Cc1ccc(NC(=O)Cc2csc(-c3ccccc3)n2)cc1F CHEMBL1445277 Potency 0.2 nM
COc1ccc(CCNc2nc(SCc3ccccc3F)nc3ccccc23)cc1OC CHEMBL1613036 Potency 0.3 nM
COC(=O)c1cc2sccc2n1Cc1nc(-c2ccc(Cl)cc2)oc1C CHEMBL1488839 Potency 0.6 nM
CCOC(=O)/C(C#N)=C/c1ccc(-c2ccc(C)cc2)o1 CHEMBL1363696 Potency 0.6 nM
CCc1cccc(C)c1NC(=O)CCS(=O)(=O)c1cc(Br)cc2c1N(C(=O)C1CC1)CC2 CHEMBL1322288 Potency 0.7 nM
CN1[C@@H]2CC[C@H]1CC(OC(=O)c1cc(Cl)cc(Cl)c1)C2 CHEMBL1365455 Potency 0.8 nM
N#CC(C#N)=C(N)/C(C#N)=C/c1ccc(O)cc1 CHEMBL76589 Potency 0.8 nM
CCN(CC)S(=O)(=O)c1ccc(-c2cs/c(=N\c3cccc(C(F)(F)F)c3)n2Cc2ccc3c(c2)OCO3)cc1 CHEMBL1552919 Potency 1.1 nM
CCN(CC)C(=O)CSc1nc2ccsc2c(=O)n1Cc1ccccc1Cl CHEMBL1369715 Potency 1.8 nM
CCCCNS(=O)(=O)c1ccc2nc(NC(=O)c3cccnc3)sc2c1 CHEMBL1395891 Potency 2.0 nM
CCCCCCCCOc1ccc(C(=O)O)cc1 CHEMBL1328156 Potency 2.0 nM
CN1CCN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)c2ccccc21 CHEMBL4248974 EC50 2.0 nM
C=C(C)CSc1cc(C)c(C#N)c2nc3ccccc3n12 CHEMBL1586047 Potency 2.2 nM
COc1ccccc1NC(=O)c1c(NC(=O)c2ccco2)sc2c1CCC(C(C)(C)C)C2 CHEMBL1416430 Potency 2.5 nM
Cc1c(Cl)cccc1NC(=O)C1CCCN(c2ncnc3onc(C)c23)C1 CHEMBL1358083 Potency 2.5 nM
CCn1c2c(c(=O)n3ncc(C(=O)N4CCN(c5ccccc5)CC4)c13)CN(Cc1ccc(OC)cc1)CC2 CHEMBL1434616 Potency 2.5 nM
COc1ccc(-c2noc(Cn3c(=O)c4ccccc4n(CC(=O)Nc4cccc(C(F)(F)F)c4)c3=O)n2)cc1 CHEMBL1594990 Potency 2.5 nM
O=C(Cn1cnc2c(nnn2Cc2ccccc2F)c1=O)N1CCN(c2ccccc2)CC1 CHEMBL1503585 Potency 2.5 nM
CCCCCOc1ccc(/C=C/C(=O)Nc2sc(C)c(C)c2C(=O)OCC)cc1OC CHEMBL1560327 Potency 2.5 nM
CCN(CC)CCCNC(=O)CCCn1ncn2c(cc3occc32)c1=O CHEMBL1554996 Potency 2.8 nM
CCOc1cc(C(=O)Nc2ccc(-c3nc4ccccc4s3)cc2Cl)cc(OCC)c1OCC CHEMBL1395568 Potency 2.8 nM
CCOC(=O)c1cnn(-c2ccc(C(=O)Nc3cccc(C(C)=O)c3)cc2)c1N CHEMBL1521547 Potency 2.8 nM
COc1cccc(-c2nc(S(=O)(=O)c3ccc(C)cc3)c(NCc3ccccc3)o2)c1 CHEMBL1315739 Potency 2.8 nM
CCCCOc1ccc(NC(=O)c2cc3c(n(-c4ccc(Cl)cc4)c2=O)CCCC3=O)cc1 CHEMBL1596375 Potency 2.8 nM
Cc1ccc([S+]([O-])Cc2ccc(C(=O)NC3CCCCCC3)o2)cc1 CHEMBL1479897 Potency 2.8 nM
Cc1ccc(C)c(NC(=O)C(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)c2ccccc2)c1 CHEMBL1315838 Potency 2.8 nM
COc1ccccc1NC(=O)N1CCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)CC1 CHEMBL1489788 Potency 3.2 nM
CCOC(=O)c1c(N)n(-c2ccc(C)c(Cl)c2)c2nc3ccccc3nc12 CHEMBL1573918 Potency 3.2 nM
COc1cccc(-c2nc(C[S+]([O-])CC(=O)N3CCN(c4cccc(C(F)(F)F)c4)CC3)c(C)o2)c1 CHEMBL1435124 Potency 3.2 nM
CC1CCCC(C)N1S(=O)(=O)c1ccc(S(=O)(=O)NCCc2ccncc2)cc1 CHEMBL1390057 Potency 3.2 nM
Cc1ccc(Cl)cc1-n1ncc2c(NCCCn3ccnc3)ncnc21 CHEMBL1611610 Potency 3.2 nM
Cc1cccc(NC(=O)C2C3C=CC(C4CC34)C2C(=O)O)c1 CHEMBL1524880 Potency 3.2 nM
Cc1c(C(=O)N(C)C)sc2c1c(=O)n(-c1ccc(Cl)c(Cl)c1)c(=O)n2CC(=O)Nc1cccc(C(F)(F)F)c1 CHEMBL1591945 Potency 3.2 nM
Cc1nn(CC(=O)NCCc2ccc(Cl)cc2Cl)c(C)c1[N+](=O)[O-] CHEMBL1447409 Potency 3.2 nM
CC(=O)c1cccc(NC(=O)Nc2cc3c(cc2N2CCCC2)n(C)c(=O)n3C)c1 CHEMBL1489584 Potency 3.2 nM
COc1ccc(NC(=O)CSc2nc3c4ccccc4nc-3c(O)n2C)cc1 CHEMBL1585613 Potency 3.2 nM
Cc1nc2c(C(=O)NCc3ccccc3Cl)cnn2c(C)c1Cc1ccccc1 CHEMBL1357224 Potency 3.2 nM
Cc1ccc2nc(-c3ccc(NC(=O)c4ccccc4S(C)(=O)=O)cc3)sc2c1 CHEMBL1591715 Potency 3.2 nM
COc1ccc(CNc2ccc3cc(S(=O)(=O)N4CCCCC4)ccc3n2)cc1 CHEMBL1355215 Potency 3.2 nM
CC1CCN(S(=O)(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)CC1 CHEMBL1315271 Potency 3.2 nM
O=C(NCCc1ccc(Cl)cc1)c1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)c1ccccc1S2(=O)=O CHEMBL1591162 Potency 3.2 nM
Cc1cccc(CN2C(=O)CN=C(c3ccccc3)c3cc(Cl)ccc32)c1 CHEMBL1520707 Potency 3.2 nM
CCOc1ccc2c(C)nc(NC3=NC(C)=CC(C)(C)N3)nc2c1 CHEMBL1528359 Potency 3.2 nM
COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccc(N(C)S(C)(=O)=O)cc3)cc2)cc1 CHEMBL1455974 Potency 3.2 nM
COc1cc2c(cc1NC(=O)COc1ccc(Br)cc1)oc1ccccc12 CHEMBL1551999 Potency 3.2 nM
Cc1ccc(NC(=O)c2cccc(N3CCCS3(=O)=O)c2)cc1C CHEMBL1554992 Potency 3.2 nM
Cn1c(SCC(=O)Nc2ccccc2)nnc1-c1ccccc1 CHEMBL1371440 Potency 3.2 nM
CCOC(=O)C(CC)Sc1[nH]cnc2ncnc1-2 CHEMBL1360924 Potency 3.2 nM
Cc1cccc(NC(=O)CSc2nc(C)c(Cc3ccccc3)c(=O)[nH]2)c1C CHEMBL1405361 Potency 3.2 nM
CNC(=O)CSc1nnc(NC(=O)Nc2ccccc2)s1 CHEMBL1513877 Potency 3.2 nM
O=C(NCc1ccccc1Cl)c1ccc(CSCc2cccc(F)c2)o1 CHEMBL1356157 Potency 3.2 nM
COc1ccccc1NC(=O)NCc1cccn1Cc1ccccc1 CHEMBL1354467 Potency 3.2 nM
CCOc1ccc(CC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1OCC CHEMBL1610235 Potency 3.2 nM
Cc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3)c(=O)n1CC(=O)N1CCCC1)n2C CHEMBL1418224 Potency 3.2 nM
CCOC(=O)c1c(S(=O)(=O)N2CCCC(C(=O)Nc3ncccc3C)C2)c(C)n(C)c1C CHEMBL1410780 Potency 3.2 nM
Cc1ccc(-c2nc(CSc3nnc(C)n4c3cc3occc34)c(C)o2)cc1 CHEMBL1437254 Potency 3.2 nM
CC1CC(=O)N(CC(=O)Nc2ccc(F)cc2F)c2ccccc2S1 CHEMBL1553620 Potency 3.2 nM
COc1cc2c(-c3ccccc3Cl)nc3c(c(C)nn3-c3ccccc3)c2cc1OC CHEMBL1551408 Potency 3.2 nM
C=CCc1cccc2cc(C(=O)Nc3cccc(Cl)c3)c(=O)oc12 CHEMBL1315321 Potency 3.2 nM
COC(=O)c1ccc(NC(=O)c2c(NCc3cccc(F)c3)sc3c2CCCC3)cc1 CHEMBL1536173 Potency 3.2 nM
Nc1c(-c2nc(-c3cccs3)no2)nnn1-c1cccc(Cl)c1 CHEMBL1563230 Potency 3.2 nM
COc1ccc(NC(=O)Cn2cc(C(=O)c3cccs3)c3ccccc32)cc1 CHEMBL1592621 Potency 3.2 nM
CC(C)NC(=O)c1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)c1ccccc1[S+]2[O-] CHEMBL1317654 Potency 3.2 nM
CC(C)c1ccc(NC(=O)C(Cc2ccccc2)NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1 CHEMBL1591101 Potency 3.2 nM
CCOc1ccc(-n2c(=O)c3c4c(sc3n(CC(=O)NC(C)CC)c2=O)CCC4)cc1 CHEMBL1475317 Potency 3.2 nM
COc1ccc(OC)c(CNCc2c(C(=O)O)n(Cc3ccccc3)c3cc(OC)ccc23)c1 CHEMBL1395699 Potency 3.2 nM
N#Cc1ccccc1OCC(=O)N1CCN(c2ccccc2)CC1 CHEMBL1533883 Potency 3.2 nM
CC(C(=O)NCCCN1CCOCC1)n1cccc1C(=O)c1ccccc1 CHEMBL1465065 Potency 3.2 nM
O=C(CC1N=C2c3ccccc3N=C(SCC(=O)Nc3cccc(Cl)c3)N2C1=O)NCc1cccs1 CHEMBL1437506 Potency 3.2 nM
COc1ccc(-n2nc3ccc(NC(=O)c4cccc(OCCC(C)C)c4)cc3n2)cc1 CHEMBL1455472 Potency 3.2 nM
Cc1ccccc1-c1noc(-c2nnn(-c3ccccc3C)c2N)n1 CHEMBL1377271 Potency 3.2 nM
CCc1cccc(C)c1NC(=O)CC1Oc2ccc(C)cc2NC1=O CHEMBL1401147 Potency 3.2 nM
COc1ccc2c(c1)CCc1c(C(=O)Nc3ccc(C#N)cc3)noc1-2 CHEMBL1607045 Potency 3.2 nM
Cc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C2CCCCC2)cc1 CHEMBL1592148 Potency 3.2 nM
Cc1cc(C)c(/C=C/c2onc(C)c2S(=O)(=O)N2CCC(C(=O)Nc3cccc(C)c3C)CC2)c(C)c1 CHEMBL1553327 Potency 3.2 nM
COc1ccc(NC(=O)CC2C(=O)N(c3ccc(C)cc3)C(=O)N2Cc2ccc3c(c2)OCO3)cc1 CHEMBL1354595 Potency 3.2 nM
CCOn1c(=O)c(C)[n+]([O-])c2ccccc21 CHEMBL1596914 Potency 3.2 nM
O=c1c2ccccc2nc(/C=C/c2cccc3ccccc23)n1-c1ccccc1Cl CHEMBL1373990 Potency 3.2 nM
Cc1ccc(-n2c(/C=C\c3ccc(F)cc3)nc3ccccc3c2=O)cc1Cl CHEMBL1476286 Potency 3.2 nM
CCOC(=O)c1c(C)n(-c2ccccc2)c2ccc(OC(=O)c3cccc(OC)c3OC)cc12 CHEMBL1362000 Potency 3.2 nM
CC(C)(C)NC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 CHEMBL1397964 Potency 3.2 nM
CCOC(=O)N1N=C(CC)CC1(O)C(F)(F)F CHEMBL1564752 Potency 3.2 nM
CCCCN(CC)C(=O)CSc1nc2ccccc2c(=O)n1Cc1ccco1 CHEMBL598688 Potency 3.2 nM
COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)Nc2ccc(C)c(C)c2)cc1OC CHEMBL1418311 Potency 3.2 nM
COc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1Cc1cccc(C(F)(F)F)c1)n2C CHEMBL1397275 Potency 3.2 nM
Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1cc(Cl)ccc1C CHEMBL1552916 Potency 3.2 nM
Cc1ccco1 CHEMBL1445555 Potency 3.2 nM
CC(=O)Nc1ccc(-c2nnc3n(Cc4ccc(C)cc4)c(=O)c4ccccc4n23)cc1 CHEMBL1356789 Potency 3.2 nM
Cc1ccc(-n2c(CCC(=O)O)ccc2-c2cccs2)cc1Cl CHEMBL1397396 Potency 3.2 nM
CC(C)(C)C1CCc2c(sc(NC(=O)c3ccccc3F)c2C(=O)NCc2ccco2)C1 CHEMBL1442255 Potency 3.2 nM
CC(C)C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 CHEMBL1514022 Potency 3.2 nM
c1ccc(Nc2cccc3ccccc23)cc1 CHEMBL170408 Potency 3.2 nM
O=C(Nc1ccc2nn(-c3ccccc3)nc2c1)c1ccc(-c2cccc(Cl)c2)o1 CHEMBL1606243 Potency 3.2 nM
Cc1ccc(Cn2c(=O)n(CCCC(=O)NCc3ccccc3Cl)c(=O)c3ccccc32)cc1 CHEMBL1356895 Potency 3.2 nM
CCCNC(=O)Cn1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O CHEMBL1433334 Potency 3.5 nM
COc1ccc(C(C(=O)NC(C)(C)C)N(Cc2cccs2)C(=O)CCC(=O)Nc2cc(C)on2)cc1 CHEMBL1353679 Potency 3.5 nM
Cc1nc2cc(C(=O)NCCC3=CCCCC3)ccc2n1-c1ccc(Br)cc1 CHEMBL1474187 Potency 3.5 nM
CN(C(=O)Nc1ccccc1)C1CCS(=O)(=O)C1 CHEMBL1447096 Potency 3.5 nM
O=C(CCC1N=C2c3ccccc3N=C(SCc3ccccc3F)N2C1=O)NCc1ccc(F)cc1 CHEMBL1367014 Potency 3.5 nM
COc1cc(NC(=O)c2cc(C)nc3c2c(C)nn3-c2ccccc2Cl)cc(OC)c1 CHEMBL1437055 Potency 3.5 nM
CCC(C)NC(=O)Cn1cnc2sc(C)c(S(=O)(=O)N3CCN(c4ccccc4OC)CC3)c2c1=O CHEMBL1565994 Potency 3.5 nM
COc1cccc(-c2nnc(-c3cc4cc(Cl)ccc4oc3=O)o2)c1 CHEMBL1455275 Potency 3.5 nM
CCOC(=O)c1nnn(CC(=O)NC(=O)Nc2ccc(F)cc2)c1C(=O)OCC CHEMBL1324485 Potency 3.5 nM
Cc1cccc(Oc2nc3c(C)cccn3c(=O)c2/C=C(\C#N)c2nc3ccccc3[nH]2)c1 CHEMBL1314513 Potency 3.5 nM
CC(C)(C)c1ccc(-c2nc3cc(NC(=O)c4cccc(Br)c4)ccc3o2)cc1 CHEMBL1553397 Potency 3.5 nM
CS(=O)(=O)N(CC(=O)NCCSCc1ccccc1)c1cc(C(F)(F)F)ccc1Cl CHEMBL1480810 Potency 3.5 nM
CCOc1ccc(CC(=O)NCc2ccc3c(c2)CCN3C(C)=O)cc1OCC CHEMBL1474467 Potency 3.5 nM
CC(C)(C)c1ccc(S(=O)(=O)c2cnc(SCC(=O)Nc3ccc(F)c(Cl)c3)[nH]c2=O)cc1 CHEMBL1433908 Potency 3.5 nM
CCn1c2ccccc2c2cc(CN3CCN(Cc4ccccc4F)CC3)ccc21 CHEMBL1433936 Potency 3.5 nM
COc1cccc2cc(-c3nc(-c4ccccc4F)no3)c(=O)oc12 CHEMBL1434768 Potency 3.5 nM
COc1ccc(NC(=O)c2ccc(-c3nc(CSc4ccccc4)c(C)o3)cc2)c(OC)c1 CHEMBL1602165 Potency 3.5 nM
Cc1cc(-c2ccccc2)nc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3Cl)nn12 CHEMBL1356400 Potency 3.5 nM
CCOC(=O)c1ccc(NC(=O)CSc2nccn2-c2cc(C)cc(C)c2)cc1 CHEMBL1359340 Potency 4.0 nM
CCCOc1ccc(-c2nc(N3CCCCC3)c3ccccc3n2)cc1 CHEMBL1593708 Potency 4.0 nM
CCOC(=O)c1c(NC(=O)COc2cccc(C(F)(F)F)c2)sc2c1CCC(C)C2 CHEMBL1564054 Potency 4.0 nM
CC(=O)Nc1nonc1-c1nnc(SCc2ccccc2F)n1C CHEMBL1338213 Potency 4.0 nM
CCOC(=O)c1c(S(=O)(=O)N2CCC(C(=O)Nc3ncccc3C)CC2)c(C)n(C)c1C CHEMBL1396578 Potency 4.0 nM
COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cc3ccccc3o2)cc1 CHEMBL1552620 Potency 4.0 nM
COc1ccc(-c2nc(SCC(=O)NC3CCCC3)c(-c3ccc(F)cc3)[nH]2)cc1 CHEMBL1394335 Potency 4.0 nM
CCOc1ccc(C(=O)Nc2cccc(NC(=O)c3ccco3)c2)cc1Cl CHEMBL1405551 Potency 4.0 nM
COc1ccc(S(=O)(=O)N(CC(=O)Nc2cccnc2)c2ccc(C)cc2)cc1OC CHEMBL1433447 Potency 4.0 nM
COc1cc(/C=C/c2nc3cc(Cl)ccc3c(=O)n2-c2ccc(C)cc2C)cc(OC)c1OC CHEMBL1402619 Potency 4.0 nM
Cn1ncc2c(NCc3ccc(Cl)cc3)ncnc21 CHEMBL1592555 Potency 4.0 nM
Cc1ccc(C2C=C(c3ccc(Cl)cc3)Nc3nc(NC(=O)c4ccco4)nn32)cc1 CHEMBL1316566 Potency 4.0 nM
CCCCc1ccc(C(=O)N/C(=C\c2ccc(C)cc2)C(=O)NC2CCCCC2)cc1 CHEMBL1407482 Potency 4.0 nM
CCOC(=O)c1cc(C)n(CC2CCC(C(=O)Nc3ccc(OC)c(OC)c3)CC2)c1C CHEMBL1361274 Potency 4.0 nM
Cc1ccc(S(=O)(=O)CC(C)N2CCN(C3CCCCC3)CC2)cc1 CHEMBL1343629 Potency 4.0 nM
COc1ccc(Cl)cc1NC(=O)c1c(NCc2cccs2)sc2c1CCC(C)C2 CHEMBL1408548 Potency 4.0 nM
CCOC(=O)c1c(-c2ccc(C)cc2C)csc1NC(=O)c1ccccc1Cl CHEMBL1314238 Potency 4.0 nM
Cc1cc(NC(=O)c2ccc(F)cc2)ccc1-c1cc2ccccc2oc1=O CHEMBL1604498 Potency 4.0 nM
COc1ccc(C)cc1NC(=O)CSc1nc2ccccc2nc1N1CCOCC1 CHEMBL1530829 Potency 4.0 nM
COc1cc(-c2cc(OC)c3c(C)oc(C)c3c(=O)c2)ccc1OC(=O)c1ccccc1Cl CHEMBL1442272 Potency 4.0 nM
N#CCSc1ncccc1-c1nc2ccccc2[nH]1 CHEMBL1510976 Potency 4.0 nM
CC1Cn2c(C(=O)NCc3cccc(Br)c3)cc3cccc(c32)S1 CHEMBL1354873 Potency 4.0 nM
CSc1cccc(Nc2cc(C(=O)NCCCN(Cc3ccccc3)C(C)C)c3ccccc3n2)c1 CHEMBL1553504 Potency 4.0 nM
Cc1c(C(=O)NCc2ccccc2Cl)sc2nc(-c3ccc(F)cc3)cn12 CHEMBL1472741 Potency 4.0 nM
CCN(c1ccccc1)c1ncnc2c1cnn2-c1ccc(OC)cc1 CHEMBL1401545 Potency 4.0 nM
Cn1c(SCC(N)=O)nc2c([nH]c3ccccc32)c1=O CHEMBL1368498 Potency 4.0 nM
O=C(c1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)c1ccccc1S2(=O)=O)N1CCCC1 CHEMBL1612485 Potency 4.0 nM
CCCOc1ccc(NC(=O)CC2C(=O)N(c3ccc(C)cc3)C(=O)N2Cc2cccc(OC)c2)cc1 CHEMBL1572004 Potency 4.0 nM
CCC(C)OC(=O)/C(C#N)=C\c1ccc(-c2ccccc2Cl)o1 CHEMBL1357680 Potency 4.0 nM
COc1ccc(OC)c(-n2c3c(cc(-c4nc(-c5ccc(Cl)cc5)cs4)c2=O)C(=O)CC(C)(C)C3)c1 CHEMBL1371078 Potency 4.0 nM
Cc1ccc(C2CCN(C(=O)Nc3ccc(C)c(C)c3)C2)cc1 CHEMBL1516425 Potency 4.0 nM
COc1ccccc1CNc1nc2ccccc2c2nc(-c3cccnc3)nn12 CHEMBL1328206 Potency 4.0 nM
CCOc1ccc(Br)cc1CNCCSc1nnnn1-c1ccccc1 CHEMBL1511994 Potency 4.0 nM
O=C(CN1C(=O)COc2ccc(S(=O)(=O)N3CCCC3)cc21)N1CCN(c2ccc(Cl)cc2)CC1 CHEMBL1397165 Potency 4.0 nM
Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 CHEMBL1332323 Potency 4.0 nM
COc1ccc(C(=O)NC(c2ccccc2Cl)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL599100 Potency 4.0 nM
CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)N1CCCC(C(=O)N2CCN(c3ccccc3F)CC2)C1 CHEMBL1359840 Potency 4.0 nM
Cn1c(=O)c(=O)n(C)c2cc(NC(=O)c3cccc(F)c3)c(Cl)cc21 CHEMBL1559936 Potency 4.0 nM
CCOC(=O)c1ccc(Nc2c(-c3cccc(O)c3)nc3[nH]cnn23)cc1 CHEMBL1495210 Potency 4.0 nM
CN(C)c1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 CHEMBL1601419 Potency 4.0 nM
COC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 CHEMBL1409193 Potency 4.0 nM
CCOc1ccc2nc(N3CCCC(C(=O)NCCc4ccc(OCC)c(OCC)c4)C3)sc2c1 CHEMBL1590037 Potency 4.0 nM
Cc1ccc2nc(-c3cccc(NC(=O)CSc4ccc(Cl)cc4)c3)oc2c1 CHEMBL1437584 Potency 4.0 nM
CC(C)n1c(=N)c(C(=O)NCc2ccccc2)cc2c(=O)n3ccccc3nc21 CHEMBL1487391 Potency 4.0 nM
CC(=O)NCC(=O)NC(Cc1ccccc1)C(N)=O CHEMBL1404026 Potency 4.0 nM
Cc1cc(NC(=O)C2CCN(S(=O)(=O)c3cccc4nsnc34)CC2)ccc1Br CHEMBL1553315 Potency 4.0 nM
CCOC(=O)C1=C(C)N=C2SCCC(=O)N2C1c1ccc(OCc2ccccc2)cc1 CHEMBL1355746 Potency 4.0 nM
COc1ccc(Nc2cc(C(=O)NCCc3ccc(C)cc3)c3ccccc3n2)c(OC)c1 CHEMBL1328486 Potency 4.0 nM
c1ccccc1 CHEMBL277500 Potency 4.0 nM
COc1cccc(CNC(=O)CN(c2ccc(C)cc2)S(=O)(=O)N(C)C)c1OC CHEMBL1473518 Potency 4.0 nM
O=C(Cn1nc2c(cc1=O)CCCC2)NCc1ccccc1Cl CHEMBL1318880 Potency 4.0 nM
Cc1cc(-c2cc(C)c(N)c(C)c2)cc(C)c1N CHEMBL1331128 Potency 4.0 nM
COc1cccc(CNC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)c1 CHEMBL1322492 Potency 4.0 nM
Cc1ccc(CNc2c(C)c(C)nc3nncn23)cc1 CHEMBL1517268 Potency 4.0 nM
COc1ccccc1CNC(=O)c1ccc2nc(-c3ccccc3)c(-c3ccccc3)nc2c1 CHEMBL1396870 Potency 4.0 nM
Cc1nnc(N2CCN(c3ccc(Cl)cc3)CC2)c2c1nnn2Cc1ccc(F)cc1 CHEMBL1519203 Potency 4.0 nM
COC(=O)c1cc2sc(Cl)cc2n1Cc1nc(-c2ccc(OC)cc2)oc1C CHEMBL1533333 Potency 4.0 nM
CCOc1ccccc1CNS(=O)(=O)c1cc2c(cc1C)NC(=O)CO2 CHEMBL1524853 Potency 4.0 nM
Cc1ccc2c(c1)CCCN2S(=O)(=O)c1ccc(N2CCCC2=O)cc1 CHEMBL4246320 EC50 4.0 nM
COc1ccc2c(c1)N(C)CCN2S(=O)(=O)c1ccc(N2CCCC2=O)cc1 CHEMBL4238053 EC50 4.0 nM
Cc1ccc(NC(=O)CCS(=O)(=O)c2cc3c4c(c2)CCN4C(=O)CC3)c(C)c1 CHEMBL1555564 Potency 4.5 nM
