CC(C)NCC(O)c1ccc(O)c(O)c1 CHEMBL434 EC50 4.9 nM
Cc1noc(C)c1Cn1cc(-n2c(=O)n(C)n(CCc3ccc(F)cc3)c2=O)cn1 CHEMBL3950223 IC50 10.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccc(F)cc3)C2=O)cn1 CHEMBL3976506 IC50 10.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cc(O)cc(O)c3)C(C)(C)C2=O)cn1 CHEMBL3898803 IC50 10.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@H](C)N(Cc3ccccc3)C2=O)cn1 CHEMBL3923956 IC50 10.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(F)c(O)c3)C(C)(C)C2=O)cn1 CHEMBL3939399 IC50 10.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@@H](C)N(Cc3ccccc3)C2=O)cn1 CHEMBL4112934 IC50 10.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3N)C2=O)cn1 CHEMBL3890262 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)C(C)N(Cc3ccccc3)C2=O)cn1 CHEMBL3979194 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(-n2c(=O)n(C)n(Cc3ccccc3)c2=O)cn1 CHEMBL3935648 IC50 20.0 nM
COCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 CHEMBL3939695 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@H](C)N(Cc3cccc(O)c3)C2=O)cn1 CHEMBL3933031 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@@H](C)N(Cc3cccc(O)c3)C2=O)cn1 CHEMBL4108527 IC50 20.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C23CC3)cc1O CHEMBL3902192 IC50 20.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C23CC3)cc1OC CHEMBL3939063 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)c3)C3(CC3)C2=O)cn1 CHEMBL3961116 IC50 20.0 nM
COc1cc(O)cc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3949830 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@@H]3Cc4ccc(O)cc4CN3C2=O)cn1 CHEMBL3964034 IC50 20.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(O)c3)C2=O)cn1 CHEMBL3924866 IC50 20.0 nM
CSc1ccccc1CN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O CHEMBL3911337 IC50 30.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)c3)C3(CCC3)C2=O)cn1 CHEMBL3970005 IC50 30.0 nM
COCc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C23CC3)c1 CHEMBL3911969 IC50 30.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@H]3Cc4ccc(O)cc4CN3C2=O)cn1 CHEMBL4113151 IC50 30.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)C3Cc4cc(O)ccc4CN3C2=O)cn1 CHEMBL3935598 IC50 30.0 nM
Cc1noc(C)c1Cn1cc(-n2c(=O)n(C)n(CCOc3ccccc3)c2=O)cn1 CHEMBL3945679 IC50 31.0 nM
Cc1noc(C)c1CN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O CHEMBL3941028 IC50 40.0 nM
COc1ccc(CCN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 CHEMBL3896760 IC50 40.0 nM
CCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 CHEMBL3948447 IC50 40.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@H](CO)N(Cc3cccc(O)c3)C2=O)cn1 CHEMBL3915586 IC50 40.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(C#N)cc3)C(C)(C)C2=O)cn1 CHEMBL3892490 IC50 40.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccc(O)cc3)C2=O)cn1 CHEMBL3948082 IC50 40.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccc(F)cc3)C2=O)cn1 CHEMBL3908407 IC50 50.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccc(C#N)cc3)C2=O)cn1 CHEMBL3979603 IC50 50.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)c3)C(C)(C)C2=O)cn1 CHEMBL3907822 IC50 50.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCOc3ccccc3)C2=O)cn1 CHEMBL3919358 IC50 60.0 nM
COc1ccccc1CN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O CHEMBL3979660 IC50 60.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(F)c3)C2=O)cn1 CHEMBL3900806 IC50 60.0 nM
Cc1ccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 CHEMBL3932834 IC50 60.0 nM
COc1ccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1OC CHEMBL3955923 IC50 60.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3cccc(F)c3)C2=O)cn1 CHEMBL3932036 IC50 60.0 nM
COCCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 CHEMBL3926125 IC50 60.0 nM
CCCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 CHEMBL3953765 IC50 60.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1O CHEMBL3981387 IC50 60.0 nM
COc1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3897715 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3O)C2=O)cn1 CHEMBL3896824 IC50 70.0 nM
COCCOc1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3921846 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3[N+](=O)[O-])C2=O)cn1 CHEMBL3983263 IC50 70.0 nM
