Nc1ncnc2c1ncn2[C@@H]1O[C@@H](CO)[C@H](O)[C@@H]1O CHEMBL1413677 Potency 0.03162 nM
Cc1ccccc1-c1nn2c(-c3ccccc3)nnc2s1 CHEMBL1547481 Potency 0.2 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1c(F)cc(F)cc1F CHEMBL487451 IC50 0.7 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1c(F)ccc(F)c1F CHEMBL593171 IC50 0.7 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1F CHEMBL470963 IC50 1.4 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cc(F)ccc1F CHEMBL488814 IC50 1.6 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cc(F)cc(F)c1F CHEMBL519249 IC50 1.8 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(F)c1 CHEMBL512874 IC50 1.8 nM
NC(=O)CN1CCN(c2ccc(Nc3ncc4ccn(Cc5cc(F)cc(F)c5)c4n3)cc2)CC1 CHEMBL595058 IC50 1.9 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(F)c1F CHEMBL529443 IC50 2.1 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1c(F)cccc1F CHEMBL519410 IC50 2.2 nM
CN1CCN(c2ccc(Nc3ncc4ccn(Cc5cc(F)cc(F)c5)c4n3)cc2)CC1 CHEMBL596420 IC50 3.2 nM
CNC(=O)CN1CCN(c2ccc(Nc3ncc4ccn(Cc5cc(F)cc(F)c5)c4n3)cc2)CC1 CHEMBL606350 IC50 4.7 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cc(F)cc(F)c1 CHEMBL487450 IC50 5.5 nM
OCCN1CCN(c2ccc(Nc3ncc4ncn(Cc5cc(F)cc(F)c5)c4n3)cc2)CC1 CHEMBL596421 IC50 5.6 nM
CN1CCN(c2ccc(Nc3ncc(C(N)=O)c(NCc4ccccc4)n3)cc2)CC1 CHEMBL470949 IC50 6.2 nM
COC(=O)C(O)(c1ccc(NC(=O)c2ccco2)c(OC)c1)C(F)(F)F CHEMBL1380504 Potency 6.3 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1 CHEMBL471114 IC50 6.5 nM
NC(=O)c1cnc(Nc2ccc(N3CCNCC3)cc2)nc1NCc1ccccc1 CHEMBL471113 IC50 7.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1Cl CHEMBL471131 IC50 7.9 nM
COc1ccccc1CNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1C(N)=O CHEMBL469910 IC50 8.2 nM
Cc1ccccc1CNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1C(N)=O CHEMBL512533 IC50 11.0 nM
Fc1cc(F)cc(Cn2ccc3cnc(Nc4ccc(N5CCNCC5)cc4)nc32)c1 CHEMBL594344 IC50 12.0 nM
CCCCCCc1cc2cc(-c3nnc(-c4ccccc4O)o3)c(=O)oc2cc1O CHEMBL1544947 Potency 12.6 nM
NC(=O)c1cnc(Nc2ccc(N3CCC(O)CC3)cc2)nc1NCc1ccccc1 CHEMBL517122 IC50 16.0 nM
CN1CCC(c2ccc(Nc3ncc(C(N)=O)c(NCc4ccccc4)n3)cc2)CC1 CHEMBL513401 IC50 17.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(O)c1 CHEMBL487460 IC50 19.0 nM
C/C1=C\CC[C@H](C)[C@@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5280678 IC50 20.0 nM
NC(=O)c1cnc(NCCc2ccc(O)c(Cl)c2)nc1NCc1ccccc1 CHEMBL228192 IC50 21.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1O CHEMBL471130 IC50 22.0 nM
CSc1ccccc1CNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1C(N)=O CHEMBL486643 IC50 23.0 nM
COc1cccc(CNc2nc(Nc3ccc(N4CCOCC4)cc3)ncc2C(N)=O)c1 CHEMBL471743 IC50 25.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1C(F)(F)F CHEMBL512519 IC50 25.0 nM
O=C(O)CN1CCN(c2ccc(Nc3ncc4ccn(Cc5cc(F)cc(F)c5)c4n3)cc2)CC1 CHEMBL595488 IC50 26.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccc(I)cc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3741938 IC50 28.0 nM
CNC(=O)c1cnc(NCCc2ccc(O)c(Cl)c2)nc1NCc1ccccc1 CHEMBL226930 IC50 30.0 nM
NCCN1CCN(c2ccc(Nc3ncc4ccn(Cc5cc(F)cc(F)c5)c4n3)cc2)CC1 CHEMBL594821 IC50 34.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(Cl)c1 CHEMBL471559 IC50 36.0 nM
Fc1cccc(Cn2ccc3cnc(Nc4ccc(N5CCOCC5)cc4)nc32)c1 CHEMBL603203 IC50 37.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1[N+](=O)[O-] CHEMBL520234 IC50 38.0 nM
