CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385223 Ki 0.001 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Oc1cc(I)c(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL595262 EC50 0.0047 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)[C@@H](C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177429 Ki 0.01 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Cc1ccc(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL17976 EC50 0.019 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3cnccc23)CC1 CHEMBL3393837 Ki 0.02 nM
CCCCOc1nc(C(F)(F)Cl)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407762 Ki 0.02 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177428 Ki 0.02 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1SC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627950 Ki 0.03 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)cc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627723 Ki 0.03 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1OC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407765 Ki 0.04 nM
C[C@H](C(=O)NCc1cc(C(C)(C)C)nn1-c1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689037 Ki 0.04 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442912 Ki 0.05 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1=C[C@H](C)CCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314406 Ki 0.1 nM
CCC1CC=C(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3314407 Ki 0.1 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1C1=CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314409 Ki 0.1 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1C1=CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314411 Ki 0.1 nM
Cc1cccc(C(C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)c2ccc(NS(C)(=O)=O)c(F)c2)c1 CHEMBL3427109 Ki 0.1 nM
COc1cc(CC(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc(Br)c1O CHEMBL3681230 Ki 0.1 nM
C[C@H](C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689046 Ki 0.1 nM
CCC1CCN(c2nc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL4104073 Ki 0.1 nM
C[C@H](C(=O)NCc1cc(C(C)(C)C)nn1-c1ccc(F)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4215829 Ki 0.1 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cc(Cl)c(N)c(Cl)c2)CC1 CHEMBL4242293 Ki 0.1 nM
CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 CHEMBL228451 IC50 0.11 nM
COc1cc(CC(=O)OCC2=C[C@H]3[C@@H]4C(C)(C)[C@]4(OC(C)=O)[C@H](OC(=O)Cc4ccccc4)[C@@H](C)[C@]3(O)[C@@H]3C=C(C)C(=O)[C@@]3(O)C2)ccc1O CHEMBL104647 Ki 0.12 nM
C=C(C(=O)OCC1=C[C@H]2[C@H]3O[C@@]4(Cc5ccccc5)O[C@@]2([C@H](C)C[C@]3(C(=C)C)O4)[C@@H]2C=C(C)C(=O)[C@@]2(O)C1)c1ccc(O)c(OC)c1 CHEMBL594016 EC50 0.15 nM
CC(C)(C)c1ccc(NC(=O)N2CCN(c3ncccc3Cl)CC2)cc1 CHEMBL441472 IC50 0.15 nM
C[C@H](NCc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)cc1)C(F)(F)F CHEMBL1761696 pIC50 0.1585 nM
FC(F)(F)c1ccc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)cnc23)nc1 CHEMBL1214342 IC50 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccc(F)c(F)c2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178059 Ki 0.2 nM
Cc1ccc(CC2CCN(c3nc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)cc1 CHEMBL2177441 Ki 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177440 Ki 0.2 nM
CCCN(CCC)c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178063 Ki 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317476 Ki 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1Cl)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314377 Ki 0.2 nM
CCC1CCC(c2nc(C(F)(F)F)ccc2CNC(=O)[C@@H](C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3314393 Ki 0.2 nM
CC1CC=C(c2nc(C(F)(F)F)ccc2CNC(=O)[C@@H](C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3314404 Ki 0.2 nM
CC1C=C(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CCC1 CHEMBL3314405 Ki 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1=CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314408 Ki 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1=CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314410 Ki 0.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314389 Ki 0.2 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(F)c(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL4125690 Ki 0.2 nM
FC(F)(F)c1ccc(Nc2ncnc3nc(-c4ncccc4C(F)(F)F)cnc23)cc1 CHEMBL1092853 IC50 0.21 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3[nH]c(=O)ccc23)CC1 CHEMBL4781687 IC50 0.27 nM
CC(C)COc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385408 Ki 0.29 nM
CC(C)(C)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1 CHEMBL323134 Ki 0.3 nM
FC(F)(F)c1ccc(-c2cc(Nc3ccc4cccnc4c3)ncn2)cc1 CHEMBL226723 IC50 0.3 nM
