O=C(O)CCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL26820 IC50 0.89 nM
O=C(O)CCCC/C=C(/c1ccccc1)c1cccnc1 CHEMBL28196 IC50 0.9 nM
Cc1ccncc1CCCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCC(=O)O CHEMBL137402 IC50 1.0 nM
Cc1ccc(S(=O)(=O)NCCCCC(CCCc2cccnc2)CCC(=O)O)cc1 CHEMBL435590 IC50 1.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(F)cc1)C2 CHEMBL338420 IC50 1.0 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(F)cc1)CCCc1cccnc1 CHEMBL136762 IC50 1.0 nM
CCOC(=O)CCCCO/N=C(\c1ccccc1)c1cccnc1 CHEMBL165575 IC50 1.0 nM
CCOC(=O)CCCCO/N=C(/c1ccccc1)c1cccnc1 CHEMBL117233 IC50 1.0 nM
CCOC(=O)CCCCO/N=C(\c1cccnc1)c1cccc(NC(=O)c2ccn3c2CSC3c2cccnc2)c1 CHEMBL116975 IC50 1.2 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc2ccccc2c1)CCCc1cccnc1 CHEMBL136738 IC50 1.5 nM
Cc1nc2cnccc2n1Cc1ccc(S(=O)(=O)NCc2cccc(/C(=N\OCCCCC(=O)O)c3cccnc3)c2)cc1 CHEMBL117816 IC50 1.8 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL65414 IC50 2.0 nM
O=C(O)CCCCC(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL339269 IC50 2.0 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(C(F)(F)F)cc1)CCCc1cccnc1 CHEMBL139372 IC50 2.0 nM
O=C(O)CSC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL341686 IC50 2.0 nM
Cn1c(-c2cccnc2)c(CCCCCC(=O)O)c2cc(Cl)ccc21 CHEMBL301550 IC50 2.0 nM
O=C([O-])CCC/C=C\C[C@H]1[C@@H]2CCC(C2)[C@@H]1NS(=O)(=O)c1ccccc1 CHEMBL53346 IC50 2.3 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCOc1cccnc1 CHEMBL63904 IC50 2.6 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCOc3ccccc3)co2)cc1)c1cccnc1 CHEMBL151083 IC50 2.6 nM
COc1ccc(CCCNC(=O)c2coc(-c3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)n2)cc1 CHEMBL151091 IC50 2.7 nM
O=C(O)CCCCCc1cccc2cncn12 CHEMBL48092 IC50 3.0 nM
O=C(O)CCCCO/N=C(/c1cccnc1)c1cccc(C(F)(F)F)c1 CHEMBL280728 IC50 3.0 nM
O=C(O)c1ccc(OCCn2ccnc2)cc1 CHEMBL267473 IC50 3.0 nM
COc1ccc(S(=O)(=O)NCCCCC(CCCc2cccnc2)CCC(=O)O)cc1 CHEMBL344457 IC50 3.0 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1ccc[n+]([O-])c1 CHEMBL136371 IC50 3.0 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCn1ccnc1 CHEMBL134580 IC50 3.0 nM
CC(CC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1)C(=O)O CHEMBL136934 IC50 3.0 nM
C/C(=C/c1ccc(Cc2cccnc2)cc1)C(=O)O CHEMBL543256 IC50 3.0 nM
CC(C)(C)/N=C(\Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1)NS(=O)(=O)c1ccccc1 CHEMBL21954 IC50 3.0 nM
N#CN/C(=N/C1CCCCC1)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL282884 IC50 3.0 nM
N#CN/C(=N/C1CCCC1)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL21639 IC50 3.0 nM
N#CN/C(=N/C12CC3CC(CC(C3)C1)C2)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL21852 IC50 3.0 nM
CC(C)CC/N=C(/NC#N)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL416374 IC50 3.0 nM
O=C(O)CC[C@H](CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCOc1cccnc1 CHEMBL68058 IC50 3.5 nM
CCOC(=O)CCCCO/N=C(\c1ccc(NC(=O)c2ccn3c2CSC3c2cccnc2)cc1)c1cccnc1 CHEMBL263227 IC50 3.6 nM
O=C(O)c1ccc2c(c1)C(SCc1cccnc1)c1ccccc1CO2 CHEMBL40736 IC50 4.0 nM
CCN(CCc1ccc(/C(=C\CCCC(=O)O)c2cccnc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL130470 IC50 4.0 nM
[N-]=[N+]=Nc1ccc(S(=O)(=O)NCCCCC(CCCc2cccnc2)CCC(=O)O)cc1 CHEMBL137505 IC50 4.0 nM
CS(=O)(=O)c1ccc(S(=O)(=O)NCCCCC(CCCc2cccnc2)CCC(=O)O)cc1 CHEMBL138328 IC50 4.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL127380 IC50 4.0 nM
O=C(O)CCC/C=C(\c1ccc(CCN(CCN2CCOCC2)S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL338419 IC50 4.0 nM
CC(C)(C)/N=C(\NC#N)Nc1cccc(/C(=C/CCCC(=O)O)c2cccnc2)c1 CHEMBL7718 IC50 4.0 nM
O=C(O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL277689 IC50 4.0 nM
Cn1c(CCNS(=O)(=O)c2ccc(F)cc2)ccc1/C(=C\CCCC(=O)O)c1cccnc1 CHEMBL339812 IC50 4.0 nM
O=C(O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(F)cc2)cc1)c1cccnc1 CHEMBL341094 IC50 4.0 nM
O=C(O)c1cccc(/C=C(\c2ccc(CCNS(=O)(=O)c3ccc(Cl)cc3)cc2)c2cccnc2)c1 CHEMBL126334 IC50 4.0 nM
Cn1c(-c2cccnc2)c(CCCCCC(=O)NCCCC[C@H](N[C@@H]2CCc3ccccc3N(CC(=O)[O-])C2=O)C(=O)[O-])c2cc(Cl)ccc21 CHEMBL301130 IC50 4.0 nM
C/C(=C\c1ccc(Cn2ccnc2)cc1)C(=O)O CHEMBL543726 IC50 4.0 nM
C/C(=C\c1cccc(Cn2ccnc2)c1)C(=O)O CHEMBL542300 IC50 4.0 nM
O=C(O)C(CCCCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCCCc1cccnc1 CHEMBL136904 IC50 4.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(N/C(=N\C2CCCC2)NC(=O)c2ccccc2)c1 CHEMBL21303 IC50 4.0 nM
CC(C)(C)N/C(=N\C#N)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL281398 IC50 4.0 nM
CC(C)(C)NC(=O)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL21647 IC50 4.0 nM
C/C(=C\c1ccc(Cc2cccnc2)cc1)C(=O)[O-] CHEMBL11811 IC50 4.3 nM
O=C(O)CC/C=C\CC[C@H]1[C@@H](OCc2ccc(-c3ccccc3)cc2)CO[C@@H]1c1cccnc1 CHEMBL63040 IC50 4.3 nM
O=C(O)CC[C@@H](CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL65187 IC50 4.5 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CNS(=O)(=O)c2ccc(Cn3c(C)nc4cnccc43)cc2)c1 CHEMBL117018 IC50 4.7 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CNS(=O)(=O)c2ccc(Cn3c(C)nc4ccccc43)cc2)c1 CHEMBL5270846 IC50 4.7 nM
O=C(O)/C=C/CCCc1cccc2cncn12 CHEMBL294924 IC50 4.8 nM
O=C(O)CCn1c(C2CC2)c(Cn2ccnc2)c2ccccc21 CHEMBL114723 IC50 4.9 nM
O=C(O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccccc2)cc1)c1cccnc1 CHEMBL126761 IC50 5.0 nM
CCCCS(=O)(=O)NCCc1ccc(/C(=C\CCCC(=O)O)c2cccnc2)cc1 CHEMBL415519 IC50 5.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CNS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL127683 IC50 5.0 nM
COc1ccc(S(=O)(=O)NCCc2ccc(/C(=C\CCCC(=O)O)c3cccnc3)cc2)cc1OC CHEMBL129635 IC50 5.0 nM
O=C(O)CCC/C=C(\c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL339568 IC50 5.0 nM
NC(=O)CN(CCc1ccc(/C(=C\CCCC(=O)O)c2cccnc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL126196 IC50 5.0 nM
O=S(=O)(NCCCCC(CCCc1cccnc1)CCC1N=NN=N1)c1ccc(Cl)cc1 CHEMBL138743 IC50 5.0 nM
O=C(O)CCC/C=C(\c1ccc(CCNS(=O)(=O)Cc2ccccc2)cc1)c1cccnc1 CHEMBL127357 IC50 5.0 nM
Cc1ccc(S(=O)(=O)NCCc2ccc(/C(=C\CCCC(=O)O)c3cccnc3)cc2)cc1 CHEMBL129734 IC50 5.0 nM
O=C(O)CC[C@H](CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL64005 IC50 5.0 nM
COc1ccc(S(=O)(=O)NCCc2ccc(/C(=C\CCCC(=O)O)c3cccnc3)cc2)cc1 CHEMBL338241 IC50 5.0 nM
O=C(O)c1cc2cc(Cn3ccnc3)ccc2[nH]1 CHEMBL44445 IC50 5.0 nM
COc1cc(Cn2ccnc2)cc2sc(C(=O)O)cc12 CHEMBL47021 IC50 5.0 nM
O=C(O)/C(Br)=C/c1ccc(Cc2cccnc2)cc1 CHEMBL536798 IC50 5.0 nM
O=C(O)c1ccc(CCCn2ccnc2)cc1 CHEMBL554568 IC50 5.0 nM
CC(C)(C)/N=C(\NC#N)Nc1cccc(/C(=N\OCCCCC(=O)O)c2cccnc2)c1 CHEMBL22023 IC50 5.0 nM
CC(C)(C)/N=C(\NC#N)Nc1cccc(/C(=C\CCCCCC(=O)O)c2cccnc2)c1 CHEMBL21476 IC50 5.0 nM
Cc1c(C(=O)O)sc2cc(Cn3ccnc3)ccc12 CHEMBL42462 IC50 5.2 nM
O=C(O)CCCCCCc1cccc2cncn12 CHEMBL45685 IC50 5.2 nM
CCOC(=O)CCCCO/N=C(\c1cccnc1)c1cccc(CNS(=O)(=O)c2ccc(Cn3c(C)nc4cnccc43)cc2)c1 CHEMBL2111765 IC50 5.8 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)N[C@@H]3C[C@H]3c3ccccc3)co2)cc1)c1cccnc1 CHEMBL151519 IC50 5.9 nM
O=C(O)CCCCO/N=C(\c1cccc(C(F)(F)F)c1)c1cnccn1 CHEMBL129867 IC50 6.0 nM
O=C(O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1)c1cccnc1 CHEMBL338360 IC50 6.0 nM
O=C(O)C1=Cc2sc(Cn3ccnc3)cc2CC1 CHEMBL22542 IC50 6.0 nM
CC(C)(C)/N=C(\NC#N)Nc1cccc(/C(=C\CCCCC(=O)O)c2cccnc2)c1 CHEMBL21478 IC50 6.0 nM