CC(C)(C)[C@H](NC(=O)/C=C/c1ccc(OP(=O)(O)O)cc1)C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccc(I)cc1 CHEMBL3741162 IC50 44.0 nM
Cc1cccc(Nc2nc(NCCc3ccc(O)c(Cl)c3)ncc2C(N)=O)c1 CHEMBL228018 IC50 45.0 nM
C/C1=C\C[C@H](O)[C@H](C)[C@@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5410106 IC50 50.0 nM
C/C1=C\C[C@@H](O)[C@H](C)[C@@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5267203 IC50 56.0 nM
NC(=O)c1cnc(NCCc2cc(Cl)c(O)c(Cl)c2)nc1NCc1ccccc1 CHEMBL518350 IC50 61.0 nM
Cc1cccc(Nc2nc(NCCc3ccc(O)c(F)c3)ncc2C(N)=O)c1 CHEMBL387668 IC50 64.0 nM
C/C1=C/C[C@H](O)[C@H](C)[C@@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5439266 IC50 64.0 nM
C/C1=C\CCC(C)(O)C(C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL3400936 IC50 68.0 nM
C/C1=C/C[C@@H](O)[C@H](C)[C@@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5405214 IC50 72.0 nM
C/C1=C\CCC(C)(C)C(C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5271361 IC50 79.0 nM
NC(=O)c1cnc(Nc2ccc(CCCO)cc2)nc1NCc1ccccc1 CHEMBL461721 IC50 81.0 nM
Cc1cccc(Nc2nc(NCCc3ccc(O)c(Br)c3)ncc2C(N)=O)c1 CHEMBL389647 IC50 83.0 nM
NC(=O)c1cnc(NCCc2ccc(O)cc2)nc1NCc1ccccc1 CHEMBL374380 IC50 88.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1c(F)cc(F)cc1F CHEMBL488307 IC50 88.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3741886 IC50 89.0 nM
NC(=O)c1cnc(Nc2ccc(CCO)cc2)nc1NCc1ccccc1 CHEMBL461720 IC50 95.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCC(O)C3)cc2)nc1NCc1ccccc1 CHEMBL458325 IC50 98.0 nM
NC(=O)c1cnc(NCCc2ccc(O)cc2)nc1NC1CCCCC1 CHEMBL427436 IC50 100.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCCCC3)cc2)nc1NCc1ccccc1 CHEMBL461304 IC50 120.0 nM
Fc1cc(F)cc(Cn2ccc3cnc(Nc4ccc(N5CCOCC5)cc4)nc32)c1 CHEMBL596223 IC50 120.0 nM
CC(C)(C)[C@H](NC(=O)/C=C/c1ccc(OP(=O)(O)O)cc1)C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccccc1 CHEMBL3740709 IC50 120.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(C)c1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3739524 IC50 120.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N(C)c1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3741674 IC50 120.0 nM
Cc1cccc(Nc2nc(NCCc3ccc(O)c(C)c3)ncc2C(N)=O)c1 CHEMBL226770 IC50 130.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(C(F)(F)F)c1 CHEMBL471560 IC50 130.0 nM
CC(C)(C)[C@H](NC(=O)c1cc2cc(OP(=O)(O)O)ccc2[nH]1)C(=O)N1CCC[C@H]1C(=O)N(c1ccccc1)c1ccc(I)cc1 CHEMBL3742125 IC50 140.0 nM
CNC(=O)c1cnc(NCCc2ccc(O)cc2)nc1Nc1cccc(C)c1 CHEMBL227748 IC50 170.0 nM
Cc1cccc(Nc2nc(NCCc3ccc(O)cc3)ncc2C(N)=O)c1 CHEMBL376085 IC50 190.0 nM
COc1ccc(C[C@@H]2C(=O)N[C@H](C)C(=O)N(C)[C@@H]3Cc4ccc(cc4)Oc4cc(ccc4O)C[C@H](C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N2C)N(C)C3=O)cc1 CHEMBL1475206 Potency 199.5 nM
C/C1=C\C[C@H](O)[C@H](C)[C@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5434170 IC50 200.0 nM
CN(C)C(=O)CCN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1cc2cc(C(F)(F)P(=O)(O)O)ccc2s1)C(C)(C)C)c1ccc2ccccc2c1 CHEMBL5402407 Ki 200.0 nM
CN(C)C(=O)CCN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1cc2cc(C(F)(F)P(=O)(O)O)ccc2s1)C(C)(C)C)c1ccc2occc2c1 CHEMBL5396273 Ki 200.0 nM
