Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)sc1CCC(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3639418 Ki 0.13 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642979 Ki 0.14 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)N[C@@H](CC(=O)O)C(=O)O)CCC3)s2)c(F)c1 CHEMBL3667879 Ki 0.14 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CSC[C@H]3C(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3921980 Ki 0.15 nM
N=C(N)c1ccc(OC(=O)c2cc3c(s2)CN(C(=O)N[C@@H](CC(=O)O)C(=O)O)CC3)c(F)c1 CHEMBL3915122 Ki 0.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642960 Ki 0.21 nM
C=CCN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667883 Ki 0.24 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(C(=O)O)c(C(=O)O)c1 CHEMBL3672880 Ki 0.24 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](Cc1nn[nH]n1)C(=O)O CHEMBL3977688 Ki 0.24 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3900248 Ki 0.24 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3914629 Ki 0.24 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642886 Ki 0.25 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3667897 Ki 0.26 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3667903 Ki 0.26 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642957 Ki 0.27 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3667902 Ki 0.27 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642902 Ki 0.28 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Br)s1)C(=O)O CHEMBL3642898 Ki 0.29 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCC(=O)O CHEMBL3667881 Ki 0.29 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1C[C@H](O)C[C@H]1C(=O)O CHEMBL4109414 Ki 0.3 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(CCC(=O)O)C(=O)O)o2)cc1 CHEMBL3642925 Ki 0.31 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642948 Ki 0.31 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)O)c1 CHEMBL3672872 Ki 0.31 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)co1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642931 Ki 0.32 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642910 Ki 0.33 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642947 Ki 0.33 nM
CC(C)N(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3951843 Ki 0.33 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642912 Ki 0.35 nM
CC(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642924 Ki 0.35 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCP(=O)(O)O CHEMBL3642958 Ki 0.37 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)NCP(=O)(O)O)s2)c(F)c1 CHEMBL3642962 Ki 0.38 nM
CC(C)N(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3967865 Ki 0.38 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3965069 Ki 0.38 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3920627 Ki 0.38 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642922 Ki 0.39 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)cs1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642968 Ki 0.39 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)ccc1C(=O)O CHEMBL3672887 Ki 0.39 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3897603 Ki 0.39 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642909 Ki 0.4 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642951 Ki 0.4 nM
CC(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3642965 Ki 0.41 nM
CN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667885 Ki 0.41 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3667889 Ki 0.41 nM
N=C(N)Nc1ccc2c(c1)CCCOc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5415486 IC50(app) 0.41 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642879 Ki 0.42 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1 CHEMBL3642926 Ki 0.42 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)O CHEMBL3642899 Ki 0.42 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3642901 Ki 0.42 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2Cl)s1)C(=O)NCP(=O)(O)O CHEMBL3642959 Ki 0.42 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CCC(=O)O)C(=O)O CHEMBL3672856 Ki 0.42 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(=O)O)c1nnn[nH]1 CHEMBL3891548 Ki 0.43 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3890156 Ki 0.43 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCCC[C@H]3C(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3924838 Ki 0.44 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642911 Ki 0.46 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3667882 Ki 0.46 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642961 Ki 0.48 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)c(F)c2)s1)C(=O)O CHEMBL3642906 Ki 0.49 nM
CCCN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667888 Ki 0.49 nM
CCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642882 Ki 0.5 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642907 Ki 0.5 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642904 Ki 0.5 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CCC(=O)O)CC(=O)O)s2)c(F)c1 CHEMBL3642953 Ki 0.5 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642952 Ki 0.51 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CCC1 CHEMBL3672869 Ki 0.51 nM