O=C(O)CCC/C=C(\c1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL340396 IC50 7.0 nM
O=C([O-])CCC(C/C=C/c1cccnc1)CCCCNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL136880 IC50 7.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL128022 IC50 7.0 nM
O=C(O)CC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL345105 IC50 7.0 nM
CC/C(=C\c1ccc(Cc2cccnc2)cc1)C(=O)O CHEMBL557386 IC50 7.0 nM
O=C(O)CCCCCC[C@H]1C2CCC(C2)[C@H]1c1cccnc1 CHEMBL301280 IC50 7.0 nM
O=C(O)Cc1cc(CCCNS(=O)(=O)c2ccc(Cl)cc2)cc(CCc2cccnc2)c1 CHEMBL295121 IC50 7.0 nM
O=C(O)c1sc2cc(Cn3ccnc3)ccc2c1Cl CHEMBL42461 IC50 7.4 nM
O=C(O)CCC/C=C(/c1cccnc1)c1ccc2c(c1)CCC(NS(=O)(=O)c1ccc(Cl)cc1)C2 CHEMBL126577 IC50 8.0 nM
CC(C)c1c(Cn2ccnc2)c2ccccc2n1CCC(=O)O CHEMBL114672 IC50 8.2 nM
CCn1cc(Cn2ccnc2)c2ccccc21 CHEMBL115899 IC50 8.4 nM
CCOP(=O)(O)CCCCn1c(-c2cccnc2)c(C)c2ccccc21 CHEMBL544493 IC50 9.0 nM
CC(C)(CCCC#CCn1ccnc1)C(=O)O CHEMBL555625 IC50 9.0 nM
CNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 CHEMBL105139 IC50 9.0 nM
COC(=O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(CCc2cccnc2)c1 CHEMBL43745 IC50 9.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCc3ccccc3)co2)cc1)c1cccnc1 CHEMBL150563 IC50 9.4 nM
O=C(O)CC/C=C\CC[C@@H]1[C@@H](c2cccnc2)SC[C@H]1OCc1ccc(-c2ccccc2)cc1 CHEMBL292331 IC50 10.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](CCCCCOc2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL297385 IC50 10.0 nM
CC(C)(CCCCCc1ccc(/C(=C\CCCCC(=O)O)c2cccnc2)cc1)[C@H]1OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c2ccccc2O)O1 CHEMBL291167 IC50 10.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(COc3cccc(/C(=C\CCCCC(=O)O)c4cccnc4)c3)cc2)O[C@@H]1c1ccccc1O CHEMBL42677 IC50 10.0 nM
O=C(O)/C=C/C(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL134686 IC50 10.0 nM
Cn1c(-c2cccnc2)c(CCCCCC(=O)NCCNCCCC[C@H](N[C@H]2CCc3ccccc3N(CC(=O)[O-])C2=O)C(=O)[O-])c2cc(Cl)ccc21 CHEMBL55763 IC50 10.0 nM
O=C(O)/C=C/c1ccc(Cc2cccnc2)cc1 CHEMBL537261 IC50 10.0 nM
Cc1c(-c2cccnc2)n(CCCCC(=O)O)c2ccccc12 CHEMBL415946 IC50 10.0 nM
CCNc1nc2c(Cc3cccnc3)c(C)c(O)c(C)c2s1 CHEMBL3217077 IC50 10.0 nM
CC(Cn1ccnc1)Cn1c(=O)[nH]c2cc(Cl)ccc2c1=O CHEMBL544065 IC50 10.0 nM
O=C(O)CCn1cc(Cn2ccnc2)c2ccc(C(F)(F)F)cc21 CHEMBL116980 IC50 10.0 nM
O=C(O)CC/C=C\CC[C@H]1[C@@H](OCc2ccc(-c3ccccc3)cc2)CS[C@@H]1c1cccnc1 CHEMBL62834 IC50 11.0 nM
O=C(O)/C=C/c1ccc(Cn2ccnc2)cc1 CHEMBL542549 IC50 11.0 nM
c1cc(CCCCc2nnn[nH]2)n2cncc2c1 CHEMBL543077 IC50 11.0 nM
N#CN/C(=N/Cc1ccccc1)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL440096 IC50 11.0 nM
CC(OCCCNC(=O)c1coc(-c2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)n1)C1CCCCC1 CHEMBL150206 IC50 11.5 nM
O=C(O)c1ccc2oc(Cn3ccnc3)cc2c1 CHEMBL46866 IC50 12.0 nM
Cc1c(-c2cccnc2)n(CCCCCCCC(=O)O)c2ccccc12 CHEMBL52948 IC50 12.0 nM
C/C(=C\c1ccc(Cc2cccnc2)s1)C(=O)O CHEMBL543496 IC50 12.0 nM
CC(C)(Cc1ccccc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL346590 IC50 12.0 nM
O=C(O)CCCCO/N=C(\c1cccnc1)c1cccc(CN2CCN(C(=O)C3CSC(c4cccnc4)N3)CC2)c1 CHEMBL324533 IC50 12.0 nM
O=C(O)CCn1cc(Cn2ccnc2)c2cc(Br)ccc21 CHEMBL117459 IC50 12.0 nM
O=C(O)CC[C@@H](CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCOc1cccnc1 CHEMBL302970 IC50 13.0 nM
O=C(O)c1ccc2c(c1)/C(=C\Cc1cccnc1)c1ccccc1CO2 CHEMBL40937 IC50 14.0 nM
O=C(O)c1ccc(OCCn2ccnc2)cc1 CHEMBL537708 IC50 14.0 nM
O=C(O)CCCCC(CCNS(=O)(=O)c1ccc(Cl)cc1)Cc1cccnc1 CHEMBL337331 IC50 14.0 nM
Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1ccnc1 CHEMBL104 IC50 14.0 nM
Cc1c(Cn2ccnc2)n(CCCNS(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)O)cc12 CHEMBL105856 IC50 15.0 nM
O=C(O)CCCCCCc1cnccc1CCCNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL297561 IC50 15.0 nM
CC(C)c1[nH]c2ccccc2c1Cn1ccnc1 CHEMBL284356 IC50 15.0 nM
O=C(O)c1ccc2sc(Cn3ccnc3)cc2c1 CHEMBL46912 IC50 15.0 nM
c1cn(CCOc2ccc(-c3nn[nH]n3)cc2)cn1 CHEMBL33632 IC50 15.0 nM
CN(CCc1ccc(/C(=C\CCCC(=O)O)c2cccnc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL129355 IC50 15.0 nM
CC(C)(Oc1ccc(F)cc1C#N)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL161063 IC50 15.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)ccc1CCc1cccnc1 CHEMBL297806 IC50 15.0 nM
O=C(O)CCCCO/N=C(/c1ccnnc1)c1cccc(C(F)(F)F)c1 CHEMBL132385 IC50 16.0 nM
O=C(O)/C=C\CCCCCn1ccnc1 CHEMBL14771 IC50 16.0 nM
C=C(CCCCCCn1ccnc1)C(=O)O CHEMBL537260 IC50 16.0 nM
Cc1c(Cn2ccnc2)sc2ccc(C(=O)O)cc12 CHEMBL43141 IC50 17.0 nM
Cc1c(Cn2ccnc2)sc2cc(C(=O)O)ccc12 CHEMBL47164 IC50 18.0 nM
O=C(O)COC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL343535 IC50 18.0 nM
O=C(O)c1cc2ccc(Cn3ccnc3)cc2s1 CHEMBL42386 IC50 18.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccccc2)cc(Cn2ccnc2)c1 CHEMBL117752 IC50 18.0 nM
Cc1ccc(OC(C)(C)[C@H]2OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c3cncs3)O2)c([N+](=O)[O-])c1 CHEMBL277167 IC50 18.0 nM
CC(C)(CCC/C=C(/c1cccnc1)c1cccs1)C(=O)O CHEMBL98477 IC50 18.0 nM
CNCCN(CCCC[C@H](N[C@H]1CCc2ccccc2N(CC(=O)[O-])C1=O)C(=O)[O-])C(=O)CCCCCc1c(-c2cccnc2)n(C)c2ccc(Cl)cc12 CHEMBL53709 IC50 18.0 nM
C/C(=C\C(=O)O)c1ccc(Cc2cccnc2)c(C)c1 CHEMBL542788 IC50 18.0 nM
Cc1cc(C)c(S(=O)(=O)NCCc2ccc(/C(=C\CCCC(=O)O)c3cccnc3)cc2)c(C)c1 CHEMBL338588 IC50 19.0 nM
O=C(O)c1csc2cc(Cn3ccnc3)ccc12 CHEMBL42795 IC50 19.0 nM
Cc1ccc(OC(C)(C)[C@H]2OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c3cccnc3)O2)c([N+](=O)[O-])c1 CHEMBL279847 IC50 19.0 nM
Cc1c(Cn2ccnc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc2n1CCC(=O)O CHEMBL45075 IC50 19.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1ccc2ccccc2c1 CHEMBL320009 IC50 19.0 nM
Cc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c([N+](=O)[O-])c1 CHEMBL352668 IC50 19.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1cccc(-c2nc(C(=O)NCCCCC3CCCCC3)co2)c1 CHEMBL293764 IC50 19.0 nM
c1cc(CCCCCc2nnn[nH]2)n2cncc2c1 CHEMBL544722 IC50 19.0 nM
C/C(=C\CCCCCc1cccc2cncn12)C(=O)O CHEMBL43731 IC50 19.0 nM
O=C(O)CCn1cc(Cn2ccnc2)c2ccccc21 CHEMBL269619 IC50 19.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(I)cc2)c1 CHEMBL161422 Log IC50 19.95 nM
COc1ccc2c(=O)n3cc(C(=O)NCCCCc4cccnc4)ccc3nc2c1 CHEMBL56418 IC50 20.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3cc(Cl)ccc3c(=O)n2c1 CHEMBL57489 IC50 20.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3ccccc3c(=O)n2c1 CHEMBL60625 IC50 20.0 nM
Cc1c(Cn2ccnc2)n(CCNS(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)O)cc12 CHEMBL102360 IC50 20.0 nM
CC(C)(CC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1)C(=O)O CHEMBL134365 IC50 20.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(COc3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)cc2)O[C@@H]1c1ccccc1O CHEMBL40425 IC50 20.0 nM
O=C(O)C1CCc2cc(Cn3ccnc3)sc2C1 CHEMBL23942 IC50 20.0 nM
O=C(O)c1cc2ccc(Cn3ccnc3)cc2o1 CHEMBL42609 IC50 20.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(F)cc2)cc(Cc2cccnc2)c1 CHEMBL115387 IC50 20.0 nM
Cn1c(-c2cccnc2)c(CCCCCC(=O)N(CCO)CCCC[C@H](N[C@H]2CCc3ccccc3N(CC(=O)O)C2=O)C(=O)O)c2cc(Cl)ccc21 CHEMBL299309 IC50 20.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccs1 CHEMBL98715 IC50 20.0 nM
Cc1c(-c2cccnc2)n(CCCCCCCC(=O)O[C@@H]2C[C@H](N[C@@H](CCc3ccccc3)C(=O)O)C(=O)N(CC(=O)O)c3ccccc32)c2ccccc12 CHEMBL296151 IC50 20.0 nM