COc1ccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 CHEMBL3967038 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccc4c(c3)OCO4)C2=O)cn1 CHEMBL3959229 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)c3)C3(CCCC3)C2=O)cn1 CHEMBL3893402 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(O)cc3)C(C)(C)C2=O)cn1 CHEMBL3921566 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccccc3O)C(C)(C)C2=O)cn1 CHEMBL3897007 IC50 70.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3F)C2=O)cn1 CHEMBL3965292 IC50 80.0 nM
Cc1noc(C)c1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3985403 IC50 80.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(F)cc3)C(C)(C)C2=O)cn1 CHEMBL3958788 IC50 80.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1OC CHEMBL3931283 IC50 80.0 nM
COc1ccccc1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3964716 IC50 80.0 nM
COc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3932779 IC50 80.0 nM
COc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)n1 CHEMBL3925053 IC50 80.0 nM
[C-]#[N+]c1ccccc1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3935390 IC50 80.0 nM
COC(=O)c1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3929225 IC50 90.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3)C2=O)cn1 CHEMBL3932026 IC50 90.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(C#N)c3)C(C)(C)C2=O)cn1 CHEMBL3903912 IC50 90.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cc3c(cc2Cl)OCCO3)cn1 CHEMBL3961992 IC50 100.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cc(Cl)c3c(c2)OCCO3)cn1 CHEMBL3892982 IC50 100.0 nM
COc1ccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1O CHEMBL3923778 IC50 100.0 nM
COCCOc1ccccc1CN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O CHEMBL3913870 IC50 100.0 nM
Cc1ccccc1CN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O CHEMBL3964777 IC50 100.0 nM
Cc1ccccc1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3894430 IC50 100.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)c3O)C(C)(C)C2=O)cn1 CHEMBL3926477 IC50 100.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3c(F)cccc3F)C(C)(C)C2=O)cn1 CHEMBL3898431 IC50 100.0 nM
CNC(=O)c1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3902340 IC50 100.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)c3)C(C)(CO)C2=O)cn1 CHEMBL3891080 IC50 100.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N[C@H](Cc3ccccc3)C2=O)cn1 CHEMBL4107363 IC50 110.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 CHEMBL3958274 IC50 110.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(CO)c3)C(C)(C)C2=O)cn1 CHEMBL3941755 IC50 110.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccccc3F)C(C)(C)C2=O)cn1 CHEMBL3978855 IC50 110.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N[C@@H](Cc3ccccc3)C2=O)cn1 CHEMBL3898921 IC50 120.0 nM
COc1ccc(CCN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 CHEMBL3921288 IC50 120.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(F)c3)C(C)(C)C2=O)cn1 CHEMBL3964698 IC50 120.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(O)c(O)c3)C(C)(C)C2=O)cn1 CHEMBL3940913 IC50 120.0 nM
Cc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3912916 IC50 120.0 nM
COc1cccc(CC2NC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3926266 IC50 130.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccccc3F)C2=O)cn1 CHEMBL3922377 IC50 130.0 nM
COCc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3918518 IC50 130.0 nM
COc1ccc(CCN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1OC CHEMBL3901905 IC50 130.0 nM
COc1ccccc1CCN1CC(=O)N(c2cnn(Cc3c(C)noc3C)c2)C1=O CHEMBL3900543 IC50 140.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccccc3)C2=O)cn1 CHEMBL3924802 IC50 140.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)C(Cc3ccccc3)N(C)C2=O)cn1 CHEMBL3946741 IC50 150.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(C(C)c3ccccc3)C(C)(C)C2=O)cn1 CHEMBL3951285 IC50 150.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCc3cccc(F)c3)C(C)(C)C2=O)cn1 CHEMBL3969518 IC50 150.0 nM
COc1cccc(CCN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3926104 IC50 160.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cc(C)n(C)n3)C(C)(C)C2=O)cn1 CHEMBL3926891 IC50 160.0 nM
