CC(C)N(CCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21)C(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1 CHEMBL1910764 Kd(app) 5.8 nM
Nc1ncnc2c1nc(Sc1cc3c(cc1I)OCO3)n2CCCNC(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1 CHEMBL2419342 Kd(app) 5.9 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc(C(=O)NC(=N)N)cc1 CHEMBL4126250 Kd 10.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1 CHEMBL252164 Ki 16.0 nM
CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3c(ccn3C)c2)c(O)cc1O CHEMBL2103879 IC50 37.7 nM
CO[C@H]1/C=C\C=C(/C)C(=O)NC2=CC(=O)C(NCCCCNC(=O)Cc3ccc4c(c3)C(C)(C)C3=[N+]4CCC4OC5CCN6C(=C5C=C34)C(C)(C)c3cc(S(=O)(=O)[O-])ccc36)=C(C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@@H]1OC(N)=O)C2=O CHEMBL2419341 Kd(app) 51.8 nM
Nc1nc(Cl)c2nc(O)n(Cc3ccc(Br)cc3F)c2n1 CHEMBL4866705 IC50 58.0 nM
COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc32)c1C CHEMBL467399 Ki 62.0 nM
Cc1ccc(Cn2c(O)nc3c(Cl)nc(N)nc32)c(F)c1 CHEMBL4863672 IC50 62.4 nM
Nc1nc(Cl)c2nc(S)n(Cc3ccc(Cl)c(Cl)c3)c2n1 CHEMBL4864922 IC50 63.5 nM
Nc1nc(Cl)c2nc(O)n(Cc3cc4c(cc3Br)OCO4)c2n1 CHEMBL4869481 IC50 65.8 nM
Nc1nc(Cl)c2nc(O)n(Cc3ccc(Cl)c(Cl)c3)c2n1 CHEMBL4879021 IC50 76.6 nM
Nc1nc(Cl)c2cnn(Cc3cc4c(cc3Br)OCO4)c2n1 CHEMBL4068596 IC50 79.0 nM
Nc1nc(Cl)c2c(n1)N(Cc1ccc(Cl)c(Cl)c1)C(=O)C2 CHEMBL4866958 IC50 81.5 nM
Cc1ccc(Cn2c(S)nc3c(Cl)nc(N)nc32)c(F)c1 CHEMBL4876871 IC50 82.7 nM
Cc1ccc(CN2C(=O)Cc3c(Cl)nc(N)nc32)c(F)c1 CHEMBL4863988 IC50 89.9 nM
Nc1nc(Cl)c2c(n1)N(Cc1ccc(Br)cc1F)C(=O)C2 CHEMBL4871630 IC50 100.0 nM
COc1c(C)cnc(Cn2ncc3c(Cl)nc(N)nc32)c1C CHEMBL4080323 IC50 138.0 nM
Nc1nc(Cl)c2nc(O)n(Cc3cc(C(F)(F)F)ccc3Cl)c2n1 CHEMBL4857569 IC50 170.0 nM
COc1cc(F)c(Cn2c(S)nc3c(Cl)nc(N)nc32)c(F)c1 CHEMBL4860652 IC50 178.0 nM
CC(C)NCCCn1c(Sc2cc3c(cc2I)OCO3)nc2c(N)ncnc21 CHEMBL200102 IC50 192.0 nM
COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3C(=O)N2)n1 CHEMBL3360305 IC50 200.0 nM
COc1ccc(F)c(CN2C(=O)Cc3c(Cl)nc(N)nc32)c1F CHEMBL4850126 IC50 230.0 nM
Nc1nc(Cl)c2nc(O)n(Cc3cc(Cl)ccc3F)c2n1 CHEMBL4846028 IC50 243.0 nM
COc1c(C)cnc(Cn2cc(C#CCC(C)(C)O)c3c(Cl)nc(N)nc32)c1C CHEMBL1230584 Ki 255.0 nM
Nc1nc(Cl)c2c(n1)N(Cc1cc3c(cc1Br)OCO3)C(=O)C2 CHEMBL4870087 IC50 296.0 nM
CO[C@H]1C[C@H](C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)/C(C)=C/C=C\[C@@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@H]1O)C2=O CHEMBL3104859 Ki 326.0 nM
COc1cccc(CN2C(=O)Cc3c(Cl)nc(N)nc32)c1OC CHEMBL4854861 IC50 331.0 nM
Nc1nc(Cl)c2nc(S)n(Cc3ccc(Br)cc3F)c2n1 CHEMBL4864235 IC50 332.0 nM
Nc1nc(Cl)c2c(n1)N(Cc1ccc3c(c1)OCO3)C(=O)C2 CHEMBL4867384 IC50 339.0 nM
Nc1nc(Cl)c2cnn(Cc3ccc(Br)cc3F)c2n1 CHEMBL5266569 IC50 373.0 nM
Nc1nc(Cl)c2nc(S)n(Cc3c(F)ccc(F)c3F)c2n1 CHEMBL4865186 IC50 392.0 nM
CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc(OC)cc1 CHEMBL1941052 IC50 400.0 nM
Nc1nc(Cl)c2nc(S)n(Cc3ccc(C(F)(F)F)cc3)c2n1 CHEMBL4872173 IC50 413.0 nM
Nc1nc(Cl)c2nc(N)n(Cc3ccc(Br)cc3F)c2n1 CHEMBL4859919 IC50 477.0 nM
CCNC(=O)C1=C(c2ccc(CN3CCOCC3)cc2)/C(=C2\C=C(C(C)C)C(O)=CC2=O)ON1 CHEMBL3900791 IC50 500.0 nM
Nc1nc(Cl)c2nc(S)n(Cc3ccc(F)c(Cl)c3)c2n1 CHEMBL4853048 IC50 590.0 nM
Nc1nc(Cl)c2nc(N)n(Cc3cc4c(cc3Br)OCO4)c2n1 CHEMBL4853988 IC50 617.0 nM
COC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(/C)C(=O)NC(=CC1=O)C2=O CHEMBL278315 IC50 661.0 nM
CC1(C)CC(=O)c2c(C(F)(F)F)nn(-c3ccc(C(N)=O)c(N[C@H]4CC[C@H](O)CC4)c3)c2C1 CHEMBL560895 IC50 726.0 nM
Nc1nc(Cl)c2nc(O)n(Cc3ccc(F)c(Cl)c3)c2n1 CHEMBL4870476 IC50 728.0 nM
Nc1nc(Cl)c2nc(S)n(Cc3cc4c(cc3Br)OCO4)c2n1 CHEMBL4870579 IC50 738.0 nM
Nc1ncnc2c1nc(Sc1cc3c(cc1I)OCO3)n2CCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL4641095 IC50 794.0 nM
Nc1ncnc2c1nc(Sc1cc3c(cc1I)OCO3)n2CCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1 CHEMBL4649057 IC50 872.0 nM