Nc1nc(O[C@H](c2ccc(Cl)cc2-c2ccccc2)C(F)(F)F)cc(N2CCC3(CC2)CN[C@H](C(=O)O)C3)n1 CHEMBL4104957 IC50 7.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccsc3n1)n2Cc1ccccc1 CHEMBL5395489 IC50 11.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc4c(cc3[nH]1)OCO4)n2Cc1ccccc1 CHEMBL5191481 IC50 14.0 nM
CCCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc4c(cc3[nH]1)OCO4)n2Cc1ccccc1 CHEMBL5173430 IC50 14.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccsc3n1)n2Cc1ccc(-c2ccn(C)n2)cc1 CHEMBL5416480 IC50 14.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(Cl)sc3n1)n2Cc1ccccc1 CHEMBL5424626 IC50 15.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccccc1 CHEMBL5397485 IC50 16.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccc(NC(C)=O)cc1 CHEMBL5407430 IC50 16.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CC1COC1 CHEMBL5404510 IC50 16.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(-c2ccn(C)n2)cc1 CHEMBL5420432 IC50 17.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccc(N2CCCC2=O)cc1 CHEMBL5423163 IC50 17.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(-c2nccs2)cc1 CHEMBL5435460 IC50 17.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(Cl)sc3n1)n2Cc1ccc(NC(C)=O)cc1 CHEMBL5394253 IC50 17.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3nc(C)sc3n1)n2Cc1ccccc1 CHEMBL5408595 IC50 18.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(-c2noc(C)n2)cc1 CHEMBL5438521 IC50 18.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccccn1 CHEMBL5438308 IC50 18.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3ccccc3[nH]1)n2Cc1ccccc1 CHEMBL5169479 IC50 19.0 nM
CCCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3ccccc3[nH]1)n2Cc1ccccc1 CHEMBL5203888 IC50 20.0 nM
CCCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc(O)ccc3[nH]1)n2Cc1ccccc1 CHEMBL5197055 IC50 20.0 nM
CCOc1ccc2[nH]c(Cc3nc4c(c(=O)[nH]c(=O)n4CC)n3Cc3ccccc3)nc2c1 CHEMBL5172829 IC50 20.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(-c2nc(C)no2)cc1 CHEMBL5413997 IC50 20.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(-c2ncccn2)cc1 CHEMBL5420586 IC50 20.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(C(=O)OC)cc1 CHEMBL5421387 IC50 20.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccc(-c2ccn(C)n2)cc1 CHEMBL5423736 IC50 21.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1cccc(C(=O)OC)c1 CHEMBL5399835 IC50 22.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(Cl)sc3n1)n2Cc1ccc(-n2cncn2)cc1 CHEMBL5407978 IC50 23.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CC1CC1 CHEMBL5436189 IC50 23.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(Cl)sc3n1)n2Cc1ccc(-c2ccn(C)n2)cc1 CHEMBL5440400 IC50 24.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1cccc(C)n1 CHEMBL5438753 IC50 24.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2C(C)C CHEMBL5415902 IC50 24.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1cccc(C(=O)OC)c1 CHEMBL5413327 IC50 25.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccc(OC)cc1 CHEMBL5416684 IC50 25.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(-c2noc(C)n2)cc1 CHEMBL5404599 IC50 26.0 nM
