Cc1cc(-c2ccc(F)cc2)n2ncc(-c3ccccc3)c2n1 CHEMBL1398377 EC50 64.3 nM
CCOC(=O)/C(C#N)=C/c1cc(C)n(-c2ccccc2)c1C CHEMBL1332452 EC50 69.0 nM
CNC(=O)c1cnc2[nH]ccc2c1N[C@H]1CCN(Cc2ccc(C(F)(F)F)cc2)[C@@H](C)C1 CHEMBL5397297 EC50 71.0 nM
COc1ccc(-c2csc(N3C(=O)CNC3=S)n2)cc1 CHEMBL1333621 EC50 87.0 nM
Cc1nnc(SCC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2)s1 CHEMBL1328302 EC50 93.0 nM
COc1cccc(N/C=C/C(=O)c2ccc(Cl)cc2)c1 CHEMBL1523697 EC50 114.0 nM
COc1ccc(-c2nc3cc([N+](=O)[O-])ccc3[nH]2)cc1 CHEMBL1535921 EC50 126.0 nM
CCNc1nc(-c2cc3ccccc3o2)cs1 CHEMBL1604696 EC50 179.0 nM
O=C(/C=C/c1cccc(F)c1)N1CCc2ccccc21 CHEMBL1450911 EC50 210.0 nM
CCOC(=O)c1cnc2c(-c3ccccc3)cnn2c1N CHEMBL1577902 EC50 229.0 nM
CCOC(=O)c1sc(NC(=O)c2sccc2C)cc1C CHEMBL1559414 EC50 233.0 nM
CCCC(C)Oc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N[C@@H](C)c4ccc(OC)cc4)sc3c2)c(OC)c1C CHEMBL4846365 IC50 320.0 nM
c1cncc(-c2nc3cc4ccccc4cc3[nH]2)c1 CHEMBL1465006 EC50 331.0 nM
O=C(Nc1ccc(-c2nc3cccnc3s2)cc1)c1ccco1 CHEMBL1571018 EC50 341.0 nM
CCCC(C)Oc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N[C@@H](C)c4ccccc4)sc3c2)c(OC)c1C CHEMBL4864495 IC50 350.0 nM
Cc1nc2cc(-c3nc4ccccc4o3)ccc2[nH]1 CHEMBL1334210 EC50 356.0 nM
Clc1ccc(-n2ncc3c(NCC4CCCO4)ncnc32)cc1 CHEMBL1543167 EC50 409.0 nM
CC(C)Oc1ccc2c(=O)c(-c3ccccc3)coc2c1 CHEMBL165790 EC50 418.0 nM
CN1C(=O)/C(=C/C=C2\SCCN2C)SC1=S CHEMBL1543182 EC50 420.0 nM
O=C(/C=C/Nc1ccc(F)cc1)c1ccc(Br)cc1 CHEMBL1531634 EC50 431.0 nM
CCCOC(=O)c1ccc(-c2ccc(C=O)o2)cc1 CHEMBL1453960 EC50 436.0 nM
NC(=O)Cc1ccc2sc(-c3ccccc3)nc2c1 CHEMBL1406726 EC50 463.0 nM
Nc1nc2ccc(-c3nc4ccccc4o3)cc2s1 CHEMBL1563821 EC50 516.0 nM
O=C(NC(=S)Nc1ccccn1)c1ccc([N+](=O)[O-])cc1 CHEMBL1430765 EC50 525.0 nM
O=C(/C=C/c1ccccc1)Nc1ccc(Cl)cn1 CHEMBL1366272 EC50 669.0 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL297453 Kd 700.0 nM
CCCCOC(=O)Nc1nc2ccccc2s1 CHEMBL1458453 EC50 741.0 nM
CCc1ccc(Nc2ncc3c(n2)CC(C)CC3=O)cc1 CHEMBL1496911 EC50 751.0 nM
O=C(Nc1cccc(Cl)c1)c1ccc2c(=O)n3c(nc2c1)CCCCC3 CHEMBL1518405 EC50 811.0 nM
CC(C)(C)NC1=NN=C(c2cc3ccccc3o2)CS1 CHEMBL1408441 EC50 825.0 nM
C=CCNC(=O)c1cc(-c2ccc(Br)cc2)on1 CHEMBL1381396 EC50 832.0 nM
O=C(Nc1nc2ccccc2s1)c1cc2ccccc2s1 CHEMBL1316867 EC50 834.72 nM
CCCCCNc1nc(-c2ccccc2)cs1 CHEMBL1501717 EC50 851.0 nM
CC(=O)C1=CC2C(=O)c3ccccc3C(=O)C2O1 CHEMBL4846078 IC50 880.0 nM
O=C(/C=C/c1ccc(F)cc1)Nc1nc2ccccc2[nH]1 CHEMBL1423409 EC50 920.0 nM
NC(=O)CC[C@H](NC(=O)[C@@H]1CC[C@@H]2CCN(C(=O)CCCCCC#Cc3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)C[C@H](NC(=O)c3cc4cc(C(F)(F)P(=O)(O)O)ccc4[nH]3)C(=O)N21)C(=O)NC(c1ccccc1)c1ccccc1 CHEMBL4452527 Kd 1000.0 nM