Cc1cc(-c2cc3[nH]nc(N[C@H]4CCNC[C@@H]4F)c3cc2C2CC2)cc(C)n1 CHEMBL5078689 IC50 0.05 nM
Cc1nc2c3c(c(-c4[nH]c5sc([C@@H]6C[C@@H]7C[C@H]6CN7CC(N)=O)c(C)c5c4C(C)C)cn2n1)CCC3 CHEMBL5277999 EC50 0.05 nM
Cc1cc(-c2cc3[nH]nc(N[C@@H]4CCNC[C@H]4F)c3cc2C2CC2)cc(C)n1 CHEMBL5091113 IC50 0.08 nM
Cc1nccc(-c2cc3[nH]nc(NC4CCN(C)CC4)c3cc2C2CC2)c1F CHEMBL5090067 IC50 0.08 nM
Cc1c(-c2cnc3c(c2)CNCC3)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5291249 EC50 0.08 nM
COc1ccc2c(-c3ccc(OCCCCO)c(C)c3)ccnc2c1 CHEMBL5399590 IC50 0.1 nM
Cc1c([C@@H]2C[C@@H]3C[C@H]2CN3CCS(C)(=O)=O)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5273537 EC50 0.11 nM
Cc1c(C2CC3(CNCCO3)C2)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5266091 EC50 0.18 nM
Cc1nccc(-c2cc3[nH]nc(N[C@H]4CCNC[C@@H]4F)c3cc2C2CC2)c1F CHEMBL5079910 IC50 0.2 nM
Cc1c(C2CC3(CCNC3)C2)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5272936 EC50 0.27 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(N6C[C@@H]7C[C@H]6CN7)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4878670 IC50 0.4 nM
O=c1ccc(-c2cc(C(F)(F)F)c3nn([C@H]4CCNC[C@@H]4F)cc3c2)c2n1CCC2 CHEMBL4641633 IC50 0.43 nM
COc1ccc2c(-c3ccc(O)c(C)c3)ccnc2c1 CHEMBL4790706 IC50 0.5 nM
Cc1c(C2CC3(CNCCO3)C2)sc2[nH]c(-c3cn4ncnc4c4c3CCC4)c(C(C)C)c12 CHEMBL5267703 EC50 0.54 nM
[2H]c1ccc2c(N3C[C@@H](C)N4Cc5nc(N6CCC7(CNC7)C6)ccc5[C@H]4C3)ccc(C#N)c2n1 CHEMBL4850085 IC50 0.7 nM
Cc1cc(-c2ccnc3cc(O)ccc23)ccc1O CHEMBL5176610 IC50 0.7 nM
Cc1cc(-c2cccc3cc(O)ccc23)ccc1O CHEMBL5274101 IC50 0.7 nM
COc1cc(-c2cc3[nH]c4ccc(C5CCNCC5)cc4c3c(C)c2C)cn2ncnc12 CHEMBL4849186 IC50 0.8 nM
COc1ccc2c(-c3cnc(OCc4ccccc4)c(C)c3)ccnc2c1 CHEMBL5397107 IC50 0.8 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccnc3)cc2N=C(N)C1 CHEMBL3971249 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncnc3)cc2N=C(N)C1 CHEMBL3946051 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3965526 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cc(C)cc(C)c3)cc2N=C(N)C1 CHEMBL3958421 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(C)cc3)cc2N=C(N)C1 CHEMBL3899088 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(CC)c3)cc2N=C(N)C1 CHEMBL3964498 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(OCC)nc3)cc2N=C(N)C1 CHEMBL3936078 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(OC)c3)cc2N=C(N)C1 CHEMBL3963860 EC50 1.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(OCC)c3)cc2N=C(N)C1 CHEMBL3963922 EC50 1.0 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2CN(c3cncc4c3CCNC4)CCN21 CHEMBL4799678 IC50 1.0 nM
Cc1cc(-c2nn(C)c3nc(N)ncc23)cnc1OCC12CCC(N)(CC1)CC2 CHEMBL4790219 IC50 1.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c(C)cn1 CHEMBL5178588 IC50 1.0 nM
Cc1cc(-c2ccnc3cc(Cl)ccc23)ccc1O CHEMBL5413646 IC50 1.0 nM
O=c1ccc(-c2cc(C(F)(F)F)c3nn([C@@H]4CCNC[C@H]4F)cc3c2)c2n1CCC2 CHEMBL4642652 IC50 1.1 nM
COc1cc2c(C(=O)N3CCN(C)CC3)n[nH]c2cc1-c1ccnc(C)c1F CHEMBL5077828 IC50 1.2 nM
COc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1ccnc(C)c1F CHEMBL5085458 IC50 1.2 nM
COc1cc(-c2cc3[nH]c4ccc(C5CCNCC5)cc4c3cc2C)cn2ncnc12 CHEMBL4872385 IC50 1.4 nM
Cc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1ccnc(C)c1F CHEMBL5085289 IC50 1.5 nM
CC1(N)CCN(c2ccc3c(n2)CN2CCN(c4ccc(C#N)c5ncccc45)C[C@@H]32)CC1 CHEMBL4863896 IC50 1.9 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(Cl)cc3)cc2N=C(N)C1 CHEMBL3970076 EC50 2.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C(=O)N4CCCC4)c3)cc2N=C(N)C1 CHEMBL3973387 EC50 2.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(C)c3)cc2N=C(N)C1 CHEMBL3969344 EC50 2.0 nM
CCCN(CCCO)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3922406 EC50 2.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(OC)c3)cc2N=C(N)C1 CHEMBL3949289 EC50 2.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(Cl)c3)cc2N=C(N)C1 CHEMBL3930313 EC50 2.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CN)c3)cc2N=C(N)C1 CHEMBL3968836 EC50 2.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccnnc3)cc2N=C(N)C1 CHEMBL3942748 EC50 2.0 nM
