CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(CN4CCCC4)c3)c2n1 CHEMBL2424781 MEC 0.03 nM
Cc1c(C2CC3(CNCCO3)C2)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5266091 EC50 0.07 nM
Cc1nccc(-c2cc3[nH]nc(N[C@H]4CCNC[C@@H]4F)c3cc2C2CC2)c1F CHEMBL5079910 IC50 0.1 nM
Cc1c(C2CC3(CNCCO3)C2)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5267703 EC50 0.11 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCCN2CCCCC2)nc1 CHEMBL1836893 EC50 0.2 nM
Cc1nc2c3c(c(-c4[nH]c5sc([C@@H]6C[C@@H]7C[C@H]6CN7CC(N)=O)c(C)c5c4C(C)C)cn2n1)CCC3 CHEMBL5277999 EC50 0.24 nM
Cc1c([C@@H]2C[C@@H]3C[C@H]2CN3CCS(C)(=O)=O)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5273537 EC50 0.27 nM
COCCOc1cc2c(c(N)n1)NC(=O)CN2Cc1ccc(CN2CCCC2)cc1 CHEMBL2426779 MEC 0.32 nM
CCCCOc1nc(N)c2[nH]c(=O)c(=O)n(Cc3ccc(CN4CCCC4)cc3)c2n1 CHEMBL2426786 MEC 0.32 nM
Cc1c(-c2cnc3c(c2)CNCC3)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5291249 EC50 0.33 nM
Cc1nccc(-c2cc3[nH]nc(NC4CCN(C)CC4)c3cc2C2CC2)c1F CHEMBL5090067 IC50 0.39 nM
CN1CCN(CCN(C)c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 CHEMBL1836892 EC50 0.4 nM
Cc1c(C2CC3(CCNC3)C2)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5272936 EC50 0.46 nM
CC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1 CHEMBL5282747 pEC50 0.5012 nM
COc1ccc(Cn2ccc3nc(N)nc(NCc4cc(C)on4)c32)nc1OC CHEMBL4078859 EC50 0.6 nM
O=c1ccc(-c2cc(C(F)(F)F)c3nn([C@H]4CCNC[C@@H]4F)cc3c2)c2n1CCC2 CHEMBL4641633 IC50 0.62 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCNCC3)c2n1 CHEMBL3546576 pEC50 0.631 nM
CCCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCN3CCCCC3)c2n1 CHEMBL5281683 pEC50 0.631 nM
COc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1ccnc(C)c1F CHEMBL5085458 IC50 0.67 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 CHEMBL5201891 IC50 0.7 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCN(C(C)C)CC3)c2n1 CHEMBL5284817 pEC50 0.7943 nM
CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCN3CCCCC3)c2n1 CHEMBL5289715 pEC50 0.7943 nM
COc1cc(-c2cc3[nH]c4ccc(C5CCNCC5)cc4c3c(C)c2C)cn2ncnc12 CHEMBL4849186 IC50 0.8 nM
Cc1cc(-c2[nH]c3cc(F)c(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5182126 IC50 0.8 nM
CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1 CHEMBL4297492 pEC50 0.8913 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)c(F)c3c2C(C)C)cc(C)n1 CHEMBL5176097 IC50 0.9 nM
CCN(CC)CCN(C)c1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1836891 EC50 1.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc(CN3CCCC3)cc1)CC(=O)N2 CHEMBL2424777 MEC 1.0 nM
COc1cccc(Cn2ccc3nc(N)nc(NCc4cc(C)on4)c32)n1 CHEMBL4103135 EC50 1.0 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(OC6CCNCC6)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4870936 IC50 1.0 nM
Cc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1ccnc(C)c1F CHEMBL5085289 IC50 1.0 nM
CCCCOc1nc(N)c2[nH]c(C#N)c(Cc3ccc(CN4CCCC4)nc3)c2n1 CHEMBL5278024 EC50 1.0 nM
Nc1nc2nc3c1nc(O)n3Cc1ccc(-c3ccc(CNC4CCC4)cc3)c(c1)OCCCCO2 CHEMBL5265854 EC50 1.0 nM
CC(C)Oc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1 CHEMBL5270358 pEC50 1.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)CN5CCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5435782 IC50 1.0 nM
CC[P@@](C)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1 CHEMBL5437420 EC50 1.0 nM
COc1cc2c(C(=O)N3CCN(C)CC3)n[nH]c2cc1-c1cc(C)nc(C)c1 CHEMBL5077018 IC50 1.1 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(N6CC[C@](C)(N)C6)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4850118 IC50 1.3 nM
COc1cc(-c2cc(C)c3c(c2)[nH]c2ccc(C4CCNCC4)cc23)cn2ncnc12 CHEMBL4846672 IC50 1.4 nM
CCC[C@@H](C)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC)c12 CHEMBL5433689 IC50 1.4 nM
CN(C)CCN1CCN(c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 CHEMBL1836889 EC50 1.5 nM
Cc1cc(-c2cc(C)c3c(c2)[nH]c2ccc(C4CCN(CC(C)(C)O)CC4)cc23)cc(C)n1 CHEMBL4854009 IC50 1.5 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN3CCCCCC3)c2n1 CHEMBL5274995 pEC50 1.585 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCCN3CCCCC3)c2n1 CHEMBL5285546 pEC50 1.585 nM
CN(CCN1CCCCC1)c1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1836890 EC50 1.6 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(N2CCC[C@H]2CN2CCCC2)nc1 CHEMBL1836881 EC50 1.7 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCCN2CCCC2)nc1 CHEMBL1836885 EC50 1.7 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(N6C[C@@H]7C[C@H]6CN7)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4878670 IC50 1.7 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(F)n1 CHEMBL5169693 IC50 1.8 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNC)cc1 CHEMBL5395556 EC50 1.8 nM
COc1cc(-c2cc3[nH]c4ccc(C5CCNCC5)cc4c3cc2C)cn2ncnc12 CHEMBL4872385 IC50 1.9 nM
COc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 CHEMBL5201981 IC50 1.9 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5290147 pEC50 1.995 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CNCc4ccncc4)cc3OC)c12 CHEMBL5429027 EC50 2.0 nM
CN[C@H](C)C(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5429312 IC50 2.0 nM
CN[C@@H](C)C(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5405310 IC50 2.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)[C@@H]5CNCCO5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5430709 IC50 2.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CN(C)C)cc1OC CHEMBL5277107 pEC50 2.291 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccnc(N2CCC[C@H]2CN2CCCC2)c1 CHEMBL1837074 EC50 2.3 nM
Cc1cc(-c2cc(C)c3c(c2)[nH]c2ccc(C4CCNCC4)cc23)cc(C)n1 CHEMBL4865326 IC50 2.4 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCCNC3)c2n1 CHEMBL5290071 pEC50 2.512 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN3CCN(C(C)C)CC3)c2n1 CHEMBL5291025 pEC50 2.512 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c(C)cn1 CHEMBL5178588 IC50 2.6 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN(CC)CC)cc1 CHEMBL5413112 EC50 2.6 nM
COCCCN1CCN(c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 CHEMBL1836879 EC50 2.7 nM
CN1CCN(c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 CHEMBL1836887 EC50 2.7 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(N6C[C@H]7C[C@@H]6CN7)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4849957 IC50 2.7 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(Cn2ccnc2)cc1OC CHEMBL5281794 pEC50 2.754 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCc2cc[nH]c2)cc1 CHEMBL5435125 EC50 2.8 nM
CCCCOc1cc2c([nH]c(=O)c(=O)n2Cc2ccc(CN3CCCC3)cc2)c(N)n1 CHEMBL2426781 MEC 3.0 nM
CCCCNc1nc(N)c2[nH]c(=O)c(=O)n(Cc3cccc(CN4CCCC4)c3)c2n1 CHEMBL2426787 MEC 3.0 nM
CCCCOc1nc(N)c2[nH]c(=O)c(=O)n(Cc3cccc(CN4CCCC4)c3)c2n1 CHEMBL2426789 MEC 3.0 nM
CCC[C@H](C)Oc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2426802 MEC 3.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc(-c3ccc(CN4CCCC4)cc3)cc1)CC(=O)N2 CHEMBL2424769 MEC 3.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc(-c3cccc(CN4CCCC4)c3)cc1)CC(=O)N2 CHEMBL2424770 MEC 3.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc(CCCN3CCCC3)nc1)CC(=O)N2 CHEMBL2424771 MEC 3.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc3c(c1)CCN(C(C)C)C3)CC(=O)N2 CHEMBL2424772 MEC 3.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc3c(c1)CN(C(C)C)CC3)CC(=O)N2 CHEMBL2424773 MEC 3.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2424780 MEC 3.0 nM
[2H]c1ccc2c(N3C[C@@H]4CN(c5ncc(N6CC7(CC(N)C7)C6)cc5C)CCN4[C@H](C)C3)ccc(C#N)c2n1 CHEMBL4755291 IC50 3.0 nM
Cc1cc(-c2ccnc3[nH]ncc23)cnc1OCC12CCC(O)(CC1)CC2 CHEMBL4740968 IC50 3.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC(C)(N)C6)ccc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5094595 IC50 3.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC(N)C6)ccc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5081117 IC50 3.0 nM
COc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1ccncc1 CHEMBL5086681 IC50 3.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCC(C)(C)O)cc1 CHEMBL5400465 EC50 3.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5421376 IC50 3.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CNC)cc1OC CHEMBL5279190 pEC50 3.02 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN(C)C)cc1 CHEMBL5406627 EC50 3.4 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCCCCO)cc1 CHEMBL5420662 EC50 3.5 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCO)cc1 CHEMBL5429987 EC50 3.8 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN2CCNCC2)cc1 CHEMBL5427563 EC50 3.8 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2CN(c3cncc4c3CCNC4)CCN21 CHEMBL4799678 IC50 4.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6C[C@H]7NCCO[C@@H]7C6)cnc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5076307 IC50 4.0 nM
C[C@H]1CN(c2ccc(C#N)c3nccnc23)C[C@@H]1C(=O)NC1CCN(C)CC1 CHEMBL5193543 IC50 4.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC5CCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5430815 IC50 4.0 nM
CC(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5399685 IC50 4.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCOCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5409292 IC50 4.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)CN5CCCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5403827 IC50 4.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)[C@@H]5COCCN5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5417170 IC50 4.0 nM
CCC[P@](C)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(NCCN(C)C)nc3)c2n1 CHEMBL5402083 EC50 4.0 nM
COCCN1CCN(c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 CHEMBL1836888 EC50 4.1 nM
