CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 CHEMBL65 IC50 0.0 nM
C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2C[C@@H](O)[C@]2(C)[C@@H](C3=CC(=O)OC3)CC[C@]12O CHEMBL1153 Potency 0.1 nM
CC1(C)S[C@H]2[C@@H](N)C(=O)N2[C@H]1C(=O)O CHEMBL1612062 Potency 0.1 nM
O=C(O)[C@@H](O)[C@@H](O)[C@@H](O)[C@@H](O)C(=O)O CHEMBL1316755 Potency 0.2 nM
CCCN(C/C=C\I)[C@@H]1CCc2ccc(O)cc2C1 CHEMBL1552249 Potency 0.3 nM
CN/C(=N/C#N)NCCSC[C@H]1N=CN=C1C CHEMBL1437804 Potency 0.4 nM
c1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1256916 Potency 0.5 nM
CCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO CHEMBL448741 Potency 0.6 nM
CCOC(=O)c1ccc(OC(=O)CCCCCNC(=N)N)cc1 CHEMBL87563 Potency 0.7 nM
Clc1cccc(N2CCNCC2)c1 CHEMBL478 Potency 0.7 nM
CC(C)SC(=N)N CHEMBL483091 Potency 0.7 nM
CC(C)Oc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1 CHEMBL1317823 Potency 0.8 nM
CCN(Cc1ccncc1)C(=O)[C@@H](CO)c1ccccc1 CHEMBL1457550 Potency 0.8 nM
CC1=NN(c2ccccc2)C(=O)C1 CHEMBL290916 Potency 0.8 nM
O=C1CCCN1CC#CCN1CCCC1 CHEMBL7634 Potency 0.9 nM
CCCCCCCCCCCCC/C=C\[C@@H](O)[C@@H](N)CO CHEMBL1453208 Potency 0.9 nM
COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC CHEMBL29197 Potency 0.9 nM
Oc1ccc(/C=C\c2cc(O)cc(O)c2)cc1 CHEMBL87333 Potency 1.0 nM
CCN(CC)CCOCCOC(=O)C1(c2ccccc2)CCCC1 CHEMBL73234 Potency 1.0 nM
C[C@@H]1O[C@H](O[C@@H]2/C=C\C=C/C=C/C=C\C[C@H](C)OC(=O)/C=C\[C@H]3O[C@@H]3C[C@H](O)C[C@]3(O)C[C@@H](O)[C@@H](C(=O)O)[C@H](C2)O3)[C@@H](O)[C@H](N)[C@@H]1O CHEMBL1555076 Potency 1.8 nM
Cc1cc(C2CCCCC2)n(O)c(=O)c1 CHEMBL242580 Potency 1.8 nM
CCOc1ccc(Cc2nccc3cc(OCC)c(OCC)cc23)cc1OCC CHEMBL1555736 Potency 1.8 nM
CC[C@H](CC[C@H](C)[C@@H]1CC[C@@H]2[C@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]21C)C(C)C CHEMBL1398443 Potency 1.8 nM
C[C@@]12CCC(=O)C=C1C=C[C@H]1[C@H]3CC[C@](O)(CCC(=O)[O-])[C@]3(C)CC[C@@H]12 CHEMBL1603234 Potency 2.0 nM
CCN(CC)C(=O)N[C@H]1C=C2c3cccc4[nH]cc(c34)C[C@@H]2N(C)C1 CHEMBL189438 Potency 2.0 nM
O=C([O-])[C@@H](O)[C@@H](O)C(=O)O CHEMBL1356989 Potency 2.0 nM
CC(C)N(CC[C@@](C(N)=O)(c1ccccc1)c1ccccn1)C(C)C CHEMBL269362 Potency 2.2 nM
CNCCc1ccccn1 CHEMBL1451277 Potency 2.5 nM
Cc1cc(C)c(NC(=O)C[C@H](CC(=O)[O-])c2cccc3ccccc23)c(C(=O)N2CCC3(CCCC3)CC2)c1 CHEMBL1335406 Potency 3.2 nM
N[C@@H](Cn1oc(=O)[nH]c1=O)C(=O)O CHEMBL279956 Potency 3.5 nM
CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1 CHEMBL343633 Potency 4.0 nM
C#CCOCCOCCOCCNc1nc(N2CCN(C(=O)[C@H]([C@@H](C)CC)n3cc([C@@H](N)CO)nn3)CC2)nc(N2CCN(C(=O)[C@H]([C@@H](C)CC)n3cc([C@@H](N)CC(C)C)nn3)CC2)n1 CHEMBL1430739 Potency 4.0 nM
Cc1ccccc1N CHEMBL1579403 Potency 4.0 nM
CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL1889091 Potency 4.5 nM
O=C(O)CCCC[C@@H]1SC[C@H]2NC(=O)N[C@@H]12 CHEMBL1434820 Potency 4.5 nM
O=[N+]([O-])c1ccc(N2CCN(CC(O)COc3ccccc3)CC2)cc1 CHEMBL1489519 Potency 4.5 nM
O=C(Cn1c2ccccc2c(=O)c2ccccc21)Nc1ccccc1F CHEMBL1502833 Potency 5.0 nM
C=C(C)[C@H]1Cc2c(ccc3c2O[C@@H]2COc4cc(OC)c(OC)cc4[C@@H]2C3=O)O1 CHEMBL429023 Potency 5.0 nM
CC(COc1ccc(/C=C/c2ccccc2)cc1)[N+](C)(C)C CHEMBL1256914 Potency 5.0 nM
O=C(O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@@H]21 CHEMBL1612121 Potency 5.0 nM
O=C(O)[C@@H]1[C@@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL1613623 Potency 5.0 nM
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(CNc4ccc(S(=O)(=O)Nc5nc(C)cc(C)n5)cc4)CC3)cc21 CHEMBL4464463 IC50 5.0 nM
CC(=O)NCCc1c(Cc2ccccc2)[nH]c2ccccc12 CHEMBL286615 Potency 5.6 nM
O=C(Nc1nnc[nH]1)c1c(Cl)ccc(Cl)c1Cl CHEMBL394034 Potency 6.3 nM
CC12CCC3C(CCC4=C(O)C(=O)CCC43C)C1CCC2=O CHEMBL314699 Potency 6.3 nM
CC(C)Oc1cccnc1N(C)C1CCN(Cc2ccccc2)CC1 CHEMBL64119 Potency 7.1 nM
NC1(C(=O)O)CCc2cc(C(=O)O)ccc21 CHEMBL313938 Potency 7.1 nM
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nncs3)CC2)cc1 CHEMBL1383301 Potency 7.1 nM
Cn1cnc(CCN)c1 CHEMBL1487156 Potency 7.1 nM
COc1ccc(C(S)=NCS(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL1575506 Potency 7.9 nM
Cc1cc(C(=O)N/N=C/c2sc(N3CCOCC3)nc2-c2ccccc2)c(C)o1 CHEMBL1971767 Potency 7.9 nM
COc1ccc2c(c1)OC/C(=C\c1ccc(OC)c(O)c1)C2=O CHEMBL1489223 Potency 8.9 nM
O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21 CHEMBL1057 Potency 8.9 nM
COc1cc(CC(=O)O)ccc1O CHEMBL1562 Potency 8.9 nM
COc1ccc(C(C)(C)C)cc1NC(=O)COC(=O)c1ccc([N+](=O)[O-])o1 CHEMBL1348421 Potency 8.9 nM
Clc1ccc2c(c1)C(N1CCNCC1)=Nc1ccccc1O2 CHEMBL1113 Potency 10.0 nM
C=CCCCCCCCCCCCc1ccco1 CHEMBL1608830 Potency 10.0 nM
O=C(O)C1=C[C@H](c2ccccc2)C[C@H](OCc2ccc(CO)cc2)O1 CHEMBL1372222 Potency 10.0 nM
CCN(CC)CCC[C@H](C)Nc1ccnc2cc(Cl)ccc12 CHEMBL250447 Potency 10.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(/C=C(\C)CCC=C(C)C)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4746230 IC50 10.3 nM
Cc1cccc(Nc2ccccc2C(=O)O)c1C CHEMBL686 Potency 11.2 nM
Cc1cc(-c2ccccc2)nnc1NCCN1CCOCC1 CHEMBL278819 Potency 11.2 nM
CCCCc1cc2ccccc2c(OCCN(C)C)n1 CHEMBL127643 Potency 11.2 nM
Cc1cc(O)nc(N=N/C(=N/Nc2ccc(O)cc2)c2ccccc2)n1 CHEMBL3198603 Potency 11.2 nM
Cc1cnc(C(=O)N2CCc3c([nH]c4ccccc34)C2c2ccc(F)cc2)cn1 CHEMBL1462323 Potency 11.2 nM
O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O CHEMBL275938 IC50 12.0 nM
OCCNCCCOc1cccc(Cl)c1Cl CHEMBL1356094 Potency 12.6 nM
O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 CHEMBL857 Potency 12.6 nM
CCN(Cc1ccncc1)Cc1c(O)ccc2ccccc12 CHEMBL1409308 Potency 12.6 nM
COC(=O)C1C(O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)C3C[C@@H]12 CHEMBL1594925 Potency 12.6 nM
O=C1C2C(c3ccccc3)CC=CC2[C@H](c2ccoc2)N1Cc1ccccc1 CHEMBL1432358 Potency 12.6 nM
CC(C)(C)OC(=O)CNC(=O)c1[nH]cnc1C(=O)Nc1ccc(CNC(=O)OC(C)(C)C)cc1 CHEMBL1604180 Potency 12.6 nM
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)C[C@@H]4NC(=O)[C@H](Cc5ccccc5)NC4=O)c3)cc2C(F)(F)F)CC1 CHEMBL1390950 Potency 14.1 nM
Cc1cccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](Cc2ccccc2)C(=O)OC(C)(C)C)c1 CHEMBL1511193 Potency 14.1 nM
NC(=O)CC(NC(=O)Cc1cccc2ccccc12)c1ccc(NC2CCCCCCC2)c([N+](=O)[O-])c1 CHEMBL1304238 Potency 15.8 nM
NCC(O)(CS(=O)(=O)O)c1ccc(Cl)cc1 CHEMBL1256573 Potency 15.8 nM
Cc1ccc(N=C(S)NCCC(c2ccccc2)c2ccccc2)c(C)c1 CHEMBL1507020 Potency 15.8 nM
OC(COc1cccc2ccccc12)CN1CCN(c2ccccc2)CC1 CHEMBL1390226 Potency 15.8 nM
O=C(CN1C(=O)/C(=C\c2ccccc2F)SC1=S)Nc1nc2ccccc2s1 CHEMBL1319209 Potency 15.8 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/CC(C)CCC=C(C)C)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL5187480 IC50 16.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(CC(C)CCC=C(C)C)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4760174 IC50 16.4 nM
N=C(N)NC(=O)c1nc(Cl)c(N)nc1N CHEMBL540851 Potency 17.8 nM
Cc1ccc(S(=O)(=O)NNC(=O)C(=O)NNc2ccccn2)cc1 CHEMBL1345687 Potency 17.8 nM
CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5[C@H](O)C[C@]43C)C2C1 CHEMBL1494479 Potency 17.8 nM
Nc1ncnc2c1ncn2C1CCCC1 CHEMBL1416619 Potency 17.8 nM
O=C(NC(=S)NNC(=O)c1ccccc1F)c1cccnc1 CHEMBL1445375 Potency 17.8 nM
O=c1c2ccccc2[se]n1-c1ccccc1 CHEMBL51085 Potency 17.8 nM
COc1ccccc1NC(=O)c1c(Nc2ccccc2F)sc(C(=O)Nc2cccc(Cl)c2)c1N CHEMBL1329311 Potency 17.8 nM
O=C(OCC1O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL1500249 Potency 17.8 nM
O=C1NC(=O)N(CCc2ccccc2)C(=O)/C1=C/NNC(=O)c1ccncc1 CHEMBL1342581 Potency 17.8 nM
CCCNC(C)(C)COC(=O)c1ccccc1 CHEMBL127810 Potency 17.8 nM
CCN(CC)CCOC(=O)C1(C2CCCCC2)CCCCC1 CHEMBL1200479 Potency 20.0 nM
COc1ccc(-c2ccccc2)cc1NCc1ccc(OC)c(OC)c1 CHEMBL1607418 Potency 20.0 nM
O=C(N/N=C/c1ccc(O)cc1O)/C(=C/c1ccccc1)CCO CHEMBL1974180 Potency 20.0 nM
COCCNC(=O)C1(C(F)(F)F)C/C(=C\CCO)CCCO1 CHEMBL1570522 Potency 20.0 nM
COc1c(N2CCN(CNc3ccc(S(=O)(=O)Nc4nc(C)cc(C)n4)cc3)C(C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 CHEMBL4571632 IC50 22.0 nM
O=C(CCCC[C@@H]1SC[C@H]2NC(=O)N[C@H]12)Nc1ccc(C(=O)O)cc1 CHEMBL1555454 Potency 22.4 nM
COc1ccc(N/N=C/c2c(C(=O)O)ccc3ccccc23)cc1 CHEMBL3196134 Potency 22.4 nM
O=S(=O)(c1c(Cl)sc(Cl)c1Br)N1CCCC1 CHEMBL1539068 Potency 22.4 nM
CN(C)C/C=C(/c1ccc(Br)cc1)c1cccnc1 CHEMBL1257002 Potency 22.4 nM
Nc1nc(N)c2nc(CNc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cnc2n1 CHEMBL376180 Potency 22.4 nM
CCCc1nc(C(C)(C)O)c(C(=O)OCc2oc(=O)oc2C)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 CHEMBL1200692 Potency 22.4 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1cc(C(C)(C)C)cc(C(C)(C)C)c1O)C4=O CHEMBL4244758 IC50 25.0 nM
