CCCCC(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL3797480 Ki 0.26 nM
CSc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL1836719 Kd 3.8 nM
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 CHEMBL1908397 Kd 4.8 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 5.0 nM
O=C(O)CSc1ncnc2cc(-c3cc4ccccc4s3)sc12 CHEMBL4752776 Kd 5.6 nM
C[S+]([O-])c1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4796519 IC50 7.0 nM
O=C1Nc2ccc(NC(=O)C3CC3)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL3799389 IC50 8.0 nM
Nc1c(-c2n[nH]c(=S)o2)sc2ncc(-c3ccsc3)cc12 CHEMBL4060481 Kd 8.0 nM
O=C(O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2F)=NC3)cc1 CHEMBL259084 Kd 8.1 nM
COc1ccc(-c2cnc3scc(NC(=O)C4CCCCC4)c3c2)cc1OC CHEMBL3334979 Kd 9.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 9.2 nM
CCCC(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL3799585 IC50 10.0 nM
COc1cnc(Nc2ccc(CS(C)(=O)=O)cc2)nc1Nc1cc(C2CC2)[nH]n1 CHEMBL5433785 IC50 10.0 nM
NC(=O)c1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL1836721 Kd 11.0 nM
CC(=O)c1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4760126 IC50 13.0 nM
CC(C)=CC(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL3797466 IC50 14.0 nM
CC(C)(C)CC(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL3799505 IC50 14.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(N4CCOCC4)cc3)sc12 CHEMBL4753926 IC50 14.0 nM
COc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1F CHEMBL4763132 IC50 18.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 21.0 nM
CC(C)(C)C(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL513703 IC50 21.0 nM
CC(=O)Nc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL1836724 IC50 23.0 nM
COc1ccc(-c2cnc3scc(NC(=O)C4CCCCC4)c3n2)cc1OC CHEMBL3334980 Kd 27.0 nM
CSc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1F CHEMBL4754748 IC50 27.0 nM
C=Cc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4794509 IC50 28.0 nM
O=C(O)COc1ncnc2cc(-c3ccc4[nH]ncc4c3)sc12 CHEMBL1836641 Kd 30.0 nM
COc1ccc(-c2cnc3[nH]cc(NC(=O)C4CCCCC4)c3c2)cc1OC CHEMBL3334981 Kd 33.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(C(F)(F)F)cc3)sc12 CHEMBL4788024 IC50 33.0 nM
N#Cc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL1836717 IC50 35.0 nM
CC(=O)Nc1cccc(-c2cc3ncnc(SCC(=O)O)c3s2)c1 CHEMBL4747753 IC50 35.0 nM
CC(=O)c1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cn1 CHEMBL4740090 IC50 37.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(Cl)cc3)sc12 CHEMBL1836714 IC50 39.0 nM
CCOC(=O)c1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4783516 IC50 40.0 nM
CCc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4753625 IC50 41.0 nM
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL1287853 Kd 45.0 nM
O=C(O)CSc1ncnc2cc(-c3cccc(F)c3)sc12 CHEMBL4745018 IC50 49.0 nM
CC(C)Sc1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4740604 IC50 49.0 nM
CSc1cccc(-c2cc3ncnc(SCC(=O)O)c3s2)c1 CHEMBL4789685 IC50 49.0 nM
CC(C)c1ccc(-c2cc3ncnc(SCC(=O)O)c3s2)cc1 CHEMBL4748440 IC50 59.0 nM
O=C(O)CSc1ncnc2cc(-c3ccccc3F)sc12 CHEMBL4788886 IC50 60.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(C4CC4)cc3)sc12 CHEMBL4739879 IC50 62.0 nM