CCCN(CCC(F)(F)F)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3973620 EC50 2.0 nM
CCCN(CC1CC1)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3933372 EC50 2.0 nM
CCCN(CC(C)C)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3896793 EC50 2.0 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@H]2CN(c3cncc4c3CCNC4)CCN21 CHEMBL4745246 IC50 2.0 nM
Cc1cc(-c2cnc(OCC34CCC(N)(CC3)CC4)c(C)c2)c2cnn(C)c2n1 CHEMBL4762866 IC50 2.0 nM
COc1cc2cc[nH]c2cc1-c1ccncc1 CHEMBL5080083 IC50 2.0 nM
COc1cc2c(C(=O)N3CCN(C)CC3)n[nH]c2cc1-c1cc(C)nc(C)c1 CHEMBL5077018 IC50 2.5 nM
O=c1ccc(-c2cc(C(F)(F)F)c3nn(C4CCNCC4)cc3c2)c2n1CCC2 CHEMBL4644098 IC50 2.7 nM
Cc1cc(-c2[nH]c3cc(F)c(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5182126 IC50 2.7 nM
CCc1c(-c2ccnc(C)c2)[nH]c2cc(F)c(C3CCNCC3)c(F)c12 CHEMBL5174201 IC50 2.8 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CN)nc3)cc2N=C(N)C1 CHEMBL3908864 EC50 3.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncs3)cc2N=C(N)C1 CHEMBL3946092 EC50 3.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(F)c3)cc2N=C(N)C1 CHEMBL3925270 EC50 3.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(C)nc3)cc2N=C(N)C1 CHEMBL3981903 EC50 3.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(CCN)c3)cc2N=C(N)C1 CHEMBL3939801 EC50 3.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(CCCN)c3)cc2N=C(N)C1 CHEMBL3957505 EC50 3.0 nM
Cn1nc(-c2ccc(OCC34CCC(N)(CC3)CC4)c(F)c2)c2cnc(N)nc21 CHEMBL4748638 IC50 3.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)c(F)c3c2C(C)C)cc(C)n1 CHEMBL5176097 IC50 3.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 CHEMBL5201891 IC50 3.2 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(F)n1 CHEMBL5169693 IC50 3.8 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5190495 IC50 3.9 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncn3C)cc2N=C(N)C1 CHEMBL3913371 EC50 4.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CNC(=O)OCc4ccccc4)c3)cc2N=C(N)C1 CHEMBL3967094 EC50 4.0 nM
[2H]c1ccc2c(N3C[C@@H]4CN(c5ncc(N6CC7(CC(N)C7)C6)cc5C)CCN4[C@H](C)C3)ccc(C#N)c2n1 CHEMBL4755291 IC50 4.0 nM
C[C@@H]1CN(c2ccc(C#N)c3ncccc23)C[C@@H]2CN(CCc3ccc(N4C[C@@H](N)[C@@H](F)C4)nc3)CCN21 CHEMBL4747784 IC50 4.0 nM
Cc1cc(-c2ccc(=O)n3c2CCC3)cc2cn(C3CCNCC3)nc12 CHEMBL4649727 IC50 4.5 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(F)c3)cc2N=C(N)C1 CHEMBL3951961 EC50 5.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccccc3C)cc2N=C(N)C1 CHEMBL3973459 EC50 5.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C(F)(F)F)c3)cc2N=C(N)C1 CHEMBL3895602 EC50 5.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CCCN)cc3)cc2N=C(N)C1 CHEMBL3923648 EC50 5.0 nM
Cn1nc(-c2ccc(OC[C@H]3CC[C@H](N)CC3)c(F)c2)c2cnc(N)nc21 CHEMBL4783510 IC50 5.0 nM
C[C@H]1CN(c2ccc(C#N)c3nccnc23)C[C@@H]1C(=O)NC1CCN(C)CC1 CHEMBL5193543 IC50 5.0 nM
C[C@@H]1CN(c2ccc(C#N)n3ncc(F)c23)C[C@H](C(=O)NC2CCN(C)CC2)O1 CHEMBL5197568 IC50 5.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)N3CC4(C3)CN(c3ccc(C)cc3)C4)cc2N=C(N)C1 CHEMBL5418815 EC50 5.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccc(OC)c(OC)c4)c(C(C)C)c3c2)CC1 CHEMBL4636498 IC50 5.1 nM
C#CCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3935496 EC50 6.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(COCCOCCN)c3)cc2N=C(N)C1 CHEMBL3986818 EC50 6.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(/C=C\CN)c3)cc2N=C(N)C1 CHEMBL3940695 EC50 6.0 nM
CCCCN(CCO)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3945379 EC50 6.0 nM
[2H]c1ccc2c(N3CC4CN(c5ncc(N6CCOC[C@H](N)C6)cc5C)CCN4[C@@H](C)C3)ccc(C#N)c2n1 CHEMBL4795549 IC50 6.0 nM