CC(C)OCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL457188 IC50 0.3 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177435 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177432 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CC=CCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177425 Ki 0.3 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177424 Ki 0.3 nM
CC1CCCN1c1nc(C(F)(F)F)ccc1CNC(=O)[C@@H](C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178068 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCCC1CCCCN1C(=O)OC(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385220 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCC1CCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385248 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC[C@@H]1C[C@H]1C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385246 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCC(C(F)(F)F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385418 Ki 0.3 nM
CCCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385423 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1cccs1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317484 Ki 0.3 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1C1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314390 Ki 0.3 nM
CCC1CCC(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3314392 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314394 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1[C@H]1CC[C@H](C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314396 Ki 0.3 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1C1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314398 Ki 0.3 nM
CC1CC=C(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3314403 Ki 0.3 nM
CC1CCN(c2nc(C(F)(F)Cl)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3407753 Ki 0.3 nM
CCCN(CCC)c1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629486 Ki 0.3 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cc(Br)c(O)c(Br)c2)CC1 CHEMBL3681232 Ki 0.3 nM
CC(C(=O)NCc1cc(C(C)(C)C)nn1-c1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689036 Ki 0.3 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689041 Ki 0.3 nM
C[C@H](C(=O)NCc1cc(C(F)(F)F)nn1-c1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689043 Ki 0.3 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689044 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1-c1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4078240 Ki 0.3 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1N1CCC(Cc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4105672 Ki 0.3 nM
COc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc(F)c1NS(C)(=O)=O CHEMBL4129132 Ki 0.3 nM
CC(C)(C)c1ccc2c(c1)CC[C@H]2NC(=O)Nc1cccc2[nH]ncc12 CHEMBL398338 Ki 0.3 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)n(-c2cccc(C(F)(F)F)c2)n1 CHEMBL4782906 Ki 0.3 nM
CCCCCC[C@H](C/C=C\CCCCCCCC(=O)NCc1ccc(O)c(OC)c1)OC(C)=O CHEMBL124602 Log EC50 0.3981 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)Cc4cc(I)c(O)c(OC)c4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL408581 IC50 0.4 nM
Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2[nH]c1=O CHEMBL375681 IC50 0.4 nM
CC1CN(Cc2nc(Nc3ccc(C(F)(F)F)cc3)c3ccc(-c4ncccc4C(F)(F)F)cc3n2)CC(C)O1 CHEMBL456162 IC50 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2cc(F)cc(F)c2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177402 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385249 Ki 0.4 nM
CCCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)[C@@H](C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385426 Ki 0.4 nM
Cc1cc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)ccc1F CHEMBL3317477 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319108 Ki 0.4 nM
CC1CCC(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3314391 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314397 Ki 0.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3ccncc23)CC1 CHEMBL3393836 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(Cc2cccc(F)c2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629498 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(Cc2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629497 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(C(F)(F)F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629494 Ki 0.4 nM
CCCCCc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629227 Ki 0.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(C(F)(F)F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177405 Ki 0.4 nM
COc1cc(C(C)C(=O)NCc2cc(C(F)(F)F)nn2-c2cccc(Cl)c2)ccc1NS(C)(=O)=O CHEMBL3689048 Ki 0.4 nM
C[C@@H]1CN(c2ncc([C@@H](O)CO)cc2F)CCN1C(=O)Nc1nc2ccc(Cl)cc2s1 CHEMBL4111432 IC50 0.4 nM
Cc1ccc2nc(NC(=O)N3CCN(c4ncc([C@@H](O)CO)cc4F)C[C@H]3C)sc2c1 CHEMBL4113986 IC50 0.4 nM