Cc1c(-c2cccnc2)n(CCCCP(=O)(O)OC2CCc3ccccc3N(CC(=O)O)C2=O)c2ccccc12 CHEMBL54520 IC50 20.0 nM
CC(Cc1ccc(Cc2cccnc2)cc1)C(=O)O CHEMBL537926 IC50 20.0 nM
Cn1c(-c2cccnc2)c(CCCCCC(=O)N2CCC(NCCCC[C@H](N[C@@H]3CCc4ccccc4N(CC(=O)[O-])C3=O)C(=O)[O-])CC2)c2cc(Cl)ccc21 CHEMBL300130 IC50 20.0 nM
CC(C)(Oc1ccc(F)cc1[N+](=O)[O-])C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159243 IC50 20.0 nM
O=C(O)CCCC(CCCNS(=O)(=O)c1ccc(Cl)cc1)CCc1cccnc1 CHEMBL136845 IC50 20.0 nM
O=C(CCCCCc1cccc2cncn12)NO CHEMBL45632 IC50 20.0 nM
N#Cc1ccc([C@H]2OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c3cccnc3)O2)cc1 CHEMBL96727 IC50 20.0 nM
O=S(=O)(NCCc1ccc(/C(=C\CCCc2nnn[nH]2)c2cccnc2)cc1)c1ccc(Cl)cc1 CHEMBL126185 IC50 21.0 nM
O=C(O)CC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL419774 IC50 21.0 nM
O=C(O)CCC/C=C(\c1ccc(CCNC(=O)Cc2ccccc2)cc1)c1cccnc1 CHEMBL338334 IC50 21.0 nM
O=C(O)c1cc2cc(Cn3ccnc3)ccc2s1 CHEMBL290046 IC50 21.0 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CCCCN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL352120 IC50 21.0 nM
CC(C)(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL432014 IC50 21.0 nM
O=C(O)CCCCCCCc1cccc2cncn12 CHEMBL49633 IC50 21.0 nM
CCOC(=O)CCCCO/N=C(\c1cccnc1)c1cccc(NC(=O)C2CSC(c3cccnc3)N2)c1 CHEMBL420137 IC50 21.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(NC(=O)C2CSC(c3cccnc3)N2)cc1)c1cccnc1 CHEMBL116673 IC50 21.0 nM
O=C(O)CCn1cc(Cn2ccnc2)c2cc(Cl)ccc21 CHEMBL331822 IC50 21.0 nM
Cc1[nH]c2ccc(CCC(=O)O)cc2c1Cc1ccncc1 CHEMBL103580 IC50 22.0 nM
O=C(O)c1ccc2sc(Cn3ccnc3)c(Cl)c2c1 CHEMBL296006 IC50 22.0 nM
CN(C)S(=O)(=O)NCCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1 CHEMBL115636 IC50 22.0 nM
O=C(O)CCc1cc(CCNC(=O)c2ccccc2)cc(Cc2cccnc2)c1 CHEMBL119670 IC50 22.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)N2CCCC2)cc(Cc2cccnc2)c1 CHEMBL326356 IC50 22.0 nM
O=C(O)CC/C=C\CC[C@@H]1[C@@H](c2cccnc2)OC[C@H]1OCc1ccc(-c2ccccc2)cc1 CHEMBL302457 IC50 22.0 nM
CC(C)(Oc1ccc(Br)cc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159859 IC50 22.0 nM
CSc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c([N+](=O)[O-])c1 CHEMBL159778 IC50 22.0 nM
CC(C)(C)/N=C(/S)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL281338 IC50 22.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc(-c2nc(C(=O)NCCCCC3CCCCC3)co2)c1 CHEMBL57359 IC50 23.0 nM
O=C(O)CCCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL127017 IC50 24.0 nM
O=C(O)CCC/C=C(\CCCNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 CHEMBL338546 IC50 24.0 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC2C)CCN(Cc1cccc(/C(=N\OCCCCC(=O)O)c2cccnc2)c1)C3 CHEMBL164665 IC50 24.0 nM
O=C(O)/C=C/c1ccc(Cn2ccnc2)cc1 CHEMBL11662 IC50 24.0 nM
N#Cc1ccc(C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)cc1 CHEMBL159699 IC50 24.0 nM
CC(C)/N=C(/NC#N)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL22721 IC50 24.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCc3ccccc3)co2)cc1)c1cccnc1 CHEMBL57576 IC50 24.7 nM
CC(C)N(CCc1ccc(/C(=C\CCCC(=O)O)c2cccnc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL419790 IC50 25.0 nM
Cc1c(Cn2ccnc2)ccc2c(C(=O)O)cccc12 CHEMBL44365 IC50 25.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCC3CC3)co2)cc1)c1cccnc1 CHEMBL60710 IC50 25.0 nM
C/C(=C\c1ccc(C(C)c2cccnc2)cc1)C(=O)O CHEMBL553319 IC50 25.0 nM
CC(C)(Oc1ccc(Cn2ccnc2)cc1)C(=O)O CHEMBL555076 IC50 25.0 nM
Cc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c(C#N)c1 CHEMBL445644 IC50 25.0 nM
O=C(O)C(Cl)CCCCCCn1ccnc1 CHEMBL545601 IC50 25.0 nM
CC(C)C/N=C(/NC#N)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL21513 IC50 25.0 nM
CC(C)(C)/N=C(\Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1)NS(C)(=O)=O CHEMBL277620 IC50 25.0 nM
c1ccc2c(Cn3ccnc3)c[nH]c2c1 CHEMBL116794 IC50 25.0 nM
CC(C)(Oc1cccc(F)c1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL435049 IC50 26.0 nM
CN(C)/C(=N/c1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1)NC#N CHEMBL280380 IC50 26.0 nM
O=C(O)CCc1ccc(CCCNS(=O)(=O)c2ccc(Cl)cc2)cc1CCc1cccnc1 CHEMBL287956 IC50 26.0 nM
O=C(O)c1ccc(OCCCn2ccnc2)cc1 CHEMBL33731 IC50 27.0 nM
O=C(O)c1ccc2sc(Cn3ccnc3)c(Br)c2c1 CHEMBL47189 IC50 27.0 nM
O=C(O)c1ccc(/C=C(\c2ccc(CCNS(=O)(=O)c3ccc(Cl)cc3)cc2)c2cccnc2)cc1 CHEMBL126333 IC50 27.0 nM
O=C(O)CCc1cc(CCCS(=O)(=O)c2ccccc2)cc(Cc2cccnc2)c1 CHEMBL114063 IC50 27.0 nM
Cc1c(Cn2ccnc2)c2ccccc2n1CCC(=O)O CHEMBL283656 IC50 28.0 nM
C#CCC(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL101841 IC50 28.0 nM
C=C(C)C(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL98952 IC50 28.0 nM
O=C(O)/C=C/C=C/c1cccc2cncn12 CHEMBL48093 IC50 28.0 nM
COC1CCC(CCCNC(=O)c2coc(-c3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)n2)CC1 CHEMBL357723 IC50 28.7 nM
Cc1c(C(=O)O)sc2ccc(Cn3ccnc3)cc12 CHEMBL42424 IC50 29.0 nM
CCN(CC)S(=O)(=O)NCCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1 CHEMBL115806 IC50 29.0 nM
CCCS(=O)(=O)NCCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1 CHEMBL113753 IC50 29.0 nM
Cc1ccsc1/C(=C/CCCCC(=O)O)c1cccnc1 CHEMBL430495 IC50 29.0 nM
O=C(O)CCCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL319769 IC50 29.0 nM
CC(C)(Oc1ccccc1Br)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL161911 IC50 29.0 nM
O=C(O)CC/C=C\C[C@@H]1C2CCC(C2)[C@@H]1c1cccnc1 CHEMBL50916 IC50 29.0 nM
Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL808 IC50 29.0 nM
CC(C)(CCCCOc1ccc(/C(=C\CCCCC(=O)O)c2cccnc2)cc1)[C@H]1OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c2ccccc2O)O1 CHEMBL263516 IC50 30.0 nM
O=C(O)c1ccc2oc(Cn3ccnc3)c(Br)c2c1 CHEMBL43218 IC50 30.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2cccc(OCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)c2)O[C@@H]1c1ccccc1O CHEMBL290281 IC50 30.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccccc2OCCOc2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL44422 IC50 30.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](CCOc2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL41945 IC50 30.0 nM
CC(C)(c1ccc(/C(=C\CCCCC(=O)O)c2cccnc2)cc1)[C@H]1OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c2ccccc2O)O1 CHEMBL290882 IC50 30.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccccc2OCCOc2cc(C(=O)O)ccc2OCCn2ccnc2)O[C@@H]1c1ccccc1O CHEMBL290483 IC50 30.0 nM
O=C(O)CCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL101542 IC50 30.0 nM
CC(C)(CCC/C=C(/c1ccccc1)c1cccnc1)C(=O)O CHEMBL98840 IC50 30.0 nM
CSC(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL98443 IC50 30.0 nM
Cc1ccc(SC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c([N+](=O)[O-])c1 CHEMBL159528 IC50 30.0 nM
CC(CCCCCCn1ccnc1)C(=O)O CHEMBL555077 IC50 30.0 nM
O=C(O)CCCCC#CCn1ccnc1 CHEMBL541024 IC50 30.0 nM
CC(C)(CCCCCCn1ccnc1)C(=O)O CHEMBL545367 IC50 30.0 nM
O=C(O)Cn1cc(Cn2ccnc2)c2ccccc21 CHEMBL117851 IC50 30.0 nM
O=C(O)CCCCCC(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL339335 IC50 31.0 nM
O=C(O)c1ccc2oc(Cn3ccnc3)c(Cl)c2c1 CHEMBL557333 IC50 31.0 nM
O=C(O)COc1ccc(Cn2ccnc2)cc1 CHEMBL42341 IC50 31.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1ccsc1 CHEMBL98439 IC50 31.0 nM