COC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21 CHEMBL1395982 Potency 25.1 nM
Cc1ccc(NC(=O)CC(c2ccc(F)cc2)N2Cc3ccccc3C2=O)cc1C CHEMBL1367674 Potency 25.1 nM
O=C(c1ccc(F)cc1)N1CCN(c2ccc([N+](=O)[O-])cc2-n2cccc2)CC1 CHEMBL1575619 Potency 25.1 nM
CC(C)(C)OC(=O)NCc1ccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](Cc2ccccc2)C(=O)OC(C)(C)C)cc1 CHEMBL1419873 Potency 25.1 nM
Cc1cc(C)cc(CC(Cc2nc3ccccc3[nH]2)c2nc3ccccc3[nH]2)c1 CHEMBL1556273 Potency 25.1 nM
O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(Br)s1 CHEMBL548615 Potency 25.1 nM
O=C(O)COCCN1CCN([C@@H](c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL1334217 Potency 25.1 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5ccc(Br)cc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4438274 IC50 26.0 nM
C=C(C)[C@H]1CC=C(/C=N\Nc2nc(-c3c(O)c(C)c(O)c4c3OC3=CC(O)=C(C(C)=O)C(=O)[C@@]34C)cs2)CC1 CHEMBL4799682 IC50 27.0 nM
OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL1496351 Potency 28.2 nM
CCCN(CCC)C(=O)Cc1ccc(F)cc1 CHEMBL1509325 Potency 28.2 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2c3cccc4c3c(cn4C)C[C@@H]21 CHEMBL1441920 Potency 28.2 nM
O=C1N[C@@H]2[C@H](CCCCC(=O)Oc3ccc([N+](=O)[O-])cc3)SC[C@H]2N1 CHEMBL1327973 Potency 28.2 nM
COc1cc2c(c(O)c1OC)-c1c(cc(OC)c(OC)c1OC)C[C@@H](C)[C@@H](C)C2 CHEMBL490125 Potency 28.2 nM
CCO[C@@H]1OC(C(=O)NCc2nc3ccccc3[nH]2)=C[C@H](c2cn(C(C)=O)c3ccccc23)[C@H]1CCCO CHEMBL1605320 Potency 28.2 nM
N=C(NC(=O)/C=C/c1ccccc1)Nc1nc2ccccc2o1 CHEMBL1528678 Potency 28.2 nM
N#CC(C#N)=Cc1ccc([N+](=O)[O-])c(O)c1 CHEMBL77387 Potency 28.2 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C5/C[C@H]6CC[C@]5(C)C6(C)C)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4756604 IC50 31.0 nM
COC/C=C/C1=CC2=CC(=O)C(C)(OC(=O)c3cnc4ccccc4n3)C(=O)C2=CN1Cc1ccccc1 CHEMBL1504850 Potency 31.6 nM
O=C(O)C[C@@H]1C(=O)O[C@@H]2C(COC(=O)c3cc(O)c(O)c(O)c3)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H]2OC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1391063 Potency 31.6 nM
COc1cc(CN2CCCC(C(=O)c3ccccc3SC)C2)cc(OC)c1 CHEMBL1352004 Potency 31.6 nM
CC1(COc2ccc(CC3SC(=O)NC3=O)cc2)CCCCC1 CHEMBL7002 Potency 31.6 nM
Oc1ccc2ccccc2c1/C=N/Cc1ccccc1 CHEMBL3190693 Potency 31.6 nM
C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c1ccnc2ccc(OC)cc12 CHEMBL1294 Potency 31.6 nM
CCCCC1=CC2=CC(=O)C(C)(OC(=O)C3CCCC3)C(=O)C2=CO1 CHEMBL1558644 Potency 31.6 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5ccc([N+](=O)[O-])cc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4440514 IC50 35.0 nM
COc1ccc2nc(Nc3nc4ccc(NC(C)=O)cc4s3)sc2c1 CHEMBL1366128 Potency 35.5 nM
NC(=O)c1ccccc1 CHEMBL267373 Potency 35.5 nM
O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O CHEMBL1448 Potency 39.8 nM
CN(c1ccccc1)S(=O)(=O)c1cccc(C(=O)Nc2nccs2)c1 CHEMBL1301813 Potency 39.8 nM
Oc1nncc(N/N=C/c2ccccn2)n1 CHEMBL1989750 Potency 39.8 nM
O=C(O)c1cccc(-n2cccc2/C=C2/NC(=O)N(c3ccc(Cl)cc3)C2=O)c1 CHEMBL1424694 Potency 39.8 nM
Cc1[nH]c(O)nc1C(=O)CCCCC(=O)O CHEMBL1403262 Potency 39.8 nM
NC(C(=O)O)C(O)c1ccc(O)c(O)c1 CHEMBL1593851 Potency 39.8 nM
Cc1cccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](Cc2ccccc2)C(=O)OCc2ccccc2)c1 CHEMBL1332764 Potency 39.8 nM
C/C(=N\OCc1nc2ccccc2c(=O)n1/N=C/c1cc(C)cc([N+](=O)[O-])c1O)c1ccccc1 CHEMBL3214310 Potency 39.8 nM
CCCCCCNC(=O)N[C@@H](C(=O)NCCC[C@H]1CN2C(=NC[C@@H]2Cc2ccccc2)N1CCc1cccc(OC)c1)C(C)C CHEMBL1479288 Potency 39.8 nM
O=C(Nc1ccc(Cl)c(Cl)c1)c1ccc(Cn2cc(Cl)cn2)cc1 CHEMBL1343740 Potency 39.8 nM
CC1(COc2ccc(C[C@H]3SC(=O)NC3=O)cc2)CCCCC1 CHEMBL1398683 Potency 44.7 nM
FC(F)(F)c1nc2ccccc2nc1N/N=C/c1c(Cl)cccc1Cl CHEMBL3212695 Potency 44.7 nM
O=C(CSc1nc2ccccc2s1)NNC(=S)Nc1ccc(Cl)cc1 CHEMBL1369165 Potency 44.7 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C\C5=C[C@@H]6C[C@H](C5)C6(C)C)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4761724 IC50 45.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(NN=C5C=C(C)[C@H]6C[C@@H]5C6(C)C)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4750455 IC50 46.0 nM
N[C@@H](CCCCNC(=O)CCCC[C@@H]1SC[C@H]2NC(=O)N[C@H]12)C(=O)O CHEMBL1473893 Potency 50.1 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 Potency 50.1 nM
O=[N+]([O-])c1ccc(O)c(/C=N/Nc2ccc(Cl)nn2)c1 CHEMBL1476264 Potency 50.1 nM
O=C1NC(c2cccc([N+](=O)[O-])c2)=CCN1c1ccccc1O CHEMBL258405 Potency 50.1 nM
Nc1nonc1C(=O)N/N=C/c1cc(Br)ccc1O CHEMBL3189342 Potency 50.1 nM
CCOC(=O)C(=CN=C(N)Nc1nc2ccccc2o1)C(=O)OCC CHEMBL1594556 Potency 50.1 nM
N#CC1=C(SCC(=O)Nc2cccc3cccnc23)NC(=O)C(C#N)C12CCCCC2 CHEMBL1410021 Potency 50.1 nM
COc1ccccc1-c1nc(C#N)c(N2CCc3ccccc3C2)o1 CHEMBL1538120 Potency 50.1 nM
O=C1C=CC2=C3c4cc(O)c(O)cc4CC3(O)COC2=C1O CHEMBL1730100 Potency 56.2 nM
COCc1cc(O)c(O)c(O)c1-c1c(COC)cc(O)c(O)c1O CHEMBL59451 Potency 56.2 nM
FC(F)(F)c1ccccc1-n1ccnc1 CHEMBL277525 Potency 56.2 nM
CC1Cc2ccccc2N1C(=S)NC(=O)c1cccc(Br)c1 CHEMBL1543371 Potency 56.2 nM
CCCCCCCCCC(=O)NNC(=O)c1c(O)c2ccccc2n(CC)c1=O CHEMBL1428377 Potency 56.2 nM
Cc1ccc(/C=N\NC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)o1 CHEMBL3192046 Potency 56.2 nM
CCOC(=O)C1=C[C@@]2(CC)CCCN3CCc4c(n1c1ccccc41)[C@H]32 CHEMBL1360725 Potency 56.2 nM
Cc1ccc(NC(=O)CCCCCC2NC(=O)NC2C)cc1 CHEMBL1343539 Potency 56.2 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccc(Br)s1)C4=O CHEMBL4241424 IC50 63.0 nM
CN(C)CCCSC(=N)N CHEMBL12344 Potency 63.1 nM
C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@H]1CC[C@H]2[C@@H](C)CCCC(C)C CHEMBL1475972 Potency 63.1 nM
CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC1CC1 CHEMBL1450385 Potency 63.1 nM
NC1=NN=C(N2N=C(c3ccc(Br)cc3)CC2(O)C(F)(F)F)n2ncnc2C1 CHEMBL1308991 Potency 63.1 nM
O=C(OCC(=O)N1CCCCCC1)c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1 CHEMBL1348008 Potency 63.1 nM
COc1ccc(C(=O)O)c(OC)n1 CHEMBL1388059 Potency 63.1 nM
O=C(CN1CCOCC1)NNc1c2ccccc2nc2ccccc12 CHEMBL1349895 Potency 63.1 nM
O=C(OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(=O)c2c(O)c(O)cc(C3Oc4cc(O)cc(O)c4CC3OC(=O)c3cc(O)c(O)c(O)c3)c2c1)c1cc(O)c(O)c(O)c1 CHEMBL1451483 Potency 63.1 nM
COc1ccc(C)cc1NC(=O)C(OC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)c2ccccc2)c1)c1ccccc1 CHEMBL1492002 Potency 63.1 nM
Cc1ccccc1CC1(CO)CCCN(C(=O)c2ccccc2N(C)C)C1 CHEMBL1528630 Potency 63.1 nM
COc1ccc(-c2ccc(CCC(=O)O)n2NC(=O)c2ccc(C(C)(C)C)cc2)cc1 CHEMBL1471775 Potency 63.1 nM
O=[N+]([O-])c1cc(Cl)cc(/C=N\Nc2ccccn2)c1O CHEMBL3189325 Potency 63.1 nM
COc1ccc(-c2ccc(OC)c([C@H]3[C@@H]4C=CCC[C@@]4(C)C(=O)N3Cc3ccccc3)c2)cc1OC CHEMBL1550600 Potency 63.1 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@]2(C)C1=O)O/C(=C\c1cc(C(C)(C)C)cc(C(C)(C)C)c1O)C4=O CHEMBL4250901 IC50 64.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5ccc(Cl)cc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4440114 IC50 68.0 nM
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 CHEMBL24 Potency 70.8 nM
CCOc1ccc(NC(=O)C(c2ccccn2)N(C(=O)CCl)c2ccc(OCC)cc2)cc1 CHEMBL1532631 Potency 70.8 nM
O=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccccc21 CHEMBL375126 Potency 70.8 nM
O=C(NC(=S)N1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cccc(Br)c1 CHEMBL1506728 Potency 70.8 nM
CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CN1CCN(C)CC1 CHEMBL1587947 Potency 70.8 nM
Cc1[nH]c(O)nc1C(=O)CCCCC(=O)OCC(=O)Nc1ccccn1 CHEMBL1584083 Potency 70.8 nM
Clc1ccccc1CSc1ncn(-c2ccccc2)n1 CHEMBL1380103 Potency 70.8 nM
CCSC1=N/C(=C\c2ccc3c(c2)OCO3)C(=O)S1 CHEMBL1334755 Potency 70.8 nM
Cc1sc2ncnc(N/N=C/c3ccccc3O)c2c1C CHEMBL3189712 Potency 79.4 nM
CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL1391097 Potency 79.4 nM
COc1ccc(C(=O)Nc2cccc(-c3nc4ncccc4o3)c2C)cc1 CHEMBL1548436 Potency 79.4 nM
CCO[C@H]1OC(C(N)=O)=C[C@@H](c2coc3ccccc3c2=O)[C@@H]1CCCO CHEMBL1390481 Potency 79.4 nM
CCCn1c(/C=N/Nc2nc3ccccc3[nH]2)nc2ccccc21 CHEMBL1996126 Potency 79.4 nM
CN(C)c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 CHEMBL1384056 Potency 79.4 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@]2(C)C1=O)O/C(=C\c1ccc(Br)s1)C4=O CHEMBL4242066 IC50 81.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5cccc([N+](=O)[O-])c5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4587610 IC50 86.0 nM
