Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc5c(c4)OCO5)cc3)cc2n1 CHEMBL4087541 IC50 0.13 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc3)cc2n1 CHEMBL4103584 IC50 0.16 nM
COc1ccc(-c2ccc(Cn3cc(-c4ccc(C)cc4)nn3)cc2)cn1 CHEMBL4449700 IC50 0.26 nM
Clc1cccc(-c2cn(Cc3ccc(-c4cccnc4)cc3)nn2)c1 CHEMBL4447552 IC50 0.28 nM
Cc1ccc(NC(=O)c2cc(-n3ccnc3C)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3976004 IC50 0.3 nM
Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3950106 IC50 0.3 nM
Cc1ccc(NC(=O)c2cc(C(C)(C)C)cc(C(C)(C)O)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3967492 IC50 0.3 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C#N)cc(C(C)(C)C)c1 CHEMBL3937186 IC50 0.3 nM
COc1ccc(-c2ccc(Cn3cc(-c4ccc(C(F)(F)F)cc4)nn3)cc2)cn1 CHEMBL4528844 IC50 0.3 nM
COc1ccc(-c2ccc(Cn3cc(-c4cccc(Cl)c4)nn3)cc2)cn1 CHEMBL4452256 IC50 0.36 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 IC50 0.39 nM
Cc1ccc(NC(=O)c2cc(-n3ccnc3C)cc(C(F)(F)F)c2)cc1-n1cc(C)n2nc(-c3cn[nH]c3)cc12 CHEMBL3978122 IC50 0.4 nM
Cc1cc(F)c(NC(=O)c2cc(C#N)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3922694 IC50 0.4 nM
Cc1cccc(-c2cn(Cc3ccc(-c4cccnc4)cc3)nn2)c1 CHEMBL4570075 IC50 0.45 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C#N)cc(S(F)(F)(F)(F)F)c1 CHEMBL3907057 IC50 0.45 nM
Cc1ccc(NC(=O)c2cc(-n3ccnc3C)cc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3959425 IC50 0.5 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C#N)nc(C(C)(C)C)c1 CHEMBL3950414 IC50 0.5 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(C(C)(C)C(F)(F)F)c1 CHEMBL3896522 IC50 0.5 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(C2(C)COC2)c1 CHEMBL3967691 IC50 0.5 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(Br)cc(C(C)(C)C)c1 CHEMBL3944654 IC50 0.6 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)cc2n1 CHEMBL4066813 IC50 0.6 nM
Cc1ccc(NC(=O)c2cc(CN3CCCC3)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3952341 IC50 0.7 nM
COc1ccc(-c2ccc(Cn3cc(-c4cccc(N)c4)nn3)cc2)cn1 CHEMBL4441465 IC50 0.73 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(Cl)nc(C(C)(C)C)c1 CHEMBL3957460 IC50 0.8 nM
Cn1cc(-c2ccc(Cn3cc(-c4cccc(NC(=O)C5CC5)c4)nn3)cc2)cn1 CHEMBL4539395 IC50 0.82 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3nc4ccc(Oc5ccnc(C(=O)NC)c5)cc4s3)cc2C(F)(F)F)CC1 CHEMBL4589373 IC50 0.82 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(C(C)(C)F)c1 CHEMBL3928950 IC50 0.9 nM
CCCn1c2ccc(NC(=O)Nc3cc(C)ccc3F)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL218252 IC50 1.0 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)n1 CHEMBL218632 IC50 1.0 nM
Cc1ccc(C(=O)Nc2cc(CCCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncccc1-c1ccncn1 CHEMBL221484 IC50 1.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(N)ncc2c1 CHEMBL385937 IC50 1.0 nM
CNc1cc(-c2cccnc2Oc2cc(NC(=O)c3cccc(C(C)C)c3)ccc2C)ccn1 CHEMBL245947 IC50 1.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(C(C)C)c3)ccc2C)n1 CHEMBL245746 IC50 1.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(C(=O)Nc3cccc(C(C)C)c3)ccc2C)n1 CHEMBL245744 IC50 1.0 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3cccc(C)c3)c2cc1OC CHEMBL270057 IC50 1.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c3ccccc23)n1 CHEMBL465793 IC50 1.0 nM
CCN1CCC(CNc2nccc(-c3cccnc3Oc3ccc(Nc4nc5ccccc5[nH]4)c4ccccc34)n2)CC1 CHEMBL1084451 IC50 1.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 IC50 1.1 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(Cl)c(Cl)c4)cc3)cc2n1 CHEMBL4085653 IC50 1.14 nM
Cc1ccc(NC(=O)c2cc(C#N)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3937870 IC50 1.2 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(SC(F)(F)F)c1 CHEMBL3913891 IC50 1.2 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(F)(F)F)c1 CHEMBL3931577 IC50 1.4 nM
COC(=O)Nc1cn2cc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)ccc2n1 CHEMBL243915 IC50 1.5 nM
Cc1ccc(NC(=O)c2cc(N(C)CCCN(C)C)cc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3974502 IC50 1.5 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)ccn1 CHEMBL1946170 IC50 1.5 nM
Cn1cc(-c2ccc(Cn3cc(-c4cccc(C(F)(F)F)c4)nn3)cc2)cn1 CHEMBL4476000 IC50 1.79 nM
CNc1ncc2cc(-c3cc(C(=O)Nc4cccc(C(F)(F)F)c4)ccc3C)ccc2n1 CHEMBL212964 IC50 1.8 nM
Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 CHEMBL3906358 IC50 1.9 nM
Nc1n[nH]c2cccc(-c3cccc(NC(=O)C4(C(=O)Nc5cc(Br)cc(C(F)(F)F)c5)CC4)c3)c12 CHEMBL4085495 IC50 1.95 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)cc1 CHEMBL194911 pIC50 1.995 nM
CCCn1c2ccc(NC(=O)N(C)c3ccccc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219293 IC50 2.0 nM
CCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL218201 IC50 2.0 nM
CCCn1c2ccc(NC(=O)Nc3ccccc3F)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL424910 IC50 2.0 nM
CCCn1c2ccc(NC(=O)Nc3cccc(F)c3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL426528 IC50 2.0 nM
CCCn1c2ccc(NC(=O)Nc3ccc(F)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL374745 IC50 2.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1cnc2[nH]cnc2c1 CHEMBL375840 IC50 2.0 nM
CNc1nccc(-c2cccnc2Oc2cc(NC(=O)c3cccc(C(C)C)c3)ccc2C)n1 CHEMBL394693 IC50 2.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3c(F)cccc3C(F)(F)F)cc2)cc1 CHEMBL401860 IC50 2.0 nM
CNc1nccc(-c2cccnc2Oc2c(C)cc(Nc3nc4ccccc4[nH]3)c3ccccc23)n1 CHEMBL458023 IC50 2.0 nM
CN1CCCC1CCNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c3ccccc23)n1 CHEMBL1084452 IC50 2.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)c12 CHEMBL4160854 IC50 2.13 nM
CNC(=O)c1ncc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(CCO)CC4)c(C(F)(F)F)c3)ccc2C)n1C CHEMBL1784637 IC50 2.2 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(Br)cc(C(F)(F)F)c4)cc3)cc2n1 CHEMBL4069517 IC50 2.47 nM
CC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL243916 IC50 2.6 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)cc2[nH]1 CHEMBL244079 IC50 2.6 nM
Cn1cc(-c2ccc(Cn3cc(-c4ccccc4F)nn3)cc2)cn1 CHEMBL4469077 IC50 2.69 nM
COCCOCC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL244106 IC50 2.8 nM
CC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)nc3)cc2[nH]1 CHEMBL243911 IC50 2.9 nM
CCCn1c2ccc(NC(=O)Nc3ccc(C)cc3)cc2c2c3c(c4c(c21)CC(C=N)=CC4)C(=O)NC3 CHEMBL387174 IC50 3.0 nM
CCCn1c2ccc(NC(=O)Nc3ccc(SC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219332 IC50 3.0 nM
COc1ccc(NC(=O)Nc2ccc3c(c2)c2c4c(c5c(c2n3CC(C)C)CCc2nn(C)cc2-5)C(=O)NC4)cc1 CHEMBL218816 IC50 3.0 nM
CCCn1c2ccc(NC(=O)Nc3ccccc3Cl)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219253 IC50 3.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1cnc(N)nc1 CHEMBL427998 IC50 3.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1ccc(N)nc1 CHEMBL220874 IC50 3.0 nM
CNc1cc(-c2cccnc2Oc2cc(C(=O)Nc3cccc(C(C)C)c3)ccc2C)ccn1 CHEMBL245745 IC50 3.0 nM
CCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1084061 IC50 3.0 nM
CC(C)Cn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1084337 IC50 3.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(F)(F)C(F)F)c1 CHEMBL3891004 IC50 3.2 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Cl)c(Cl)c5)CC4)cc3)c12 CHEMBL4083001 IC50 3.49 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)cn1 CHEMBL4169668 IC50 3.59 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1ncccc1-c1ccncn1 CHEMBL385956 IC50 3.6 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2o1 CHEMBL243914 IC50 3.7 nM