CCCCCNC(=O)c1coc(-c2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)n1 CHEMBL291539 IC50 31.2 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(I)cc2)c1 CHEMBL348790 Log IC50 31.62 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(F)cc2)c1 CHEMBL351657 Log IC50 31.62 nM
CC(C)(CNS(=O)(=O)c1ccc(I)cc1)c1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL162641 Log IC50 31.62 nM
Cc1c(Cn2ccnc2)n(C)c2ccc(C(=O)O)cc12 CHEMBL46571 IC50 32.0 nM
O=C(O)Cc1ccc(OCCn2ccnc2)cc1 CHEMBL30766 IC50 32.0 nM
O=C(O)CC/C=C\CC[C@H]1[C@@H](OCc2ccc(-c3ccccc3)cc2)CO[C@H]1c1cccnc1 CHEMBL65622 IC50 32.0 nM
O=C(O)C(CCC/C=C(/c1cccnc1)c1cccs1)c1ccccc1 CHEMBL98444 IC50 32.0 nM
O=C(O)CCCCCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL101813 IC50 32.0 nM
O=C(O)CCCCCCCn1ccnc1 CHEMBL542051 IC50 32.0 nM
O=C(O)/C=C/c1cccc(Cn2ccnc2)c1 CHEMBL542053 IC50 32.0 nM
CC(C)(Oc1ccccc1O)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL348968 IC50 32.0 nM
COC(=O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL126337 IC50 33.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCOC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL150289 IC50 33.0 nM
O=C(O)c1cc2ccc(Cn3ccnc3)cc2[nH]1 CHEMBL42283 IC50 33.0 nM
O=C(O)C(CCC/C=C(\c1ccccc1)c1cccnc1)Sc1ccccc1 CHEMBL329064 IC50 33.0 nM
O=C(O)c1ccc2cc(Cn3ccnc3)ccc2c1 CHEMBL295673 IC50 34.0 nM
Cc1c(Cn2ccnc2)oc2ccc(C(=O)O)cc12 CHEMBL44149 IC50 34.0 nM
O=C(O)c1csc2c(Cn3ccnc3)cccc12 CHEMBL296945 IC50 34.0 nM
O=C(O)CCn1cc(Cn2ccnc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21 CHEMBL295512 IC50 34.0 nM
O=C(O)c1cc2cc(Cn3ccnc3)ccc2o1 CHEMBL288473 IC50 34.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc2ccccc12 CHEMBL320158 IC50 34.0 nM
CC(C)(Oc1ccc(S(C)(=O)=O)cc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159737 IC50 34.0 nM
C=C(NC(=O)c1ccc(/C(=C\CCCCC(=O)O)c2cccnc2)cc1)C(=O)NCCCCC1CCCCC1 CHEMBL147444 IC50 35.7 nM
CSc1ccccc1OC(C)(C)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL352196 IC50 36.0 nM
COc1ccc(COC[C@H](Cn2ccnc2)OCCCCC(C)(C)C(=O)O)cc1 CHEMBL51802 IC50 36.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCOCC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL346644 IC50 36.7 nM
Cc1c(Cn2ccnc2)[nH]c2ccc(C(=O)O)cc12 CHEMBL289812 IC50 37.0 nM
Cc1ccc(S(=O)(=O)NCCc2cc(CCC(=O)O)cc(Cc3cccnc3)c2)cc1 CHEMBL116704 IC50 37.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Oc2cccnc2)c1 CHEMBL117538 IC50 37.0 nM
CC(C)(CCC/C=C(\c1cccnc1)c1cccs1)C(=O)O CHEMBL330592 IC50 37.0 nM
COc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c([N+](=O)[O-])c1 CHEMBL423248 IC50 37.0 nM
CC(C)(Cc1ccccc1C#N)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159268 IC50 37.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cn2ccnc2)c1 CHEMBL418852 IC50 38.0 nM
CC(c1cccnc1)c1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(CCC(=O)O)c1 CHEMBL114456 IC50 38.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccccc2)cc(Oc2cccnc2)c1 CHEMBL118084 IC50 38.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)Nc2ccc(Cl)cc2)cc(Cc2cccnc2)c1 CHEMBL117373 IC50 38.0 nM
CC(C)(CCCC/C=C(/c1ccccc1)c1cccnc1)C(=O)O CHEMBL328646 IC50 38.0 nM
O=C(O)C(CCCCCCn1ccnc1)c1ccccc1 CHEMBL545599 IC50 38.0 nM
CC(Oc1ccc(Cn2ccnc2)cc1)C(=O)O CHEMBL534331 IC50 38.0 nM
O=C(O)CCCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCCC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL61306 IC50 38.0 nM
Cc1c(Cn2ccnc2)c2cc(CCC(=O)O)ccc2n1CCNS(=O)(=O)c1ccc(F)cc1 CHEMBL432958 IC50 39.0 nM
Cc1c(Cn2ccnc2)n(CCCCNS(=O)(=O)c2ccc(F)cc2)c2ccc(C(=O)O)cc12 CHEMBL321549 IC50 39.0 nM
O=C(O)CCCCO/N=C(/c1cncnc1)c1cccc(C(F)(F)F)c1 CHEMBL129843 IC50 39.0 nM
NC(=O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL127212 IC50 39.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cc2cccnc2)c1 CHEMBL63090 IC50 39.0 nM
CC(C)(C)CS(=O)(=O)NCCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1 CHEMBL324059 IC50 39.0 nM
O=C(O)CCCCCCn1ccnc1 CHEMBL557994 IC50 39.0 nM
O=C(O)CC/C=C\CC1COC(c2ccc([N+](=O)[O-])cc2)OC1c1cccnc1 CHEMBL159571 IC50 39.0 nM
CSc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)cc1 CHEMBL161304 IC50 39.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc([N+](=O)[O-])cc2)c1 CHEMBL162879 Log IC50 39.81 nM
O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCCC#Cc3cccnc3)c1)c1ccc(F)cc21 CHEMBL175801 IC50 40.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccc(Cl)c(Cl)c1)c1cccnc1 CHEMBL556044 IC50 40.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](CCCCCCCCCCOc2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL44865 IC50 40.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2cccc(OCCOc3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)c2)O[C@@H]1c1ccccc1O CHEMBL41904 IC50 40.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(OCCCCCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL288194 IC50 40.0 nM
O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCn1ccnc1 CHEMBL136918 IC50 40.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](C(CCC/C=C(/c2ccccc2)c2cccnc2)C(=O)O)O[C@@H]1c1ccccc1O CHEMBL417163 IC50 40.0 nM
O=C(O)c1ccc2c(Cl)c(Cn3ccnc3)sc2c1 CHEMBL47165 IC50 40.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(/C(=C\CCCCC(=O)O)c3cccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL42738 IC50 40.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2cccc(COc3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)c2)O[C@@H]1c1ccccc1O CHEMBL43468 IC50 40.0 nM
O=C(O)/C=C/C=C/CCCn1ccnc1 CHEMBL541522 IC50 40.0 nM
COc1ccc(SC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c([N+](=O)[O-])c1 CHEMBL159559 IC50 40.0 nM
CC(C)(Sc1ccccc1C#N)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159420 IC50 40.0 nM
CC(C)(C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1)S(=O)(=O)c1ccccc1 CHEMBL159356 IC50 40.0 nM
O=C(O)COc1ccc(Cn2ccnc2)cc1 CHEMBL544900 IC50 40.0 nM
O=C(O)CC/C=C\CC1COC(c2cccc3ccccc23)OC1c1cccnc1 CHEMBL160657 IC50 40.0 nM
CC(C)(Sc1ccccc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL350225 IC50 40.0 nM
O=C(O)/C=C/CCCCCc1cccc2cncn12 CHEMBL295364 IC50 40.0 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CCCC(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL165359 IC50 41.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1ccc2c(c1)OCO2 CHEMBL430678 IC50 41.0 nM
COCC(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL329965 IC50 41.0 nM
O=C(O)CCCCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL97978 IC50 41.0 nM
COc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)cc1 CHEMBL352075 IC50 41.0 nM
O=C(O)CCCCc1cccc2cncn12 CHEMBL443001 IC50 41.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCOC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL347343 IC50 42.0 nM
O=C(O)CCCCCCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL98601 IC50 42.0 nM
CC(C)(O)C(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL98901 IC50 42.0 nM
O=C(O)CCCCC=C=Cn1ccnc1 CHEMBL542547 IC50 42.0 nM
O=C(O)CC/C=C\CC1COC(c2ccc(Cl)c(Cl)c2)OC1c1cccnc1 CHEMBL422719 IC50 42.0 nM
O=C(O)C#CCCCCCn1ccnc1 CHEMBL542545 IC50 42.0 nM
O=C(O)CC/C=C\CC1COC(c2ccc(Cl)cc2Cl)OC1c1cccnc1 CHEMBL355596 IC50 42.0 nM
CCn1c(/C=C(/C)C(=O)O)ccc1Cc1cccnc1 CHEMBL353950 IC50 42.0 nM
Cc1ccc2c(c1)c(Cn1ccnc1)cn2CCC(=O)O CHEMBL326710 IC50 42.0 nM
O=C(O)CCCCCc1cnccc1CCNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL298009 IC50 43.0 nM