CC(C)c1c(-c2ccncc2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5188600 IC50 6.1 nM
COc1cc(-c2cc(C)c3c(c2)[nH]c2ccc(C4CCNCC4)cc23)cn2ncnc12 CHEMBL4846672 IC50 6.8 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccccc3)cc2N=C(N)C1 CHEMBL3943393 EC50 7.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(F)cc3)cc2N=C(N)C1 CHEMBL3920750 EC50 7.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(CCCCN)c3)cc2N=C(N)C1 CHEMBL3984890 EC50 7.0 nM
CCN(C)CC(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5175791 IC50 7.0 nM
CC(C)c1c(-c2ccncc2CO)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5204983 IC50 7.6 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CO)c3)cc2N=C(N)C1 CHEMBL3956859 EC50 8.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(/C=C/CN)c3)cc2N=C(N)C1 CHEMBL3895819 EC50 8.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCc4ccccc4)c3)cc2N=C(N)C1 CHEMBL3972397 EC50 8.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CCCCN)nc3)cc2N=C(N)C1 CHEMBL3954257 EC50 8.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CCN(C)C)cc3)nc12 CHEMBL5094792 EC50 8.0 nM
COc1cc(-c2cc3[nH]nc(NC4CCN(C)CC4)c3cc2OC)ccn1 CHEMBL5089636 IC50 8.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(-c3cccc(C(=O)CC)c3)cc2N=C(N)C1 CHEMBL5435648 EC50 8.0 nM
Cc1cc(-c2cn(C)c(=O)c3ccoc23)cc2cn(C3CCNCC3)nc12 CHEMBL4634366 IC50 8.9 nM
CCCCCc1cc2c(CCCCCN)cccc2nc1N CHEMBL3622854 EC50 9.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CN)cc3)cc2N=C(N)C1 CHEMBL3961755 EC50 9.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC7(CNCCO7)C6)ccc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5075053 IC50 9.0 nM
COc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 CHEMBL5201981 IC50 9.4 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(S(C)(=O)=O)c3)cc2N=C(N)C1 CHEMBL3975213 EC50 10.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(OCCCCCN)c3)cc2N=C(N)C1 CHEMBL3984631 EC50 10.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCCN)c3)cc2N=C(N)C1 CHEMBL3963744 EC50 10.0 nM
CCCN(CCCOCCCN)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3971469 EC50 10.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCc4cccc(OC)c4)c3)cc2N=C(N)C1 CHEMBL3922874 EC50 10.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CCCN)nc3)cc2N=C(N)C1 CHEMBL3929430 EC50 10.0 nM
Cn1nc(-c2ccc(OCC3CC4(CNC4)C3)c(F)c2)c2cnc(N)nc21 CHEMBL4761527 IC50 10.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3)nc12 CHEMBL5077799 EC50 10.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6C[C@H]7NCCO[C@@H]7C6)cnc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5076307 IC50 10.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(F)c(CCN)c3)cc2N=C(N)C1 CHEMBL3891617 EC50 11.0 nM
Cc1c(-c2cc(C3CC3)c3nn(C4CCNCC4)cc3c2)ccc(=O)n1C CHEMBL4647201 IC50 11.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)NC(c3ccccc3)c3ccccc3)cc2N=C(N)C1 CHEMBL5415035 EC50 11.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCc4ccc(OC)cc4)c3)cc2N=C(N)C1 CHEMBL3932895 EC50 12.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CN(C)C)c3)cc2N=C(N)C1 CHEMBL3930119 EC50 12.0 nM
Cc1cc(-c2cc(C)c3c(c2)[nH]c2ccc(C4CCN(CC(C)(C)O)CC4)cc23)cc(C)n1 CHEMBL4854009 IC50 12.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CC5(COC5)C4)cc3)nc12 CHEMBL5079043 EC50 12.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccncc3)cc2N=C(N)C1 CHEMBL3915422 EC50 13.0 nM
Cc1cc(-c2ccc(=O)n(C)c2F)cc2cn(C3CCNCC3)nc12 CHEMBL4633872 IC50 13.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(CN)c1 CHEMBL1271705 EC50 14.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(C(=O)N4CCCC4)c3)cc2N=C(N)C1 CHEMBL3940440 EC50 14.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CO)nc3)cc2N=C(N)C1 CHEMBL3907895 EC50 15.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cc(C)cc(CN)c3)cc2N=C(N)C1 CHEMBL3895772 EC50 15.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CCCCCN)cc3)cc2N=C(N)C1 CHEMBL3892090 EC50 15.0 nM
