CCCOc1cc(OCCCCN(C)C)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 CHEMBL3774575 Kd 1.3 nM
CCCOc1cc(OCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)cn2)n(C)c(=O)n3C)c1 CHEMBL3775251 IC50 7.9 nM
CCCOc1cc(OCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 CHEMBL3774933 IC50 8.3 nM
CCCOc1cc(OCCCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)cn2)n(C)c(=O)n3C)c1 CHEMBL3775901 IC50 10.0 nM
CCCOc1cc(OCCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)cn2)n(C)c(=O)n3C)c1 CHEMBL3775348 IC50 11.0 nM
CCCOc1cc(OCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 CHEMBL3774542 IC50 13.0 nM
CCCOc1cc(OCCCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 CHEMBL3774766 IC50 13.0 nM
CCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 CHEMBL3775853 IC50 43.0 nM
CCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)c(C)n2)n(C)c(=O)n3C)c1 CHEMBL3775073 IC50 53.0 nM
Cc1nc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCC(C)C)c2)n(C)c(=O)n3C)cn1C CHEMBL3774507 IC50 57.0 nM
CCCOc1cc(OCCCCCCO)cc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)cn2)n(C)c(=O)n3C)c1 CHEMBL3774770 IC50 60.0 nM
Cn1cnc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCC4CCOC4)c2)n(C)c(=O)n3C)c1 CHEMBL3775689 IC50 100.0 nM
CC(C)COc1cccc(Oc2cc3c(cc2NS(=O)(=O)C2CC2)n(C)c(=O)n3C)c1 CHEMBL3775132 IC50 110.0 nM
COCCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)c(C)n2)n(C)c(=O)n3C)c1 CHEMBL3774529 IC50 130.0 nM
O=Cc1ccc(N2CCCC2)cc1 CHEMBL4572394 IC50 133.4 nM
O=C1CCCC1 CHEMBL18620 IC50 135.8 nM
COc1ccc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCc4ccccc4)c2)n(C)c(=O)n3C)cc1OC CHEMBL3775263 IC50 140.0 nM
Cc1cccc2c(C=O)c[nH]c12 CHEMBL4467793 IC50 156.6 nM
CCCOc1cc(OCCCCCCNC(=O)OC(C)(C)C)cc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)cn2)n(C)c(=O)n3C)c1 CHEMBL3774638 IC50 160.0 nM
CCCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)c(C)n2)n(C)c(=O)n3C)c1 CHEMBL3774452 IC50 160.0 nM
COc1cc(C=O)ccc1O CHEMBL13883 IC50 162.0 nM
O=Cc1cccc(-c2ccc(C(=O)O)cc2)c1 CHEMBL4592980 IC50 164.8 nM
O=C1CCCCCCC1 CHEMBL18737 IC50 166.3 nM
CCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2cn(C)c(C)n2)n(C)c(=O)n3C)c1 CHEMBL3774653 IC50 180.0 nM
Cn1cccc1C=O CHEMBL2229659 IC50 180.2 nM
COc1ccc(C=O)c(O)c1 CHEMBL350966 IC50 219.7 nM
Cn1cnc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCc4ccccc4)c2)n(C)c(=O)n3C)c1 CHEMBL3775286 IC50 220.0 nM
O=Cc1ccccc1O CHEMBL108925 IC50 221.3 nM
COc1ccc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)cc1 CHEMBL3769965 Kd 222.0 nM
Cc1ncc(CO)c(C=O)c1O CHEMBL543846 IC50 225.2 nM
COc1ccc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCCCCN(C)C)c2)n(C)c(=O)n3C)cc1OC CHEMBL3774883 IC50 270.0 nM
Cc1nc(S(=O)(=O)Nc2cc3c(cc2Oc2cccc(OCc4ccccc4)c2)n(C)c(=O)n3C)cn1C CHEMBL3775640 IC50 270.0 nM
Cc1nc[nH]c1-c1nc2ccc(C(=O)NN)cn2c1NCCN1CCOCC1 CHEMBL4580867 IC50 303.5 nM
COC(=O)c1ccc2nc(-c3nc[nH]c3C)c(NCCN3CCOCC3)n2c1 CHEMBL4470369 IC50 308.2 nM
CCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2cccc(C(=O)NCCOCCOCCOCC(=O)N[C@@H](C(=O)N4C[C@@H](O)C[C@@H]4C(=O)NCc4ccc(-c5scnc5C)cc4)C(C)(C)C)c2)n(C)c(=O)n3C)c1 CHEMBL5276376 IC50 337.7 nM
COc1ccc(Nc2c(-c3nc[nH]c3C)nc3ccccn23)cc1 CHEMBL4446283 IC50 356.0 nM
COC(=O)c1ccc2nc(-c3cn(S(=O)(=O)c4ccc(C)cc4)c4ccccc34)c(NCc3ccccc3)n2c1 CHEMBL4451080 IC50 415.3 nM
COc1ccc(S(=O)(=O)Nc2cc3c(cc2Oc2ccccc2)n(C)c(=O)n3C)cc1OC CHEMBL3769887 IC50 480.0 nM
COc1ccc(CCNc2c(-c3cn(S(=O)(=O)c4ccc(C)cc4)c4ccccc34)nc3ccccn23)cc1OC CHEMBL4452179 IC50 584.2 nM
COc1ccc(Oc2cc3c(cc2NS(=O)(=O)c2ccccc2)n(C)c(=O)n3C)cc1 CHEMBL3770259 IC50 730.0 nM
COc1ccc(S(=O)(=O)Nc2cc3c(cc2Oc2ccccc2)n(C)c(=O)n3C)cc1 CHEMBL3771002 IC50 740.0 nM
Cc1[nH]cnc1-c1nc2ccccn2c1NCCN1CCOCC1 CHEMBL4461534 IC50 746.4 nM
COc1ccc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)cc2)n(C)c(=O)n3C)cc1 CHEMBL3770456 IC50 770.0 nM
COc1ccc(Nc2c(-c3c[nH]c(C)n3)nc3ccc(Br)cn23)cc1 CHEMBL4448530 IC50 818.3 nM
CN(C)C(=O)c1cccc(-c2cn(C)c(=O)c3[nH]ccc23)c1 CHEMBL4436408 IC50 910.0 nM
COc1ccc(C2CC2)cc1S(=O)(=O)Nc1ccc2c(c1)CCN2C(C)=O CHEMBL5196972 IC50 980.0 nM