CNc1cc(Oc2c(Cl)cc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2Cl)ncn1 CHEMBL4869303 Ki 0.54 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]cc(Br)c23)c1 CHEMBL3613198 IC50 0.7 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]cc(C)c23)c1 CHEMBL3613197 IC50 1.6 nM
CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]cc(Br)c23)c1 CHEMBL3613305 IC50 6.3 nM
CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]cc(C)c23)c1 CHEMBL3613199 IC50 7.9 nM
CNc1cc(Oc2c(C)cc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2C)ncn1 CHEMBL4868757 IC50 7.9 nM
CCS(=O)(=O)c1ccc(S(=O)(=O)NC)cc1Nc1cc(Nc2ccc(Cl)cn2)ncn1 CHEMBL4094739 IC50 8.0 nM
CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]c(-c4cccc(C(F)(F)F)c4)cc23)c1 CHEMBL3613309 IC50 10.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)cc(OC)c23)c1 CHEMBL3814834 IC50 10.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc(Nc3ccc(Cl)cc3)n2)c1 CHEMBL3911058 IC50 10.0 nM
CNS(=O)(=O)c1ccc(N(C)CC(F)(F)F)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3984331 IC50 10.0 nM
O=C(O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ncn2)c1 CHEMBL4875220 IC50 10.0 nM
O=C(Nc1ccc(Oc2cc(Nc3cccc(CN4CCCC4)c3)ncn2)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4867760 IC50 10.0 nM
Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1 CHEMBL5416410 Kd 11.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4ccccc4C)cc23)c1 CHEMBL3613185 IC50 13.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4cccc(C)c4)cc23)c1 CHEMBL3613186 IC50 13.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4ccc(C)cc4)cc23)c1 CHEMBL3613187 IC50 13.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4ccc(O)cc4)cc23)c1 CHEMBL3613189 IC50 13.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]c(-c4cccc(C(F)(F)F)c4)cc23)c1 CHEMBL3613307 IC50 13.0 nM
CCOc1cc2ncnc(Nc3cc(S(=O)(=O)NC)ccc3OCC(F)(F)F)c2cc1OC CHEMBL3814998 IC50 13.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3cc(OCCCN4CCOCC4)ccc23)c1 CHEMBL3813957 IC50 13.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3cc(OC)cc(OC)c23)c1 CHEMBL3813948 IC50 13.0 nM
CNS(=O)(=O)c1ccc(N2CCCCC2)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3952704 IC50 13.0 nM
CNS(=O)(=O)c1ccc(S(C)(=O)=O)c(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 CHEMBL4074231 IC50 13.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccn(C)c23)c1 CHEMBL3814010 IC50 16.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]cnc23)c1 CHEMBL3920011 IC50 16.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3913963 IC50 16.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(C(F)(F)F)cn3)ncn2)c1 CHEMBL4102182 IC50 16.0 nM
O=C(Nc1ccc(Oc2ncnc3[nH]ccc23)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4869054 IC50 16.0 nM
Nc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4849349 IC50 16.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4ccncc4)cc23)c1 CHEMBL3613190 IC50 20.0 nM
CNS(=O)(=O)c1ccc(Cl)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3613193 IC50 20.0 nM
CNS(=O)(=O)c1ccc(N2C(C)CCC2C)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3909313 IC50 20.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc(Nc3cccc(C)c3)n2)c1 CHEMBL4066586 IC50 20.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 CHEMBL4061645 IC50 20.0 nM
CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4845883 IC50 20.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)c(F)c2F)ncn1 CHEMBL4857556 IC50 20.0 nM
CNc1cc(Oc2c(F)cc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2F)ncn1 CHEMBL4865373 IC50 20.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4863580 IC50 20.0 nM
COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c2cc1OC CHEMBL4856992 IC50 23.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4ccccc4)cc23)c1 CHEMBL3613184 IC50 25.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1 CHEMBL3815093 IC50 25.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc[nH]c23)c1 CHEMBL3815116 IC50 25.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3cc(OC)c(OC)cc23)c1 CHEMBL3814635 IC50 25.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3cc(OCCCOC)ccc23)c1 CHEMBL3814442 IC50 25.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OCCCOC)ccc23)c1 CHEMBL3814871 IC50 25.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OCCCN4CCOCC4)ccc23)c1 CHEMBL3814923 IC50 25.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3896012 IC50 25.0 nM
CCNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4864463 IC50 25.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2F)ncn1 CHEMBL4066096 IC50 25.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)c3ccccc23)ncn1 CHEMBL4870768 IC50 25.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(Cl)c23)c1 CHEMBL3612665 IC50 32.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(Br)c23)c1 CHEMBL3612666 IC50 32.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccc(CN)cc4)c23)c1 CHEMBL3613181 IC50 32.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccc(N)cc23)c1 CHEMBL3814121 IC50 32.0 nM
CCN(C)c1ccc(S(=O)(=O)NC)cc1Nc1ncnc2[nH]ccc12 CHEMBL3955714 IC50 32.0 nM
CCOc1ccc(S(=O)(=O)NC)cc1Nc1ncnc2[nH]ccc12 CHEMBL3975744 IC50 32.0 nM
CNS(=O)(=O)c1ccc(OC(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3940073 IC50 32.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(C)c3)ncn2)c1 CHEMBL4097027 IC50 32.0 nM
O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4852364 IC50 32.0 nM
CCCNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4877505 IC50 32.0 nM
O=C(Nc1ccc(Oc2cc(NCCO)ncn2)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4871527 IC50 32.0 nM
C[C@H](O)CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4859309 IC50 32.0 nM
CNc1cc(Oc2c(C)cc(NC(=O)Nc3cccc(C(F)(F)F)c3)c3ccccc23)ncn1 CHEMBL4875166 IC50 32.0 nM
CNc1cc(Oc2cc(C)c(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2C)ncn1 CHEMBL4870044 IC50 32.0 nM
CCOc1cc(N2CCN(C)CC2)ccc1Nc1ncc2cc(-c3cccc(NC(=O)c4cccc(C(F)(F)F)c4)c3)c(=O)n(C[C@H]3CCCO3)c2n1 CHEMBL5415503 Kd 39.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(C)c23)c1 CHEMBL3612661 IC50 40.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccccc4)c23)c1 CHEMBL3612667 IC50 40.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccccc4Cl)c23)c1 CHEMBL3613176 IC50 40.0 nM
CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3613196 IC50 40.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]c(Br)cc23)c1 CHEMBL3613306 IC50 40.0 nM
CNc1ccc2c(Nc3cc(S(=O)(=O)NC)ccc3N(C)C)ncnc2c1 CHEMBL3813872 IC50 40.0 nM
CNS(=O)(=O)c1ccc(N(C)CC(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3982684 IC50 40.0 nM
CNS(=O)(=O)c1ccc(N2CCCC(F)(F)C2)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3964799 IC50 40.0 nM
CNS(=O)(=O)c1ccc(O)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3938338 IC50 40.0 nM
CC(C)Nc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4873406 IC50 40.0 nM
CC(C)(O)CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4854957 IC50 40.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(C)(F)F)c3)cc2)ncn1 CHEMBL4868391 IC50 40.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(C)(C)C)c3)cc2)ncn1 CHEMBL4850780 IC50 40.0 nM
CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 CHEMBL386051 Kd 47.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]ncc23)c1 CHEMBL3612646 IC50 50.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccc(OC)cc4)c23)c1 CHEMBL3613179 IC50 50.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(Br)cc23)c1 CHEMBL3613183 IC50 50.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3613195 IC50 50.0 nM
CNc1ccc2ncnc(Nc3cc(S(=O)(=O)NC)ccc3N(C)C)c2c1 CHEMBL3813902 IC50 50.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3[nH]c4ccccc4c23)c1 CHEMBL3957440 IC50 50.0 nM
CCOc1ccc(S(=O)(=O)NC)cc1Nc1cc(Nc2ccc(Cl)cc2)ncn1 CHEMBL3956165 IC50 50.0 nM
CNS(=O)(=O)c1ccc(OC)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3973875 IC50 50.0 nM
CNS(=O)(=O)c1ccc(OC(F)(F)F)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3948684 IC50 50.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc(Nc3ccc(Cl)cc3)n2)c1 CHEMBL4064225 IC50 50.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(C(C)C)c3)ncn2)c1 CHEMBL4084208 IC50 50.0 nM
O=C(Nc1ccc(Oc2ccncc2)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL1233853 IC50 50.0 nM
CNc1nccc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)n1 CHEMBL4861519 IC50 50.0 nM
CC(C)CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4865829 IC50 50.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2Cl)ncn1 CHEMBL4874491 IC50 50.0 nM
CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CHEMBL428690 Kd 55.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4cccc(Cl)c4)c23)c1 CHEMBL3613177 IC50 63.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4cccc(C(F)(F)F)c4)cc23)c1 CHEMBL3613188 IC50 63.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(N)ccc23)c1 CHEMBL3814727 IC50 63.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3cc(OC)c(OC)c(OC)c23)c1 CHEMBL3814097 IC50 63.0 nM
CCN(C)c1ccc(S(=O)(=O)NC)cc1Nc1cc(Nc2ccc(Cl)cc2)ncn1 CHEMBL3954018 IC50 63.0 nM
CNS(=O)(=O)c1ccc(N2CCCC2C(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3932178 IC50 63.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccccc3)ncn2)c1 CHEMBL4067114 IC50 63.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(OC)c3)ncn2)c1 CHEMBL4084088 IC50 63.0 nM
CNS(=O)(=O)c1ccc(OC(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 CHEMBL4064580 IC50 63.0 nM
O=C(Nc1ccc(Oc2ccnc3ccccc23)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4870490 IC50 63.0 nM
C[C@@H](O)CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4847826 IC50 63.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)c(F)c2)ncn1 CHEMBL4863203 IC50 63.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccc(OC)cc23)c1 CHEMBL3813871 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(C(F)(F)F)cc3)ncn2)c1 CHEMBL4102890 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(Cl)c3)ncn2)c1 CHEMBL4062372 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3915155 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(C)cc3)ncn2)c1 CHEMBL4103931 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(S(C)(=O)=O)cc3)ncn2)c1 CHEMBL4083270 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(S(=O)(=O)NC)c3)ncn2)c1 CHEMBL4105656 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(Br)c3)ncn2)c1 CHEMBL4094583 IC50 79.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3894005 IC50 79.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ccn1 CHEMBL1992306 IC50 79.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(C)F)c3)cc2)ncn1 CHEMBL4850964 IC50 79.0 nM
CNc1cc(Oc2c(C)cc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2Cl)ncn1 CHEMBL4856606 IC50 79.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]ccc23)c1 CHEMBL3612647 IC50 80.0 nM
CNS(=O)(=O)c1ccc(N2C(C)CCC2C)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3912429 IC50 80.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccc(Cl)cc4)c23)c1 CHEMBL3613178 IC50 100.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccncc4)c23)c1 CHEMBL3613180 IC50 100.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccc(C(=O)O)cc4)c23)c1 CHEMBL3613182 IC50 100.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c4ccccc4c23)c1 CHEMBL3613191 IC50 100.0 nM
CNS(=O)(=O)c1ccc(OC)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3964772 IC50 100.0 nM
COc1ccc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)c2c1 CHEMBL4868251 IC50 100.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)F)c3)cc2)ncn1 CHEMBL4867053 IC50 100.0 nM
CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 CHEMBL1336 IC50 100.0 nM
CCc1cc(NC(=O)Nc2cccc(C(F)(F)F)c2)cc(Cl)c1Oc1cc(NC)ncn1 CHEMBL4867552 IC50 100.0 nM
C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl CHEMBL601719 Kd 110.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cnc23)c1 CHEMBL3612641 Kd 111.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(C(C)C)c23)c1 CHEMBL3612662 IC50 126.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(CC(C)C)c23)c1 CHEMBL3612663 IC50 126.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(F)c23)c1 CHEMBL3612664 IC50 126.0 nM
CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]c(Br)cc23)c1 CHEMBL3613308 IC50 126.0 nM
COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 CHEMBL1230609 Kd 130.0 nM
CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2ncnc3cc(OC(C)C)c(OC)cc23)c1 CHEMBL3814685 IC50 130.0 nM
CNS(=O)(=O)c1ccc(N2CCC(F)(F)C2)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3904479 IC50 130.0 nM
CNS(=O)(=O)c1ccc(N2CCCC2C)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3912907 IC50 130.0 nM
CNS(=O)(=O)c1ccc(Cl)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3940816 IC50 130.0 nM
CNS(=O)(=O)c1ccc(SC)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3924164 IC50 130.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(C(=O)O)cc23)c1 CHEMBL3612079 IC50 160.0 nM