Cn1c(F)c(-c2cc(C(F)(F)F)c3nn(C4CCNCC4)cc3c2)ccc1=O CHEMBL4647559 IC50 15.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCCC4)cc3)nc12 CHEMBL5083795 EC50 15.0 nM
CCc1c(-c2ccnc(C)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5179092 IC50 15.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)CN5CCCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5403827 IC50 15.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(C#CCN)c3)cc2N=C(N)C1 CHEMBL3935182 EC50 16.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC(C)(N)C6)ncc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5091915 IC50 16.0 nM
CCCCN(CCCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3922493 EC50 17.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCN)c3)cc2N=C(N)C1 CHEMBL3917664 EC50 17.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC(N)C6)ccc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5081117 IC50 17.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CCN)cc3)cc2N=C(N)C1 CHEMBL3931979 EC50 18.0 nM
Cc1c(-c2cc(C(F)(F)F)c3nn(C4CCNCC4)cc3c2)ccc(=O)n1C CHEMBL4632520 IC50 18.0 nM
Cn1ncc2c(-c3ccc(OCC45CCC(N)(CC4)CC5)c(F)c3)nc(N)nc21 CHEMBL4740820 IC50 18.0 nM
[2H]c1ccc2c(N3C[C@H](CN4CC5(C4)OCc4cc(N6CC(C)(N)C6)ccc45)O[C@H](C)C3)ccc(C#N)c2n1 CHEMBL5094595 IC50 19.0 nM
Cn1nc(-c2ccc(OC[C@H]3CC[C@@H](N)CC3)c(F)c2)c2cnc(N)nc21 CHEMBL4782200 IC50 20.0 nM
COc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1ccncc1 CHEMBL5086681 IC50 20.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5C[C@@H](C)O[C@@H](C)C5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5419406 IC50 20.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccnc3C)cc2N=C(N)C1 CHEMBL3953150 EC50 21.0 nM
Cc1cc(-c2cc(C)c3c(c2)[nH]c2ccc(C4CCNCC4)cc23)cc(C)n1 CHEMBL4865326 IC50 21.0 nM
Cc1nccc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c1C CHEMBL5184042 IC50 22.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c(C)c(C)n1 CHEMBL5183412 IC50 22.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccn(C)n3)cc2N=C(N)C1 CHEMBL3913146 EC50 23.0 nM
COCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3)nc12 CHEMBL5085705 EC50 23.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCCCN)c3)cc2N=C(N)C1 CHEMBL3957004 EC50 24.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(CCCCCN)c3)cc2N=C(N)C1 CHEMBL3914070 EC50 25.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCCCCN)c3)cc2N=C(N)C1 CHEMBL3938389 EC50 25.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)CN(C)C)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5432728 IC50 25.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(OCCOCCN)c3)cc2N=C(N)C1 CHEMBL3906274 EC50 26.0 nM
Cn1nc(-c2ccc(OCCCC3CCNCC3)c(F)c2)c2cnc(N)nc21 CHEMBL4755173 IC50 26.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3OC)nc12 CHEMBL5090317 EC50 26.0 nM
CCCCCc1cc2c(CCCCN)cccc2nc1N CHEMBL3622853 EC50 27.0 nM
CCCN(Cc1ccc(CN)cc1)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3966671 EC50 27.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCCCCCN)c3)cc2N=C(N)C1 CHEMBL3947170 EC50 27.0 nM
CCc1c(-c2ccnc(C)c2)[nH]c2ccc(C3CCNCC3)c(C)c12 CHEMBL5180395 IC50 27.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3nccs3)cc2N=C(N)C1 CHEMBL3962164 EC50 29.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ncco3)cc2N=C(N)C1 CHEMBL3916641 EC50 29.0 nM
CCCN(CCCO)C(=O)C1=Cc2ccc(C(=O)Nc3cccnc3)cc2N=C(N)C1 CHEMBL3900503 EC50 29.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cc(Cl)cc(CCN)c3)cc2N=C(N)C1 CHEMBL3980029 EC50 29.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCc4ccc(CN)cc4)c3)cc2N=C(N)C1 CHEMBL3910450 EC50 29.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1Cc2ccccc2C1 CHEMBL4096879 EC50 29.0 nM
