Cc1ccc(Cn2c(N3CC[C@@H](F)[C@H](N)C3)nc3cc(F)c(F)cc32)nc1 CHEMBL4764496 IC50 0.1 nM
N[C@@H]1CN(c2nc3ccc(F)cc3n2Cc2ncc(F)cn2)CC[C@H]1F CHEMBL4741505 IC50 0.2 nM
N[C@@H]1CN(c2nc3cc(F)ccc3n2Cc2ccc(Cl)cn2)CCC1(F)F CHEMBL4752852 IC50 0.3 nM
COc1cc(F)c2nc(N3CC[C@@H](F)[C@H](N)C3)n(Cc3ncc(Cl)cn3)c2c1 CHEMBL4776935 IC50 0.4 nM
N[C@@H]1CN(c2nc3cc(F)ccc3n2Cc2ncc(F)cn2)CC[C@H]1F CHEMBL4753871 IC50 0.4 nM
N[C@@H]1CN(c2nc3ccc(F)cc3n2Cc2ccc(F)cn2)CC[C@H]1F CHEMBL4746182 IC50 0.4 nM
C[C@]12CCC(F)=C[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4129456 IC50 3.0 nM
CC1CCCN(C(=O)c2nc(Nc3cc4c(cc3F)OCO4)sc2Cl)C1C CHEMBL2418809 IC50 4.0 nM
N#Cc1ccc(O[C@@H]2c3ccccc3C[C@H]2N2CCC[C@@H](N)C2)c(Cl)c1 CHEMBL4129809 IC50 7.9 nM
N#Cc1ccc(O[C@@H]2[C@@H]3[C@H](C[C@H]2N2CCC[C@@H](N)C2)[C@@H]2CC(=O)[C@H]3C2)cc1 CHEMBL4129805 IC50 8.0 nM
C[C@]12CCC(=O)C[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4127600 IC50 11.0 nM
Cc1sc(Nc2ccc(Cl)cc2F)nc1C(=O)N1CCC[C@H](C)[C@@H]1C CHEMBL2418811 IC50 16.0 nM
CC1CCCN(C(=O)c2csc(Nc3ccc4c(c3)OCO4)n2)C1C CHEMBL2418807 IC50 16.0 nM
N#Cc1ccc(O[C@@H]2[C@@H]3CCC(=O)[C@@H]3C[C@H]2N2CCC[C@@H](N)C2)cc1 CHEMBL4126041 IC50 22.0 nM
Cc1sc(Nc2cc3c(cc2F)OCO3)nc1C(=O)N1CCCC(C)C1C CHEMBL2418808 IC50 25.0 nM
C[C@]12CCC(F)(F)C[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4128079 IC50 30.0 nM
Cc1sc(Nc2ccc3c(c2)OCO3)nc1C(=O)N1CCc2ccccc2C1C CHEMBL2418815 IC50 32.0 nM
CO/N=C1\CC[C@@]2(C)[C@@H](C1)C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4128782 IC50 33.0 nM
C[C@]12CCCC[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4127190 IC50 37.0 nM
C[C@]12CC[C@@H](O)C[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4125756 IC50 49.0 nM
Cc1sc(Nc2ccc(Cl)cc2F)nc1C(=O)N1CCCC(C)C1C CHEMBL2418810 IC50 50.0 nM
CO[C@@H]1CC[C@@]2(C)[C@@H](C1)C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4126989 IC50 52.0 nM
CC1c2ccccc2CCN1C(=O)c1csc(Nc2ccc3c(c2)OCO3)n1 CHEMBL2418814 IC50 63.0 nM
Cc1ccc(Nc2nc(C(=O)N3CCCC(C)C3C)cs2)cc1 CHEMBL2418806 IC50 80.0 nM
O=C(c1csc(Nc2ccc3c(c2)OCO3)n1)N1CCc2ccccc2C1 CHEMBL2418813 IC50 160.0 nM
CC1CCN(C(=O)c2csc(Nc3ccc4c(c3)OCO4)n2)CC1 CHEMBL2418823 IC50 160.0 nM
N#Cc1ccc(O[C@@H]2[C@@H]3CC(=O)[C@@H]3C[C@H]2N2CCC[C@@H](N)C2)cc1 CHEMBL4130214 IC50 160.0 nM
C=C[C@](C)(O)CC[C@H]1C(=C)C[C@H](OC(N)=O)[C@H]2C(C)(C)CCC[C@]12C CHEMBL4567792 IC50 170.0 nM
C[C@]12CC[C@H](C(F)F)C[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4129002 IC50 200.0 nM
CC1(O)CC[C@@]2(C)[C@H](C[C@@H](N3CCC[C@@H](N)C3)[C@@H]2Oc2ccc(C#N)cc2)C1 CHEMBL4126938 IC50 210.0 nM
C=C[C@@](C)(CC[C@H]1C(=C)C[C@H](OC(N)=O)[C@H]2C(C)(C)CCC[C@]12C)OC(C)=O CHEMBL4458930 IC50 250.0 nM
CN(C)C(=O)/C=C1\CC[C@@]2(C)[C@@H](C1)C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4126435 IC50 280.0 nM
C[C@@]12CCC(=O)C[C@@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4126528 IC50 390.0 nM
Cc1ccc(Nc2nc(C(=O)N3CCC(C)CC3)cs2)cc1 CHEMBL2418818 IC50 400.0 nM
CO[C@H]1CC[C@@]2(C)[C@@H](C1)C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4127992 IC50 440.0 nM
COc1ccc(Nc2nc(C(=O)N3CCc4ccccc4C3)cs2)cc1 CHEMBL1506485 IC50 500.0 nM
N#Cc1ccc(O[C@@H]2CCC[C@H]2N2CCC[C@@H](N)C2)cc1 CHEMBL4129133 IC50 500.0 nM
C[C@]12CC[C@H](O)C[C@H]1C[C@@H](N1CCC[C@@H](N)C1)[C@@H]2Oc1ccc(C#N)cc1 CHEMBL4129913 IC50 560.0 nM
Cc1ccc(Nc2nc(C(=O)N3CCCCC3C)cs2)cc1 CHEMBL2418824 IC50 630.0 nM
CC1CCN(C(=O)c2csc(Nc3ccc(Cl)cc3F)n2)CC1 CHEMBL2418822 IC50 630.0 nM
N#Cc1ccc(O[C@@H]2CCC[C@H]2N2CCC[C@@H](N)C2)c(Cl)c1 CHEMBL4125839 IC50 660.0 nM
COc1ccc(Nc2nc(C(=O)N3CCC(C)CC3)cs2)cc1 CHEMBL2418820 IC50 800.0 nM
CC1CCN(C(=O)c2csc(Nc3ccc(Cl)cc3)n2)CC1 CHEMBL2418819 IC50 800.0 nM