Oc1cccc(O)c1O CHEMBL307145 Potency 86.5 nM
CCCCCCc1nc(-c2c(O)c(C)c(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)[C@@]23C)cs1 CHEMBL4745693 IC50 88.0 nM
C/C(=C\C(=S)Nc1ccccc1)Nc1cccc2ccccc12 CHEMBL3196873 Potency 89.1 nM
COc1cccc(/C=N/NC(=O)c2ccc(=O)n(C)c2)c1O CHEMBL3198485 Potency 89.1 nM
Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc21 CHEMBL280074 Potency 89.1 nM
COc1ccccc1/C=C1/SC(=O)N(CCC(=O)Nc2ccc(S(=O)(=O)Nc3nccs3)cc2)C1=O CHEMBL1458561 Potency 89.1 nM
C=CCc1ccccc1OCC(O)CNC(C)C CHEMBL1256179 Potency 89.1 nM
CCc1cccc(NC(=O)CCCCCC2NC(=O)NC2C)c1 CHEMBL1608529 Potency 89.1 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=O)NCC3(C)CC(NC(=O)NC[C@]4(C)CCC[C@]5(C)c6ccc(C(C)C)cc6CC[C@@H]45)CC(C)(C)C3)CCC[C@]21C CHEMBL4436247 IC50 90.0 nM
O=c1cc(-c2cc3ccccc3oc2=O)c2ccc(OCc3c(Cl)cccc3Cl)cc2o1 CHEMBL4642359 IC50 99.0 nM
COc1cc(C(=O)NC(=S)N(CCc2ccccc2)CCc2ccccc2)cc(OC)c1OC CHEMBL1320542 Potency 100.0 nM
CN(C(=O)Cc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@@H]1N1CCCC1 CHEMBL1513237 Potency 100.0 nM
CCN(CC(=O)NCc1ccc(Cl)cc1)C(=O)CSCC(=O)Nc1ccc(C)cc1 CHEMBL1317441 Potency 100.0 nM
O=c1c2ccccc2nc(N/N=C/c2c(O)ccc3ccccc23)n1O CHEMBL3193098 Potency 100.0 nM
COC(=O)c1ccc(O)c2nc3c(C=O)c(O)cc(O)c3nc12 CHEMBL1505471 Potency 100.0 nM
Cc1cccc(-n2c(S)nnc2CNC(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)c1 CHEMBL1505677 Potency 100.0 nM
COc1ccc(Cc2nnc(N/N=C/c3ccccc3O)nc2O)cc1OC CHEMBL3195091 Potency 100.0 nM
CCn1c(SCc2cccc(OC)c2)nc2ccccc2c1=O CHEMBL1470781 Potency 100.0 nM
CCN1CCN(c2ccc(NC(=O)c3cccc(OCc4ccccc4)c3)cc2)CC1 CHEMBL1373115 Potency 100.0 nM
COc1ccc2nc(N=Nc3ccc(O)c4ccccc34)sc2c1 CHEMBL1486191 Potency 100.0 nM
O=C(O)c1cc(O)c2c(c1)[C@@H]([C@H]1c3cc(C(=O)O)cc(O)c3C(=O)c3c(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cccc31)c1cccc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c1C2=O CHEMBL445268 Potency 100.0 nM
O=C(O)C1Nc2c(O)cccc2C2C=CCC12 CHEMBL1527520 Potency 100.0 nM
COc1cccc(OC)c1C(=O)NC(=S)NNC(=O)[C@H]1C[C@@H]1c1ccccc1 CHEMBL1452392 Potency 100.0 nM
CCCC(=O)c1cc(O)c(O)cc1O CHEMBL1531716 Potency 100.0 nM
Cc1ccncc1C(N)=O CHEMBL1501622 Potency 100.0 nM
Cc1ccc(NC(=O)CCC(=O)N/N=C/c2cccnc2)cc1 CHEMBL3212259 Potency 100.0 nM
O=S(=O)(O)c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccc(S(=O)(=O)O)cc41)-c1ccc(S(=O)(=O)O)cc1-3)c1ccc(S(=O)(=O)O)cc21 CHEMBL1331939 Potency 100.0 nM
O=C(O)c1cc(N(Cc2ccccc2O)Cc2cc(O)ccc2O)ccc1O CHEMBL103552 Potency 100.0 nM
COCc1ccc(CN2CCCC(CO)(Cc3ccccc3)C2)o1 CHEMBL1353953 Potency 100.0 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=O)NC34CC5CC(CC(C5)C3)C4)CCC[C@]21C CHEMBL4435210 IC50 100.0 nM
Cc1ccc(C)n1-c1ccc(Cl)c(C(=O)O)c1 CHEMBL212406 IC50 110.0 nM
Cc1ccc(NC(=O)NC[C@]2(C)CCC[C@]3(C)c4ccc(C(C)C)cc4CC[C@@H]23)cc1NC(=O)NC[C@]1(C)CCC[C@]2(C)c3ccc(C(C)C)cc3CC[C@@H]12 CHEMBL4442276 IC50 110.0 nM
COCCSc1ccccc1C(=O)Nc1cccnc1 CHEMBL1580247 Potency 112.2 nM
Cc1ccc(Nc2ccc3cc(S(=O)(=O)N4CCC(C)CC4)ccc3n2)c(Cl)c1 CHEMBL1363000 Potency 112.2 nM
C/N=c1\scc(-c2ccccc2F)n1/N=C(\C)c1cccnc1 CHEMBL2001211 Potency 112.2 nM
CC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@@H]3[C@H]2CC[C@]2(C)C(=O)CC[C@H]32)C1 CHEMBL1407011 Potency 112.2 nM
c1ccc(-c2cccc(-c3ccccn3)n2)nc1 CHEMBL89445 Potency 112.2 nM
O=C(CN1CCN(Cc2ccccc2)CC1)N/N=C\C=C/c1ccco1 CHEMBL3189977 Potency 112.2 nM
Oc1cccc2ccc(Nc3ccccn3)nc12 CHEMBL530049 Potency 112.2 nM
CNC(=O)COC(=O)c1ccc([N+](=O)[O-])cc1Cl CHEMBL1353027 Potency 112.2 nM
Cc1ccc(NC(=O)CC(C)N2CCCC2)cc1 CHEMBL1350917 Potency 112.2 nM
CN(C)c1ccc(Nc2ncnc3sc4c(c23)CCCC4)cc1 CHEMBL1359760 Potency 112.2 nM
O=[N+]([O-])c1ccc(O)c(/C=N/NC2=NS(=O)(=O)c3ccccc32)c1 CHEMBL1898074 Potency 112.2 nM
Nc1[nH]c(N=Nc2nc(-c3ccc(Cl)cc3)cs2)c2ccccc12 CHEMBL1399928 Potency 112.2 nM
O=C(NN1C(=O)/C(=C/C=C/c2ccco2)SC1=S)c1ccccc1O CHEMBL1320230 Potency 112.2 nM
COC1=C(OC)C(=O)c2ccccc2C1=O CHEMBL402468 Potency 125.9 nM
CC(C)C(=O)Nc1c(-c2ccccc2)c(=O)c2ccccc2n1C CHEMBL1505707 Potency 125.9 nM
CCOC(=O)C1CCN(Cc2ccc(F)cc2F)CC1 CHEMBL1495901 Potency 125.9 nM
O=C(O)c1cc(O)c2c(c1)[C@H]([C@H]1c3cc(C(=O)O)cc(O)c3C(=O)c3c(O[C@@H]4OC(CO)C(O)C(O)C4O)cccc31)c1cccc(O[C@@H]3OC(CO)C(O)C(O)C3O)c1C2=O CHEMBL1314924 Potency 125.9 nM
NC(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL351042 Potency 125.9 nM
COC(=O)c1ccc(C23CC4(C2)[C@H](CN(Cc2cccnc2)[C@@H]4c2ccccc2)C3c2ccc(C(F)(F)F)cc2)cc1 CHEMBL1398536 Potency 125.9 nM
CC1CC(NC(=O)c2c(O)n3ccsc3nc2=O)CC(C)(C)C1 CHEMBL1334100 Potency 125.9 nM
CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1NNc1ncc(-c2ccccc2)cn1 CHEMBL1480203 Potency 125.9 nM
O=[N+]([O-])c1ccc(COc2ccc(-c3[nH]ncc3-c3ccccc3)c(O)c2)cc1 CHEMBL1413963 Potency 125.9 nM
CCN(CC)CCC(c1ccc(N(C)C)cc1)c1c(O)cc(OC)cc1OC CHEMBL1414392 Potency 125.9 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(CC(C)CCCC(C)(C)O)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4797909 IC50 139.0 nM
NCCc1ccc(O)c(O)c1 CHEMBL1557 Potency 141.3 nM
O=C(Oc1c(Cl)cc(Cl)c2cccnc12)c1cccc([N+](=O)[O-])c1 CHEMBL1580272 Potency 141.3 nM
O=[S+]1([O-])Nc2c(ccc3cccnc23)-c2ccccc21 CHEMBL1589921 Potency 141.3 nM
Cc1cc(N/N=C/c2ccccc2[N+](=O)[O-])nc(-n2nc(C)cc2C)n1 CHEMBL3195226 Potency 141.3 nM
Cc1ccc(S(=O)(=O)N/N=C\c2cc([N+](=O)[O-])ccc2Cl)cc1 CHEMBL3196822 Potency 141.3 nM
O=C(OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1-c1c(C2Oc3cc(O)cc(O)c3CC2O)cc(O)c(O)c1O)c1cc(O)c(O)c(O)c1 CHEMBL1325390 Potency 141.3 nM
CCNC(=S)N/N=C(\C)c1ccc(Cl)s1 CHEMBL3189717 Potency 141.3 nM
CN(C)c1ccc(S(=O)(=O)N(C)C)cc1NC(=O)Cc1cccc2ccccc12 CHEMBL1382096 Potency 141.3 nM
CCCCN(C)C(S)=Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 CHEMBL1361026 Potency 141.3 nM
c1ccc(-c2nnc(-c3ccccn3)[nH]2)nc1 CHEMBL260311 Potency 141.3 nM
O=C(O)C(Cc1ccccc1)N1C(=O)/C(=C/C=C/c2ccco2)SC1=S CHEMBL1575767 Potency 141.3 nM
Oc1ccc(/C=N/NC(=S)Nc2cccnc2)c(O)c1 CHEMBL3196606 Potency 141.3 nM
CN1CCC[C@@H]1c1cccnc1 CHEMBL9732 Potency 141.3 nM
O=C1OCC2OC(O)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2-c2c(O)c(O)c3oc(=O)c4c(c(O)c(O)c5oc(=O)c2c3c54)-c2c1cc(O)c(O)c2O CHEMBL416615 Potency 141.3 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccc(Br)cc1)C4=O CHEMBL3356739 IC50 150.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5ccc(F)cc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4475772 IC50 150.0 nM
COc1ccc(/C=N/Nc2nc(-c3c(O)c(C)c(O)c4c3OC3=CC(O)=C(C(C)=O)C(=O)[C@@]34C)cs2)cc1 CHEMBL4446104 IC50 158.0 nM
O=C(N/N=C/c1cc(Br)cc(Br)c1O)c1cccc(N2CCCC2=O)c1 CHEMBL3192648 Potency 158.5 nM
C/C=C\C1=C(CO)[C@H](O)[C@H]2O[C@@H]2[C@@H]1O CHEMBL2373594 Potency 158.5 nM
CC(C)NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL2062275 Potency 158.5 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 Potency 158.5 nM
COc1cc(O)ccc1/C=N/NC(=O)c1ccc([N+](=O)[O-])cc1 CHEMBL3189375 Potency 158.5 nM
Cc1ccc(C)c(-n2c(S)nnc2-c2cccnc2)c1 CHEMBL1448486 Potency 158.5 nM
COc1cccc(/C=N/NC(=O)c2ccc(O)nn2)c1O CHEMBL3210094 Potency 158.5 nM
CC(C)NC[C@@H](O)COc1cccc2ccccc12 CHEMBL1358662 Potency 158.5 nM
O=C(CSc1ccccn1)N/N=C/c1cc([N+](=O)[O-])ccc1O CHEMBL3194704 Potency 158.5 nM
NCc1cc(O)no1 CHEMBL1256363 Potency 158.5 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)NCCCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(=O)C12C CHEMBL4084310 IC50 160.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccc(C)o1)C4=O CHEMBL4243917 IC50 160.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5ccccc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4551119 IC50 172.0 nM
CCN1C(=O)/C(=C/C=C2\C=CN(CC)c3ccccc32)SC1=S CHEMBL1379365 Potency 177.8 nM
O=C1SC(SCc2ccccc2)=N/C1=C\c1ccc(C(=O)O)cc1 CHEMBL1403321 Potency 177.8 nM
Cn1c(=O)c2c(nc(NN/C=C3/C(=O)NC(=S)N(c4ccccc4)C3=O)n2C)n(C)c1=O CHEMBL1425930 Potency 177.8 nM
O=C(NC(=S)NNC(=O)c1cnccn1)c1ccc(Cl)cc1 CHEMBL1469827 Potency 177.8 nM
CCN1C(C)=C(C)S/C1=C1\SC(=S)N(NC(C)=O)C1=O CHEMBL1430854 Potency 177.8 nM
CCc1nnc(NC(=O)c2cccc(C(=O)Nc3nnc(CC)s3)n2)s1 CHEMBL1562926 Potency 177.8 nM
O=C(NCCCN1CCCCCC1)C(c1ccccc1)C1CCCCC1 CHEMBL1378945 Potency 177.8 nM
COc1ccc(OC)c(CCNC(=O)Cn2sc3nc(C)cc(C)c3c2=O)c1 CHEMBL1510394 Potency 177.8 nM
NC(Cc1cc(O)c(O)cc1O)C(=O)O CHEMBL109037 Potency 177.8 nM
CCOc1ccc(OCc2ccc(C(=O)N/N=C(\C)c3ccccn3)cc2)cc1 CHEMBL3192894 Potency 177.8 nM
COC(=O)c1nnc(N[C@@H](Cc2c[nH]c3ccccc23)C(=O)OC)nc1C(=O)OC CHEMBL1436294 Potency 177.8 nM
CC1(C)[C@@H]2CC=C(COc3ccc4c5c(c(=O)oc4c3)CCC5)[C@H]1C2 CHEMBL3909527 CC50 180.0 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)NCCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(=O)C12C CHEMBL4090202 IC50 190.0 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=O)NCCCCCCNC(=O)NC[C@]3(C)CCC[C@]4(C)c5ccc(C(C)C)cc5CC[C@@H]34)CCC[C@]21C CHEMBL4467521 IC50 190.0 nM
COc1cc(/C=N/Nc2nc(-c3c(O)c(C)c(O)c4c3OC3=CC(O)=C(C(C)=O)C(=O)[C@@]34C)cs2)ccc1O CHEMBL4436400 IC50 192.0 nM
CN(C)C1C(=O)C(C(N)=O)C(=O)C2(O)C(=O)C3C(=O)c4c(O)cccc4C(C)(O)C3C(O)C12 CHEMBL1555535 Potency 199.5 nM
SC1=NCN(Cc2ccccc2)CN1 CHEMBL1369459 Potency 199.5 nM
O=c1c(O)c(-c2ccc(O)cc2O)oc2cc(O)cc(O)c12 CHEMBL28626 Potency 199.5 nM
COCCSc1nnc(NC(=O)c2ccc(NC(C)=O)cc2)s1 CHEMBL1439733 Potency 199.5 nM
CN(C)[C@H]1C(O)=C(C(=O)NCN2CCCC2)C(=O)[C@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@](C)(O)[C@H]3C[C@H]12 CHEMBL1441971 Potency 199.5 nM
CC(=O)Nc1ccc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)cc1 CHEMBL1335745 Potency 199.5 nM
Cc1ccc(SC2=C(Sc3ccc(C)cc3)C(=O)c3ccccc3C2=O)cc1 CHEMBL1387028 Potency 199.5 nM
Oc1ccc(COCc2ccccc2)c2cccnc12 CHEMBL1544371 Potency 199.5 nM
COc1cc(NS(=O)(=O)c2ccc(C)cc2)c2ncccc2c1 CHEMBL1445650 Potency 199.5 nM
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O CHEMBL780 Potency 199.5 nM
NNC(=O)c1ccc(COc2ccc3ccccc3c2)o1 CHEMBL1299738 Potency 199.5 nM
Nc1cccc2c1C(=O)N(C(=O)c1cccc(S(=O)(=O)N3CCCC3)c1)C2=O CHEMBL1566657 Potency 199.5 nM
CCCCC/C=N/NC(=O)c1[nH]c2ccc([N+](=O)[O-])cc2c1C CHEMBL3196223 Potency 199.5 nM
Cc1ccc(/N=C/c2c(C)[nH]n(-c3nc4ccccc4[nH]3)c2=O)cc1 CHEMBL3145285 Potency 199.5 nM
CCc1cccc(N(C)C(=N)Nc2cccc3ccccc23)c1 CHEMBL554054 Potency 199.5 nM
CCCCN(CCCC)CC(=O)Nc1cc(C(F)(F)F)cc2c1SSSSS2 CHEMBL3401896 IC50 220.0 nM
Oc1ccc(N=Nc2ccc3c(c2)OCCO3)c2cccnc12 CHEMBL1306283 Potency 223.9 nM
N#C/C(=C\C1=C(N2CCOCC2)/C(=C/c2cccc([N+](=O)[O-])c2)CC1)C(=O)Nc1ccccc1F CHEMBL1455044 Potency 223.9 nM
CN1CC(O)C2=CC(=O)C(=O)C=C21 CHEMBL1314174 Potency 223.9 nM
c1cc2c(cc1C1CCCCC1)c1c3n2CCN=C3CCC1 CHEMBL1451628 Potency 223.9 nM
CN[C@@H](C)[C@H](O)c1ccccc1 CHEMBL1523964 Potency 223.9 nM
CN1C(=O)N(C)C2=NNC=NC2(O)C1=O CHEMBL1555120 Potency 223.9 nM
O=C(OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL311663 Potency 223.9 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@H](Cc1ccc(O)c(O)c1)C(=O)O CHEMBL324842 Potency 223.9 nM
O=C1CSC(=S)N1/N=C/c1ccc(O)c(O)c1O CHEMBL1987928 Potency 223.9 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)c1ccc(O)c(O)c1 CHEMBL56393 Potency 223.9 nM
O=C(N/N=C\c1cccc([N+](=O)[O-])c1O)C1COc2ccccc2O1 CHEMBL3192557 Potency 223.9 nM
CCN(CC)C(=O)CSc1nc(O)c(Cc2ccccc2)c(=O)n1-c1ccc(C)cc1 CHEMBL1313094 Potency 223.9 nM
CCN(CC)C(=O)CN(c1cccc(Br)c1)S(C)(=O)=O CHEMBL1313762 Potency 223.9 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccccc1Br)C4=O CHEMBL4250945 IC50 230.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1cccc(Br)c1)C4=O CHEMBL4249351 IC50 232.0 nM
COc1cc([C@H](Cc2ccccc2)NC(C)=O)oc(=O)c1 CHEMBL1334926 Potency 251.2 nM
CCOC(=O)CCCc1sc(N)nc1-c1[nH]c(O)nc1C CHEMBL1425549 Potency 251.2 nM
COc1ccccc1N1C(=O)[C@@H]2[C@H](C1=O)[C@H](C(=O)c1ccc(OC(C)=O)cc1)N1N=CC=C[C@@H]21 CHEMBL1494393 Potency 251.2 nM
C/C(=N\NC(=S)NCc1ccccc1)c1ccc(Br)cc1 CHEMBL1978908 Potency 251.2 nM
FC(F)(F)c1ccc(-n2cnnc2S)cc1 CHEMBL1467372 Potency 251.2 nM
Oc1cc2c(cc1O)C1c3ccc(O)c(O)c3OCC1(O)C2 CHEMBL1479103 Potency 251.2 nM
CCOc1ccc2nc(Nc3nc4ccc(NC(C)=O)cc4s3)sc2c1 CHEMBL1509111 Potency 251.2 nM
CC1NC(=O)NC1CCCCCC(=O)NCCc1ccccc1 CHEMBL1391385 Potency 251.2 nM
Oc1[nH]c2ccc(Br)cc2c1N=NC(=S)N1CCOCC1 CHEMBL1583292 Potency 251.2 nM
COc1ccc(/C=N/NC(=O)c2nc(-c3ccccc3)n(-c3ccccc3)n2)c(O)c1 CHEMBL3197127 Potency 251.2 nM
NCCc1cc(O)c(O)cc1O CHEMBL451197 Potency 251.2 nM
CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc(S(C)(=O)=O)cc1 CHEMBL488025 Potency 251.2 nM
Cc1ccccc1NC(=O)NC1(C(=O)NCC2CCCO2)CCCCC1 CHEMBL1536704 Potency 251.2 nM
Cc1noc2ncnc(Nc3ccc(F)cc3)c12 CHEMBL1551512 Potency 251.2 nM
CCO[C@H]1OC(C(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)=C[C@@H](c2ccc(Br)cc2)[C@@H]1CCCO CHEMBL1343054 Potency 251.2 nM
O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1423 Potency 251.2 nM
CCC(c1nc2ccccc2c(=O)n1CCCn1ccnc1)N1C(=O)c2ccccc2C1=O CHEMBL1383104 Potency 251.2 nM
CN(C)c1ccc(C(CNS(=O)(=O)c2ccc3ccccc3c2)c2c[nH]c3ccccc23)cc1 CHEMBL1567624 Potency 251.2 nM
C=CCN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3 CHEMBL318111 Potency 251.2 nM
COc1cc(OC)cc(C(=O)NC(=S)NNC(=O)c2cnccn2)c1 CHEMBL1557023 Potency 251.2 nM
CN1C2CC(OC(=O)C(CO)c3ccccc3)C[C@@H]1[C@H]1OC21 CHEMBL1414418 Potency 251.2 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)Nc3ccc(Br)cc3)C(=O)[C@@]12C CHEMBL2207624 IC50 260.0 nM
O=c1cc(-c2cc3ccccc3oc2=O)c2ccc(OCc3cccc4ccccc34)cc2o1 CHEMBL4643271 IC50 270.0 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=O)Nc3ccc(Cl)cc3)CCC[C@]21C CHEMBL4447343 IC50 280.0 nM
O=c1cc(-c2cc3ccccc3oc2=O)c2ccc(OCc3ccccc3Cl)cc2o1 CHEMBL4643649 IC50 280.0 nM
OCc1nc2cc(Cl)ccc2[nH]1 CHEMBL1385033 Potency 281.8 nM
NNC(=O)c1ccc(Cn2cccn2)o1 CHEMBL1463741 Potency 281.8 nM
Cc1ccc(C)c(NC(=O)Cc2nc(CCl)cs2)c1 CHEMBL1385374 Potency 281.8 nM
Oc1ccc2cc(SSc3ccc4cc(O)ccc4c3)ccc2c1 CHEMBL1489064 Potency 281.8 nM
Cc1cc(-c2nn(-c3ccccc3F)cc2CNCCc2c[nH]cn2)c(C)s1 CHEMBL1386287 Potency 281.8 nM
COc1ccc(N/N=C(/N=Nc2nc(C)cc(O)n2)c2ccccc2)cc1 CHEMBL3193510 Potency 281.8 nM
CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3 CHEMBL53 Potency 281.8 nM
CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@H]21 CHEMBL240773 Potency 281.8 nM
O=[As](O)(c1ccccc1)c1ccc(O)cc1 CHEMBL1446804 Potency 281.8 nM
Nc1ccc(N)c(C(=O)O)c1 CHEMBL1547684 Potency 281.8 nM
COc1ccc(/C=N/NC(=O)c2ccc3[nH]cnc3c2)cc1OC CHEMBL3198552 Potency 281.8 nM
COc1cc(-c2ccc(/N=N\c3ccc4c(S(=O)(=O)O)cc(S(=O)(=O)O)c(N)c4c3O)c(OC)c2)ccc1/N=N\c1ccc2c(S(=O)(=O)O)cc(S(=O)(=O)O)c(N)c2c1O CHEMBL1368261 Potency 281.8 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2OC1c1ccc(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL1514905 Potency 281.8 nM
CC1NC(=O)NC1CCCCCC(=O)Nc1ccc(F)c(Cl)c1 CHEMBL1399113 Potency 281.8 nM
O=c1c(-c2cc(O)c(O)c(O)c2)coc2cc(O)c(O)c(O)c12 CHEMBL1438439 Potency 281.8 nM
COc1ccccc1CNC(=O)COC(=O)c1cc(-c2ccco2)nc2ccccc12 CHEMBL1361703 Potency 281.8 nM
Cc1cc(C)cc(OCc2ccc(C(=O)NN)o2)c1 CHEMBL1341135 Potency 281.8 nM
O=c1c(O)cccc2cc(O)c(O)c(O)c12 CHEMBL66953 Potency 281.8 nM
O=C(CCC(=O)Nc1ccc(Br)cc1)N/N=C/c1cc([N+](=O)[O-])ccc1O CHEMBL3199037 Potency 281.8 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)ccc12 CHEMBL170405 Potency 281.8 nM
Brc1ccc(C2Nc3cccc4cccc(c34)N2)o1 CHEMBL1341830 Potency 316.2 nM
Cc1ccc(NC2=NC(=O)/C(=C/c3cccn3C)S2)c(C)c1 CHEMBL1450772 Potency 316.2 nM
Cc1ccc(OCC(=O)N/N=C/c2cccn2C)cc1C CHEMBL3198232 Potency 316.2 nM
COc1ccc(CN2CCc3cc(OC)c(OC)cc3C2)cc1O CHEMBL1414604 Potency 316.2 nM
COc1ccc(C2=NN(c3ccc(C=O)cc3)C(c3ccccc3)C2)cc1 CHEMBL1502271 Potency 316.2 nM
O=C1c2ccccc2C(=O)c2c(O)c(O)cc(O)c21 CHEMBL294264 Potency 316.2 nM
Cc1cc(NC(=O)CSC2=NCCS2)no1 CHEMBL1442935 Potency 316.2 nM
Oc1cc2c(cc1O)[C@H]1c3ccc(O)c(O)c3OC[C@@]1(O)C2 CHEMBL1448387 Potency 316.2 nM
Cc1c2c(c(O)c3c(O)cccc13)C(=O)O[C@H]2C1C(N(C)C)C(O)=C(C(N)=O)C(=O)[C@H]1O CHEMBL1443157 Potency 316.2 nM
NCCc1cc(O)c(O)cc1O CHEMBL337702 Potency 316.2 nM
CC1=NN(c2nc(-c3ccc(C)cc3)cs2)C(=O)C1N=Nc1ccccc1O CHEMBL1482998 Potency 316.2 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL297453 Potency 316.2 nM
CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)c1[nH]cnc1C(=O)Nc1ccc(CNC(=O)OC(C)(C)C)cc1)C(=O)OC(C)(C)C CHEMBL1428437 Potency 316.2 nM
Cc1c(NC(=S)N/N=C/c2cc([N+](=O)[O-])ccc2O)c(=O)n(-c2ccccc2)n1C CHEMBL3212364 Potency 316.2 nM
CCCCNc1nc2sc3c(c2c(=O)n1-c1cccc(Cl)c1)CCN(C)C3 CHEMBL1351451 Potency 316.2 nM
OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)nc(N3CCCCC3)c2n1 CHEMBL932 Potency 316.2 nM
N=C(NOC(=O)c1cnn(-c2ccccc2)c1C(F)(F)F)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL1600366 Potency 316.2 nM
COc1cc(/C=N/Nc2ccccn2)ccc1OCC(C)C CHEMBL1988339 Potency 316.2 nM
O=c1oc2c(cc1O)oc(=O)c1cc(O)c(O)c(O)c12 CHEMBL1601846 Potency 316.2 nM