Cc1ccc(NC(=O)c2cc(C(F)(F)F)cc(S(N)(=O)=O)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3937098 IC50 3.9 nM
COc1cccc(NC(=O)Nc2ccc3c(c2)c2c4c(c5c(c2n3CC(C)C)CCc2nn(C)cc2-5)C(=O)NC4)c1 CHEMBL218817 IC50 4.0 nM
CCCn1c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL437876 IC50 4.0 nM
CCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL424757 IC50 4.0 nM
CCCn1c2ccc(NC(=O)Nc3ccccc3Br)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL375570 IC50 4.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N(C)CCCN(C)C)c2)n1 CHEMBL218646 IC50 4.0 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C4CCCCC4)ccc3OC)ccc2C)n1 CHEMBL220550 IC50 4.0 nM
CNc1cc(-c2cccnc2Oc2cccc(NC(=O)c3cccc(C(C)C)c3)c2)ccn1 CHEMBL246150 IC50 4.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(C(C)C)c3)ccc2F)n1 CHEMBL394694 IC50 4.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2C)n1 CHEMBL468612 IC50 4.0 nM
CCCn1c2ccc(Nc3ncc(CC)cn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010869 IC50 4.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(C)C)c1 CHEMBL3942395 IC50 4.6 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4cc(OC(F)(F)F)ccc4Br)cc3)c12 CHEMBL4168788 IC50 4.85 nM
CN1CCN(CC(=O)Nc2nc3ccc(Oc4ccc(NC(=O)Nc5cc(C(F)(F)F)ccc5F)cc4)cc3[nH]2)CC1 CHEMBL389333 IC50 4.9 nM
CCCn1c2ccc(NC(=O)Nc3ccccc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL216891 IC50 5.0 nM
CCCn1c2ccc(NC(=O)Oc3ccc(OC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL218557 IC50 5.0 nM
CN(C)[C@H]1CCCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1 CHEMBL386637 IC50 5.0 nM
Cc1ccsc1C(=O)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL401881 IC50 5.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)Nc3ccccc3)c3ccccc23)n1 CHEMBL457099 IC50 5.0 nM
C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL601719 IC50 5.0 nM
Cc1ccc(NC(=O)c2cc(-n3ccnc3C)cc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 CHEMBL3943444 IC50 5.0 nM
O=C(Nc1ccc(Oc2ccc3[nH]c(NC(=O)c4ccco4)nc3c2)cc1)Nc1cc(C(F)(F)F)ccc1F CHEMBL244297 IC50 5.2 nM
Fc1ccccc1-c1cn(Cc2ccc(-c3cncnc3)cc2)nn1 CHEMBL4459732 IC50 5.45 nM
Fc1ccccc1-c1cn(Cc2ccc(-c3cn[nH]c3)cc2)nn1 CHEMBL4437530 IC50 5.46 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)nc2[nH]1 CHEMBL244101 IC50 5.6 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)cn1 CHEMBL4171543 IC50 5.63 nM
CNc1cc(-c2cccnc2Nc2c(C)ccc3c(Nc4ccc5sc(C)nc5c4)nccc23)ncn1 CHEMBL570573 IC50 5.8 nM
CCCn1c2ccc(NC(=O)Nc3ccc(N(C)C)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL375311 IC50 6.0 nM
CCCn1c2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219581 IC50 6.0 nM
CNc1ncnc(-c2cccnc2Oc2ccc(F)c(C(=O)Nc3cc(C(C)C)ccc3N(C)CCCN(C)C)c2)n1 CHEMBL266311 IC50 6.0 nM
CNc1cc(-c2cccnc2Oc2ccc(Cl)c(NC(=O)c3cccc(C(C)C)c3)c2)ccn1 CHEMBL246151 IC50 6.0 nM
CNc1ncnc(-c2cccnc2Oc2cccc(NC(=O)c3cccc(C(C)C)c3)c2)n1 CHEMBL245948 IC50 6.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(Br)ccc5OC(F)(F)F)CC4)cc3)c12 CHEMBL4092519 IC50 6.05 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4Cl)cc3)cc2[nH]1 CHEMBL244286 IC50 6.3 nM
Nc1n[nH]c2cccc(-c3cccc(NC(=O)C4(C(=O)Nc5cc(Br)ccc5OC(F)(F)F)CC4)c3)c12 CHEMBL4063920 IC50 6.34 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2s1 CHEMBL244482 IC50 6.5 nM
Cc1ccc(NC(=O)c2cc(CN3CCCC3)cc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 CHEMBL3931060 IC50 6.7 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc6c(c5)OCO6)CC4)cc3)c12 CHEMBL4101918 IC50 6.72 nM
COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)ccc2[nH]1 CHEMBL396056 IC50 6.9 nM
COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cc(F)ccc4C(F)(F)F)cc3)ccc2[nH]1 CHEMBL5401507 IC50 6.9 nM
CCCCn1c2ccc(NC(=O)Nc3ccc(OC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL374736 IC50 7.0 nM
CCCOC(=O)Nc1ccc2c(c1)c1c3c(c4c(c1n2CCC)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL373575 IC50 7.0 nM
CNc1cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)cc(C(C)(C)C)n1 CHEMBL3915487 IC50 7.9 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccccc3Cl)cc2)cn1 CHEMBL4161735 IC50 7.97 nM
COc1ccccc1NC(=O)Nc1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL265600 IC50 8.0 nM
CN(C)CCCN(C)c1ccc(C(F)(F)F)cc1NC(=O)c1cc(C#Cc2cnc(N)nc2)ccc1F CHEMBL373621 IC50 8.0 nM
COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)ccc2[nH]1 CHEMBL243908 IC50 8.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(OC(F)(F)F)c3)ccc2C)n1 CHEMBL246152 IC50 8.0 nM
O=C(Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1)C1CC1 CHEMBL3545365 IC50 8.0 nM
C#Cc1cccc(Nc2nccc3c(Nc4ncccc4-c4cc(NC)ncn4)c(C)ccc23)c1 CHEMBL571278 IC50 8.1 nM
COc1ccc(C)cc1NC(=O)Nc1cccc(C(=O)c2cn(C3CCCC3)c3ncnc(N)c23)c1 CHEMBL2387001 IC50 8.8 nM
CNc1cc(-c2cccnc2Oc2cc(NC(=O)c3cccc(OC(F)(F)C(F)F)c3)ccc2C)ccn1 CHEMBL397090 IC50 9.0 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3cccc(Cl)c3)c2cc1OC CHEMBL272878 IC50 9.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(F)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593987 IC50 9.0 nM
C=CCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1082755 IC50 9.0 nM
Cn1cc(-c2ccc(Cn3cc(-c4ccc(C(F)(F)F)cc4)nn3)cc2)cn1 CHEMBL4525897 IC50 9.11 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(C(C)C)c3)cc2)cn1 CHEMBL4175773 IC50 9.19 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(OC(F)(F)F)cc4Br)cc3)cc2n1 CHEMBL4060841 IC50 9.68 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)cn1 CHEMBL4176454 IC50 9.77 nM
CC(C)Cn1c2ccc(NC(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL426703 IC50 10.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)n1 CHEMBL426211 IC50 10.0 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCOCC3)ccc2C)n1 CHEMBL219158 IC50 10.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1cnc2ccccc2c1 CHEMBL219584 IC50 10.0 nM
COC(=O)Nc1nc2ccc(Sc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL243912 IC50 10.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(SC(F)(F)F)c4)cc3)cc2[nH]1 CHEMBL244095 IC50 10.0 nM
C/C(=N\OCC(C)C)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL258433 IC50 10.0 nM
CC(C)n1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1084062 IC50 10.0 nM
CCCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1082829 IC50 10.0 nM
CCc1cnc(Nc2ccc3c(c2)c2c4c(c5c(c2n3CC(C)C)CCc2nn(C)cc2-5)C(=O)NC4)nc1 CHEMBL2010873 IC50 10.0 nM
Cc1ccc(NC(=O)c2ccc(C)c(C(F)(F)F)c2)cc1C#Cc1nn([C@H]2CC[C@H](O)CC2)c2ncnc(N)c12 CHEMBL4798527 IC50 10.0 nM
NC(=O)c1c(OCc2c(F)cc(Br)cc2F)nsc1NC(=O)NCCCCN1CCCC1 CHEMBL253969 IC50 10.1 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL273564 Log IC50 10.23 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccccc3Cl)cc2)n1 CHEMBL4172089 IC50 10.29 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1 CHEMBL103667 Kd 11.0 nM
CCCn1c2ccc(NC(=O)OC(C)C)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219492 IC50 11.0 nM
CCCn1c2ccc(NC(=O)Oc3ccc(F)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL265284 IC50 11.0 nM
Nc1ncc(C#Cc2cccc(C(=O)Nc3cccc(C(F)(F)F)c3)c2)cn1 CHEMBL375819 IC50 11.0 nM
COC(=O)Nc1nc2ccc(C(=O)c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL244100 IC50 11.0 nM
CCCn1c2ccc(NC(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL220406 IC50 12.0 nM
COc1ccc2cc(-c3c(-c4ccncc4)nc(-c4ccc([S+](C)[O-])cc4C)n3C)ccc2c1 CHEMBL237570 IC50 12.0 nM
COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 CHEMBL509032 IC50 12.0 nM
Cc1ccc(F)c(NC(=O)Nc2cccc(C(=O)c3cn(C4CCCC4)c4ncnc(N)c34)c2)c1 CHEMBL2387000 IC50 12.0 nM