Cn1ncc2c(NC(=O)NCc3cc(C(C)(C)C)nn3-c3cccc(Cl)c3)cccc21 CHEMBL4752231 Ki 0.4 nM
O=C(/C=C/c1ccc(C(F)(F)F)nc1N1CCCCC1)Nc1ccc2cccnc2c1 CHEMBL190874 IC50 0.42 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177423 Ki 0.43 nM
CN(C)C1(Cc2ccccc2)CCN(c2cc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3ccc(O)cc23)CC1 CHEMBL4471708 Ki 0.46 nM
CCCN(CCC)c1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5406113 IC50 0.46 nM
C[C@H](C(=O)NCc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2042399 Ki 0.49 nM
FC(F)(F)c1ccc(Nc2nc(COCc3ccccc3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL456778 IC50 0.5 nM
Cc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL526827 IC50 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177404 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385224 Ki 0.5 nM
CCCCC(CCC)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385413 Ki 0.5 nM
CCCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385425 Ki 0.5 nM
CC1CCC(Sc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2442916 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319115 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319112 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1N1CCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407760 Ki 0.5 nM
CC(C)CCOc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627940 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1SCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627953 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627951 Ki 0.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1OCc1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627944 Ki 0.5 nM
CC(C(=O)NCc1cc(C(C)(C)C)nn1-c1ccc(F)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689038 Ki 0.5 nM
Cc1nnc(-c2cnc(C3=CCN(C(=O)Nc4ccc(C(C)(C)C)cc4)CC3)c(Cl)c2)o1 CHEMBL3910069 IC50 0.5 nM
CCCCCCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4102090 Ki 0.5 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)n(-c2ccc(F)c(F)c2)n1 CHEMBL4745407 Ki 0.5 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)n(-c2ccc(F)c(Cl)c2)n1 CHEMBL4792344 Ki 0.5 nM
COc1cc(CNC(=O)/C=C(\C)CC/C=C(\C)CCC=C(C)C)ccc1O CHEMBL121808 Log EC50 0.5012 nM
CCCCCCCC/C=C\CCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL76903 Log EC50 0.5012 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL123254 Log EC50 0.5012 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1Cl CHEMBL1669532 pIC50 0.5012 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccccc1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770682 Ki 0.54 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3C)CC1 CHEMBL4786158 Ki 0.57 nM
OC1CCc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 CHEMBL404165 IC50 0.58 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2OCC(=O)N3)CC1 CHEMBL4095861 Kd 0.589 nM
[3H]CC1([3H])CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2OCC(=O)N3)CC1 CHEMBL4077829 Kd 0.59 nM
CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)cccc2s1 CHEMBL229430 IC50 0.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177434 Ki 0.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178067 Ki 0.6 nM
CCCCN(CCCC)c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178064 Ki 0.6 nM
Cc1ccc(CCc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3317497 Ki 0.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1CCC(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314383 Ki 0.6 nM
CC(C)COc1nc(C(F)(F)Cl)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407764 Ki 0.6 nM
CCCN(CCC)c1nc(C(F)(F)Cl)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407758 Ki 0.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1C1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629228 Ki 0.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1-c1ccc(F)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629233 Ki 0.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1OC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627941 Ki 0.6 nM
C[C@@H]1CN(c2ncc([C@@H](O)CO)cc2F)CCN1C(=O)Nc1nc2ccc(F)cc2s1 CHEMBL4109185 IC50 0.6 nM
CC(C)CCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4093420 Ki 0.6 nM
CC(C)COc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4070760 Ki 0.6 nM
Cc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)ccc1NS(C)(=O)=O CHEMBL4127673 Ki 0.6 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)n(-c2cccc(Cl)c2)n1 CHEMBL4753881 Ki 0.6 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1ccc(F)c(Cl)c1)Nc1cccc2[nH]ncc12 CHEMBL4763915 Ki 0.6 nM
Cn1ncc2c(NC(=O)NCc3cc(C(C)(C)C)nn3-c3cccc(C(F)(F)F)c3)cccc21 CHEMBL4756342 Ki 0.6 nM
Cn1ncc2c(NC(=O)NCc3cc(C(C)(C)C)nn3-c3ccc(F)c(Cl)c3)cccc21 CHEMBL4763969 Ki 0.6 nM