O=C(O)CCC/C=C\C[C@@H]1[C@@H](c2cccnc2)SC[C@H]1OCc1ccc(-c2ccccc2)cc1 CHEMBL65161 IC50 43.0 nM
O=C(O)CCC/C=C(\c1ccc(CCN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL129000 IC50 43.0 nM
O=C(O)CCC/C=C(\c1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL128104 IC50 43.0 nM
CSc1c(Cn2ccnc2)sc2ccc(C(=O)O)cc12 CHEMBL46561 IC50 43.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)N2CCCCC2)cc(Cc2cccnc2)c1 CHEMBL119035 IC50 43.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)C2CCCCC2)cc(Cc2cccnc2)c1 CHEMBL117224 IC50 43.0 nM
CC(C)(CCCC/C=C(\c1cccnc1)c1cccs1)C(=O)O CHEMBL419900 IC50 43.0 nM
O=C(O)CCc1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)c(CCc2cccnc2)c1 CHEMBL43384 IC50 43.0 nM
COc1ccc2c(c1)c(Cn1ccnc1)cn2CCC(=O)O CHEMBL419943 IC50 43.0 nM
CC1=C(C)C(=O)C(C(CCCCCCC(=O)O)c2cccnc2)=C(C)C1=O CHEMBL92414 IC50 44.0 nM
CN(C)C(=O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL127681 IC50 44.0 nM
O=C(O)c1ccc(/C=C/Cn2ccnc2)cc1 CHEMBL542303 IC50 44.0 nM
O=C(O)CC/C=C\CC1COC(c2ccc(C(F)(F)F)cc2)OC1c1cccnc1 CHEMBL161435 IC50 44.0 nM
C/C(=C/c1cc(Cc2cccnc2)n(C(C)(C)C)c1)C(=O)O CHEMBL170754 IC50 44.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(C(=O)N2CCN(C(=O)C3CSC(c4cccnc4)N3)CC2)cc1)c1cccnc1 CHEMBL539177 IC50 44.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccccc2)cc(Cc2cccnc2)c1 CHEMBL116196 IC50 45.0 nM
CC(C)(CCCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL95554 IC50 45.0 nM
CC(C)(Oc1ccccc1C#N)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL161608 IC50 45.0 nM
CC(C)(Oc1ccccc1F)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL353356 IC50 45.0 nM
CC(C)(Cc1ccc(F)cc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159876 IC50 45.0 nM
CC(C)(Oc1ccccc1S(C)(=O)=O)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL350510 IC50 45.0 nM
O=C(O)CCC/C=C(\c1ccc(CCN(Cc2ccc(C(=O)O)cc2)S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL127008 IC50 46.0 nM
CC(C)(Oc1ccc(C#N)cc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL161357 IC50 46.0 nM
O=C(O)C1(CCCCCCn2ccnc2)CCCCC1 CHEMBL555626 IC50 46.0 nM
O=C(O)/C=C/c1ccc(Cc2cccnc2)s1 CHEMBL557591 IC50 47.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cc2ccncc2)c1 CHEMBL65378 IC50 47.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCOCc3ccccc3)co2)cc1)c1cccnc1 CHEMBL151860 IC50 47.5 nM
O=C(O)CCn1cc(Cc2cccnc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21 CHEMBL47612 IC50 48.0 nM
O=C(O)CCc1cc(CCS(=O)(=O)c2ccccc2)cc(Cc2cccnc2)c1 CHEMBL115805 IC50 48.0 nM
CC(C)(CCCC/C=C(/c1cccnc1)c1cccs1)C(=O)O CHEMBL97891 IC50 48.0 nM
O=C(O)CC/C=C\CC1COC(c2ccccc2Cl)OC1c1cccnc1 CHEMBL161105 IC50 48.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCCOc3ccccc3)co2)cc1)c1cccnc1 CHEMBL150252 IC50 48.9 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCCOC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL150660 IC50 49.0 nM
O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Br)cc2)cc(Cc2cccnc2)c1 CHEMBL118008 IC50 49.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCCCOc3ccccc3)co2)cc1)c1cccnc1 CHEMBL150436 IC50 49.2 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCOc4cccnc4)cn3c(=O)c2c1 CHEMBL1202758 IC50 50.0 nM
O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCC#Cc3cccnc3)c1)c1ccc(F)cc21 CHEMBL175538 IC50 50.0 nM
Cc1ccc(S(=O)(=O)NCC(CCCCCC(=O)O)c2cccnc2)cc1 CHEMBL553822 IC50 50.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc3cc(/C(=C\CCCCC(=O)O)c4cccnc4)ccc3c2)O[C@@H]1c1ccccc1O CHEMBL287720 IC50 50.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(CCOc3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)cc2)O[C@@H]1c1ccccc1O CHEMBL43488 IC50 50.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(OCCOc3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)cc2)O[C@@H]1c1ccccc1O CHEMBL290205 IC50 50.0 nM
Cc1ccc(OC(C)(C)[C@H]2OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c3cncn3C)O2)c([N+](=O)[O-])c1 CHEMBL278714 IC50 50.0 nM
O=C(O)C(CCC/C=C(\c1cccnc1)c1cccs1)c1ccccc1 CHEMBL263019 IC50 50.0 nM
C=CCC(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL330442 IC50 50.0 nM
Cc1ccc(C#N)c(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)c1 CHEMBL350816 IC50 50.0 nM
O=C(O)CC/C=C\CC1COC(c2ccc3ccccc3c2)OC1c1cccnc1 CHEMBL345572 IC50 50.0 nM
C/C(=C/c1ccc(Cc2cccnc2)n1C)C(=O)O CHEMBL352763 IC50 50.0 nM
O=C(O)CCC/C=C\C[C@@H]1C2CCC(C2)[C@@H]1c1cccnc1 CHEMBL430965 IC50 50.0 nM
CC(C)(C)NC(Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1)=C(C#N)C#N CHEMBL21570 IC50 50.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccccc2)c1 CHEMBL159447 Log IC50 50.12 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccccc2[N+](=O)[O-])c1 CHEMBL164109 Log IC50 50.12 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCCNS(=O)(=O)c2ccccc2)c1 CHEMBL422017 Log IC50 50.12 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCN3CCOCC3)co2)cc1)c1cccnc1 CHEMBL424139 IC50 50.8 nM
CC(C)(Oc1ccc(F)cc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL163278 IC50 51.0 nM
O=C(O)c1cc2c(O)cc(Cn3ccnc3)cc2s1 CHEMBL290733 IC50 52.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc(C(F)(F)F)c1 CHEMBL99223 IC50 52.0 nM
CC(C)(Oc1ccccc1)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159196 IC50 52.0 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(C(=O)N2CCN(C(=O)C3CSC(c4cccnc4)N3)CC2)c1 CHEMBL117889 IC50 52.0 nM
C=C(c1cccnc1)c1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(CCC(=O)O)c1 CHEMBL117561 IC50 53.0 nM
CC(C)(/C=C/C(=O)O)CCCCn1ccnc1 CHEMBL537920 IC50 53.0 nM
O=C(O)c1ccc2c(c1)C(NCc1cccnc1)c1ccccc1CO2 CHEMBL296746 IC50 54.0 nM
CN(CCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1)S(=O)(=O)c1ccc(Cl)cc1 CHEMBL117294 IC50 54.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1cccs1 CHEMBL98282 IC50 54.0 nM
N#Cc1ccccc1C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL161104 IC50 54.0 nM
O=C(O)CCc1ccc(Cn2ccnc2)cc1 CHEMBL542546 IC50 54.0 nM
O=C(O)CCCCCC[C@@H]1C2CCC(C2)[C@@H]1c1cccnc1 CHEMBL51526 IC50 54.0 nM
O=C(O)CCC/C=C\C[C@@H]1C2CCC(C2)C1c1cccnc1 CHEMBL51158 IC50 54.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCCCC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL299467 IC50 55.0 nM
O=C(O)CCCCCCCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL101812 IC50 55.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc(F)c1 CHEMBL330187 IC50 55.0 nM
NC(=O)c1ccc(OCCn2ccnc2)cc1 CHEMBL30395 IC50 56.0 nM
C/C(=C\C(=O)O)c1ccc(Cc2cccnc2)cc1 CHEMBL536794 IC50 56.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1ccc2c(c1)OCO2 CHEMBL98690 IC50 56.0 nM
O=C(O)CCCC/C=C\Cn1ccnc1 CHEMBL542301 IC50 56.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(COCC(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)cc1)c1cccnc1 CHEMBL349982 IC50 58.0 nM
O=C(O)C(CCC/C=C(\c1ccccc1)c1cccnc1)Cc1ccccc1 CHEMBL420086 IC50 58.0 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL350961 IC50 59.0 nM
CC(C)Oc1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL57716 IC50 60.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3ccc(O)cc3c(=O)n2c1 CHEMBL57480 IC50 60.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2ccc(OCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)cc2)O[C@@H]1c1ccccc1O CHEMBL43756 IC50 60.0 nM