Fc1ccccc1Cn1ccc2cnc(Nc3ccc(N4CCOCC4)cc3)nc21 CHEMBL596410 IC50 220.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(C)C1CCCCC1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3741189 IC50 230.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3739968 IC50 250.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)Nc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3740710 IC50 270.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N(C)CC(=O)N(C)c1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3741243 IC50 270.0 nM
CN(C)C(=O)CCN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1cc2cc(C(F)(F)P(=O)(O)O)ccc2s1)C(C)(C)C)c1ccc(Cl)cc1 CHEMBL5398612 Ki 300.0 nM
CN(C)C(=O)CCN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1cc2cc(C(F)(F)P(=O)(O)O)ccc2s1)C(C)(C)C)c1ccc(Br)cc1 CHEMBL5430356 Ki 300.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccc(F)cc1F CHEMBL488649 IC50 310.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1N CHEMBL487634 IC50 310.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3739875 IC50 340.0 nM
CCNC(=O)c1cnc(NCCc2ccc(O)cc2)nc1Nc1cccc(C)c1 CHEMBL389452 IC50 380.0 nM
CCN(CC)C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)/C=C(\C)c1ccc(OP(=O)(O)O)cc1)C(C)(C)C CHEMBL3739525 IC50 380.0 nM
CC[C@@H]1CN2CCc3cc(OC)c(OC)cc3[C@H]2C[C@@H]1C[C@@H]1NCCc2cc(OC)c(OC)cc21 CHEMBL1435868 Potency 398.1 nM
COc1ccc(C[C@@H]2C(=O)N[C@H](C)C(=O)N(C)[C@@H]3C(=O)N(C)[C@@H](Cc4ccc(O)c(c4)Oc4ccc(cc4)[C@H]3O)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N2C)cc1 CHEMBL1530314 Potency 398.1 nM
OC[C@@H]1O[C@@H](n2cnc3c(SCc4ccccc4)ncnc32)[C@@H](O)[C@H]1O CHEMBL1530640 Potency 398.1 nM
CC(=O)Oc1ccc(C(c2ccc(OC(C)=O)cc2)c2ccccn2)cc1 CHEMBL942 Potency 398.1 nM
c1ccc(Cn2ccc3cnc(Nc4ccc(N5CCOCC5)cc4)nc32)cc1 CHEMBL593392 IC50 400.0 nM
CN(C)C(=O)CCN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1cc2cc(C(F)(F)P(=O)(O)O)ccc2s1)C(C)(C)C)c1ccc2scnc2c1 CHEMBL5438554 Ki 400.0 nM
NC(=O)c1cnc(NCCc2ccc(O)cc2)nc1Nc1ccccc1 CHEMBL227804 IC50 410.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCCC1CN(C)c1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3742269 IC50 410.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N(C)[C@@H](C)C(=O)N(C)c1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3740699 IC50 480.0 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCCC1/C=C/CCc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3740610 IC50 540.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccc(F)cc1 CHEMBL470964 IC50 650.0 nM
NC(=O)c1cnc(Nc2ccc(N3CCCC3)cc2)nc1NCc1ccccc1 CHEMBL461303 IC50 650.0 nM
CC(C)[C@@H](C)NC(=O)c1cc(-c2cc3ccccc3n2C)cc(C(=O)NCCc2ccccn2)n1 CHEMBL2204367 Kd 655.6 nM
COc1cc(CCNc2ncc(C(N)=O)c(Nc3cccc(C)c3)n2)ccc1O CHEMBL388357 IC50 660.0 nM
CC(C)[C@@H](C)NC(=O)c1cc(-c2cc3ccccc3s2)cc(C(=O)NCCc2ccccn2)n1 CHEMBL2204366 Kd 701.4 nM
C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(C)C)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 CHEMBL3741667 IC50 740.0 nM
CC(=O)[C@@]1(O)Cc2c(O)c3c(c(O)c2[C@H](O[C@H]2C[C@H](N)[C@H](O)[C@H](C)O2)C1)C(=O)c1ccccc1C3=O CHEMBL1515691 Potency 794.3 nM
CN(C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)/C=C/c1ccc(OP(=O)(O)O)cc1)C(C)(C)C)c1ccccc1 CHEMBL3740611 IC50 870.0 nM
COc1ccc2c(c1)c1c(C)c3cnccc3c(C)c1n2CCCN CHEMBL363332 Potency 1000.0 nM
C/C1=C\C[C@@H](O)[C@H](C)[C@H](C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O CHEMBL5403707 IC50 1000.0 nM