FC(F)(F)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)cnc23)cc1 CHEMBL1089824 IC50 0.63 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(C(F)(F)F)c(F)c2)c1Cl CHEMBL1807875 pIC50 0.631 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(Cl)c(F)c2)c1Cl CHEMBL1807877 pIC50 0.631 nM
Cc1cccc(-n2nc(C(F)(F)F)cc2CNC(=O)Nc2cccc3[nH]c(=O)ccc23)c1 CHEMBL4787931 IC50 0.64 nM
Oc1ccc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2c1 CHEMBL255420 IC50 0.65 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)C(OC(C)=O)c1ccc(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL594649 EC50 0.65 nM
CN(C)C1(Cc2ccccc2)CCN(c2cc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3cnccc23)CC1 CHEMBL4553702 Ki 0.67 nM
CCCCCCCc1cn(Cc2cc(OC)c(O)cc2I)nn1 CHEMBL4749288 Ki 0.69 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2179146 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177419 Ki 0.7 nM
CC1CC(C)CN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C1 CHEMBL2177433 Ki 0.7 nM
COc1cc(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc(OC)c1 CHEMBL2385238 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385250 Ki 0.7 nM
CC(C)CC(CC(C)C)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385414 Ki 0.7 nM
CCCC(CCC)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385412 Ki 0.7 nM
CCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385424 Ki 0.7 nM
CC(C)CCSc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442897 Ki 0.7 nM
CCCCSc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442894 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319111 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1/C=C/C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314387 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1/C=C/C1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314388 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1=CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314402 Ki 0.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3ncccc23)CC1 CHEMBL3393838 Ki 0.7 nM
Cc1ccc(N2CCN(c3cc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)cc1 CHEMBL3629501 Ki 0.7 nM
CCC1CCN(c2cc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3629492 Ki 0.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1OC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627942 Ki 0.7 nM
CCCCCOc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627937 Ki 0.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cc(Br)c(N)c(Br)c2)CC1 CHEMBL3681231 Ki 0.7 nM
CC1CCN(c2cc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL4070600 Ki 0.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(F)c(NS(C)(=O)=O)c(Br)c2)CC1 CHEMBL4127070 Ki 0.7 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Cc1cc(OC)c(O)cc1I)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL18441 Ki 0.71 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770091 Ki 0.71 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCCCC1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4789232 IC50 0.75 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3769821 Ki 0.76 nM
O=C(NCc1ccc(Cl)c(C(F)(F)F)c1)Nc1cccc2cnccc12 CHEMBL102486 Ki 0.8 nM
CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3N(S(C)(=O)=O)S(C)(=O)=O)cc2)cc1 CHEMBL214989 IC50 0.8 nM
O=C(Nc1cccc2cnccc12)NC1CCc2cc(F)ccc2C1CC1CC1 CHEMBL248561 Ki 0.8 nM
FC(F)(F)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL214796 IC50 0.8 nM
NC(=O)c1cnc(-c2cnc3c(Nc4ccc(C(F)(F)F)cn4)ccnc3n2)c(C(F)(F)F)c1 CHEMBL1214402 IC50 0.8 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177418 Ki 0.8 nM
CC1CCCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C1 CHEMBL2177427 Ki 0.8 nM
CCCCN(C)c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178065 Ki 0.8 nM
COc1cccc(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c1 CHEMBL2385235 Ki 0.8 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1cccc(F)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385233 Ki 0.8 nM
CC(C)CCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385409 Ki 0.8 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C#Cc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317496 Ki 0.8 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1C1CC2CCC1C2)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314401 Ki 0.8 nM
CCCCCCOc1nc(C(F)(F)Cl)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407763 Ki 0.8 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1N1CCN(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407761 Ki 0.8 nM
COc1ccc(-c2cc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3629229 Ki 0.8 nM
CC(C)COc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627939 Ki 0.8 nM
CCCCCCOc1cc(C(C)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627938 Ki 0.8 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3689053 Ki 0.8 nM
