COc1ccc(/C=N/NC(=O)CCn2cc(Cl)c3c(C)cccc32)cc1OC CHEMBL3932326 IC50 1.3 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)cc2cccnc12 CHEMBL3926856 IC50 1.4 nM
COc1ccc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)cc1OC CHEMBL3921169 IC50 1.8 nM
COc1cc(F)c(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)cc1OC CHEMBL3984818 IC50 3.0 nM
Cc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)cc2cccnc12 CHEMBL3890861 IC50 5.0 nM
COc1ccc(/C=N/NC(=O)CCn2cc(C)c3c(OC)cccc32)cc1OC CHEMBL3920665 IC50 6.0 nM
Clc1cnc(CNc2cc3sncc3cc2Cl)s1 CHEMBL4863993 pEC50 7.943 nM
COc1ccc(/C=N/NC(=O)CCc2cn(C)c3c(C)cccc23)cc1OC CHEMBL3958181 IC50 9.0 nM
Cn1c(Cl)cnc1CNc1cc2sncc2cc1Cl CHEMBL4877000 pEC50 11.22 nM
COc1ccc(/C=N/NC(=O)CCn2ccc3c(C)cccc32)cc1OC CHEMBL3917255 IC50 12.0 nM
COc1ccc(/C=N/NC(=O)CCn2cc(C)c3ccccc32)cc1OC CHEMBL3952275 IC50 17.0 nM
Cc1cc2cnsc2cc1NCc1ncc(Cl)s1 CHEMBL4856061 pEC50 17.78 nM
Cc1cccc2c1c(C)cn2CCC(=O)N/N=C/c1ccc2c(c1)OCCCO2 CHEMBL3910957 IC50 24.0 nM
Clc1cnc(CNc2cc3cnsc3cc2Cl)s1 CHEMBL4869759 pEC50 24.55 nM
Fc1cc2cnsc2cc1NCc1ncc(Cl)s1 CHEMBL4855103 pEC50 28.84 nM
Cc1cn(CCC(=O)N/N=C/c2cc(C)c3ncccc3c2)c2ccccc12 CHEMBL3965696 IC50 30.0 nM
COc1ccc(/C=N/NC(=O)[C@@H]2C[C@H]2c2cccc(C(F)(F)F)c2)cc1OC CHEMBL3918456 IC50 37.0 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)cc(Cl)c1OC CHEMBL3949870 IC50 38.0 nM
Cc1cc2cnsc2cc1NCc1ncc(Cl)n1C CHEMBL4857667 pEC50 38.02 nM
Cc1cc2sncc2cc1NCc1ncc(Cl)s1 CHEMBL4860824 pEC50 38.9 nM
COc1ccc(/C=N/NC(=O)CSc2cccc(Cl)c2)cc1OC CHEMBL3954591 IC50 40.0 nM
Clc1cnc(CNc2ccc3cnsc3c2)s1 CHEMBL4854482 pEC50 43.65 nM
COc1cc(/C=N/NC(=O)[C@@H]2C[C@H]2c2cccc(Cl)c2)cc2cccnc12 CHEMBL3964050 IC50 45.0 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)ccc1OCc1ccncc1 CHEMBL3968083 IC50 46.0 nM
OC[C@@H]1Cc2cc(Cl)c(Cl)cc2[C@H](c2ccccc2)N1 CHEMBL5177026 pEC50 50.12 nM
COc1ccc(/C=N/NC(=O)CCc2cn(C)c3ccccc23)cc1OC CHEMBL3968112 IC50 51.0 nM
COc1ccc(/C=N/NC(=O)NCCc2ccc(Cl)cc2)cc1OC CHEMBL3981183 IC50 51.0 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)ccc1OCc1cccnc1 CHEMBL3914721 IC50 53.0 nM
COc1ccc(/C=N/NC(=O)C(C)Sc2cccc(Cl)c2)cc1OC CHEMBL3980338 IC50 55.0 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)ccc1OCc1cnccn1 CHEMBL3918736 IC50 60.0 nM