COc1ccc(OC)c(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3945185 IC50 170.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(CCCc3ccccc3)C2=O)cn1 CHEMBL3934773 IC50 170.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)c3ccccc3C2=O)cn1 CHEMBL3898835 IC50 180.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(Cc3ccccc3)C2=O)cn1 CHEMBL3981376 IC50 180.0 nM
COc1cc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)ccc1F CHEMBL3945434 IC50 180.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)nc1 CHEMBL3890303 IC50 190.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccncc3)C(C)(C)C2=O)cn1 CHEMBL3927031 IC50 190.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3c(c2)OCO3)cn1 CHEMBL3917282 IC50 200.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cccc(C#N)c2)cn1 CHEMBL3957404 IC50 200.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3C(F)(F)F)C2=O)cn1 CHEMBL3954622 IC50 200.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(C=O)c3)C2=O)cn1 CHEMBL3925139 IC50 200.0 nM
Cc1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 CHEMBL3927927 IC50 200.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3cccc(Cl)c3)C2=O)cn1 CHEMBL3939226 IC50 200.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCc3ccccc3F)C(C)(C)C2=O)cn1 CHEMBL3950520 IC50 200.0 nM
COc1ccc(OC)c(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3922801 IC50 200.0 nM
COc1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(C(=O)O)cc2)cc1 CHEMBL3092287 IC50 200.0 nM
Cc1cc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)n(C)n1 CHEMBL4514970 IC50 200.0 nM
CCOc1cccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3904300 IC50 220.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(CCc3ccccc3)C2=O)cn1 CHEMBL3979675 IC50 220.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccnc3)C(C)(C)C2=O)cn1 CHEMBL3938926 IC50 220.0 nM
COC(=O)c1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3904739 IC50 220.0 nM
COc1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)n1 CHEMBL3929698 IC50 230.0 nM
Cc1cc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)n(C)n1 CHEMBL3924674 IC50 230.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCc3ccccc3)C(C)(C)C2=O)cn1 CHEMBL3978725 IC50 230.0 nM
COC(=O)c1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 CHEMBL3927388 IC50 230.0 nM
COc1ccccc1CCN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3967072 IC50 240.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cc(F)ccc3F)C(C)(C)C2=O)cn1 CHEMBL3923880 IC50 240.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)C2(c3ccccc3)CC2)cn1 CHEMBL3982707 IC50 250.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccccc3Cl)C2=O)cn1 CHEMBL3919276 IC50 250.0 nM
COc1cccc(CCN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3892375 IC50 250.0 nM
COc1ccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc1 CHEMBL3899757 IC50 260.0 nM
COc1ccc(CCN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1OC CHEMBL3904522 IC50 260.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCCc3ccccc3)C2=O)cn1 CHEMBL3938586 IC50 260.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccccn3)C(C)(C)C2=O)cn1 CHEMBL3935659 IC50 260.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc4c(c3)OCCO4)C(C)(C)C2=O)cn1 CHEMBL3963093 IC50 270.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)CC(C)c2ccccc2)cn1 CHEMBL3968408 IC50 280.0 nM
COc1cc(OC)cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3936756 IC50 280.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CC3CCCCC3)C2=O)cn1 CHEMBL3901756 IC50 280.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(OCCO)c3)C(C)(C)C2=O)cn1 CHEMBL3948947 IC50 280.0 nM
COCc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 CHEMBL3956109 IC50 280.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cccc3c2OCO3)cn1 CHEMBL3911857 IC50 300.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cc3c(cc2Br)OCCO3)cn1 CHEMBL3953071 IC50 300.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cc(C)n(C)n3)C2=O)cn1 CHEMBL3895754 IC50 300.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(CO)c3)C2=O)cn1 CHEMBL3950626 IC50 300.0 nM
COc1cc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc(OC)c1 CHEMBL3973161 IC50 300.0 nM