CCOC(=O)CCCn1c(Cc2cn3cc(C)sc3n2)nc2c1c(=O)[nH]c(=O)n2CC CHEMBL5435257 IC50 26.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(-n2ccnc2)cc1 CHEMBL5396844 IC50 29.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(-c2ccn(C)n2)cc1 CHEMBL5426838 IC50 30.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(N2CCCC2=O)cc1 CHEMBL5437935 IC50 30.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc2c(c1)OCO2 CHEMBL5424419 IC50 30.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(-n2cncn2)cc1 CHEMBL5423548 IC50 31.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CC1CCC1 CHEMBL5430916 IC50 31.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(N2CC(F)(F)C2)cc1 CHEMBL5440685 IC50 32.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2CC1CCC1 CHEMBL5394907 IC50 32.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CC=C(C)C CHEMBL5397488 IC50 32.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1cc(C)cc(C)c1 CHEMBL5438647 IC50 34.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(N2CC(OC)C2)cc1 CHEMBL5394249 IC50 35.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(NC(C)=O)cc1 CHEMBL5403466 IC50 36.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(Cl)sc3n1)n2CC1COC1 CHEMBL5416130 IC50 37.0 nM
CCOC(=O)Cn1c(Cc2cn3cc(C)sc3n2)nc2c1c(=O)[nH]c(=O)n2CC CHEMBL5413920 IC50 37.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(CC(=O)OC)cc1 CHEMBL5431552 IC50 38.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CCCOC CHEMBL5398093 IC50 38.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccc(-c2ccccc2)cc1 CHEMBL5398162 IC50 39.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccc(F)cc1 CHEMBL5424884 IC50 39.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1ccccc1 CHEMBL5424818 IC50 40.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1cccc(C(F)(F)F)c1 CHEMBL5438865 IC50 41.0 nM
CCCn1c(=O)[nH]c(=O)c2c1nc(Sc1nc3ccccc3[nH]1)n2Cc1ccccc1 CHEMBL5182871 IC50 43.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccccc1 CHEMBL5434335 IC50 43.0 nM
CCCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccccc1 CHEMBL5424846 IC50 45.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Sc1nc3ccccc3[nH]1)n2Cc1ccccc1 CHEMBL5192356 IC50 47.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc(N(C)C)c(F)cc3[nH]1)n2Cc1ccccc1 CHEMBL5176333 IC50 50.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3nc4cc5c(cc4[nH]3)OCO5)n(Cc3ccccc3)c12 CHEMBL5200474 IC50 51.0 nM
CCc1nc(C)ccc1OCC(=O)N1CCc2nc3n(c2C1c1ccc(Cl)cc1F)CCCC3 CHEMBL5408404 IC50 51.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1ccc(C(F)(F)F)cc1 CHEMBL5411613 IC50 52.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2CC1COC1 CHEMBL5421206 IC50 57.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CCC(=O)OC CHEMBL5415966 IC50 57.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2Cc1cccc(C(=O)O)c1 CHEMBL5420292 IC50 58.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1cccc(C(=O)NC[C@H](N)C(=O)OC)c1 CHEMBL5414714 IC50 58.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3nc4ccc(O)cc4[nH]3)n(Cc3ccccc3)c12 CHEMBL5178857 IC50 60.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc(N4CCOCC4)c(F)cc3[nH]1)n2Cc1ccccc1 CHEMBL5174736 IC50 60.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3cn4ccccc4n3)n(Cc3ccccc3)c12 CHEMBL5417752 IC50 61.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1cccc(C(=O)NC[C@H](NC(=O)OCc2ccccc2)C(=O)OC)c1 CHEMBL5421152 IC50 63.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CCCC(=O)O CHEMBL5412796 IC50 69.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3nc4ccccc4[nH]3)n(Cc3ccccc3)c12 CHEMBL5173528 IC50 70.0 nM