O=C(Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1)Nc1cccc(C(F)(F)F)c1 CHEMBL4167030 IC50 12.81 nM
CNc1ncnc(-c2cccnc2Oc2ccc(F)c(C(=O)Nc3cc(C4CC4)ccc3N(C)CCCN(C)C)c2)n1 CHEMBL375793 IC50 13.0 nM
Nc1ncc(C#Cc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCC[C@H](N)C3)c2)cn1 CHEMBL374079 IC50 13.0 nM
CN1CCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)CC1 CHEMBL376475 IC50 13.0 nM
O=C(Nc1ccc(Oc2ccc3[nH]c(NC(=O)c4ccccc4)nc3c2)cc1)Nc1cc(C(F)(F)F)ccc1F CHEMBL243917 IC50 13.0 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cccc(C(C)C)c3)ccc2C)n1 CHEMBL394692 IC50 13.0 nM
CC(C)Cn1c2ccc(C(=O)c3sccc3Cl)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL269924 IC50 13.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(Br)cc(C(F)(F)F)c5)CC4)cc3)c12 CHEMBL4086694 IC50 13.22 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL247228 Log IC50 13.49 nM
Cc1cccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)c1 CHEMBL4553163 IC50 13.71 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)n1 CHEMBL4165320 IC50 13.75 nM
CN[C@H]1CCCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1 CHEMBL220532 IC50 14.0 nM
CCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1083757 IC50 14.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(C)c(Cl)c3)cc2)cn1 CHEMBL4168590 IC50 14.2 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(C)c(Cl)c3)cc2)n1 CHEMBL4160813 IC50 14.2 nM
COc1cc2nccc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3)c2cc1OC CHEMBL2105717 IC50 14.3 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(F)c5)CC4)cc3)cc2n1 CHEMBL4166401 IC50 14.49 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(OC(F)(F)F)ccc5Br)CC4)cc3)cc2n1 CHEMBL4162947 IC50 14.65 nM
CC(C)Cn1c2ccc(C(=O)c3sccc3Br)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL403158 IC50 15.0 nM
Cc1ccc(NC(=O)c2cc(C#N)cc(OC(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3963905 IC50 15.0 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(Br)cc4OC(F)(F)F)cc3)cc2n1 CHEMBL4089043 IC50 15.68 nM
O=C(Nc1ccc(Oc2ccc3nc(NC(=O)c4cccnc4)[nH]c3c2)cc1)Nc1cc(C(F)(F)F)ccc1F CHEMBL244486 IC50 16.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(OC(F)(F)C(F)F)c3)ccc2C)n1 CHEMBL246356 IC50 16.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4o3)c3ccccc23)n1 CHEMBL456463 IC50 16.0 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(CCCO)c13)CNC2=O CHEMBL1085540 IC50 16.0 nM
O=C(Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1)Nc1ccc(F)c(F)c1 CHEMBL4174261 IC50 16.55 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(Cl)c(Cl)c4)cc3)c12 CHEMBL4175943 IC50 16.7 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccccc3F)cc2)n1 CHEMBL4174374 IC50 16.77 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cc1 CHEMBL381207 pIC50 16.98 nM
Nc1ncc(C#Cc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)c2)cn1 CHEMBL374985 IC50 17.0 nM
Nc1ncc(-c2cccc(S(N)(=O)=O)c2)c2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL241682 IC50 17.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(-n4cccc4)c3)ccc2C)n1 CHEMBL246355 IC50 17.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1ncccc1-c1ccncn1 CHEMBL245549 IC50 17.0 nM
CCOCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1082756 IC50 17.0 nM
CCCn1c2ccc(NC(=O)OCC)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219493 IC50 18.0 nM
CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1 CHEMBL243907 IC50 18.0 nM
CC(C)Cn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1c-4cnn1C)C(=O)NC3 CHEMBL1085294 IC50 18.0 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL262433 IC50 19.0 nM
CCCn1c2ccc(NC(=O)Nc3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219555 IC50 19.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 19.0 nM
CC(C)(O)COc1ccc2c(Oc3ccc(Nc4nccc5[nH]cc(-c6ccccc6)c(=O)c45)cc3F)ccnc2c1 CHEMBL4747900 IC50 19.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(Cl)cc4Cl)cc3)c12 CHEMBL4175949 IC50 19.8 nM
CC(C)Cn1c2ccc(NC(=O)c3ccco3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219080 IC50 20.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cn3)cc2[nH]1 CHEMBL243910 IC50 20.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)n1 CHEMBL397089 IC50 20.0 nM
CC(C)Cn1c2ccc(C(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL444105 IC50 20.0 nM
Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c21 CHEMBL1254007 IC50 20.0 nM
COc1ccc(C#Cc2cnc(N)nc2)cc1C(=O)Nc1cc(C(F)(F)F)ccc1N1CCCCC1 CHEMBL375617 IC50 21.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(N)ncc2c1 CHEMBL429582 IC50 21.0 nM
CC(C)CCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1084338 IC50 21.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(C(F)(F)F)cc(C(F)(F)F)c5)CC4)cc3)cc2n1 CHEMBL4174711 IC50 21.2 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)cc2)cn1 CHEMBL4167913 IC50 21.27 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(Cl)cc3Cl)cc2)n1 CHEMBL4160431 IC50 21.52 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2)cc1 CHEMBL372617 pIC50 21.88 nM
Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL214258 IC50 22.0 nM
CNc1ncnc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C4CCCCC4)ccc3OC)ccc2C)n1 CHEMBL220640 IC50 22.0 nM
COc1ccc2cc(-c3nc(-c4ccc([S@@+](C)[O-])cc4C)[nH]c3-c3ccncc3)ccc2c1 CHEMBL2096892 IC50 22.0 nM
CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010872 IC50 22.0 nM
COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(/C=C/c4ccc(CN5C[C@@H](C)O[C@@H](C)C5)cc4)n[nH]c3c1)C(=O)N2 CHEMBL3408947 IC50 22.0 nM
C#Cc1cccc(NC(=O)C2(C(=O)Nc3ccc(-c4ccc5c(=O)nc[nH]c5c4)cc3)CCC2)c1 CHEMBL4167570 IC50 22.15 nM
C/C(=N\OCC(C)C)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL258222 IC50 23.0 nM
CCO/N=C(\C)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL404718 IC50 23.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)cc2C)n1 CHEMBL516817 IC50 23.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(F)c5)CC4)cc3)c12 CHEMBL4100979 IC50 23.78 nM
CC(C)n1c2ccc(C(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL402182 IC50 24.0 nM
CNc1cc(-c2cccnc2Nc2c(C)ccc3c(Nc4ccc(Cl)cc4)nccc23)ncn1 CHEMBL565885 IC50 24.0 nM
CCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1c-4cnn1C)C(=O)NC3 CHEMBL1083042 IC50 24.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OCC(F)(F)F)c1 CHEMBL3919064 IC50 24.0 nM
c1ccc(-c2cn(Cc3ccc(-c4cccnc4)cc3)nn2)cc1 CHEMBL4556134 IC50 24.19 nM
O=C(Nc1cccc(Cl)c1)Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1 CHEMBL4163581 IC50 24.75 nM
CCO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL428433 IC50 25.0 nM
Cc1ccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)cc1 CHEMBL4452405 IC50 25.74 nM
CCO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2C(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL401896 IC50 26.0 nM
CCCn1c2ccc(C(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL255959 IC50 26.0 nM
COc1cc2c(Oc3ccc(-c4cnc(Nc5ccc(F)cc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL453737 IC50 26.0 nM
Cc1ccc(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(C#N)cc(C(C)(C)C)c1 CHEMBL3929545 IC50 26.0 nM
Cn1cc(-c2ccc(F)cc2)c(=O)c2c(Nc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)c(F)c3)nccc21 CHEMBL4584949 IC50 26.3 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccc(C(F)(F)F)cc4[nH]3)c3ccccc23)n1 CHEMBL463323 IC50 27.0 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(CCO)c13)CNC2=O CHEMBL1085293 IC50 27.0 nM