CNS(=O)(=O)c1ccc(O)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3983781 IC50 160.0 nM
CNS(=O)(=O)c1ccc(C)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3903801 IC50 160.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(OC)cc3)ncn2)c1 CHEMBL4073726 IC50 160.0 nM
O=C(Nc1ccc(Oc2ccncn2)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4856623 IC50 160.0 nM
Cc1cc(Oc2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)ncn1 CHEMBL4872243 IC50 160.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 170.0 nM
COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl CHEMBL288441 Kd 170.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccccc23)c1 CHEMBL3814179 IC50 200.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccsc23)c1 CHEMBL3814515 IC50 200.0 nM
CNS(=O)(=O)c1ccc(F)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3912821 IC50 200.0 nM
CNS(=O)(=O)c1ccc(-c2ccccc2)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3905097 IC50 200.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(S(C)(=O)=O)c3)ncn2)c1 CHEMBL4100539 IC50 200.0 nM
CCc1cccc(NC(=O)Nc2ccc(Oc3cc(NC)ncn3)cc2)c1 CHEMBL4870079 IC50 200.0 nM
CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc21 CHEMBL572881 Kd 220.0 nM
CN(C)CCCN1CCc2c(sc3ncnc(Nc4ccc(N(C)C)c(NC(=O)c5ccco5)c4)c23)C1 CHEMBL4797743 IC50 240.0 nM
CNS(=O)(=O)c1cncc(Nc2ncnc3[nH]ccc23)c1 CHEMBL3612660 IC50 250.0 nM
CNS(=O)(=O)c1ccc(N2CCCC2C)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3915737 IC50 250.0 nM
CNS(=O)(=O)c1ccc(F)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3896147 IC50 250.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 310.0 nM
CNS(=O)(=O)c1ccc(N2CCCC2)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3960270 IC50 320.0 nM
CN1CCN(CCCN2CCc3c(sc4ncnc(Nc5ccc(N(C)C)c(NC(=O)c6cccs6)c5)c34)C2)CC1 CHEMBL4796030 IC50 330.0 nM
Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc(C(F)(F)F)c2)cn1 CHEMBL255863 Kd 360.0 nM
CNS(=O)(=O)c1cccc(Nc2ncnc3c2CC(=O)N3)c1 CHEMBL3612650 IC50 400.0 nM
CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccc(Cl)cc23)c1 CHEMBL3952136 IC50 400.0 nM
CNS(=O)(=O)c1ccc(SC)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3948258 IC50 400.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(C(C)(C)C)c3)ncn2)c1 CHEMBL4076602 IC50 400.0 nM
CNc1cc(Oc2ccc(NC(=O)Nc3cccc(CF)c3)cc2)ncn1 CHEMBL4859818 IC50 400.0 nM
CCC(=O)Nc1cc(Nc2ncnc3sc4c(c23)CCN(CCCN2CCOCC2)C4)ccc1N(C)C CHEMBL4786692 IC50 480.0 nM
CNS(=O)(=O)c1ccc(C)c(Nc2ncnc3[nH]cnc23)c1 CHEMBL3612657 IC50 500.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc([N+](=O)[O-])c3)ncn2)c1 CHEMBL4065426 IC50 500.0 nM
CN1CCc2c(sc3ncnc(Nc4ccc(N(C)C)c(NC(=O)c5ccco5)c4)c23)C1 CHEMBL4776450 IC50 560.0 nM
C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 CHEMBL553 Kd 570.0 nM
CN(C)CCCN1CCc2c(sc3ncnc(Nc4ccc(N(C)C)c(NC(=O)c5cccs5)c4)c23)C1 CHEMBL4795178 IC50 570.0 nM
CNS(=O)(=O)c1ccc(C)c(Nc2ncnc3[nH]ccc23)c1 CHEMBL3613192 IC50 630.0 nM
CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccccc3F)ncn2)c1 CHEMBL4065137 IC50 630.0 nM
CNS(=O)(=O)c1cccc(Nc2ccnc(Nc3cccc(C)c3)n2)c1 CHEMBL4077229 IC50 630.0 nM
CN1CCN(CCCN2CCc3c(sc4ncnc(Nc5ccc(N(C)C)c(NC(=O)c6ccco6)c5)c34)C2)CC1 CHEMBL4793408 IC50 640.0 nM
CN(C)c1ccc(Nc2ncnc3sc4c(c23)CCNC4)cc1NC(=O)c1ccco1 CHEMBL4792239 IC50 730.0 nM
CN(C)c1ccc(Nc2ncnc3sc4c(c23)CCNC4)cc1NC(=O)c1cccs1 CHEMBL4781587 IC50 780.0 nM
CNS(=O)(=O)c1ccc(N)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3920887 IC50 800.0 nM
CNc1cc(Nc2cccc(S(=O)(=O)NC)c2)ncn1 CHEMBL4084939 IC50 800.0 nM
O=C(Nc1ccc(Oc2ncnc3ccccc23)cc1)Nc1cccc(C(F)(F)F)c1 CHEMBL4857725 IC50 800.0 nM
CN(C)c1ccc(Nc2ncnc3sc4c(c23)CCN(C(=O)c2ccccn2)C4)cc1NC(=O)c1ccco1 CHEMBL4792676 IC50 820.0 nM
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL4465866 Kd 844.0 nM
CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 CHEMBL1241674 Kd 880.0 nM
CN(C)c1ccc(Nc2ncnc3sc4c(c23)CCNC4)cc1NC(=O)c1ccncc1 CHEMBL4789876 IC50 960.0 nM
CN(C)c1ccc(Nc2ncnc3sc4c(c23)CCN(C(=O)c2ccncc2)C4)cc1NC(=O)c1ccco1 CHEMBL4785969 IC50 980.0 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 1000.0 nM
CNS(=O)(=O)c1ccc(N2CCC(F)(F)C2)c(Nc2cc(Nc3ccc(Cl)cc3)ncn2)c1 CHEMBL3937137 IC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM