CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 0.22 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 5.8 nM
CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1N[C@H]1CC[C@H](CN(C)C)CC1 CHEMBL3688339 Kd apparent 21.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1 CHEMBL450786 Kd 43.0 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 Kd 44.0 nM
Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O CHEMBL477772 Kd 45.0 nM
CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL2334586 IC50 45.0 nM
CCCCCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3715872 IC50 50.0 nM
CCCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 CHEMBL3716788 IC50 50.0 nM
CCCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3717287 IC50 50.0 nM
CCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3717391 IC50 50.0 nM
CCCCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3716597 IC50 50.0 nM
CCCCOc1ccc(C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NC2CCCc3ccccc32)cc1 CHEMBL3715806 IC50 50.0 nM
O=C(NC(C(=O)NC1CCCc2ccccc21)c1cccnc1)c1ccc(-n2cncn2)cc1 CHEMBL3715987 IC50 50.0 nM
COc1ccc(/C=C/C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NC2CCCc3ccccc32)cc1OC CHEMBL3717452 IC50 50.0 nM
CCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 CHEMBL3716744 IC50 50.0 nM
CC(NC(=O)c1ccc(OCc2ccccc2)cc1)C(=O)NC1CCc2ccccc2C1 CHEMBL3716968 IC50 50.0 nM
Cc1cc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc(C)c1OCc1ccccc1 CHEMBL3718066 IC50 50.0 nM
CCCCOc1ccc(NC(=O)N[C@@H](COCc2ccccc2)C(=O)NCCc2ccccc2)cc1 CHEMBL3715589 IC50 50.0 nM
CCCCc1ccc(NC(=O)N2CCC[C@@]2(N)C(=O)NCc2ccc(Cl)c(Cl)c2)cc1 CHEMBL3719326 IC50 50.0 nM
COc1ccc2nc(NC(=O)CCCNC(=O)Cn3cnc4sc5c(c4c3=O)CCCC5)sc2c1 CHEMBL3717193 IC50 50.0 nM
CC(C)c1ccc(NC(=O)N2CCC[C@@]2(N)C(=O)NCc2ccc(Cl)c(Cl)c2)cc1 CHEMBL3717484 IC50 50.0 nM
O=C(CNC(=O)COc1ccc(Br)cc1)NCc1ccc(Cl)c(Cl)c1 CHEMBL3718166 IC50 50.0 nM
O=C(NC(C(=O)NC1CCCc2ccccc21)c1cccnc1)c1ccc(/N=N/c2ccccc2)cc1 CHEMBL3715005 IC50 50.0 nM
CCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3718736 IC50 50.0 nM
COc1cccc(OCC(=O)NCC(=O)NC2CCCc3ccccc32)c1 CHEMBL3718891 IC50 50.0 nM
COc1ccc(/C=C/C(=O)N[C@@H](COCc2ccccc2)C(=O)NC(c2ccccc2)c2ccccc2)cc1OC CHEMBL3717584 IC50 50.0 nM
CCCCCOc1ccc(C(=O)N[C@@H](CC(C)C)C(=O)NC2CCCc3ccccc32)cc1 CHEMBL3717111 IC50 50.0 nM
CCCCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 CHEMBL3716318 IC50 50.0 nM
CCOCCCn1c(=S)[nH]c2cc(C(=O)NCC3COc4ccccc4O3)ccc2c1=O CHEMBL3715362 IC50 50.0 nM
COc1ccc2nc(NC(=O)CNC(=O)Cn3cnc4sc(C)c(C)c4c3=O)sc2c1 CHEMBL3718473 IC50 50.0 nM
O=C(CNC(=O)c1ccc(OC(F)(F)F)cc1)NC1CCCc2ccccc21 CHEMBL3718965 IC50 50.0 nM
O=C(CNC(=O)c1ccc(Oc2ccccc2)cc1)NC1CCCc2ccccc21 CHEMBL3717468 IC50 50.0 nM
O=C(CNC(=O)c1ccc(C2CCCCC2)cc1)NC1CCCc2ccccc21 CHEMBL3719286 IC50 50.0 nM
O=C(CNC(=O)c1ccc(O)cc1)NC1CCCc2ccccc21 CHEMBL3716849 IC50 50.0 nM
COc1cc2cc(C(=O)NCC(=O)NC3CCCc4ccccc43)[nH]c2cc1OC CHEMBL3719051 IC50 50.0 nM
O=C(CNC(=O)c1ccc(-n2ccnc2)cc1)NC1CCCc2ccccc21 CHEMBL3718164 IC50 50.0 nM