CCCn1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010871 IC50 27.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3ccccc3)cc2)cc1 CHEMBL194149 IC50 28.0 nM
Nc1ncnc2snc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c12 CHEMBL213504 IC50 28.0 nM
COC(=O)Nc1nc2cc(Oc3cccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c3)ccc2[nH]1 CHEMBL244289 IC50 28.0 nM
C/C(=N\OC(C)C)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL258000 IC50 28.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=S)Nc4ccc(F)c(F)c4)cc3)c12 CHEMBL4167759 IC50 28.32 nM
CCCn1c2ccc(NC(=O)c3ccco3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL425109 IC50 29.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3F)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL594228 IC50 29.0 nM
Cc1ccc(NC(=O)c2cc(C#N)cc(C3(O)CCC3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3904599 IC50 29.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 29.9 nM
CNc1ncnc(-c2cccnc2Oc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N(C)CCCN(C)C)c2)n1 CHEMBL373882 IC50 30.0 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2Cl)n1 CHEMBL374997 IC50 30.0 nM
Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2N2CCCCC2)cc1C#Cc1cnc(N)nc1 CHEMBL219103 IC50 30.0 nM
CO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL258015 IC50 30.0 nM
CCCn1c2ccc(/C(C)=N/OC)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL258014 IC50 30.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)n1 CHEMBL4175530 IC50 31.15 nM
COc1ccc(C(F)(F)F)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1079846 IC50 33.0 nM
Cc1ccc(NC(=O)c2cc(N3CCN(C)CC3)cc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3930956 IC50 35.0 nM
CCCn1c2ccc(N)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL373397 IC50 36.0 nM
COc1ccc2cc(-c3nc(-c4ccc([S+](C)[O-])cc4C)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236716 IC50 36.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(Cl)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593274 IC50 37.0 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(C(F)(F)F)ccc1F CHEMBL1079850 IC50 37.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3cccc(F)c3)cc2)n1 CHEMBL4166465 IC50 37.24 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3C)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595406 IC50 38.0 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2C)n1 CHEMBL218576 IC50 39.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)c2)n1 CHEMBL219583 IC50 40.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)cc2[nH]1 CHEMBL396283 IC50 40.0 nM
COc1ccc2cc(-c3nc(-c4ccc(S(C)(=O)=O)cc4C)[nH]c3-c3ccncc3)ccc2c1 CHEMBL391891 IC50 40.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2n1C CHEMBL244291 IC50 41.0 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(C)c13)CNC2=O CHEMBL1082826 IC50 41.0 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(C4CCCC4)c13)CNC2=O CHEMBL1083454 IC50 41.0 nM
Cc1ccc(NC(=O)c2ccnc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3906508 IC50 41.0 nM
O=C(Nc1ccc(-c2ccc3c(=O)nc[nH]c3c2)cc1)C1(C(=O)Nc2cccc(F)c2)CCC1 CHEMBL4164800 IC50 42.15 nM
COc1ccc(C(F)(F)F)cc1NC(=O)c1ccc(C)c(Nc2ncccc2-c2ccncn2)c1 CHEMBL219996 IC50 43.0 nM
Cc1csc(C(=O)c2ccc3c(c2)c2c4c(c5c(c2n3CC(C)C)CCc2nn(C)cc2-5)C(=O)NC4)c1 CHEMBL271861 IC50 43.0 nM
CCn1c2ccc(C(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL402531 IC50 43.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(F)F)c1 CHEMBL3927973 IC50 43.0 nM
CN(C)[C@@H]1CCCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1 CHEMBL218110 IC50 44.0 nM
C/C(=N\O)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL404322 IC50 44.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4s3)c3ccccc23)n1 CHEMBL456683 IC50 44.0 nM
COc1cc2c(Oc3ccc(-c4nc5ccccc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595143 IC50 44.0 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c1[nH]c1ccc(C4CCCCO4)cc13)CNC2=O CHEMBL1082503 IC50 44.0 nM
CCn1c2ccc(/C(C)=N/OCC(C)C)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL401897 IC50 45.0 nM
Nc1ncnc2c1c(C(=O)c1cccc(NC(=O)Nc3ccc(Cl)cc3)c1)cn2C1CCCC1 CHEMBL2386998 IC50 45.0 nM
Nc1ncc(-c2ccccc2)c2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)c12 CHEMBL241681 IC50 46.0 nM
C/C(=N\OCC(C)C)c1ccc2c(c1)c1c3c(c4c(c1n2C(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL258436 IC50 46.0 nM
Cc1cccc(-c2cn(Cc3ccc(-c4cn[nH]c4)cc3)nn2)c1 CHEMBL4472113 IC50 46.39 nM
Nc1ncc(C#Cc2ccc(F)c(C(=O)Nc3cccc(C(F)(F)F)c3)c2)cn1 CHEMBL218631 IC50 47.0 nM
Cc1ccc2c(Nc3cccc(C(F)(F)F)c3)nccc2c1Nc1ncccc1-c1ccncn1 CHEMBL571703 IC50 47.0 nM
CC(C)Cn1c2ccc(N)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL218799 IC50 48.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(C(F)(F)F)cc(C(F)(F)F)c5)CC4)cc3)c12 CHEMBL4075266 IC50 49.97 nM
COc1ccc2cc(-c3nc(-c4ccc([S+](C)[O-])cc4Cl)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236924 IC50 51.0 nM
Cc1cccc(-c2cn(Cc3ccc(-c4cnn(C)c4)cc3)nn2)c1 CHEMBL4436670 IC50 51.44 nM
c1ccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)cc1 CHEMBL4456738 IC50 51.86 nM
C/C(=N\OC(C)C)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL403823 IC50 52.0 nM
Cc1ccc(NC(=O)c2cccc(N3CCCC3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3905136 IC50 52.0 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(F)c(F)c4)cc3)cc2n1 CHEMBL4080224 IC50 52.04 nM
CNc1ncnc(-c2cccnc2Oc2ccc(F)c(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)c2)n1 CHEMBL221087 IC50 53.0 nM
CCCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1c-4cnn1C)C(=O)NC3 CHEMBL1083386 IC50 53.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OCC(C)C)c1 CHEMBL3905415 IC50 53.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595615 IC50 54.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Cl)cc5Cl)CC4)cc3)cc2n1 CHEMBL4170879 IC50 54.9 nM
CNc1ncnc(-c2cccnc2Oc2cc(NC(=O)c3cccc(C(C)C)c3)cc(C(F)(F)F)c2)n1 CHEMBL245949 IC50 55.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(C)(C)C)c1 CHEMBL3933416 IC50 55.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cccc(SC)c4)cc3)cc2[nH]1 CHEMBL244096 IC50 56.0 nM
Cc1ccc(NC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3924803 IC50 56.0 nM
Cc1ccc(NC(=O)c2cccc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3975340 IC50 56.0 nM
Cc1nc(Nc2nc3ccc(-c4cccc(C(=O)Nc5cccc(C(F)(F)F)c5)c4)nc3s2)cc(N2CCNCC2)n1 CHEMBL2148120 Kd 57.0 nM
Cc1ccc(NC(=O)c2cc(Cl)nc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3953768 IC50 57.0 nM
Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3910445 IC50 57.0 nM
CC(C)Cn1c2ccc(C(=O)c3ccoc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL411520 IC50 58.0 nM
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCC(O)C1 CHEMBL69129 IC50 58.3 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)NC3CCCCC3)cc2)cc1 CHEMBL195567 pIC50 58.88 nM
CNc1ncnc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N(C)CCCN(C)C)ccc2C)n1 CHEMBL278965 IC50 59.0 nM
COc1ccc2cc(-c3nc(-c4ccc(S(C)(=O)=O)cc4Cl)[nH]c3-c3ccncc3)ccc2c1 CHEMBL392332 IC50 59.0 nM
CCn1cc(-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1 CHEMBL1090479 IC50 59.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)cn1 CHEMBL4173072 IC50 59.93 nM
Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL387817 IC50 60.0 nM
COC(=O)Nc1nc2ccc([S+]([O-])c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL244098 IC50 60.0 nM
COc1ccc2cc(-c3c(-c4ccncc4)nc(-c4ccc([S+](C)[O-])cc4)n3C)ccc2c1 CHEMBL399410 IC50 60.0 nM