CSc1nnc(CCCO)n1-c1cc(C)c(C)c(C)c1 CHEMBL4519240 IC50 30.0 nM
Cc1cc(-c2ccc(=O)n(C)c2Cl)cc2cn(C3CCNCC3)nc12 CHEMBL4635717 IC50 30.0 nM
Cc1c(-c2cc(Cl)c3nn(C4CCNCC4)cc3c2)ccc(=O)n1C CHEMBL4635547 IC50 30.0 nM
CCOC(=O)C1=Cc2ccc(-c3cccc(C#N)c3)cc2N=C(N)C1 CHEMBL5275885 EC50 30.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCOCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5409292 IC50 30.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(CN)c3)cc2N=C(N)C1 CHEMBL3908120 EC50 31.0 nM
CCCN(CCCOCCOCCN)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 CHEMBL3930709 EC50 31.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(OCCN)c3)cc2N=C(N)C1 CHEMBL3918347 EC50 31.0 nM
COc1cc2c(C(=O)N3CCN(C)CC3)n[nH]c2cc1-c1ccncc1 CHEMBL5081397 IC50 31.0 nM
Cc1cnccc1-c1[nH]c2ccc(C3CCNCC3)cc2c1C(C)C CHEMBL5179724 IC50 32.0 nM
Cc1cc(-c2cc(C)c3nn(C4CCNCC4)cc3c2)cn(C)c1=O CHEMBL4643502 IC50 33.0 nM
O=c1ccc(-c2cc(C(F)(F)F)c3nn([C@@H]4CCNC[C@@H]4F)cc3c2)c2n1CCC2 CHEMBL4632846 IC50 33.0 nM
COc1cc2c(NC3CCN(C)CC3)n[nH]c2cc1-c1cc(C)nc(C)c1 CHEMBL5083541 IC50 33.0 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(C3CCN(C(=O)CN(C)C)CC3)nc12 CHEMBL4640935 IC50 35.0 nM
CCCCCc1cc2c(Cc3ccc(CN)cc3)cccc2nc1N CHEMBL3622846 EC50 38.0 nM
COCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCCC4)cc3)nc12 CHEMBL5087987 EC50 38.0 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(C3CCNCC3)nc12 CHEMBL4641604 IC50 39.0 nM
Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C2CC2)n1 CHEMBL5197134 IC50 39.0 nM
Cc1cc(-c2ccc(OCC34CCC(N)(CC3)CC4)c(F)c2)c2cnc(N)nn12 CHEMBL4792072 IC50 40.0 nM
C[C@@H]1CN(c2ccc(C#N)n3nccc23)C[C@H](CN2CC3(C2)OCc2cc(N4CC5(CN(C)C5)C4)ccc23)O1 CHEMBL5092293 IC50 40.0 nM
CCNCC(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5405740 IC50 44.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCN(C)CC5=O)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5423714 IC50 44.0 nM
Cc1cc(-c2ccc(=O)n(C)c2)cc2cnc(N3CCN(C(C)C)CC3)nc12 CHEMBL4637821 IC50 45.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCOCC4)cc3)nc12 CHEMBL5083597 EC50 45.0 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(C3CCN(C)CC3)nc12 CHEMBL4633423 IC50 47.0 nM
CCCCCc1cc2c(Cc3cccc(CN)c3)cccc2nc1N CHEMBL3622844 EC50 49.0 nM
CCCC[C@](C)(CO)Nc1nc(N)nc2cc(F)cnc12 CHEMBL4594258 MEC 49.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)N(C)C)cc3)nc12 CHEMBL5071236 EC50 49.0 nM
Nc1nc2ccccc2c2c1nc(CCCc1nc3c(N)nc4ccccc4c3n1Cc1ccccc1)n2Cc1ccccc1 CHEMBL2018888 IC50 50.0 nM
CCCCCc1cc2ccc(CCCCCN)cc2nc1N CHEMBL3622862 EC50 50.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(OCCN(C)C)cc3)nc12 CHEMBL5079616 EC50 50.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)c(OC)c3)nc12 CHEMBL5079288 EC50 50.0 nM
COCCNC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5432727 IC50 50.0 nM
COc1cc2cn[nH]c2cc1-c1ccncc1 CHEMBL5089903 IC50 51.0 nM
CCOCc1nc2c(N)nc3cc(CCC(=O)OCC)ccc3c2n1CC(C)(C)OC(=O)CN CHEMBL3967031 EC50 54.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccc(CN)cc1 CHEMBL1271706 EC50 55.0 nM
CCCCCc1cc2c(CCCCCCN)cccc2nc1N CHEMBL3622855 EC50 56.0 nM
CCCCn1cc2c(n1)c(N)nc1ccccc12 CHEMBL5400758 EC50 56.0 nM
CCCCNc1nc(N)nc2ccc(Cc3cccc(CN(C)C)c3)nc12 CHEMBL5076212 EC50 59.0 nM
CCCCCc1cc2ccc(CCCCN)cc2nc1N CHEMBL3622861 EC50 60.0 nM
Cn1nc(-c2ccc(OCC3CCNCC3)c(F)c2)c2cnc(N)nc21 CHEMBL4776103 IC50 60.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)CN5CCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5435782 IC50 60.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CN2CCCC2)cc1OC CHEMBL5280242 pEC50 63.1 nM
CC[N+]1=C(/C=C/C=C/C=C2/N(CCCCCC(=O)NC34CCC(COc5ncc(-c6ccnc7[nH]ncc67)cc5C)(CC3)CC4)c3ccc(S(=O)(=O)O)cc3C2(C)C)C(C)(C)c2cc(S(=O)(=O)O)ccc21 CHEMBL4646526 Kd 65.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)N4CCCC4)cc3)nc12 CHEMBL5088082 EC50 67.0 nM