O=C(NC1CCCC1)c1ccc2c(=O)n(Cc3ccccc3)c(SCc3ccccc3)nc2c1 CHEMBL1531822 Potency 4.5 nM
Cc1ccc(Cl)cc1NC(=O)c1oc2ccc(S(=O)(=O)N3CCCCCC3)cc2c1C CHEMBL1355281 Potency 4.5 nM
Cc1c(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c(=O)n(-c2ccccc2)n1C CHEMBL1338785 Potency 4.5 nM
Cc1ccccc1C(=O)NCCc1nnc(SCC(=O)Nc2nc(-c3ccccc3)cs2)n1C CHEMBL1557722 Potency 4.5 nM
Cc1ccc(-n2c3c(c(=O)[nH]c2=O)C(NC(=O)c2ccccc2C)(C(F)(F)F)C(=O)N3)cc1 CHEMBL1592942 Potency 4.5 nM
Cc1ccc(C)c(NC(=O)CSc2nc(=O)n(CCN(C)C)c3c2CCC3)c1 CHEMBL1573951 Potency 4.5 nM
CC(C)c1ccc(Nc2ncnc3c2c(-c2ccccc2)cn3-c2ccccc2)cc1 CHEMBL1399918 Potency 4.5 nM
Cc1ccc(CCNC(=O)CCn2nc(-c3ccc(C)cc3)ccc2=O)cc1 CHEMBL1604870 Potency 4.5 nM
COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)C(C)C)s2)cc1OC CHEMBL1516341 Potency 4.5 nM
Cc1ccccc1CN1C(=O)c2ccccc2Sc2ccc(C(=O)NC3CCCC3)cc21 CHEMBL1337138 Potency 4.5 nM
CCCCNc1nc2c(-c3cccc(C)c3)nnn2c2ccccc12 CHEMBL1361402 Potency 4.5 nM
Cc1nn(CC(=O)NCc2ccccc2Br)c(=O)c2cc3occc3n12 CHEMBL1320772 Potency 4.5 nM
COc1cccc(-n2c(-c3ccco3)nc3c(cnn3-c3ccccc3C)c2=O)c1 CHEMBL1552385 Potency 4.5 nM
COc1ccc2c(c1)c1c(c(=O)n(Cc3ccccc3)c(=O)n1CC(=O)Nc1ccccc1OC)n2C CHEMBL1555202 Potency 4.5 nM
CCCCn1c(=N)n(CCOc2ccccc2OC)c2ccccc21 CHEMBL1434160 Potency 4.5 nM
CCOC(=O)c1c(NC(=O)c2ccccc2C)sc2c1CCCC2 CHEMBL1316405 Potency 4.5 nM
Cc1ccc(OCCSc2nc(-c3cccs3)nc3cc(=O)[nH]n23)cc1Cl CHEMBL1325385 Potency 4.5 nM
Cc1ccc(O)c(C(=O)c2cnc3c(c2)COc2ccccc2-3)c1 CHEMBL1423211 Potency 4.5 nM
O=[N+]([O-])c1cccc(/C=N\N2CCN(c3ccc(Cl)cc3)CC2)c1 CHEMBL3209388 Potency 4.5 nM
CCCC(=O)N(c1ccc2oc(-c3ccccc3)c(C(=O)OCC)c2c1)S(=O)(=O)c1ccc(C)cc1 CHEMBL1591692 Potency 4.5 nM
Cn1cnc2c(=O)oc3ccc(S(=O)(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3c21 CHEMBL1435850 Potency 4.5 nM
O=c1c2ccccc2nc(/C=C\c2cccc(Br)c2)n1-c1ccc(O)cc1 CHEMBL1555137 Potency 4.5 nM
CC(=O)OCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL1550150 Potency 4.5 nM
COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(C)cc2C)CC1 CHEMBL1315305 Potency 5.0 nM
Cc1c(C(=O)Nc2c(F)cccc2F)sc2ncn(Cc3ccccc3F)c(=O)c12 CHEMBL1336600 Potency 5.0 nM
CC1CCCCN1C(=O)Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O CHEMBL1492555 Potency 5.0 nM
Cc1cc(C)cc(NC(c2nnc(-c3cccc(F)c3)o2)c2ccc(F)cc2Cl)c1 CHEMBL1473567 Potency 5.0 nM
Cc1ccc([S+]([O-])Cc2nc(-c3ccc(C(=O)NCc4cccc(C)c4)cc3)oc2C)cc1 CHEMBL1356727 Potency 5.0 nM
COc1cc(-c2nnc(SCC(=O)Oc3ccccc3)o2)cc(OC)c1OC CHEMBL1512202 Potency 5.0 nM
CC(C)COC(=O)/C(C#N)=C\c1ccc(-c2ccccc2Cl)o1 CHEMBL1434309 Potency 5.0 nM
O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(Cn2c(=O)c3ccccc3n(Cc3ccccc3)c2=O)cc1 CHEMBL1590157 Potency 5.0 nM
CCOc1ccc(CCNC(=O)C2CCCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)C2)cc1 CHEMBL1478739 Potency 5.0 nM
COc1ccc(OCCCn2c(C)nc3cc(C)c(C)cc32)cc1 CHEMBL1480224 Potency 5.0 nM
CC1CCCCN1C(=O)CSc1nnc(-c2ccccc2)[nH]1 CHEMBL1436130 Potency 5.0 nM
Brc1cccc(-c2nnc(CN3CCN(c4ccccn4)CC3)o2)c1 CHEMBL1553967 Potency 5.0 nM
O=C(Nc1cc2c(cc1C(=O)c1ccc(Br)cc1)OCCO2)c1ccc(Cl)cc1 CHEMBL1437410 Potency 5.0 nM
CC(C)CCN1C(=O)c2ccccc2CC1(C)C(=O)NC1CCCCC1 CHEMBL1519556 Potency 5.0 nM
CCOC(=O)c1cccc(NC(=O)c2cc3cc4cc(OC)ccc4nc3s2)c1 CHEMBL1476197 Potency 5.0 nM
COC(=O)c1c(NC(=O)COc2cccc(C(F)(F)F)c2)sc2c1CCCC2 CHEMBL1512493 Potency 5.0 nM
CCc1ccc2occ(CC(=O)Nc3nnc(SC)s3)c2c1 CHEMBL1372100 Potency 5.0 nM
COc1cc2[nH]c(=O)n(-c3ccc(C)cc3)c(=O)c2cc1OC CHEMBL1452460 Potency 5.0 nM
CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 CHEMBL1355113 Potency 5.0 nM
Cc1cccc(N2CCN(C(=O)CCc3c(C)nc4c(c3C)c(=O)n(C)c(=O)n4C)CC2)c1C CHEMBL1448537 Potency 5.0 nM
COC(=O)c1cc2sc(C)cc2n1CC(=O)Nc1cccc(SC)c1 CHEMBL1317466 Potency 5.0 nM
COc1cc(OC)cc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 CHEMBL1316986 Potency 5.0 nM
CCc1ccccc1NC(=O)c1ccc(CN2C(=O)CCn3nc(C)cc32)cc1 CHEMBL1314733 Potency 5.0 nM
COc1cccc(CNC(=O)Cn2cc3c(n2)-c2c(oc(C(=O)N4CCCC4)c2C)CC3)c1OC CHEMBL1332750 Potency 5.0 nM
CCC(C)NC(=O)c1cc(Sc2cccc(Cl)c2)nc2ccccc12 CHEMBL1318673 Potency 5.0 nM
CC1(C)CC(=O)C(=NNc2ccc(Cl)cc2)C(=O)C1 CHEMBL1413259 Potency 5.0 nM
Cc1ccc(C(=O)O)cc1-n1c(C)ccc1-c1ccccc1 CHEMBL1523285 Potency 5.0 nM
Cc1ccc2cc3cc(C(=O)N4CCN(c5cccc(C(F)(F)F)c5)CC4)sc3nc2c1 CHEMBL1591006 Potency 5.0 nM
Cc1cccc(OCC(=O)Nc2cc(-c3ccccc3F)nn2-c2ccccc2)c1 CHEMBL1434674 Potency 5.0 nM
CC(C)c1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 CHEMBL1612783 Potency 5.0 nM
CC(=O)N1CCc2c(sc3c2c(=O)n(Cc2ccccc2)c(=O)n3Cc2cccc(Cl)c2)C1 CHEMBL1558740 Potency 5.0 nM
CCOc1cc(/C=C(\C#N)C(=O)NCC2CCCO2)ccc1O CHEMBL1446544 Potency 5.0 nM
Cc1ccccc1OCC(=O)Nc1nnc(SCc2cc(=O)n3cccc(C)c3n2)s1 CHEMBL1550971 Potency 5.0 nM
Cc1ccc(-n2nc3cc(C)c(NC(=O)c4ccc(-c5ccccc5)o4)cc3n2)cc1 CHEMBL1395604 Potency 5.0 nM
O=C(Cn1c(=O)n(CCc2ccccc2)c(=O)c2cccnc21)Nc1ccc(F)cc1 CHEMBL1445563 Potency 5.0 nM
CCC(=O)N1CCc2cc(S(=O)(=O)NCc3ccc(C)cc3)ccc21 CHEMBL1554560 Potency 5.0 nM
COCCNC(=O)CCCN1C(=O)CCn2nc(-c3cccn3C)cc21 CHEMBL1563545 Potency 5.0 nM
CCOc1cc(C(c2c(C)[nH]n(-c3ccccc3)c2=O)c2c(C)[nH]n(-c3ccccc3)c2=O)ccc1O CHEMBL3144899 Potency 5.0 nM
COc1cc2c(cc1OC)C(c1cc(OC)c(O)c(OC)c1)CC(=O)N2 CHEMBL1442329 Potency 5.0 nM
CCc1ccc(NC(=O)CSc2nc(C)c(C(=O)Nc3ccccc3)c(-c3ccc(OC)c(OC)c3)c2C#N)cc1 CHEMBL1475651 Potency 5.0 nM
Cc1ccccc1OCC(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 CHEMBL1356510 Potency 5.0 nM
Cc1ccccc1C(=O)NC1(C(F)(F)F)C(=O)Nc2c1c(=O)[nH]c(=O)n2CCc1ccccc1 CHEMBL1525387 Potency 5.0 nM
COc1ccc(-c2nn(-c3ccc(F)cc3)c3c2cnc2cc4c(cc23)OCO4)cc1 CHEMBL1411802 Potency 5.0 nM
COCc1cc(C)n(CC(=O)Nc2ccc(NC(C)=O)cc2)c(=O)c1C#N CHEMBL1377437 Potency 5.0 nM
Cc1oc(-c2ccccc2F)nc1CS(=O)(=O)CC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1 CHEMBL1591373 Potency 5.0 nM
CCOCCCN(Cc1ccco1)C(=O)c1cc2c(s1)-c1c(C)cccc1OC2 CHEMBL1454572 Potency 5.0 nM
COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(OC)cc2)CC1 CHEMBL1314985 Potency 5.0 nM
N#C/C(=C\c1ccc(-c2cc(Cl)ccc2Cl)o1)C(=O)Nc1ccccc1C(=O)O CHEMBL1475581 Potency 5.0 nM
CSc1cccc(NC(=O)Cn2ncn3c(cc4ccccc43)c2=O)c1 CHEMBL1396227 Potency 5.0 nM
COc1ccc(N(C(=O)c2cccc(C)c2)S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL1412868 Potency 5.0 nM
CCOC(=O)c1ccccc1NC(=O)CN(c1ccccc1OC)S(=O)(=O)c1ccc(C)cc1 CHEMBL1454661 Potency 5.0 nM
Cc1cccc(NC(=O)Cc2ccc(-n3c(C)nc4cccnc43)cc2)c1C CHEMBL1522004 Potency 5.0 nM
COc1ccc(-c2nc(SCC(=O)NCc3nc4ccccc4n3C)n3[nH]c(=O)cc3n2)cc1 CHEMBL1557997 Potency 5.0 nM
Cc1cccc(CCn2c(=O)c3ccccc3n(CC(=O)Nc3ccccc3F)c2=O)c1 CHEMBL1401025 Potency 5.0 nM
Cc1ccc(NC(=O)CSCc2cnn(-c3ccccc3)c2-n2cccc2)c(C)c1 CHEMBL1571028 Potency 5.0 nM
CCOc1ccc(CNC(=O)c2cccc(NC(=O)N3CCSc4ncccc43)c2)cc1 CHEMBL1358440 Potency 5.0 nM
CCCOC(=O)c1ccc(Nc2c(C(=O)OCC)cnc3c(C)cc(Cl)cc23)cc1 CHEMBL1592573 Potency 5.0 nM
CCN(C(=O)CSc1nc(-c2ccccc2)no1)c1ccccc1 CHEMBL1476326 Potency 5.0 nM
COc1ccc(CC(=O)Nc2sc3c(c2C(=O)Nc2cccc(Cl)c2)CCCCC3)cc1 CHEMBL1376648 Potency 5.0 nM
CCOc1ccc(CCNc2nc3c(-c4ccc(C)cc4)nnn3c3ccccc23)cc1OCC CHEMBL1568967 Potency 5.0 nM
COc1ccc(NC(=O)CC2C(=O)N(c3ccc(C)cc3)C(=O)N2C2CCCCC2)cc1 CHEMBL1324609 Potency 5.0 nM