CCCCCNCc1ccc(Cn2c(CCCC)nc3c(N)nc4ccsc4c32)cc1 CHEMBL5409194 EC50 4.3 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccc(OC)c(OC)c4)c(C(C)C)c3c2)CC1 CHEMBL4636498 IC50 4.8 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN2CCN(CCN3CCOCC3)CC2)cc1 CHEMBL5417951 EC50 4.8 nM
Cc1cc(-c2cc3[nH]nc(N[C@@H]4CCNC[C@H]4F)c3cc2C2CC2)cc(C)n1 CHEMBL5091113 IC50 4.9 nM
COCCNC(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1 CHEMBL484765 EC50 5.0 nM
C[C@@H]1CN(c2ccc(C#N)n3nccc23)C[C@H](CN2CC3(C2)OCc2cc(N4CC5(CN(C)C5)C4)ccc23)O1 CHEMBL5092293 IC50 5.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC(C)(N)C6)ncc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5091915 IC50 5.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCC(C)(C)N2CCOCC2)cc1 CHEMBL5403665 EC50 5.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5407646 IC50 5.0 nM
CC[P@](C)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(C)CC4)nc3)c2n1 CHEMBL5430849 EC50 5.0 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCCC2)cc1OC CHEMBL5267123 pEC50 5.012 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(C)CC4)nc3)c2n1 CHEMBL2315166 EC50 5.4 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN2CCNCC2)cc1OC CHEMBL5276429 pEC50 5.888 nM
Cc1cnc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)o1 CHEMBL4070546 EC50 6.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)no1 CHEMBL4094458 EC50 6.0 nM
COc1cccnc1Cn1ccc2nc(N)nc(OCc3ncc(C)o3)c21 CHEMBL4074704 EC50 6.0 nM
COc1cccnc1Cn1ccc2nc(N)nc(NCc3cc(C)on3)c21 CHEMBL4095178 EC50 6.0 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@H]2CN(c3cncc4c3CCNC4)CCN21 CHEMBL4745246 IC50 6.0 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2CN(CCc3ccc(N4C[C@@H](N)[C@@H](F)C4)nc3)CCN21 CHEMBL4747784 IC50 6.0 nM
Cn1nc(-c2ccc(OCC34CCC(N)(CC3)CC4)c(F)c2)c2cnc(N)nc21 CHEMBL4748638 IC50 6.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)CN(C)C)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5432728 IC50 6.0 nM
CC[P@@](C)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(C)CC4)nc3)c2n1 CHEMBL5408551 EC50 6.0 nM
CC[P@](C)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1 CHEMBL5396299 EC50 6.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5190495 IC50 6.1 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1O CHEMBL5270503 pEC50 6.31 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5267235 pEC50 6.31 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN3CCCCC3)c2n1 CHEMBL5282406 pEC50 6.31 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(N6CCC7(CNC7)C6)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4850085 IC50 6.5 nM
CN(C)CCNc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1836883 EC50 6.6 nM
CN(C)CCN(C)c1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1836886 EC50 6.6 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCc2ccc(CN)cc2)cc1 CHEMBL5410888 EC50 6.6 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(OCCN2CCCC2)nc1 CHEMBL1836884 EC50 6.9 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(C)CC4)cc3)c2n1 CHEMBL2315155 EC50 7.0 nM
[2H]c1ccc2c(N3CC4CN(c5ncc(N6CCOC[C@H](N)C6)cc5C)CCN4[C@@H](C)C3)ccc(C#N)c2n1 CHEMBL4795549 IC50 7.0 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2CN(c3cccc4c3CCNC4)CCN21 CHEMBL4760220 IC50 7.0 nM
CNC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5434008 IC50 7.0 nM
CC[P@](C)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(S(C)(=O)=O)CC4)nc3)c2n1 CHEMBL5440926 EC50 7.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1 CHEMBL2315158 EC50 7.2 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c(C)c(C)n1 CHEMBL5183412 IC50 7.2 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCC(N(C)C)C4)nc3)c2n1 CHEMBL2315165 EC50 7.4 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCCCC4)cc3)c2n1 CHEMBL2315153 EC50 7.6 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN)cc1 CHEMBL5409349 EC50 7.6 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCN3CCCCC3)c2n1 CHEMBL5281690 pEC50 7.943 nM
Nc1nc(NCc2cc(C3CC3)on2)c2c(ccn2Cc2ccccn2)n1 CHEMBL4073895 EC50 8.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC7(CNCCO7)C6)ccc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5075053 IC50 8.0 nM
C[C@@H]1CN(c2ccc(C#N)n3ncc(F)c23)C[C@H](C(=O)NC2CCN(C)CC2)O1 CHEMBL5197568 IC50 8.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CN)cc1 CHEMBL1271706 EC50 8.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NS(C)(=O)=O)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5423692 IC50 8.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(OC)c(CC(=O)OC)c3)c2n1 CHEMBL1092654 EC50 8.1 nM
Cc1cc(-c2[nH]c3cc(C)c(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5201441 IC50 8.2 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O CHEMBL1082983 EC50 8.58 nM
CCNCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O CHEMBL1085742 EC5 8.6 nM
CC1(N)CCN(c2ccc3c(n2)CN2CCN(c4ccc(C#N)c5ncccc45)C[C@@H]32)CC1 CHEMBL4863896 IC50 8.7 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN2CCN(CCN)CC2)cc1 CHEMBL5433130 EC50 8.8 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCN2CCSCC2)cc1 CHEMBL5398057 EC50 8.9 nM
CN1CCN(CC2CCCN2c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 CHEMBL1836880 EC50 9.0 nM
Cc1cnc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)s1 CHEMBL4086717 EC50 9.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4ccc(F)cn4)c23)no1 CHEMBL4072841 EC50 9.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4ncccc4F)c23)no1 CHEMBL4099725 EC50 9.0 nM
Cc1cc(-c2cc3[nH]nc(N[C@H]4CCNC[C@@H]4F)c3cc2C2CC2)cc(C)n1 CHEMBL5078689 IC50 9.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N(C)C)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5406817 IC50 9.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N(C)C)cc3)c2n1 CHEMBL2315152 EC50 9.3 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCC(N(C)C)CC4)nc3)c2n1 CHEMBL2315164 EC50 9.4 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CNCCO)cc1OC CHEMBL5284404 pEC50 9.772 nM
COCCOc1nc(N)c2nc(S)n(Cc3cccc(CP(C)(=O)O)c3)c2n1 CHEMBL519690 EC50 10.0 nM
Nc1nc(NCc2ccccc2)nc2c1nc(O)n2Cc1cccc(CP(=O)(O)O)c1 CHEMBL483597 EC50 10.0 nM
CCCCOc1cc2c([nH]c(=O)c(=O)n2Cc2ccc(-c3ccc(CN4CCCC4)cc3)cc2)c(N)n1 CHEMBL2426778 MEC 10.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccc(CN3CCCC3)cc1)C(C)C(=O)N2 CHEMBL2426795 MEC 10.0 nM
CCC(CC)COc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2426799 MEC 10.0 nM
Nc1nc(OCC2CCOCC2)nc2c1NC(=O)CN2Cc1cccc(CN2CCCC2)c1 CHEMBL2426798 MEC 10.0 nM
CCCCNc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2424766 MEC 10.0 nM
COCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2424768 MEC 10.0 nM
COCCNC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5432727 IC50 10.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5C[C@@H](C)O[C@@H](C)C5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5419406 IC50 10.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(CC(=O)OC)cc3)c2n1 CHEMBL1089225 EC50 10.3 nM
COc1cc(-c2cc3[nH]nc(NC4CCN(C)CC4)c3cc2OC)ccn1 CHEMBL5089636 IC50 11.0 nM
CCOCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN)cc1 CHEMBL5424140 EC50 11.0 nM
CCOC(=O)COc1ccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)NCCN2CCCCC2)cc1 CHEMBL5273504 EC50 11.2 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC)c12 CHEMBL5419663 IC50 12.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCC5(CC4)CN(C4CCOCC4)C5)cc3OC)c12 CHEMBL5404211 EC50 12.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NCC(F)F)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5400499 IC50 12.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CNC)cc1OC CHEMBL5270808 pEC50 12.02 nM
CCc1c(-c2ccnc(C)c2)[nH]c2cc(F)c(C3CCNCC3)c(F)c12 CHEMBL5174201 IC50 13.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCN)cc1 CHEMBL5411630 EC50 13.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(C4CCNCC4)cc3OC)c12 CHEMBL5417891 EC50 13.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(C5CCOCC5)CC4)cc3OC)c12 CHEMBL5435264 EC50 13.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)[C@H]5COCCN5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5411489 IC50 13.0 nM
Cc1cc(=O)n(C)cc1-c1cc(C)c2nn(C3CCNCC3)cc2c1 CHEMBL4642538 IC50 14.0 nM
CCc1c(-c2ccnc(C)c2)[nH]c2ccc(C3CCNCC3)c(C)c12 CHEMBL5180395 IC50 14.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(C)CC4)cc3OC)c12 CHEMBL5427289 EC50 14.0 nM
CCOc1nc(C)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3)c2n1 CHEMBL5196933 IC50 15.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(Cn4ccnc4)cc3OC)c12 CHEMBL5407132 EC50 15.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCCCN(C)C)nc3)c2n1 CHEMBL2315160 EC50 15.2 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5287028 pEC50 15.85 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1OC CHEMBL5266634 pEC50 15.85 nM
CCCN(CCC)C(=O)C1=Cc2ccc(-c3cccc(C(=O)CC)c3)cc2N=C(N)C1 CHEMBL5435648 EC50 16.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(CCN(C)C)Cc1cccc(OC(C)(C)C(=O)OC)c1 CHEMBL5290342 EC50 16.6 nM
Cc1cc(-c2[nH]c3cc(C(F)(F)F)c(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5176324 IC50 17.0 nM
CCNCC(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5405740 IC50 17.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(C(C)C)CC4)cc3OC)c12 CHEMBL5426019 EC50 18.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc1 CHEMBL5439905 EC50 18.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCN(C)CC5=O)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5423714 IC50 19.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CNC2CN(C)C2)cc1OC CHEMBL5281565 pEC50 19.05 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CNC2CNC2)cc1OC CHEMBL5281658 pEC50 19.5 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCCN(C)C)nc3)c2n1 CHEMBL2315159 EC50 19.6 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCO)cc1OC CHEMBL5265885 pEC50 19.95 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCO)cc1OC CHEMBL5275266 pEC50 19.95 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCS(C)(=O)=O)cc1OC CHEMBL5285459 pEC50 19.95 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1OC CHEMBL5279696 pEC50 19.95 nM
CCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)OCC2CCN(C)CC2)ccc1OC CHEMBL5283468 pEC50 19.95 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1OC CHEMBL5291339 pEC50 19.95 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN3CCCC3)c2n1 CHEMBL5291390 pEC50 19.95 nM
CC(C)c1cc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)no1 CHEMBL4067994 EC50 20.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4cc(C(F)(F)F)ccn4)c23)no1 CHEMBL4060138 EC50 20.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4cc(Cl)ccn4)c23)no1 CHEMBL4098533 EC50 20.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3OC)nc12 CHEMBL5090317 EC50 20.0 nM
CCCCc1nc2c(N)nc3cc(C)sc3c2n1Cc1ccc(CN)cc1 CHEMBL5406954 EC50 20.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN2CCC(c3ccncc3)CC2)cc1 CHEMBL5397902 EC50 20.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNC2CC(F)(F)C2)cc1 CHEMBL5420320 EC50 20.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5431871 IC50 20.0 nM
CCN(CC)CC(=O)N(CCCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1 CHEMBL5273693 EC50 20.4 nM
CCOC(=O)C(C)(C)Oc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)CCN(C)C)c1 CHEMBL5280480 EC50 20.9 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCC5(CC4)CN(C(C)C)C5)cc3OC)c12 CHEMBL5407698 EC50 21.0 nM
Cc1cc(-c2ccc3c(c2)[nH]c2ccc(C4CCNCC4)cc23)cc(C)n1 CHEMBL4856345 IC50 22.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C2CC2)n1 CHEMBL5197134 IC50 22.0 nM
CCOC(=O)COc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5266002 EC50 22.7 nM
CCOC(=O)C(CC)Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5266058 EC50 23.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CN4CCNCC4)cc3OC)c12 CHEMBL5431826 EC50 23.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3)nc12 CHEMBL5077799 EC50 24.0 nM
CCc1c(-c2ccnc(C)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5179092 IC50 24.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CN4CCCCC4)cc3OC)c12 CHEMBL5418486 EC50 24.0 nM
CCOC(=O)C(C)Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5279923 EC50 24.2 nM
CCN(CC)CC(=O)N(CCCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)(C)C)c1 CHEMBL5280741 EC50 24.7 nM
Cn1nc(-c2ccc(OC[C@H]3CC[C@H](N)CC3)c(F)c2)c2cnc(N)nc21 CHEMBL4783510 IC50 25.0 nM
CCOc1nc(N)c2nc(-c3cncc(F)c3)n(Cc3ccc(CN4C[C@@H]5C[C@H]4CN5C)cc3)c2n1 CHEMBL5183721 IC50 25.0 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5284883 pEC50 25.12 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCC(N(C)C)CC2)cc1OC CHEMBL5274939 pEC50 25.12 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCN(C)CC2)cc1F CHEMBL5290842 pEC50 25.12 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN(C)C)cc1 CHEMBL5286122 pEC50 25.12 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(F)c(CC(=O)OC)c3)c2n1 CHEMBL1093466 EC50 25.7 nM
CCC(Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1)C(=O)OC CHEMBL5273317 EC50 25.9 nM
CN(C)CCOc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1836882 EC50 26.9 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCNC(C)=O CHEMBL3924480 EC50 27.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CC5(COC5)C4)cc3)nc12 CHEMBL5079043 EC50 27.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCc2ccccc2)cc1 CHEMBL5435121 EC50 27.0 nM
CCOC(=O)COc1cc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)ccc1C CHEMBL5284955 EC50 27.3 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1F CHEMBL5279529 EC50 27.9 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(C3CCNCC3)nc12 CHEMBL4641604 IC50 28.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CCN(C)C)cc3)nc12 CHEMBL5094792 EC50 28.0 nM
CC(C)c1c(-c2ccnc(C(F)(F)F)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5179188 IC50 28.0 nM
Cc1nccc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c1C CHEMBL5184042 IC50 28.0 nM
CCCCNc1nc(N)c2nc(O)n(Cc3ccc(OC)nc3)c2n1 CHEMBL426485 EC50 28.1 nM
COCCNc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1837075 EC50 28.6 nM
CC(C)c1c(-c2ccncc2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5188600 IC50 29.0 nM
CCCCOc1cc2c([nH]c(=O)c(=O)n2Cc2ccc(-c3cccc(CN4CCCC4)c3)cc2)c(N)n1 CHEMBL2426780 MEC 30.0 nM
CCCCOc1cc2c([nH]c(=O)c(=O)n2Cc2cccc(CN3CCCC3)c2)c(N)n1 CHEMBL2426783 MEC 30.0 nM
CCCCOc1cc2c(c(N)n1)NC(=O)CN2Cc1ccc(CN2CCCC2)cc1 CHEMBL2426782 MEC 30.0 nM
Nc1nc(OCCC2CC2)nc2c1NC(=O)CN2Cc1cccc(CN2CCCC2)c1 CHEMBL2424763 MEC 30.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCCC3)c1)CC(=O)N2 CHEMBL2424774 MEC 30.0 nM
CCCCNc1nc(N)nc2ccn(Cc3ccsc3)c12 CHEMBL4079841 EC50 30.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4ccc(C(F)(F)F)cn4)c23)no1 CHEMBL4088372 EC50 30.0 nM
CCOC(=O)C1=Cc2ccc(-c3cccc(C#N)c3)cc2N=C(N)C1 CHEMBL5275885 EC50 30.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC5COC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5398965 IC50 30.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3cccc(N4CCCCC4)c3)c2n1 CHEMBL2315156 EC50 30.1 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCc2ccccc2)nc1 CHEMBL1836895 EC50 31.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5277228 pEC50 31.62 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCC2CCN(C)CC2)cc1F CHEMBL5268725 pEC50 31.62 nM
CCCCCNc1nc(N)nc(C)c1Cc1cccc(CC(=O)OCCCCN(C)C)c1 CHEMBL5282311 pEC50 31.62 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC)c1 CHEMBL5289435 EC50 31.7 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(N2CCOCC2)nc1 CHEMBL1836896 Activity 32.0 nM
CCCCNc1nc(N)c2nc(O)n(Cc3ccc(C)nc3)c2n1 CHEMBL383765 EC50 32.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCCC4)cc3)nc12 CHEMBL5083795 EC50 33.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OC(C)(C)C(=O)OC)c1 CHEMBL5283748 EC50 33.1 nM
Cc1cc(-c2cc(C)c3nn(C4CCNCC4)cc3c2)cn(C)c1=O CHEMBL4643502 IC50 34.0 nM
CCCCOc1nc(N)c2nc(O)n(Cc3ccc(C(=O)NCCOCCNC(=O)CC[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)/C=C/c4ccc(O)c(OC)c4)C(C)C)C(=O)OCC)cc3)c2n1 CHEMBL5185123 EC50 36.0 nM
CCOC(=O)COc1ccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)cc1 CHEMBL5267937 EC50 38.3 nM
Cc1cc(OCCOCCOCCC(F)(F)P(=O)(O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1 CHEMBL3827257 EC50 39.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCCNC(=O)OC(C)(C)C)cc1 CHEMBL5405415 EC50 39.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCC(CC(=O)OCC)CC1 CHEMBL5266813 pEC50 39.81 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN(C)C CHEMBL5272350 pEC50 39.81 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCc2scnc2C)cc1OC CHEMBL5284582 pEC50 39.81 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1F CHEMBL5283655 pEC50 39.81 nM
CC[C@H](O)CNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5288182 pEC50 39.81 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCCOC3)c2n1 CHEMBL5270237 pEC50 39.81 nM
CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCC3CCOCC3)c2n1 CHEMBL5280438 pEC50 39.81 nM
CCCCNc1nc(N)nc2ccn(Cc3cn4ccccc4n3)c12 CHEMBL4069769 EC50 40.0 nM
CC(Nc1nc(N)nc2ccn(Cc3ccccn3)c12)c1ccccn1 CHEMBL4100122 EC50 40.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4ncccc4Cl)c23)no1 CHEMBL4080513 EC50 40.0 nM
COCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3)nc12 CHEMBL5085705 EC50 40.0 nM
CCOC(=O)COc1cc(F)cc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5275611 EC50 40.3 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NCC(=O)N(C)C)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5435544 IC50 41.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OC(C)C(=O)OC)c1 CHEMBL5280107 EC50 42.6 nM
CCOC(=O)COc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)NCCN(C)C)c1 CHEMBL5272563 EC50 42.9 nM
Nc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL2024167 Activity 43.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)c4cccnc34)c12 CHEMBL5434111 EC50 44.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CN4CC5CC4CN5)cc3OC)c12 CHEMBL5399638 EC50 44.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CNC(=O)OC(C)(C)C)cc1 CHEMBL5424404 EC50 44.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CNCC(N)=O)cc1OC CHEMBL5283440 pEC50 44.67 nM
Cn1ncc2c(-c3ccc(OCC45CCC(N)(CC4)CC5)c(F)c3)nc(N)nc21 CHEMBL4740820 IC50 45.0 nM
COCCN1CCN(c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 CHEMBL1837072 EC50 45.8 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccc(C)c(OCC(=O)OC(C)C)c1 CHEMBL5281367 EC50 45.8 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCOCC1 CHEMBL4090816 EC50 46.0 nM
Cc1cc(-c2ccc(OCC34CCC(N)(CC3)CC4)c(F)c2)c2cnc(N)nn12 CHEMBL4792072 IC50 46.0 nM
CCOC(=O)C(C)(C)Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5269286 EC50 46.4 nM
COCCCN1CCN(c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 CHEMBL1837071 EC50 47.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)c(OC)c3)nc12 CHEMBL5079288 EC50 47.0 nM
CCOC(=O)COc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)NCCN2CCCCC2)c1 CHEMBL5271968 EC50 47.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4=CC5(CCN(C6CCOCC6)CC5)C4)cc3OC)c12 CHEMBL5414529 EC50 48.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCNCC4)nc3)c2n1 CHEMBL2315167 EC50 48.5 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(CCO)CC4)cc3OC)c12 CHEMBL5418809 EC50 49.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OCC(C)C)c1 CHEMBL5270161 EC50 49.9 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1760437 EC50 50.0 nM
