CC1=C(CC(=O)c2sccc2Br)C(=O)c2ccccc2C1=O CHEMBL5220107 IC50 3.42 nM
O=C1c2cc(F)ccc2C(=O)c2c1nnn2-c1ccc(F)c(Cl)c1 CHEMBL4787695 IC50 4.0 nM
O[C@H](c1cc(Cl)cc2cncn12)C1CCCCC1 CHEMBL5203175 IC50 9.6 nM
O=C1c2ccc(F)cc2C(=O)c2c1nnn2-c1ccc(F)c(Cl)c1 CHEMBL4765090 IC50 10.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(F)c(Cl)c1 CHEMBL4756155 IC50 14.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(Cl)cc1 CHEMBL4780314 IC50 15.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL4747779 IC50 15.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(Cl)c(Cl)c1 CHEMBL4753714 IC50 18.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(Cl)c(F)c1 CHEMBL4791729 IC50 18.0 nM
OCCn1c2ccccc2c2cncn21 CHEMBL4434743 IC50 20.0 nM
OCCC1c2ccccc2-c2cncn21 CHEMBL4466645 IC50 20.0 nM
Fc1ccc2c(-c3ccc4[nH]nnc4c3)c[nH]c2c1 CHEMBL4862796 IC50 20.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1cccnc1 CHEMBL4798028 IC50 21.0 nM
CCNC1=C/C(=N\c2ccc(F)c(Cl)c2)c2cc(C(=O)O)[nH]c2C1=O CHEMBL4747079 IC50 25.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(-c2nnn[nH]2)cc1 CHEMBL4783665 IC50 25.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(C(F)(F)F)c(Cl)c1 CHEMBL4785841 IC50 25.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(Cl)nc1 CHEMBL4642346 IC50 25.0 nM
CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1CC(N)=O CHEMBL3947656 IC50 26.0 nM
C[C@H]1NS(=O)(=O)c2ccc(-c3c[nH]c4cc(F)ccc34)cc21 CHEMBL3941937 IC50 27.0 nM
Nc1oncc1-c1ccsc1 CHEMBL4173485 IC50 28.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1cccc([N+](=O)[O-])c1 CHEMBL4777219 IC50 28.0 nM
Nc1oncc1-c1cccs1 CHEMBL4165554 IC50 29.0 nM
O[C@@H](c1cn2cncc2cc1Cl)C1CCCCC1 CHEMBL5218853 IC50 29.0 nM
Fc1ccc2c(/C=C/c3cccnc3)c[nH]c2c1 CHEMBL355606 Ki 30.0 nM
CN1CCN(C(=O)c2cccc(Cn3nnc4c3C(=O)c3ccccc3C4=O)c2)CC1 CHEMBL3628599 IC50 30.0 nM
CN1CCN(C(=O)c2ccc(Cn3nnc4c3C(=O)c3ccccc3C4=O)cc2)CC1 CHEMBL3628602 IC50 30.0 nM
O=C(O)/C=C/c1ccc2nc3n(c(=O)c2c1)-c1ccc(F)cc1C3=O CHEMBL4645973 IC50 30.0 nM
OC(CC1c2ccccc2-c2cncn21)C1CCCCC1 CHEMBL3629569 IC50 30.0 nM
O[C@@H]1c2ccccc2CC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4577396 EC50 32.0 nM
c1ccc2c(c1)-c1cncn1[C@H]2C1CCCCC1 CHEMBL4468203 EC50 33.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1cc(Cl)c(F)c(Cl)c1 CHEMBL4753565 IC50 34.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc2ccncc2c1 CHEMBL4763934 IC50 34.0 nM
NC(=O)c1ccc2c(c1)[C@@H](O)[C@H]([C@H]1c3ccccc3-c3cncn31)CC2 CHEMBL4544695 EC50 35.0 nM
O[C@@H]1CC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4555603 EC50 36.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1cccc(Cl)c1 CHEMBL4749726 IC50 36.0 nM
CS(=O)(=O)c1ccc2c(c1)[C@@H](O)[C@H]([C@H]1c3ccccc3-c3cncn31)CC2 CHEMBL4520696 EC50 39.0 nM
O=C1c2cc([N+](=O)[O-])ccc2-n2c1nc1ccccc1c2=O CHEMBL432537 IC50 40.0 nM
O[C@@H]1CCCC[C@H]1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5219865 IC50 40.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc2[nH]ncc2c1 CHEMBL4783159 IC50 42.0 nM
O=S1(=O)NC(CO)c2cc(-c3c[nH]c4cc(F)ccc34)ccc21 CHEMBL3913964 IC50 43.0 nM
Cn1cc(-c2ccc(N3CCC([C@H]4c5c(F)cccc5-c5cncn54)CC3)cc2)cn1 CHEMBL4522927 IC50 47.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2Cc1cccc(C(=O)N2CCOCC2)c1 CHEMBL3628598 IC50 48.0 nM