CN(Cc1ccccc1)C(=O)CCS(=O)(=O)c1cc(Br)cc2c1N(C(=O)C1CC1)CC2 CHEMBL1435316 Potency 5.0 nM
COc1ccc(C(F)(F)F)cc1NC(=O)c1sc2nc(-c3cccs3)ccc2c1N CHEMBL1355993 Potency 5.0 nM
O=C(Nc1nc2c(F)cccc2s1)c1ccc(S(=O)(=O)N2CCCc3ccccc32)cc1 CHEMBL1435793 Potency 5.0 nM
COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2OC)cc1 CHEMBL1398464 Potency 5.0 nM
Cc1ccc(C(=O)N2CCc3cc(CNS(=O)(=O)c4ccc(Cl)s4)ccc32)cc1 CHEMBL1594050 Potency 5.0 nM
COc1cc(OC)cc(C(=O)Nc2cc3c(cc2N2CCCCC2)n(C)c(=O)n3C)c1 CHEMBL1472864 Potency 5.0 nM
COc1ccc(N2CCN(C(=O)c3ccc4c(c3)CCN4S(C)(=O)=O)CC2)cc1 CHEMBL1553084 Potency 5.0 nM
COc1ccc(/C=C(\C#N)c2nc(-c3cc4ccccc4oc3=O)cs2)cc1OC CHEMBL1474075 Potency 5.0 nM
Cc1ccc(-c2nnn(CC(=O)N(c3ccc(F)cc3)C(C(=O)NC(C)(C)C)c3ccco3)n2)o1 CHEMBL1310755 Potency 5.0 nM
CCCn1c(SCc2nc(-c3ccccc3C)no2)nnc1-c1ccc(Cl)cc1 CHEMBL1515466 Potency 5.0 nM
Cc1ccc(CN(Cc2ccco2)C(=O)c2ccccc2Cl)o1 CHEMBL1555741 Potency 5.0 nM
Cc1ccc2oc(-c3cccc(NC(=O)Cc4ccc(Cl)cc4)c3)nc2c1 CHEMBL1512009 Potency 5.0 nM
O=C(NCc1ccccc1Cl)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 CHEMBL1595399 Potency 5.0 nM
N#C/C(=C\c1ccc(Cl)cc1Cl)c1nc(-c2cccc(Cl)c2)cs1 CHEMBL1516328 Potency 5.0 nM
CCc1cccc(C)c1NC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C CHEMBL1591608 Potency 5.0 nM
CC(C)Sc1ncc(Cl)c(C(=O)N(Cc2ccc(N(C)C)cc2)C2CCS(=O)(=O)C2)n1 CHEMBL1607528 Potency 5.0 nM
CCOc1ccc(NC(=O)c2cc3sc(Cl)cc3n2CC)cc1 CHEMBL1397109 Potency 5.0 nM
Cc1cc(C)n(-c2nc3cc(Cl)ccc3nc2N2CCN(c3cccc(C)c3C)CC2)n1 CHEMBL1318500 Potency 5.0 nM
CCC(C)NC(=O)c1cccc(NC(=O)c2nsc3ccccc23)c1 CHEMBL1394547 Potency 5.0 nM
Cc1ccc(S(=O)(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1 CHEMBL1439913 Potency 5.0 nM
COc1ccc(NC(=O)CCN2CCN(CCO)CC2)c(OC)c1 CHEMBL1474849 Potency 5.0 nM
O=C/C(=C\Nc1ccc(Cl)cn1)c1nc2ccccc2o1 CHEMBL1582611 Potency 5.0 nM
CC1CCN(S(=O)(=O)c2ccc3nc(Nc4cccc(F)c4)ccc3c2)CC1 CHEMBL1358237 Potency 5.0 nM
CC(=O)c1cc(-c2ccccc2)n(CCC(=O)Nc2nc3c(C)cccc3s2)c1C CHEMBL1594045 Potency 5.0 nM
COc1ccccc1N1CCN(c2nc3ccccc3n3cnnc23)CC1 CHEMBL1606261 Potency 5.0 nM
COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(F)cc2)CC1 CHEMBL1515740 Potency 5.0 nM
COc1ccccc1N1CCN(S(=O)(=O)c2c(C)sc3ncn(CC(=O)N(C)c4ccc(Cl)cc4)c(=O)c23)CC1 CHEMBL1358088 Potency 5.0 nM
CC(C)CN(CCNC(=O)CCN1N=C(c2ccccc2)CCC1=O)CC(C)C CHEMBL1321311 Potency 5.0 nM
O=C(COc1ccccc1F)Nc1ccc2nc(SCC(=O)N3CCOCC3)sc2c1 CHEMBL1514496 Potency 5.0 nM
Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 CHEMBL1553391 Potency 5.0 nM
Cc1nnc(NCc2ccccc2)c2c1nnn2Cc1ccccc1Cl CHEMBL1396045 Potency 5.0 nM
CCc1ccc(OCC(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)cc1 CHEMBL1530889 Potency 5.0 nM
COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccccc2OC)CC1 CHEMBL1317891 Potency 5.0 nM
CCOc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3cc(C)on3)cc2)cc1 CHEMBL1590786 Potency 5.0 nM
Cc1c(Cl)cccc1NC(=O)CSc1nc(=O)[nH]c2c1CCC2 CHEMBL1524437 Potency 5.0 nM
Cc1ccc(OCCSc2nc3ccccc3n2CCC(=O)O)cc1C CHEMBL1480808 Potency 5.0 nM
CCCN(C(=O)CCNC(=O)Cn1cnc2ccccc2c1=O)c1cccc(C)c1 CHEMBL1401739 Potency 5.0 nM
COc1cccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cc3ccccc3o2)c1 CHEMBL1513379 Potency 5.0 nM
Cc1cc(O)c(C(c2cccc(F)c2)N2CCN(c3ccccc3)CC2)c(=O)n1Cc1ccco1 CHEMBL1394149 Potency 5.0 nM
O=C(NCc1ccc(F)cc1)C(=O)NCC(c1cccs1)S(=O)(=O)c1cccs1 CHEMBL1531075 Potency 5.0 nM
Fc1ccccc1N1CCN(c2nc3ccccc3c3nc(-c4ccccc4)nn23)CC1 CHEMBL1413522 Potency 5.0 nM
CCCOc1ccc(C2CC(=O)Nc3c2c(=O)n(C)c(=O)n3C)cc1OC CHEMBL1591214 Potency 5.0 nM
Cc1ccc(/C=C/c2nc3ccccc3n2S(=O)(=O)c2ccc(Br)cc2)cc1 CHEMBL1439787 Potency 5.0 nM
COc1ccc(F)cc1S(=O)(=O)NCCc1sc2nc(-c3ccc(F)cc3)nn2c1C CHEMBL1455903 Potency 5.0 nM
COc1cccc2c1cc1c(=O)n(CC(=O)NC3CC3)nc(C)n12 CHEMBL1602210 Potency 5.0 nM
Cn1c(=O)c(=O)n(C)c2cc(NS(=O)(=O)c3ccc(Br)cc3)c(Cl)cc21 CHEMBL1435354 Potency 5.0 nM
O=C(CCc1nnc2n(Cc3ccccc3Cl)c(=O)c3ccccc3n12)Nc1ccccc1 CHEMBL1437497 Potency 5.0 nM
Cc1cccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4[nH]c5c(c4c3)CCCCC5)CC2)c1 CHEMBL1605745 Potency 5.0 nM
COc1ccc2c(c1)c1c(c(=O)n(-c3cc(Cl)ccc3C)c(=O)n1CC(=O)N1CCCC1)n2C CHEMBL1551965 Potency 5.0 nM
CCOc1ccc(CCNC(=O)CSc2nnc(-c3ccccc3)[nH]2)cc1OCC CHEMBL1359834 Potency 5.0 nM
Cn1cnnc1Sc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1Cl CHEMBL1343754 Potency 5.0 nM
C=Cc1ccc(Cn2c(C(=O)OC)cc3sc(C)cc32)cc1 CHEMBL1357727 Potency 5.0 nM
COc1ccc(C(=O)N2c3ccccc3C(C)(c3ccc(Cl)cc3)CC2(C)C)cc1 CHEMBL1590707 Potency 5.0 nM
CNc1oc(-c2ccc(COc3ccc(C)cc3)o2)nc1C#N CHEMBL1320967 Potency 5.0 nM
Cc1nc2c(C(=O)NCCc3ccc(Cl)cc3)cnn2c(C)c1Cc1ccc(F)cc1 CHEMBL1596472 Potency 5.0 nM
CCc1ccccc1NC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccc(Br)cc1 CHEMBL1437195 Potency 5.0 nM
CN1C(=O)CC(C(=O)Nc2ccc(C(=O)O)cc2)S/C1=N/c1ccc(Cl)cc1 CHEMBL1354865 Potency 5.0 nM
CCN(CC)CCn1c(-c2ccccc2)cs/c1=N\c1ccccc1 CHEMBL1435075 Potency 5.0 nM
COc1ccc(-c2nc3cc(C(C)C)ccc3o2)cc1NC(=O)COc1ccc(C)cc1C CHEMBL1533759 Potency 5.0 nM
COc1ccc(-c2noc(CSc3nnc(-c4ccncc4)n3-c3cccc(C)c3)n2)cc1OC CHEMBL1574439 Potency 5.0 nM
CCN1CCN(CCCNC(=O)Cn2nc(C)n3c(cc4c(OC)cccc43)c2=O)CC1 CHEMBL1329694 Potency 5.0 nM
CCOc1ccc(Cn2nnc(C(=O)Nc3cccc(SC)c3)c2N)cc1 CHEMBL1529488 Potency 5.0 nM
Cc1cccc(-n2c(/C=C/c3c[nH]c4ccccc34)nc3ccccc3c2=O)c1 CHEMBL1443220 Potency 5.0 nM
CCN(Cc1ccccc1)Cc1c(O)ccc2c(=O)c(-c3ccc(Cl)cc3)coc12 CHEMBL1516300 Potency 5.0 nM
Cc1ccc(C)c(NC(=O)CN(C)S(=O)(=O)c2cccc3cccnc23)c1 CHEMBL1445391 Potency 5.0 nM
Cc1oc2cc3oc(=O)c(CC(=O)NCc4ccccc4)c(C)c3cc2c1C CHEMBL1521105 Potency 5.0 nM
O=C(Cn1cc(SCc2ccc(F)cc2)c2ccccc21)N1CCCC1 CHEMBL1472766 Potency 5.0 nM
CCOc1ccc(C(=O)NCC(c2ccc(Cl)cc2)N2CCCCC2)cc1 CHEMBL1556388 Potency 5.0 nM
Cc1ccc(C)c(N2CCN(C3=C(c4ccccc4)C(=O)c4ccccc43)CC2)c1 CHEMBL1551355 Potency 5.0 nM
CCn1c(C)c(C)c2cc(C(=O)NCc3ccc(OC)cc3OC)ccc21 CHEMBL1553402 Potency 5.0 nM
CCOc1ccc(-c2cc(C(=O)Oc3ccc(C#N)cc3)no2)cc1 CHEMBL1561417 Potency 5.0 nM
CCC1(C)CC(=O)c2c(ccc3oc(C(=O)Nc4ccc(C(C)=O)cc4)c(C)c23)O1 CHEMBL1404648 Potency 5.0 nM
CCc1cccc(C)c1NC(=O)C(CC)n1ncn2c(cc3cc(C)ccc32)c1=O CHEMBL1592971 Potency 5.0 nM
CCCOc1ccc(C(=O)Nc2ccc3oc(-c4ccncc4)nc3c2)cc1 CHEMBL1320283 Potency 5.0 nM
CCCOc1ccc(C2C(=O)N(C3CCCCCC3)CC(=O)N2C(C)C)cc1OC CHEMBL1435498 Potency 5.0 nM
Cc1ccc(C)c(N(C)C(=O)CCNC(=O)Cn2cnc3ccccc3c2=O)c1 CHEMBL1433519 Potency 5.0 nM
CC(NC(=O)Cn1c(=O)oc2cc(S(=O)(=O)NCc3ccccc3)ccc21)c1ccccc1 CHEMBL1590435 Potency 5.0 nM
Cc1cc(=O)oc2cc(OCC(=O)Nc3ccc(O)c(C(=O)O)c3)ccc12 CHEMBL1481529 Potency 5.0 nM
CCCCn1c(-c2ccc(S(=O)(=O)N3CCOCC3)cc2)cs/c1=N\c1ccccc1 CHEMBL1521811 Potency 5.0 nM
CCOC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(Cl)c(C)c1 CHEMBL1513915 Potency 5.0 nM
CC(C)c1ccc(Nc2sc(C(=O)c3ccccc3)c(N)c2S(=O)(=O)c2ccccc2)cc1 CHEMBL1522976 Potency 5.0 nM
CC(=O)c1ccc(NC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 CHEMBL1608466 Potency 5.0 nM
CCCCNC(=O)CCn1c(=O)c2ccccc2n(Cc2cccc(Cl)c2)c1=O CHEMBL1591270 Potency 5.0 nM
CCC(C)OC(=O)/C(C#N)=C\c1ccc(-c2cccc(C(F)(F)F)c2)o1 CHEMBL1595672 Potency 5.0 nM
O=c1[nH]c2ccccc2c(=O)n1-c1ccc(Cl)c(Cl)c1 CHEMBL1575010 Potency 5.0 nM
COC(=O)c1cc2oc(C)cc2n1CC(=O)Nc1ccc(C(C)C)cc1 CHEMBL1316693 Potency 5.0 nM