Fc1ccccc1-c1cn(Cc2ccc(-c3cccnc3)cc2)nn1 CHEMBL4454065 IC50 61.26 nM
CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2F)n1 CHEMBL374259 IC50 62.0 nM
CNc1cc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C4CCCCC4)ccc3OC)ccc2C)ccn1 CHEMBL218040 IC50 62.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(C(C)(C)O)c1 CHEMBL3891050 IC50 62.0 nM
Nc1ncc(C#Cc2cccc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)c2)cn1 CHEMBL220482 IC50 63.0 nM
CC(C)Cn1c2ccc(C(=O)c3ccsc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL271849 IC50 63.0 nM
Cc1cc(Br)ccc1NC(=O)C1(C(=O)Nc2ccc(-c3ccc4c(=O)nc[nH]c4c3)cc2)CCC1 CHEMBL4169220 IC50 64.33 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(N2CCC(F)(F)CC2)c1 CHEMBL3979351 IC50 65.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(Br)cc(C(F)(F)F)c5)CC4)cc3)cc2n1 CHEMBL4165234 IC50 65.26 nM
C/C(=N\OC(C)C)c1ccc2c(c1)c1c3c(c4c(c1n2C(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL429138 IC50 66.0 nM
Cc1c2cc(cc1C(=O)Nc1cc(CN3CCN(C)CC3)cc(C3CC3)c1)OCCCCCCCNC(=O)c1ccc3ncc(n3n1)C#C2 CHEMBL5423601 IC50 66.27 nM
O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 CHEMBL1081198 IC50 67.0 nM
COc1cc(Nc2ncnc(-c3cccnc3Nc3ccccc3)n2)cc(OC)c1OC CHEMBL218057 IC50 68.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(C)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL596087 IC50 68.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)cc2)n1 CHEMBL4164213 IC50 68.68 nM
Cn1cnc(-c2cccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)c2)c1-c1cc2c(N)ncnc2s1 CHEMBL1080303 IC50 70.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c[n+]3[O-])cc2[nH]1 CHEMBL397757 IC50 71.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(F)ccc4F)cc3)cc2[nH]1 CHEMBL243909 IC50 71.0 nM
CO/N=C(\C)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL257789 IC50 71.0 nM
Cc1ccc(NC(=O)c2ccnc(N3CCCCC3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3981291 IC50 71.0 nM
CC(C)Cn1c2ccc(C(=O)c3ccco3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL410100 IC50 72.0 nM
COc1cc2c(Oc3ccc(-c4nc5ccccc5s4)cc3)ncnc2cc1OCCCN1CCCC1 CHEMBL595373 IC50 72.0 nM
O=C(Nc1ccc(-c2ccc3c(=O)nc[nH]c3c2)cc1)C1(C(=O)Nc2cccc(C(F)(F)F)c2)CCC1 CHEMBL4164127 IC50 73.59 nM
COc1ccc(Br)cc1NC(=O)Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1 CHEMBL1080639 IC50 75.0 nM
CCn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc21 CHEMBL4281823 IC50 75.0 nM
CC(C)n1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010870 IC50 76.0 nM
Cc1ccc(-c2cn(Cc3ccc(-c4cnn(C)c4)cc3)nn2)cc1 CHEMBL4543212 IC50 77.42 nM
COc1ccc2cc(-c3nc(-c4c(Cl)cccc4Cl)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236503 IC50 78.0 nM
CCCCCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1083144 IC50 78.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4ccc5ccccc5c4)cc3)c12 CHEMBL436806 Log IC50 81.28 nM
COc1ccc2cc(-c3nc(-c4ccccc4Br)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236300 IC50 82.0 nM
CN(C)CC(C)(C)CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c3ccccc23)n1 CHEMBL1084453 IC50 82.0 nM
CC(=O)c1ccc2c(c1)c1c3c(c4c(c1n2CC(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL401900 IC50 83.0 nM
COc1cc(Nc2ncnc(-c3cccnc3Nc3cccc(C(=O)Nc4ccc(Oc5ccccc5)cc4)c3)n2)cc(OC)c1OC CHEMBL220540 IC50 85.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1cnc2ccccc2n1 CHEMBL221019 IC50 85.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccncc4[nH]3)c3ccccc23)n1 CHEMBL1086334 IC50 86.0 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(OC(F)(F)F)ccc4Br)cc3)cc2n1 CHEMBL4088100 IC50 87.38 nM
COc1cc2c(Oc3ccc(-c4nc5ccccc5s4)cc3F)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL604483 IC50 88.0 nM
CCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1c-4cnn1C)C(=O)NC3 CHEMBL1082438 IC50 88.0 nM
O=C(Nc1ccc(-c2ccc3c(=O)nc[nH]c3c2)cc1)C1(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)CCC1 CHEMBL4159645 IC50 88.64 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(F)c3)cc2)cn1 CHEMBL4161345 IC50 90.86 nM
COC(=O)Nc1nc2ncc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL387604 IC50 91.0 nM
CCO/N=C(/c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4)C(C)C CHEMBL257794 IC50 92.0 nM
C/C(=N\OC(C)(C)C)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL255281 IC50 93.0 nM
Cc1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(N)ncc2c1 CHEMBL409914 IC50 93.0 nM
COc1ccc2cc(-c3nc(-c4ccc([S@+](C)[O-])cc4C)[nH]c3-c3ccncc3)ccc2c1 CHEMBL2448122 IC50 95.0 nM
CO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2C(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL401876 IC50 97.0 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3cccc(C(C)C)c3)cc2)n1 CHEMBL4167663 IC50 97.74 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3ccc(OC(F)(F)F)cc3)cc2)n1 CHEMBL4171035 IC50 98.12 nM
CNc1nccc(-c2cccnc2Oc2cccc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)c2)n1 CHEMBL221119 IC50 99.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc1 CHEMBL370325 IC50 100.0 nM
COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)c2cc1OC CHEMBL2031893 IC50 100.0 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(C4CCCCC4)c13)CNC2=O CHEMBL1085291 IC50 102.0 nM
COc1ccc(C(F)(F)F)cc1NC(=O)c1ccc(C)c(Oc2ncccc2-c2ccncn2)c1 CHEMBL220549 IC50 103.0 nM
CC(C)n1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1c-4cnn1C)C(=O)NC3 CHEMBL1083350 IC50 103.0 nM
Cc1ccc(NC(=O)c2cccc(C(C)(C)C)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 CHEMBL3967647 IC50 105.0 nM
C=CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3ccc(F)cc3)cc2)cn1 CHEMBL4171943 IC50 105.07 nM
CNc1ncnc(-c2cc(C)cnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2C)n1 CHEMBL219218 IC50 108.0 nM
CCCCn1c2ccc(/C(C)=N/OC)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL403606 IC50 108.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371329 pIC50 109.65 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CCCO)sc4ncnc(N)c34)cc2)c1 CHEMBL198297 pIC50 109.65 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3ccc(Cl)cc3)c2cc1OC CHEMBL270548 IC50 110.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4cccc(C)c4[nH]3)c3ccccc23)n1 CHEMBL457100 IC50 110.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(OC)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593860 IC50 110.0 nM
COc1ccc2cc(-c3c(-c4ccncc4)nc(-c4ccc(S(C)(=O)=O)cc4C)n3C)ccc2c1 CHEMBL237571 IC50 114.0 nM
Cc1ccc(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(Br)cc(C(C)(C)C)c1 CHEMBL3920770 IC50 115.0 nM
Cc1ccc(NC(=O)C2(C(=O)Nc3ccc(-c4ccc5c(=O)nc[nH]c5c4)cc3)CCC2)cc1Cl CHEMBL4161287 IC50 115.15 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CCC(N)=O)sc4ncnc(N)c34)cc2)c1 CHEMBL197635 IC50 120.0 nM
COC(=O)Nc1nc2ccc(S(=O)(=O)c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 CHEMBL244099 IC50 120.0 nM
Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc1ncccc1-c1ncnc2[nH]cnc12 CHEMBL3215582 IC50 120.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)c(O)c3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL606466 IC50 120.0 nM
COc1cc2nccc(Oc3ccc4c(NC(=O)c5cccc(C(F)(F)F)c5)nn(C)c4c3)c2cc1OC CHEMBL462168 IC50 121.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1 CHEMBL408070 IC50 123.0 nM
Cc1ccc(NC(=O)c2cccc(OC(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3910280 IC50 125.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(Br)c2)cc1 CHEMBL195955 pIC50 128.82 nM