OC[C@@H]1Cc2cc(Cl)ccc2[C@H](c2cc(F)cc(Cl)c2)N1 CHEMBL5193084 pEC50 63.1 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)ccc1OCc1ccccn1 CHEMBL3974283 IC50 66.0 nM
N#Cc1ccc2c(c1)C[C@H](CO)N[C@@H]2c1cc(F)cc(Cl)c1 CHEMBL5192928 pEC50 79.43 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)ccc1OCc1ccccc1 CHEMBL3971765 IC50 80.0 nM
CN(Cc1ncc(Cl)n1C)c1ccc2cnsc2c1 CHEMBL4845759 pEC50 85.11 nM
Clc1cnc(CNc2ccc3sncc3c2)s1 CHEMBL4849726 pEC50 89.13 nM
COc1cc(/C=N/NC(=O)[C@@H]2C[C@H]2c2ccccc2)cc2cccnc12 CHEMBL3944989 IC50 90.0 nM
Fc1cc2sncc2cc1NCc1ncc(Cl)s1 CHEMBL4873593 pEC50 97.72 nM
OC[C@@H]1Cc2ccc(Cl)cc2[C@H](c2cc(F)cc(Cl)c2)N1 CHEMBL5194924 pEC50 100.0 nM
Cn1c(Cl)cnc1CNc1cc2sncc2cc1F CHEMBL4862183 pEC50 102.33 nM
COc1ccnc2ccc(/C=N/NC(=O)CCn3cc(C)c4ccccc43)cc12 CHEMBL3893648 IC50 120.0 nM
CN(Cc1ncc(Cl)n1C)c1ccc2sncc2c1 CHEMBL4869736 pEC50 158.49 nM
Cn1c(Cl)cnc1CN(CC1CC1)c1ccc2sncc2c1 CHEMBL4863223 pEC50 158.49 nM
Cc1cc(/C=N/NC(=O)CCc2cn(C)c3ccccc23)cc2cccnc12 CHEMBL3942291 IC50 160.0 nM
COc1ccc(/C=N/NC(=O)CCn2ccc3ccccc32)cc1OC CHEMBL3928377 IC50 170.0 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3c(C)cccc32)ccc1OCc1cccnn1 CHEMBL3965662 IC50 180.0 nM
Cc1cn(CCC(=O)N/N=C/c2ccc3c(c2)OCCCO3)c2ccccc12 CHEMBL3899989 IC50 180.0 nM
OC[C@@H]1Cc2ccc(Cl)cc2[C@H](c2cc(Cl)cc(Cl)c2)N1 CHEMBL5189636 pEC50 199.53 nM
OC[C@@H]1Cc2ccc(Cl)cc2[C@H](c2cc(F)cc(F)c2)N1 CHEMBL5186500 pEC50 199.53 nM
COc1ccc(/C=N/NC(=O)NCCc2ccccc2)cc1OC CHEMBL3951939 IC50 200.0 nM
Cc1cnc2ccc(/C=N/NC(=O)CCn3cc(C)c4ccccc43)cc2c1 CHEMBL3931655 IC50 210.0 nM
Cc1cc(/C=N/NC(=O)[C@H]2C[C@@H]2c2ccccc2)cc2cccnc12 CHEMBL3934816 IC50 240.0 nM
N#Cc1cc(F)cc([C@@H]2N[C@H](CO)Cc3cc(Cl)ccc32)c1 CHEMBL5188072 pEC50 251.19 nM
COc1ccc(/C=N/NC(=O)CCn2cc(C)c3c(CO)cccc32)cc1OC CHEMBL3935046 IC50 260.0 nM
Cn1c(Cl)cnc1CNc1ccc2cnsc2c1 CHEMBL4866122 pEC50 295.12 nM
CN(Cc1ncc(Cl)n1C)c1cc2sncc2cc1Cl CHEMBL4849376 pEC50 309.03 nM
OC[C@@H]1Cc2cc(Cl)c(F)cc2[C@H](c2ccccc2)N1 CHEMBL5181952 pEC50 316.23 nM
OC[C@@H]1Cc2ccc(Cl)cc2[C@H](c2cccc(F)c2)N1 CHEMBL5179994 pEC50 316.23 nM
Cn1c(Cl)cnc1CNc1ccc2sncc2c1 CHEMBL4876211 pEC50 331.13 nM
O=C(N/N=C/c1cc(Cl)c2ncccc2c1)[C@@H]1C[C@H]1c1ccccc1 CHEMBL3966655 IC50 340.0 nM
Cc1cn(CCC(=O)N/N=C/c2ccc3ncccc3c2)c2ccccc12 CHEMBL3971296 IC50 340.0 nM
Cc1ccnc2ccc(/C=N/NC(=O)CCn3cc(C)c4ccccc43)cc12 CHEMBL3928916 IC50 370.0 nM
COc1cccc([C@@H]2C[C@H]2C(=O)N/N=C/c2cc(C)c3ncccc3c2)n1 CHEMBL3930285 IC50 410.0 nM
Cc1cn(CCC(=O)N/N=C/c2ccc3nnccc3n2)c2ccccc12 CHEMBL3944040 IC50 430.0 nM
CN(Cc1ncc(Cl)s1)c1ccc2sncc2c1 CHEMBL4863555 pEC50 446.68 nM
Cn1c(Br)cnc1CNc1ccc2sncc2c1 CHEMBL4855887 pEC50 457.09 nM
CCN(Cc1ncc(Cl)n1C)c1ccc2sncc2c1 CHEMBL4849797 pEC50 467.74 nM
Clc1cnc(CNc2cc3cnsc3cn2)s1 CHEMBL4858854 pEC50 467.74 nM
FC(F)(F)c1cnc(CNc2ccc3sncc3c2)s1 CHEMBL4874619 pEC50 489.78 nM
COc1cc(/C=N/NC(=O)CCn2cc(C)c3ccccc32)ccc1OCCCO CHEMBL3978819 IC50 500.0 nM
OC[C@@H]1Cc2cc(Cl)ccc2[C@H](c2ccccc2)N1 CHEMBL5209164 pEC50 501.19 nM
OC[C@@H]1Cc2ccc(Cl)cc2[C@H](c2cccc(Cl)c2)N1 CHEMBL5202815 pEC50 501.19 nM
Cc1cc(/C=N/NC(=O)[C@@H]2C[C@H]2c2ccc(F)cc2)cc2cccnc12 CHEMBL3955382 IC50 510.0 nM
O=C(N/N=C/c1cc(F)c2ncccc2c1)[C@@H]1C[C@H]1c1ccccc1 CHEMBL3969447 IC50 550.0 nM
Cc1cnc(CNc2ccc3sncc3c2)s1 CHEMBL4866780 pEC50 575.44 nM
COc1ccc(/C=N/NC(=O)C2CC2c2ccccc2)cc1OC CHEMBL5183139 IC50 600.0 nM
COc1ccc(/C=N/NC(=O)Cc2cccc3ccccc23)cc1OC CHEMBL5196998 IC50 600.0 nM
COc1ccc(/C=N/NC(=O)[C@@H]2C[C@H]2c2ccc3ccccc3n2)cc1OC CHEMBL3982510 IC50 610.0 nM
C=CCNC(=S)/N=c1/sc2ccccc2n1C CHEMBL5209032 pEC50 630.96 nM
O=C(N/N=C/c1cc(Cl)c2ncccc2c1)[C@@H]1C[C@H]1c1cccc(Cl)c1 CHEMBL3947573 IC50 650.0 nM
COc1ccc(/C=N/NC(=O)CSc2ccccc2)cc1OC CHEMBL3209049 IC50 660.0 nM
COc1ccc(/C=N/NC(=O)CCn2cc(C)c3cccnc32)cc1OC CHEMBL3952534 IC50 680.0 nM
Cc1cn(CCC(=O)N/N=C/c2ccc3c(c2)OCCN3C)c2ccccc12 CHEMBL3968552 IC50 750.0 nM
OC[C@@H]1Cc2ccc(Cl)cc2[C@H](c2ccccc2)N1 CHEMBL5175850 pEC50 794.33 nM
Cc1cc(/C=N/NC(=O)[C@@H]2C[C@H]2c2cccc(Cl)c2)cc2cccnc12 CHEMBL3950228 IC50 800.0 nM
COc1ccc(/C=N/NC(=O)CCc2cnc3ccccc3c2)cc1OC CHEMBL3913484 IC50 810.0 nM
Cc1cc(/C=N/NC(=O)CSc2cccc(Cl)c2)cc2cccnc12 CHEMBL3934275 IC50 830.0 nM
Clc1cnc(COc2ccc3sncc3c2)s1 CHEMBL4867011 pEC50 831.76 nM
Fc1c(NCc2ncc(Cl)s2)ccc2sncc12 CHEMBL4872165 pEC50 933.25 nM
Cc1cc([C@@H]2N[C@H](CO)Cc3ccc(Cl)cc32)ccc1Cl CHEMBL5184410 pEC50 1000.0 nM