O=C(CC1N=C2c3ccccc3N=C(SCC(=O)Nc3ccccc3F)N2C1=O)NCc1cccs1 CHEMBL1442433 Potency 5.0 nM
CCc1ccc(NS(=O)(=O)c2ccc3[nH]cc(C(=O)NCCc4cccc(C)c4)c(=O)c3c2)cc1 CHEMBL1397321 Potency 5.0 nM
COc1ccc(NC(=O)C2Cc3ccccc3CN2S(=O)(=O)c2ccccc2)cc1OC CHEMBL1405918 Potency 5.0 nM
COc1cc(OC)c(N(C)C(=O)c2cn(C3CCCC3)c(=O)c3c2c2ccccc2n3C)cc1Cl CHEMBL578523 Potency 5.0 nM
COC(=O)c1c(C)oc2ccc(N(C(=O)Oc3ccccc3)S(=O)(=O)c3ccc(C(C)(C)C)cc3)cc12 CHEMBL1552006 Potency 5.0 nM
O=C(c1ccccc1)N1CCc2cc(CNS(=O)(=O)c3ccccc3Cl)ccc21 CHEMBL1404117 Potency 5.0 nM
Cc1cc(C)c(S(=O)(=O)NCCc2cc3ccc(C)cc3[nH]c2=O)c(C)c1 CHEMBL1571466 Potency 5.0 nM
Cc1ccc(-c2nc(-c3cc4cccc(OCc5cccc(F)c5)c4oc3=O)no2)cc1 CHEMBL1531937 Potency 5.0 nM
COc1ccc(Cl)cc1NC(=O)CSc1nc(=O)n(Cc2ccco2)c2c1CCC2 CHEMBL1355283 Potency 5.0 nM
CCOc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3cc(OC)c(OC)cc32)cc1 CHEMBL1590529 Potency 5.0 nM
Cc1ccc2nc(Nc3ccc(Br)cc3)nc(-c3ccccc3)c2c1 CHEMBL1516181 Potency 5.0 nM
Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O CHEMBL1552691 Potency 5.0 nM
COc1cccc(NC(=O)CSc2nc3ccc(NC(=O)c4cccs4)cc3s2)c1 CHEMBL1551167 Potency 5.0 nM
COc1ccc(C(=O)c2oc3ccccc3c2NC(=O)COc2ccccc2)cc1 CHEMBL1512272 Potency 5.0 nM
Cc1cc(Sc2ccc(Cl)cc2)nc2ccccc12 CHEMBL1513868 Potency 5.0 nM
Cc1ccc2nc(COc3ccccc3NC(=O)C(C)(C)C)cc(=O)n2c1 CHEMBL1406561 Potency 5.0 nM
Cc1cccn2c(=O)cc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)nc12 CHEMBL1611154 Potency 5.0 nM
CCOC(=O)N1CCc2c(sc(NCc3cc(OC)c(OC)cc3OC)c2C(=O)Nc2ccc(OCC)cc2)C1 CHEMBL1562701 Potency 5.0 nM
O=C(c1ccc(CSc2nc3ccncc3n2Cc2ccccc2)cc1)N1CCCCCC1 CHEMBL1358415 Potency 5.0 nM
Cc1ccc(C)c(N2CCN(c3nc4c(S(=O)(=O)c5ccccc5)nnn4c4ccc(Cl)cc34)CC2)c1 CHEMBL1080147 Potency 5.0 nM
Cn1c2c(c(=O)n(C)c1=O)C(c1ccccc1[N+](=O)[O-])CC(=O)N2 CHEMBL1535993 Potency 5.0 nM
Cc1ccc(NC(=O)c2ccc(C)c(S(=O)(=O)N3CCCCCC3)c2)cc1 CHEMBL1528506 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccc(F)cc2)n(CCC(=O)NC2CCC(C)CC2)c1C CHEMBL1496745 Potency 5.0 nM
CCCCN(CC)CCNC(=O)C1CCCN(S(=O)(=O)c2cccc3nsnc23)C1 CHEMBL1506293 Potency 5.0 nM
Cc1ccc(CCNC(=O)c2ccc(CSc3nc4ccncc4n3Cc3ccc(F)cc3)cc2)cc1 CHEMBL1324120 Potency 5.0 nM
O=C(Cc1ccc(NC(=O)N2CCCCc3ccccc32)cc1)NCc1ccccc1 CHEMBL1434562 Potency 5.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(CN1CCN(c3ccc(F)cc3)CC1)n2CCN1CCOCC1 CHEMBL1532222 Potency 5.0 nM
Cn1c(=O)c2nc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)n(C)c2n(C)c1=O CHEMBL1450532 Potency 5.0 nM
Cc1nc2nc(SCC(=O)Nc3cccc(Cl)c3)nn2c(C)c1Cc1ccccc1 CHEMBL1606540 Potency 5.0 nM
CC(=O)Nc1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 CHEMBL1611268 Potency 5.0 nM
CCC(CC)C(=O)Nc1nnc(S(=O)(=O)N2CCCCCC2)s1 CHEMBL1531367 Potency 5.0 nM
O=C(Nc1cc(Cl)cc(Cl)c1)c1cc(S(=O)(=O)N2CCc3ccccc3C2)ccc1F CHEMBL1485841 Potency 5.0 nM
COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3cc(C(C)C)ccc3n2)cc1 CHEMBL1564170 Potency 5.0 nM
O=C(CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1)NCCc1ccccc1 CHEMBL1356552 Potency 5.0 nM
CCOc1ccc(N(CC(=O)NCc2cccc(OC)c2)S(=O)(=O)c2c(C)noc2C)cc1 CHEMBL1598227 Potency 5.0 nM
CC(=O)N1CCN(C(=O)C(=O)Nc2c3c(nn2-c2ccc(Cl)cc2)CSC3)CC1 CHEMBL1607094 Potency 5.0 nM
CC(C)CCNc1ncnc2c1cnn2-c1cccc(Cl)c1 CHEMBL1568662 Potency 5.0 nM
Cc1ccc2c(c1)CC(C)N2S(=O)(=O)c1nnc(NC(=O)c2ccccc2F)s1 CHEMBL1440132 Potency 5.0 nM
Cc1c(C(=O)NCc2ccc(Cl)cc2)sc2nc3n(c(=O)c12)CCCC3 CHEMBL1395688 Potency 5.0 nM
COc1ccc2nc(N3CCN(C(=O)c4ccco4)CC3)sc2c1 CHEMBL1474862 Potency 5.0 nM
CCc1ccc(NC(=O)Cn2ncn3c(cc4ccccc43)c2=O)cc1 CHEMBL1609165 Potency 5.0 nM
Cc1ccc(NC(=O)Cn2c(=O)oc3cc(S(=O)(=O)N4CCCCCC4)ccc32)cc1Cl CHEMBL1335708 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccccc2)n(CCCC(=O)Nc2cccc(Cl)c2C)c1C CHEMBL1571810 Potency 5.0 nM
COc1ccccc1CN1CC(C(=O)NCC2CCCO2)CC1=O CHEMBL1305583 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccc(C)cc2)n(CCC(=O)NCc2ccccc2)c1C CHEMBL1451322 Potency 5.0 nM
Cc1cccn2c(=O)c(C(=O)N3CCN(c4ccccc4)CC3)cnc12 CHEMBL1412694 Potency 5.0 nM
Nc1nnc(SCCCC(=O)c2ccc(Br)cc2)s1 CHEMBL1404519 Potency 5.0 nM
O=C(CCSCc1cccc(Cl)c1)N1CCN(c2ccc(Cl)cc2)CC1 CHEMBL1368492 Potency 5.0 nM
Cc1ccc(NC(=O)CN2C(=O)COc3ccc(S(=O)(=O)N4CCCCCC4)cc32)cc1C CHEMBL1474897 Potency 5.0 nM
CSc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)c1 CHEMBL1551326 Potency 5.0 nM
O=C(NCc1ccc(Cl)cc1)c1ccc(CSCc2cccc(Cl)c2)o1 CHEMBL1364048 Potency 5.0 nM
Cc1ccccc1NC(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1F CHEMBL1317212 Potency 5.0 nM
Cc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1CCc1c[nH]c2ccccc12 CHEMBL1333632 Potency 5.0 nM
COc1ccc(CCNc2ncnc3c2cnn3-c2ccc(C)cc2)cc1 CHEMBL1534449 Potency 5.0 nM
Cc1ccc(C(=O)NCC(c2cccs2)S(=O)(=O)c2cccs2)cc1C CHEMBL1455760 Potency 5.0 nM
CCCCc1ccc(NC(=O)c2ccc3c(c2)CCN3S(=O)(=O)c2ccccc2)cc1 CHEMBL1357890 Potency 5.0 nM
CCN(CC)c1ccc(NC(=O)C2COc3ccc(OC)cc3C2)c(C)c1 CHEMBL1365046 Potency 5.0 nM
COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cccc(F)c2)c(OC)c1 CHEMBL1435797 Potency 5.0 nM
O=C(c1ccco1)N1CCN(c2nc3ccccc3c(=O)n2-c2ccccc2)CC1 CHEMBL1386737 Potency 5.0 nM
CC(=O)Nc1cc(C(=O)NCc2ccc(C)cc2)ccc1Sc1ccc(C)cc1 CHEMBL1474273 Potency 5.0 nM
CCCS(=O)(=O)NCCc1sc2nc(-c3ccc(F)cc3)nn2c1C CHEMBL1476299 Potency 5.0 nM
Cc1cc(C)c(NC(=O)CCS(=O)(=O)c2cc3c(cc2Cl)NC(=O)CO3)c(C)c1 CHEMBL1516450 Potency 5.0 nM
O=C(NCCCN1CCOCC1)c1cc2c(O)nc3ccccc3c2s1 CHEMBL1565727 Potency 5.0 nM
Cc1cc(C)c(NS(=O)(=O)c2ccc(-c3coc(C)n3)cc2)c(C)c1 CHEMBL1531077 Potency 5.0 nM
CCOC(=O)c1ccc(CN(Cc2ccc(C)cc2)S(=O)(=O)c2ccc(NC(C)=O)cc2)cc1 CHEMBL1317215 Potency 5.0 nM
CCC1CCCCN1S(=O)(=O)c1cc(C(=O)Nc2ccc(C)c(F)c2)ccc1F CHEMBL1605337 Potency 5.0 nM
Cc1ccc(-n2nnc(C(=O)Nc3cc(F)ccc3F)c2C)cc1F CHEMBL1456423 Potency 5.0 nM
COc1cc(/C=N/n2cnc3scc(-c4cccs4)c3c2=O)cc(OC)c1OC CHEMBL1995040 Potency 5.0 nM
CCC(=O)Nc1cccc(-c2cn3c(C)csc3n2)c1 CHEMBL1354729 Potency 5.0 nM
O=c1cc(-c2ccccc2)oc2ccccc12 CHEMBL275638 Potency 5.0 nM
CCCCOc1ccc(C(=O)NCCc2sc(-c3ccc(OC)c(OC)c3)nc2C)cc1 CHEMBL1592681 Potency 5.0 nM
COc1ccc(C)cc1NC(=O)c1cc2c(s1)-c1ccccc1SC2 CHEMBL1315300 Potency 5.0 nM
O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 CHEMBL1398005 Potency 5.0 nM
CCOP(=S)(OCC)Oc1cc(C)nc(C(C)C)n1 CHEMBL388560 Potency 5.0 nM
CCCCN(CC)C(=O)CCCn1c(=O)c2cccn2c2ccccc21 CHEMBL1395211 Potency 5.0 nM
COc1cc(OC)c(OC)cc1/C=C/c1nc2cc3ccccc3cc2c(=O)n1-c1ccccc1Br CHEMBL1456673 Potency 5.0 nM
Cc1cccc(N2CCN(S(=O)(=O)c3cc(C(=O)Nc4ccccc4Cl)ccc3F)CC2)c1C CHEMBL1408787 Potency 5.0 nM
Cc1ccccc1NC(=O)CSc1nc2ccc(NC(=O)c3cccs3)cc2s1 CHEMBL1473047 Potency 5.0 nM
CCCS(=O)(=O)N1CCC(C(=O)NCCCN(CC)c2cccc(C)c2)CC1 CHEMBL1576907 Potency 5.0 nM
Cc1ccc(NC(=O)Nc2cccs2)c(C)c1 CHEMBL1316532 Potency 5.0 nM
Cc1cc(C)nc(N(C#N)CC(=O)N2CCC(C(N)=O)CC2)n1 CHEMBL1299689 Potency 5.0 nM
Cn1c(C(=O)NCc2ccccc2Cl)cc2sc(Cl)cc21 CHEMBL1356683 Potency 5.0 nM
COc1ccc(NC(=O)CSc2nc(-c3ccccc3)cc(-c3cc(OC)c(OC)c(OC)c3)c2C#N)c(OC)c1 CHEMBL1354707 Potency 5.0 nM
Cc1nn(C(C)C(=O)Nc2cccc(F)c2)c(=O)c2c1sc1ccccc12 CHEMBL1514543 Potency 5.0 nM
COc1ccccc1NC(=O)CN(C)S(=O)(=O)c1cccc2cccnc12 CHEMBL1384437 Potency 5.0 nM