NC(=O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL136149 IC50 60.0 nM
O=C(O)CCO/N=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL126494 IC50 60.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](CCCCCOc2cc(C(=O)O)ccc2OCCn2ccnc2)O[C@@H]1c1ccccc1O CHEMBL44094 IC50 60.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1ccc2ccccc2c1 CHEMBL264871 IC50 60.0 nM
O=C(O)C(CCC/C=C(\c1ccccc1)c1cccnc1)C1=CCCC1 CHEMBL98845 IC50 60.0 nM
COc1ccccc1OC(C)(C)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL162032 IC50 60.0 nM
CCOC(=O)CCCC/[N+]([O-])=C(/c1cccnc1)c1cccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL29639 IC50 60.0 nM
Cc1c(Cc2cccnc2)c2cc(CCC(=O)O)ccc2n1CCNS(=O)(=O)c1ccc(F)cc1 CHEMBL320235 IC50 61.0 nM
CC(O)(c1cccnc1)c1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(CCC(=O)O)c1 CHEMBL116970 IC50 61.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1ccsc1 CHEMBL328191 IC50 62.0 nM
CCOC(=O)CCCC/[N+]([O-])=C(/c1cccnc1)c1cccc(COC(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NCc3nnc(C)n3-4)C2)c1 CHEMBL28642 IC50 62.0 nM
CC1=C(C)C(=O)C(C(CCCCCC(=O)O)c2cccnc2)=C(C)C1=O CHEMBL420251 IC50 63.0 nM
O=C(O)CCCC/C=C(\c1ccc(-c2nc(C(=O)NCCOCC3CCCCO3)co2)cc1)c1cccnc1 CHEMBL147308 IC50 63.0 nM
CC(C)c1ccc(/C(=C/CCCCC(=O)O)c2cccnc2)cc1 CHEMBL99319 IC50 63.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1 CHEMBL159936 Log IC50 63.1 nM
Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O CHEMBL12131 IC50 64.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccc(-c2ccc3ccccc3c2)cc1)c1cccnc1 CHEMBL541097 IC50 65.0 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(C(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL323798 IC50 65.0 nM
O=C(O)CC/C=C\CC[C@H]1[C@H](OCc2ccc(-c3ccccc3)cc2)CO[C@H]1c1cccnc1 CHEMBL294353 IC50 65.0 nM
CCOC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NCc3nnc(C)n3-4)C2)c1 CHEMBL423993 IC50 65.0 nM
O=C(O)CCCC/C=C(/CCCc1ccccc1)c1cccnc1 CHEMBL102200 IC50 65.0 nM
O=C(O)CCCCC/C=C(/c1ccccc1)c1cccnc1 CHEMBL101098 IC50 65.0 nM
O=C(O)C(CCC/C=C(\c1ccccc1)c1cccnc1)C1(O)CCCC1 CHEMBL318048 IC50 65.0 nM
O=C(O)CCCCCc1cnccc1CNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL295049 IC50 66.0 nM
COC(=O)c1ccccc1OC(C)(C)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL159344 IC50 66.0 nM
CCOC(=O)CCCC/[N+]([O-])=C(/c1cccnc1)c1cccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NCc3nnc(C)n3-4)C2)c1 CHEMBL283814 IC50 67.0 nM
CCOC(=O)CCCC/C=C(/c1cccnc1)c1cccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL354662 IC50 68.0 nM
O=C(O)CCCCCCc1cccnc1 CHEMBL542052 IC50 68.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(CC(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)cc1)c1cccnc1 CHEMBL166193 IC50 69.0 nM
CCOC(=O)CCCC/[N+]([O-])=C(/c1cccnc1)c1cccc(COC(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL283815 IC50 69.0 nM
O=S(=O)(NCCCCC(CCCO)CCCc1cccnc1)c1ccc(Cl)cc1 CHEMBL136130 IC50 70.0 nM
O=C(O)CC/C=C\C[C@@H]1CO[C@H](c2cccc(OCCCCCCOc3ccc(/C(=C\CCCCC(=O)O)c4cccnc4)cc3)c2)O[C@@H]1c1ccccc1O CHEMBL41989 IC50 70.0 nM
Cn1cncc1[C@H]1OC(C)(C)OC[C@H]1C/C=C\CCC(=O)O CHEMBL18422 IC50 70.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1ccccc1F CHEMBL316848 IC50 70.0 nM
O=C(O)C(CCCCc1cccc2cncn12)CCC(=O)N1c2ccccc2C[C@H]1C(=O)O CHEMBL53754 IC50 70.0 nM
O=C(O)/C=C/CCCCCn1ccnc1 CHEMBL545366 IC50 70.0 nM
Cc1c(Cn2ccnc2)c2ccccc2n1/C=C/C(=O)O CHEMBL115844 IC50 70.0 nM
O=C(O)c1cccc2cc(Cn3ccnc3)ccc12 CHEMBL42217 IC50 71.0 nM
C/C(=C/CCCCC(=O)O)c1cccnc1 CHEMBL98941 IC50 71.0 nM
O=C(O)CC/C=C\CC1COC(c2cccs2)OC1c1cccnc1 CHEMBL349160 IC50 71.0 nM
CC(C)(CCCCn1ccnc1)CCC(=O)O CHEMBL545600 IC50 71.0 nM
CCOC(=O)CCCC/C=C(\c1ccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)cc1)c1cccnc1 CHEMBL349150 IC50 72.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(C(=O)N2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)cc1)c1cccnc1 CHEMBL408135 IC50 72.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(CN2CCN(C(=O)C3CSC(c4cccnc4)N3)CC2)cc1)c1cccnc1 CHEMBL324118 IC50 72.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc([N+](=O)[O-])c1 CHEMBL330440 IC50 73.0 nM
O=C(O)CCCCO/N=C(\c1ccccc1)c1cncnc1 CHEMBL131949 IC50 75.0 nM
CCCCCC/C(=C/CCCCC(=O)O)c1cccnc1 CHEMBL99551 IC50 75.0 nM
O=C(O)CCCCCCCc1cccnc1 CHEMBL543725 IC50 76.0 nM
CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1 CHEMBL163 IC50 76.0 nM
O=C(O)CCCCC(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 CHEMBL542490 IC50 77.0 nM
NC(=O)CCCCCc1cccc2cncn12 CHEMBL417716 IC50 77.0 nM
Cc1c(Cc2ccncc2)c2cc(CCC(=O)O)ccc2n1CCNS(=O)(=O)c1ccc(F)cc1 CHEMBL102533 IC50 78.0 nM
O=C(O)CC/C=C\C[C@@H]1C2CCC(C2)[C@H]1c1cccnc1 CHEMBL298130 IC50 78.0 nM
Cc1c(Cc2ccncc2)n(CCNS(=O)(=O)c2ccc(F)cc2)c2ccc(CCC(=O)O)cc12 CHEMBL198965 IC50 78.0 nM
O=C(O)CCCCO/N=C(\c1ccccc1)c1cnccn1 CHEMBL130564 IC50 79.0 nM
O=C(O)CC/C=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccccc2)c1 CHEMBL347812 Log IC50 79.43 nM
O=C(O)CCCCCCc1cnccc1CCNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL42480 IC50 80.0 nM
CC1(C)OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c2cncs2)O1 CHEMBL17797 IC50 80.0 nM
CCOC(=O)CCCCO/N=C(\c1ccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)cc1)c1cccnc1 CHEMBL164123 IC50 80.0 nM
COc1ccc(/C(=C/CCCCC(=O)O)c2cccnc2)cc1 CHEMBL101785 IC50 80.0 nM
O=C(O)CCCC/C=C(/c1ccc(Br)cc1)c1cccnc1 CHEMBL100755 IC50 82.0 nM
CN(C)c1ccc2c(c1)c(Cn1ccnc1)cn2CCC(=O)O CHEMBL117652 IC50 82.0 nM
O=C(O)CCCC/C=C(\c1ccc(C2=N[C@@H](C(=O)NCCCCC3CCCCC3)CO2)cc1)c1cccnc1 CHEMBL56778 IC50 82.1 nM
O=C(O)CCCC/C=C(\c1ccc(C2=N[C@H](C(=O)NCCCCC3CCCCC3)CO2)cc1)c1cccnc1 CHEMBL58332 IC50 82.1 nM
O=C(O)CCCC/C=C(/c1ccc(F)cc1)c1cccnc1 CHEMBL98694 IC50 83.0 nM
Cc1ccc(/C(=C/CCCCC(=O)O)c2cccnc2)cc1 CHEMBL98251 IC50 85.0 nM
O=C(O)C1CCc2sc(Cn3ccnc3)cc2C1 CHEMBL281646 IC50 86.0 nM
O=C(O)CCCCCc1cccnc1 CHEMBL557796 IC50 86.0 nM
CCOC(=O)CCCCO/N=C(\c1cccnc1)c1cccc(CN2CCN(C(=O)C3CSC(c4cccnc4)N3)CC2)c1 CHEMBL114843 IC50 88.0 nM
CC1=C(C)C(=O)C(C(CCCCC(=O)O)c2cccnc2)=C(C)C1=O CHEMBL91799 IC50 89.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccc(-c2cccc3ccccc23)cc1)c1cccnc1 CHEMBL555812 IC50 90.0 nM
O=C(O)C(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL136997 IC50 90.0 nM
Cc1cccc(C#N)c1OC(C)(C)C1OCC(C/C=C\CCC(=O)O)C(c2cccnc2)O1 CHEMBL158687 IC50 90.0 nM
CC(C)(CCCCCCC(=O)O)n1ccnc1 CHEMBL552591 IC50 90.0 nM
O=C(O)C1=Cc2cc(Cn3ccnc3)sc2CC1 CHEMBL22484 IC50 93.0 nM
O=C(O)COc1ccc(OCCn2ccnc2)cc1 CHEMBL34041 IC50 95.0 nM
CC(C)(Sc1ccc(Cn2ccnc2)cc1)C(=O)O CHEMBL537923 IC50 95.0 nM
O=C(O)CCCC(c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL126373 IC50 98.0 nM
Cc1cc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2cc1C CHEMBL1204215 IC50 100.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4ccncc4)cn3c(=O)c2c1 CHEMBL1204224 IC50 100.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL1204213 IC50 100.0 nM
Cc1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL300338 IC50 100.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3ccc(Br)cc3c(=O)n2c1 CHEMBL58518 IC50 100.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL1204214 IC50 100.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL1204216 IC50 100.0 nM