NCc1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1C1CCCC1 CHEMBL68082 IC50 130.0 nM
CN1CCN(CCNc2nc3ccc(Oc4ccc(NC(=O)Nc5cc(C(F)(F)F)ccc5F)cc4)cc3[nH]2)CC1 CHEMBL390696 IC50 130.0 nM
Cc1ccc(NC(=O)c2cc(C#N)cc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3956530 IC50 130.0 nM
O=C(Nc1ccc(-c2ccc3c(=O)nc[nH]c3c2)cc1)C1(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC1 CHEMBL4174775 IC50 133.47 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Br)cc5OC(F)(F)F)CC4)cc3)c12 CHEMBL4104599 IC50 134.12 nM
C=CC(=O)Nc1cccc(-c2ccc(NC(=O)Nc3c(C)cccc3C)cc2)n1 CHEMBL4170942 IC50 134.67 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c1[nH]c1ccc(C(=O)c4cccs4)cc13)CNC2=O CHEMBL428876 IC50 136.0 nM
CCCn1c2ccccc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL271042 IC50 136.0 nM
COc1cc(-c2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NS(=O)(=O)c1ccccc1 CHEMBL402673 IC50 137.0 nM
COc1cc(-c2cn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NS(=O)(=O)c1ccccc1 CHEMBL2387003 IC50 137.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CCC(=O)N(C)C)sc4ncnc(N)c34)cc2)c1 CHEMBL382112 IC50 140.0 nM
CN(C)[C@H]1CCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1 CHEMBL220750 IC50 140.0 nM
COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1 CHEMBL491473 Kd 140.0 nM
CCN(CC)CCn1c2ccc(C3CCCCO3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL1085541 IC50 142.0 nM
CO/N=C/c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL257787 IC50 148.0 nM
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CC(O)C(O)C1 CHEMBL69827 IC50 150.0 nM
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Oc1ncccc1-c1ccncn1 CHEMBL218425 IC50 153.0 nM
COc1ccc2cc(-c3nc(-c4ccccc4Cl)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236299 IC50 157.0 nM
CC(C)n1cc(-c2ccc(Oc3ccccc3CO)cc2)c2c(N)ncnc21 CHEMBL71541 IC50 162.0 nM
Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(Cl)cc4Cl)cc3)cc2n1 CHEMBL4104466 IC50 164.35 nM
CC(C)n1c2ccc(Nc3cccnn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL2010877 IC50 166.0 nM
Cc1cc(C)cc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371206 pIC50 169.82 nM
Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 CHEMBL223360 IC50 170.0 nM
CC(C)N(Cc1ccccc1)c1nc(O)nc(Nc2ccc3ncsc3c2)n1 CHEMBL176019 IC50 180.0 nM
Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2N2CCCCC2)cc1Nc1ncccc1-c1ccncn1 CHEMBL373682 IC50 181.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cccc5ccccc45)cc3)c12 CHEMBL247252 Log IC50 181.97 nM
CS(=O)(=O)Nc1cccc(-c2oc3ncnc(N)c3c2-c2ccc(-c3ccccc3)cc2)c1 CHEMBL196841 IC50 190.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CCN(C)C)sc4ncnc(N)c34)cc2)c1 CHEMBL196636 IC50 190.0 nM
COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3cc(OC)c(OCCCN4CCN(C)CC4)c(OC)c3)n2)c(OC)c1 CHEMBL386760 IC50 200.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1N1Cc2cnc(N)nc2N(C)C1=O CHEMBL459850 EC50 200.0 nM
CNc1ncc2cc(-c3c(C)ccc4c(Nc5cc(C(C)(C)C)nn5C)nccc34)ccc2n1 CHEMBL569882 IC50 200.0 nM
Nc1nc(Nc2ccc([C@H]3CC[C@H](N4CCOCC4)CC3)cc2)nn1-c1ccccn1 CHEMBL1835870 Ki 200.0 nM
c1ccc(-c2c(-c3ccc(OCCN4CCCC4)cc3)[nH]c3ncnc(NCC4SCCS4)c23)cc1 CHEMBL2087875 Ki 200.0 nM
CN1CCN([C@H]2CC[C@H](n3nc(-c4ccc(NCc5cc6ccccc6[nH]5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL45683 IC50 203.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4Cl)cc3)c12 CHEMBL437369 Log IC50 204.17 nM
Cc1cccc(Cn2nc(C)c3c(NC(=O)c4csc5c(N)ncnc45)cccc32)n1 CHEMBL4483816 IC50 208.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 CHEMBL382517 pIC50 208.93 nM
Nc1cccc(-c2cn(Cc3ccc(-c4cncnc4)cc3)nn2)c1 CHEMBL4448354 IC50 210.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)NC(C)(C)C)c3ccccc23)n1 CHEMBL1084633 IC50 215.0 nM
Cc1cn(-c2cc(NC(=O)c3cc4cc(c3C)C#Cc3cnc5ccc(nn35)N(C)CCNC(=O)CCCCO4)cc(C(F)(F)F)c2)cn1 CHEMBL5195469 IC50 216.7 nM
COCCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 CHEMBL198155 pIC50 218.78 nM
Cc1ccc2cc(-c3nc(-c4ccc([S+](C)[O-])cc4)[nH]c3-c3ccncc3)ccc2c1 CHEMBL400840 IC50 219.0 nM
CN(C)[C@@H]1CCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)C1 CHEMBL221544 IC50 220.0 nM
COc1cc2c(Oc3ccc(-c4cnc(Nc5ccc(F)cc5)n(C)c4=O)nc3)ccnc2cc1OCCCN1CCOCC1 CHEMBL447602 IC50 221.0 nM
COc1ccc(F)c(NC(=O)Nc2ccc(-c3coc4ncnc(N)c34)cc2)c1 CHEMBL391184 Log IC50 223.87 nM
CCCCn1c2ccc(N)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL219543 IC50 230.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3O)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL595142 IC50 230.0 nM
Cc1cc(C)cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 CHEMBL3921135 IC50 230.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccc(F)cc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL604992 IC50 235.0 nM
CC(C)n1cc(-c2ccc(Oc3ccccc3C#N)cc2)c2c(N)ncnc21 CHEMBL71722 IC50 239.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4n3C)c3ccccc23)n1 CHEMBL457984 IC50 240.0 nM
CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1c-4cnn1C)C(=O)NC3 CHEMBL2011061 IC50 241.0 nM
Nc1ncnc2c1c(-c1nc3ccc(NC(=O)Nc4c(F)cccc4F)cc3[nH]1)cn2C1CCCC1 CHEMBL2387005 IC50 241.0 nM
O=C(Nc1cccc(-c2ccc3c(=O)[nH]cnc3c2)c1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL4159125 IC50 245.28 nM
CC(C)n1cc(-c2ccc(Oc3ccc(CO)cc3)cc2)c2c(N)ncnc21 CHEMBL70034 IC50 246.0 nM
CCNC(=O)Nc1ccc(Oc2ncccc2-c2ccnc(NC)n2)c2ccccc12 CHEMBL1084634 IC50 248.0 nM
COc1ccc(-c2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)c2c(N)noc12 CHEMBL270084 IC50 249.0 nM
CN1CCN([C@H]2CC[C@H](n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL45177 IC50 250.0 nM
CN1CCN([C@H]2CC[C@@H](n3cc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL47203 IC50 250.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(Cc4cccnc4)sc4ncnc(N)c34)cc2)c1 CHEMBL371379 IC50 250.0 nM
COc1ccc2cc(-c3nc(-c4ccc([S+](C)[O-])cc4)[nH]c3-c3ccncc3)ccc2c1 CHEMBL237352 IC50 250.0 nM
COc1ccc2cc(-c3nc(-c4ccc(S(C)(=O)=O)cc4)[nH]c3-c3ccncc3)ccc2c1 CHEMBL391890 IC50 250.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)cc2)n1 CHEMBL462082 IC50 250.0 nM
COc1cccc(C(=O)Nc2cc(-n3ccn4nc(-c5cccnc5)cc34)c(C)cc2C)c1 CHEMBL3917971 IC50 252.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CCO)sc4ncnc(N)c34)cc2)c1 CHEMBL197353 pIC50 257.04 nM
CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5cccc(C(F)(F)F)c5)s4)c2C3)CC1 CHEMBL213910 IC50 259.0 nM
COc1ccc2cc(-c3nc(-c4ccccc4C(F)(F)F)[nH]c3-c3ccncc3)ccc2c1 CHEMBL391889 IC50 260.0 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)N[C@@H](C)c3ccccc3)c2cc1OC CHEMBL270306 IC50 260.0 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 IC50 260.0 nM
CCCOc1cccc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 CHEMBL3928007 IC50 260.0 nM
CO/N=C(/c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4)C(C)C CHEMBL257793 IC50 264.0 nM
CCO/N=C/c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 CHEMBL257788 IC50 264.0 nM
Nc1cccc(-c2cn(Cc3ccc(-c4cccnc4)cc3)nn2)c1 CHEMBL4456856 IC50 265.72 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(Cc4ccncc4)sc4ncnc(N)c34)cc2)c1 CHEMBL369908 pIC50 269.15 nM
COc1ccc(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)c2c(N)noc12 CHEMBL430090 IC50 270.0 nM
CCCn1c2ccc(C(C)=O)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL255405 IC50 272.0 nM
COc1cc(Cc2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)[C@@H]1C[C@H]1c1ccccc1 CHEMBL416091 IC50 275.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(N)=O)cc2)cc1 CHEMBL193752 IC50 275.0 nM