C=Cc1cccc(C)c1 CHEMBL1381662 Potency 5.0 nM
CCCCOc1ccc(CNC(=O)c2ccc(NC(=O)N3CCCCc4ccccc43)cc2)cc1 CHEMBL1399330 Potency 5.0 nM
CCCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)N3CCCC3)c2=O)CC1 CHEMBL1433994 Potency 5.0 nM
CCc1ccc(Sc2cc(C(=O)O)c3ccccc3n2)cc1 CHEMBL1489124 Potency 5.0 nM
CCOc1ccc(NC(=O)c2cc(S(=O)(=O)NC3CCCC3)ccc2F)cc1 CHEMBL1513916 Potency 5.0 nM
Cc1ccc(Cl)cc1NC(=O)CN1C(=O)COc2ccc(S(=O)(=O)N3CCCCCC3)cc21 CHEMBL1563138 Potency 5.0 nM
COc1cc(OC)c(NC2(c3ccccc3)C(=O)c3ccccc3C2=O)cc1Cl CHEMBL1366682 Potency 5.0 nM
C=CC(=C)C CHEMBL1566132 Potency 5.0 nM
C/C=C\c1ccc(OC)cc1 CHEMBL1468832 Potency 5.0 nM
COc1ccccc1N1CCN(C(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)CC1 CHEMBL1512508 Potency 5.0 nM
COc1cc(C2C(=O)N(C3CCCCC3)CC(=O)N2C2CCCC2)ccc1OC(C)C CHEMBL1415335 Potency 5.0 nM
O=c1c(N2CCN(c3ccc(F)cc3)CC2)csc2ccc(F)cc12 CHEMBL1406603 Potency 5.0 nM
CCc1ccccc1NC(=O)CN(c1ccccc1)S(=O)(=O)c1ccsc1C(=O)OC CHEMBL1398232 Potency 5.0 nM
COc1ccc(NC(=O)CSc2nnc3c(C)cc4ccccc4n23)cc1 CHEMBL1530679 Potency 5.0 nM
CCOc1ccccc1CN1C(=O)NC(C)(c2ccccc2)C1=O CHEMBL1461288 Potency 5.0 nM
O=c1cc(N2CCC(Cc3ccccc3)CC2)[nH]c(=O)n1C1CCCCC1 CHEMBL1548380 Potency 5.0 nM
COc1cccc(C(=O)NCC(c2ccc(N(C)C)cc2)N2CCCC2)c1OC CHEMBL1434142 Potency 5.0 nM
Cc1ccc(CCNC(=O)Cn2c(-c3cccs3)cc3cc(F)ccc32)cc1 CHEMBL1357505 Potency 5.0 nM
Cc1ccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NC4CCCC4)cc32)cc1 CHEMBL1481729 Potency 5.0 nM
Cc1ccc2c(=O)cc(C(=O)Nc3c(C)cccc3C)oc2c1 CHEMBL1397326 Potency 5.0 nM
CCn1cc(C(=O)NCCCN(CC(C)C)CC(C)C)c(=O)c2cc(S(=O)(=O)N(C)C3CCCCC3)ccc21 CHEMBL1327180 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccc(C)cc2)n(CC(=O)Nc2cccc(C(C)=O)c2)c1C CHEMBL1512004 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccccc2)n(CC(=O)NCc2ccccc2OC)c1C CHEMBL1519230 Potency 5.0 nM
O=C(NCc1ccc(F)cc1)c1ccc(CS(=O)(=O)Cc2ccccc2F)o1 CHEMBL1407420 Potency 5.0 nM
O=C(Nc1ccc2c(c1)OCO2)C1CCN(Cc2cnn(-c3ccccc3)c2-n2cccc2)CC1 CHEMBL1413739 Potency 5.0 nM
Cc1ccc(CNC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 CHEMBL1320182 Potency 5.0 nM
CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(CC)C2 CHEMBL1316864 Potency 5.0 nM
COc1ccc(CCNC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1OC CHEMBL1314804 Potency 5.0 nM
CCn1c(=O)n(CC)c2cc(N3CCCCC3)c(NC(=O)Nc3ccccc3C(F)(F)F)cc21 CHEMBL1356968 Potency 5.0 nM
COC(=O)c1sc2ccccc2c1S(=O)(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 CHEMBL1513424 Potency 5.0 nM
CCOC(=O)c1cc(-c2ccc(C)cc2)n(CC(=O)Nc2ccccc2F)c1C CHEMBL1397549 Potency 5.0 nM
O=C(CN1C=NS(=O)(=O)c2ccccc21)Nc1ccc(F)cc1 CHEMBL1415698 Potency 5.0 nM
CCN(CC)C(=O)C1CCCN(c2ncnc3c2c(-c2ccccc2)cn3-c2cccc(C)c2)C1 CHEMBL1327499 Potency 5.0 nM
O=C(O)c1ccc(C(=O)O)cc1 CHEMBL1374420 Potency 5.0 nM
CCCN1Cc2cccc(C(=O)Nc3ccc(OC)c(OC)c3)c2C1=O CHEMBL1462542 Potency 5.0 nM
CCOP(=O)(Cl)Cl CHEMBL1334159 Potency 5.0 nM
C=C(C)c1cccc(C(C)(C)NC(=O)Nc2ccc(C)cn2)c1 CHEMBL1549783 Potency 5.0 nM
COc1ccc(NC(=O)c2c(NCc3cccc(F)c3)sc3c2CCC3)c(OC)c1 CHEMBL1603375 Potency 5.0 nM
COc1ccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c2cccc3nonc23)cc1OC CHEMBL1322265 Potency 5.6 nM
C1CCN(Cc2nnnn2C2CCCC2)CC1 CHEMBL1503989 Potency 5.6 nM
CCC(=O)N1CCc2cc(S(=O)(=O)N3CCN(c4ccccc4F)CC3)ccc21 CHEMBL1606953 Potency 5.6 nM
CCC(=O)N1CCc2cc(S(=O)(=O)NC(C(=O)Nc3cc(OC)cc(OC)c3)C(C)C)ccc21 CHEMBL1552836 Potency 5.6 nM
O=C(Nc1cc(F)ccc1F)c1cnn2c(C(F)F)cc(-c3ccccc3)nc12 CHEMBL1319250 Potency 5.6 nM
COc1ccc(S(=O)(=O)NCc2ccc3c(c2)CCN3C(=O)c2ccc(C)cc2)cc1Cl CHEMBL1434672 Potency 5.6 nM
CC(C)c1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1 CHEMBL1320105 Potency 5.6 nM
Cc1cccc(CCNC(=O)C2CCC(CNS(=O)(=O)c3c(C)cc(C)cc3C)CC2)c1 CHEMBL1377735 Potency 6.3 nM
CN(C(=O)c1cc2c(s1)-c1ccc(Cl)cc1SC2)c1cccc(C(F)(F)F)c1 CHEMBL1441621 Potency 6.3 nM
COc1ccc(OC)c(NC(=O)Cc2c(C)n(C(=O)c3ccc(Cl)cc3)c3ccc(OC)cc23)c1 CHEMBL1395589 Potency 6.3 nM
CCC(C(=O)Nc1cc(C(F)(F)F)ccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O CHEMBL1324580 Potency 6.3 nM
CCCCOc1cccc(C(=O)Nc2cccc(-c3nc4ncccc4o3)c2C)c1 CHEMBL1401765 Potency 6.3 nM
CCCOc1ccc(-c2nc3ccc(Br)cc3c(=O)o2)cc1 CHEMBL1333682 Potency 6.3 nM
COCc1cc(C)nc2c1C(=O)NC(c1ccc(C)cc1)N2Cc1ccccc1 CHEMBL1356130 Potency 6.3 nM
CCOc1ccc(C(=O)Nc2nnc(SCc3cc(=O)n4ccccc4n3)s2)cc1 CHEMBL1551529 Potency 6.3 nM
O=C(Nc1ccc(C(=O)N2CCN(c3ccccc3)CC2)cc1)c1nsc2ccccc12 CHEMBL1590260 Potency 6.3 nM
CCSc1nnnn1-c1cccc(C(=O)O)c1 CHEMBL1606894 Potency 6.3 nM
O=C(/C=C/c1ccco1)Nc1ccc(F)cc1 CHEMBL1472780 Potency 6.3 nM
Cc1cc(O)c(C(c2ccccc2Cl)N2CCN(c3ccccc3)CC2)c(=O)n1Cc1ccco1 CHEMBL1435205 Potency 6.3 nM
CN1CCc2c(sc3c2C(=O)NC(c2ccc(OC(=O)c4ccc(Cl)cc4)cc2)N3)C1 CHEMBL1564650 Potency 6.3 nM
Cc1cc(NC(=O)c2ccccc2Cl)ccc1NC(=O)c1ccccc1 CHEMBL1317444 Potency 6.3 nM
Cc1cccc(NC(=O)CN2C(=O)CC(c3ccccc3)Sc3ccccc32)c1 CHEMBL1357202 Potency 6.3 nM
CCC(CC)C(=O)Nc1cc(-c2cccc(C)c2)nn1-c1ccccc1 CHEMBL1331325 Potency 6.3 nM
Cc1ccc(Cl)cc1NC(=O)c1ccc(-c2nc(CSc3ccccc3)c(C)o2)cc1 CHEMBL1395945 Potency 6.3 nM
Cc1cccc(Nc2ncnc3c2cnn3C)c1C CHEMBL1368445 Potency 6.3 nM
COc1ccc(SCc2cc(=O)c3cc(Cl)ccc3[nH]2)cc1 CHEMBL1571714 Potency 6.3 nM
CCN1CCN(C(c2ccccc2F)c2c(O)cc(C)n(CCOC)c2=O)CC1 CHEMBL1395525 Potency 6.3 nM
CCc1nnc(SCC(=O)Nc2ccc(OC)c(OC)c2)c2cc3occc3n12 CHEMBL1554189 Potency 6.3 nM
COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(C(=O)OC)ccc21 CHEMBL1516075 Potency 6.3 nM
O=C(COCc1cc(-c2ccc(F)cc2)on1)Nc1cc(F)ccc1F CHEMBL1434024 Potency 6.3 nM
CCOC(=O)c1cc(-c2ccccc2)n(CC(=O)N(C)c2ccc(OC)cc2)c1C CHEMBL1398435 Potency 6.3 nM
Nc1nc(Nc2cccc(Cl)c2)sc1C(=O)c1ccc(F)cc1 CHEMBL1437953 Potency 6.3 nM
COc1cccc(C2=CC(c3cc(Br)ccc3F)n3nnnc3N2)c1 CHEMBL1444601 Potency 6.3 nM
C=Cc1ccc(Cn2c(C)c(CNCc3cccc(Br)c3)c(C(=O)O)c2C)cc1 CHEMBL1397511 Potency 6.3 nM
Cc1ccc(N2CCN(S(=O)(=O)c3cccc4ccccc34)CC2)cc1Cl CHEMBL1315569 Potency 6.3 nM
c1ccc2cc3c(cc2c1)-c1cccc2cccc-3c12 CHEMBL1441574 Potency 6.3 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H](C(=O)O)[C@@H](OC(=O)/C=C/c1ccc(O)c(O)c1)C(=O)O CHEMBL282731 Potency 6.3 nM
Cc1ccc2nc(NC(=O)CSc3nccn3Cc3ccc(Cl)cc3)sc2c1 CHEMBL1443087 Potency 6.3 nM
Cc1ccc(-c2nnn3c2nc(NCCc2ccccc2)c2ccccc23)cc1 CHEMBL1357624 Potency 6.3 nM
CC(=O)N1CCCc2cc(S(=O)(=O)N3CCN(c4ccccn4)CC3)ccc21 CHEMBL1331053 Potency 6.3 nM
O=C(Nc1nnc(S(=O)(=O)Nc2ccccc2)s1)C1CCCCC1 CHEMBL1603181 Potency 6.3 nM
CCc1ccccc1 CHEMBL371561 Potency 6.3 nM
O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1cccc(Cl)c1 CHEMBL1395287 Potency 6.3 nM
CCCS(=O)(=O)NCCc1csc2nc(-c3ccc(C)cc3)nn12 CHEMBL1592700 Potency 6.3 nM
Cc1cnc2c(c1SCC(=O)Nc1ccc(F)cc1F)c(=O)n(C)c(=O)n2C CHEMBL1551403 Potency 6.3 nM
COc1ccc(/C=C/C(=O)Nc2nc(-c3cccs3)ns2)cc1 CHEMBL1555511 Potency 6.3 nM
COc1cc(NC(=O)c2cc(S(=O)(=O)N3CCC(C)CC3)cn2C)cc(OC)c1OC CHEMBL1315064 Potency 6.3 nM
Cc1cc(C(=O)NCc2ccc(Cl)cc2)c2c(C)nn(-c3ccccc3)c2n1 CHEMBL1592098 Potency 6.3 nM
Cc1ccc(CS(=O)(=O)CCC(=O)NCC2CCCO2)cc1 CHEMBL1543972 Potency 6.3 nM
CN(C(=O)CSc1nc(O)c2c(n1)CCCC2)C1CCCCC1 CHEMBL1582714 Potency 6.3 nM
COc1ccc(-c2nc3scc(CCNS(=O)(=O)c4ccc5c(c4)OCCO5)n3n2)cc1 CHEMBL1317251 Potency 6.3 nM