CC(C)(C)c1ccc(NC(=O)N2CCN(c3ncc([C@H](O)CO)cc3Cl)CC2)cc1 CHEMBL4110774 IC50 0.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1N1CCN(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4096979 Ki 0.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1OCc1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4104241 Ki 0.8 nM
CC(C)CCOc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4091637 Ki 0.8 nM
CCCCCOc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4061052 Ki 0.8 nM
COc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)ccc1NS(C)(=O)=O CHEMBL4129439 Ki 0.8 nM
O=C(NCc1ccc(C(F)(F)F)nc1OCC1CCC1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5426914 IC50 0.81 nM
FC(F)(F)c1ccc(Nc2ncnc3nc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL1092852 IC50 0.83 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3ccc(=O)[nH]c3c2)CC1 CHEMBL4783554 Ki 0.83 nM
FC(F)(F)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)nc1 CHEMBL456571 IC50 0.85 nM
CC(C)c1cccc(-n2nc(C(F)(F)F)cc2CNC(=O)Nc2cccc3[nH]c(=O)ccc23)c1 CHEMBL4783757 IC50 0.88 nM
CCOCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL498666 IC50 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(C)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178066 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385241 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385416 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCCC(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385410 Ki 0.9 nM
CCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385422 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442911 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(Cl)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317478 Ki 0.9 nM
CC(C)CCCc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314382 Ki 0.9 nM
CCC/C=C/c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314385 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1OCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407950 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1OC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407949 Ki 0.9 nM
CC1CCN(c2nc(C3CC3)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3407754 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629495 Ki 0.9 nM
CC1CCN(c2cc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3629491 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1SCc1ccccc1Cl)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629221 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1OCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627943 Ki 0.9 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(Br)c(N)c(Br)c2)CC1 CHEMBL3681229 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccc(Cl)cc1)S(=O)(=O)c1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770670 Ki 0.9 nM
CC(C)(C)c1ccc(NC(=O)N2CC=C(c3ncc([C@H](O)CO)cc3F)CC2)cc1 CHEMBL4108193 IC50 0.9 nM
CCCCOc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4089226 Ki 0.9 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1N1CCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4067830 Ki 0.9 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)Nc1cccc2[nH]ncc12 CHEMBL4752959 Ki 0.9 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCCC1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4784134 IC50 0.94 nM
CN(C)C1(Cc2ccccc2)CCN(c2cc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2CC(O)CC3)CC1 CHEMBL4438643 Ki 0.95 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)C(C)c1ccc(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL594895 EC50 0.98 nM
COc1cc(CNC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)ccc1O CHEMBL3099608 EC50 0.99 nM
O=C(NCCc1ccc(Cl)c(Cl)c1)Nc1cccc2ccc(O)cc12 CHEMBL151298 Ki 1.0 nM
O=C(NCc1ccc(OC(F)(F)F)cc1)Nc1cccc2ccc(O)cc12 CHEMBL147068 Ki 1.0 nM
O=C(NCc1ccc(C(F)(F)F)cc1)Nc1cccc2ccc(O)cc12 CHEMBL148920 Ki 1.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2cc(F)ccc2C1Cc1ccc(C(F)(F)F)cc1 CHEMBL250594 Ki 1.0 nM
COc1ccc2c(c1)CCC(NC(=O)Nc1cccc3cnccc13)C2Cc1ccc(Br)cc1 CHEMBL250593 Ki 1.0 nM
O=S(=O)(c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1)N1CCCC1 CHEMBL511391 IC50 1.0 nM
OCc1cc(Cl)c(Nc2nc3c(Nc4ccc(C(F)(F)F)cc4)ncnc3s2)c(Cl)c1 CHEMBL516769 IC50 1.0 nM
CC(C)OCc1nc(Nc2ccc(C(F)(F)F)nc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL513942 IC50 1.0 nM
C[C@@H]1CN(Cc2nc(Nc3ccc(C(F)(F)F)cn3)c3ccc(-c4ncccc4C(F)(F)F)cc3n2)C[C@H](C)O1 CHEMBL457003 IC50 1.0 nM
CC(C)CNCc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)cc1 CHEMBL1761693 pIC50 1.0 nM
CC(C)(C)c1ccc(NC(=O)N2CCc3c([nH]c4ccc(O)cc34)C2)cc1 CHEMBL2312050 IC50 1.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1cc(F)cc(F)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385236 Ki 1.0 nM