Cc1ccc(NC(=O)c2cccc(-n3cccn3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3952312 IC50 275.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 280.0 nM
Cc1ccc(NC(=O)c2cc(C(C)(C)C)ccn2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3984523 IC50 280.0 nM
COc1cc2c(Oc3ccc(-c4cnc(Cc5ccccc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL505896 IC50 285.0 nM
CCCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 CHEMBL371225 pIC50 288.4 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3ccc(Cl)cc3)c2cc1C(N)=O CHEMBL409867 IC50 290.0 nM
CN1C[C@@H]2C[C@H]1CN2c1cc(F)c(-c2ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn23)c(F)c1 CHEMBL1276179 IC50 293.0 nM
Cc1cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)cc(S(N)(=O)=O)c1 CHEMBL3949425 IC50 297.0 nM
COc1ccc(-c2c(-c3cccc(NS(C)(=O)=O)c3)oc3ncnc(N)c23)cc1 CHEMBL194150 IC50 300.0 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc4ccccc4c3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17023 IC50 300.0 nM
CCN(CC)CCOc1ccc(Nc2cc(NC(=O)Nc3c(Cl)cccc3Cl)ncn2)cc1 CHEMBL253292 IC50 300.0 nM
CCn1c2ccc(/C(C)=N/OC)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL255283 IC50 300.0 nM
CCCCn1c2ccc(C(C)=O)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL255406 IC50 300.0 nM
O=C(O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2C(c2c(F)cccc2F)=NC3)cc1 CHEMBL259084 Kd 300.0 nM
Cn1ncc2c1CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(C4CCCC4)c13)CNC2=O CHEMBL1085295 IC50 300.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c(C)c2C)n1 CHEMBL465792 IC50 310.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 310.0 nM
CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1 CHEMBL1289926 Kd 310.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3928395 IC50 320.0 nM
COc1cc(-c2nc3ccccc3s2)ccc1Nc1ncnc2cc(OCCCN3CCN(C)CC3)c(OC)cc12 CHEMBL593221 IC50 330.0 nM
Cc1ccc(NC(=O)c2ccc(Cl)c(N3CCCCC3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3915640 IC50 330.0 nM
COc1ccc2cc(-c3c(-c4ccncc4)nc(-c4ccc(SC)cc4C)n3C)ccc2c1 CHEMBL237359 IC50 335.0 nM
CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 CHEMBL366241 pIC50 338.84 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc4cc(Br)ccc4c3)c(-c3ccncc3)[nH]2)cc1 CHEMBL400839 IC50 339.0 nM
Cn1cnc(-c2ccccc2)c1/C=C/c1ccnc(N)n1 CHEMBL526925 IC50 340.0 nM
Cc1cc(NC(=O)Nc2cccc(-c3ncn(C)c3-c3cc4c(N)ncnc4s3)c2)on1 CHEMBL1080479 IC50 340.0 nM
Cc1ccc(NC(=O)c2cc(C(C)C)ccc2O)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3892165 IC50 340.0 nM
Nc1ncnc2c1c(C(=O)c1ccc(NC(=O)Nc3c(F)cccc3F)cc1)cn2C1CCCC1 CHEMBL2386996 IC50 345.0 nM
CCc1ccccc1-c1nc(-c2ccc3cc(OC)ccc3c2)c(-c2ccncc2)[nH]1 CHEMBL236504 IC50 346.0 nM
CO/N=C(\C)c1ccc2c(c1)c1c3c(c4c(c1n2C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL255282 IC50 347.0 nM
COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3C)c2cc1OCCCN1CCN(C)CC1 CHEMBL595374 IC50 350.0 nM
Cn1ncc2c1CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(CCO)c13)CNC2=O CHEMBL1085296 IC50 350.0 nM
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)c(CO)n2C1CCCC1 CHEMBL302279 IC50 360.0 nM
COc1cccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL371889 IC50 360.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(Cl)cc(Cl)c2)cc1 CHEMBL381034 IC50 360.0 nM
COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3F)c2cc1OCCCN1CCN(C)CC1 CHEMBL594661 IC50 360.0 nM
Nc1ncnc2c1c(C(=O)c1cccc(NC(=O)Nc3c(F)cccc3F)c1)cn2C1CCCC1 CHEMBL2386994 IC50 361.0 nM
Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2N2CCCCC2)cc1Oc1ncccc1-c1ccncn1 CHEMBL276395 IC50 366.0 nM
Nc1nccc(/C=C/c2[nH]cnc2-c2ccccc2)n1 CHEMBL502279 IC50 370.0 nM
Nc1ncnc2sc(-c3c(-c4ccccc4)ncn3C[C@H]3CCCO3)nc12 CHEMBL1079772 IC50 370.0 nM
CC(C)c1ccc(C(=O)Nc2cc(CN3CCN(C)CC3)cc(C(F)(F)F)c2)cc1C#Cc1cnc2cnccn12 CHEMBL4168305 Kd 370.0 nM
CC(C)Cn1c2ccccc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL270827 IC50 372.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cn[nH]c3)cc12 CHEMBL3972985 IC50 380.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc3)c12 CHEMBL396107 Log IC50 380.19 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3ccccc3)c2cc1OC CHEMBL429430 IC50 386.0 nM
COc1ccc2cc(-c3nc(-c4ccccc4C)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236686 IC50 387.0 nM
CNc1nccc(-c2cc(C)cnc2Oc2cccc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)c2C)n1 CHEMBL218431 IC50 388.0 nM
COc1ccc2nc(-c3ccc(Nc4ncnc5cc(OCCCN6CCN(C)CC6)c(OC)cc45)cc3)sc2c1 CHEMBL593306 IC50 390.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 395.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(F)c2)cc1 CHEMBL196747 pIC50 398.11 nM
Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2N2CCOCC2)cc1Oc1ncccc1-c1ccncn1 CHEMBL220052 IC50 399.0 nM
CC(C)n1cc(-c2ccc(Oc3ccccc3N)cc2)c2c(N)ncnc21 CHEMBL303195 IC50 400.0 nM
CCN(Cc1ccccc1)c1nc(O)nc(Nc2ccc3ncsc3c2)n1 CHEMBL176078 IC50 400.0 nM
CNc1cc(-c2cccnc2Nc2c(C)ccc3c(Nc4ccc(C#N)cc4)nccc23)ncn1 CHEMBL570567 IC50 400.0 nM
Nc1ncnc2occ(-c3ccc(NC(=O)Nc4cccc(Oc5ccccc5)c4)cc3)c12 CHEMBL247790 Log IC50 407.38 nM
CO[C@@H]1[C@H](N(C)CCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4576489 Kd 408.0 nM
CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4c3OCCCN4)cc2)no1 CHEMBL4793380 IC50 408.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OCCN(C)C)c1 CHEMBL3964941 IC50 409.0 nM
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)c(C(=O)O)n2C1CCCC1 CHEMBL305748 IC50 410.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccc(Cl)cc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593275 IC50 410.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 CHEMBL376951 IC50 415.0 nM
Nc1ncnc2c1c(C(=O)c1cccc(NS(=O)(=O)c3c(F)cccc3F)c1)cn2C1CCCC1 CHEMBL2386993 IC50 423.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CN4CCOCC4)sc4ncnc(N)c34)cc2)c1 CHEMBL194842 pIC50 426.58 nM
CC(C)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc21 CHEMBL307982 IC50 430.0 nM
CC(C)n1cc(-c2ccc(Oc3ccc(C(=O)O)cc3)cc2)c2c(N)ncnc21 CHEMBL68773 IC50 430.0 nM
COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3ccc(C)cc3)c2cc1C(N)=O CHEMBL270954 IC50 430.0 nM
Nc1ncc2ccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc6c(c5)OCO6)CC4)cc3)cc2n1 CHEMBL4159588 IC50 432.35 nM
CCCn1c(-c2ccc([S+](C)[O-])cc2)nc(-c2ccncc2)c1-c1ccc2cc(OC)ccc2c1 CHEMBL237565 IC50 437.0 nM
Nc1ncnc2sc(-c3c(-c4ccccc4)ncn3Cc3ccccc3N3CCOCC3)nc12 CHEMBL1079773 IC50 440.0 nM
Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)O)c(C)c34)ccc2[nH]1 CHEMBL377300 Kd 440.0 nM
Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 CHEMBL572878 Kd 450.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)Nc3ccccc3)cc2C)n1 CHEMBL517559 IC50 460.0 nM
CNC(=O)CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 CHEMBL198601 pIC50 467.74 nM
Cn1cc2c(n1)CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(CC4CCCCC4)c13)CNC2=O CHEMBL1085292 IC50 469.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccc(C(F)(F)F)cc4[nH]3)cc2C)n1 CHEMBL468618 IC50 470.0 nM
O=C(CSc1nccc(Nc2ccc(N3CCOCC3)cc2)n1)c1ccc(F)cc1 CHEMBL4449189 IC50 480.0 nM
CC(C)Cn1cnc(-c2ccccc2)c1-c1nc2c(N)ncnc2s1 CHEMBL1079590 IC50 490.0 nM
N#Cc1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1C1CCCC1 CHEMBL68888 IC50 500.0 nM
Cc1ccc(NC(=O)c2cccc(OCC(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3903535 IC50 500.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)c3cccc(F)c3)cc2)cc1 CHEMBL372845 IC50 501.0 nM
Cc1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2)cc1Nc1ncccc1-c1ccncn1 CHEMBL222067 IC50 504.0 nM