O[C@@H]1c2ccncc2CC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4437257 EC50 48.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc([N+](=O)[O-])cc1 CHEMBL4741094 IC50 48.0 nM
NS(=O)(=O)c1ccc(-n2nnc3c2C(=O)c2ccccc2C3=O)cc1 CHEMBL4741069 IC50 48.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc(F)cc1 CHEMBL4748868 IC50 49.0 nM
NC(=O)Nc1ccc(-c2c[nH]c3cc(F)ccc23)cc1 CHEMBL5177466 IC50 49.0 nM
O[C@@H]1c2cnccc2CC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4447185 EC50 50.0 nM
O[C@@H]1CCCC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4445816 EC50 50.0 nM
c1ccc2c(-c3ccc4nonc4c3)c[nH]c2c1 CHEMBL5169552 IC50 51.0 nM
O=C1c2cc(Br)ccc2-n2c1nc1ccccc1c2=O CHEMBL72165 IC50 53.0 nM
O[C@@H]1c2nonc2CC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4590789 EC50 54.0 nM
CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1CC1(C)COC(=O)N1 CHEMBL3975938 IC50 58.0 nM
COC(=O)c1ccc(-n2nnc3c2C(=O)c2ccccc2C3=O)cc1 CHEMBL4762048 IC50 58.0 nM
CC(=O)N1CCN(C(=O)c2cccc(Cn3nnc4c3C(=O)c3ccccc3C4=O)c2)CC1 CHEMBL3628597 IC50 59.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(F)cc1c2=O CHEMBL3087009 IC50 59.0 nM
N#Cc1ccc2c(c1)[C@@H](O)[C@H]([C@H]1c3ccccc3-c3cncn31)CC2 CHEMBL4541824 EC50 60.0 nM
OCCC1c2ccccc2-n2cncc21 CHEMBL4443553 IC50 60.0 nM
CN(C)Cc1ccc2nc3n(c(=O)c2c1)-c1ccc(F)cc1C3=O CHEMBL4452150 IC50 60.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccccc1c2=O CHEMBL1098875 IC50 60.0 nM
O=Cc1ccc2nc3n(c(=O)c2c1)-c1ccc(F)cc1C3=O CHEMBL4643029 IC50 60.0 nM
Cc1ccc(CNc2cc(C(F)(F)F)cc3[nH]ncc23)c([N+](=O)O)c1 CHEMBL5207789 IC50 60.0 nM
CN(C)CCc1ccc2nc3n(c(=O)c2c1)C1C=CC(F)=CC1C3=O CHEMBL5417450 IC50 60.0 nM
O=C1c2nc3ccccc3c(=O)n2C2C=CC([N+](=O)O)=CC12 CHEMBL5423304 IC50 61.0 nM
C[C@H]([C@H](O)C1CCCCC1)[C@H]1c2ccccc2-c2cncn21 CHEMBL4593111 EC50 62.0 nM
Cc1cccc(-n2nnc3c2C(=O)c2ccccc2C3=O)c1 CHEMBL4756754 IC50 64.0 nM
CS(=O)(=O)c1ccc2c(c1)CC[C@@H]([C@H]1c3ccccc3-c3cncn31)[C@@H]2O CHEMBL4539108 EC50 65.0 nM
Cn1cc(-c2ccc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)cc2F)cn1 CHEMBL4445809 IC50 65.0 nM
N#Cc1ccc(-n2nnc3c2C(=O)c2ccccc2C3=O)cc1 CHEMBL4752502 IC50 66.0 nM
O[C@@H]1CCC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4531114 EC50 70.0 nM
CC(C)(C)OC(=O)N1CCN(Cc2ccc3nc4n(c(=O)c3c2)-c2ccc(F)cc2C4=O)CC1 CHEMBL4577825 IC50 70.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(CN3CCOCC3)cc1c2=O CHEMBL4588805 IC50 70.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccccc1 CHEMBL4300931 IC50 70.0 nM
c1ccc2c(-c3ccc4ccncc4c3)c[nH]c2c1 CHEMBL4852583 IC50 70.0 nM
O=C1c2nc3ccc(CCN4CCOCC4)cc3c(=O)n2C2C=CC(F)=CC12 CHEMBL5437117 IC50 70.0 nM
CNC(=O)CCN1C(C)c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S1(=O)=O CHEMBL3937796 IC50 71.0 nM
CC(C)([C@H](O)c1ncco1)[C@H]1c2ccccc2-c2cncn21 CHEMBL4467673 EC50 71.0 nM
O=C(O)c1cccc(-n2nnc3c2C(=O)c2ccccc2C3=O)c1 CHEMBL4648447 IC50 71.0 nM
O[C@@H]1COCC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4548068 EC50 72.0 nM
O=C1c2ccccc2C(=O)c2[nH]c(-c3cscn3)nc21 CHEMBL4293312 IC50 73.1 nM
Nc1oncc1-n1cc(F)cn1 CHEMBL4166624 EC50 77.0 nM
Cn1cc(-c2ccc(NC(N)=O)cc2)c2ccc(F)cc21 CHEMBL5219853 IC50 78.0 nM