COc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1OC CHEMBL3974063 IC50 300.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)C(C)c2ccccc2)cn1 CHEMBL3930844 IC50 300.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3[nH]ccc3c2)cn1 CHEMBL4452065 IC50 300.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(CC3CCCC3)C2=O)cn1 CHEMBL3957721 IC50 310.0 nM
COc1cccc(F)c1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3921282 IC50 310.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(F)c3F)C(C)(C)C2=O)cn1 CHEMBL3949113 IC50 310.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccccc3)C(C)(C)C2=O)cn1 CHEMBL3926724 IC50 320.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(Cc3ccc(O)cc3)C2=O)cn1 CHEMBL3926716 IC50 330.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1F CHEMBL3957733 IC50 330.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCc3ccc(F)cc3)C(C)(C)C2=O)cn1 CHEMBL3902167 IC50 330.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N/C(=C\c3ccccc3)C2=O)cn1 CHEMBL3948003 IC50 340.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCOc3ccccc3)C(C)(C)C2=O)cn1 CHEMBL3961048 IC50 350.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(CO)cc3)C(C)(C)C2=O)cn1 CHEMBL3946823 IC50 360.0 nM
COc1cccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3939850 IC50 390.0 nM
COc1ccccc1C(=O)Nc1cnn(Cc2c(C)noc2C)c1 CHEMBL3908801 IC50 390.0 nM
COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc(OC)c1O CHEMBL3936248 IC50 390.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3c(c2)OCCO3)cn1 CHEMBL3891877 IC50 400.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3[S+](C)[O-])C2=O)cn1 CHEMBL3894555 IC50 400.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccn(C)n3)C2=O)cn1 CHEMBL3898870 IC50 400.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCc3cc(F)cc(F)c3)C(C)(C)C2=O)cn1 CHEMBL3930146 IC50 400.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)CCc2ccccc2)cn1 CHEMBL3918801 IC50 400.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cccc(O)c2)cn1 CHEMBL4469393 IC50 400.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)[C@@H](C)c2ccccc2)cn1 CHEMBL3904507 IC50 410.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccc(O)cc3)C2=O)cn1 CHEMBL3932517 IC50 410.0 nM
CCCCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 CHEMBL3962515 IC50 410.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccn(C)n3)C(C)(C)C2=O)cn1 CHEMBL3941993 IC50 420.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(O)n3)C(C)(C)C2=O)cn1 CHEMBL3914005 IC50 440.0 nM
COc1cc(CC(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc(OC)c1O CHEMBL3902860 IC50 460.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3cccc(C(=O)O)c3)C(C)(C)C2=O)cn1 CHEMBL3963907 IC50 460.0 nM
COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)ccc1O CHEMBL3945644 IC50 480.0 nM
CCC(C(=O)Nc1cnn(Cc2c(C)noc2C)c1)c1ccccc1 CHEMBL3971132 IC50 500.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3C#N)C2=O)cn1 CHEMBL3899833 IC50 500.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc(O)cc2)cn1 CHEMBL4567380 IC50 500.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(Cc3ccc(O)c(O)c3)C2=O)cn1 CHEMBL3949101 IC50 510.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)Cc2ccccc2)cn1 CHEMBL3908324 IC50 530.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)C(C)(C)c2ccccc2)cn1 CHEMBL3941536 IC50 530.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(F)cc3F)C(C)(C)C2=O)cn1 CHEMBL3919495 IC50 530.0 nM
COC(=O)COc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3956008 IC50 530.0 nM
COc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1C CHEMBL3928400 IC50 540.0 nM
COc1ccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc1OC CHEMBL3921262 IC50 560.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCO)C(C)(C)C2=O)cn1 CHEMBL3967116 IC50 560.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccccn2)cn1 CHEMBL3911209 IC50 570.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc[nH]2)cn1 CHEMBL3963524 IC50 570.0 nM
Cc1cccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3912902 IC50 570.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(C)C2=O)cn1 CHEMBL3927302 IC50 580.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(CCCc3ccccc3)C(C)(C)C2=O)cn1 CHEMBL3940950 IC50 580.0 nM