O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCCc3cccnc3)c1)c1ccc(F)cc21 CHEMBL425325 IC50 100.0 nM
CCCc1ccncc1-c1ccc(CO[C@@H]2CC[C@H](N3CCCCCC3)[C@H]2OC/C=C\CCC(=O)O)cc1 CHEMBL159517 Log IC50 100.0 nM
CCCCc1ccncc1-c1ccc(CO[C@@H]2CC[C@H](N3CCCCCC3)[C@H]2OC/C=C\CCC(=O)O)cc1 CHEMBL158576 Log IC50 100.0 nM
Cc1ccncc1-c1ccc(CO[C@@H]2CC[C@H](N3CCCCCC3)[C@H]2OC/C=C\CCC(=O)O)cc1 CHEMBL349625 Log IC50 100.0 nM
O=C(O)CCCCCc1cnccc1CCCNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL42170 IC50 100.0 nM
O=C(O)CCC/C=C(\c1ccc(CCN(CCC(=O)O)S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL129365 IC50 100.0 nM
O=C(O)C1=Cc2cc(CCn3ccnc3)sc2CC1 CHEMBL23202 IC50 100.0 nM
O=C(O)CCCCC=C(c1cccnc1)c1cccnc1 CHEMBL98141 IC50 100.0 nM
COC(=O)CCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL330614 IC50 100.0 nM
Cc1c(-c2cccnc2)n(CCCCP(=O)(O)O)c2ccccc12 CHEMBL52471 IC50 100.0 nM
O=C(O)CC(CCCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCCc1cccnc1 CHEMBL136905 IC50 100.0 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL6 IC50 100.0 nM
O=C(O)CC/C=C(\c1ccccc1)c1cccnc1 CHEMBL317733 IC50 110.0 nM
CC(C)CSC(CCC/C=C(\c1ccccc1)c1cccnc1)C(=O)O CHEMBL98085 IC50 110.0 nM
O=C(O)c1cc2c(s1)CCC(Cn1ccnc1)C2 CHEMBL25711 IC50 114.0 nM
O=C(O)C1=Cc2cc(C(c3ccccc3)n3ccnc3)sc2CC1 CHEMBL23168 IC50 114.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 CHEMBL543915 IC50 120.0 nM
O=C(O)c1cc2cccc(Cn3ccnc3)c2s1 CHEMBL44446 IC50 120.0 nM
CC1(C)OC[C@@H](C/C=C\CCC(=O)O)[C@@H](c2cccnc2)O1 CHEMBL17912 IC50 120.0 nM
O=C(O)CCCc1ccc(-n2ccnc2)cc1 CHEMBL556173 IC50 120.0 nM
COc1ccc(COCC(Cn2ccnc2)OCCCCC(C)(C)C(=O)O)cc1 CHEMBL54268 IC50 120.0 nM
CCOC(=O)CCCCCOC(COCc1ccc(OC)cc1)Cn1ccnc1 CHEMBL301609 IC50 120.0 nM
O=C(O)CCC/C=C\C[C@@]1(c2cccnc2)C2CCC(C2)[C@H]1COc1ccc(-c2ccccc2)cc1 CHEMBL297712 IC50 120.0 nM
O=C(O)CCCCCC[C@@H]1C2CCC(C2)C1c1cccnc1 CHEMBL299878 IC50 125.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1ccccc1Br CHEMBL317387 IC50 130.0 nM
CCOCCn1cc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)cn2)ccc1=O CHEMBL4516982 IC50 132.0 nM
O=C(CCCCCCCn1ccnc1)c1ccccc1 CHEMBL15351 IC50 134.0 nM
Cc1c(Cn2ccnc2)n(CCNS(=O)(=O)c2ccc(F)cc2)c2ccc(CCC(=O)O)cc12 CHEMBL102692 IC50 135.0 nM
Cc1c(C(=O)O)sc2cc(OCCn3ccnc3)ccc12 CHEMBL44705 IC50 140.0 nM
O=C(O)C(O)CCCCCCn1ccnc1 CHEMBL544901 IC50 140.0 nM
Nc1ccc(C2(C3CCCCC3)CCC(=O)NC2=O)cc1 CHEMBL70901 IC50 150.0 nM
CC(C)(C)OC(=O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL127682 IC50 150.0 nM
O=C(O)C(=O)NC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 CHEMBL137187 IC50 150.0 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC2C)CCN(Cc1cccc(/C(=N\OCCCCC(=O)OCCN2CCOCC2)c2cccnc2)c1)C3 CHEMBL164758 IC50 151.0 nM
O=C(O)CC/C=C\CC1COC(c2ccco2)OC1c1cccnc1 CHEMBL160467 IC50 164.0 nM
O=C(O)CCCC/C=C\C[C@@H]1C2CCC(C2)C1c1cccnc1 CHEMBL51949 IC50 165.0 nM
O=C(NC(=O)c1ccc(OCCn2ccnc2)cc1)c1ccccc1 CHEMBL33874 IC50 180.0 nM
CC1=C(C)C(=O)C(/C(=C/CCCCC(=O)O)c2cccnc2)=C(C)C1=O CHEMBL420994 IC50 180.0 nM
CCCOC(=O)c1ccc(COC(COCc2ccc(OC)cc2)Cn2ccnc2)cc1 CHEMBL288824 IC50 180.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc(Br)c1 CHEMBL275548 IC50 180.0 nM
O=C(O)/C=C/CC/C=C\Cn1ccnc1 CHEMBL542304 IC50 180.0 nM
N#CN/C(=N/C1CCCCC1)Nc1ccc(/C(=C\CCCC(=O)O)c2cccnc2)cc1 CHEMBL277619 IC50 180.0 nM
Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 CHEMBL1221 IC50 183.0 nM
Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1 CHEMBL941 IC50 198.0 nM
O=C(O)CCCCO/N=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(I)cc2)c1 CHEMBL159481 Log IC50 199.53 nM
CC(C)(CNS(=O)(=O)c1ccc(I)cc1)c1cccc(/C(=N\OCCC(=O)O)c2cccnc2)c1 CHEMBL159979 Log IC50 199.53 nM
O=C(O)CCCO/N=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(I)cc2)c1 CHEMBL163276 Log IC50 199.53 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCn4ccnc4)cn3c(=O)c2c1 CHEMBL1204223 IC50 200.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL57736 IC50 200.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL60930 IC50 200.0 nM
COc1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL293362 IC50 200.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4cncnc4)cn3c(=O)c2c1 CHEMBL294706 IC50 200.0 nM
O=C(O)CC1CCCc2c1n(Cc1cccc(OCCC/C=C\c3cccnc3)c1)c1ccc(F)cc21 CHEMBL362418 IC50 200.0 nM
Cc1ccccc1S(=O)(=O)NCC(CCCCCC(=O)O)c1cccnc1 CHEMBL553313 IC50 200.0 nM
CCCCOC(=O)c1ccc(COC(COCc2ccc(OC)cc2)Cn2ccnc2)cc1 CHEMBL39172 IC50 200.0 nM
CC(C)C/N=C(/NC(N)=O)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL22363 IC50 200.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccccc1)c1cccnc1 CHEMBL557427 IC50 210.0 nM
O=C(O)CCc1ccc(Cc2cccnc2)cc1 CHEMBL542302 IC50 210.0 nM
C/C(=C\CCCCC(=O)O)c1cccnc1 CHEMBL99439 IC50 210.0 nM
O=C(O)COc1ccccc1Cn1ccnc1 CHEMBL541519 IC50 210.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 CHEMBL544377 IC50 220.0 nM
c1ccc(CNc2nc(-n3ccnc3)nc3ccccc23)cc1 CHEMBL118944 IC50 220.0 nM
O=C(O)CC/C=C\CC1COC(c2cccnc2)OC1c1cccnc1 CHEMBL422541 IC50 220.0 nM
O=C(O)CCCCCC(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 CHEMBL138325 IC50 220.0 nM
O=C(O)CCCCCCC/C=C(/c1ccccc1)c1cccnc1 CHEMBL100349 IC50 230.0 nM
O=C(O)CCC/C=C(\c1ccc(-c2nc(C(=O)NCCCCC3CCCCC3)co2)cc1)c1cccnc1 CHEMBL56722 IC50 230.0 nM
CC(C)(C)/N=C(\NC#N)Nc1cccc(/C(=N/OCCCCC(=O)O)c2cccnc2)c1 CHEMBL2093006 IC50 230.0 nM
CC(C)(C)Nc1c(Nc2cccc(/C(=C\CCCC(=O)O)c3cccnc3)c2)c(=O)c1=O CHEMBL2112933 IC50 230.0 nM
O=C(O)CCCCCCC(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 CHEMBL544150 IC50 240.0 nM
CNC(=O)CCC/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL129030 IC50 250.0 nM
O=C(O)CCCC/C=C\c1cccnc1 CHEMBL318459 IC50 250.0 nM
O=C(O)/C=C/c1ccc(OCCn2ccnc2)cc1 CHEMBL545364 IC50 250.0 nM
O=C(O)C(CO)CCCCCCn1ccnc1 CHEMBL542787 IC50 250.0 nM
C/N=C(/NC#N)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL21960 IC50 250.0 nM
O=C(O)CCCCO/N=C(\c1ccccc1)c1ccnnc1 CHEMBL130755 IC50 260.0 nM
Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL91 IC50 263.0 nM
CNC(=O)CCCCCc1cccc2cncn12 CHEMBL43734 IC50 270.0 nM
O=C(O)CCC/C=C(/c1ccccc1)c1cccnc1 CHEMBL97892 IC50 280.0 nM
CC(C)(C)c1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)cc1 CHEMBL159510 IC50 280.0 nM
OCCCCCCc1cccc2cncn12 CHEMBL541546 IC50 280.0 nM
C1=C(CCn2ccnc2)c2cccnc2CC1 CHEMBL293122 IC50 290.0 nM
CC(CCc1cccnc1)NC(=O)c1ccc2nc3ccc(C(C)C)cc3c(=O)n2c1 CHEMBL418452 IC50 300.0 nM
O=C(NCCCCc1cccnc1)c1ccc2nc3cc4c(cc3c(=O)n2c1)CCCC4 CHEMBL60572 IC50 300.0 nM
O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCCCc3cccnc3)c1)c1ccc(F)cc21 CHEMBL174388 IC50 300.0 nM
O=C(O)CCC/C=C(\c1ccc(CCN(CC(=O)O)S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL127738 IC50 310.0 nM
O=C(O)CCCCCCCC/C=C(/c1ccccc1)c1cccnc1 CHEMBL98536 IC50 310.0 nM
O=C(O)CCC/C=C(/c1cccnc1)c1cccc(N/C(=C/[N+](=O)[O-])NC2CCCCC2)c1 CHEMBL21392 IC50 310.0 nM
N#CN/C(=N/Cc1cccnc1)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL418188 IC50 320.0 nM
O=C(OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H](OC(=O)c2cc(O)c(O)c(OC(=O)c3cc(O)c(O)c(O)c3)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1)c1cc(O)c(O)c(OC(=O)c2cc(O)c(O)c(O)c2)c1 CHEMBL506247 IC50 325.0 nM
CCOC(=O)CCCCCc1cccc2cncn12 CHEMBL45932 IC50 330.0 nM