c1ccc2c(-c3cnc4nsnc4c3)c[nH]c2c1 CHEMBL5201313 IC50 82.0 nM
Nc1oncc1-c1ccccc1 CHEMBL4166415 EC50 85.0 nM
Fc1cccc2c1C(C1CCCCC1)n1cncc1-2 CHEMBL4586507 IC50 85.0 nM
CS(=O)(=O)N1CC[C@@H]([C@H]2c3ccccc3-c3cncn32)[C@H](O)C1 CHEMBL4542307 EC50 87.0 nM
CCN(CC)C(=O)c1cccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)c1 CHEMBL3628595 IC50 90.0 nM
CN1CCN(Cc2ccc3nc4n(c(=O)c3c2)-c2ccc(F)cc2C4=O)CC1 CHEMBL4437046 IC50 90.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(CN3CCNCC3)cc1c2=O CHEMBL4436480 IC50 90.0 nM
O[C@H]1CCCC[C@@H]1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5220396 IC50 90.0 nM
CN1CCN(CCc2ccc3nc4n(c(=O)c3c2)C2C=CC(F)=CC2C4=O)CC1 CHEMBL5427485 IC50 90.0 nM
c1ccc2c(-c3ccc4n[se]nc4c3)c[nH]c2c1 CHEMBL5185564 IC50 94.0 nM
Fc1cccc2c1C(C1CCCC1)n1cncc1-2 CHEMBL4524854 IC50 95.0 nM
c1ccc2c(-c3ccc4cnccc4c3)c[nH]c2c1 CHEMBL4850288 IC50 100.0 nM
c1ccc2c(-c3ccc4nnn(CC5CC5)c4c3)c[nH]c2c1 CHEMBL4868822 IC50 100.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1cccc(F)c1 CHEMBL4759518 IC50 101.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1ccc2[nH]cnc2c1 CHEMBL4750649 IC50 104.0 nM
COc1ccc2c(c1)C(=O)c1nnn(-c3ccc(F)c(Cl)c3)c1C2=O CHEMBL4786114 IC50 105.0 nM
CC1(C)C(=O)C=Cc2c1ccc1c2C(=O)C(=O)c2c(CCl)coc2-1 CHEMBL5174722 IC50 110.0 nM
Cc1cc(N2CCC(C3c4c(F)cccc4-c4cncn43)CC2)ccc1-c1cnn(C)c1 CHEMBL4443301 IC50 114.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2Cc1ccc(C(=O)N2CCOCC2)cc1 CHEMBL3628601 IC50 116.0 nM
OC1CCCCC1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5220677 IC50 120.0 nM
c1ccc2c(-c3ccc4nsnc4c3)c[nH]c2c1 CHEMBL5195880 IC50 129.0 nM
CP(C)(=O)c1ccc2c(c1)[C@@H](O)[C@H]([C@H]1c3ccccc3-c3cncn31)CC2 CHEMBL4589215 EC50 130.0 nM
O[C@@H]1c2ccnn2CC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4439294 EC50 130.0 nM
O[C@@H]1CCCC[C@H]1CNc1cc(Cl)cc2[nH]ncc12 CHEMBL5218595 IC50 130.0 nM
Cn1cc(-c2ccc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)cc2)cn1 CHEMBL4459856 IC50 132.0 nM
CC(=O)Nc1cccc(-n2nnc3c2C(=O)c2ccccc2C3=O)c1 CHEMBL4763470 IC50 132.0 nM
O[C@H](C[C@H]1c2c(F)cccc2-c2cncn21)[C@H]1CC[C@H](O)CC1 CHEMBL3989951 IC50 140.0 nM
O=C1c2ccccc2-n2c1nc1ccccc1c2=O CHEMBL306946 IC50 140.0 nM
CCN(CC)C(=O)Cc1ccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)cc1 CHEMBL3628604 IC50 145.0 nM
CC(=O)OCc1coc2c1C(=O)C(=O)c1c-2ccc2c1C=CC(=O)C2(C)C CHEMBL5204091 IC50 160.0 nM
O=C(O)c1cccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)c1 CHEMBL3628593 IC50 167.0 nM
CN1CCN(c2ccc3nc4n(c(=O)c3c2)-c2ccc(F)cc2C4=O)CC1 CHEMBL4536439 Ki 170.0 nM
c1ccc2c(-c3ccc4n[nH]nc4c3)c[nH]c2c1 CHEMBL4862463 IC50 170.0 nM
O=[N+](O)c1c(Cl)cccc1CNc1cc(C(F)(F)F)cc2[nH]ncc12 CHEMBL5197972 IC50 170.0 nM
O=C1c2cc(O)ccc2C(=O)c2c1nnn2-c1ccc(F)c(Cl)c1 CHEMBL4751532 IC50 171.0 nM
c1ccc2c(-c3cnc4n[se]nc4c3)c[nH]c2c1 CHEMBL5194281 IC50 171.0 nM
CC(=O)N1CCN(C(=O)c2ccc(Cn3nnc4c3C(=O)c3ccccc3C4=O)cc2)CC1 CHEMBL3628600 IC50 176.0 nM
CN1CCN(Cc2ccc3nc4n(c(=O)c3c2)-c2ccccc2C4=O)CC1 CHEMBL4545004 IC50 180.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(CN3CCCC3C(=O)O)cc1c2=O CHEMBL4647345 IC50 180.0 nM
CCN(CC)C(=O)c1ccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)cc1 CHEMBL3628596 IC50 181.0 nM