COCCN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C CHEMBL3899299 IC50 590.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cccc3c2OCCO3)cn1 CHEMBL3893359 IC50 600.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3[nH]cnc3c2)cn1 CHEMBL3977982 IC50 600.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3[nH]nnc3c2)cn1 CHEMBL3907422 IC50 600.0 nM
Cc1noc(C)c1Cn1cc(-n2c(=O)n(C)n(C)c2=O)cn1 CHEMBL3924285 IC50 600.0 nM
COc1cccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1OC CHEMBL3890306 IC50 610.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)[C@H](C(C)C)N(Cc3cccc(O)c3)C2=O)cn1 CHEMBL3954679 IC50 650.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccn3)C2=O)cn1 CHEMBL3912134 IC50 680.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)/C=C/c2ccccc2)cn1 CHEMBL3894331 IC50 700.0 nM
Cc1nc2ccc(C(=O)Nc3cnn(Cc4c(C)noc4C)c3)cc2o1 CHEMBL3896707 IC50 700.0 nM
COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc2c1OCO2 CHEMBL3890651 IC50 700.0 nM
COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc2c1OCCO2 CHEMBL3943473 IC50 700.0 nM
COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc2c1OC(C)O2 CHEMBL3976167 IC50 700.0 nM
COc1cc2c(cc1C(=O)Nc1cnn(Cc3c(C)noc3C)c1)OCCO2 CHEMBL3919038 IC50 700.0 nM
COc1cccc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)n1 CHEMBL4447100 IC50 700.0 nM
COCCOc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1 CHEMBL3949716 IC50 710.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cccc(S(C)(=O)=O)c2)cn1 CHEMBL3921888 IC50 720.0 nM
Cc1c[nH]c(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3986303 IC50 720.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(CO)n3)C2=O)cn1 CHEMBL3915301 IC50 720.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)CC2CCCCC2)cn1 CHEMBL3922360 IC50 730.0 nM
Cc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 CHEMBL3910086 IC50 740.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(CC(=O)Nc3ccccc3)C2=O)cn1 CHEMBL3967574 IC50 750.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(COCc3ccccc3)C2=O)cn1 CHEMBL3958764 IC50 760.0 nM
Cc1noc(C)c1Cn1cc(NC(=S)Nc2cccc(C#N)c2)cn1 CHEMBL3947337 IC50 783.0 nM
COc1cccc(CC(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1OC CHEMBL3899263 IC50 800.0 nM
CCc1nc2cc(C(=O)Nc3cnn(Cc4c(C)noc4C)c3)ccc2o1 CHEMBL3894433 IC50 800.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccc3nccnc3c2)cn1 CHEMBL3965845 IC50 800.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)N(C)C(C)(C)C2=O)cn1 CHEMBL3904024 IC50 800.0 nM
Cc1noc(C)c1Cn1cc(-n2c(=O)n(Cc3ccccc3)n(Cc3ccccc3)c2=O)cn1 CHEMBL3985068 IC50 800.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)CCCc2ccccc2)cn1 CHEMBL3890731 IC50 800.0 nM
COc1cncc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL4456506 IC50 800.0 nM
Cc1cccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)c1F CHEMBL3941508 IC50 810.0 nM
CC(=O)OC(C(=O)Nc1cnn(Cc2c(C)noc2C)c1)c1ccccc1 CHEMBL3946779 IC50 830.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)C23CC4CC(CC(C4)C2)C3)cn1 CHEMBL3931276 IC50 880.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2cccc(Cl)c2)cn1 CHEMBL3977534 IC50 900.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(CNC(=O)OC(C)(C)C)c3)C2=O)cn1 CHEMBL3947381 IC50 900.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CNC2=O)cn1 CHEMBL3930312 IC50 900.0 nM
COc1cc(CC(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc(OC)c1 CHEMBL3927291 IC50 960.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)C(CO)c2ccccc2)cn1 CHEMBL3926634 IC50 960.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(CC3CCCCC3)C2=O)cn1 CHEMBL3953908 IC50 960.0 nM
COc1ccc(O)c(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)c1 CHEMBL3982791 IC50 980.0 nM
COc1ccc(CC(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc1 CHEMBL3900772 IC50 990.0 nM
Cc1nc2cc(C(=O)Nc3cnn(Cc4c(C)noc4C)c3)ccc2[nH]1 CHEMBL3903394 IC50 1000.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(C#N)c3)C2=O)cn1 CHEMBL3919109 IC50 1000.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)NC(CC(C)C)C2=O)cn1 CHEMBL3921270 IC50 1000.0 nM
COc1ccnc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1OC CHEMBL3983912 IC50 1000.0 nM
Cc1noc(C)c1Cn1cc(N2CCN(Cc3ccccc3)C2=O)cn1 CHEMBL4530528 IC50 1000.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)NCc2ccccc2)cn1 CHEMBL4526144 IC50 1000.0 nM
Cc1noc(C)c1Cn1cc(NC(=O)c2ccccc2O)cn1 CHEMBL4588973 IC50 1000.0 nM
Cc1noc(C)c1Cn1cc(N2C(=O)CN(CC3CCCO3)C2=O)cn1 CHEMBL3910649 IC50 1000.0 nM