CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 CHEMBL65 IC50 0.0 nM
CS(=O)(=O)Nc1cccc(-n2c3nc(=O)n(-c4ccc(Cl)cc4)c(=O)c-3cc3ccc(C#N)cc32)c1 CHEMBL4441013 IC50 6.1 nM
CS(=O)(=O)Nc1ccc(-n2c3nc(=O)n(-c4ccc(Cl)cc4)c(=O)c-3cc3ccc(C#N)cc32)cc1 CHEMBL4572376 IC50 6.5 nM
N#Cc1ccc2cc3c(=O)n(-c4ccc(Cl)cc4)c(=O)nc-3n(-c3cccc(O)c3)c2c1 CHEMBL4436202 IC50 7.3 nM
N#Cc1ccc2cc3c(=O)n(-c4ccc(Cl)c(Cl)c4)c(=O)nc-3n(-c3cccc(O)c3)c2c1 CHEMBL4587441 IC50 14.0 nM
N#Cc1ccc2cc3c(=O)n(-c4cccc(Cl)c4)c(=O)nc-3n(-c3cccc(O)c3)c2c1 CHEMBL4520052 IC50 20.0 nM
CS(=O)(=O)Nc1cccc(-n2c3nc(=O)[nH]c(=O)c-3cc3ccc(C#N)cc32)c1 CHEMBL2420474 EC50 30.0 nM
N#Cc1ccc2cc3c(=O)n(-c4ccccc4)c(=O)nc-3n(-c3ccc(O)cc3)c2c1 CHEMBL4560735 IC50 33.0 nM
N#Cc1ccc2cc3c(=O)n(-c4ccc(Cl)cc4)c(=O)nc-3n(-c3ccc(O)cc3)c2c1 CHEMBL4468174 IC50 33.0 nM
N#Cc1ccc2cc3c(=O)n(-c4cccc(C(N)=O)c4)c(=O)nc-3n(-c3ccc(O)cc3)c2c1 CHEMBL4555612 IC50 35.0 nM
COC(=O)c1cccc(-n2c(=O)nc3n(-c4ccc(O)cc4)c4cc(C#N)ccc4cc-3c2=O)c1 CHEMBL4521151 IC50 38.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(-c4nnn[nH]4)c3)c2c1 CHEMBL2420480 EC50 40.0 nM
NC1=CC(N)=C2C=CC(=O)N=C2C1=O CHEMBL4470500 IC50 40.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(O)c3)c2c1 CHEMBL2420507 IC50 42.0 nM
COc1ccc(-c2csc(-c3nc4c(=O)n(C)c(=O)nc-4n(C)n3)c2)cc1OC CHEMBL2420481 EC50 50.0 nM
N#Cc1ccc2cc3c(=O)n(-c4ccc(Br)cc4)c(=O)nc-3n(-c3ccc(O)cc3)c2c1 CHEMBL4457155 IC50 65.0 nM
N#Cc1ccc2cc3c(=O)n(-c4ccc(F)cc4)c(=O)nc-3n(-c3ccc(O)cc3)c2c1 CHEMBL4546104 IC50 70.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(N)c3)c2c1 CHEMBL2420472 EC50 90.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(O)cc3)c2c1 CHEMBL2420465 EC50 90.0 nM
Cn1nc(-c2cc(-c3ccccc3)cs2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420614 EC50 120.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(OCc4cccc(C(=O)O)c4)cc3)c2c1 CHEMBL4518508 IC50 130.0 nM
Cn1nc(-c2ccc3ccccc3c2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420610 EC50 150.0 nM
COC(=O)c1cccc(COc2ccc(-n3c4nc(=O)[nH]c(=O)c-4cc4ccc(C#N)cc43)cc2)c1 CHEMBL4576353 IC50 150.0 nM
CCCc1nc2c(=O)n(C)c(=O)nc-2n(C)n1 CHEMBL1325945 IC50 161.1 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(Oc4cccc(C(=O)O)c4)cc3)c2c1 CHEMBL4557001 IC50 190.0 nM
Cn1nc(-c2cc(Br)cs2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420613 EC50 200.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(OCc4ccccc4)cc3)c2c1 CHEMBL4464179 IC50 200.0 nM
Cn1nc(-c2ccccn2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1463659 IC50 210.04 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(CO)c3)c2c1 CHEMBL2420466 EC50 250.0 nM
Cc1csc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)c1 CHEMBL2420612 EC50 250.0 nM
Cn1nc(-c2ccc(OC(F)(F)F)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420616 EC50 260.0 nM
N#Cc1ccc2cc3c(=O)n(-c4ccc(Cl)cc4)c(=O)nc-3n(-c3ccccc3)c2c1 CHEMBL4471861 IC50 270.0 nM
CCCn1nc(-c2ccc(CC)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2417582 EC50 280.0 nM
CCc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1 CHEMBL2420615 EC50 280.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(S(N)(=O)=O)c3)c2c1 CHEMBL2420477 EC50 290.0 nM
Cc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1 CHEMBL1450796 EC50 290.0 nM
CCc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(CC)n2)cc1 CHEMBL1569025 EC50 300.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(Oc4ccccc4)c3)c2c1 CHEMBL4536546 IC50 300.0 nM
COc1ccc(-n2c3nc(=O)[nH]c(=O)c-3cc3ccc(C#N)cc32)cc1O CHEMBL2420469 EC50 320.0 nM
Cn1c(=O)nc2n(-c3ccc(O)cc3)c3cc(C#N)ccc3cc-2c1=O CHEMBL4444838 IC50 320.0 nM
Cn1nc(-c2ccc(C(F)(F)F)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1096283 EC50 330.0 nM
CCc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(CC3CC3)n2)cc1 CHEMBL2420509 EC50 360.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc4[nH]ncc34)c2c1 CHEMBL2420479 EC50 370.0 nM
Cn1nc(C2CC2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420515 EC50 370.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(OCc4ccccc4)c3)c2c1 CHEMBL4590491 IC50 380.0 nM
Cc1cccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)c1 CHEMBL2420617 EC50 400.0 nM
Cn1nc(C2CCOCC2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420518 EC50 430.0 nM
Cn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1334062 EC50 430.0 nM
COc1cccc(-n2c3nc(=O)[nH]c(=O)c-3cc3ccc(C#N)cc32)c1 CHEMBL2420467 EC50 470.0 nM
O=c1nc2n(-c3cccc(O)c3)c3cc(Cl)ccc3cc-2c(=O)[nH]1 CHEMBL2420503 EC50 480.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccccc3)c2c1 CHEMBL2420506 EC50 500.0 nM
CN1CCN(C2=C(Cl)C(=O)c3ccccc3C2=O)CC1 CHEMBL1163377 IC50 581.05 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc4cn[nH]c4c3)c2c1 CHEMBL2420478 EC50 640.0 nM
Cn1nc(C2CCCC2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420516 EC50 640.0 nM
CCc1ccc(-c2nc3c(=O)[nH]c(=O)nc-3n(C)n2)cc1 CHEMBL2420512 EC50 670.0 nM
Cn1nc(CCc2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420609 EC50 680.0 nM
O=C1C(Nc2ccc(O)cc2)=C/C(=N/S(=O)(=O)c2cccs2)c2ccccc21 CHEMBL2000517 IC50 697.64 nM
CCc1ccc(-c2nc3c(=O)n(Cc4ccccc4)c(=O)nc-3n(C)n2)cc1 CHEMBL2420514 EC50 700.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3cccc(CC(N)=O)c3)c2c1 CHEMBL2420473 EC50 720.0 nM
Cn1nc(C2CCCCC2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420517 EC50 750.0 nM
Cn1nc(-c2cscn2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2420611 EC50 770.0 nM
Cn1nc(-c2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1527391 EC50 780.0 nM
O=C(O)c1ccc(NC2=C/C(=N/S(=O)(=O)c3cccs3)c3ccccc3C2=O)cc1 CHEMBL1877709 IC50 816.81 nM
COC1=CC(=O)c2c(ccc3ncnc(N)c23)C1=O CHEMBL1728280 IC50 842.48 nM
COc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1OC CHEMBL2094689 EC50 870.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(OC(F)F)cc3)c2c1 CHEMBL4470162 IC50 880.0 nM
CCOC(=O)c1c(C)[nH]c2c1-c1ccccc1C(=O)C2=O CHEMBL1384253 IC50 915.0 nM
COC(=O)c1cccc(Oc2ccc(-n3c4nc(=O)[nH]c(=O)c-4cc4ccc(C#N)cc43)cc2)c1 CHEMBL4585923 IC50 930.0 nM
Cn1nc(Cc2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1394266 EC50 960.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc4c(c3)OCO4)c2c1 CHEMBL4470609 IC50 960.0 nM
CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O CHEMBL15192 IC50 970.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(OCc4cccc(Cl)c4)cc3)c2c1 CHEMBL4473892 IC50 990.0 nM
COc1cnc2c(c1)C(=O)c1c-2n(CCCN2CCC(N)CC2)c(=O)c2cc([N+](=O)[O-])ccc12 CHEMBL4061238 IC50 1000.0 nM
COc1cc2c3c(n(CCCNCCO)c(=O)c2cc1OC)-c1cc2c(cc1C3=O)OCO2 CHEMBL126159 IC50 1000.0 nM
N#Cc1ccc2cc3c(=O)[nH]c(=O)nc-3n(-c3ccc(OC(F)(F)F)cc3)c2c1 CHEMBL4449643 IC50 1000.0 nM