O=C(O)CSc1ncnc2cc(-c3cccs3)sc12 CHEMBL4792541 IC50 63.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(F)c(F)c3)sc12 CHEMBL4748561 IC50 74.0 nM
O=C1Nc2ccc(NC(=O)c3cc([N+](=O)[O-])cc([N+](=O)[O-])c3)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL3798563 IC50 77.0 nM
O=C(O)CSc1ncnc2cc(-c3cccc(N4CCOCC4)c3)sc12 CHEMBL4781408 IC50 83.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(Cl)c(Cl)c3)sc12 CHEMBL4755086 IC50 92.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 110.0 nM
O=C(O)CSc1ncnc2cc(-c3ccc(OCc4ccccc4)cc3)sc12 CHEMBL4794226 IC50 110.0 nM
COc1ccccc1-c1cc2ncnc(SCC(=O)O)c2s1 CHEMBL4752999 IC50 110.0 nM
O=C1Nc2ccc(NC(=O)c3ccccc3C(F)(F)F)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL3798680 IC50 120.0 nM
O=C1Nc2ccc(NC(=O)C3CCCCC3)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL3798579 IC50 120.0 nM
O=C(NCCCNc1ccnc(Nc2cccc(NC(=O)N3CCCC3)c2)n1)C1CCC1 CHEMBL5075360 IC50 161.0 nM
COc1ccc(-c2cnc3ncnc(NC(=O)C4CCCCC4)c3n2)cc1OC CHEMBL3334988 Kd 180.0 nM
O=C1Nc2ccc(NC(=O)c3ccccc3)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL3797732 IC50 200.0 nM
Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL604263 IC50 250.0 nM
COc1ccc2c(c1)C(=O)/C(=C/c1ccc(O)c(O)c1)O2 CHEMBL4087337 IC50 250.0 nM
Nc1c(-c2n[nH]c(=S)o2)sc2ccc(Cl)cc12 CHEMBL5401514 Kd 250.0 nM
O=C(O)CSc1ncnc2cc(-c3cccc(OC(F)(F)F)c3)sc12 CHEMBL4788686 IC50 280.0 nM
O=C1Nc2ccc(NC(=O)c3ccccc3F)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL3797817 IC50 290.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 320.0 nM
COc1ccc(C(=O)Nc2ccc3c(c2)/C(=C2/Nc4ccccc4/C2=N\O)C(=O)N3)cc1 CHEMBL3797582 IC50 330.0 nM
CCOc1cc(/C=C2\Oc3ccc(OC)cc3C2=O)ccc1O CHEMBL4105195 IC50 330.0 nM
O=C1Nc2ccccc2/C1=C/c1ccc[nH]1 CHEMBL86755 Kd 353.0 nM
COc1cc2c(-c3cnc(-c4ccc[nH]4)o3)c[nH]c2cc1Br CHEMBL4564337 Kd 390.0 nM
CCOc1ccc2c(c1)C(=O)/C(=C/c1ccc(O)c(OCC)c1)O2 CHEMBL4076100 IC50 410.0 nM
COc1ccc(-c2ccc3scc(NC(=O)C4CCCCC4)c3c2)cc1OC CHEMBL3334978 Kd 510.0 nM
COc1ccc(-c2cnc3snc(NC(=O)C4CCCCCC4)c3c2)cc1OC CHEMBL3334963 Kd 530.0 nM
O=C1Nc2ccc(F)cc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL1077291 IC50 620.0 nM
Cc1nn(CC(F)(F)F)cc1Nc1ncc(Br)c(NCc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL4446892 pKd 630.96 nM
COc1cc(-c2cnc3snc(NC(=O)C4CCCCC4)c3c2)ccc1N CHEMBL3334946 Kd 660.0 nM
COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1 CHEMBL502835 Kd 670.0 nM
CCOc1cc(/C=C2\Oc3ccc(OC(C)=O)cc3C2=O)ccc1O CHEMBL4099371 IC50 690.0 nM
O=C(/C=C/c1ccccc1)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL3798736 IC50 700.0 nM
O=C1Nc2ccccc2/C1=C1/Nc2ccccc2/C1=N\O CHEMBL216543 IC50 710.0 nM
COc1ccccc1-c1cc2c(SCC(=O)O)ncnc2s1 CHEMBL4793795 IC50 880.0 nM
O=C(O)CSc1ncnc2sc(-c3cc4ccccc4s3)cc12 CHEMBL4763392 Kd 910.0 nM
N[C@@H]1CCCN(c2c(/C=C3\SC(=O)NC3=O)cccc2-c2ccccc2)C1 CHEMBL2048872 Kd 930.0 nM
O=C(COc1cccc(Cl)c1)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 CHEMBL3799218 IC50 950.0 nM
COc1ccc(-c2ccc3onc(NC(=O)C4CCCCC4)c3c2)cc1OC CHEMBL3334983 Kd 960.0 nM
CCOc1cc(/C=C2\Oc3ccc(C)cc3C2=O)ccc1O CHEMBL4103220 IC50 960.0 nM
O=C1/C(=C/c2ccc(O)c(O)c2)Oc2ccc(O)cc21 CHEMBL4072438 IC50 990.0 nM