O=C(O)CC/C=C\C[C@@]1(c2cccnc2)C2CCC(C2)[C@H]1CNS(=O)(=O)c1ccc(Cl)cc1 CHEMBL51875 IC50 340.0 nM
O=C(O)CCC/C=C\c1c(Cc2cccnc2)ccc2c1CCC(NS(=O)(=O)c1ccc(Cl)cc1)C2 CHEMBL31854 IC50 350.0 nM
O=C1CCc2cc(C(c3ccccc3)n3ccnc3)ccc2N1 CHEMBL158201 IC50 350.0 nM
Cc1ccc(OC(C)(C)C2OCC(C/C=C\CCC(=O)O)C(c3cccnc3)O2)cc1 CHEMBL350595 IC50 360.0 nM
O=C(O)c1ccc2c(c1)OCc1ccccc1C2SCCNS(=O)(=O)c1ccccc1 CHEMBL331356 IC50 370.0 nM
Oc1ccc2cc(/C=C/n3ccnc3)ccc2n1 CHEMBL347379 IC50 380.0 nM
N#CN/C(=N/C1CC1)Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL281621 IC50 380.0 nM
CCOC(=O)CCC/C=C/CC(COCc1ccc(OC)cc1)Cn1ccnc1 CHEMBL53703 IC50 390.0 nM
CCNc1nc2c(C)c(Cc3cccnc3)c(O)c(C)c2s1 CHEMBL105587 IC50 390.0 nM
O=C(O)CCCCc1cccn2cncc12 CHEMBL48142 IC50 390.0 nM
CCc1cnccc1-c1ccc(CO[C@@H]2CC[C@H](N3CCCCCC3)[C@H]2OC/C=C\CCC(=O)O)cc1 CHEMBL350292 Log IC50 398.11 nM
O=C(O)CC1CCCc2c1n(Cc1ccc(OCCCCC#Cc3cccnc3)cc1)c1ccc(F)cc21 CHEMBL172198 IC50 400.0 nM
CC1=C(C)C(=O)C(Cc2cccnc2)=C(C)C1=O CHEMBL82479 IC50 400.0 nM
NC(=O)CCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL318937 IC50 400.0 nM
CCCCCCCCCn1ccnc1 CHEMBL15181 IC50 400.0 nM
CC(C)(C)/N=C(\NC#N)Nc1cccc(/C(=C\CCC(=O)O)c2cccnc2)c1 CHEMBL21072 IC50 400.0 nM
O=C(O)c1cc2cc(OCCn3ccnc3)ccc2s1 CHEMBL42440 IC50 420.0 nM
COc1ccc(COC[C@@H](Cn2ccnc2)OCCCCC(C)(C)C(=O)O)cc1 CHEMBL51367 IC50 420.0 nM
N#CN/C(N)=N\c1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1 CHEMBL428709 IC50 430.0 nM
O=C(O)c1ccc2c(c1)/C(=C/Cn1ccnc1)c1ccccc1CO2 CHEMBL116869 IC50 450.0 nM
O=C(O)CC/C=C(/c1ccccc1)c1cccnc1 CHEMBL318899 IC50 450.0 nM
CC(C)(CC/C=C/C=C/C(=O)O)n1ccnc1 CHEMBL554418 IC50 450.0 nM
O=C(O)CCCC/C=C(\c1cccnc1)c1cccc(C2=N[C@@H](C(=O)NCCCCC3CCCCC3)CO2)c1 CHEMBL294850 Kd 452.0 nM
Cc1nnc2n1-c1sc3c(c1C(c1ccccc1Cl)=NC2C)CCN(Cc1cccc(/C(=N\OCCCCC(=O)OCc2ccccc2)c2cccnc2)c1)C3 CHEMBL351562 IC50 465.0 nM
CC1=C(Cc2cccnc2)C(=O)c2ccccc2C1=O CHEMBL92863 IC50 490.0 nM
O=C(O)CCC/C=C(/c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL125519 IC50 490.0 nM
CCCCCCn1cncc1[C@H]1O[C@@H](C(C)(C)Oc2ccc(C)cc2[N+](=O)[O-])OC[C@H]1C/C=C\CCC(=O)O CHEMBL278458 IC50 490.0 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL10 IC50 494.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NC(C)(C)CCCc4cccnc4)cn3c(=O)c2c1 CHEMBL301215 IC50 500.0 nM
O=C(O)CC1CCCc2c1n(Cc1cccc(CCCCCc3cccnc3)c1)c1ccc(F)cc21 CHEMBL177596 IC50 500.0 nM
Cn1nc(-c2cncs2)c2ccccc2c1=O CHEMBL130453 IC50 500.0 nM
CC1=C(/C=C/C(=O)O)C(=O)C(C)=C(Cc2cccnc2)C1=O CHEMBL92083 IC50 500.0 nM
O=C(O)CCCCc1cccnc1 CHEMBL544201 IC50 500.0 nM
O=C(O)CC/C=C\CC1COC(c2ccsc2)OC1c1cccnc1 CHEMBL159873 IC50 500.0 nM
CCO/C(O)=C1\C(Cn2ccnc2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl CHEMBL440006 IC50 500.0 nM
O=C(O)CCO/N=C(/c1cccnc1)c1cccc(CCNS(=O)(=O)c2ccc(I)cc2)c1 CHEMBL161253 Log IC50 501.19 nM
CC1=C(C)C(=O)C(C(c2cccnc2)c2cccc(/C=C(\C)C(=O)O)c2)=C(C)C1=O CHEMBL327696 IC50 520.0 nM
O=C(O)CCCCCCCCC/C=C(/c1ccccc1)c1cccnc1 CHEMBL317605 IC50 520.0 nM
O=C(O)c1cccc(OCCn2ccnc2)c1 CHEMBL33407 IC50 530.0 nM
CCOC(=O)c1ccc(COC(COCc2ccc(OC)cc2)Cn2ccnc2)cc1 CHEMBL41908 IC50 540.0 nM
CCCNC(=O)CCCCO/N=C(/c1cccnc1)c1cccc(CN2CCc3c(sc4c3C(c3ccccc3Cl)=NC(C)c3nnc(C)n3-4)C2)c1 CHEMBL351024 IC50 540.0 nM
O=C1CCc2cc(-c3cccnc3)ccc2N1 CHEMBL62811 IC50 540.0 nM
O=C(O)C(CCCCCCn1ccnc1)C(=O)O CHEMBL544902 IC50 550.0 nM
CN(C)C(=O)CCCCCc1cccc2cncn12 CHEMBL542364 IC50 550.0 nM
COc1ccc(COCC(Cn2ccnc2)OCc2ccc(C(=O)Oc3ccccc3)cc2)cc1 CHEMBL289931 IC50 560.0 nM
COc1ccc(COCC(Cn2ccnc2)OCCCCCC(=O)O)cc1 CHEMBL299321 IC50 560.0 nM
O=C(O)CCCCO/N=C(/c1ccccc1)c1cncnc1 CHEMBL337048 IC50 573.0 nM
CC(C)c1ccc2nc3ccc(C(=O)N(C)CCCCc4cccnc4)cn3c(=O)c2c1 CHEMBL1202763 IC50 600.0 nM
CC(C)c1ccc2nc3ccc(C(=O)NCCSCc4cccnc4)cn3c(=O)c2c1 CHEMBL1202757 IC50 600.0 nM
O=C(O)CC1CCCc2c1n(Cc1ccc(OCCCC#Cc3cccnc3)cc1)c1ccc(F)cc21 CHEMBL427300 IC50 600.0 nM
CCOC(=O)CCCC/C=C(\c1ccccc1)c1cccnc1 CHEMBL98372 IC50 600.0 nM
CCO/C(O)=C1\C(Cn2ccnc2)=NC(Cn2ccnc2)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 CHEMBL1203671 IC50 600.0 nM
c1ccc(Cn2ccnc2)cc1 CHEMBL14192 IC50 602.0 nM
CCOC(=O)COc1ccc(OCCn2ccnc2)cc1 CHEMBL30861 IC50 610.0 nM
Clc1ccc(CO/N=C(\Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 CHEMBL1262 IC50 617.4 nM
O=C(O)CCCCO/N=C(/c1ccccc1)c1cnccn1 CHEMBL130790 IC50 620.0 nM
CC(=O)NC(=O)c1ccc(OCCn2ccnc2)cc1 CHEMBL418043 IC50 630.0 nM
c1cnc2c(c1)C(CCn1ccnc1)CCC2 CHEMBL292899 IC50 630.0 nM
N#CCCCCCc1cccc2cncn12 CHEMBL553274 IC50 630.0 nM
O=C(O)CC/C=C\CO[C@H]1[C@H](OCc2ccc(-c3cccnc3)cc2)CC[C@@H]1N1CCCCCC1 CHEMBL433884 Log IC50 630.96 nM
O=C(O)CC/C=C\CO[C@H]1[C@H](OCc2ccc(-c3ccncc3)cc2)CC[C@@H]1N1CCCCCC1 CHEMBL162691 Log IC50 630.96 nM
CCCc1c(Cc2cccnc2)cc2c(c1CCC(=O)O)CCC(NS(=O)(=O)c1ccc(Cl)cc1)C2 CHEMBL286412 IC50 640.0 nM
c1ccc(OCCn2ccnc2)cc1 CHEMBL284827 IC50 660.0 nM
C1=C(CCCn2ccnc2)c2cccnc2CC1 CHEMBL53290 IC50 680.0 nM
O=C(O)CCCCCO/N=C(/c1ccnnc1)c1cccc(C(F)(F)F)c1 CHEMBL336548 IC50 693.0 nM
CCOC(=O)c1ccc(COCC(Cn2ccnc2)OCc2ccc(C(=O)OCC)cc2)cc1 CHEMBL41231 IC50 700.0 nM
CC1=C(C)C(=O)C(C(C)c2cccnc2)=C(C)C1=O CHEMBL89938 IC50 720.0 nM
COc1ccc(COCC(Cn2ccnc2)OCCCCC(=O)O)cc1 CHEMBL301189 IC50 730.0 nM
CCOC(=O)CCCCOC(COCc1ccc(OC)cc1)Cn1ccnc1 CHEMBL53487 IC50 750.0 nM
O=C(O)CCC/C=C\C[C@@H]1C2CCC(C2)[C@@]1(CCCCCc1ccccc1)c1cccnc1 CHEMBL301520 IC50 790.0 nM
CC(C)(O)C#Cc1ccc2c(c1)c1cc(Cl)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 CHEMBL483900 IC50 800.0 nM
CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1 CHEMBL105386 IC50 810.0 nM
CCC(C1=C(C)C(=O)C(C)=C(C)C1=O)c1cccnc1 CHEMBL90996 IC50 830.0 nM
c1ccc(CNc2nc(-c3ccncc3)nc3ccccc23)cc1 CHEMBL118462 IC50 830.0 nM
O=C(NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21)Nc1ccccc1 CHEMBL114751 IC50 830.0 nM
NC(=O)Nc1ccc(OCCn2ccnc2)cc1 CHEMBL33151 IC50 840.0 nM
NC(=O)COc1ccc(OCCn2ccnc2)cc1 CHEMBL423117 IC50 850.0 nM
Cc1c(Cc2cccnc2)cc2c(c1CCC(=O)O)CCC(NS(=O)(=O)c1ccc(Cl)cc1)C2 CHEMBL31409 IC50 850.0 nM
COc1cccc(OC)c1C(=O)NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21 CHEMBL439787 IC50 850.0 nM
CNC(=O)c1ccc(OCCn2ccnc2)cc1 CHEMBL286308 IC50 860.0 nM
CCCCCCn1cncc1[C@H]1OC(C)(C)OC[C@H]1C/C=C\CCC(=O)O CHEMBL17796 IC50 900.0 nM
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 CHEMBL83 IC50 916.0 nM
CC(C)C/N=C(\Nc1cccc(/C(=C\CCCC(=O)O)c2cccnc2)c1)Nc1nn[nH]n1 CHEMBL421854 IC50 930.0 nM
COc1ccc(S(=O)(=O)NCC(CCCCCC(=O)O)c2cccnc2)cc1 CHEMBL544148 IC50 940.0 nM
CC(=O)OCCCCCC(C1=C(C)C(=O)C(C)=C(C)C1=O)c1cccnc1 CHEMBL92247 IC50 950.0 nM
Cc1ccccc1-c1ccc(-c2ccc3c(c2)c(C)c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)cc1F CHEMBL180650 IC50 950.0 nM
Cc1c(Cc2cccnc2)cc2c(c1/C=C\CCCC(=O)O)CCC(NS(=O)(=O)c1ccc(Cl)cc1)C2 CHEMBL28848 IC50 960.0 nM
CC1=C(CCC(=O)O)C(=O)C(C)=C(Cc2cccnc2)C1=O CHEMBL327426 IC50 970.0 nM
O=C(O)CCCC/C=C(/c1cccnc1)c1nccs1 CHEMBL98371 IC50 980.0 nM
CC(CCCc1cccnc1)NC(=O)c1ccc2nc3ccc(C(C)C)cc3c(=O)n2c1 CHEMBL1202755 IC50 1000.0 nM
O=C(O)C/C=C(\c1ccc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccnc1 CHEMBL340504 IC50 1000.0 nM
CCOC(=O)CCCCCCC(COCc1ccc(OC)cc1)Cn1ccnc1 CHEMBL412442 IC50 1000.0 nM
C/C(=C/c1ccc(Cn2ccnc2)n1C)C(=O)O CHEMBL170776 IC50 1000.0 nM
CCCCCC(O)CO[C@@H]1[C@@H](CCCCCCC(=O)O)[C@@H]2C[C@@H]1N=N2 CHEMBL3251056 IC50 1000.0 nM