Cc1cccc(-c2ccnc3c(C(N)=O)cnn23)c1 CHEMBL4553089 IC50 67.0 nM
Cc1cccc(-c2cccc3c(C(N)=O)cnn23)c1 CHEMBL5277457 IC50 67.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)[C@@H]5CNCCO5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5430709 IC50 67.0 nM
Cc1cc(-c2ccnc3[nH]ncc23)cnc1OCC12CCC(N)(CC1)CC2 CHEMBL4634860 IC50 68.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)[C@@H]5COCCN5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5417170 IC50 68.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC5CCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5430815 IC50 71.0 nM
CCc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1 CHEMBL5186413 IC50 72.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1cccc(CN)c1 CHEMBL5414658 EC50 72.0 nM
Cn1nc(-c2ccc(OCC34CCC(O)(CC3)CC4)c(F)c2)c2cnc(N)nc21 CHEMBL4745239 IC50 75.0 nM
COCCNc1nc(N)nc2ccc(Cc3ccc(CN4CCOCC4)cc3)nc12 CHEMBL5073114 EC50 75.0 nM
CC(C)c1c(-c2ccnc(CO)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5196314 IC50 75.0 nM
Cc1cc(=O)n(C)cc1-c1cc(C)c2nn(C3CCNCC3)cc2c1 CHEMBL4642538 IC50 76.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OC(=O)CN CHEMBL3921751 EC50 80.0 nM
CCCCCc1cc2ccc(CCCCCCN)cc2nc1N CHEMBL3622863 EC50 85.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5421376 IC50 85.0 nM
O=[N+]([O-])c1c(I)cccc1Oc1ccc(-c2nnco2)cc1 CHEMBL4543348 Kd 85.5 nM
Cn1nc(-c2ccc(OCC3C[C@H]4CC[C@@H](C3)N4)c(F)c2)c2cnc(N)nc21 CHEMBL4796453 IC50 88.0 nM
CCCCCc1cc2c(CCCN)cccc2nc1N CHEMBL3622852 EC50 91.0 nM
Cn1cc(-c2ccc3nc(N4CCN(C5CCC5)CC4)ncc3c2)ccc1=O CHEMBL4646719 IC50 91.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCN(c2ccccc2)CC1 CHEMBL4092273 EC50 92.0 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(C3CCCNC3)nc12 CHEMBL4648996 IC50 93.0 nM
COc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5194452 IC50 93.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(COC)cc3)nc12 CHEMBL5090751 EC50 95.0 nM
CC(C)c1c(-c2ccnc(C3CC3)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5175964 IC50 99.0 nM
CCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O CHEMBL1082983 EC50 100.0 nM
CCCN(CCC)C(=O)C1=Cc2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2N=C(N)C1 CHEMBL3301618 EC50 100.0 nM
CCCN(CCC)C(=O)/C1=C/c2ccc(-c3ccc(C(=O)N4CCCC4)cc3)cc2/N=C(/N)CC1 CHEMBL5290445 EC50 100.0 nM
CCCCNc1nc(N)nnc1OCCCN(C)C CHEMBL5272274 EC50 100.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CN2CCN(C)CC2)cc1OC CHEMBL5283533 pEC50 100.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccccc3CN(C)C)nc12 CHEMBL5091330 EC50 102.0 nM
Cc1cc(-c2ccc3c(c2)[nH]c2ccc(C4CCNCC4)cc23)cc(C)n1 CHEMBL4856345 IC50 103.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCCC1 CHEMBL4105319 EC50 110.0 nM
CSc1nnc(CCCO)n1-c1cc(Cl)c(Cl)c(Cl)c1 CHEMBL4530243 IC50 110.0 nM
CCCCCc1c(N)nc2ccccc2c1Cc1ccc(CN)cc1 CHEMBL3622840 EC50 120.0 nM
CC(C)c1c(-c2ccnc(C(F)(F)F)c2)[nH]c2ccc(C3CCNCC3)cc12 CHEMBL5179188 IC50 120.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5407646 IC50 120.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CO)cc3)nc12 CHEMBL5091071 EC50 124.0 nM
CCCCNc1nc(N)nc2ccc(CCc3ccc(CN(C)C)cc3)nc12 CHEMBL5080899 EC50 125.0 nM
CCCCNc1nc(N)nc(C)c1CCCN(C)C CHEMBL4078632 EC50 126.0 nM
CCCCNc1nc(N)nc(C)c1CCCCN1CCOCC1 CHEMBL4063952 EC50 128.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN(C)C)cc3)cc12 CHEMBL5080244 EC50 128.0 nM
Cc1cc(-c2[nH]c3cc(C)c(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5201441 IC50 130.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCCCC1 CHEMBL4061978 EC50 133.0 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(-c3cccnc3)nc12 CHEMBL4647012 IC50 140.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NCC(F)F)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5400499 IC50 140.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)N4CCOCC4)cc3)nc12 CHEMBL5073954 EC50 145.0 nM