CC(Cc1coc(C(=O)Oc2ccc(C(=N)N)cc2)c1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642932 Ki 0.52 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)c(F)c2)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642946 Ki 0.52 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)co1)C(=O)O CHEMBL3642928 Ki 0.53 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(O)c(C(=O)O)c1 CHEMBL3672860 Ki 0.53 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCc1nnn[nH]1 CHEMBL3672876 Ki 0.53 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1nnn[nH]1 CHEMBL3672877 Ki 0.53 nM
CC(C)C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3969696 Ki 0.53 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N(CCC(=O)O)CC(=O)O)s2)c(F)c1 CHEMBL4108738 Ki 0.53 nM
C=CCN(C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)[C@@H](CC(=O)O)C(=O)O CHEMBL3642978 Ki 0.55 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(C(=O)O)c(C(=O)O)c1 CHEMBL3975448 Ki 0.55 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3642903 Ki 0.56 nM
CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3960291 Ki 0.56 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CCC(=O)O)C(=O)O CHEMBL3642878 Ki 0.57 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1 CHEMBL3642889 Ki 0.57 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CCC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642977 Ki 0.57 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)S(=O)(=O)O CHEMBL3642887 Ki 0.58 nM
CCC[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642945 Ki 0.58 nM
N=C(N)c1ccc(OC(=O)c2csc(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)c2)c(F)c1 CHEMBL3642970 Ki 0.58 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(O)cc(C(=O)O)c1 CHEMBL3672886 Ki 0.58 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N(CCC(=O)O)CC(=O)O)o2)cc1 CHEMBL3642919 Ki 0.6 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642870 Ki 0.61 nM
CC(C)C[C@@H](C(=O)N[C@H](CCC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL4108694 Ki 0.61 nM
N=C(N)c1ccc(OC(=O)c2ccc(Cn3cccc3C(=O)O)s2)c(F)c1 CHEMBL3897108 Ki 0.61 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642861 Ki 0.62 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(=O)O)o2)cc1 CHEMBL3642883 Ki 0.62 nM
C=CCN(C(=O)CN1CCc2cc(C(=O)Oc3ccc(C(=N)N)cc3F)sc2C1)[C@@H](CCC(=O)O)C(=O)O CHEMBL3957106 Ki 0.62 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(C(=O)O)C1 CHEMBL3672884 Ki 0.63 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)O)o2)cc1 CHEMBL3642888 Ki 0.64 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL3642976 Ki 0.64 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)o1)C(=O)O CHEMBL3642884 Ki 0.65 nM
CC[C@H](NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667906 Ki 0.65 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)o2)cc1 CHEMBL3916604 Ki 0.65 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1 CHEMBL3642890 Ki 0.67 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(N)=O)C(=O)O CHEMBL3672857 Ki 0.67 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CC1 CHEMBL3672870 Ki 0.67 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N(CC(=O)O)CC1CC1 CHEMBL3672888 Ki 0.67 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)c1ccc(O)cc1 CHEMBL3903777 Ki 0.67 nM
N=C(N)c1ccc2cc(OC(=O)c3ccc(CN4CCC[C@@H]4C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)o3)ccc2c1 CHEMBL3944540 Ki 0.67 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CC(=O)O)CC(=O)O CHEMBL3639417 Ki 0.68 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O[C@H](CC(=O)O)C(=O)O CHEMBL3642937 Ki 0.68 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(C)(C)C(=O)O CHEMBL3667884 Ki 0.69 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCC(=O)NCC(=O)O CHEMBL3672889 Ki 0.69 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@H](CC(=O)O)C(=O)O)s2)c(F)c1 CHEMBL4110371 Ki 0.69 nM
N=C(N)c1ccc(OC(=O)c2cc3c(s2)CN(CC(=O)O)CC3)c(F)c1 CHEMBL3929534 Ki 0.69 nM
N=C(N)Nc1ccc2c(c1)OCCCc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5433360 IC50(app) 0.69 nM
CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642923 Ki 0.7 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642908 Ki 0.71 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CCC(=O)O)(CCC(=O)O)CCC(=O)O CHEMBL3672871 Ki 0.71 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)O)c1 CHEMBL3672878 Ki 0.71 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)cs1)C(=O)O CHEMBL3642967 Ki 0.72 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C(=O)O)c1ccc(O)cc1 CHEMBL3672881 Ki 0.72 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCC(=O)O CHEMBL3920800 Ki 0.72 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](CO)C(=O)O)s2)c(F)c1 CHEMBL3642981 Ki 0.73 nM