O=C(CNC(=O)Nc1ccc(-c2ccccc2)cc1)NC1CCCc2ccccc21 CHEMBL3717373 IC50 50.0 nM
CCc1ccc(-c2ccc(C(=O)NCC(=O)NCc3ccccc3C)cc2)cc1 CHEMBL3715956 IC50 50.0 nM
O=C(CNC(=O)c1ccc(N2CCCCC2)cc1)NC1CCCc2ccccc21 CHEMBL3718940 IC50 50.0 nM
CCc1ccc(-c2ccc(C(=O)NCC(=O)NC(C)c3ccccc3)cc2)cc1 CHEMBL3715942 IC50 50.0 nM
CCc1ccc(-c2ccc(C(=O)NCC(=O)NCc3ccccc3C(F)(F)F)cc2)cc1 CHEMBL3716416 IC50 50.0 nM
O=C(CNC(=O)c1ccc2ncccc2c1)NC1CCCc2ccccc21 CHEMBL3717713 IC50 50.0 nM
CCc1ccc(-c2ccc(C(=O)NCC(=O)NC(CC)c3ccccc3)cc2)cc1 CHEMBL3716774 IC50 50.0 nM
O=C(CC(NC(=O)c1ccccc1)c1ccccc1)NCC(=O)Nc1nccs1 CHEMBL3716742 IC50 50.0 nM
O=C(NC1CCNCC1)c1n[nH]cc1NC(=O)c1c(Cl)cccc1Cl CHEMBL445813 Kd 57.0 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 CHEMBL572878 Kd 81.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 86.0 nM
CN(C)C[C@@H]1CCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCO1 CHEMBL91829 Kd 97.0 nM
CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CHEMBL428690 Kd 99.0 nM
Nc1nccc(-c2cc3c([nH]2)[C@@H](CCF)CNC3=O)n1 CHEMBL524266 IC50 126.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 210.0 nM
COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2)nc1N CHEMBL384304 Kd 210.0 nM
CN1C(=O)c2sccc2N(C)c2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc21 CHEMBL4554938 IC50 254.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL223360 Kd 260.0 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 293.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 310.0 nM
COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl CHEMBL288441 Kd 340.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 360.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 390.0 nM
C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL601719 Kd 490.0 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 Kd 490.0 nM
CCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3715050 IC50 500.0 nM
O=C(COc1ccc(OC(F)(F)F)cc1)NCC(=O)NC1CCCc2ccccc21 CHEMBL3719165 IC50 500.0 nM
CC(C)CC(NC(=O)c1ccc(-c2ccccc2)cc1)C(=O)NC1CCCc2ccccc21 CHEMBL3714849 IC50 500.0 nM
CC(C)(C)c1ccc(OCC(=O)NCC(=O)NC2CCCc3ccccc32)cc1 CHEMBL3716567 IC50 500.0 nM
O=C(COc1ccc(Cl)cc1)NCC(=O)NC1CCCc2ccccc21 CHEMBL3717761 IC50 500.0 nM
O=C(CNC(=O)c1ccc2ccccc2c1)NC1CCCc2ccccc21 CHEMBL3715041 IC50 500.0 nM
O=C(CNC(=O)c1ccc(N2CCOCC2)cc1)NC1CCCc2ccccc21 CHEMBL3718499 IC50 500.0 nM
O=C(CNC(=O)c1ccc2c(c1)CCCC2)NC1CCCc2ccccc21 CHEMBL3717552 IC50 500.0 nM
CCc1ccc(-c2ccc(C(=O)NCC(=O)NC3CN(C(=O)OC(C)(C)C)Cc4ccccc43)cc2)cc1 CHEMBL3717643 IC50 500.0 nM
CCc1ccc(-c2ccc(C(=O)NCC(=O)NC3CNCc4ccccc43)cc2)cc1 CHEMBL3717335 IC50 500.0 nM
N#CC[C@H](C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 CHEMBL1789941 Kd 590.0 nM
CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1 CHEMBL296468 Kd 620.0 nM
Cn1c(Nc2ccc(C(F)(F)F)cc2)nc2cc(Oc3ccnc(-c4ncc(C(F)(F)F)[nH]4)c3)ccc21 CHEMBL558752 Kd 720.0 nM
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 CHEMBL1908397 Kd 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM