C=CC(=O)N1CC(c2nc(-c3ccc(OC(F)(F)F)cc3)c3ncn(C)c3n2)C1 CHEMBL5401444 IC50 2.0 nM
C=CC(=O)N1CC(c2nc(-c3ccc(OC(F)(F)F)cc3)c3ncsc3n2)C1 CHEMBL5422959 IC50 2.0 nM
Cn1cnc2c(-c3ccc(OC(F)(F)F)cc3)nc(C3CN(C(=O)C4=CCC4)C3)nc21 CHEMBL5400400 IC50 2.0 nM
C=C(Cl)C(=O)NCc1nn(-c2ccc(OC(F)(F)F)cc2)c2nccc(CO)c12 CHEMBL5408536 IC50 2.0 nM
C#CC(=O)NCc1nn(-c2ccc(OC(F)(F)F)cc2)c2nccc(CO)c12 CHEMBL5403826 IC50 2.0 nM
C=CS(=O)(=O)NCc1cc(-c2ccc(OC(F)(F)F)cc2)c2c(c1CO)CCO2 CHEMBL5419829 IC50 3.0 nM
C=CC(=O)NCc1cc(-c2ccc(OC(F)(F)F)cc2)c2ncn(C)c2c1C#CCO CHEMBL5416415 IC50 3.0 nM
C=CC(=O)N(C)Cc1cc(-c2ccc(OC(F)(F)F)cc2)c2c(c1CO)CCO2 CHEMBL5415215 IC50 3.0 nM
CN(Cc1nn(-c2ccc(OC(F)(F)F)cc2)c2ccccc12)C(=O)CCl CHEMBL5438256 IC50 3.0 nM
C=CC(=O)N1CC(c2nn(-c3ccc(OC(F)(F)F)cc3)c3nccc(CO)c23)C1 CHEMBL5432828 IC50 3.0 nM
O=C(/C=C/CO)N1CC(c2nn(-c3ccc(OC(F)(F)F)cc3)c3nccc(Cl)c23)C1 CHEMBL5428867 IC50 3.0 nM
N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2cc(Cl)ccc12)NC(=O)[C@@H]1CCCN1)C(=O)NC1(C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2CCC2)C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2cccc3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N2CCC[C@H]2C(=O)O)CC1 CHEMBL4567546 IC50 9.0 nM
C#Cc1ccnc2c1c(C1CN(C(=O)C=C)C1)nn2-c1ccc(OC(F)(F)F)cc1 CHEMBL5411200 IC50 9.0 nM
CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2cc(Cl)ccc12)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1CCC1)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)O CHEMBL4468725 IC50 16.0 nM
CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2cc(Cl)ccc12)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1CCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)O CHEMBL4467555 IC50 45.0 nM
CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O)C(C)C)[C@@H](C)O)C(C)C)[C@@H](C)O CHEMBL4476332 IC50 56.0 nM
O=c1cc(CO)oc(C(Nc2ccccc2)c2ccccc2)c1O CHEMBL242708 IC50 70.0 nM
O=c1cc(CO)oc(C(Nc2ccccc2)c2ccccc2F)c1O CHEMBL4787565 IC50(app) 100.0 nM
C=CS(=O)(=O)Nc1ccc(Cc2ccc3ccccc3c2)cc1 CHEMBL4459587 IC50 197.0 nM
O=c1cc(CO)oc(C(Nc2ccccc2)c2ccc3ccccc3c2)c1O CHEMBL4776143 IC50(app) 200.0 nM
CC(C)c1ccc(C(Nc2ccccc2)c2oc(CO)cc(=O)c2O)cc1 CHEMBL4757924 IC50(app) 200.0 nM
O=c1cc(CO)oc(C(Nc2ccccc2)c2ccc(Br)cc2)c1O CHEMBL4745853 IC50(app) 200.0 nM
Cc1ccc(C(Nc2ccccc2)c2oc(CO)cc(=O)c2O)cc1 CHEMBL4757369 IC50(app) 200.0 nM
O=c1cc(CO)oc(C(Nc2cccc(F)c2)c2ccccc2)c1O CHEMBL4745831 IC50(app) 200.0 nM
COc1ccc2c(c1Nc1cccc(C(F)(F)F)c1)CN(C#N)C2 CHEMBL5405832 IC50 200.0 nM
CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2cc(Cl)ccc12)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1CCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O CHEMBL4514336 IC50 216.0 nM
O=c1cc(CO)oc(C(Nc2ccccn2)c2ccccc2F)c1O CHEMBL1701986 IC50(app) 300.0 nM
O=c1cc(CO)oc(C(Nc2ccccc2)c2ccc(F)cc2)c1O CHEMBL4789889 IC50(app) 300.0 nM
NC(=O)c1ccc(C(Nc2ccccc2)c2oc(CO)cc(=O)c2O)cc1 CHEMBL4797833 IC50(app) 300.0 nM
NC(=O)c1ccc(NC(c2ccccc2)c2oc(CO)cc(=O)c2O)cc1 CHEMBL4750726 IC50(app) 300.0 nM
Cc1ccnc(NC(c2ccccc2)c2oc(CO)cc(=O)c2O)c1 CHEMBL4783341 IC50(app) 300.0 nM
O=c1cc(CO)oc(C(Nc2ccccn2)c2ccccc2)c1O CHEMBL4744235 IC50(app) 300.0 nM
O=c1cc(CO)oc(C(Nc2ccccn2)c2ccc(Br)cc2)c1O CHEMBL4800702 IC50(app) 400.0 nM
O=c1cc(CO)oc(C(NCc2ccccc2)c2ccccc2)c1O CHEMBL4750624 IC50(app) 400.0 nM
N#CN1CC2CCCC(Nc3cccc(C(F)(F)F)c3)C2C1 CHEMBL5424157 IC50 400.0 nM
CCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2cc(Cl)ccc12)NC(=O)[C@@H]1CCCN1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cccc2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O CHEMBL4436894 IC50 409.0 nM
Cc1ccc2nc(Cn3cc(CN(C(=O)CCC(=O)OC(C)(C)C)C(C(=O)N[C@H]4C[C@@H]5CC[C@@]4(C)C5(C)C)c4c[nH]c5cc(Cl)ccc45)nn3)cn2c1 CHEMBL5436703 IC50 410.0 nM
O=c1cc(CO)oc(C(Nc2ccccc2)c2ccccn2)c1O CHEMBL4757939 IC50(app) 500.0 nM
Cc1ccn2cc(Cn3cc(CN(C(=O)CCC(=O)OC(C)(C)C)C(C(=O)NC4CC5CCC4(C)C5(C)C)c4c[nH]c5cc(Cl)ccc45)nn3)nc2c1 CHEMBL5220985 IC50 510.0 nM
N#CN1Cc2ccc(F)c(Nc3cccc(C(F)(F)F)c3)c2C1 CHEMBL5432067 IC50 600.0 nM
O=C(CCl)c1ccccc1Nc1cccc(C(F)(F)F)c1 CHEMBL4763473 IC50(app) 800.0 nM
O=c1cc(CO)oc(C(c2ccccc2)N2Cc3ccccc3C2)c1O CHEMBL4784286 IC50(app) 900.0 nM