CCOC(=O)c1cccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL195828 IC50 510.0 nM
COc1cc2c(Nc3ccc(-c4nc5cc(Cl)ccc5s4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL596292 IC50 510.0 nM
COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)c(Cl)c3)c2cc1OCCCN1CCN(C)CC1 CHEMBL604893 IC50 510.0 nM
COc1ccc2c(c1)C(=O)/C(=C/c1ccc(O)c(O)c1)O2 CHEMBL4087337 IC50 510.0 nM
COC(=O)c1cccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 CHEMBL1242107 pIC50 512.86 nM
COc1cc(-c2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2[nH]1 CHEMBL431609 IC50 520.0 nM
Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc1ncccc1-c1ccncn1 CHEMBL565884 IC50 520.0 nM
COc1cc(-c2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)OCc1ccccc1 CHEMBL47787 IC50 521.0 nM
COc1ccc(-c2c(-c3cccc(C(N)=O)c3)oc3ncnc(N)c23)cc1 CHEMBL363389 pIC50 537.03 nM
Nc1ncnc2sc(-c3c(-c4ccccc4)ncn3CC3CCCCC3)nc12 CHEMBL1079589 IC50 540.0 nM
Cn1ncc2c1CCc1c-2c2c(c3c4cc(C5CCCCO5)ccc4n(C)c13)CNC2=O CHEMBL1082437 IC50 554.0 nM
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3O)cc1)cn2C1CCCC1 CHEMBL67268 IC50 560.0 nM
COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1 CHEMBL24828 IC50 567.0 nM
Nc1ncnc2c1c(-c1nc3ccc(NS(=O)(=O)c4c(F)cccc4F)cc3[nH]1)cn2C1CCCC1 CHEMBL2387004 IC50 568.0 nM
COc1cc(-c2csc3c(/C=C/CN[C@H]4CC[C@@H](N)CC4)cnc(N)c23)ccc1NC(=O)c1cc2ccccc2n1C CHEMBL395666 IC50 570.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(C(C)C)sc4ncnc(N)c34)cc2)c1 CHEMBL371890 pIC50 575.44 nM
NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1C1CCCC1 CHEMBL67598 IC50 580.0 nM
COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(Cl)cc5)cccc4c3)c2cc1OC CHEMBL429743 IC50 580.0 nM
Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3933531 IC50 580.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(Nc3nc4ccccc4[nH]3)c(C)c2)n1 CHEMBL462083 IC50 590.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3OC(F)(F)F)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593245 IC50 590.0 nM
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)cn2C1CCCC1O CHEMBL419082 IC50 600.0 nM
COc1ccccc1Oc1ccc(-c2cn(C3CCCC3)c3ncnc(N)c23)cc1 CHEMBL66102 IC50 600.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(N(C)C)cc2)cc1 CHEMBL194057 IC50 600.0 nM
O=C(NCCc1ccc(O)c(Br)c1)/C(Cc1cc(Br)c(O)c(Oc2ccc(CCNC(=O)/C(Cc3cc(Br)c(O)c(-c4cc(C/C(=N\O)C(=O)NCCc5ccc(O)c(Br)c5)cc(Br)c4O)c3)=N/O)cc2Br)c1)=N/O CHEMBL2333163 IC50 600.0 nM
Cc1ccc(NC(=O)c2cccc(N(C)C)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3938204 IC50 600.0 nM
CN1CCN([C@H]2CC[C@H](n3nc(-c4ccc(Nc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL46785 IC50 606.0 nM
CCOCCOc1cccc(C(=O)Nc2cc(-n3ccn4nc(-c5cccnc5)cc34)c(C)cc2C)c1 CHEMBL3951546 IC50 607.0 nM
CC(O)c1c(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc2n1C1CCCC1 CHEMBL67560 IC50 610.0 nM
COc1cc2c(Nc3ccc(-c4nc5ccc(Cl)cc5s4)cc3F)ncnc2cc1OCCCN1CCN(C)CC1 CHEMBL593909 IC50 615.0 nM
CN(C)C1CCN(c2ccc(C(F)(F)F)cc2NC(=O)c2cc(C#Cc3cnc(N)nc3)ccc2F)CC1 CHEMBL221193 IC50 620.0 nM
CNC(=O)c1ccc(C#Cc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)cn1 CHEMBL450024 IC50 623.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(CN4CCN(C)CC4)sc4ncnc(N)c34)cc2)c1 CHEMBL372388 IC50 630.0 nM
CNc1nccc(-c2cccnc2Oc2ccc(NC(=O)c3cccc(C(F)(F)F)c3)cc2C)n1 CHEMBL1242977 IC50 630.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 630.0 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 CHEMBL4568087 IC50 660.0 nM
COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3)c2cc1OCCCN1CCN(C)CC1 CHEMBL593292 IC50 670.0 nM
Cc1ccc(NC(=O)c2cccc(-c3cccc(C#N)c3)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3966953 IC50 670.0 nM
CC(C)n1cc(-c2ccc(Oc3ccccc3C(=O)O)cc2)c2c(N)ncnc21 CHEMBL67211 IC50 677.0 nM
Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(OCCN4CCCC4)cc3)nnc2c1 CHEMBL436137 IC50 678.0 nM
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=S)Nc4cccc(C(F)(F)F)c4)cc3)cc2[nH]1 CHEMBL244287 IC50 680.0 nM
Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OCCO)c1 CHEMBL3900087 IC50 687.0 nM
CC(C)(Nc1nc(NO)nc(Nc2ccc3ncsc3c2)n1)c1ccccc1 CHEMBL177298 IC50 700.0 nM
Cn1ncc2c1CCc1c-2c2c(c3c1[nH]c1ccc(C4CCCCO4)cc13)CNC2=O CHEMBL1083071 IC50 715.0 nM
CN[C@H]1CC2OC([C@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(O)=NC4 CHEMBL3975634 IC50 719.8 nM
Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)cc2)c1 CHEMBL196363 IC50 720.0 nM
CC(=O)c1ccc2c(c1)c1c3c(c4c(c1n2C(C)C)CCc1nn(C)cc1-4)C(=O)NC3 CHEMBL255404 IC50 726.0 nM
COc1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)cc(OC)c1OC CHEMBL201511 IC50 740.0 nM
N#Cc1c(Oc2ccc(F)c(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)ccc2nc(NC(=O)C3CC3)sc12 CHEMBL3125890 IC50 740.0 nM
Cc1ccc(NC(=O)c2ccc(F)c(C(F)(F)F)c2)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3980186 IC50 740.0 nM
Nc1ncnc2c1c(C(=O)c1ccc(NS(=O)(=O)c3c(F)cccc3F)cc1)cn2C1CCCC1 CHEMBL2386995 IC50 745.0 nM
COc1cc(Nc2nccc(Nc3cnc4ccccc4c3)n2)cc(OC)c1OC CHEMBL1760035 IC50 746.0 nM
CN1CCN([C@H]2CC[C@H](n3nc(-c4ccc(Oc5ccccc5)cc4)c4c(N)ncnc43)CC2)CC1 CHEMBL44577 IC50 750.0 nM
Cc1cccc(C)c1-n1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n2c3ccccc3nc12 CHEMBL410295 IC50 750.0 nM
COc1cc(OC)cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 CHEMBL3977173 IC50 770.0 nM
O=C(NCCc1ccc(O)c(Br)c1)/C(Cc1cc(Br)c(O)c(-c2cc(C/C(=N/O)C(=O)NCCc3ccc(O)c(Br)c3)cc(Br)c2O)c1)=N\O CHEMBL505637 IC50 800.0 nM
COc1ccc2cc(-c3nc(-c4ccccc4C(C)C)[nH]c3-c3ccncc3)ccc2c1 CHEMBL236505 IC50 836.0 nM
COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3C)c2cc1OC CHEMBL514942 IC50 840.0 nM
CN(c1ccc(F)c(NC(=O)c2cccc(OC(C)(C)C#N)c2Cl)c1)c1ccc2nc(NC(=O)C3CC3)sc2n1 CHEMBL2204532 IC50 840.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 CHEMBL196499 IC50 850.0 nM
COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NS(=O)(=O)c3cccc(Cl)c3)cc2)cc1 CHEMBL365773 IC50 851.0 nM
Cc1cccc(NC(=O)Nc2ccc(-c3c(Cc4ccccc4)sc4ncnc(N)c34)cc2)c1 CHEMBL372755 pIC50 870.96 nM
COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3O)c2cc1OCCCN1CCN(C)CC1 CHEMBL593294 IC50 880.0 nM
COc1cc(-c2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NS(=O)(=O)Nc1ccccc1 CHEMBL46176 IC50 888.0 nM
Cc1ccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)cc1 CHEMBL198267 IC50 890.0 nM
Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccccc2Cl)cc1 CHEMBL194321 pIC50 891.25 nM
CC(C)(C)n1cc(-c2ccc(Oc3ccc(N)cc3)cc2)c2c(N)ncnc21 CHEMBL69068 IC50 900.0 nM
Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5cc(OC(F)(F)F)ccc5Br)CC4)cc3)c12 CHEMBL4093247 IC50 904.52 nM
COc1cc(-c2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)CC(C)(C)c1ccccc1 CHEMBL295528 IC50 910.0 nM
COc1ccccc1NC(=O)Nc1ccc(-c2c(C)sc3ncnc(N)c23)cc1 CHEMBL445394 pIC50 912.01 nM
COc1cc(-c2nn([C@H]3CC[C@H](N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)Nc1ccccc1 CHEMBL45651 IC50 933.0 nM
Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F CHEMBL191003 Kd 950.0 nM
O=C1/C(=C/c2ccc(O)c(O)c2)Oc2cc(O)ccc21 CHEMBL490355 IC50 950.0 nM
COc1cc2c(Oc3ccc(Nc4nn(C)cc4C(=O)NC4CCCCC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL5197792 Kd 950.0 nM
CC(C)n1cc(-c2ccc(Oc3ccc(C#N)cc3)cc2)c2c(N)ncnc21 CHEMBL71985 IC50 970.0 nM
Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2F)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3951276 IC50 980.0 nM
Cc1ccc(NC(=O)c2cc(N3CCCC3)ccc2Cl)cc1-n1ccn2nc(-c3cccnc3)cc12 CHEMBL3946991 IC50 995.0 nM