CCOc1ccc(NC(=O)CN2CCN(C3CCCCC3)C(=O)C2=O)cc1 CHEMBL1395831 Potency 6.3 nM
CCOC(=O)N1CCC(NC(=O)CCc2nc(-c3ccccc3F)no2)CC1 CHEMBL1398842 Potency 6.3 nM
COc1cc2nc(S)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC CHEMBL1561495 Potency 6.3 nM
CCn1c(SCC(=O)Nc2nc3ccccc3s2)nc2c(c1=O)SC(C)C2 CHEMBL1444402 Potency 6.3 nM
CC1(C)CC(=O)C2=C(C1)NC(=O)CC2c1cc2c(cc1Br)OCO2 CHEMBL1507341 Potency 6.3 nM
COc1cc2nc(N3CCN(C(=O)[C@H]4CCCO4)CC3)nc(N)c2cc1OC CHEMBL1481149 Potency 6.3 nM
COCCCNC(=O)CN1C(=O)COc2ccc(S(=O)(=O)N3CCCCCC3)cc21 CHEMBL1491008 Potency 6.3 nM
CC(C)CCN1C(=O)c2ccc(C(=O)OCn3nnc4ccccc4c3=O)cc2C1=O CHEMBL1529421 Potency 6.3 nM
Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccccc2C#N)n1 CHEMBL1613541 Potency 6.3 nM
COCCCNC(=O)c1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2 CHEMBL1591015 Potency 6.3 nM
Cc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3c(C)n[nH]c3C)C2)c(C)c1 CHEMBL1598204 Potency 6.3 nM
COc1ccc(CNC(=O)c2ccc(CS(=O)(=O)c3ccccc3OC)o2)cc1 CHEMBL1321501 Potency 6.3 nM
O=C(O)C(Cl)(Cl)Cl CHEMBL14053 Potency 6.3 nM
COC(=O)C1C2c3ccccc3OC1(C)N=c1s/c(=C/c3cnn(C)c3)c(=O)n12 CHEMBL3209194 Potency 6.3 nM
COc1ccc(-n2c(/C=C/c3cccc4ccccc34)nc3ccccc3c2=O)cc1Cl CHEMBL1399555 Potency 6.3 nM
COc1ccc(C2CC(=O)N(Cc3cccc(C)c3)c3c2c(C)nn3-c2nc(C)cc(C)n2)c(OC)c1 CHEMBL1435940 Potency 6.3 nM
CCC(=O)N1CCc2cc(S(=O)(=O)NCCC(=O)N3CC=C(c4ccccc4)CC3)ccc21 CHEMBL1558496 Potency 6.3 nM
CCOCCCNC(=O)C1CCC(CNS(=O)(=O)c2ccc(NC(C)=O)cc2)CC1 CHEMBL1413837 Potency 6.3 nM
CCOC(=O)CSc1nc2c(c(=O)n1-c1ccc(OCC)cc1)SCC2 CHEMBL1352323 Potency 6.3 nM
CCC(Sc1nc2nnc(C)c-2c(N)n1-c1ccc(C)c(Cl)c1)C(=O)N1CCOCC1 CHEMBL1549387 Potency 6.3 nM
CCOc1ccc(CCNC(=O)C(CC)n2nc(C)n3c(cc4sccc43)c2=O)cc1OCC CHEMBL1374191 Potency 6.3 nM
O=S(=O)([O-])[O-] CHEMBL1549844 Potency 6.3 nM
COc1ccc(NC(=O)Cn2c(-c3ccc(F)cc3)cc(C(C)=O)c2C)c(OC)c1 CHEMBL1512599 Potency 7.1 nM
Cc1cc(SCC(=O)c2ccccc2)n2nc(C)nc2n1 CHEMBL1518248 Potency 7.1 nM
CCC(C)NC(=O)CCC(=O)NNc1nc2ccccc2c2nc(C)nn12 CHEMBL1351149 Potency 7.1 nM
COc1ccc(NC(=O)CSc2nc(-c3ccc(OC)cc3)cc(=O)[nH]2)cc1 CHEMBL1590606 Potency 7.1 nM
COc1ccc(C2NC(=O)NC(C)=C2C(C)=O)cc1 CHEMBL1369396 Potency 7.1 nM
COc1cccc(-c2nc(S(=O)(=O)c3ccccc3)c(NCc3ccccc3)o2)c1 CHEMBL1595834 Potency 7.1 nM
COc1ccc(-n2c(=O)c3c(c4cc(OC)ccc4n3C)n(Cc3cccc(C)c3)c2=O)cc1 CHEMBL1555381 Potency 7.1 nM
O=C(C1CCC(CNS(=O)(=O)c2ccc(Br)s2)CC1)N1CCN(c2ccccc2Cl)CC1 CHEMBL1354613 Potency 7.1 nM
Cn1c(Cn2c(=O)sc3ccccc32)nnc1SCC(=O)Nc1ccccc1 CHEMBL1433283 Potency 7.1 nM
CCOc1ccccc1N(CC(=O)N1CCc2ccccc2C1)S(=O)(=O)c1ccccc1 CHEMBL1358113 Potency 7.1 nM
COc1ccc(C(=O)CCC(=O)Nc2cccc(C(C)=O)c2)cc1 CHEMBL1369934 Potency 7.1 nM
CC1CCCCN1C(=O)c1cc(-c2ccc(Br)cc2)on1 CHEMBL1315472 Potency 7.1 nM
COc1ccccc1N1CCN(C(=O)CCc2c(C)nn(-c3ccc(N4CCCC4)nn3)c2C)CC1 CHEMBL1476800 Potency 7.9 nM
COc1cc(NC(=O)C(CCSC)NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)cc(OC)c1 CHEMBL1474385 Potency 7.9 nM
O=[N+]([O-])c1cc(-c2nc(-c3ccco3)no2)ccc1NCc1ccccc1 CHEMBL1556802 Potency 7.9 nM
CCCOc1ccc(C2c3c(oc4ccccc4c3=O)C(=O)N2c2ccc(C)cn2)cc1OCC CHEMBL1315809 Potency 7.9 nM
Cc1ccc(CCNC(=O)c2ccc(CNS(=O)(=O)c3ccc(C)cc3)cc2)cc1 CHEMBL1534805 Potency 7.9 nM
Cn1nnnc1SCCCNCc1ccc(Cl)cc1 CHEMBL1553017 Potency 7.9 nM
CCCc1ccc(OCC(=O)Nc2sc3c(c2C(=O)OC)CCCCC3)cc1 CHEMBL1567564 Potency 7.9 nM
COc1ccccc1-c1c(C)nn2c(N3CCN(c4ccc(Cl)cc4)CC3)cc(C)nc12 CHEMBL1590997 Potency 7.9 nM
COc1cccc(CSc2nc3ccncc3n2CC(=O)Nc2ccc(OC)c(OC)c2OC)c1 CHEMBL1395440 Potency 7.9 nM
CC(=O)N1c2ccccc2C(=O)C1N1CCN(c2ccccc2F)CC1 CHEMBL1512341 Potency 7.9 nM
COCCCNC(=O)CCCN1C(=O)CCn2nc(-c3cccn3C)cc21 CHEMBL1530798 Potency 7.9 nM
COc1ccc(C(=O)CCC(=O)Nc2ccc(F)cc2F)cc1 CHEMBL1594839 Potency 7.9 nM
Cc1ccc(C(=O)NCc2ccc3c(c2)CCN3C(=O)c2ccc(C)cc2)cc1 CHEMBL1514240 Potency 7.9 nM
CCOc1ccc(C(=O)Nc2cc(-c3nc4ccccc4o3)ccc2C)cc1Cl CHEMBL1394578 Potency 7.9 nM
Cc1nnc(NC(=O)CSc2nnc(Cc3cccn3C)n2-c2cccc(C)c2C)s1 CHEMBL1487596 Potency 7.9 nM
CCCCOc1ccc(C(=O)Nc2onc3c2CCCC3)cc1 CHEMBL1594046 Potency 7.9 nM
O=C(NCc1ccccc1Cl)c1ccc2c(c1)ncn2-c1cccc(F)c1 CHEMBL1357141 Potency 7.9 nM
CCC1=Nc2cc(C(=O)NCCc3ccc(OC)c(OC)c3)ccc2Sc2ccccc21 CHEMBL1551190 Potency 7.9 nM
CC1=C(C(=O)Nc2ccc(C)cc2C)C(c2cccn2C)n2ncnc2N1 CHEMBL1396039 Potency 7.9 nM
COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)NCc2ccccc2)cc1 CHEMBL1592895 Potency 7.9 nM
COc1ccc(N(C(=O)COc2ccccc2OC)S(=O)(=O)c2ccc(Cl)cc2)cc1 CHEMBL1535323 Potency 7.9 nM
CC(=O)Nc1ccc(S(=O)(=O)NCc2ccc(C(=O)NCc3ccc(Cl)cc3)cc2)cc1 CHEMBL1330964 Potency 7.9 nM
Cc1ccc(N(Cc2cccs2)C(=O)COc2ccccc2[N+](=O)[O-])cc1 CHEMBL1551568 Potency 7.9 nM
COc1ccc(N(CC(=O)N2CCCCC2)S(=O)(=O)c2ccc(OC)c(OC)c2)cc1 CHEMBL1354878 Potency 7.9 nM
COc1cc2ccccc2cc1C(=O)Nc1cccc(-c2nc3cc(C)c(C)cc3o2)c1 CHEMBL1456954 Potency 7.9 nM
Cc1cccc(NC(=O)c2ccc3snnc3c2)c1 CHEMBL1315803 Potency 7.9 nM
CCOC(=O)Cc1cc(C(=O)Nc2ccc(Br)cc2)sc1-c1ccc(C)cc1 CHEMBL1322763 Potency 7.9 nM
O=C(NC1CCCCC1)/C(=C/c1ccc(Cl)cc1)NC(=O)c1ccccc1 CHEMBL1552879 Potency 7.9 nM
COc1cc(NC(=O)Cc2c(C(=O)O)c(C)cn2C)cc(OC)c1 CHEMBL1555651 Potency 7.9 nM
O=C(CC1Oc2ccccc2NC1=O)NCc1ccc(F)cc1 CHEMBL1400340 Potency 7.9 nM
Cc1ccc(C(=O)Nc2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1 CHEMBL1475232 Potency 7.9 nM
CCc1ccc(CNC(=O)c2cc3cc(S(=O)(=O)N4CCCCC4)ccc3n2C)cc1 CHEMBL1374262 Potency 7.9 nM
O=C(Nc1ccc2oc(-c3ccc4ccccc4c3)nc2c1)c1ccc(Cl)c(Cl)c1 CHEMBL1527185 Potency 7.9 nM
Cc1cccc(Nc2nc(C)nc(N)c2S(=O)(=O)c2ccccc2)c1 CHEMBL1436876 Potency 7.9 nM
CCCCNc1nc(Oc2ccc(OCC(N)=O)nn2)nc(N2CCOCC2)n1 CHEMBL1446937 Potency 7.9 nM
Oc1ccc(-c2nc3ccccn3c2Nc2ccc3c(c2)OCCO3)cc1 CHEMBL1527850 Potency 7.9 nM
COc1ccc(C2C(C(N)=O)=C(C)Nc3nc(CCCO)nn32)c(OC)c1 CHEMBL1406722 Potency 7.9 nM
CCN(CC)S(=O)(=O)c1nnc(NC(=O)COc2ccc(Cl)cc2)s1 CHEMBL1513172 Potency 7.9 nM
Cc1ccc(C2c3[nH]c4ccccc4c3CCN2C(=O)CSc2ccccc2)cc1 CHEMBL1556334 Potency 7.9 nM
Cc1ccc(NC(=O)C2CC(=O)N(c3ccc(OC(C)C)cc3)C2)cc1 CHEMBL1444871 Potency 7.9 nM
CCCOc1ccc(/C=C/C(=O)Nc2sc3c(c2C(=O)OCC)CCC(C)C3)cc1OC CHEMBL1571188 Potency 7.9 nM
COc1ccc(NC(=O)c2ccco2)cc1NC(=O)C(C)(C)Oc1ccc(Cl)cc1 CHEMBL1553570 Potency 7.9 nM
O=C(CCn1c(=O)c2cccn2c2ccc(F)cc21)NCc1ccccc1F CHEMBL1318378 Potency 7.9 nM
COc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)c1 CHEMBL1551876 Potency 7.9 nM
COc1ccc(-c2nc3cc(NC(=O)CSc4ccc(C)cc4)ccc3o2)cc1 CHEMBL1356313 Potency 7.9 nM
CC(=O)c1ccc(NS(=O)(=O)c2ccc(-c3cnc(C4CC4)o3)cc2)cc1 CHEMBL1401552 Potency 7.9 nM
COc1ccc(Nc2nc3ccc(Cl)cc3nc2-n2nc(C)cc2C)cc1 CHEMBL1435491 Potency 7.9 nM
Fc1ccc(-n2ncc3c(NC4CCCCCC4)ncnc32)cc1 CHEMBL1442813 Potency 7.9 nM
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(S(=O)(=O)c4ccc(NC(=O)OC)cc4)CC3)cc21 CHEMBL1384345 Potency 7.9 nM
Cc1cc(SCC(=O)NC(=O)NCc2ccco2)nc2ccccc12 CHEMBL1304530 Potency 7.9 nM
CCOC(=O)N1CCC(NC(=O)c2ccc3c(c2)N(C)CCS3)CC1 CHEMBL1541466 Potency 7.9 nM
CN1[C@H]2C[C@H](OC(=O)[C@H](CO)c3ccccc3)C[C@H]1[C@H]1O[C@H]12 CHEMBL2373611 Potency 7.9 nM
CC(=O)Nc1cc(C(=O)NCc2ccccc2)ccc1Sc1ccc(C)cc1 CHEMBL1557416 Potency 7.9 nM
Cc1ccc2cccc(NC(=O)c3ccc(-c4cc(Cl)ccc4Cl)o3)c2n1 CHEMBL1324344 Potency 7.9 nM
COc1cccc(N2C(=O)CC(N3CCC(C(N)=O)(N4CCCCC4)CC3)C2=O)c1 CHEMBL1452394 Potency 7.9 nM
Cc1ccc(S(=O)(=O)NCC2CCC(C(=O)NCCCN3CCOCC3)CC2)cc1 CHEMBL1335426 Potency 7.9 nM
C[C@@H]1O[C@H](O[C@@H]2C=C3CC[C@H]4[C@@H](CC[C@]5(C)[C@@H](c6ccc(=O)oc6)CC[C@]45O)[C@@]3(C)CC2)[C@@H](O)[C@H](O)[C@@H]1O CHEMBL1394937 Potency 7.9 nM
C=C(C)C1CC=C(C)C(O)C1 CHEMBL1385229 Potency 7.9 nM
CCCCCOC(=O)c1ccccc1C(=O)OCCCCC CHEMBL1503330 Potency 7.9 nM
O=C(O[C@@H](C(=O)O)[C@@H](OC(=O)c1ccccc1)C(=O)O)c1ccccc1 CHEMBL1464055 Potency 7.9 nM
Cc1cn2c(=O)cc(COc3ccc(NC(=O)c4ccccc4C)cc3)nc2s1 CHEMBL1400882 Potency 7.9 nM
Cc1c(C(=O)Nc2cccc(C(F)(F)F)c2)oc2ccc(S(=O)(=O)N(C)C3CCCCC3)cc12 CHEMBL1512680 Potency 7.9 nM
CCOc1ccc(NC(=O)c2ccc3nc(C(C)C)oc3c2)cc1 CHEMBL1396518 Potency 7.9 nM
Nc1ccc(-c2ccc(N)cc2)cc1 CHEMBL15901 Potency 7.9 nM
O=C(CS(=O)(=O)c1cccc2nsnc12)N1CCN(c2cccc(C(F)(F)F)c2)CC1 CHEMBL1514877 Potency 7.9 nM
CCOC(=O)c1c(NC(=O)COc2cc(C)ccc2C(C)C)sc2c1CCCC2 CHEMBL1530447 Potency 7.9 nM
Cc1ccc(-n2ncc3c(NCCCc4ccccc4)ncnc32)cc1 CHEMBL1314497 Potency 7.9 nM
COc1ccc(C2CC(=O)Nc3c2c(=O)nc2c(C)cccn32)cc1 CHEMBL1437774 Potency 7.9 nM
CCOCCCNC(=O)c1[nH]c(C)c(C(C)=O)c1C CHEMBL1376858 Potency 7.9 nM
Cc1ccc(-n2nc3ccc(NC(=O)COc4ccccc4C)cc3n2)cc1 CHEMBL1612418 Potency 7.9 nM
Cc1cc(C)n(S(=O)(=O)c2cc(Cl)ccc2Cl)n1 CHEMBL1536294 Potency 7.9 nM
CCCS(=O)(=O)NCCc1cc2cc(C)c(C)cc2nc1O CHEMBL1536265 Potency 7.9 nM
Cc1cccc(N2CCN(C(=O)c3c(C)oc4ncnc(N5CCOCC5)c34)CC2)c1C CHEMBL1413428 Potency 7.9 nM
Cc1cc(C)n2nc3nc(N4CCCC4)nc(-c4ccccc4)c3c2n1 CHEMBL1561450 Potency 7.9 nM
CCOc1cccc(N)c1 CHEMBL1466168 Potency 7.9 nM
N=C(NCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1)NC(=N)Nc1ccc(Cl)cc1 CHEMBL790 Potency 7.9 nM
Cc1ccc2c(c1)c1c(c(=O)n(-c3cccc(Cl)c3)c(=O)n1CC(=O)N1CCCC1)n2C CHEMBL1474365 Potency 7.9 nM
NC(=O)C1CCN(CC(=O)Nc2cccc(C(=O)Nc3cccc(C(F)(F)F)c3)c2)CC1 CHEMBL1420443 Potency 7.9 nM
CCN(CC)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)N1CCc3ccccc3C1)cn2C CHEMBL1417779 Potency 7.9 nM
COc1ccc(C)cc1NC(=O)C1CCC(CNS(=O)(=O)c2ccc3c(c2)CCCC(=O)N3)CC1 CHEMBL1473034 Potency 7.9 nM
Cc1ccc(-c2nc(C)c(CCNC(=O)C(=O)Nc3ccc(C)c(Cl)c3)s2)cc1 CHEMBL1592169 Potency 7.9 nM
O=C(c1cccc(F)c1)N1CCC(c2c[nH]c3ccccc23)(c2c[nH]c3ccccc23)CC1 CHEMBL1318160 Potency 7.9 nM
NC(=O)CSc1oc(-c2cccs2)nc1S(=O)(=O)c1ccc(Br)cc1 CHEMBL1535735 Potency 7.9 nM
COc1ccc(S(=O)(=O)N(CC(=O)Nc2ccc(F)c(Cl)c2)c2ccc(C)cc2)cc1OC CHEMBL1553690 Potency 7.9 nM
Cc1ccc(-c2csc3ncnc(Nc4ccc(C(=O)O)cc4)c23)cc1 CHEMBL1513159 Potency 7.9 nM
Cc1c(C(=O)c2cccc3ccccc23)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL1222317 Potency 7.9 nM
O=C(Cn1c(=O)n(-c2ccc(F)c(Cl)c2)c(=O)c2sc3ccccc3c21)NC1CCCC1 CHEMBL1378891 Potency 7.9 nM
O=C(CCNS(=O)(=O)c1cccs1)N1CCCCCC1 CHEMBL1518168 Potency 7.9 nM
CCCc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)C3CCCCC3)nc2s1 CHEMBL1556081 Potency 7.9 nM
CCc1ccc(CNC(=O)Cn2nc(-c3ccc(C)cc3)ccc2=O)cc1 CHEMBL1447785 Potency 7.9 nM
Cc1ccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)N4CCC5(CC4)OCCO5)cc32)cc1 CHEMBL1520611 Potency 7.9 nM
COC(=O)c1cc2oc(C)cc2n1CC(=O)Nc1cc(Cl)ccc1OC CHEMBL1326571 Potency 7.9 nM
CC1CC(C)CN(CCCNC(=O)C2CCCN(c3nnc(N4CCCC4=O)s3)C2)C1 CHEMBL1390695 Potency 7.9 nM
Cc1ccc(CNC(=O)CN2N=C(c3ccccc3)CCC2=O)cc1 CHEMBL1566979 Potency 7.9 nM
CCCCOc1ccccc1NC(=O)CC1Sc2ccccc2NC1=O CHEMBL1484852 Potency 7.9 nM
COc1ccccc1NC(=O)C1=C(C)Nc2nc(SCc3cc(C)ccc3C)nn2C1c1ccccc1 CHEMBL1435263 Potency 7.9 nM
O=C1c2ccccc2-c2onc3ccc(Oc4ccccc4)c1c23 CHEMBL1558210 Potency 7.9 nM
Cc1nnc(NC(=O)C2C3C=CC(O3)C2C(=O)O)s1 CHEMBL1446100 Potency 7.9 nM
COc1ccc(-n2nc(C(=O)Nc3cccc(C(F)(F)F)c3)c3c4ccccc4n(C)c3c2=O)cc1 CHEMBL1330897 Potency 7.9 nM
Cc1ccc(CNC(=O)CN2C(=O)C3CCCCN3c3ccc(C(=O)N4CCCC4)cc32)cc1 CHEMBL1355607 Potency 7.9 nM
CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCN(C(C)C)C3)cc1 CHEMBL1598836 Potency 7.9 nM
Cc1ccc(-n2c(SCC(N)=O)nc3c(oc4ccccc43)c2=O)cc1C CHEMBL1315608 Potency 7.9 nM
COC(=O)c1ccc(OCC2c3cc(OC)c(OC)cc3CCN2C(=O)c2ccccc2C)cc1 CHEMBL1327290 Potency 7.9 nM
COc1ccc(N(CC(=O)Nc2cc(Cl)ccc2OC)S(=O)(=O)c2c(C)noc2C)cc1 CHEMBL1440659 Potency 7.9 nM
COc1ccc(CNC(=O)CCc2nc(-c3ccccc3F)no2)c(OC)c1 CHEMBL1579103 Potency 7.9 nM
NCCNCCNCCNCCN CHEMBL138297 Potency 7.9 nM
COc1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)c(C)c1 CHEMBL1434846 Potency 7.9 nM
COCCn1c(CNC(=O)c2cccc(C)c2)nc2cccnc21 CHEMBL1524888 Potency 7.9 nM
CCNCC CHEMBL1189 Potency 7.9 nM
CCC12CN3CC(CC)(CN(C1)C3c1c(C)[nH]c(=O)[nH]c1=O)C2=O CHEMBL1396571 Potency 8.9 nM
O=c1[nH]c2cc(Br)ccc2n2cccc12 CHEMBL1231450 Potency 8.9 nM
O=C1NC2c3ccccc3C(=O)N2c2c1cnn2-c1ccccc1 CHEMBL1338190 Potency 8.9 nM
O=S(=O)(CCn1cccc1)CCn1cccc1 CHEMBL1407159 Potency 8.9 nM
COc1cccc(CNC(=O)Cn2c(SCC(=O)Nc3ccc(F)cc3)nc3ccccc32)c1 CHEMBL1515006 Potency 8.9 nM
COc1ccc(Cl)cc1NS(=O)(=O)c1ccc(OC)c(OC)c1 CHEMBL1609549 Potency 8.9 nM
COCCSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccc(OC)c(OC)c1 CHEMBL1394500 Potency 8.9 nM
CCc1ccccc1NC(=O)Nc1cc(C(=O)NCc2cccc(F)c2)ccc1N1CCCC1 CHEMBL1522212 Potency 8.9 nM
CCCCN1C(=O)N(C)C2C1N(C)C(=O)N2CCCC CHEMBL1559076 Potency 8.9 nM
COc1ccc(CCNC(=O)c2cc(-c3ccc(C)c(C)c3)nc3ccccc23)cc1OC CHEMBL1473561 Potency 8.9 nM
COc1ccccc1C1CC(c2ccco2)=NN1c1ccccc1 CHEMBL1338205 Potency 8.9 nM
CNC(=S)N/N=C/c1ccc(OCC(=O)Nc2c(C)cc(C)cc2C)c(OC)c1 CHEMBL3192989 Potency 8.9 nM
Cc1cc(C=C2C(=O)CCCC2=O)c(C)n1-c1ccccc1 CHEMBL1433049 Potency 8.9 nM
CCc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCNC(C)=O)cc1 CHEMBL1551744 Potency 8.9 nM
CCOc1ccc(CNCc2cccnc2)cc1 CHEMBL1307141 Potency 8.9 nM
CCc1ccccc1NC(=O)N(C)CCc1c(C)nn(C)c1C CHEMBL1377197 Potency 8.9 nM
Cc1ccc(/C=C(\C#N)C(=O)Nc2cccc(Br)c2)o1 CHEMBL1491122 Potency 8.9 nM
Cc1nn(-c2ccc(F)cc2)c(Cl)c1/C=N/NC(=O)c1cccs1 CHEMBL3198641 Potency 8.9 nM
CC(Sc1nc(-c2ccc(F)cc2)cs1)C(=O)N1c2ccccc2CC1C CHEMBL1348501 Potency 8.9 nM
O=C(Cn1cc(C(=O)c2ccco2)c2ccccc21)Nc1ccc(Br)cc1 CHEMBL1436533 Potency 8.9 nM
CCOc1ccc(NC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 CHEMBL1513822 Potency 8.9 nM
Cc1cccc(NC(=O)Cn2cc(C(=O)c3ccco3)c3ccccc32)c1 CHEMBL1557815 Potency 8.9 nM
COc1ccc(CCN2CC(C(=O)NCCc3ccc(C)cc3)CC2=O)cc1OC CHEMBL1329888 Potency 8.9 nM
O=C(COc1ccc(Br)cc1)Nc1cccc2cccnc12 CHEMBL1434464 Potency 8.9 nM
COC(=O)c1c(NC(=O)C2COc3ccccc3O2)sc2c1CCN(Cc1ccccc1)C2 CHEMBL1577933 Potency 8.9 nM
Cc1cc(Br)cc2c(C(=O)OCC(=O)c3ccccc3)cc(-c3ccccc3)nc12 CHEMBL1314681 Potency 8.9 nM
CCOc1ccccc1NC(=O)CSc1nc2c(oc3ccccc32)c(=O)n1-c1ccc(F)cc1 CHEMBL1605053 Potency 8.9 nM
COc1ccc2oc3cc(C)[n+]([O-])c(-c4ccc(Br)cc4)c3c2c1 CHEMBL1477674 Potency 8.9 nM
COc1cc2c(cc1NC(=O)COC(=O)/C=C/c1ccccc1)oc1ccccc12 CHEMBL1350224 Potency 8.9 nM
COc1ccc(NC(=O)CSc2nc3cc(OC)c(OC)cc3c3nc(-c4ccccc4)nn23)cc1Cl CHEMBL1330328 Potency 8.9 nM
Cc1cccc(-n2c(/C=C/c3cn(C)c4ccccc34)nc3ccccc3c2=O)c1 CHEMBL1449683 Potency 8.9 nM
COc1ccc(N2CCN(C(=O)c3c(C)oc4nc(C)nc(N5CCCC5)c34)CC2)cc1 CHEMBL1394110 Potency 8.9 nM
COc1ccc(NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc3c2CCCCC3)cc1 CHEMBL1435471 Potency 8.9 nM
c1ccc(NCc2nc3ccccc3n2CCOc2ccccc2)cc1 CHEMBL1423635 Potency 8.9 nM
COc1ccc2c(c1)CCCN2S(=O)(=O)c1ccc(N2CCCC2=O)cc1 CHEMBL4243509 EC50 9.0 nM