Fc1cccc2c1C(C1CCN(c3ccc(-c4cccnc4)cc3)CC1)n1cncc1-2 CHEMBL4435524 IC50 183.0 nM
Cc1ccc2c(c1)C(=O)c1nc3ccccc3c(=O)n1-2 CHEMBL312537 IC50 184.0 nM
Fc1cccc2c1C(C1CCOCC1)n1cncc1-2 CHEMBL4549778 IC50 189.0 nM
CNc1oncc1-c1ccccc1 CHEMBL4162962 IC50 190.0 nM
FC(F)(F)Cn1nnc2ccc(-c3c[nH]c4ccccc34)cc21 CHEMBL4871568 IC50 190.0 nM
CC(=O)O[C@@H]1CCCC[C@H]1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5220436 IC50 190.0 nM
Fc1cccc2c1C(C1CCN(c3nc4ccccc4s3)CC1)n1cncc1-2 CHEMBL4553360 IC50 195.0 nM
CC1(C)C(=O)CCc2c1ccc1c2C(=O)C(=O)c2c(CO)coc2-1 CHEMBL5172374 IC50 200.0 nM
COC1CCN(C(=O)c2ccc(Cn3nnc4c3C(=O)c3ccccc3C4=O)cc2)CC1 CHEMBL3628603 IC50 209.0 nM
Nc1oncc1-c1ccc(F)cc1 CHEMBL4170773 EC50 210.0 nM
O[C@@H]1CCOC[C@H]1[C@H]1c2ccccc2-c2cncn21 CHEMBL4540245 EC50 210.0 nM
O=C1c2ncccc2C(=O)c2sc(-c3cscn3)nc21 CHEMBL4291792 IC50 214.5 nM
Cn1cc(-c2ccc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)c(F)c2)cn1 CHEMBL4471614 IC50 215.0 nM
Cl[C@H]1CCCC[C@H]1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5218978 IC50 220.0 nM
Cc1cc(-c2cnn(C)c2)ccc1N1CCC(C2c3c(F)cccc3-c3cncn32)CC1 CHEMBL4521716 IC50 226.0 nM
O=C1c2c(Cl)cccc2-n2c1nc1ccccc1c2=O CHEMBL3087010 IC50 227.0 nM
Nc1oncc1-n1cccn1 CHEMBL4168975 EC50 230.0 nM
Fc1ccc2c(-c3ccc4nnn(CCN5CCNCC5)c4c3)c[nH]c2c1 CHEMBL4875970 IC50 230.0 nM
O=C1c2ccccc2-n2c1nc1ccc(F)cc1c2=O CHEMBL3086870 IC50 241.0 nM
NS(=O)(=O)NCCNc1nonc1/C(=N/O)Nc1ccc(F)c(Br)c1 CHEMBL3545369 IC50 242.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2-c1cnc(Cl)c(Cl)c1 CHEMBL4762733 IC50 248.0 nM
Nc1oncc1-c1cccc(Cl)c1 CHEMBL4170344 EC50 250.0 nM
O[C@@H](C[C@H]1c2ccccc2-c2cncn21)C1CCCCC1 CHEMBL3752060 EC50 250.0 nM
Nc1nnsc1-c1ccccc1 CHEMBL4174655 IC50 270.0 nM
CN(C)c1ccc2nc3n(c(=O)c2c1)-c1ccc(F)cc1C3=O CHEMBL4468741 IC50 270.0 nM
c1ccc2c(-c3ccc4ncncc4c3)c[nH]c2c1 CHEMBL4857329 IC50 270.0 nM
Nc1cc(Br)cc2[nH]ncc12 CHEMBL5219838 Ki 280.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(N3CCNCC3)cc1c2=O CHEMBL4471831 IC50 290.0 nM
COC(=O)C1CCCN1Cc1ccc2nc3n(c(=O)c2c1)-c1ccc(F)cc1C3=O CHEMBL4646483 IC50 300.0 nM
CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1CCS(N)(=O)=O CHEMBL3967430 IC50 309.0 nM
O=C(O)c1ccc(Cn2nnc3c2C(=O)c2ccccc2C3=O)cc1 CHEMBL3628594 IC50 312.0 nM
O=C1c2cccnc2C(=O)c2sc(-c3cscn3)nc21 CHEMBL4281167 IC50 321.5 nM
OCC(Nc1cc(Br)cc2[nH]ncc12)c1ccccc1 CHEMBL5219702 IC50 330.0 nM
Fc1cccc2c1C(C1CCN(c3ccccc3)CC1)n1cncc1-2 CHEMBL4470496 IC50 338.0 nM
Cc1cnn(-c2cnoc2N)c1 CHEMBL4177244 EC50 340.0 nM
Fc1cccc2c1C(C1CCN(c3ccc(-c4ccncc4)cc3)CC1)n1cncc1-2 CHEMBL4561893 IC50 353.0 nM
Nc1oncc1C1CCCC1 CHEMBL4166941 EC50 360.0 nM
N[C@@H]1CCCC[C@H]1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5219595 IC50 360.0 nM
CCOC(=O)/C=C/c1ccc2nc3n(c(=O)c2c1)-c1ccc(F)cc1C3=O CHEMBL4648181 IC50 370.0 nM
CC(=O)O[C@H]1CCc2c(ccc3c2C(=O)C(=O)c2c(C)coc2-3)C1(C)C CHEMBL5176219 IC50 370.0 nM
Fc1cccc(N2CCC(C3c4c(F)cccc4-c4cncn43)CC2)c1 CHEMBL4567552 IC50 371.0 nM
Fc1cccc2c1C(c1ccccc1)n1cncc1-2 CHEMBL4531639 IC50 374.0 nM
Cn1ccc2ccc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)cc21 CHEMBL4562566 IC50 376.0 nM
Cn1ncc2c1CC[C@@H]([C@H]1c3ccccc3-c3cncn31)[C@@H]2O CHEMBL4440730 EC50 380.0 nM