COc1ccc2nc(Cc3nc4c(c(=O)[nH]c(=O)n4C4CC4)n3Cc3ccccc3)[nH]c2c1 CHEMBL5208772 IC50 70.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(CCO)cc1 CHEMBL5420781 IC50 71.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(-c2ccc(C(F)(F)F)cn2)cc1 CHEMBL5434435 IC50 76.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(Cl)sc3n1)n2Cc1ccc(N2CC(F)(F)C2)cc1 CHEMBL5396849 IC50 96.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3nc4cc(N5CCOCC5)ccc4[nH]3)n(Cc3ccccc3)c12 CHEMBL5180953 IC50 100.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CCC=C(C)C CHEMBL5435958 IC50 116.0 nM
COC(=O)c1ccc2nc(Cc3nc4c(c(=O)[nH]c(=O)n4C4CC4)n3Cc3ccccc3)[nH]c2c1 CHEMBL5183954 IC50 140.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3nc4ccc(OCCO)cc4[nH]3)n(Cc3ccccc3)c12 CHEMBL5198260 IC50 140.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3cc(C)sc3n1)n2CC1CCCCC1 CHEMBL5435077 IC50 152.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc(N4CCOCC4)ccc3[nH]1)n2Cc1ccccc1 CHEMBL5204911 IC50 170.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3cc(NC(=O)CC[C@H](N)C(=O)O)ccc3[nH]1)n2Cc1ccccc1 CHEMBL5172824 IC50 170.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1cccc(C(=O)NC[C@H](N)C(=O)O)c1 CHEMBL5435288 IC50 176.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Sc1nc3cc(NC(=O)CC[C@H](N)C(=O)O)ccc3[nH]1)n2Cc1ccccc1 CHEMBL5195178 IC50 230.0 nM
O=c1[nH]c(=O)n(C2CC2)c2nc(Cc3nc4ccc(F)cc4[nH]3)n(Cc3ccccc3)c12 CHEMBL5183282 IC50 230.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3ccccc3n1)n2Cc1ccc(C(=O)O)cc1 CHEMBL5430067 IC50 272.0 nM
CCn1c(=O)[nH]c(=O)c2c1nc(Cc1cn3c(n1)CCCC3)n2Cc1cccc(C(=O)O)c1 CHEMBL5430684 IC50 307.0 nM
N#Cc1ccc2nc(Cc3nc4c(c(=O)[nH]c(=O)n4C4CC4)n3Cc3ccccc3)[nH]c2c1 CHEMBL5183966 IC50 450.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Sc1nc3cc(N)ccc3[nH]1)n2Cc1ccccc1 CHEMBL5183005 IC50 490.0 nM
Cc1ccc2[nH]c(Sc3nc4c(c(=O)[nH]c(=O)n4C)n3Cc3cncs3)nc2c1 CHEMBL5209431 IC50 490.0 nM
Cc1cccc(-c2ccccc2C(Oc2cc(-c3ccc(C[C@H](N)C(=O)O)cc3)nc(N)n2)C(F)(F)F)c1 CHEMBL471380 EC50 560.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3ccc(N)cc3[nH]1)n2Cc1ccccc1 CHEMBL5206155 IC50 690.0 nM
Cc1ccn(-c2cc(Cl)ccc2[C@@H](Oc2cc(-c3ccc(C[C@H](N)C(=O)O)cc3)nc(N)n2)C(F)(F)F)n1 CHEMBL2103855 IC50 710.0 nM
Nc1nc(OC(c2ccccc2-n2ccc(C(F)(F)F)n2)C(F)(F)F)cc(-c2ccc(C[C@H](N)C(=O)O)cc2)n1 CHEMBL479924 EC50 750.0 nM
CN1CCN(c2ccc3[nH]c(Cc4nc5c(c(=O)[nH]c(=O)n5C)n4Cc4ccccc4)nc3c2)CC1 CHEMBL5170266 IC50 760.0 nM
Nc1nc(OC(c2ccccc2-c2ccco2)C(F)(F)F)cc(-c2ccc(C[C@H](N)C(=O)O)cc2)n1 CHEMBL471564 EC50 800.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Cc1nc3ccccc3[nH]1)n2Cc1ccccc1 CHEMBL5176883 IC50 820.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Sc1nc3cc(NC(=O)C[C@H](N)C(=O)O)ccc3[nH]1)n2Cc1ccccc1 CHEMBL5190719 IC50 830.0 nM
Cn1c(=O)[nH]c(=O)c2c1nc(Sc1nc3ccccc3[nH]1)n2Cc1ccccc1 CHEMBL1736726 IC50 920.0 nM