Nc1nc2ccccc2c2c1nc(CCCc1nc3c(N)nc4ccccc4c3n1Cc1ccccc1)n2Cc1ccccc1 CHEMBL2018888 IC50 50.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OC(=O)CN CHEMBL3921751 EC50 50.0 nM
CCC(O)CNc1nc(N)nc2ccn(Cc3ccccn3)c12 CHEMBL4092365 EC50 50.0 nM
COCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCCC4)cc3)nc12 CHEMBL5087987 EC50 50.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(CC(=O)OC)c3)c2n1 CHEMBL1089224 EC50 50.1 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCN(CCOC)CC1 CHEMBL5267013 pEC50 50.12 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCO)cc1OC CHEMBL5279454 pEC50 50.12 nM
CCCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1OC CHEMBL5271512 pEC50 50.12 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1F CHEMBL5280218 pEC50 50.12 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1F CHEMBL5272339 pEC50 50.12 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCCC2)cc1O CHEMBL5273307 pEC50 50.12 nM
CCCCNc1nc(N)nc(C)c1Sc1ccc(CC(=O)OCCCCN2CCCC2)cc1 CHEMBL5281947 pEC50 50.12 nM
CCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1OC CHEMBL5286020 pEC50 50.12 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCC3CCOCC3)c2n1 CHEMBL5281969 pEC50 50.12 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN4CCOCC4)nc3)c2n1 CHEMBL2315162 EC50 50.2 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-n4nccn4)cc32)cn1 CHEMBL1760582 EC50 51.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(C(=O)OC)c3)c2n1 CHEMBL1089863 EC50 51.5 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OC2(C(=O)OC)CC2)c1 CHEMBL5281112 EC50 51.8 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)(C)C)c1 CHEMBL5274813 EC50 52.2 nM
Cn1nc(-c2ccc(OCCCC3CCNCC3)c(F)c2)c2cnc(N)nc21 CHEMBL4755173 IC50 53.0 nM
CCC[C@@H](CO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC)c12 CHEMBL5416423 IC50 53.7 nM
CCOC(=O)COc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5272502 EC50 54.6 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN(C)CC(N)=O)cc1OC CHEMBL5285351 pEC50 54.95 nM
CCOCc1nc2c(N)nc3cc(CCC(=O)OCC)ccc3c2n1CC(C)(C)OC(=O)CN CHEMBL3967031 EC50 55.0 nM
CN1CCN(CC2CCCN2c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 CHEMBL1837073 EC50 55.4 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccc(OC)c(OCC(=O)OC(C)C)c1 CHEMBL5283934 EC50 55.8 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(C5CCN(C)CC5)CC4)cc3OC)c12 CHEMBL5403684 EC50 56.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCN(C)C(=O)C5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5402315 IC50 56.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC2CCC2)c1 CHEMBL5269918 EC50 56.1 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(CCN(C)C)Cc1cccc(OCC(=O)OC(C)(C)C)c1 CHEMBL5272783 EC50 56.4 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC2CCCC2)c1 CHEMBL5269610 EC50 56.6 nM
CCc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 CHEMBL5186413 IC50 57.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(Cc1ccc(F)c(OCC(=O)OC(C)C)c1)C(=O)NCCN1CCCCC1 CHEMBL5290083 EC50 57.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCOCC4)cc3)c2n1 CHEMBL2315154 EC50 58.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCOCC4)cc3)nc12 CHEMBL5083597 EC50 58.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNC2CC3(CNC3)C2)cc1 CHEMBL5398942 EC50 58.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CNC4CCC4)cc3OC)c12 CHEMBL5413224 EC50 58.0 nM
CCCCC(=O)Nc1ccc(Cn2c(CCCC)nc3c(N)nc4ccccc4c32)cc1 CHEMBL5396405 EC50 59.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1086473 EC50 59.1 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN CHEMBL3904306 EC50 60.0 nM
CCCCNc1nc(N)nc2ccn(CCOc3ccccc3)c12 CHEMBL4075866 EC50 60.0 nM
CCCCNc1nc(N)nc2ccn(CCCc3ccccc3)c12 CHEMBL4085732 EC50 60.0 nM
CCCCNc1nc(N)nc2ccn(Cc3ccccn3)c12 CHEMBL4096964 EC50 60.0 nM
Cc1cc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)no1 CHEMBL4103847 EC50 61.0 nM
CCCCOC(=O)COc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1 CHEMBL5278058 EC50 61.3 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCCCNC(=O)OC(C)(C)C)cc1 CHEMBL5419915 EC50 62.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)CCOC CHEMBL5279830 pEC50 63.1 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCC1 CHEMBL5267292 pEC50 63.1 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1O CHEMBL5281048 pEC50 63.1 nM
CCCCNc1nc(N)nc(C)c1Sc1ccc(CC(=O)OCC2CCN(C)CC2)cc1 CHEMBL5270457 pEC50 63.1 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CN2CCNCC2)cc1OC CHEMBL5287564 pEC50 63.1 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCC3CCOCC3)c2n1 CHEMBL5278428 pEC50 63.1 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCOC3)c2n1 CHEMBL5281030 pEC50 63.1 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1 CHEMBL150961 EC50 63.7 nM
Cc1cc(OCCCP(=O)(O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1 CHEMBL3828331 EC50 65.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(OCCN(C)C)cc3)nc12 CHEMBL5079616 EC50 66.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1 CHEMBL5268173 EC50 66.1 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OC)c1)C(=O)CN(CC)CC CHEMBL5284794 EC50 67.7 nM
CCN(C)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1 CHEMBL5273257 EC50 67.8 nM
CCOC(=O)C1(Oc2cccc(CN(CCCn3c(CCOC)nc4c(N)nc5ccccc5c43)C(=O)CN(CC)CC)c2)CCC1 CHEMBL5288639 EC50 69.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(N)cc1 CHEMBL5423654 EC50 69.0 nM
Cc1ccc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)nc1 CHEMBL4082112 EC50 70.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccc(OC)c(OC)c4)c(CC(F)(F)F)c3c2)CC1 CHEMBL4637139 IC50 70.0 nM
CCCCNc1nc(N)nc2ccc(Cc3cccc(CN(C)C)c3)nc12 CHEMBL5076212 EC50 70.0 nM
Cn1nc(-c2ccc(OC[C@H]3CC[C@@H](N)CC3)c(F)c2)c2cnc(N)nc21 CHEMBL4782200 IC50 71.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)N(C)C)cc3)nc12 CHEMBL5071236 EC50 71.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N(C)CCCN(C)C)nc3)c2n1 CHEMBL2315163 EC50 72.8 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccc(C(=O)OC)cc3)c2n1 CHEMBL1090529 EC50 72.9 nM
CCCCc1nc2c(N)nc3cc(O)ccc3c2n1CC(C)C CHEMBL4646933 EC50 73.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN(CC)CC CHEMBL5273836 EC50 73.6 nM
CCOC(=O)COc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1F CHEMBL5284039 EC50 73.9 nM
COc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL2024166 Activity 74.0 nM
COc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5194452 IC50 74.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(C(C)C(=O)OC)c3)c2n1 CHEMBL1089226 EC50 75.0 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(C(F)(F)F)nc1 CHEMBL2024165 Activity 75.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O CHEMBL383322 EC50 75.0 nM
CCCCc1nc2c(N)nc(NCc3ccc(OC)cc3)cc2n1Cc1ccccc1 CHEMBL5272402 EC50 75.0 nM
CCCCc1nc2c(N)nc(NCc3ccco3)cc2n1Cc1ccccc1 CHEMBL5269245 EC50 75.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN[C@H](CO)Cc2ccccc2)cc1 CHEMBL5407889 EC50 76.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccc(F)c(OCC(=O)OC(C)C)c1 CHEMBL5267422 EC50 77.4 nM
Cc1nc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cs1 CHEMBL1760444 EC50 79.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC(F)F)c12 CHEMBL5439307 EC50 79.0 nM
CCOC(=O)COc1cc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)NCCN2CCCCC2)ccc1F CHEMBL5281949 EC50 79.1 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)C CHEMBL5271280 pEC50 79.43 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCCC1 CHEMBL5277514 pEC50 79.43 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN(CCC)CCC CHEMBL5287218 pEC50 79.43 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCCC1 CHEMBL5265877 pEC50 79.43 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCN(C)CC1 CHEMBL5275298 pEC50 79.43 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCCCC1 CHEMBL5276572 pEC50 79.43 nM
CCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1O CHEMBL5288941 pEC50 79.43 nM
CCCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1OC CHEMBL5274202 pEC50 79.43 nM
COCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCOCC4)cc3)nc12 CHEMBL5073114 EC50 80.0 nM
CCCCc1nc2c(N)nc3cc(OC)ccc3c2n1CC(C)(C)O CHEMBL4642293 EC50 81.0 nM
CC(C)c1c(-c2ccnc(CO)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5196314 IC50 81.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1OC CHEMBL5287409 EC50 81.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CNCCC(N)=O)cc1OC CHEMBL5273802 pEC50 81.28 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccnc(OCCN2CCCC2)c1 CHEMBL1837069 EC50 81.9 nM
CCN(C)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OC(C)(C)C(=O)OC)c1 CHEMBL5281420 EC50 82.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1cccc(CN)c1 CHEMBL5414658 EC50 82.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4=CC5(CCN(C(C)C)CC5)C4)cc3OC)c12 CHEMBL5411647 EC50 82.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(C)C CHEMBL5291193 EC50 83.4 nM
CCCCc1nc2c(N)nc3cc(Cl)ccc3c2n1CC(C)(C)O CHEMBL4638690 EC50 84.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ncc(C4CCNCC4)cc3OC)c12 CHEMBL5398842 EC50 84.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)OCC)cc1 CHEMBL5424893 EC50 84.0 nM
CCOC(=O)COc1cc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)ccc1OC CHEMBL5286167 EC50 84.2 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccc(OCC(=O)OC)cc1 CHEMBL5281073 EC50 84.5 nM
CCOC(=O)C(C)(C)Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(C)CC)c1 CHEMBL5267142 EC50 84.6 nM
