COc1ccc(-c2c3c(cc4cc5c(cc24)OCO5)C(=O)OC3)cc1OC CHEMBL440125 IC50 0.21 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N2CCO[C@H](OC)C2)[C@H](O)[C@H](C)O1 CHEMBL1232279 IC50 1.5 nM
CC(=O)[C@]1(O)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@H](N)[C@H](O)[C@H](C)O2)C1)C(=O)c1ccccc1C3=O CHEMBL1117 IC50 2.6 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@@H](O)[C@H](C)O1 CHEMBL417 IC50 3.0 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 CHEMBL53463 IC50 4.9 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(C)=O)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 CHEMBL178 IC50 10.0 nM
N[C@@H]1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2Oc2c-4ccc3c2ccc2ccccc23)C1 CHEMBL346068 IC50 60.0 nM
CC[C@@](C)(Nc1ccnc(-c2c[nH]c3ncccc23)n1)C(=O)NCC(F)(F)F CHEMBL3039513 Kd apparent 64.0 nM
CCC(=O)NCCC1=C(SC)C(=O)c2nccc3c2c1nc1ccccc13 CHEMBL2296491 IC50 76.0 nM
COc1cc(CCNC(=O)C=C(C)C)c2c3c(ccnc13)-c1ccccc1N2 CHEMBL2296492 IC50 125.0 nM
COC1=C(CCNC(C)=O)c2nc3ccccc3c3ccnc(c23)C1=O CHEMBL2296490 IC50 132.0 nM
CC(=O)Nc1ccc2c(-c3cc4ccccc4o3)ccnc2c1O CHEMBL4463643 IC50 200.0 nM
COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNCCCl)c(OC)c2)ccc1OC(=O)CNCCCl CHEMBL2260090 IC50 350.0 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 IC50 390.0 nM
CCN1C[C@]2(COC)[C@H](O)C[C@H](OC)[C@@]34[C@@H]5C[C@@]6(O)[C@H](OC(=O)c7ccccc7)[C@@H]5[C@@](OC(C)=O)([C@@H]([C@H](OC)[C@H]23)[C@@H]14)[C@@H](O)[C@@H]6OC CHEMBL5314360 IC50 400.0 nM
COc1cc([C@@H]2c3cc4c(cc3[C@H](O)[C@H]3COC(=O)[C@@H]23)OCO4)cc(OC)c1OC CHEMBL283120 Kd apparent 486.0 nM
C/C=C(\C)C(=O)C(CNCC=O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 CHEMBL2296496 IC50 592.0 nM
CC(C)=CC(=O)C(CNCC=O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 CHEMBL2296497 IC50 592.0 nM
O=C(CCN1CCOCC1)Nc1ccc2c(-c3cc(F)ccc3O)ccnc2c1O CHEMBL4527023 IC50 600.0 nM
CC(C)(O)CC(=O)C(CNCC=O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 CHEMBL2296494 IC50 639.0 nM
Cc1[nH]c(C(=O)Nc2ccc(C(N)=O)cc2OCc2ccc(C(=O)NCCN)cc2)c(Cl)c1Cl CHEMBL5408150 IC50 670.0 nM
c1ccc2c(c1)nc(NC1CCCCC1)c1nncn12 CHEMBL1305588 IC50 680.0 nM
N[C@H]1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2Oc2c-4ccc3c2ccc2ccccc23)C1 CHEMBL155344 IC50 700.0 nM
CC(=O)Nc1ccc2c(-c3ccc(C(F)(F)F)cc3)ccnc2c1O CHEMBL4552030 IC50 700.0 nM
CCc1nc2nc(Nc3ccc4nc(OCCN5CCOCC5)ccc4c3)nc(NC(C)(C)C)c2[nH]1 CHEMBL5414329 IC50 730.0 nM
COc1cccc(NC(=O)CSc2nnc3c4nncn4c4ccccc4n23)c1 CHEMBL4288104 IC50 850.0 nM
CN(C)CCCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc(C#N)c(C#N)nc21 CHEMBL3759668 IC50 900.0 nM
CCCCCc1ccc(-c2cn(C3COC4=C(Br)C(=O)C(=O)c5cccc3c54)nn2)cc1 CHEMBL2424901 IC50 920.0 nM
O=C(CSc1nnc2c3nncn3c3ccccc3n12)Nc1ccc(F)cc1 CHEMBL4286850 IC50 940.0 nM
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 CHEMBL359744 IC50 940.0 nM
Nc1ccc2c(c1)Oc1c(N3CC[C@H](N)C3)c(F)cc3c(=O)c(C(=O)O)cn-2c13 CHEMBL4064127 IC50 970.0 nM
Cc1cc(C)c(S(=O)(=O)Nc2ccc3c(=O)cc(-c4ccccc4)oc3c2)c(C)c1 CHEMBL4636680 IC50 980.0 nM
NCCCNCC(O)COc1cc(O)c2c(=O)c3ccccc3oc2c1 CHEMBL4061116 IC50 1000.0 nM
O=C(CN1CCOCC1)Nc1ccc2c(-c3cc4ccccc4o3)ccnc2c1O CHEMBL4454056 EC50 1000.0 nM
Cc1[nH]c(C(=O)Nc2ccc(C(N)=O)cc2OCc2cccc(C(=O)NCCN)c2)c(Cl)c1Cl CHEMBL5421247 IC50 1000.0 nM