Cn1c(=O)n(CCCO)c(=O)c2c1nc(Oc1cccc(Cl)c1)n2Cc1ccc(Cl)cc1 CHEMBL4546097 IC50 0.52 nM
Cn1c(=O)n(CCCO)c(=O)c2c1nc(Oc1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1 CHEMBL4466522 IC50 1.3 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)sc21 CHEMBL3945449 IC50 1.84 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(-c3cccc(OC(F)(F)F)c3)sc21 CHEMBL3920228 IC50 1.91 nM
CC(C)Oc1ccc2c(c1Cc1ccc(F)cc1)c(=O)n(CCCO)c(=O)n2C CHEMBL4466158 IC50 2.64 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccccc3)c(Oc3cccc(OC(F)(F)F)c3)ccc21 CHEMBL4525688 IC50 2.69 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccccc3)c(-c3cccc(OC(F)(F)F)c3)ccc21 CHEMBL4451083 IC50 5.3 nM
CC(C)[C@@]12C[C@@H](OC(=O)CO)[C@@](C)(O1)[C@@H]1CC[C@@H](C)[C@H]1[C@@H]2OC(=O)/C=C/c1ccccc1 CHEMBL2024567 EC50 7.59 nM
COc1ccc2c(c1Cc1ccc(F)cc1)c(=O)n(CCCO)c(=O)n2C CHEMBL4562137 IC50 8.37 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3ccc(F)cc3C(F)(F)F)C2)=C1Cl CHEMBL5201831 IC50 14.07 nM
Cc1c(-c2ccc(Cl)cc2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3948028 IC50 15.7 nM
COc1ccc2c(c1Cc1ccccc1)c(=O)n(CCCO)c(=O)n2C CHEMBL4464289 IC50 23.3 nM
Cc1c(-c2ccccc2Cl)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3928277 IC50 27.0 nM
Cc1c(-c2cccc(F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3942647 IC50 27.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(-c3cccc(Cl)c3)sc21 CHEMBL3942703 IC50 27.0 nM
Cc1c(-c2cccc(Cl)c2Cl)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3921389 IC50 31.6 nM
Cc1c(-c2ccc3ccccc3c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3964888 IC50 34.9 nM
O=C1CN(c2cn[nH]c(=O)c2Cl)CCN1Cc1ccccc1C(F)(F)F CHEMBL4530872 IC50 50.11 nM
Cn1c(=O)n(CCCO)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(-c3cccc(Cl)c3)sc21 CHEMBL3968651 IC50 55.0 nM
Cc1c(-c2cccc(OC(F)(F)F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3973104 IC50 82.2 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3ccc(F)cc3C3CC3)C2)=C1Cl CHEMBL5170160 IC50 111.0 nM
Cc1c(-c2ccc(F)c(F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3958022 IC50 112.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(Oc3cccc(Cl)c3)sc21 CHEMBL3946580 IC50 117.0 nM
Cc1nc2c(c(Oc3ccc(F)cc3C(F)(F)F)n1)CCN(C1=C(Cl)C(=O)NC1=O)C2 CHEMBL5187587 IC50 125.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(-c3cccc(Cl)c3)oc21 CHEMBL3905424 IC50 134.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(C(O)c3ccc(Cl)cc3)c(Oc3cccc(OC(F)(F)F)c3)sc21 CHEMBL3933741 IC50 194.0 nM
CC(C)c1ccccc1-c1cc2c(=O)n(CCCO)c(=O)n(C)c2cn1 CHEMBL4468311 IC50 195.0 nM
Cn1c(=O)n(CCCOC(=O)O)c(=O)c2c(Cc3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)ncc21 CHEMBL4566586 IC50 195.0 nM
CC(C)CCc1c(-c2ccc(Cl)cc2)ncc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL4450304 IC50 195.0 nM
CC(C)c1ccccc1-c1ncc2c(c1Cc1ccc(Cl)cc1)c(=O)n(CCCO)c(=O)n2C CHEMBL4439752 IC50 195.0 nM
CC(C)CCc1c(-c2ccccc2C(C)C)ncc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL4467574 IC50 195.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(Oc3cccc(Cl)c3)ncc21 CHEMBL4540858 IC50 195.0 nM
CC(C)CCc1c(-c2cccc(Cl)c2)ncc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL4565087 IC50 195.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccccc3)c(-c3cccc(OC(F)(F)F)c3)ncc21 CHEMBL4468755 IC50 195.0 nM
Cc1c(-c2cccc(Cl)c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3903109 IC50 226.0 nM