Cn1nnc2cc(-c3c[nH]c4ccccc34)ccc21 CHEMBL4863714 IC50 380.0 nM
O=C1c2ccc(O)cc2C(=O)c2c1nnn2-c1ccc(F)c(Cl)c1 CHEMBL4747007 IC50 384.0 nM
Oc1ccc(CNc2cc(Br)cc3[nH]ncc23)cc1 CHEMBL3972619 Ki 390.0 nM
N#Cc1ccc(N2CCC(C3c4c(F)cccc4-c4cncn43)CC2)cc1 CHEMBL4463063 IC50 394.0 nM
Fc1ccc2c(/C=C/c3nnn[nH]3)c[nH]c2c1 CHEMBL1812545 IC50 398.0 nM
c1ccc2c(-c3cnc4[nH]nnc4c3)c[nH]c2c1 CHEMBL4850064 IC50 400.0 nM
O[C@@H]1CCCC[C@H]1CNc1cc(C(F)(F)F)cc2[nH]ncc12 CHEMBL5219170 IC50 400.0 nM
c1ccc2c(-c3ccc4nnn(CC5CCOC5)c4c3)c[nH]c2c1 CHEMBL4871428 IC50 410.0 nM
Cc1cc(NC[C@@H]2CCCC[C@H]2O)c2cn[nH]c2c1 CHEMBL5220129 IC50 410.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(CN3CCCC(C(=O)O)C3)cc1c2=O CHEMBL4633682 IC50 420.0 nM
Nc1c(-c2c[nH]c3ccccc23)ccc2[nH]nnc12 CHEMBL4858642 IC50 420.0 nM
FC(F)(F)Cn1nnc2cc(-c3c[nH]c4ccccc34)ccc21 CHEMBL4853909 IC50 440.0 nM
O=C1c2cc(F)ccc2-n2c1nc1ccc(CN3CCC(C(=O)O)CC3)cc1c2=O CHEMBL4646657 IC50 450.0 nM
CC1(C)CCCc2c1ccc1c2C(=O)C(=O)c2c(CO)coc2-1 CHEMBL578036 IC50 450.0 nM
CC1(C)C(=O)C=Cc2c1ccc1c2C(=O)C(=O)c2c(CO)coc2-1 CHEMBL4751204 IC50 450.0 nM
CC1(C)CN(c2cc(Br)cc3[nH]ncc23)CCN1S(C)(=O)=O CHEMBL5219380 IC50 450.0 nM
ON=C1CCC(CNc2cc(Br)cc3[nH]ncc23)CC1 CHEMBL5218511 IC50 450.0 nM
FC(F)(F)c1cc(NC[C@H]2CCCCN2)c2cn[nH]c2c1 CHEMBL5196865 IC50 460.0 nM
O=[N+]([O-])c1ccc(O)cc1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5174721 IC50 460.0 nM
CN1CCN(c2ccc3nc4n(c(=O)c3c2)-c2ccccc2C4=O)CC1 CHEMBL4471895 IC50 470.0 nM
c1ccc2c(-c3ccc4cncnc4c3)c[nH]c2c1 CHEMBL4847184 IC50 490.0 nM
Nc1oc2cnccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4288032 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(F)cc1 CHEMBL4277115 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(C(F)(F)F)cc1 CHEMBL4279587 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccc(Cl)c1 CHEMBL4289482 IC50 500.0 nM
COc1cc(Nc2c(N)oc3cnccc23)ccc1Cl CHEMBL4290511 IC50 500.0 nM
Cc1ccc(Nc2c(N)oc3cnccc23)cc1C CHEMBL4277452 IC50 500.0 nM
Cc1cc(C)cc(Nc2c(N)oc3cnccc23)c1 CHEMBL4280494 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(Cl)c(Cl)c1 CHEMBL4281552 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(Br)cc1 CHEMBL4286518 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(Cl)cc1 CHEMBL4287546 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(I)c(Cl)c1 CHEMBL4281024 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccc(I)c1 CHEMBL4285144 IC50 500.0 nM
Cc1ccc(Nc2c(N)oc3cnccc23)cc1Br CHEMBL4278848 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(Cc2ccccc2)cc1 CHEMBL4282272 IC50 500.0 nM
COc1ccc(Cl)cc1Nc1c(N)oc2cnccc12 CHEMBL4283091 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccc(C(F)(F)F)c1 CHEMBL4278645 IC50 500.0 nM
Cc1cc(Nc2c(N)oc3cnccc23)ccc1F CHEMBL4277636 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(F)cc1Cl CHEMBL4291358 IC50 500.0 nM
CC(C)(C)c1cc(Nc2c(N)oc3cnccc23)cc(C(C)(C)C)c1 CHEMBL4281087 IC50 500.0 nM
Cc1ccc(Nc2c(N)oc3cnccc23)cc1Cl CHEMBL4287297 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc2c(c1)OCO2 CHEMBL4288676 IC50 500.0 nM
C#Cc1ccc(Nc2c(N)oc3cnccc23)cc1 CHEMBL4294844 IC50 500.0 nM
N#Cc1ccc(Nc2c(N)oc3cnccc23)cc1 CHEMBL4286735 IC50 500.0 nM