N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)N[C@@H](CC(=O)O)C(=O)O)CCCC3)s2)c(F)c1 CHEMBL3667880 Ki 0.73 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C)C(=O)O CHEMBL3667905 Ki 0.73 nM
C=CCN(CC(=O)O)C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3642954 Ki 0.75 nM
CC(C)[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3912993 Ki 0.75 nM
C=CCN(CC(=O)N[C@@H](CC(=O)O)C(=O)O)C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3943096 Ki 0.77 nM
C=CCN(CC(=O)O)C(=O)[C@@H]1CCCN1Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3976398 Ki 0.78 nM
CC(C)[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3907536 Ki 0.78 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642941 Ki 0.79 nM
CC(C)[C@H](NC(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667887 Ki 0.79 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CCC[C@@H](C(=O)O)C1 CHEMBL4113880 Ki 0.81 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)cc2)c(F)c1 CHEMBL5189108 IC50(app) 0.81 nM
CCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642880 Ki 0.82 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)o2)cc1 CHEMBL3951001 Ki 0.82 nM
N=C(N)Nc1ccc(C(=O)Oc2cccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)c2)cc1 CHEMBL5202756 IC50(app) 0.82 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2[N+](=O)[O-])s1)C(=O)O CHEMBL3642895 Ki 0.84 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)C(C)O CHEMBL3667893 Ki 0.84 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cccc(S(=O)(=O)O)c1 CHEMBL3893916 Ki 0.84 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@H]1C(=O)O CHEMBL3667886 Ki 0.87 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)SC(CC(=O)O)C(=O)O CHEMBL3642938 Ki 0.88 nM
CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3642964 Ki 0.88 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N(C)CC(=O)O CHEMBL3667899 Ki 0.88 nM
CC(CCC(=O)N[C@@H](CC(=O)O)C(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1 CHEMBL3642966 Ki 0.89 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC[C@H](C(=O)O)C1 CHEMBL3949541 Ki 0.9 nM
CC(C)C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3898510 Ki 0.9 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCC(=O)O CHEMBL3667908 Ki 0.94 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](CO)C(=O)O CHEMBL3667890 Ki 0.94 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3891228 Ki 0.94 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(N)=O)C(=O)O CHEMBL3642874 Ki 0.95 nM
CC(C)C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642943 Ki 0.95 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642955 Ki 0.95 nM
N=C(N)c1ccc(OC(=O)c2ccc(CN3CCC[C@@H]3C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O)s2)cc1 CHEMBL3905647 Ki 0.95 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)c1ccccc1 CHEMBL3672850 Ki 0.96 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C(=O)O)c1ccccc1 CHEMBL3672851 Ki 0.97 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C1(C(=O)N[C@@H](CC(=O)O)C(=O)O)CCCC1 CHEMBL3971792 Ki 0.97 nM
CCCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642885 Ki 0.98 nM
CC(Cc1csc(C(=O)Oc2ccc(C(=N)N)cc2)c1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642971 Ki 0.98 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCCC(=O)O CHEMBL3639717 Ki 0.98 nM
CN(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)[C@H](Cc1ccccc1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL4112097 Ki 0.98 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCC(=O)O CHEMBL3667892 Ki 0.99 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)co1)C(=O)N[C@@H](CS(=O)(=O)O)C(=O)O CHEMBL3642930 Ki 1.0 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@H]1C(=O)O CHEMBL3667895 Ki 1.0 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@@H]1C(=O)O CHEMBL3667900 Ki 1.0 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(C(=O)O)C1 CHEMBL3959399 Ki 1.0 nM
C=CCN(CC(=O)O)C(=O)[C@@H]1CSCN1Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3897433 Ki 1.0 nM
CC(C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3982871 Ki 1.0 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC[C@@H](C(=O)O)C1 CHEMBL3667911 Ki 1.02 nM
CC[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](CCC(=O)O)C(=O)O CHEMBL3642881 Ki 1.03 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(C(=O)O)cc1 CHEMBL3667909 Ki 1.08 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCP(=O)(O)O CHEMBL3642921 Ki 1.1 nM
CCC[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642944 Ki 1.1 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O CHEMBL3667894 Ki 1.1 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CC[C@@H](C(=O)O)CC1 CHEMBL3672882 Ki 1.11 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CC1 CHEMBL3672891 Ki 1.12 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1C[C@H]1C(=O)O CHEMBL3672874 Ki 1.13 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)O CHEMBL3642858 Ki 1.15 nM
CCC[C@H](NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667907 Ki 1.18 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1nnn[nH]1 CHEMBL3672893 Ki 1.2 nM