O=c1c(O)c(-c2ccccc2Br)oc2cc(O)cc(O)c12 CHEMBL4442055 IC50 280.0 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3ccc(F)cc3Cl)C2)=C1Cl CHEMBL5201353 IC50 280.0 nM
Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1 CHEMBL262766 IC50 300.0 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3ccc(Cl)cc3C(F)(F)F)C2)=C1Cl CHEMBL5197504 IC50 314.0 nM
CC(C)CCc1c(-c2cccc(OC(F)(F)F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3952019 IC50 340.0 nM
CC(C)CC(O)c1c(-c2cccc(OC(F)(F)F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL3905720 IC50 369.0 nM
Cc1cccc(C)c1CN1CCN(c2cn[nH]c(=O)c2Cl)CC1=O CHEMBL4452948 IC50 380.0 nM
Cc1c(-c2cccc(OC(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c2c(=O)n(CCCO)c(=O)n(C)c12 CHEMBL4565109 IC50 408.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c1cc(-c1cccc(Cl)c1)n2Cc1ccc(Cl)cc1 CHEMBL4444821 IC50 408.0 nM
Cn1c(-c2cccc(OC(F)(F)F)c2)cc2c1c(=O)n(CCCO)c(=O)n2C CHEMBL4576775 IC50 408.0 nM
Cc1c(-c2cccc(OC(F)(F)F)c2)n(C)c2c(=O)n(CCCO)c(=O)n(C)c12 CHEMBL4551497 IC50 408.0 nM
Cc1cn(Cc2ccc(Cl)cc2)c2c(=O)n(CCCO)c(=O)n(C)c12 CHEMBL4539201 IC50 408.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c1cc(-c1cccc(OC(F)(F)F)c1)n2Cc1ccc(Cl)cc1 CHEMBL4473077 IC50 408.0 nM
Cc1c(-c2cccc(OC(F)(F)F)c2)[nH]c2c(=O)n(CCCO)c(=O)n(C)c12 CHEMBL4435323 IC50 408.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c1c(-c1cccc(Cl)c1)cn2Cc1ccc(Cl)cc1 CHEMBL4551101 IC50 408.0 nM
O=c1c(O)c(-c2ccccc2)oc2cc(O)cc(O)c12 CHEMBL309490 IC50 450.0 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3ccccc3C(F)(F)F)C2)=C1Cl CHEMBL5203731 IC50 452.0 nM
CC(=O)OCC(=O)O[C@@H]1C[C@]2(C(C)C)O[C@@]1(C)[C@@H]1CC[C@@H](C)[C@H]1[C@@H]2OC(=O)/C=C/c1ccccc1 CHEMBL5177160 EC50 480.0 nM
Cc1ccccc1[C@H](C)N1CCN(c2cn[nH]c(=O)c2Cl)CC1=O CHEMBL4536108 IC50 490.0 nM
Cc1ccccc1CN1CCN(c2cn[nH]c(=O)c2Br)CC1=O CHEMBL4440201 IC50 500.0 nM
C[C@H]1CC[C@H](CN2CCN(c3cn[nH]c(=O)c3Cl)CC2=O)CC1 CHEMBL4517031 IC50 530.0 nM
O=C1CN(c2cn[nH]c(=O)c2Cl)CCN1Cc1ccccc1OC(F)(F)F CHEMBL4475970 IC50 530.0 nM
CCc1ccc2c(c1)nc(NCc1ccco1)n2Cc1ccccc1 CHEMBL5207902 IC50 540.0 nM
CC(C)c1ccc2c(c1)nc(NCc1ccco1)n2Cc1ccccc1 CHEMBL5201191 IC50 570.0 nM
Cn1c(=O)n(CCCO)c(=O)c2c(Cc3ccc(Cl)cc3)c(Oc3cccc(OC(F)(F)F)c3)sc21 CHEMBL3966562 IC50 584.0 nM
C#Cc1cc(F)ccc1Oc1ncnc2c1CCN(C1=C(Cl)C(=O)NC1=O)C2 CHEMBL5188705 IC50 629.0 nM
O=C1CN(c2cn[nH]c(=O)c2Cl)CCN1Cc1ccc(F)cc1C(F)(F)F CHEMBL4449727 IC50 650.0 nM
O=C1CN(c2cn[nH]c(=O)c2Cl)CCN1Cc1ccccc1Cl CHEMBL4563968 IC50 650.0 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3ccccc3Cl)C2)=C1Cl CHEMBL5175780 IC50 654.0 nM
Cc1ccccc1CN1CCN(c2cn[nH]c(=O)c2Cl)CC1=O CHEMBL4551777 IC50 660.0 nM
N#Cc1cc(F)ccc1Oc1ncnc2c1CCN(C1=C(Cl)C(=O)NC1=O)C2 CHEMBL5191955 IC50 664.0 nM
Cc1ccc2c(c1)nc(NCc1ccco1)n2Cc1ccccc1 CHEMBL5190035 IC50 670.0 nM
O=C1NC(=O)C(N2CCc3c(ncnc3Oc3c(F)cccc3C(F)(F)F)C2)=C1Cl CHEMBL5177892 IC50 776.0 nM
CCc1nc2c(c(Oc3ccc(F)cc3C(F)(F)F)n1)CCN(C1=C(Cl)C(=O)NC1=O)C2 CHEMBL5179669 IC50 798.0 nM
c1ccc(Cn2c(NCc3ccco3)nc3cc(C4CC4)ccc32)cc1 CHEMBL5169865 IC50 820.0 nM
O=C1NC(=O)C(N2CCc3ncn(Cc4ccccc4C(F)(F)F)c3C2)=C1Cl CHEMBL5198318 IC50 860.0 nM
CCc1ccc2c(c1)nc(NCc1ccco1)n2Cc1ccc(OC(F)(F)F)cc1 CHEMBL5203265 IC50 920.0 nM
O=C1NC(=O)C(N2CCc3c(cnn3Cc3ccccc3C(F)(F)F)C2)=C1Cl CHEMBL5181130 IC50 955.0 nM
CCc1ccc2c(c1)nc(NCc1ccco1)n2Cc1ccc(F)cc1 CHEMBL5209321 IC50 960.0 nM