CCCCCc1c(N)nc2ccccc2c1Cc1cccc(CN)c1 CHEMBL3622839 EC50 150.0 nM
CCCC[C@](C)(CO)Nc1nc(N)nc2cc(C)cnc12 CHEMBL4741976 EC50 160.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N(C)C)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5406817 IC50 160.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCSCC1 CHEMBL4083025 EC50 167.0 nM
CCCC[C@](C)(CO)Nc1nc(N)nc2cccnc12 CHEMBL4793023 EC50 170.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCCCCC1 CHEMBL4088953 EC50 178.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCN(C)CC1 CHEMBL4071479 EC50 179.0 nM
CCCCc1nc2c(N)nc3ccccc3c2o1 CHEMBL5430530 EC50 180.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC5COC5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5398965 IC50 180.0 nM
CCCCCc1c(N)nc2ccccc2c1CCCCN CHEMBL3622841 EC50 190.0 nM
CSc1nnc(CCCO)n1-c1ccc(Cl)c(Cl)c1 CHEMBL4452260 IC50 190.0 nM
CN[C@H](C)C(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5429312 IC50 190.0 nM
CN[C@@H](C)C(=O)NC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5405310 IC50 190.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NCC(=O)N(C)C)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5435544 IC50 190.0 nM
CCCCCc1cc2ccccc2nc1N CHEMBL3622866 EC50 200.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccncc4)c(C)c3c2)CC1 CHEMBL5189004 IC50 200.0 nM
CCCCc1nc2c(N)nc3ccccc3c2s1 CHEMBL5272163 EC50 200.0 nM
CCCCNc1nc(N)nc(C)c1CCCN(C)CCOC CHEMBL4069818 EC50 203.0 nM
CSc1nnc(CCCO)n1-c1cccc(C(F)(F)F)c1 CHEMBL4461378 IC50 210.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5431871 IC50 210.0 nM
Cc1nc(C)c(C)c(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)c1C CHEMBL5205027 IC50 220.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(NC(=O)[C@H]5COCCN5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5411489 IC50 220.0 nM
CCCCCc1c(N)nc2ccccc2c1CCCCCN CHEMBL3622842 EC50 250.0 nM
CCCCNc1nc(N)nc(C)c1CCCN(CC)CC CHEMBL4096648 EC50 254.0 nM
CCOCc1nc2c(N)nc3cc(CCC(=O)OCC)ccc3c2n1CC(C)(C)OCCN CHEMBL3984333 EC50 256.0 nM
CCCC[C@](C)(CO)Nc1nc(N)nc2cc(Cl)cnc12 CHEMBL4779745 EC50 270.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCOCC1 CHEMBL4090816 EC50 280.0 nM
CSc1nnc(CCCO)n1-c1ccc(Cl)cc1Cl CHEMBL4451165 IC50 290.0 nM
CSc1nnc(CCCO)n1-c1cccc(C)c1 CHEMBL4539893 IC50 290.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCN(C(=O)OC(C)(C)C)CC1 CHEMBL4086479 EC50 300.0 nM
CCCCNc1nc(N)nc(C)c1CCCCCN CHEMBL4437744 EC50 300.0 nM
CCCCNc1nc(N)nc(C)c1CCCCN CHEMBL4522643 EC50 300.0 nM
Cc1cc(-c2ccc(=O)n(C)c2C)cc2cn(C3CNCCC3(F)F)nc12 CHEMBL4635744 IC50 300.0 nM
Cc1cc(-c2ccc(=O)n(C)c2)cc2cn(C3CCNCC3)nc12 CHEMBL4639145 IC50 320.0 nM
CCCCNc1nc(N)nnc1OCc1ccccn1 CHEMBL5273911 EC50 330.0 nM
CNC12CCC(Cn3nc(C)c4c3CCN(c3cc(C)nc5c3cnn5C)C4)(CC1)CC2 CHEMBL5434008 IC50 330.0 nM
CSc1nnc(CCCO)n1-c1cccc(Cl)c1 CHEMBL4471285 IC50 350.0 nM
CCCCNc1nc(N)nc(C)c1CCCn1c(C)nc2ccccc21 CHEMBL4093530 EC50 366.0 nM
CCCCCNc1oc2c(C)ncc(CO)c2c1Nc1cccc(F)c1 CHEMBL2177865 EC50 370.0 nM
CCSc1nnc(CCCO)n1-c1ccc(Cl)cc1Cl CHEMBL4535822 IC50 390.0 nM
CSc1nnc(CCCO)n1-c1cccc2ccccc12 CHEMBL4590994 IC50 390.0 nM
Cc1cc(N2CCc3c(c(C)nn3CC34CCC(N5CCN(C)C(=O)C5)(CC3)CC4)C2)c2cnn(C)c2n1 CHEMBL5402315 IC50 400.0 nM
CCCCc1cc2ccccc2nc1N CHEMBL5291029 EC50 410.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN)cc1 CHEMBL5409349 EC50 410.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCc2cc[nH]c2)cc1 CHEMBL5435125 EC50 410.0 nM
CCCC[C@@H](CO)Nc1nc(N)nc2cccnc12 CHEMBL4743925 EC50 420.0 nM
Cc1cc(-c2[nH]c3cc(C(F)(F)F)c(C4CCNCC4)cc3c2C(C)C)ccn1 CHEMBL5176324 IC50 420.0 nM
CCCCc1nc2c(NC(=O)CCC)nc3ccccc3c2s1 CHEMBL5282164 EC50 420.0 nM
CCC[C@@H](CO)Nc1nc(N)nc2cccnc12 CHEMBL4740836 EC50 430.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1C(=O)c2ccccc2C1=O CHEMBL4069667 EC50 453.0 nM