CC1CCC(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2385251 Ki 1.0 nM
CC/C=C\COc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385255 Ki 1.0 nM
CCC1CCC(Sc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2442918 Ki 1.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1cc2ccccc2s1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317492 Ki 1.0 nM
COc1ccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3319113 Ki 1.0 nM
CCCCCc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3313936 Ki 1.0 nM
CC1CC(C)CN(c2nc(C(F)(F)Cl)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C1 CHEMBL3407759 Ki 1.0 nM
CC1CCN(c2nc(C(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3407752 Ki 1.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1-c1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629232 Ki 1.0 nM
CCCCOc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627936 Ki 1.0 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(N)(=O)=O)cc2)CC1 CHEMBL3694612 Ki 1.0 nM
Cc1ccc(CNC(=O)Nc2ccc(CNS(N)(=O)=O)c(F)c2)c(N2CCC(C)CC2)n1 CHEMBL3694614 Ki 1.0 nM
COC1CN(c2ncc(C[C@@H](O)CO)cc2Cl)CCN1C(=O)Nc1nc2ccc(F)cc2s1 CHEMBL3671846 IC50 1.0 nM
CN1C(=O)NCc2c(NC(=O)N[C@@H]3C[C@](C)(C(F)(F)F)Oc4ccccc43)cccc21 CHEMBL3682255 IC50 1.0 nM
Cc1cc(NC(=O)N2CC=C(c3ncc(-c4nnc(CO)o4)cc3C)CC2)ccc1C(F)(F)F CHEMBL3935231 IC50 1.0 nM
CCCCN(C)c1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4083611 Ki 1.0 nM
Cn1ncc2c(NC(=O)NCc3cc(C(C)(C)C)nn3-c3ccc(F)c(F)c3)cccc21 CHEMBL4790987 Ki 1.0 nM
COc1cc(CNC(=O)CCCc2ccc(-c3ccccc3)s2)ccc1O CHEMBL5428602 IC50 1.0 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccccc2)CC1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5409442 IC50 1.02 nM
O=C(NCc1ccc(C(F)(F)F)nc1OCC1CCCC1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5412992 IC50 1.08 nM
CC(C)(C)c1ccc(/C=C/C(=O)Nc2ccc3cccnc3c2)cc1 CHEMBL195115 IC50 1.1 nM
OC1CCc2cc(F)cc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 CHEMBL258054 IC50 1.1 nM
OC1CCc2ccc(Cl)c(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 CHEMBL258265 IC50 1.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2179150 Ki 1.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCC1CC1(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385247 Ki 1.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCC1CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385082 Ki 1.1 nM
CCC(CC)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385411 Ki 1.1 nM
CC(C(=O)NCc1ccc(C2CC2)nc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407757 Ki 1.1 nM
Cc1ccc(C(C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3425527 Ki 1.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1-c1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629230 Ki 1.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1SCc1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627954 Ki 1.1 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(Br)c(O)c(Br)c2)CC1 CHEMBL3681228 Ki 1.1 nM
CC(C)(C)c1ccc(NC(=O)N2CC=C(c3ncc([C@H](O)CO)cc3Cl)CC2)cc1 CHEMBL4112504 IC50 1.1 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4089039 Ki 1.1 nM
O=C(NCc1ccc(C(F)(F)F)nc1OCc1ccccc1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5430115 IC50 1.14 nM
CCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5403769 IC50 1.15 nM
CC(C)COc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5419861 IC50 1.16 nM
CCCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5434483 IC50 1.18 nM
CC(C)(C)c1ccc(/C=C/C(=O)Nc2cccc3cnccc23)cc1 CHEMBL105046 Ki 1.2 nM
CCN(CC)Cc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL457842 IC50 1.2 nM
O=C(/C=C/c1ccc(C(F)(F)F)nc1N1CCOCC1)Nc1ccc2cccnc2c1 CHEMBL191247 Ki 1.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442910 Ki 1.2 nM
CCCCN(C)c1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629361 Ki 1.2 nM
CC(C(=O)NCc1cc(C(C)(C)C)nn1-c1cccc(Cl)c1)c1cc(F)c(NS(C)(=O)=O)c(F)c1 CHEMBL3689049 Ki 1.2 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1N1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4095354 Ki 1.2 nM
CCCCN(C)c1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4097698 Ki 1.2 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)cc2)CC1 CHEMBL4129041 Ki 1.2 nM
O=C(NCc1ccc(C(F)(F)F)nc1OCc1ccccc1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4785229 IC50 1.2 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@@](Cc5ccccc5)(O[C@@H]1[C@H]3C=C(COC(=O)Cc1ccc(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL4060041 Kd 1.23 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCCCC1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5400968 IC50 1.23 nM
CCCCCCCC[C@@H]1C[C@@H]1CCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL124002 Log EC50 1.259 nM