N=C(N)Nc1ccc(C(=O)Oc2cccc(C3=NO[C@](CC(=O)O)(C(=O)O)C3)c2)cc1 CHEMBL5175180 IC50(app) 1.2 nM
COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)s2)cc(C(=O)OC)c1 CHEMBL3672873 Ki 1.22 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O CHEMBL3667896 Ki 1.24 nM
N=C(N)c1ccc(OC(=O)c2ccc(CNC3(C(=O)N[C@@H](CC(=O)O)C(=O)O)CC3)s2)c(F)c1 CHEMBL3958604 Ki 1.27 nM
CC(C)CCNC(=O)C(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642914 Ki 1.3 nM
C=CCN(CC(=O)O)C(=O)CCc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 CHEMBL3642920 Ki 1.3 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CC=CC[C@H]1C(=O)O CHEMBL4113254 Ki 1.3 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC(C(=O)O)CC1 CHEMBL3667904 Ki 1.33 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CCC1 CHEMBL3672892 Ki 1.33 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642900 Ki 1.36 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642860 Ki 1.37 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2[N+](=O)[O-])s1)C(=O)N(CCCO)CC(=O)O CHEMBL3642896 Ki 1.41 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cccc(C(=O)O)c1 CHEMBL3667910 Ki 1.43 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)O CHEMBL3642893 Ki 1.44 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@H](CC(=O)O)C(=O)O CHEMBL3642905 Ki 1.47 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCCO)CC(=O)O CHEMBL3642862 Ki 1.49 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H]1CC[C@H](C(=O)O)CC1 CHEMBL3672890 Ki 1.53 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)C(C)C CHEMBL3667891 Ki 1.56 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCC[C@H]1CC(=O)O CHEMBL3672854 Ki 1.58 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3cccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)c3)o2)cc1 CHEMBL3642936 Ki 1.6 nM
N=C(N)Nc1ccc(C(=O)Oc2cccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)c2)cc1 CHEMBL5182597 IC50(app) 1.6 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CCC(=O)O)C(=O)O CHEMBL3642867 Ki 1.63 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3672855 Ki 1.69 nM
N=C(N)Nc1ccc2c(c1)CCCCOc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5418103 IC50(app) 1.7 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1C[C@@H]1C(=O)O CHEMBL3672867 Ki 1.76 nM
N=C(N)Nc1ccc(C(=O)Oc2cccc(C3=NO[C@@](CC(=O)O)(C(=O)O)C3)c2)cc1 CHEMBL5179372 IC50(app) 1.8 nM
C=CCN(CCS(=O)(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667901 Ki 1.81 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](C(=O)O)C(C)O CHEMBL3642868 Ki 1.88 nM
C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3642876 Ki 1.9 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCc1ccccc1 CHEMBL3642913 Ki 1.9 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1CCC[C@@H]1C(=O)O CHEMBL3642871 Ki 1.91 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCC(=O)O CHEMBL3642857 Ki 1.97 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CC(N)=O)C(=O)O CHEMBL3642875 Ki 2.0 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NCP(=O)(O)O CHEMBL3642956 Ki 2.0 nM
C[C@@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CCC(N)=O)C(=O)O CHEMBL3642877 Ki 2.1 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)co1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642927 Ki 2.1 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N(CCCO)CCS(=O)(=O)O CHEMBL3642894 Ki 2.15 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc3)o2)cc1 CHEMBL3642933 Ki 2.2 nM
CC(C)C[C@H](Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642942 Ki 2.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCCC(C(=O)O)C1 CHEMBL3642950 Ki 2.2 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NCC(=O)O CHEMBL3642897 Ki 2.21 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642856 Ki 2.27 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(CC(=O)O)cc1 CHEMBL3672861 Ki 2.41 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccccc1C(=O)O CHEMBL3672885 Ki 2.41 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCC(=O)O CHEMBL3642869 Ki 2.43 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1CCCC(C(=O)O)C1 CHEMBL3642918 Ki 2.5 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)co1)C(=O)NCP(=O)(O)O CHEMBL3642929 Ki 2.5 nM
CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1 CHEMBL3642963 Ki 2.5 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(F)nc1 CHEMBL3672868 Ki 2.51 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1C[C@H](O)C[C@@H]1C(=O)O CHEMBL3642872 Ki 2.54 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H]1COC(=O)C1 CHEMBL3667912 Ki 2.56 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@H](C(=O)O)C1CCCCC1 CHEMBL3667913 Ki 2.56 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NN(CC(=O)O)CC(=O)O CHEMBL3642939 Ki 2.6 nM
CCCN(CC(=O)O)C(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3667898 Ki 2.61 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCC(=O)O CHEMBL3642859 Ki 2.68 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1ccc(C(=O)O)cc1 CHEMBL3672866 Ki 2.69 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)NCP(=O)(O)O)cc3)o2)cc1 CHEMBL3642935 Ki 2.7 nM
CCCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642949 Ki 2.8 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCC#N CHEMBL3672875 Ki 2.9 nM
N=C(N)Nc1ccc2c(c1)CCCCCc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5398070 IC50(app) 2.9 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc3)s2)c(F)c1 CHEMBL3642973 Ki 3.0 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCCO)CC(=O)O CHEMBL3642863 Ki 3.17 nM
N=C(N)c1ccc(OC(=O)c2ccc(CCC(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)O)s2)c(F)c1 CHEMBL3642980 Ki 3.2 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc2)cc1 CHEMBL5200092 IC50(app) 3.2 nM
N=C(N)Nc1ccc2c(c1)CCCCc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5428323 IC50(app) 3.2 nM
CCC(C)[C@H](CC(=O)O)NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3957967 Ki 3.26 nM
CCC(C)[C@@H](CC(=O)O)NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3672862 Ki 3.26 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCCO)CCC(=O)O CHEMBL3642865 Ki 3.31 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CCc2ccc(C(=O)O)cc2C1 CHEMBL3672863 Ki 3.46 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N[C@H](C(=O)O)C(C)O CHEMBL3642866 Ki 3.52 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(O)c(C(=O)O)c1 CHEMBL3892801 Ki 3.52 nM
CC(Cc1ncc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642982 Ki 3.7 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)OC)c1 CHEMBL3672879 Ki 3.73 nM
COc1ncccc1NC(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 CHEMBL3672864 Ki 3.75 nM
COc1ccc(NC(=O)C(C)(C)Cc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)s2)cn1 CHEMBL3672858 Ki 4.13 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCO CHEMBL3642916 Ki 4.4 nM
Cc1c(OC(=O)c2ccc(NC(=N)N)cc2)cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL5407739 IC50(app) 4.4 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)NCC(=O)O)cc3)o2)cc1 CHEMBL3642934 Ki 4.7 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N[C@@H](C(=O)O)C1CCCCC1 CHEMBL3667914 Ki 4.7 nM
CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2)cs1)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3642969 Ki 4.8 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1C[C@@H](O)C[C@H]1C(=O)O CHEMBL3642873 Ki 4.81 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N1CCCC1 CHEMBL3642917 Ki 4.9 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCCCC(=O)O CHEMBL3672883 Ki 4.97 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(F)(F)C1 CHEMBL3672859 Ki 5.27 nM
CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCC[C@H](N)C(=O)O CHEMBL3672865 Ki 5.53 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)cc2)c(Cl)c1 CHEMBL5182234 IC50(app) 5.6 nM
C/C(=C\c1nc(C(=O)Oc2ccc(C(=N)N)cc2)cs1)C(=O)N(CCCO)CC(=O)O CHEMBL3642940 Ki 5.67 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N[C@@H](CO)C(=O)O CHEMBL3642892 Ki 5.72 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)cc2)cc1 CHEMBL5195621 IC50(app) 5.9 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc[nH]c1=O CHEMBL3672853 Ki 6.66 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CCO)Cc1ccccc1 CHEMBL3642864 Ki 6.73 nM
CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cccnc1 CHEMBL3672852 Ki 7.56 nM
CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCCN(C)C CHEMBL3642915 Ki 7.6 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3c(c2)OC[C@@H]3CC(=O)N[C@@H](CC(=O)O)C(=O)O)cc1 CHEMBL5170585 IC50(app) 7.7 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CCC(=O)O)C(=O)O)cc2)cc1 CHEMBL5170208 IC50(app) 7.9 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)s3)s2)cc1 CHEMBL3642975 Ki 8.2 nM
C/C(=C\c1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NCC(=O)O CHEMBL3642891 Ki 9.29 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc3)s2)cc1 CHEMBL3642972 Ki 9.5 nM
N=C(N)c1ccc(OC(=O)c2ccc(-c3cccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)c3)s2)cc1 CHEMBL3642974 Ki 9.8 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3c(c2)OC(CC(=O)N[C@@H](CC(=O)O)C(=O)O)C3)cc1 CHEMBL5169835 IC50(app) 14.0 nM
N=C(N)Nc1ccc2c(c1)CCCc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5413614 IC50(app) 22.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(N)=O)C(=O)O)cc2)cc1 CHEMBL5202535 IC50(app) 23.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)NCC(=O)O)cc2)cc1 CHEMBL5173692 IC50(app) 30.0 nM
Cc1cc(NC(=N)N)ccc1C(=O)Oc1ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)cc1 CHEMBL5182789 IC50(app) 54.0 nM
N=C(N)Nc1ccc2c(c1)CCCCCCc1c(cccc1C(=O)N[C@@H](CC(=O)O)C(=O)O)OC2=O CHEMBL5418493 IC50(app) 81.0 nM
Cc1cc(OC(=O)c2ccc(NC(=N)N)cc2)no1 CHEMBL5190122 IC50(app) 140.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccccc2)cc1 CHEMBL5205880 IC50(app) 400.0 nM
Cc1cc(C(=O)Oc2ccc(CC(=O)N[C@@H](CC(=O)O)C(=O)O)cc2)ccc1NC(=N)N CHEMBL5188778 IC50(app) 680.0 nM
Cc1ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)cc1OC(=O)c1ccc(NC(=N)N)cc1 CHEMBL5401618 IC50(app) 710.0 nM