CC[S@@](=N)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(Cl)cc3)c2n1 CHEMBL5397718 EC50 85.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OCC)c1)C(=O)CN(CC)CC CHEMBL5265869 EC50 86.1 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-c4nc(C)co4)cc32)cn1 CHEMBL1760581 EC50 87.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(C4CCNCC4)cc3OC(F)F)c12 CHEMBL5427884 EC50 87.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(CCC(=O)OC)c3)c2n1 CHEMBL1089548 EC50 87.5 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(CCCN1CCOCC1)Cc1cccc(OC(C)(C)C(=O)OC)c1 CHEMBL5272702 EC50 87.7 nM
CCCCc1nc2c(N)nc3ccsc3c2n1CCCCCN CHEMBL5421674 EC50 89.0 nM
COc1ccc(CCc2cnc3c(N)nc4cc(CCP(=O)(O)O)ccc4c3c2)c(C)c1 CHEMBL3827413 EC50 90.0 nM
Cc1nnc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)o1 CHEMBL4061921 EC50 90.0 nM
CCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1086474 EC50 91.5 nM
CC(C)c1c(-c2ccnc(C3CC3)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5175964 IC50 92.0 nM
CCOC(=O)COc1cc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)ccc1F CHEMBL5276724 EC50 93.2 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)nc1 CHEMBL1760438 EC50 95.0 nM
Cn1nc(-c2ccc(OCC3C[C@H]4CC[C@@H](C3)N4)c(F)c2)c2cnc(N)nc21 CHEMBL4796453 IC50 95.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)N4CCCC4)cc3)nc12 CHEMBL5088082 EC50 95.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CNCCO)cc1OC CHEMBL5285042 pEC50 95.5 nM
CCOC(=O)COc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(CC)CC)c1OC CHEMBL5266199 EC50 95.7 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OCC)c1)C(=O)CN(CC)CC CHEMBL5269413 EC50 96.4 nM
Cc1cnccc1-c1[nH]c2ccc(C3CCNCC3)cc2c1C(C)C CHEMBL5179724 IC50 97.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CNC4COC4)cc3OC)c12 CHEMBL5409254 EC50 97.0 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(OCC4CCOCC4)cc32)cn1 CHEMBL1760587 EC50 99.0 nM
Cc1cnc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)s1 CHEMBL4096097 EC50 99.0 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-c4nccs4)cc32)cn1 CHEMBL519685 EC50 100.0 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-c4ncco4)cc32)cn1 CHEMBL1760580 EC50 100.0 nM
COCCOc1nc(N)c2[nH]c(=O)c(=O)n(Cc3cccc(CN4CCCC4)c3)c2n1 CHEMBL2426788 MEC 100.0 nM
CCCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2424762 MEC 100.0 nM
CCCCSc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2424765 MEC 100.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1ccccc1CN1CCCC1)CC(=O)N2 CHEMBL2424776 MEC 100.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCC3CCNCC3)c2n1 CHEMBL3398488 EC50 100.0 nM
CCCCNc1nc(N)nc2ccn(Cc3ccccc3)c12 CHEMBL4072020 EC50 100.0 nM
Cc1cnc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)o1 CHEMBL4079597 EC50 100.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCCC1 CHEMBL5281850 pEC50 100.0 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCCC2)cc1 CHEMBL5285439 pEC50 100.0 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN(C)C)cc1O CHEMBL5276291 pEC50 100.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1O CHEMBL5289741 pEC50 100.0 nM
CCCCCNc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1O CHEMBL5280117 pEC50 100.0 nM
CCCCOc1nc(N)c2[nH]cc(Cc3ccc(CN4CCCC4)cc3)c2n1 CHEMBL5268440 EC50 100.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCOCC3)c2n1 CHEMBL5280063 pEC50 100.0 nM
CCCCOc1nc(N)c2c(n1)C(CC[C@@H]1CCOC1)C(=O)N2 CHEMBL5288608 pEC50 100.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(CC)CC CHEMBL5290305 EC50 100.3 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccccc1 CHEMBL1760434 EC50 102.0 nM
Cc1cc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)no1 CHEMBL1760443 EC50 103.0 nM
COCCNc1cc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)ccn1 CHEMBL1837070 EC50 105.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(C)CC CHEMBL5267507 EC50 105.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(C)=O)cc1 CHEMBL5433548 EC50 107.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cc(CC(=O)OC)ccc3OC)c2n1 CHEMBL1092655 EC50 108.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=S)NCCCCCNC(=O)COc2ccc(C3=[N+]4C(=Cc5ccc(-c6cccs6)n5[B-]4(F)F)C=C3)cc2)cc1 CHEMBL1269159 EC50 108.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(CN)c1 CHEMBL1271705 EC50 110.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=O)CCCCC(=O)NCc2ccc(Cn3c(CCCC)nc4c(N)nc5ccccc5c43)cc2)cc1 CHEMBL2018887 IC50 110.0 nM
CCCCc1nc2c(N)nc3cc(OC)ccc3c2n1CC(C)C CHEMBL4642612 EC50 110.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccccc3CN(C)C)nc12 CHEMBL5091330 EC50 110.0 nM
CCOC(=O)C(C)(C)Oc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)CCCN2CCOCC2)c1 CHEMBL5282614 EC50 111.5 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(CCCN1CCOCC1)Cc1cccc(OCC(=O)OC(C)(C)C)c1 CHEMBL5271332 EC50 114.5 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC2CCOCC2)c1 CHEMBL5271960 EC50 114.7 nM
CCOC(=O)C(C)(C)Oc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(C)C)c1 CHEMBL5281375 EC50 114.9 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=S)Nc2ccc(-c3c4ccc(=[N+](CC)CC)cc-4oc4cc(N(CC)CC)ccc34)c(C(=O)O)c2)cc1 CHEMBL1269158 EC50 115.0 nM
CCc1coc(-c2cc3c([nH]c(=O)n3Cc3ccc(C)nc3)c(N)n2)n1 CHEMBL2024169 Activity 116.0 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1cccnc1OCCN1CCCC1 CHEMBL1837063 EC50 121.0 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCCO)nc1 CHEMBL1836894 EC50 121.0 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCC2CC2)nc1 CHEMBL2024168 Activity 122.0 nM
CCN(C)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC2CCCC2)c1 CHEMBL5267311 EC50 122.9 nM
COCCNc1ncccc1Cn1c(=O)[nH]c2c(N)nc(C(F)(F)F)cc21 CHEMBL1837064 EC50 125.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(C)=O CHEMBL5276073 pEC50 125.89 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN(C)CCCC CHEMBL5290803 pEC50 125.89 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN(C)C1CCOCC1 CHEMBL5281551 pEC50 125.89 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1 CHEMBL5274601 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC(C)(C)CN(C)C)cc1 CHEMBL5271291 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN(C)C)cc1 CHEMBL5278002 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC2CCN(C)CC2)cc1 CHEMBL5278735 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCN2CCOCC2)cc1 CHEMBL5287810 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCCC2)cc1 CHEMBL5290490 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCN(C)C)cc1 CHEMBL5284679 pEC50 125.89 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCN2CCN(C)CC2)cc1 CHEMBL5287184 pEC50 125.89 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1O CHEMBL5265921 pEC50 125.89 nM
CCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCCC2)cc1O CHEMBL5277722 pEC50 125.89 nM
CCCCOc1nc(N)c2c(n1)C(CC[C@H]1CCOC1)C(=O)N2 CHEMBL5268422 pEC50 125.89 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC2CCCC2)c1)C(=O)CN(C)C CHEMBL5274087 EC50 128.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3cccc(N4CCN(C)CC4)c3)c2n1 CHEMBL2315157 EC50 130.0 nM
CCOCc1nc2c(N)nc3cc(Br)ccc3c2n1CC(C)(C)OCCN CHEMBL3960305 EC50 130.0 nM
CCCCNc1nc(N)nc2ccn(Cc3nccs3)c12 CHEMBL4066900 EC50 130.0 nM
Nc1nc(NCc2ncco2)c2c(ccn2Cc2ccccn2)n1 CHEMBL4097707 EC50 130.0 nM
Cc1cc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)on1 CHEMBL4095383 EC50 130.0 nM
CCc1c(-c2ccc(OC)c(OC)c2)[nH]c2ccc(C3CCN(CCNC)CC3)cc12 CHEMBL4637254 IC50 130.0 nM
CCOC(=O)COc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)NCCCN2CCCCC2)c1 CHEMBL5270899 EC50 130.1 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCC5(CC4)CNC5)cc3OC)c12 CHEMBL5417342 EC50 133.0 nM
CCOCc1nc2c(N)nc3cc(CCC(=O)OCC)ccc3c2n1CC(C)(C)OCCN CHEMBL3984333 EC50 134.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CC5(C4)CN(C(C)C)C5)cc3OC)c12 CHEMBL5427789 EC50 134.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN1CCCCC1 CHEMBL5266081 EC50 135.1 nM
CCCCNc1nc(N)nc2ccc(CCc3ccc(CN(C)C)cc3)nc12 CHEMBL5080899 EC50 136.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN1CCCC1 CHEMBL5281346 EC50 136.2 nM
CCOC(=O)COc1ccccc1CN(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)C(=O)CN(CC)CC CHEMBL5267974 EC50 136.6 nM
CCOCc1nc2c(N)nc3cc(/C=C/C(=O)OCC)ccc3c2n1CC(C)(C)OCCN CHEMBL3975333 EC50 139.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(C)C CHEMBL5290635 EC50 139.2 nM
CCCCNc1nc(N)nc(C)c1CCCn1ccc2ccccc21 CHEMBL4065927 EC50 140.0 nM
CCCCNc1nc(N)nc2ccn(Cc3ncc(C)c(OC)c3C)c12 CHEMBL4080468 EC50 140.0 nM
Cc1cc(-c2ccc(=O)n(C)c2)cc2cn(C3CCNCC3)nc12 CHEMBL4639145 IC50 140.0 nM
COCCOc1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2n1 CHEMBL210884 EC50 140.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CN4CCOCC4)cc3OC)c12 CHEMBL5440967 EC50 140.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(CC#N)CC4)cc3OC)c12 CHEMBL5430110 EC50 145.0 nM
CCOC(=O)COc1ccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN2CCCC2)cc1 CHEMBL5287206 EC50 149.6 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCC3CCNCC3)c2n1 CHEMBL3398485 EC50 150.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCNCC3)c2n1 CHEMBL3398487 EC50 150.0 nM
COc1ccc(CCc2cnc3c(N)nc4cc(/C=C/P(=O)(O)O)ccc4c3c2)c(C)c1 CHEMBL3828519 EC50 150.0 nM
Cc1coc(CNc2nc(N)nc3ccn(Cc4ccccn4)c23)n1 CHEMBL4065786 EC50 150.0 nM
CCCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN CHEMBL3959973 EC50 152.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CNC2CN(C)C2)cc1OC CHEMBL5271443 pEC50 154.88 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OC)c1)C(=O)CN1CCCC1 CHEMBL5284200 EC50 155.5 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(COC)cc3)nc12 CHEMBL5090751 EC50 156.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)N4CCOCC4)cc3)nc12 CHEMBL5073954 EC50 156.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1F)C(=O)CN(CC)CC CHEMBL5268126 EC50 158.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(CC(=O)OC)c1)C(=O)CN1CCCCC1 CHEMBL5276800 pEC50 158.49 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CCN(C)C CHEMBL5285170 pEC50 158.49 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)CCOC CHEMBL5282455 pEC50 158.49 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCOCC1 CHEMBL5290562 pEC50 158.49 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(CCOC)CC1 CHEMBL5290367 pEC50 158.49 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN(C)CC)Cc1cccc(C(=O)OC)c1 CHEMBL5283299 pEC50 158.49 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN(C)CCOC CHEMBL5288012 pEC50 158.49 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCN(C)CC2)cc1 CHEMBL5275375 pEC50 158.49 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCC2CCN(C)CC2)cc1 CHEMBL5288761 pEC50 158.49 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1 CHEMBL5267376 pEC50 158.49 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCCO3)c2n1 CHEMBL5284286 pEC50 158.49 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC)c12 CHEMBL5401895 EC50 159.0 nM
CCCCOc1nc(N)c2nc(O)n(Cc3ccc(C(=O)NCCCCCC(=O)Oc4ccc(/C=C/C(=O)NCC(=O)N[C@H](C(=O)N[C@H](CCC(=O)OCC)C(=O)OCC)C(C)C)cc4OC)cc3)c2n1 CHEMBL5178827 EC50 161.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCNCC4)cc3OC)c12 CHEMBL5419694 EC50 163.0 nM
CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCNC)nc3)c2n1 CHEMBL2315161 EC50 165.7 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OCC)c1)C(=O)CN1CCCC1 CHEMBL5269862 EC50 165.9 nM
CCCCNc1nc(N)c2nc(O)n(Cc3ccc(C)cc3)c2n1 CHEMBL438447 EC50 166.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)OC(C)C)cc1 CHEMBL5436292 EC50 168.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OC)c1)C(=O)CN(C)C CHEMBL5268896 EC50 168.1 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(OCC(=O)OC)cc1)C(=O)CN1CCCCC1 CHEMBL5278820 EC50 168.9 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=O)CCCCCCCCCCC(=O)NCc2ccc(Cn3c(CCCC)nc4c(N)nc5ccccc5c43)cc2)cc1 CHEMBL2018897 IC50 170.0 nM
Cn1nc(-c2ccc(OCC3CCNCC3)c(F)c2)c2cnc(N)nc21 CHEMBL4776103 IC50 170.0 nM
CCCCNc1nc(N)nnc1OCc1ccccn1 CHEMBL5273911 EC50 170.0 nM
CCOC(=O)COc1ccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(C)C)cc1 CHEMBL5281238 EC50 172.3 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(C)CCOC CHEMBL5267141 EC50 172.9 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OC)c1)C(=O)CN(CC)CC CHEMBL5277219 EC50 173.7 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OCCOC)c1 CHEMBL5288396 EC50 174.3 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCCCCNC(=O)OC(C)(C)C)cc1 CHEMBL5408883 EC50 176.0 nM
CCOC(=O)COc1ccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN2CCCCC2)cc1 CHEMBL5284004 EC50 177.3 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN1CCCCC1 CHEMBL5272344 EC50 178.4 nM
CCCCc1nc2c(N)nc3cc(C(=O)OC)ccc3c2n1Cc1ccc(CN)cc1 CHEMBL4170901 EC50 180.0 nM
NCc1ccc(Cn2c(CC3CC3)nc3c(N)nc4ccccc4c32)cc1 CHEMBL5188189 EC50 180.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCNCc1cccc(OCC(=O)OC)c1 CHEMBL5269759 EC50 181.3 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OC)c1)C(=O)CN(C)C CHEMBL5266448 EC50 181.3 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1C CHEMBL5280384 EC50 183.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(CC(=O)OCC)c3)c2n1 CHEMBL1093467 EC50 187.9 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1nc(CN)cs1 CHEMBL5395202 EC50 190.0 nM
CCCCn1cc2c(n1)c(N)nc1ccccc12 CHEMBL5400758 EC50 190.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN(C)C CHEMBL5279460 EC50 191.6 nM
Cc1nc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)co1 CHEMBL1760445 EC50 193.0 nM
CCCCNc1nc(N)nc(C)c1CCCc1ccccc1 CHEMBL4103710 EC50 194.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCNC(=O)CCCCCNC(=O)OC(C)(C)C CHEMBL3944005 EC50 195.0 nM
CCC[C@@H](CCNC(C)=O)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC)c12 CHEMBL5437820 IC50 197.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(N)c1 CHEMBL5393892 EC50 199.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)C CHEMBL5283112 pEC50 199.53 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCC[C@H]1COC CHEMBL5289259 pEC50 199.53 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCC[C@@H]1COC CHEMBL5290030 pEC50 199.53 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(CCOC)CC1 CHEMBL5266035 pEC50 199.53 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCC(NC(=O)OC(C)(C)C)CC1 CHEMBL5268976 pEC50 199.53 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCC(C(=O)OC)CC1 CHEMBL5279760 pEC50 199.53 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCC(OC)CC1 CHEMBL5274329 pEC50 199.53 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1 CHEMBL5272945 pEC50 199.53 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(CCOC)CC2)cc1 CHEMBL5273269 pEC50 199.53 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1 CHEMBL5286938 pEC50 199.53 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN(C)C)cc1F CHEMBL5275268 pEC50 199.53 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CC3CCOCC3)c2n1 CHEMBL5269499 pEC50 199.53 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCC3CCOCC3)c2n1 CHEMBL5270791 pEC50 199.53 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCN3CCOCC3)c2n1 CHEMBL5271980 pEC50 199.53 nM
COc1ccc(CCc2cnc3c(N)nc4cc(/C=C(\F)P(=O)(O)O)ccc4c3c2)c(C)c1 CHEMBL3828701 EC50 200.0 nM
Cn1nc(-c2ccc(OCC34CCC(O)(CC3)CC4)c(F)c2)c2cnc(N)nc21 CHEMBL4745239 IC50 200.0 nM
CC(C)c1c(-c2ccncc2CO)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5204983 IC50 200.0 nM
CCCCc1nc2c(N)nc3sccc3c2n1Cc1ccc(CN)cc1 CHEMBL5399731 EC50 200.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCCN(Cc1ccc(F)c(OCC(=O)OC)c1)C(=O)NCCN1CCCCC1 CHEMBL5289426 EC50 201.3 nM
CCOC(=O)COc1cccc(CN(CCCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)NCCCN(C)C)c1 CHEMBL5278269 EC50 203.7 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(CNC4CCOCC4)cc3OC)c12 CHEMBL5425931 EC50 204.0 nM
C#CCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082642 EC50 209.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CN)cc1 CHEMBL5434429 EC50 209.0 nM
CC(C)Cc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CN)cc1 CHEMBL5190012 EC50 210.0 nM
CCCCc1nc2c(N)nc(NCc3ccccc3)cc2n1Cc1ccccc1 CHEMBL5280727 EC50 210.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccc(OC)c(OCC(=O)OC)c1 CHEMBL5291413 EC50 211.9 nM
CCCCNc1nc(N)nc2ccn(CC=C(C)C)c12 CHEMBL4077873 EC50 220.0 nM
COc1cc2c(C(=O)N3CCN(C)CC3)n[nH]c2cc1-c1ccncc1 CHEMBL5081397 IC50 220.0 nM
CCCCc1nc2c(N)nc3cc4ccccc4cc3c2n1Cc1ccccc1 CHEMBL5283930 EC50 220.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCNC(=O)c1cccnc1 CHEMBL3942013 EC50 223.0 nM
CCN(C)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1cccc(OCC(=O)OC(C)C)c1F CHEMBL5285686 EC50 227.5 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCCC3CCNCC3)c2n1 CHEMBL3398489 EC50 230.0 nM
Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCCP(=O)(O)O)cc3C)cc12 CHEMBL3827244 EC50 230.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(O)c1 CHEMBL5414036 EC50 231.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(OC)cc1 CHEMBL5400489 EC50 232.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OCC)c1)C(=O)CN(C)C CHEMBL5280737 EC50 235.2 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=O)CCCCCCC(=O)NCc2ccc(Cn3c(CCCC)nc4c(N)nc5ccccc5c43)cc2)cc1 CHEMBL2018896 IC50 240.0 nM
Cc1cc(OCCCC(F)(F)P(=O)(O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1 CHEMBL3827669 EC50 240.0 nM
CCC[C@H](C)Oc1nc(N)c2[nH]c(=O)n(CCCCCC3CCNCC3)c2n1 CHEMBL4644453 EC50 240.0 nM
CCC[C@H](CCO)Nc1nc(N)nnc1OCc1nccc(OC)c1OC CHEMBL5280595 EC50 240.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccccc1OCC(=O)OC CHEMBL5269882 EC50 243.4 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=S)Nc2cccc(-c3c4ccc(=O)cc-4oc4cc(O)ccc34)c2C(=O)O)cc1 CHEMBL1269157 EC50 247.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(OCC(=O)OC)cc1)C(=O)CN(C)C CHEMBL5284156 EC50 247.1 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccc(OC)c(OC)c4)c(C)c3c2)CC1 CHEMBL4647818 IC50 250.0 nM
CCCCc1nc2c(N)nc(NCc3ccncc3)cc2n1Cc1ccccc1 CHEMBL5286152 EC50 250.0 nM
CCCCc1nc2c(N)nc(NCc3cccnc3)cc2n1Cc1ccccc1 CHEMBL5276081 EC50 250.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCN(C)CC1 CHEMBL4071479 EC50 251.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCN(C)C)Cc1ccc(CC(=O)OC)cc1 CHEMBL5279651 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(C(C)=O)CC1 CHEMBL5277994 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CC[C@@H](O)C1 CHEMBL5283564 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(S(=O)(=O)CC)CC1 CHEMBL5279324 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN(C)C)Cc1cccc(C(=O)OC)c1 CHEMBL5268559 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCC1 CHEMBL5279270 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN1CCOCC1)Cc1cccc(C(=O)OC)c1 CHEMBL5291177 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN1CCN(C)CC1)Cc1cccc(C(=O)OC)c1 CHEMBL5268789 pEC50 251.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCN(C)CC1 CHEMBL5288112 pEC50 251.19 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCN2CCN(C)CC2)cc1 CHEMBL5290333 pEC50 251.19 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCN(C)C)cc1 CHEMBL5280114 pEC50 251.19 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCN2CCOCC2)cc1 CHEMBL5277908 pEC50 251.19 nM
COc1ccc(-c2nc3cc(N4CCN(C(C)C)CC4)ccn3c2CN2CCCC2)c(OC)c1 CHEMBL5176310 IC50 258.0 nM
CCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(CC)CC CHEMBL5281712 EC50 259.9 nM
CCCCNc1nc(N)nc2ccn(Cc3cccnc3)c12 CHEMBL4075398 EC50 260.0 nM
O=C(NNC(=O)c1csc(-c2ccc(Cl)cc2Cl)n1)c1ccccn1 CHEMBL4213787 IC50 260.0 nM
CCCCc1nc2c(N)nc(NCc3ccc(CN)cc3)cc2n1Cc1ccccc1 CHEMBL5276534 EC50 260.0 nM
CCCCc1nc2c(N)nc3cc(-c4ccccc4)sc3c2n1Cc1ccc(CN)cc1 CHEMBL5432634 EC50 260.0 nM
C=CCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082399 EC50 262.0 nM
CCCCNc1nc(N)nc(C)c1CCCCc1ccccc1 CHEMBL4085784 EC50 262.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN(CC)CC CHEMBL5284026 EC50 262.1 nM
CCCCNc1nc(N)nc(C)c1CCCCCc1ccccc1 CHEMBL4095966 EC50 265.0 nM
Cc1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2c1C CHEMBL3221819 EC50 266.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CNC(=S)NCC(=O)NCC(=O)NCC(=O)OC)cc1 CHEMBL1778421 EC50 269.0 nM
CCCC[C@@H](CCO)Nc1nc(N)nc(CCC(=O)O)c1Cc1cc(Cc2nn[nH]n2)ccc1OC CHEMBL5406749 EC50 270.0 nM
CCC[C@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(C5CCOCC5)CC4)cc3OC)c12 CHEMBL5427518 EC50 272.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(O)cc1 CHEMBL5406767 EC50 275.0 nM
CCN(CC)CC(=O)N(CCCn1c(CCOC)nc2c(N)nc3ccccc3c21)Cc1ccc(F)c(OCC(=O)OC)c1 CHEMBL5273493 EC50 278.2 nM
CCCCNc1nc(N)nc2ccn(Cc3ccc4ccccc4n3)c12 CHEMBL4063409 EC50 280.0 nM
CCCCc1cc2c(nc(CCCC)n2Cc2ccccc2)c(N)n1 CHEMBL5271814 EC50 280.0 nM
CCCCc1nc2c(N)nc(Cc3ccccc3)cc2n1Cc1ccccc1 CHEMBL5268151 EC50 280.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(CN4CC5(CNC5)C4)cc3OC)c12 CHEMBL5435487 EC50 293.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1F)C(=O)CN(C)C CHEMBL5272247 EC50 296.6 nM
CCCCOc1cc2c(c(N)n1)NC(=O)CN2Cc1cccc(CN2CCCC2)c1 CHEMBL2426785 MEC 300.0 nM
CCCCOc1nc(N)c2c(n1)N1Cc3cccc(CN4CCCC4)c3CC1C(=O)N2 CHEMBL2426794 MEC 300.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)C(C)C(=O)N2 CHEMBL2426796 MEC 300.0 nM
CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCOCC3)c1)CC(=O)N2 CHEMBL2424775 MEC 300.0 nM
CCCCc1nc2c(N)nc3cc(Cl)ccc3c2n1CC(C)C CHEMBL4644843 EC50 300.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CO)cc3)nc12 CHEMBL5091071 EC50 300.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3)cc12 CHEMBL5080244 EC50 300.0 nM
Cc1nc(C)c(C)c(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c1C CHEMBL5205027 IC50 300.0 nM
CC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3OC)c12 CHEMBL5398234 IC50 302.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1F)C(=O)CN(C)C CHEMBL5286082 EC50 303.8 nM
CC(C)c1cc2c([nH]c(=O)n2Cc2ccccc2)c(N)n1 CHEMBL3221826 EC50 304.0 nM
COc1ccc(-c2cn3ccc(N4CCNCC4)cc3n2)c(OC)c1 CHEMBL5193165 IC50 308.0 nM
Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCCC(F)(F)P(=O)(O)O)cc3C)cc12 CHEMBL3828296 EC50 310.0 nM
CN1CCN(CCCOc2ccc(-c3nn(C)c4nc(N)ncc34)cc2F)CC1 CHEMBL4743698 IC50 310.0 nM
COCCOc1nc(N)c2[nH]c(=O)n(Cc3cccc(CC(=O)OC)c3)c2n1 CHEMBL1089517 EC50 312.3 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CCN(C5CCNCC5)CC4)cc3OC)c12 CHEMBL5400486 EC50 315.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN1CCOCC1)Cc1ccc(CC(=O)OC)cc1 CHEMBL5282147 pEC50 316.23 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCNCc1ccc(CC(=O)OC)cc1 CHEMBL5284928 pEC50 316.23 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCC(N(C)C(=O)OC(C)(C)C)CC1 CHEMBL5282525 pEC50 316.23 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C1CCN(C)CC1 CHEMBL5284410 pEC50 316.23 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCOCC2)cc1 CHEMBL5284880 pEC50 316.23 nM
CCCCCNc1nc(N)nc(C)c1Cc1cccc(CC(=O)OCCCCN2CCCC2)c1 CHEMBL5281394 pEC50 316.23 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCC3CCCCO3)c2n1 CHEMBL5266072 pEC50 316.23 nM
CCCCOc1nc(N)c2nc(O)n(CCCN3CCCCC3)c2n1 CHEMBL4446231 pEC50 316.23 nM
CCCCOc1nc(N)c2c(n1)N(C)C(Cc1cccc(CN3CCCC3)c1)C(=O)N2 CHEMBL2426791 MEC 320.0 nM
CCCCCc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 CHEMBL2424764 MEC 320.0 nM
CCCCc1nc2c(N)nc(NCC3CCCCC3)cc2n1Cc1ccccc1 CHEMBL5267775 EC50 320.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3cnc(CNC4CCOCC4)cc3OC)c12 CHEMBL5397470 EC50 321.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN1CCN(C)CC1 CHEMBL5274930 EC50 323.1 nM
Cc1cccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)n1 CHEMBL1760439 EC50 328.0 nM
COc1cc(CNC2CCOCC2)ccc1Cn1ncc2nc(N)nc(N[C@H](CCO)C3CC3)c21 CHEMBL5397705 IC50 333.0 nM
CCCCNc1cc2c(nc(CCCC)n2Cc2ccccc2)c(N)n1 CHEMBL5291110 EC50 340.0 nM
CCCCOC(=O)Cc1ccc(Cn2c(CCCC)nc3c(N)nc4ccccc4c32)cc1 CHEMBL5434936 EC50 344.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN(C)C CHEMBL5266430 EC50 348.7 nM
Cc1cc(OCCOCCOCCP(=O)(O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1 CHEMBL3828229 EC50 350.0 nM
Cc1cnc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1760442 EC50 352.0 nM
Cc1ncc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)cn1 CHEMBL1760441 EC50 366.0 nM
CCCCc1nc2c(N)nc(NCc3cccc(CN)c3)cc2n1Cc1ccccc1 CHEMBL5287022 EC50 370.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CO)cc1 CHEMBL5428234 EC50 370.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CC5(CNC5)C4)cc3OC)c12 CHEMBL5413300 EC50 370.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4CC5(C4)CN(C4CCOCC4)C5)cc3OC)c12 CHEMBL5434082 EC50 370.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1Cc2ccccc2C1 CHEMBL4096879 EC50 375.0 nM
CCCCNc1nc(N)nc(C)c1CCCn1c(C)nc2ccccc21 CHEMBL4093530 EC50 379.0 nM
COc1ccc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C)cc1OC CHEMBL4632877 IC50 380.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CNC2CNC2)cc1OC CHEMBL5283437 pEC50 380.19 nM
CCCCNc1nc(N)nc2cnn(Cc3ccccc3OC)c12 CHEMBL5438107 EC50 384.0 nM
CCNCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082982 EC50 385.0 nM
COc1ccc(CCc2cnc3c(N)nc4cc(C(=O)C(F)(F)P(=O)(O)O)ccc4c3c2)c(C)c1 CHEMBL3828149 EC50 390.0 nM
COc1ccc(-c2cn3ccc(NCCCN4CCCC4)cc3n2)c(OC)c1 CHEMBL5193639 IC50 395.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc2ccccc12 CHEMBL1271653 EC50 396.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(-c2ccccc2)cc1 CHEMBL1271654 EC50 396.0 nM
CCCCNc1nc(N)nc(C)c1CCCn1cccn1 CHEMBL4074552 EC50 398.0 nM
CCCCOc1nc(N)c2nc(O)n(Cc3ccc(C(=O)O)cc3)c2n1 CHEMBL4463682 EC50 398.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCC1 CHEMBL5273687 pEC50 398.11 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(C)CC1 CHEMBL5265810 pEC50 398.11 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CS(C)(=O)=O CHEMBL5283899 pEC50 398.11 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)C1CCN(C(C)=O)CC1 CHEMBL5287685 pEC50 398.11 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCNCc1cccc(C(=O)OC)c1 CHEMBL5273913 pEC50 398.11 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCC(O)C1 CHEMBL5280612 pEC50 398.11 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CC[C@@H](O)C1 CHEMBL5283633 pEC50 398.11 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCOCC1 CHEMBL5268821 pEC50 398.11 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)C CHEMBL5278341 pEC50 398.11 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN(C)CCOC CHEMBL5268181 pEC50 398.11 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1 CHEMBL5288535 pEC50 398.11 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CP(=O)(OCC)OCC)cc3)nc12 CHEMBL5090854 EC50 400.0 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)nn1 CHEMBL1760440 EC50 411.0 nM
Nc1nc(NCc2ccon2)c2c(ccn2Cc2ccccn2)n1 CHEMBL4065280 EC50 420.0 nM
CN(C)[C@@H]1CCN(CCCOc2ccc(-c3nc4ccc(OCCCN5CC[C@@H](N(C)C)C5)cc4o3)cc2)C1 CHEMBL4853223 IC50 430.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC)c1)C(=O)CN1CCN(CCOC)CC1 CHEMBL5280339 EC50 432.5 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1)C(=O)CN1CCCC1 CHEMBL5266529 EC50 433.8 nM
O=C(NNC(=O)c1csc(-c2cc(Cl)cc(Cl)c2)n1)c1ccccn1 CHEMBL4206455 IC50 440.0 nM
CCOC(=O)COc1cccc(CN(CCCn2c(CCOC)nc3c(N)nc4ccccc4c32)C(=O)CN(C)C)c1F CHEMBL5276121 EC50 447.4 nM
CCCCc1nc2c(N)nc3ccc(N)cc3c2n1Cc1ccc(CN)cc1 CHEMBL2018899 IC50 450.0 nM
CCCCOc1nc(N)c2[nH]c(C#N)c(Cc3cnc(CN4CCCC4)s3)c2n1 CHEMBL5279396 EC50 454.0 nM
COc1ccc(-c2cn3ccc(N4CCN(C5CCCC5)CC4)cc3n2)c(OCCCN2CCCC2)c1 CHEMBL5177422 IC50 456.0 nM
c1cc(CN2CCOCC2)ccc1CNCCCOc1ccc2nc(OCCCNCc3ccc(CN4CCOCC4)cc3)oc2c1 CHEMBL4878190 IC50 460.0 nM
CCCCNc1nc(N)nc2c(C3CC3)nn(Cc3ncc(C4CCNCC4)cc3OC)c12 CHEMBL5419165 EC50 461.0 nM
COc1ccc(-c2cn3ccc(N4CCN(C(C)C)CC4)cc3n2)c(OC)c1 CHEMBL5183377 IC50 466.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccccc3CC(=O)OC)c2n1 CHEMBL1089220 EC50 466.8 nM
CCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1083637 EC50 472.0 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(OCC4CCOC4)cc32)cn1 CHEMBL1760586 EC50 474.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OCC(=O)OC(C)C)c1F)C(=O)CN(CC)CC CHEMBL5271557 EC50 474.9 nM
COc1ccc(-c2cn3ccc(N4CCN(C5CCCC5)CC4)cc3n2)c(OCCCN2CCOCC2)c1 CHEMBL5187807 IC50 478.0 nM
CCCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082376 EC50 479.0 nM
CCCc1cc2c([nH]c(=O)n2Cc2ccccc2)c(N)n1 CHEMBL3221827 EC50 480.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCCCCN)cc1 CHEMBL5396643 EC50 485.0 nM
CCCCc1nc2c(NC(=O)CCC)nc3ccccc3c2s1 CHEMBL5282164 EC50 490.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3F)c12 CHEMBL5438543 EC50 495.0 nM
COCCCNc1nc(N)nc2ccn(Cc3ccccn3)c12 CHEMBL4075504 EC50 500.0 nM
CCOCCNc1nc(N)nc2ccn(Cc3ccccn3)c12 CHEMBL4071587 EC50 500.0 nM
O=C(NNC(=O)c1csc(-c2cccc(Cl)c2Cl)n1)c1ccccn1 CHEMBL4218718 IC50 500.0 nM
Cn1nc(-c2ccc(OCC3CC4(CNC4)C3)c(F)c2)c2cnc(N)nc21 CHEMBL4761527 IC50 500.0 nM
CN(C)CCN(C)CCCOc1ccc(-c2nc3ccc(OCCCN(C)CCN(C)C)cc3o2)cc1 CHEMBL4855190 IC50 500.0 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(CC(=O)OC)c1)C(=O)CN1CCN(CCOC)CC1 CHEMBL5282349 pEC50 501.19 nM
COCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(CC(=O)OC)c1)C(=O)CN1CCN(C)CC1 CHEMBL5272761 pEC50 501.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(C)CC1 CHEMBL5279654 pEC50 501.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCN(C(C)=O)CC1 CHEMBL5277954 pEC50 501.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCN(S(C)(=O)=O)CC1 CHEMBL5289456 pEC50 501.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCC(O)CC1 CHEMBL5284074 pEC50 501.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCN(CCO)CC1 CHEMBL5291223 pEC50 501.19 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCN(C(C)=O)CC1 CHEMBL5286290 pEC50 501.19 nM
CCCCCNc1nc(N)nc(C)c1CCCNCc1cccc(CC(=O)OC)c1 CHEMBL5285739 pEC50 501.19 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1F CHEMBL5266886 pEC50 501.19 nM
CCCCCNc1nc(N)nc(C)c1Cc1cccc(CC(=O)OCC2CCN(C)CC2)c1 CHEMBL5265813 pEC50 501.19 nM
CCCCCc1c(C)nc(N)nc1NCCCC CHEMBL4101040 EC50 510.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccnc(OC)c4)c(C)c3c2)CC1 CHEMBL5173429 IC50 520.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OCC)c1)C(=O)CN1CCCC1 CHEMBL5265880 EC50 521.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(OC)c1 CHEMBL5439729 EC50 540.0 nM
CCCCNc1nc(N)nc2c(C)nn(Cc3ncc(C4CCNCC4)cc3OC)c12 CHEMBL5424102 EC50 549.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccncc4)c(C)c3c2)CC1 CHEMBL5189004 IC50 550.0 nM
CCCCc1nc2c(N)nc3ccccc3c2o1 CHEMBL5430530 EC50 550.0 nM
COc1ccc(-c2cn3ccc(N4CCNCC4)cc3n2)cc1 CHEMBL5200947 IC50 559.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(OC(C)(C)C(=O)OC)c1)C(=O)CN1CCCC1 CHEMBL5268934 EC50 559.8 nM
CCCCc1nc2c(N)nc3ccc([N+](=O)[O-])cc3c2n1Cc1ccc(CN)cc1 CHEMBL2018898 IC50 560.0 nM
CCCCc1nc2c(NCCCCCCCCNc3nc4ccccc4c4c3nc(CCCC)n4Cc3ccccc3)nc3ccccc3c2n1Cc1ccccc1 CHEMBL2018893 IC50 560.0 nM
Nc1nc(NCc2nccs2)c2c(ccn2Cc2ccccn2)n1 CHEMBL4103525 EC50 560.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCCC1 CHEMBL4105319 EC50 562.0 nM
CCCC[C@@H](CO)Nc1nc(N)nc2ccccc12 CHEMBL4161854 EC50 570.0 nM
CCCCc1nc2c(N)nc(CCc3ccccc3)cc2n1Cc1ccccc1 CHEMBL5266644 EC50 570.0 nM
CCCCNc1nc(N)nc2c(CC)nn(Cc3ncc(C4CCNCC4)cc3OC)c12 CHEMBL5414156 EC50 572.0 nM
COc1ccc(-c2nc3cc(N4CCN(C5CCCC5)CC4)ccn3c2CN2CCCC2)c(OC)c1 CHEMBL5200138 IC50 580.0 nM
COCCCN1CCN(c2ncccc2Cn2c(=O)[nH]c3c(N)nc(C(F)(F)F)cc32)CC1 CHEMBL1837065 EC50 586.0 nM
CCCCNc1nc(N)nc(C)c1CCCC CHEMBL4103230 EC50 590.0 nM
CCCCc1nc2c(N)nc3cc(C(=O)OC)ccc3c2n1CCCCCN CHEMBL4162974 EC50 600.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(Cc3ccccc3C(=O)OC)c2n1 CHEMBL1089862 EC50 609.1 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccccc4OC)c(F)c3c2)CC1 CHEMBL1614812 IC50 610.0 nM
CCc1c(-c2ccnc(C)c2)[nH]c2c(F)cc(C3CCNCC3)cc12 CHEMBL5191852 IC50 610.0 nM
CCCCc1nc2c(N)nc(NCc3cccc(OC)c3)cc2n1Cc1ccccc1 CHEMBL5284546 EC50 610.0 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCC3CCNCC3)c2n1 CHEMBL3398486 EC50 620.0 nM
CCOCc1nc2c(N)nc3cc(Cl)ccc3c2n1CC(C)(C)O CHEMBL4643293 EC50 630.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccccc3OC)nc12 CHEMBL5093105 EC50 630.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C1CCN(C)CC1 CHEMBL5281942 pEC50 630.96 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(C(=O)OCC)CC1 CHEMBL5290706 pEC50 630.96 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCN(c2ncccn2)CC1 CHEMBL5274588 pEC50 630.96 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCC(C(=O)N(C)C)CC1 CHEMBL5266913 pEC50 630.96 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCCN(S(C)(=O)=O)CC1 CHEMBL5275651 pEC50 630.96 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1cccc(CC(=O)OC)c1)C(=O)CN(C)C CHEMBL5271095 pEC50 630.96 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1cccc(CC(=O)OC)c1)C(=O)CN1CCC[C@@H]1C(=O)OC CHEMBL5283147 pEC50 630.96 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CSC CHEMBL5289214 pEC50 630.96 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCCC1 CHEMBL5283026 pEC50 630.96 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCCCCN2CCC(N(C)C)CC2)cc1 CHEMBL5271034 pEC50 630.96 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1F CHEMBL5266464 pEC50 630.96 nM
CCCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1 CHEMBL5289670 pEC50 630.96 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCN(C)CC2)cc1O CHEMBL5285860 pEC50 630.96 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1cc(CC(=O)OC)ccc1F CHEMBL5268627 pEC50 630.96 nM
Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-n4cccn4)cc32)cn1 CHEMBL1760583 EC50 633.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(OCC(=O)OC)cc1)C(=O)CN1CCN(C)CC1 CHEMBL5279345 EC50 633.1 nM
CCCCc1nc2c(N)nc(NCc3ccc(Cl)cc3)cc2n1Cc1ccccc1 CHEMBL5273642 EC50 640.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(C(=O)NC4CCOCC4)cc3OC)c12 CHEMBL5414135 EC50 644.0 nM
CCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1086143 EC50 647.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccc5c(c4)OCO5)c(C)c3c2)CC1 CHEMBL4643717 IC50 650.0 nM
COc1ccc(-c2cn3ccc(N4CCNCC4)cc3n2)c(OCCCN2CCCC2)c1 CHEMBL5189243 IC50 659.0 nM
CCCCNc1nc(N)nnc1OCc1ccccc1OC CHEMBL5285197 EC50 660.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ncc(C4=CC5(CCNCC5)C4)cc3OC)c12 CHEMBL5427987 EC50 668.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccccc4Cl)c(F)c3c2)CC1 CHEMBL4634971 IC50 690.0 nM
COc1cc2c(N3CCN(CC4CCCC4)CC3)nc(N(C)C)nc2cc1OCCCN1CCCC1 CHEMBL4281194 IC50 700.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCCCCC(=O)O)cc1 CHEMBL5405022 EC50 703.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCCCC1 CHEMBL4061978 EC50 710.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCSCC1 CHEMBL4083025 EC50 714.0 nM
CCCCc1nc2c(NO)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082307 EC50 723.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCCCCC1 CHEMBL4088953 EC50 730.0 nM
COc1ccc(-c2[nH]c3ccc(C4CCN(C5CCN(C)CC5)CC4)cc3c2C)cc1OC CHEMBL4639038 IC50 730.0 nM
CCCCNc1nc(N)nc2ccn(Cc3ccncc3)c12 CHEMBL4091156 EC50 750.0 nM
CCCCNc1nc(N)nnc1OCc1ccccc1F CHEMBL5267126 EC50 750.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CNC)cc3)nc12 CHEMBL5082702 EC50 760.0 nM
CCCCCCCNc1cc2c(nc(CCCC)n2Cc2ccccc2)c(N)n1 CHEMBL5287416 EC50 760.0 nM
CCCCNc1nc(N)nc2cnn(Cc3ccc(N4CCNCC4)cc3OC)c12 CHEMBL5420635 EC50 780.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN1CCOCC1)Cc1cccc(OCC(=O)OC)c1 CHEMBL5284650 EC50 786.6 nM
COCCOc1nc(N)c2nc(NN)n(Cc3ccccc3)c2n1 CHEMBL215536 EC50 790.0 nM
CCCCc1nc2c(N)nc3cc(C#N)ccc3c2n1CC(C)(C)O CHEMBL4643435 EC50 790.0 nM
CNCCCN1CCC(c2ccc3[nH]c(-c4ccc(OC)c(OC)c4)c(C)c3c2)CC1 CHEMBL4641162 IC50 790.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCOCC1 CHEMBL5272068 pEC50 794.33 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1cccc(C(=O)OC)c1)C(=O)CN1CCN(S(C)(=O)=O)CC1 CHEMBL5275920 pEC50 794.33 nM
CCCCCNc1nc(N)nc(C)c1CCCNCc1cccc(OCC(=O)OC)c1 CHEMBL5279724 pEC50 794.33 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CC1CCN(C)CC1 CHEMBL5287036 pEC50 794.33 nM
CCCCCNc1nc(N)nc(C)c1CCCN(Cc1ccc(CC(=O)OC)cc1)C(=O)CN1CCCC(c2ccc(S(C)(=O)=O)cc2)C1 CHEMBL5271935 pEC50 794.33 nM
CCCCCNc1nc(N)nc(C)c1Cc1ccc(CC(=O)OCC2CCNCC2)cc1 CHEMBL5286056 pEC50 794.33 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CC(=O)OC)cc1 CHEMBL5283795 pEC50 794.33 nM
CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCCC3CCOCC3)c2n1 CHEMBL5275665 pEC50 794.33 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(OC)cc3)nc12 CHEMBL5094134 EC50 795.0 nM
CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12 CHEMBL1535 IC50 800.0 nM
CN(C)CCCOc1ccc2nc(-c3ccc(OCCCN(C)CCCN(C)C)cc3)oc2c1 CHEMBL4868741 IC50 800.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc2cnn(Cc3ccc(CNC4CCOCC4)cc3)c12 CHEMBL5416960 EC50 807.0 nM
COc1ccc(-c2cn3ccc(NCCCn4ccnc4)cc3n2)c(OC)c1 CHEMBL5175416 IC50 819.0 nM
COc1ccc(Cn2c(-c3ccccc3)nc3c4ccccc4[n+](Cc4ccc(OC)cc4)cc32)cc1 CHEMBL1795710 IC50 820.0 nM
CCCCCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1086372 EC50 822.0 nM
Cc1nc(N)c2nc(O)n(Cc3ccccc3)c2n1 CHEMBL150245 EC50 829.0 nM
COCCCn1c(=O)[nH]c2c(N)nc(C(F)(F)F)cc21 CHEMBL1760435 EC50 833.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(NC(=O)CCCN)cc1 CHEMBL5433089 EC50 840.0 nM
COc1cc(CNC2CCOCC2)ccc1Cn1ncc2nc(N)nc(N[C@H](CCO)C(C)C)c21 CHEMBL5436496 IC50 849.0 nM
COc1ccc(-c2[nH]c3ccc(C4CCN(CC5CCCCN5C)CC4)cc3c2C)cc1OC CHEMBL4644864 IC50 850.0 nM
CCCCc1nc2c(N)nc3ccccc3c2s1 CHEMBL5272163 EC50 860.0 nM
CCCCc1nc2c(NN)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082336 EC50 873.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)O)cc3)nc12 CHEMBL5083582 EC50 890.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCNCCCO CHEMBL3964358 EC50 900.0 nM
O=C(NNC(=O)c1csc(-c2cccc(Br)c2)n1)c1ccccn1 CHEMBL4207325 IC50 900.0 nM
CCCCOc1nc(N)c2nc(O)n(CCCN3CCN(CC)CC3)c2n1 CHEMBL4437181 EC50 900.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(Cc1ccc(OCC(=O)OC)cc1)C(=O)CN1CCN(CCOC)CC1 CHEMBL5280038 EC50 904.0 nM
CCOCc1nc2c(N)nc3cc(Cl)ccc3c2n1CC(C)C CHEMBL4645797 EC50 910.0 nM
CCCC[C@@H](CO)Nc1nc(N)nc2cccnc12 CHEMBL4743925 EC50 910.0 nM
Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1cccnc1N1CCC[C@H]1CN1CCCC1 CHEMBL1837068 EC50 920.0 nM
COc1ccc(-c2[nH]c3ccc(C4CCN(Cc5cncn5C)CC4)cc3c2C)cc1OC CHEMBL4647316 IC50 920.0 nM
Cc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 CHEMBL1082304 EC50 955.0 nM
CCCCNc1nc(N)nc(C)c1CCCN(C)C CHEMBL4078632 EC50 958.0 nM
Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OCCOCCOCCC(F)(F)P(=O)(O)O)cc3C)cc12 CHEMBL3828542 EC50 980.0 nM
CN(C)CCCN(C)CCCOc1ccc(-c2nc3ccc(OCCCN(C)CCCN(C)C)cc3o2)cc1 CHEMBL4868248 IC50 980.0 nM
O=C(NNC(=O)c1csc(-c2ccc(C(F)(F)F)cc2)n1)c1ccccn1 CHEMBL4205530 IC50 990.0 nM
CCCCc1nc2c(N)nc3cc(C#N)ccc3c2n1CC(C)C CHEMBL4642371 EC50 990.0 nM
COC[C@H]1CCCN1CCCOc1ccc(-c2nc3ccc(OCCCN4CCC[C@@H]4COC)cc3o2)cc1 CHEMBL4853422 IC50 990.0 nM
CC(O)Cn1c(CC2CC2)nc2c(N)nc3ccccc3c21 CHEMBL5202177 EC50 990.0 nM