CCCCCC/C=C/C#CCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL122864 Log EC50 1.259 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1CNCC1CCC1 CHEMBL1761695 pIC50 1.259 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(F)c1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4779695 IC50 1.28 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccc(Cl)cc1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3769673 Ki 1.29 nM
CC(C)(C)c1ccc(CCNC(=O)Nc2cccc3cnccc23)cc1 CHEMBL419351 Ki 1.3 nM
O=C(NCc1ccc(OC(F)(F)F)cc1)Nc1cccc2cnccc12 CHEMBL101751 Ki 1.3 nM
OC1CCc2cccc(Nc3nc(-c4ccc(F)cc4)c(-c4ccc(C(F)(F)F)cc4)o3)c2C1 CHEMBL1173756 IC50 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCOCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177400 Ki 1.3 nM
CCOC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177409 Ki 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCN(C(=O)OC(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385244 Ki 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385417 Ki 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1cccc(F)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319109 Ki 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1[C@H]1CC[C@@H](C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314395 Ki 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407756 Ki 1.3 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(c2ccccc2)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3427101 Ki 1.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629493 Ki 1.3 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(C(F)(F)F)c1)Nc1cccc2[nH]ncc12 CHEMBL4778103 Ki 1.3 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)n(-c2cccc(F)c2)n1 CHEMBL4798584 Ki 1.3 nM
CCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5427113 IC50 1.3 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)CC1 CHEMBL5408353 IC50 1.31 nM
COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)ccc1O CHEMBL392584 EC50 1.34 nM
CC(C)c1cccc(-n2nc(C(F)(F)F)cc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)c1 CHEMBL5413293 IC50 1.34 nM
CC(C)c1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3[nH]c(=O)ccc23)c1 CHEMBL4784658 IC50 1.35 nM
COCCn1c(=O)ccc2c(NC(=O)NCc3ccc(C(F)(F)F)nc3N3CCC(C)CC3)cccc21 CHEMBL5426292 IC50 1.35 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Nc1cccc2cnccc12 CHEMBL320906 Ki 1.4 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34OC(Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Cc1ccc(O)c(OC)c1I)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL18246 Ki 1.4 nM
OC1CCc2c(Cl)ccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 CHEMBL258056 IC50 1.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ccccn2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2179153 Ki 1.4 nM
COCC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177410 Ki 1.4 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1N1CC[C@@H](OCc2ccccc2)C1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178072 Ki 1.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385415 Ki 1.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1CCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317494 Ki 1.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccoc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317487 Ki 1.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(Cc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629496 Ki 1.4 nM
CC(C)CCSc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627948 Ki 1.4 nM
CCCCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4064110 Ki 1.4 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3cccc(C(F)(F)F)c3)cccc21 CHEMBL4740674 Ki 1.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1C[C@@H](C)O[C@@H](C)C1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177401 Ki 1.43 nM
CC1CCC(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3[nH]c(=O)ccc23)CC1 CHEMBL4790268 IC50 1.44 nM
O=C(NCc1ccc(C(F)(F)F)nc1-c1ccc(F)cc1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5414267 IC50 1.45 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Cc1cc(OC)c(OC(C)=O)cc1I)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL18058 Ki 1.46 nM
O=C(NCc1ccc(C(F)(F)F)nc1OCC1CCC1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4783214 IC50 1.49 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)/C=C/c4ccc(O)c(OC)c4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL234520 EC50 1.5 nM
COCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL497650 IC50 1.5 nM
CCC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177431 Ki 1.5 nM