Cc1ccc(Nc2c(N)oc3cnccc23)cc1 CHEMBL4291859 IC50 500.0 nM
CC(=O)c1ccc(Nc2c(N)oc3cnccc23)cc1 CHEMBL4288159 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(F)c(Cl)c1F CHEMBL4289501 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccc(F)c1 CHEMBL4293556 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cc(Cl)c(F)c(Cl)c1 CHEMBL4292539 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccnc1 CHEMBL4277566 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(OC(F)(F)F)cc1 CHEMBL4290983 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cncc(Cl)c1 CHEMBL4294746 IC50 500.0 nM
Cc1ccc(Nc2c(N)oc3cnccc23)c(C)c1 CHEMBL4293330 IC50 500.0 nM
Nc1oc2cncc(Cl)c2c1Nc1ccc(Cl)c(F)c1 CHEMBL4278347 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(F)c(F)c1 CHEMBL4279780 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1ccc(F)c(C(F)(F)F)c1 CHEMBL4279406 IC50 500.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2cn1 CHEMBL4277061 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccc(C(F)F)c1 CHEMBL4294575 IC50 500.0 nM
COc1cncc2oc(N)c(Nc3ccc(F)c(Cl)c3)c12 CHEMBL4284726 IC50 500.0 nM
C#Cc1cccc(Nc2c(N)oc3cnccc23)c1 CHEMBL4281187 IC50 500.0 nM
Cc1cc(Nc2c(N)oc3cnccc23)ccc1Cl CHEMBL4282590 IC50 500.0 nM
Cc1ncc(C)c2c(Nc3ccc(F)c(Cl)c3)c(N)oc12 CHEMBL4278779 IC50 500.0 nM
CCc1nccc2c(Nc3cccc(C(F)(F)F)c3)c(N)oc12 CHEMBL4286058 IC50 500.0 nM
CCCc1nccc2c(Nc3ccc(F)c(C(F)(F)F)c3)c(N)oc12 CHEMBL4289945 IC50 500.0 nM
CC(C)c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12 CHEMBL4284439 IC50 500.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(C)n1 CHEMBL4285852 IC50 500.0 nM
Cc1cc(Cl)cc(Nc2c(N)oc3cnccc23)c1 CHEMBL4277163 IC50 500.0 nM
Nc1oc2cnccc2c1Nc1cccc(C2CCCCC2)c1 CHEMBL4288607 IC50 500.0 nM
COc1cccc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)c1 CHEMBL4287189 IC50 500.0 nM
C#Cc1cccc(Nc2c(N)oc3c(C)nccc23)c1 CHEMBL4279234 IC50 500.0 nM
C#Cc1cccc(Nc2c(N)oc3c(CC)nccc23)c1 CHEMBL4283761 IC50 500.0 nM
COc1ccccc1-c1nccc2c(Nc3ccc(F)c(Cl)c3)c(N)oc12 CHEMBL4292762 IC50 500.0 nM
CC(C)(C)Oc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(-c2ccccc2)n1 CHEMBL4289829 IC50 500.0 nM
Nc1oc2c(C3CCCCC3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4285043 IC50 500.0 nM
C#Cc1cc(Nc2c(N)oc3c(-c4ccccc4)nccc23)ccc1F CHEMBL4294480 IC50 500.0 nM
C#Cc1cc(Nc2c(N)oc3c(-c4ccncc4)nccc23)ccc1F CHEMBL4276969 IC50 500.0 nM
N#Cc1ccc2c(Nc3cccc(C(F)(F)F)c3)c(N)oc2c1 CHEMBL4278098 IC50 500.0 nM
Nc1sc2ccc(Cl)cc2c1Nc1ccc(F)cc1 CHEMBL4293178 IC50 500.0 nM
Nc1sc2ccc(Cl)cc2c1Nc1cccc(C(F)(F)F)c1 CHEMBL4278716 IC50 500.0 nM
Cc1cccc(Nc2c(N)sc3ccccc23)c1C CHEMBL4291105 IC50 500.0 nM
O=C(Nc1oc2cnccc2c1Nc1ccc(F)c(Cl)c1)OCc1ccccc1 CHEMBL4292556 IC50 500.0 nM
Nc1oc2c(-c3ccc(F)cc3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4282826 IC50 500.0 nM
Cn1cc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)cn1 CHEMBL4288214 IC50 500.0 nM
N#Cc1ccc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)cc1 CHEMBL4287152 IC50 500.0 nM
NC(=O)c1ccc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)cc1 CHEMBL4294302 IC50 500.0 nM
COC(=O)c1ccc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)cc1 CHEMBL4289072 IC50 500.0 nM
