CCc1cc2c(cc1-c1cccc(S(=O)(=O)F)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O CHEMBL4468747 IC50 2.54 nM
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 CHEMBL1908397 Kd 15.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL502835 Kd 36.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 51.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 67.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3c(F)c(Cl)ccc3[nH]2)n1)S(C)(=O)=O CHEMBL5085558 IC50 80.0 nM
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL1287853 Kd 100.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(Cl)ccc3n2C)n1)S(C)(=O)=O CHEMBL5435975 IC50 147.0 nM
CN(c1ncccc1CNc1cccc(-c2nc3cc(Cl)ccc3[nH]2)n1)S(C)(=O)=O CHEMBL5397100 IC50 147.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 190.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 200.0 nM
COc1cc(/C=C2/C(=N)N3N=C(C(F)(F)F)SC3=NC2=O)ccc1O CHEMBL4787157 IC50 203.0 nM
CN(c1ncccc1Cn1ccc2cnc(-c3nc4cc(Cl)ccc4[nH]3)cc21)S(C)(=O)=O CHEMBL5405335 IC50 210.0 nM
O=C(Nc1cc(C(F)(F)F)ccc1N1CCN(Cc2ccccn2)CC1)c1ccc(-c2ccncc2)o1 CHEMBL5074274 IC50 256.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(Cl)cc(F)c3[nH]2)n1)S(C)(=O)=O CHEMBL5439515 IC50 260.0 nM
CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 CHEMBL522892 Kd 290.0 nM
CN(c1ncccc1Cn1ccc2cnc(-c3nc4cc(Cl)ccc4[nH]3)nc21)S(C)(=O)=O CHEMBL5416930 IC50 300.0 nM
CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL608533 Kd 330.0 nM
Cc1cc2cnc(-c3nc4cc(Cl)ccc4[nH]3)nc2n1Cc1cccnc1N(C)S(C)(=O)=O CHEMBL5437009 IC50 340.0 nM
CN(c1ncccc1CNc1nc(-c2nc3cc(Cl)ccc3[nH]2)ncc1Br)S(C)(=O)=O CHEMBL5409896 IC50 460.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1 CHEMBL450786 Kd 500.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(Cl)ccc3[nH]2)n1)S(C)(=O)=O CHEMBL5407046 IC50 510.0 nM
CN(Cc1cccnc1N(C)S(C)(=O)=O)c1ccnc(-c2nc3cc(Cl)ccc3[nH]2)n1 CHEMBL5409387 IC50 626.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(F)cc(Cl)c3[nH]2)n1)S(C)(=O)=O CHEMBL5398076 IC50 660.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(Cl)c(F)cc3[nH]2)n1)S(C)(=O)=O CHEMBL5399262 IC50 670.0 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 CHEMBL572878 Kd 680.0 nM
CC(C)c1ccc2[nH]c(-c3nccc(NCc4cccnc4N(C)S(C)(=O)=O)n3)nc2c1 CHEMBL5433267 IC50 750.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(F)cc(F)c3[nH]2)n1)S(C)(=O)=O CHEMBL5422948 IC50 870.0 nM
CN(c1ncccc1CNc1ccnc(-c2nc3cc(-c4cnn(C)c4)ccc3[nH]2)n1)S(C)(=O)=O CHEMBL5403164 IC50 900.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM