3ccnc3)=CC[C@@H]12 CHEMBL4072502 IC50 711.0 nM
CCC[C@H]1C=C2NC(=O)CC[C@]2(C)C2CC[C@]3(C)C(C(C)CCCC(C)C)CCC3C21 CHEMBL124750 IC50 713.0 nM
C[C@]12CCC(C(=O)O)=CC1=CCC1C2CC[C@@]2(C)C1CC[C@@H]2C#N CHEMBL170473 Ki app 790.0 nM
O=C(O)c1ccc(C(=O)c2ccc(OC(c3ccccc3)c3ccccc3)cc2)cc1 CHEMBL203352 IC50 790.0 nM
CC1=C2CCc3cc(C(=O)Oc4ccc(N)cc4)ccc3N2CCC1=O CHEMBL183500 IC50 801.0 nM
O=C(O)c1ccc(C=C2CCN(C(=O)N(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL114594 IC50 830.0 nM
CC(C)N(C(=O)COc1ccc(-c2ccc(C(=O)O)cc2)cc1)C(C)C CHEMBL45671 IC50 830.0 nM
CC(C)CCCC(C)C1CCC2C3C(CC[C@]12C)[C@@]1(C)CCC(=O)NC1=C[C@@H]3C CHEMBL338376 IC50 859.0 nM
CC(C)N(C(=O)COc1ccc(-c2ccc(C(=O)O)cc2Cl)cc1)C(C)C CHEMBL45241 IC50 870.0 nM
CN1C(=O)CC[C@]2(C)c3ccc(CC(=O)O)cc3CC[C@@H]12 CHEMBL128342 IC50 870.0 nM
COc1ccc(C(NC(=O)c2ccc3cc(-c4ccccc4OCCCC(=O)O)oc3c2)c2ccc(OC)cc2)cc1 CHEMBL155094 IC50 930.0 nM
CN1C(=O)CC[C@@H]2c3ccc(Cl)cc3CC[C@H]21 CHEMBL24955 Ki app 1000.0 nM
CN1C(=O)CC[C@@H]2c3ccc(Cl)cc3CC[C@@H]21 CHEMBL281204 Ki app 1000.0 nM
O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(C(=O)O)cc3)cc2)cc1 CHEMBL35997 Ki app 1000.0 nM
CN(C=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL17193 IC50 1000.0 nM
CCCCCN(C(=O)CCCCBr)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@@]21C CHEMBL274269 IC50 1000.0 nM
CC1=C2CCc3cc(C(=O)Oc4cccc(C(F)(F)F)c4)ccc3N2CCC1=O CHEMBL183820 IC50 1000.0 nM