N#Cc1nccc2c(Nc3ccc(F)c(Cl)c3)c(NC(=O)OCc3ccccc3)oc12 CHEMBL4286487 IC50 500.0 nM
Cc1cc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)ccn1 CHEMBL4282298 IC50 500.0 nM
COc1cc2c(Nc3ccc(F)c(Cl)c3)c(N)oc2c(-c2ccc(F)cc2)n1 CHEMBL4290549 IC50 500.0 nM
Nc1oc2cnc(Cl)cc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4290911 IC50 500.0 nM
Nc1oc2cc([N+](=O)[O-])ccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4283317 IC50 500.0 nM
Nc1oc2c(-c3ccncc3)nc(F)cc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4282281 IC50 500.0 nM
N#Cc1nccc2c(Nc3ccc(F)c(C(F)(F)F)c3)c(N)oc12 CHEMBL4283286 IC50 500.0 nM
N#Cc1nccc2c(Nc3cc(F)cc(F)c3)c(N)oc12 CHEMBL4280522 IC50 500.0 nM
Nc1oc2c(-c3ccncc3)nc(F)cc2c1Nc1ccc(F)c(F)c1 CHEMBL4287133 IC50 500.0 nM
Nc1oc2c(F)nccc2c1Nc1ccc(F)c(C(F)(F)F)c1 CHEMBL4286734 IC50 500.0 nM
Nc1oc2c(F)nc(F)cc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4287789 IC50 500.0 nM
Nc1oc2c(-c3cc(F)nc(F)c3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4294038 IC50 500.0 nM
Nc1oc2c(-c3ccncc3)nccc2c1Nc1ccc(F)c(C(F)(F)F)c1 CHEMBL4279627 IC50 500.0 nM
CNC(=O)c1cc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)ccn1 CHEMBL4281007 IC50 500.0 nM
Nc1oc2c(-c3ccncc3)nccc2c1Nc1ccccc1Cl CHEMBL4285861 IC50 500.0 nM
Nc1oc2c(-c3ccncc3)nccc2c1Nc1cccc(C(F)(F)F)c1 CHEMBL4280727 IC50 500.0 nM
Cc1cc(-c2nccc3c(Nc4ccc(F)c(C(F)(F)F)c4)c(N)oc23)ccn1 CHEMBL4295250 IC50 500.0 nM
Cc1cc(-c2nccc3c(Nc4ccccc4Cl)c(N)oc23)ccn1 CHEMBL4280350 IC50 500.0 nM
Cc1cc(-c2nccc3c(Nc4cccc(C(F)(F)F)c4)c(N)oc23)ccn1 CHEMBL4293768 IC50 500.0 nM
Nc1sc2c(Br)cccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4288820 IC50 500.0 nM
Nc1sc2c(-c3ccncc3)cccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4279698 IC50 500.0 nM
Nc1oc2cnc(F)cc2c1Nc1ccccc1Cl CHEMBL4284653 IC50 500.0 nM
CNC(=O)c1cc(-c2nccc3c(Nc4ccccc4Cl)c(N)oc23)ccn1 CHEMBL4291240 IC50 500.0 nM
Nc1oc2cnc(F)cc2c1Nc1cccc(C(F)(F)F)c1 CHEMBL4278281 IC50 500.0 nM
CNC(=O)c1cc(-c2nccc3c(Nc4ccc(F)c(F)c4)c(N)oc23)ccn1 CHEMBL4282402 IC50 500.0 nM
CNC(=O)c1cc(-c2nccc3c(Nc4cccc(Cl)c4)c(N)oc23)ccn1 CHEMBL4290668 IC50 500.0 nM
COc1cc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)ccn1 CHEMBL4284125 IC50 500.0 nM
Nc1sc2ccccc2c1Nc1cccc(Br)c1 CHEMBL4283101 IC50 500.0 nM
Cc1cc(-c2nccc3c(Nc4cccc(Cl)c4)c(N)oc23)ccn1 CHEMBL4285170 IC50 500.0 nM
Cc1cc(-c2nc(F)cc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)ccn1 CHEMBL4279026 IC50 500.0 nM
Nc1oc2c(N3CCOCC3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4281858 IC50 500.0 nM
Cc1cc(-c2nc(F)cc3c(Nc4ccc(F)c(F)c4)c(N)oc23)ccn1 CHEMBL4280768 IC50 500.0 nM
Cc1cc(-c2cccc3c(Nc4cccc(Cl)c4)c(N)sc23)ccn1 CHEMBL4276888 IC50 500.0 nM
Cc1cc(-c2nc(F)cc3c(Nc4cccc(Cl)c4)c(N)oc23)ccn1 CHEMBL4288369 IC50 500.0 nM
Nc1oc2c[n+]([O-])ccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4277466 IC50 500.0 nM
Nc1oc2c(-c3ccc4c(c3)OCO4)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4278469 IC50 500.0 nM
CCc1cc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)ccn1 CHEMBL4286554 IC50 500.0 nM
Cc1cc(-c2cccc3c(Nc4ccccc4)c(N)sc23)ccn1 CHEMBL4286928 IC50 500.0 nM
Cc1cc(-c2cccc3c(Nc4ccc(F)cc4)c(N)sc23)ccn1 CHEMBL4292046 IC50 500.0 nM
Nc1oc2c(-c3ccnc(C(=O)N4CCCCC4)c3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4292367 IC50 500.0 nM
Nc1oc2c(-c3ccnc(C(=O)N4CCOCC4)c3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4291312 IC50 500.0 nM
Nc1oc2c(-c3ccnc(C(=O)NCCN4CCOCC4)c3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4285660 IC50 500.0 nM
Nc1oc2c(-c3cc(F)ccc3Cl)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4281561 IC50 500.0 nM
Cc1cc(C)cc(-c2nccc3c(Nc4ccc(F)c(Cl)c4)c(N)oc23)c1 CHEMBL4284269 IC50 500.0 nM
Nc1oc2c(-c3cc(F)cc(F)c3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4280130 IC50 500.0 nM
Nc1oc2c(/C=C/c3ccccc3)nccc2c1Nc1ccc(F)c(Cl)c1 CHEMBL4283946 IC50 500.0 nM
O=C1c2ccccc2-n2c1nc1ccc(N3CCOCC3)cc1c2=O CHEMBL4584081 IC50 500.0 nM
c1ccc2c(-c3ccc4nnn(CC5CCCO5)c4c3)c[nH]c2c1 CHEMBL4873980 IC50 500.0 nM
O=[N+]([O-])c1c(-c2c[nH]c3ccccc23)ccc2nn[nH]c12 CHEMBL4863129 IC50 540.0 nM
Cc1ccccc1Cn1nnc2c1C(=O)c1ccccc1C2=O CHEMBL1442185 IC50 561.0 nM
CC1(C)C(=O)C=Cc2c1ccc1c2C(=O)C(=O)c2c(CF)coc2-1 CHEMBL5172044 IC50 570.0 nM
Cn1cc(-c2cnc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)nc2)cn1 CHEMBL4518260 IC50 579.0 nM
Fc1cccc2c1C(C1CCN(c3nccs3)CC1)n1cncc1-2 CHEMBL4441377 IC50 586.0 nM
c1ccc2c(-c3ccc4c(c3)nnn4CC3CCNC3)c[nH]c2c1 CHEMBL4854488 IC50 620.0 nM
Cn1cc(-c2cccc(N3CCC(C4c5c(F)cccc5-c5cncn54)CC3)c2)cn1 CHEMBL4585863 IC50 639.0 nM
CC(=O)OCc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCC(=O)C2(C)C CHEMBL5206950 IC50 670.0 nM
NC(=O)Cn1nnc2ccc(-c3c[nH]c4ccccc34)cc21 CHEMBL4867529 IC50 680.0 nM
O=C1c2ncccc2C(=O)c2sc(-c3ccncc3)nc21 CHEMBL4281581 IC50 684.3 nM
Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1C(Br)CCC2(C)C CHEMBL5193307 IC50 710.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2Cc1cccc(Cl)c1 CHEMBL3628551 IC50 711.0 nM
O=C1c2ccc(Cl)cc2-n2c1nc1ccccc1c2=O CHEMBL1276265 IC50 733.0 nM
c1ccc2c(-c3ccc4c(c3)nnn4CCN3CCNCC3)c[nH]c2c1 CHEMBL4863211 IC50 740.0 nM
OCC(O)Cn1nnc2cc(-c3c[nH]c4ccccc34)ccc21 CHEMBL4870875 IC50 750.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2Cc1cccc(Br)c1 CHEMBL3628554 IC50 768.0 nM
CS(=O)(=O)c1ccc(CNc2cc(C(F)(F)F)cc3[nH]ncc23)c([N+](=O)O)c1 CHEMBL5188603 IC50 790.0 nM
Fc1cccc2c1C(Cc1ccccc1)n1cncc1-2 CHEMBL4571179 IC50 793.0 nM
Cc1ccn(-c2cnoc2N)n1 CHEMBL4176841 EC50 810.0 nM
c1ccc2c(c1)[nH]c1c(-c3ccsc3)nccc12 CHEMBL39183 IC50 810.0 nM
Nc1oncc1-c1ccccn1 CHEMBL4165043 EC50 820.0 nM
Nc1oncc1-c1ccc(Cl)cc1 CHEMBL4160126 IC50 830.0 nM
O=C1NCC2C=CC(c3c[nH]c4ccccc34)=CC2N1 CHEMBL4863469 IC50 830.0 nM
O=C1c2ccccc2C(=O)c2c1nnn2Cc1ccccc1 CHEMBL1644447 IC50 858.0 nM
Brc1cc(NCC2CCCCC2)c2cn[nH]c2c1 CHEMBL5218714 IC50 860.0 nM
N[C@H]1CCCC[C@H]1CNc1cc(Br)cc2[nH]ncc12 CHEMBL5219723 IC50 910.0 nM
Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCC(=O)C2(C)C CHEMBL5199052 IC50 940.0 nM
CC1(C)c2ccc3c(c2CC[C@@H]1O)C(=O)C(=O)c1c(CO)coc1-3 CHEMBL5183281 IC50 950.0 nM
Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1C=CC(=O)C2(C)C CHEMBL5177245 IC50 960.0 nM
Cn1nnc2ccc(-c3c[nH]c4ccccc34)c(N)c21 CHEMBL4875453 IC50 970.0 nM
c1ccc2c(-c3ccc4c(c3)nnn4CC3CC3)c[nH]c2c1 CHEMBL4862820 IC50 980.0 nM
COC(=O)C1CCN(Cc2ccc3nc4n(c(=O)c3c2)-c2ccc(F)cc2C4=O)CC1 CHEMBL4645897 IC50 990.0 nM