Nc1cc(N)nc(SCc2cc([N+](=O)[O-])cc3c2OCOC3)n1 CHEMBL1338286 Potency 316.2 nM
N=C1Sc2ccccc2C2=NCCCN12 CHEMBL595227 Potency 316.2 nM
COc1ccccc1/C=C1\SC(NNC(=O)c2cccc(Br)c2)=NC1=O CHEMBL1438084 Potency 316.2 nM
CC1CC(C)(C)OC(C[N+]2(C)CCCCC2)O1 CHEMBL1450918 Potency 316.2 nM
NCCNCCNCCNCCN CHEMBL138297 Potency 316.2 nM
O=C(O)C1C(C(=O)O)C2(Cl)C(Cl)=C(Cl)C1(Cl)C2(Cl)Cl CHEMBL462314 Potency 316.2 nM
O=C(OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1-c1c(C2Oc3cc(O)cc(O)c3CC2OC(=O)c2cc(O)c(O)c(O)c2)cc(O)c(O)c1O)c1cc(O)c(O)c(O)c1 CHEMBL1394337 Potency 316.2 nM
CCN(CC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl)Cc1ccccc1 CHEMBL1408749 Potency 316.2 nM
Cc1cc(=O)oc2cc(OCC3=CC[C@@H]4C[C@H]3C4(C)C)ccc12 CHEMBL3904764 CC50 320.0 nM
CC1(C)[C@H]2CC=C(COc3ccc4c5c(c(=O)oc4c3)CCC5)[C@@H]1C2 CHEMBL3928452 CC50 330.0 nM
Cc1cc(=O)oc2cc(OCC3=CC[C@H]4C[C@@H]3C4(C)C)ccc12 CHEMBL3966564 CC50 340.0 nM
COc1ccc(/C=C2\Oc3c(C)c(O)c4c(c3C2=O)OC2=CC(O)=C(C(C)=O)C(=O)[C@@]24C)cc1 CHEMBL4242317 IC50 340.0 nM
COc1ccc(/C=C2\Oc3c(C)c(O)c4c(c3C2=O)OC2=CC(O)=C(C(C)=O)C(=O)[C@@]24C)c(OC)c1OC CHEMBL4251391 IC50 340.0 nM
O=C(O)CCCCC1CCSS1 CHEMBL33864 Potency 344.4 nM
CC(C)n1c(=S)[nH]c2scc(-c3cccs3)c2c1=O CHEMBL1329286 Potency 354.8 nM
O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(Cl)s1 CHEMBL1304363 Potency 354.8 nM
CC/C(NCc1cccnc1)=C1/C(=O)NC(=O)N(c2ccccc2C)C1=O CHEMBL1481117 Potency 354.8 nM
COc1ccc(-c2c(NC(=O)c3ccco3)n(-c3ccccc3)nc(C)c2=O)cc1 CHEMBL1345357 Potency 354.8 nM
O=C(/C=C/c1ccccc1)c1c[nH]c2ccccc12 CHEMBL1598418 Potency 354.8 nM
O=C(O)C1Nc2ccccc2C2C=CCC12 CHEMBL492894 Potency 354.8 nM
O=C1C=CC(=O)c2c(O)cccc21 CHEMBL43612 Potency 354.8 nM
O=C(CCc1ccccc1)NCc1ccccn1 CHEMBL1364346 Potency 354.8 nM
Cc1cccc(Cn2ccc(N)n2)c1 CHEMBL1507165 Potency 354.8 nM
C[C@H](N)[C@H](O)c1ccc(O)c(O)c1 CHEMBL677 Potency 354.8 nM
CC(C)N1C(=O)/C(=C\c2nc(O)c3ccccc3n2)c2ccccc21 CHEMBL1308170 Potency 354.8 nM
C=C1c2c(Cl)ccc(O)c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)C(N(C)C)C3C(O)C12 CHEMBL1592095 Potency 354.8 nM
O=c1c(O)cc(C2Oc3cc(O)cc(O)c3CC2O)cc2c(C3Oc4cc(O)cc(O)c4CC3O)cc(O)c(O)c12 CHEMBL1512440 Potency 354.8 nM
COc1ccc(/C=C2\C(=O)NC(=S)N(C)C2=O)cc1C CHEMBL1477703 Potency 354.8 nM
O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12 CHEMBL8145 Potency 354.8 nM
Cc1ccc2c(c1)Sc1c(ccc3ccccc13)N2 CHEMBL1300506 Potency 354.8 nM
c1ccc2nc(N3CCNCC3)ccc2c1 CHEMBL18772 Potency 354.8 nM
CCCCC(=O)NN/C=C1\C(=O)NC(=O)N(CCc2ccc(OC)c(OC)c2)C1=O CHEMBL1399542 Potency 354.8 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCCCNC(=O)/C(C#N)=C/c1ccc(O)c(O)c1 CHEMBL67535 Potency 354.8 nM
Cc1ccc(C(CCNC(C)c2cccs2)c2ccco2)cc1 CHEMBL1517631 Potency 354.8 nM
CN(N=O)c1ccc(O)c(O)c1 CHEMBL1256623 IC50 360.0 nM
COc1cccc2cc(-c3cc(=O)oc4c(C)c(OCc5ccc(Cl)cc5)ccc34)c(=O)oc12 CHEMBL4648584 IC50 360.0 nM
COc1ccccc1/C=C1\Oc2c(C)c(O)c3c(c2C1=O)OC1=CC(O)=C(C(C)=O)C(=O)[C@@]13C CHEMBL3356738 IC50 390.0 nM
CCN(CC)C(=O)N[C@@H]1C[C@H]2c3cccc4[nH]cc(c34)C[C@@H]2N(C)C1 CHEMBL1433815 Potency 398.1 nM
Cc1ccc(OCC(=O)N2CCN(C3CCC(c4ccccc4)CC3)CC2)cc1 CHEMBL1536328 Potency 398.1 nM
O=C1N=C(NNC(=O)c2cccc3ccccc23)S/C1=C\c1ccccc1OCc1ccccc1 CHEMBL1575272 Potency 398.1 nM
COC(=O)c1cccnc1Oc1ccccc1 CHEMBL1301950 Potency 398.1 nM
CCOC(=O)NC1(NCC(C)C)Oc2ccccc2O1 CHEMBL1384398 Potency 398.1 nM
NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 CHEMBL41631 Potency 398.1 nM
COC(=O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@]21O CHEMBL1454198 Potency 398.1 nM
CC(C)c1ccc(N2C(=O)CC(Sc3nc[nH]n3)C2=O)cc1 CHEMBL1503380 Potency 398.1 nM
C=CCn1c(=S)[nH]c2scc(-c3ccc(C)o3)c2c1=O CHEMBL1376201 Potency 398.1 nM
O=[N+]([O-])c1ccc(O)c2ncccc12 CHEMBL1454910 Potency 398.1 nM
O=C(NCCCn1ccnc1)c1nc(Cn2cc([N+](=O)[O-])cn2)no1 CHEMBL1346289 Potency 398.1 nM
CN(C)c1ccc(C2CC(c3cccc(NS(C)(=O)=O)c3)=NN2C(=O)c2ccccc2)cc1 CHEMBL1482228 Potency 398.1 nM
Cc1ccc(NN2C(=O)C=C(c3ccc(Cl)cc3)C2=O)cc1 CHEMBL1560954 Potency 398.1 nM
Oc1cccc(C(Nc2nccs2)c2ccc3cccnc3c2O)c1 CHEMBL1426340 Potency 398.1 nM
COC1=CC(=O)CC(C)C12Oc1c(Cl)c(OC)cc(OC)c1C2=O CHEMBL1369825 Potency 398.1 nM
Cc1cc(C)cc(N2C(=O)CC(Sc3nc[nH]n3)C2=O)c1 CHEMBL1608472 Potency 398.1 nM
CCCC(=O)NC(c1cccs1)c1cc(Cl)c2cccnc2c1O CHEMBL530499 Potency 398.1 nM
CC(=O)C(=NNc1ccc(-n2ccc(C(F)(F)F)n2)cc1)C(C)=O CHEMBL1311928 Potency 398.1 nM
CC(=O)Nc1ccc(NC(=O)Cc2ccc(S(=O)(=O)N3CCCCC3)cc2)cc1 CHEMBL1573830 Potency 398.1 nM
O=C(NNC(=S)NC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1)c1ccncc1 CHEMBL1418389 Potency 398.1 nM
CCN=C(S)NNC(=O)c1cc(-c2cc(C)ccc2C)nc2ccccc12 CHEMBL1431710 Potency 398.1 nM
NC[C@@H](O)c1ccc(O)c(O)c1 CHEMBL18824 Potency 398.1 nM
COc1ccc(/C=C/C(=O)NC(=S)NNC(=O)c2ccco2)cc1 CHEMBL1471170 Potency 398.1 nM
CCOC(=O)c1cc(OC(=O)c2ccccc2OC)n(-c2ccccc2)n1 CHEMBL1536053 Potency 398.1 nM
CN(C)c1ccc(NC(=O)Nc2csc3ccccc23)cc1 CHEMBL1584271 Potency 398.1 nM
O=c1c2ccccc2sn1-c1ccccc1 CHEMBL45152 Potency 398.1 nM
CC(=O)c1c(CC(=O)O)[nH]n(-c2nc3ccccc3s2)c1=O CHEMBL3145073 Potency 398.1 nM
CC(=O)Oc1cc(-c2coc3cc(OC(C)=O)c(OC(C)=O)c(OC(C)=O)c3c2=O)cc(OC(C)=O)c1OC(C)=O CHEMBL1440119 Potency 398.1 nM
Cc1ccc(/C=N/Nc2cc(C)nc(NCc3ccccc3)n2)cc1 CHEMBL3193493 Potency 398.1 nM
CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3[C@H](O)[C@@H]12 CHEMBL1517 Potency 398.1 nM
COc1ccc2cc(C(=O)N/N=C/c3sc4ccccc4c3O)ccc2c1 CHEMBL1982539 Potency 398.1 nM
O=C1NC(=O)N(Cc2ccco2)C(=O)/C1=C/C=C/c1ccco1 CHEMBL1597042 Potency 398.1 nM
Cc1cccc(NC(=O)c2nc[nH]c2C(=O)N[C@@H](C)C(=O)OC(C)(C)C)c1 CHEMBL1486702 Potency 398.1 nM
CC1(C)[C@@H]2CC=C(COc3ccc4c5c(c(=O)oc4c3)CCCC5)[C@H]1C2 CHEMBL3918464 CC50 410.0 nM
CC(C)[C@H](NC(=O)c1ccccc1Cl)C(=O)Nc1nc(-c2ccccn2)cs1 CHEMBL1606890 Potency 446.7 nM
CCC(C)c1ccccc1NC(=O)COc1ccc(-c2nnco2)cc1 CHEMBL1598074 Potency 446.7 nM
O=C(c1ccccc1F)N1CCN(Cc2cccc(Cl)c2)CC1 CHEMBL1580452 Potency 446.7 nM
Cc1ccc(N=C(S)c2nc3ccccc3[nH]2)c(C)c1 CHEMBL1375468 Potency 446.7 nM
COc1cc(OC)cc(-c2nnc(Nc3nc4c(F)cccc4s3)o2)c1 CHEMBL473314 Potency 446.7 nM
CN1C[C@@H](C(=O)N[C@@]2(C)O[C@]3(O)[C@H]4CCCN4C(=O)[C@@H](Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)C[C@@H]21 CHEMBL1402957 Potency 446.7 nM
Cc1ccc(NCC(=O)N=Nc2c(O)n(C)c3ccccc23)cc1 CHEMBL1375961 Potency 446.7 nM
Cc1ccnc(NC(c2cccnc2)c2ccc3cccnc3c2O)c1 CHEMBL1323744 Potency 446.7 nM
Cc1ccc(NC(S)=NNC(=O)C2CC2c2ccc(C)cc2)cc1 CHEMBL1385999 Potency 446.7 nM
Cc1ccc(C)c(-c2cc(C(=O)NNC(S)=NCC(C)C)c3ccccc3n2)c1 CHEMBL1581920 Potency 446.7 nM
NCCc1ccc(O)c(O)c1 CHEMBL59 Potency 446.7 nM
CCc1ccccc1NNC(=O)c1snnc1C CHEMBL1504297 Potency 446.7 nM
Cc1onc(-c2ccccc2)c1C(=O)NNC(=S)NC(=O)c1ccc2c(c1)OCO2 CHEMBL1416153 Potency 446.7 nM
C=C1c2cccc(O)c2C(=O)C2=C(O)[C@@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12 CHEMBL1560884 Potency 446.7 nM
CCCC(=O)NC(c1ccc(OC)c(OC)c1)c1cc(Cl)c2cccnc2c1O CHEMBL239275 Potency 446.7 nM
CC1CCCCC12NC(=O)N(CC(=O)Nc1sc3c(c1C(N)=O)CCC3)C2=O CHEMBL1443726 Potency 446.7 nM
Nc1cc(N)nc(CS)n1 CHEMBL1467712 Potency 446.7 nM
Oc1c(Cl)cc(Cl)c2cccnc12 CHEMBL1200596 Potency 446.7 nM
OCc1ccccc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O CHEMBL462997 Potency 446.7 nM
Fc1ccc(C(CCNCc2cccs2)c2ccco2)cc1 CHEMBL1392163 Potency 446.7 nM
CCCn1c(Nc2nc3ccccc3n2C)nc2ccccc21 CHEMBL393287 Potency 446.7 nM
N=C(N)SCCN CHEMBL1256182 Potency 446.7 nM
CCCCOc1ccc(-c2cc(C(=O)NN=C(S)NCC)c3ccccc3n2)cc1 CHEMBL1310341 Potency 446.7 nM
CC(C)(C)c1cc(N/C=C\c2nnnn2-c2ccc(Br)cc2)no1 CHEMBL1468852 Potency 446.7 nM
N#CC(C#N)=C(N)/C(C#N)=C/c1cc(O)c(O)c(O)c1 CHEMBL78257 Potency 446.7 nM
Cc1ccc(-n2[nH]c(C)c(/C=N/Nc3ccc([N+](=O)[O-])cc3[N+](=O)[O-])c2=O)cc1 CHEMBL3145244 Potency 446.7 nM
Cc1cccc(C)c1NC(=O)CCCCCC1NC(=O)NC1C CHEMBL1369512 Potency 446.7 nM
CCC1=C(OC(=O)N(CC)CC)N2C(=O)O/C(=N\CC3CC3)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(c3ccccc3)C(=O)[C@H]12 CHEMBL3190029 Potency 446.7 nM
C/C(=N\NC1=NC(=O)C(CC(=O)O)S1)c1ccccn1 CHEMBL3192868 Potency 446.7 nM
CCCOc1ccc(C(=O)NNC(=S)NC(=O)c2cc(-c3ccc(Cl)cc3)nc3ccccc23)cc1 CHEMBL1361054 Potency 446.7 nM
Cn1cccc1/C=C1\SC(=S)N(NC(=O)c2ccc(Cl)cc2)C1=O CHEMBL1608144 Potency 446.7 nM
COc1ccccc1N(CC(=O)NCc1ccc(F)cc1)C(=O)CCC(=O)Nc1nccs1 CHEMBL1420147 Potency 446.7 nM
C[C@]12CC[C@@H]3c4cc(O)c(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O CHEMBL467987 Potency 446.7 nM
CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])cc2)cc1 CHEMBL493636 Potency 446.7 nM
Oc1c(Br)cc(/C=N/n2c(S)nnc2-c2ccccc2)c(Br)c1O CHEMBL3191015 Potency 446.7 nM
CN(C)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3ccc4c(c3)CCCC4)o2)cc1 CHEMBL1452449 Potency 446.7 nM
CCOC(=O)C(=O)Nc1cc(C)nn1-c1nc2ccccc2[nH]1 CHEMBL1374319 Potency 446.7 nM
Nc1ccccc1[As](=O)(O)c1ccccc1 CHEMBL1383606 Potency 446.7 nM
Nc1cccc([As](=O)(O)c2ccccc2)c1 CHEMBL1511311 Potency 446.7 nM
O=C1C(=O)C(c2cc(O)c(O)c(O)c2)Oc2cc(O)cc(O)c21 CHEMBL198468 Potency 446.7 nM
Cc1nn2c(N3CCN(CCO)CC3)c3c(nc2c1-c1ccccc1)CCCC3 CHEMBL1487086 Potency 446.7 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1cccnc1)C4=O CHEMBL3356741 IC50 450.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(N/N=C/c5ccc(O)cc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4533174 IC50 457.0 nM
COc1cc(/C=C2\SC(=S)N(N(C)c3ccccc3)C2=O)ccc1O CHEMBL1495138 Potency 474.0 nM
Nc1c(C(=O)Nc2cccc(C(F)(F)F)c2)sc2nc3c(cc12)CCCCCC3 CHEMBL3771079 IC50 500.0 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=O)NC3CCCCC3)CCC[C@]21C CHEMBL4460313 IC50 500.0 nM
Cc1ccc(C(=O)NCC(=O)N2CCN(c3ccccc3)CC2)cc1 CHEMBL1379207 Potency 501.2 nM
C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL459 Potency 501.2 nM
C=CCNC(=S)N/N=C(\C)c1ccccn1 CHEMBL455284 Potency 501.2 nM
O=C1NC(=S)N(Cc2ccco2)C(=O)/C1=C\c1cccs1 CHEMBL1541005 Potency 501.2 nM
CCN(CC)c1ccc(/C=N/Nc2nc(C)cc(O)n2)c(O)c1 CHEMBL3197978 Potency 501.2 nM
NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1437 Potency 501.2 nM
Cc1nc(/N=N\c2cc(S(=O)(=O)[O-])c3cc([N+](=O)[O-])cc(S(=O)(=O)[O-])c3c2)c(COP(=O)([O-])[O-])c(C=O)c1O CHEMBL1490919 Potency 501.2 nM
C[C@@H](N)[C@@H](O)c1ccc(O)c(O)c1 CHEMBL1160982 Potency 501.2 nM
CCOc1cccc(C(=O)C2=C(O)C(=O)N(CCOC)C2c2ccco2)c1 CHEMBL1455212 Potency 501.2 nM
CCCCN(CC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3cccs3)o2)cc1 CHEMBL1306666 Potency 501.2 nM
Oc1ccc(-c2cn3c(n2)SCC3)cc1O CHEMBL1613004 Potency 501.2 nM
C=CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)c4cccs4)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13 CHEMBL1323984 Potency 501.2 nM
CCCCOc1cccc(-c2cc(C(=O)NN=C(S)NCC)c3ccccc3n2)c1 CHEMBL1307776 Potency 501.2 nM
CC(CNc1ccc([N+](=O)[O-])c2cccnc12)Nc1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL1483311 Potency 501.2 nM
CN(N=O)c1cc(O)ccc1O CHEMBL269733 Potency 501.2 nM
COc1ccc(-c2nnc(Nc3nc4c(OC)cccc4s3)o2)c(OC)c1 CHEMBL1612493 Potency 501.2 nM
CC1CC(C)CN(S(=O)(=O)c2ccc(C(=O)Nc3nnc(-c4cccs4)o3)cc2)C1 CHEMBL1445590 Potency 501.2 nM
CCOC(=O)NC1(NC2CCCCC2)Oc2ccccc2O1 CHEMBL1366858 Potency 501.2 nM
O=C(O)c1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O CHEMBL418068 Potency 501.2 nM
NNC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1390521 Potency 501.2 nM
O=C(Nc1cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])c1)Nc1cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])cc(C(=O)Nc2ccc(S(=O)(=O)[O-])cc2S(=O)(=O)[O-])c1 CHEMBL1253351 Potency 501.2 nM
CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3[C@H](O)[C@@H]12 CHEMBL1607480 Potency 501.2 nM
N#C/C(=C/c1ccc(O)c(O)c1)C(=O)OC/C=C/c1ccccc1 CHEMBL1553859 Potency 501.2 nM
CC[C@H](c1ccc(O)cc1)[C@@H](CC)c1ccc(O)cc1 CHEMBL9225 Potency 501.2 nM
O=C(Nc1nc(-c2ccccn2)cs1)c1ncc(Cl)c(Cl)c1Cl CHEMBL1319984 Potency 501.2 nM
O=C(/C=C/c1ccco1)NC(=S)NNC(=O)c1ccco1 CHEMBL1440636 Potency 501.2 nM
Cn1c(S)nnc1-c1sccc1OCc1ccc(Cl)cc1Cl CHEMBL1576713 Potency 501.2 nM
N[C@@H](Cc1ccc(O)c(O)c1)C(=O)O CHEMBL1009 Potency 501.2 nM
COC(=O)c1cccc(C23CC4(C2)[C@H](CN(Cc2cccnc2)[C@@H]4c2ccccc2)C3c2ccccc2)c1 CHEMBL1491435 Potency 501.2 nM
Cc1c(NC(=O)c2cccnc2)c(=O)n(-c2ccccc2)n1C CHEMBL1413176 Potency 501.2 nM
CCCSC1=N/C(=C\c2ccc3c(c2)OCO3)C(=O)S1 CHEMBL1577386 Potency 501.2 nM
C=CCn1c(O)nnc1Sc1ncc([N+](=O)[O-])s1 CHEMBL1423626 Potency 501.2 nM
O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I CHEMBL1332616 Potency 501.2 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1cc(Br)cc(Br)c1)C4=O CHEMBL4240521 IC50 530.0 nM
CN(C)c1ccc(CN(C(=O)C2COc3ccccc3O2)C2CCS(=O)(=O)C2)cc1 CHEMBL1457888 Potency 562.3 nM
COc1cc(-c2nnc(SCc3cc(=O)oc4cc(O)c(O)cc34)o2)cc(OC)c1OC CHEMBL1381627 Potency 562.3 nM
N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCCCCc1ccccc1 CHEMBL440298 Potency 562.3 nM
O=C1/C(=C/c2ccco2)SC(=S)N1c1cccnc1 CHEMBL1609550 Potency 562.3 nM
O=C(N/N=C/c1cc([N+](=O)[O-])ccc1O)c1cccc2cc[nH]c12 CHEMBL1988121 Potency 562.3 nM
CC(=O)N[C@@H]1C(O)OC(CO)C(O)C1O CHEMBL1414815 Potency 562.3 nM
COc1ccc2c(CC(=O)OCC(=O)Nc3cccc(S(N)(=O)=O)c3)coc2c1 CHEMBL1580348 Potency 562.3 nM
COCC/N=c1\scc(-c2cc(OC)ccc2OC)n1/N=C/c1c[nH]c2ccccc12 CHEMBL3199359 Potency 562.3 nM
CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3cc(OC)cc(OC)c3)o2)cc1 CHEMBL1609946 Potency 562.3 nM
CCn1c(S)nnc1-c1ccc(Cl)cc1 CHEMBL1371049 Potency 562.3 nM
Cc1cccc(N2C(=O)/C(=C\NNc3nc4c(c(=O)n(C)c(=O)n4C)n3C)C(=O)NC2=S)c1 CHEMBL1533497 Potency 562.3 nM
COc1ccc2cc(/C(C)=N/NC(=S)Nc3cc(S(=O)(=O)N4CCOCC4)ccc3N3CCOCC3)ccc2c1 CHEMBL3199850 Potency 562.3 nM
N[C@H](Cc1ccc(O)c(O)c1)C(=O)O CHEMBL211670 Potency 562.3 nM
Cc1cc2nc(CCl)cc(O)n2n1 CHEMBL1351111 Potency 562.3 nM
CCOC(=O)c1ccc(NC(=S)N2CCSC2c2c(F)cc(F)cc2F)cc1 CHEMBL1391066 Potency 562.3 nM
CC(=O)Oc1cc2cccc(OC(C)=O)c(=O)c2c(OC(C)=O)c1OC(C)=O CHEMBL1485442 Potency 562.3 nM
CCN(CC)c1ccc(C=C2C(=O)NC(=S)NC2=O)cc1 CHEMBL1600146 Potency 562.3 nM
COc1ccccc1-c1nnc(Nc2nc3c(OC)cccc3s2)o1 CHEMBL1544633 Potency 562.3 nM
C=CC1=C(C)C2=N/C1=C\C1=[N+]3[Zn-2][N+]4=C(/C=C5\N=C(/C=C\3C(CCC(=O)O)=C1C)C(CCC(=O)O)=C5C)C(C)=C(C=C)/C4=C/2 CHEMBL1476362 Potency 562.3 nM
COc1c(O)cc2c(=O)oc3c(OC)c(O)cc4c(=O)oc1c2c34 CHEMBL487203 Potency 562.3 nM
CCCOc1ccc(C(=O)NNC(=S)NC(=O)c2cc(-c3ccccc3)nc3ccccc23)cc1 CHEMBL1485818 Potency 562.3 nM
Cc1ccc(OCC(=O)NN2C(=O)c3ccccc3C2=O)c(C)c1 CHEMBL1311946 Potency 562.3 nM
CC(C)Cn1c(S)nnc1-c1ccccc1F CHEMBL1561952 Potency 562.3 nM
CCN1CCc2c(sc(NC(=S)NC(=O)c3ccc(Cl)cc3)c2C(N)=O)C1 CHEMBL1613508 Potency 562.3 nM
CC(=O)NC(c1cccs1)c1cc([N+](=O)[O-])c2cccnc2c1O CHEMBL1348582 Potency 562.3 nM
Cc1cc(/C=N/NC(=O)C(=O)NCc2ccccn2)c(C)n1-c1cccc(Br)c1 CHEMBL3209700 Potency 562.3 nM
Nc1c(C(=O)NCC2CCCO2)sc2nc3c(c(-c4ccco4)c12)CC/C3=C\c1ccco1 CHEMBL1594376 Potency 562.3 nM
COc1ccc(/C=C/C(=O)NC(=S)NNC(=O)Cc2cccs2)cc1OC CHEMBL1419057 Potency 562.3 nM
C(=N/Nc1nc2ccccc2[nH]1)\c1c[nH]c2ccccc12 CHEMBL2002487 Potency 562.3 nM
CC1=C(C#N)C(=O)N(C2CCS(=O)(=O)C2)C(=O)/C1=C\c1ccco1 CHEMBL1497651 Potency 562.3 nM
O=C1C2C3C=CC(CO)(O3)C2C(=O)N1c1ccc(-c2ccccc2)cc1 CHEMBL1399096 Potency 562.3 nM
CCC(=O)N=c1nc(S)ss1 CHEMBL1400958 Potency 562.3 nM
COc1ccc2nc(N3C(=O)C(c4c(O)[nH]c5ccccc45)=NC3=S)sc2c1 CHEMBL1539579 Potency 562.3 nM
CCCCC1CCCC12NC(=O)NC2=O CHEMBL1605803 Potency 562.3 nM
COc1cccc(-c2oc3ccccc3c(=O)c2O)c1 CHEMBL272005 Potency 562.3 nM
Oc1ccc(O)c2c(O)cccc12 CHEMBL1331245 Potency 562.3 nM
O=C(NN1C(=O)/C(=C/c2cc([N+](=O)[O-])ccc2O)SC1=S)c1ccccc1O CHEMBL1512549 Potency 562.3 nM
COc1cc(Nc2nc3ccccc3c3nnc(C)n23)cc(OC)c1 CHEMBL1551991 Potency 562.3 nM
COc1cccc2c1NC(C(=O)O)C1CC=CC21 CHEMBL1528814 Potency 562.3 nM
Cn1c(Cl)cnc1/C=C/C(=O)c1cc(Cl)ccc1O CHEMBL1341399 Potency 562.3 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)Nc3ccc(Br)cc3)C(=O)[C@]12C CHEMBL2207625 IC50 570.0 nM
C=CCNC(=S)NC[C@]1(C)CCC[C@]2(C)c3ccc(C(C)C)cc3CC[C@@H]12 CHEMBL4577295 IC50 570.0 nM
c1ccc(-c2cc(-c3ccc(N4CCOCC4)cc3)nc3ccccc23)cc1 CHEMBL1438476 Potency 596.7 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1cc(Br)cs1)C4=O CHEMBL4240984 IC50 600.0 nM
CC(=O)C1=C(O)C=C2Oc3c(-c4csc(Nc5ccccc5)n4)c(O)c(C)c(O)c3[C@@]2(C)C1=O CHEMBL4455616 IC50 610.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1sccc1C)C4=O CHEMBL4237246 IC50 630.0 nM
COc1ccc2c(/C=N/NS(=O)(=O)c3ccc(C)cc3)c[nH]c2c1 CHEMBL3189503 Potency 631.0 nM
COC(=O)c1ccccc1NC1=C/C(=N\S(=O)(=O)c2cccs2)c2ccccc2C1=O CHEMBL3195749 Potency 631.0 nM
c1coc(-c2nc(-c3ccco3)c(-c3ccco3)nc2-c2ccco2)c1 CHEMBL1384172 Potency 631.0 nM
CCCCN(CC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3ccccc3Cl)o2)cc1 CHEMBL1384368 Potency 631.0 nM
COc1ccc(O)c(N)c1 CHEMBL1502381 Potency 631.0 nM
C/C(=N\Nc1ccccc1[N+](=O)[O-])c1ccccc1O CHEMBL3196921 Potency 631.0 nM