CCCCNc1nc(N)nnc1OC(C)C CHEMBL5269895 EC50 460.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNC)cc1 CHEMBL5395556 EC50 460.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O CHEMBL383322 EC50 480.0 nM
CCC[C@@H](CO)Nc1nc(N)nc(C)c1Cc1ccc(CN(C)C)cc1OC CHEMBL5277107 pEC50 489.78 nM
CNCCN1CCC(c2ccc3[nH]c(-c4ccc(OC)c(OC)c4)c(C)c3c2)CC1 CHEMBL4647818 IC50 490.0 nM
C=CCCCc1cc2ccccc2nc1N CHEMBL5280690 EC50 490.0 nM
CCCCNc1nc(N)nc(C)c1CCCN1CCNCC1 CHEMBL4104376 EC50 500.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CP(=O)(OCC)OCC)cc3)nc12 CHEMBL5090854 EC50 501.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN2CCCC2)cc1OC CHEMBL5276889 pEC50 501.19 nM
CCCCCc1cc2cc(CCCCCN)ccc2nc1N CHEMBL3622859 EC50 519.0 nM
CSc1nnc(CCCCCO)n1-c1ccc(Cl)cc1Cl CHEMBL4585768 IC50 520.0 nM
CCCCc1nc2c(N)nc3cc(C)sc3c2n1Cc1ccc(CN)cc1 CHEMBL5406954 EC50 540.0 nM
CSc1nnc(CO)n1-c1ccc(Cl)cc1Cl CHEMBL4564658 IC50 550.0 nM
CCC[C@H](CCO)Nc1nc(N)nnc1OCc1nccc(OC)c1OC CHEMBL5280595 EC50 560.0 nM
CCCCNc1nc(N)nnc1OCc1ccccc1F CHEMBL5267126 EC50 560.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN(C)C)cc1 CHEMBL5406627 EC50 578.0 nM
CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN CHEMBL3904306 EC50 580.0 nM
CCCCC[C@](C)(CO)Nc1nc(N)nc2cccnc12 CHEMBL4753395 EC50 580.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CNC)cc3)nc12 CHEMBL5082702 EC50 580.0 nM
CSc1nnc(CCO)n1-c1ccc(Cl)cc1Cl CHEMBL4445770 IC50 590.0 nM
CCCCNc1nc(N)nnc1OCc1cccnc1 CHEMBL5281452 EC50 590.0 nM
CSc1nnc(CCCO)n1-c1ccc(Cl)c(Cl)c1Cl CHEMBL4468868 IC50 600.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CN(CC)CC)cc1 CHEMBL5413112 EC50 617.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C(=O)O)cc3)nc12 CHEMBL5083582 EC50 620.0 nM
CNCCN1CCC(c2ccc3[nH]c(-c4cncc(OC)c4)c(C)c3c2)CC1 CHEMBL5192984 IC50 620.0 nM
CCCCCc1cc2c(CCCCCN)cc(CCCCCN)cc2nc1N CHEMBL3622865 EC50 621.0 nM
CCCc1nnc(SC)n1-c1ccc(Cl)cc1Cl CHEMBL4449343 IC50 630.0 nM
CCC[C@@H](CCO)Nc1nc(N)nc(C)c1Cc1ccc(CN2CCN(C)CC2)cc1OC CHEMBL5285492 pEC50 630.96 nM
CCCCNc1nc(N)nnc1OCc1ccccc1OC CHEMBL5285197 EC50 640.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(C#N)cc3)nc12 CHEMBL5092548 EC50 660.0 nM
CCCCCc1cc2c(-c3ccc(CN)cc3)cccc2nc1N CHEMBL3622851 EC50 699.0 nM
CCCC[C@@H](CO)Nc1nc(N)nc2ccccc12 CHEMBL4161854 EC50 710.0 nM
CCCCCc1cc2cc(CCCCN)ccc2nc1N CHEMBL3622858 EC50 727.0 nM
CCCCNc1nc(N)nc(C)c1CCCc1ccccc1 CHEMBL4103710 EC50 749.0 nM
CCCCNc1nc(N)nc2ccc(Cc3cccc(C#N)c3)nc12 CHEMBL5077793 EC50 750.0 nM
O=[N+]([O-])c1c(Cl)cccc1Oc1ccc(-c2nnco2)cc1 CHEMBL4467356 IC50 770.0 nM
CCCCNc1nc(N)nc(C)c1CCCC CHEMBL4103230 EC50 780.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1nc(CN)cs1 CHEMBL5395202 EC50 780.0 nM
CCCC[C@H](CO)Nc1nc(N)nc2cccnc12 CHEMBL4750957 EC50 790.0 nM
CSc1nnc(CCCO)n1-c1cccc(Cl)c1Cl CHEMBL4446241 IC50 800.0 nM
COCCNc1nc(N)nc2ccc(Cc3ccccc3)nc12 CHEMBL5094238 EC50 800.0 nM
CCCc1nc2c(N)nc3ccccc3c2s1 CHEMBL512901 EC50 800.0 nM
CCc1nc2c(N)nc3ccccc3c2s1 CHEMBL5283645 EC50 810.0 nM
CCCCNc1nc(N)nc(C)c1CCCCCc1ccccc1 CHEMBL4095966 EC50 830.0 nM
CCCCCNc1oc2c(C)ncc(CO)c2c1Nc1cccc([N+](=O)[O-])c1 CHEMBL2177866 EC50 850.0 nM
CCCCNc1nc(N)nc(C)c1CCCCc1ccccc1 CHEMBL4085784 EC50 857.0 nM
N#Cc1c(Br)cccc1Oc1ccc(-c2nnco2)cc1 CHEMBL4593624 IC50 880.0 nM
CCCc1nc2c(NC=O)nc3ccccc3c2s1 CHEMBL5278700 EC50 880.0 nM
CCc1c(-c2ccnc(C)c2)[nH]c2c(F)cc(C3CCNCC3)cc12 CHEMBL5191852 IC50 910.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCCCCO)cc1 CHEMBL5420662 EC50 930.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccccc3)nc12 CHEMBL5088598 EC50 950.0 nM
CCCCNc1nc(N)nc2ccc(Cc3ccc(CN)cc3)nc12 CHEMBL5082922 EC50 960.0 nM
CSc1nnc(CCCO)n1-c1ccccc1Cl CHEMBL4451720 IC50 980.0 nM
CCCCc1nc2c(N)nc3ccsc3c2n1Cc1ccc(CNCCO)cc1 CHEMBL5429987 EC50 990.0 nM
CCCCCc1cc2c(Cc3ccccc3CN)cccc2nc1N CHEMBL3622847 EC50 1000.0 nM
CCCCNc1nc(N)nnc1OCCOC CHEMBL5270391 EC50 1000.0 nM