CC(=O)N1CCN(S(=O)(=O)c2cccc(C(=O)Nc3ccccc3N3CCCCC3)c2)CC1 CHEMBL1513255 Potency 631.0 nM
CC(N)[C@H](O)c1ccc(O)c(O)c1 CHEMBL1320902 Potency 631.0 nM
CC(N)(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL718 Potency 631.0 nM
CN(C)C1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@](C)(O)C3C(O)C12 CHEMBL1475999 Potency 631.0 nM
Cc1cc(NC(=O)/C=C/c2ccc(F)cc2)n(-c2nc3ccccc3[nH]2)n1 CHEMBL1543354 Potency 631.0 nM
O=C(O)c1ccc(N/N=C/C2=C(N3CCOCC3)/C(=C\c3ccccc3)CC2)cc1 CHEMBL1972621 Potency 631.0 nM
O=C(/C=C/c1cccs1)NC(=S)NNC(=O)Cc1cccs1 CHEMBL1528965 Potency 631.0 nM
Cc1[nH]c2ccccc2c1SCC(=O)NNC(=O)Nc1ccc(OC(F)(F)F)cc1 CHEMBL1600149 Potency 631.0 nM
O=C(O)C1Nc2ccc(Br)cc2C2C=CCC12 CHEMBL201289 Potency 631.0 nM
Cc1ccnc(-n2sc3ccccc3c2=O)n1 CHEMBL608699 Potency 631.0 nM
COC(=O)Cc1cc(O)n2nc(C)c(-c3ccccc3)c2n1 CHEMBL1496237 Potency 631.0 nM
NCCS CHEMBL1256137 Potency 631.0 nM
COc1cccc2sc(Nc3nnc(-c4ccc(F)cc4)o3)nc12 CHEMBL1390963 Potency 631.0 nM
N[C@@]1(C(=O)O)CC[C@H](C(=O)O)C1 CHEMBL29726 Potency 631.0 nM
O=C1NC(=S)S/C1=C\c1ccc(SCc2ccco2)o1 CHEMBL1405834 Potency 631.0 nM
COC(=O)CCCCC1SCC2NC(=O)NC21O CHEMBL1391310 Potency 631.0 nM
Oc1c(Br)cc(Br)c2cccnc12 CHEMBL223448 Potency 631.0 nM
Cc1ccccc1-n1nc(C(=O)c2cccs2)cc(-c2nc3ccccc3[nH]2)c1=N CHEMBL1505760 Potency 631.0 nM
CCCCCC#CCC#CCC#CCC#CCCCC(=O)O CHEMBL458328 Potency 631.0 nM
CSC1=N/C(=C\c2ccccc2C)C(=O)S1 CHEMBL1309429 Potency 631.0 nM
Oc1c(I)cc(Cl)c2cccnc12 CHEMBL497 Potency 631.0 nM
CN(C)c1ccc(N=Nc2cccc3ccoc23)cc1 CHEMBL1522796 Potency 631.0 nM
Cc1cc(C)c2ccc3c(C)c(C)[nH]c3c2n1 CHEMBL1325782 Potency 631.0 nM
CCCOc1ccc(CC(=O)NN=C(S)Nc2ccccc2)cc1Br CHEMBL1366888 Potency 631.0 nM
c1ccc(CN(CCN(Cc2ccccn2)Cc2ccccn2)Cc2ccccn2)nc1 CHEMBL1472575 Potency 631.0 nM
CCCCCOc1ccc(C(=O)OCC(=O)Nc2cc(C)on2)cc1 CHEMBL1433659 Potency 631.0 nM
COC(=O)C1=C(C(=O)OC)[C@@H]2N(C)c3ccccc3[C@@]23C[C@@H](C(=O)OC)N(S(=O)(=O)c2ccc(Br)cc2)C3=N1 CHEMBL1315981 Potency 631.0 nM
NC(=O)CCC(NC(=O)c1ccc(Cl)cc1)C(=O)NCCc1ccc2c(c1)OCCO2 CHEMBL1515978 Potency 631.0 nM
c1ccc2c(c1)OC[C@@H](C1=NCCN1)O2 CHEMBL1410804 Potency 631.0 nM
COC(=O)c1sc2nc3c(c(-c4cccs4)c2c1N)CCCC3 CHEMBL1382225 Potency 631.0 nM
O=C1OC2(c3cc(I)c(O)c(I)c3Oc3c2cc(I)c(O)c3I)c2c(Cl)c(Cl)c(Cl)c(Cl)c21 CHEMBL1160160 Potency 631.0 nM
O=C(O)C1CCc2sc3[nH]c(=S)n(-c4ccccc4)c(=O)c3c21 CHEMBL1518820 Potency 631.0 nM
Cc1ccc(C(=O)Nc2nc(-c3ccccn3)cs2)o1 CHEMBL1438684 Potency 631.0 nM
CCOc1cccc(/C=C2\NC(=S)N(c3ccccc3)C2=O)c1O CHEMBL3197703 Potency 631.0 nM
O=C(N/N=C/c1cn(Cc2cccc(F)c2)c2ccccc12)c1cc(O)cc(O)c1 CHEMBL1981446 Potency 631.0 nM
NS(=O)(=O)c1cccc2c1c([N+](=O)[O-])cc1nc(O)c(O)nc12 CHEMBL222519 Potency 631.0 nM
O=C(/C=C/c1ccccc1)NC(=S)NNC(=O)c1cnccn1 CHEMBL1301082 Potency 631.0 nM
O=C1c2ccccc2C(=O)N1/N=C/c1ccc(O)c(O)c1O CHEMBL3189657 Potency 631.0 nM
Cc1cc(NC(c2ccc(Cl)cc2)c2ccc3cccnc3c2O)no1 CHEMBL588804 Potency 631.0 nM
Nc1nc(-c2ccccc2)c(N=Nc2cccnc2)s1 CHEMBL1478443 Potency 631.0 nM
Cc1cc2ncn(-c3ncccc3[N+](=O)[O-])c2cc1C CHEMBL1341682 Potency 631.0 nM
COc1cccc(COCC(O)CN2CCC(C(N)=O)CC2)c1 CHEMBL1374798 Potency 631.0 nM
CCOC(=S)SCc1cn2ccc(C)cc2n1 CHEMBL1597701 Potency 631.0 nM
CCCOc1ccc(/C=N/Nc2ccccc2[N+](=O)[O-])c(OCCC)c1 CHEMBL3192144 Potency 631.0 nM
Cc1ccc(N=Nc2c(O)[nH]c3ccc(F)cc23)cc1 CHEMBL1432696 Potency 631.0 nM
CCOc1ccc(N2C(=O)NC(=O)/C(=N\Nc3c(C)n(C)n(-c4ccccc4)c3=O)C2=O)cc1 CHEMBL3199525 Potency 631.0 nM
Cc1ccc(C(=O)NCCCNC(=O)COc2ccc(Cl)cc2)cn1 CHEMBL1341804 Potency 707.9 nM
Cc1cc(SCNC(=O)c2ccccc2)ncn1 CHEMBL1528235 Potency 707.9 nM
CC(=O)Nc1ccc(S(=O)(=O)NNC(=O)C(=O)NNc2ccccn2)cc1 CHEMBL1363684 Potency 707.9 nM
N[C@@H](CCCP(=O)(O)O)C(=O)O CHEMBL71898 Potency 707.9 nM
O=C(Nc1nnc(-c2cccs2)o1)c1cccc(Oc2ccccc2)c1 CHEMBL1542886 Potency 707.9 nM
CN(C)[C@@H]1C(=O)C(C(=O)NCN2CCCC2)=C(O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)C3CC12 CHEMBL1504113 Potency 707.9 nM
CC1CCCCN1C(=O)CSc1nnc(-c2ccccc2O)o1 CHEMBL1306262 Potency 707.9 nM
COc1cc(O)c2c(c1)oc(=O)c1c3cc(O)c(O)cc3oc21 CHEMBL97453 Potency 707.9 nM
C[C@H](NS(=O)(=O)c1ccc2c(c1)OCCCO2)C(=O)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1442519 Potency 707.9 nM
Cc1ccc(C(=O)COC(=O)CN2C(=O)C3C4C=CC(C4)C3C2=O)cc1[N+](=O)[O-] CHEMBL1404003 Potency 707.9 nM
O=C(c1ccccc1)c1c(O)nc2cccc3c2c1-c1ccccc1C3=O CHEMBL1364416 Potency 707.9 nM
COc1ccc(/N=C2C(=N\c3ccc(OC)cc3)/N(c3ccc(OC)cc3)C(=S)N/2C(=O)c2ccc(OC)cc2)cc1 CHEMBL3208674 Potency 707.9 nM
O=C1/C(=C/C=C/c2ccco2)SC(=S)N1NS(=O)(=O)c1ccccc1 CHEMBL1416439 Potency 707.9 nM
O=C(Nc1nnc(-c2ccc(Cl)cc2)o1)c1nc2ccccc2s1 CHEMBL1347204 Potency 707.9 nM
CC(=O)c1c(C)[nH]c(C(=O)NNC(=O)c2ccc(C)cc2)c1C CHEMBL1591288 Potency 707.9 nM
Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21 CHEMBL121663 Potency 707.9 nM
CC(Oc1ccc(F)cc1)C(=O)Oc1ccc(N(C)S(=O)(=O)c2ccccc2)cc1 CHEMBL1535577 Potency 707.9 nM
CCOC(=O)c1cnc(-n2[nH]c(C)cc2=O)[nH]c1=O CHEMBL3144988 Potency 707.9 nM
O=C(O)C1CCCCN1C(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1 CHEMBL1524723 Potency 707.9 nM
CN(C)S(=O)(=O)N1CCCC(C(=O)c2ccc(-c3ccccc3)c(F)c2)C1 CHEMBL1583148 Potency 707.9 nM
Cc1c(C(=O)O)c(O)cc2c1C(=O)c1c(O)c([C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(O)c(O)c1C2=O CHEMBL1366408 Potency 707.9 nM
CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3ccc(F)cc3)CC1)C(=O)CO2 CHEMBL1553083 Potency 707.9 nM
Cc1csc(SCC(=O)Nc2ccc(F)cc2Cl)n1 CHEMBL1600171 Potency 707.9 nM
COc1ccc2cc1Oc1ccc(cc1)C[C@H]1c3cc(c(OC)cc3CCN1C)Oc1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3 CHEMBL176045 Potency 707.9 nM
Cc1cccc(-c2cc(=O)c3cc(C)ccc3o2)c1 CHEMBL137498 Potency 707.9 nM
O=C(Nc1nnc(-c2ccccc2)o1)c1cc(-c2cccs2)nc2ccccc12 CHEMBL1348119 Potency 707.9 nM
CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1 CHEMBL29097 Potency 707.9 nM
O=C(CCc1ccccc1)NNC(=O)c1ccncc1 CHEMBL1511824 Potency 707.9 nM
O=C1NC(=S)S/C1=C\C=C\c1ccc([N+](=O)[O-])o1 CHEMBL69612 Potency 707.9 nM
O=C(Nc1ccncc1)C1CCN(S(=O)(=O)c2ccccc2)CC1 CHEMBL1523212 Potency 707.9 nM
Cc1cc(C(=O)NNC(S)=NC(C)c2ccccc2)c2ccccc2n1 CHEMBL1563219 Potency 707.9 nM
Cc1cc(C(=O)N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O)c2ccccc2n1 CHEMBL3190468 Potency 707.9 nM
COc1ccc2nc(N=Nc3c(O)ccc4ccccc34)sc2c1 CHEMBL1586534 Potency 707.9 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL567 Potency 707.9 nM
CCSc1nc2c(cnn2-c2ccccc2)c(=O)n1N CHEMBL1409185 Potency 707.9 nM
C=C1c2c(Cl)ccc(O)c2C(=O)C2=C(O)[C@@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12 CHEMBL1596361 Potency 707.9 nM
O=C1NN=COc2ccccc21 CHEMBL1440375 Potency 707.9 nM
O=C(N/N=C/c1cc([N+](=O)[O-])cc(Br)c1O)C12CC3CCC(CC(C3)C1)C2 CHEMBL3195778 Potency 707.9 nM
CC(O)CSc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1Cl CHEMBL1321557 Potency 707.9 nM
Cc1ccccc1-n1c(S)nnc1-c1cccnc1 CHEMBL1566418 Potency 707.9 nM
COc1cccc(CNC(=O)c2nnn(CC(=O)Nc3c(C)cccc3C)c2N)c1 CHEMBL1422842 Potency 707.9 nM
Cc1cc(/C=N/n2c(COc3ccccc3)nc3ccccc3c2=O)c(O)c([N+](=O)[O-])c1 CHEMBL1974450 Potency 707.9 nM
COc1ccc(NC(=O)CSc2sc3c(O)cc(O)nc3c2C#N)c(OC)c1 CHEMBL1540637 Potency 707.9 nM
CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nnc(-c4ccc5c(c4)CCCC5)o3)cc2)CC(C)O1 CHEMBL1609264 Potency 707.9 nM
COc1cccc(/C=N/NC(=O)c2nc(-c3ccccc3)cc(-c3ccccc3)n2)c1O CHEMBL3190720 Potency 707.9 nM
CCN=C(S)NNC(=O)c1cc(-c2cccc(C)c2)nc2ccccc12 CHEMBL1603982 Potency 707.9 nM
C/C=C\C1=C(CO)C(=O)[C@@H]2O[C@H]2C1=O CHEMBL2373648 Potency 707.9 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=S)Nc3ccccc3)CCC[C@]21C CHEMBL4560013 IC50 710.0 nM
O=C1NC(=S)NC(=O)C1=Cc1ccco1 CHEMBL4537015 IC50 710.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccccc1)C4=O CHEMBL4237606 IC50 720.0 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)Nc3cccc(Br)c3)C(=O)C12C CHEMBL4069136 IC50 750.0 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)NCCc3ccc(O)cc3)C(=O)[C@@]12C CHEMBL4102274 IC50 790.0 nM
O=C(Cc1c(F)cccc1Cl)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1 CHEMBL1374941 Potency 794.3 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H](C(=O)O)[C@@H](OC(=O)/C=C/c1ccc(O)c(O)c1)C(=O)O CHEMBL282731 Potency 794.3 nM
COc1ccc(-c2nnc(NC(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)o2)cc1 CHEMBL1503006 Potency 794.3 nM
CC(=O)N1CCN(C)CC1 CHEMBL575239 Potency 794.3 nM
CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C(C(=O)[O-])=C(CSc4nnnn4C)CSC23)c2ccc(O)cc2)C(=O)C1=O CHEMBL1572125 Potency 794.3 nM
N#Cc1ccccc1NC(=O)C1SC(Nc2ccccc2)=C(c2nc3ccccc3s2)C1=N CHEMBL1336187 Potency 794.3 nM
Cc1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 CHEMBL1376870 Potency 794.3 nM
C=C(C)Cn1c(S)nnc1-c1cccs1 CHEMBL1388851 Potency 794.3 nM
O=C(COC(=O)c1cc(O)nc2ccccc12)NCCc1ccccc1 CHEMBL1318373 Potency 794.3 nM
CCCC(C)(COC(N)=O)COC(=O)NC(C)C CHEMBL1233 Potency 794.3 nM
Cc1ccccc1NC(S)=NNC(=O)c1csc2c1CCC(C)C2 CHEMBL1496413 Potency 794.3 nM
Cc1nnc2ccc(-c3cccc(C(F)(F)F)c3)nn12 CHEMBL13662 Potency 794.3 nM
Cc1ccnc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 CHEMBL1593445 Potency 794.3 nM
CC(C)C(C(=O)O)N1C(=O)/C(=C/C=C/c2ccco2)SC1=S CHEMBL257359 Potency 794.3 nM
CCSC1=N/C(=C\c2cccc(F)c2)C(=O)S1 CHEMBL1427314 Potency 794.3 nM
Cc1ccc(-c2nnc(NC(=O)c3ccc([N+](=O)[O-])o3)o2)c(C)c1 CHEMBL1474564 Potency 794.3 nM
Nc1ccc2nc3c(O)nc(S)nc3nc2c1 CHEMBL1429070 Potency 794.3 nM
O=C(O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1-c1c2cc(I)c(=O)c(I)c-2oc2c(I)c(O)c(I)cc12 CHEMBL1208422 Potency 794.3 nM
Clc1ccc(C2=CCC[C@H]3CC[C@@H]2N3)cn1 CHEMBL1405034 Potency 794.3 nM
COc1ccc(/C=C/C(=O)c2ccc(C)s2)cc1 CHEMBL1561854 Potency 794.3 nM
O=C(CSc1nc2ccccc2n1CCc1ccccc1)c1ccc(O)c(O)c1 CHEMBL1406195 Potency 794.3 nM
CCOC(=O)c1ccc(NC(=S)N2CCSC2c2ccc(Cl)cc2)cc1 CHEMBL1585488 Potency 794.3 nM
O=[N+]([O-])c1ccccc1S(=O)(=O)N(CC(O)CN1CCCCC1)c1ccccc1 CHEMBL1365562 Potency 794.3 nM
CCc1cccc(NC(=O)CCc2nc(O)c3c4c(sc3n2)CCCC4)c1 CHEMBL1483800 Potency 794.3 nM
CCc1ccc(-n2c(C)nnc2S)cc1 CHEMBL1427844 Potency 794.3 nM
CC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccco1 CHEMBL1547238 Potency 794.3 nM
CNCC(O)c1ccc(O)c(O)c1 CHEMBL1740 Potency 794.3 nM
N#C/C(C(N)=O)=c1/ccc2c(c1)N1C3=C(CCCC3)CC3CCCCC31N=2 CHEMBL3184468 Potency 794.3 nM
Cc1ccc(N2C(=O)CC(Sc3nc[nH]n3)C2=O)cc1 CHEMBL1612805 Potency 794.3 nM
O=C(Cc1ccc(Cl)c(Cl)c1)N1CCCC[C@H]1CN1CCCC1 CHEMBL71294 Potency 794.3 nM
C[C@@](N)(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL1452561 Potency 794.3 nM
O=C(NN1C(=O)CSC1=S)C(=O)NN1C(=O)CSC1=S CHEMBL1594374 Potency 794.3 nM
COC(=O)C(N)Cc1ccc(O)c(O)c1 CHEMBL1439696 Potency 794.3 nM
Cc1cc(NC(=O)c2c(F)cccc2F)n(-c2nc3ccccc3[nH]2)n1 CHEMBL1490656 Potency 794.3 nM
CCN(Cc1ccccc1)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3ccccc3OC)o2)cc1 CHEMBL1300080 Potency 794.3 nM
COc1cccc2sc(Nc3nnc(-c4cccs4)o3)nc12 CHEMBL1333386 Potency 794.3 nM
CCOc1ccc(NC(=O)c2cccc(-n3cccc3)c2)cc1S(=O)(=O)N1CCOCC1 CHEMBL1558195 Potency 794.3 nM
COc1ccc(S(=O)(=O)N2CCc3ccccc32)cc1C(=O)NCc1ccco1 CHEMBL1590690 Potency 794.3 nM
CCOC(=O)C(=O)NNc1ccc(F)cc1 CHEMBL1461458 Potency 794.3 nM
CCS(=O)(=O)c1cc([N+](=O)[O-])c(Sc2ccccc2N)s1 CHEMBL1422806 Potency 794.3 nM
CC(C)Oc1cccc(-n2c(CCc3c[nH]c4ccc(Br)cc34)nc3ccccc3c2=O)c1 CHEMBL37312 Potency 794.3 nM
CCCn1c(=O)c(C(=O)NNS(=O)(=O)c2ccc(Cl)cc2)c(O)c2ccccc21 CHEMBL1423656 Potency 794.3 nM
O=C(O)/C=C/c1ccc(O)c(O)c1 CHEMBL145 Potency 794.3 nM
CN(C)c1ccc(/N=C2\C(=O)N(C)c3cccc4c(O)c5ccccc5c2c34)cc1 CHEMBL2000619 Potency 794.3 nM
Oc1ccc2ccccc2c1N=Nc1nccs1 CHEMBL1511179 Potency 794.3 nM
CCOC(=O)c1ccc(NC(=S)N2CCSC2c2ccc(Br)cc2)cc1 CHEMBL1526099 Potency 794.3 nM
CCCOc1cccc(-c2cc(C(=O)NN=C(S)NCC)c3ccccc3n2)c1 CHEMBL1353757 Potency 794.3 nM
CCOC(=O)c1ccc(N/N=C/c2cc(Br)cc([N+](=O)[O-])c2O)cc1 CHEMBL3193923 Potency 794.3 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccncc1)C4=O CHEMBL3356740 IC50 810.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccc(C)s1)C4=O CHEMBL4237693 IC50 840.0 nM
Cc1c(CC(=O)NC(Cc2ccc(Cl)cc2)C(=O)O)c(=O)oc2c(C)c3occ(-c4ccc(F)cc4)c3cc12 CHEMBL4637317 IC50 850.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccccn1)C4=O CHEMBL4238219 IC50 860.0 nM
O=C1NC(=S)/C(=C/c2ccc(O)c(O)c2O)S1 CHEMBL2170127 IC50 870.0 nM
COc1ccc(C(=O)NC(=S)NNC(=O)c2cnccn2)cc1OC CHEMBL1408115 Potency 891.3 nM
O=C(/C=C/c1ccccc1)c1cc(Br)ccc(=O)c1O CHEMBL1418885 Potency 891.3 nM
COCCc1ccc(OCC(O)CNC(C)C)cc1 CHEMBL2062335 Potency 891.3 nM
COc1cc(C(=O)NC(=S)NNC(=O)[C@H]2C[C@@H]2c2ccccc2)cc(OC)c1OC CHEMBL1462653 Potency 891.3 nM
CCN1C(=O)C(=CNNC(=O)c2ccccc2)C(=O)N(CC)C1=S CHEMBL1559308 Potency 891.3 nM
CSc1nc(NC2CCCC2)c([N+](=O)[O-])c(NC2CCCC2)n1 CHEMBL392394 Potency 891.3 nM
CCOC(=O)Cc1csc(NC(=S)NC(=O)c2cc(OC)cc(OC)c2)n1 CHEMBL1330854 Potency 891.3 nM
CCCCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O CHEMBL101 Potency 891.3 nM
Cc1ccc(NC(=S)c2nc3ccccc3[nH]2)cc1 CHEMBL1305918 Potency 891.3 nM
CCOC(=O)c1ccc(NC(=O)CC2Sc3ncnn3C2=O)cc1 CHEMBL398233 Potency 891.3 nM
Cc1c2cc(O)c(=O)cc-2oc2cc(O)c(O)cc12 CHEMBL175266 Potency 891.3 nM
Cc1ccccc1C(=O)NNC(=S)NC(=O)c1ccc(Cl)cc1Cl CHEMBL1416096 Potency 891.3 nM
O=C(Nc1ccccc1C(=O)NC1CC1)c1ccc([N+](=O)[O-])o1 CHEMBL1455019 Potency 891.3 nM
O=C(O)c1cc(O)c2c(Cl)cc(Cl)cc2n1 CHEMBL50267 Potency 891.3 nM
O=C(/C=C/c1ccc2c(c1)OCCCO2)c1ccc2ccccc2c1O CHEMBL1347030 Potency 891.3 nM
Cc1onc(-c2ccccc2)c1C(=O)NNC(=S)NC(=O)/C=C/c1cccs1 CHEMBL1494996 Potency 891.3 nM
O=c1oc2ccccc2c(O)c1Cc1cc(Cl)c2cccnc2c1O CHEMBL1307271 Potency 891.3 nM
O=C(/C=C/c1ccc(Br)cc1)NC(=S)NNC(=O)c1ccco1 CHEMBL1509051 Potency 891.3 nM
CN(CCc1ccc(Cl)c(Cl)c1)[C@H]1CCCC[C@H]1N1CCCC1 CHEMBL106437 Potency 891.3 nM
CCOC(=O)CCCc1ccc(/C(C)=N/NC(N)=S)cc1 CHEMBL3197927 Potency 891.3 nM
O=C1c2ccccc2C(=O)c2c(Nc3ccc(CCO)cc3)ccc(O)c21 CHEMBL1509338 Potency 891.3 nM
CCOC(=O)c1c(NC(=O)CSc2nnnn2-c2ccc(OC)cc2)sc(C)c1C CHEMBL1430796 Potency 891.3 nM
CCN1C(=O)N[C@@H](CCc2ccccc2)[C@@H](C(=O)OC)[C@H]1C CHEMBL1441665 Potency 891.3 nM
O=C(CSc1cc(Cl)ccc1Cl)NC1CCCC1 CHEMBL1348165 Potency 891.3 nM
CCCC(=O)NC(c1cccs1)c1cc([N+](=O)[O-])c2cccnc2c1O CHEMBL1546767 Potency 891.3 nM
O=C1C=CC(=O)C(Cl)=C1 CHEMBL1373950 Potency 891.3 nM
Cc1ccc(NC(=O)CN2C(=O)N/C(=C/c3cccn3-c3ccc(C(=O)O)cc3)C2=O)cc1 CHEMBL1427775 Potency 891.3 nM
COc1cc([N+](=O)[O-])cc(/C=N/NC(=O)C(C)Nc2ccccc2C)c1O CHEMBL3196020 Potency 891.3 nM
Cc1ccc(C)c(NC(=S)N/N=C2\CCc3ccccc32)c1 CHEMBL3196408 Potency 891.3 nM
O=C(NNC(=S)Nc1ccccc1)c1cccc(Br)c1 CHEMBL1392702 Potency 891.3 nM
COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(-n3[nH]c(=O)c(C)c3C)n2)cc1 CHEMBL1564501 Potency 891.3 nM
CC(C)(C)Sc1ccc([N+](=O)[O-])cc1C(=O)Nc1ccncc1 CHEMBL1510722 Potency 891.3 nM
Cc1cnc(C(=O)Oc2ccc(-c3ccccc3)cc2)cn1 CHEMBL1510657 Potency 891.3 nM
O=c1cc(-c2ccccc2)[nH]n1-c1nc2ccccc2s1 CHEMBL3145107 Potency 891.3 nM
CC(=O)Nc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 CHEMBL116879 Potency 891.3 nM
Cc1cc(C)c2c(=O)n(CC(=O)NCCCN3CCOCC3)sc2n1 CHEMBL1499996 Potency 891.3 nM
CC(=O)OC1CC2C(C)(C)C(=O)C=C[C@]2(C)C2CC[C@]3(C)C(=CC(=O)OC3c3ccoc3)[C@]12C CHEMBL1440056 Potency 891.3 nM
O=C(/C=C/c1ccc(O)c(O)c1)OC(Cc1ccc(O)c(O)c1)C(=O)O CHEMBL66966 Potency 891.3 nM
N#CC(=Cc1ccc(O)c(O)c1)C(N)=S CHEMBL1408526 Potency 891.3 nM
COC(=O)C1=C(C(=O)OC)SC(=C2C(=S)C(C)(C)N(C(=O)CC(C)C)c3ccccc32)S1 CHEMBL1361153 Potency 891.3 nM
Cc1cc(C)c2sc(NNC(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)nc2c1 CHEMBL1500469 Potency 891.3 nM
O=[N+]([O-])c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL168276 Potency 891.3 nM
COc1cccc2sc(Nc3nnc(-c4ccccc4Cl)o3)nc12 CHEMBL1569543 Potency 891.3 nM
COC(=O)c1ccc(CN2C(=O)C3CCCCC3C2=O)o1 CHEMBL1527588 Potency 891.3 nM
N#CC(C#N)=c1ccc2c(c1)N1C3=C(CCCC3)CC3CCCCC31N=2 CHEMBL1570159 Potency 891.3 nM
COC(=O)C1=C(C)N(Cc2ccccc2)C(=O)N[C@H]1c1ccc(Br)cc1 CHEMBL1408835 Potency 891.3 nM
O=C(/C=C/c1ccc(F)cc1)NC(=S)NNC(=O)c1cnccn1 CHEMBL1383414 Potency 891.3 nM
CCOC(=O)c1sc2nccc(N(C)C)c2c1N=CNOCc1c(F)cccc1Cl CHEMBL1480313 Potency 891.3 nM
CC(C)CCNC(=O)CN(Cc1ccc(F)cc1)C(=O)CCC(=O)Nc1ccccn1 CHEMBL1384036 Potency 891.3 nM
C[C@@H]1O[C@@H](Oc2c(-c3cc(O)c(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@H](O)[C@H](O)[C@H]1O CHEMBL522983 Potency 891.3 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1cccs1)C4=O CHEMBL4247712 IC50 900.0 nM
CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)/C(=C(/C)Nc3ccc(F)cc3)C(=O)[C@]12C CHEMBL2207621 IC50 940.0 nM
CC(C)c1ccc2c(c1)CC[C@H]1[C@](C)(CNC(=O)Nc3ccccc3)CCC[C@]21C CHEMBL4440022 IC50 950.0 nM
CC(=O)C1=C(O)C=C2Oc3c4c(c(C)c(O)c3[C@@]2(C)C1=O)O/C(=C\c1ccc(F)cc1)C4=O CHEMBL4241774 IC50 980.0 nM
O=C(NCCc1c[nH]c2ccccc12)c1cc2c([nH]c3ccccc32)c(-c2ccc3c(c2)OCO3)n1 CHEMBL4636462 IC50 980.0 nM