Cc1ccc(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL2385225 Ki 1.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCCCOc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385406 Ki 1.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CCC(F)(F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314399 Ki 1.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CC2CCC1C2)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314400 Ki 1.5 nM
CCCCCCSc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4059664 Ki 1.5 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1OC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4076446 Ki 1.5 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1ccc(F)c(Cl)c1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5394003 IC50 1.51 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770984 Ki 1.56 nM
COc1ccc(CNC(=O)CCCC/C=C/CCCCCCCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O CHEMBL333489 Log EC50 1.585 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccccc2)CC1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4776559 IC50 1.59 nM
C/C=C\COc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385254 Ki 1.6 nM
CCCCCCc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314381 Ki 1.6 nM
CCC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3427096 Ki 1.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629489 Ki 1.6 nM
COc1ccc(N2CCN(c3cc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)cc1 CHEMBL3627933 Ki 1.6 nM
COc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc(OC)c1NS(C)(=O)=O CHEMBL4125837 Ki 1.6 nM
O=C(Nc1ccc2cn[nH]c2c1)N1CCN(c2ccc(Cl)cn2)CC1 CHEMBL5173171 EC50 1.62 nM
FC(F)(F)c1ccc(Nc2ccnc3cc(-c4ncccc4C(F)(F)F)ccc23)nc1 CHEMBL1093132 IC50 1.65 nM
COc1ccc(CN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL3770864 Ki 1.65 nM
CN(C)C1(Cc2ccccc2)CCN(c2cc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3[nH]c(=O)ccc23)CC1 CHEMBL4562769 Ki 1.67 nM
CCOC(=O)c1cccc(NC(=O)Nc2cccc3ccc(O)cc23)c1 CHEMBL1779676 IC50 1.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CC=C(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177437 Ki 1.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629488 Ki 1.7 nM
CCCOc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4069736 Ki 1.7 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4785488 IC50 1.71 nM
CC1CCC(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)CC1 CHEMBL5418891 IC50 1.73 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1CCc1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317498 Ki 1.8 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cncc3ccccc23)CC1 CHEMBL3393840 Ki 1.8 nM
Cc1cccc(N2CCN(c3cc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)c1 CHEMBL3627931 Ki 1.8 nM
CCCCCCSc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627947 Ki 1.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1OC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4072701 Ki 1.8 nM
Cc1ccc(CN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)S(=O)(=O)c2ccccc2)cc1 CHEMBL3769458 Ki 1.85 nM
CC(C)c1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)c1 CHEMBL5439218 IC50 1.86 nM
CC(C)(C)c1ccc(-c2cc(Nc3ccc4cccnc4c3)ncn2)cc1 CHEMBL226672 IC50 1.9 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)c4cc(I)c(O)c(OC)c4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL438313 EC50 1.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442928 Ki 1.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SC1CCCCC1C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442917 Ki 1.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1-c1cccc(F)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629231 Ki 1.9 nM
CCCCSc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627945 Ki 1.9 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1N1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4073205 Ki 1.9 nM
CCCCCc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4069267 Ki 1.9 nM
CC1CCN(c2nc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL4085410 Ki 1.9 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3ccc(F)c(Cl)c3)cccc21 CHEMBL4764786 Ki 1.9 nM
O=C(NCc1ccc(C(F)(F)F)nc1SC1CCCCC1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5432992 IC50 1.92 nM
O=C(NCc1ccc(C(F)(F)F)nc1-c1ccc(F)cc1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4781065 IC50 1.93 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccccc1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770027 Ki 1.99 nM
C=CCCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL313885 Log EC50 1.995 nM
COc1cc(CNC(=O)/C=C(\C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)ccc1O CHEMBL124415 Log EC50 1.995 nM
COc1cc(/C=C/C(=O)N2CCCCC2)ccc1O CHEMBL1095331 pEC50 1.995 nM
Cc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)c(F)c1 CHEMBL1807878 pIC50 1.995 nM
O=C(NCc1ccc(Cl)c(Cl)c1)Nc1cccc2ccc(O)cc12 CHEMBL358953 Ki 2.0 nM
COc1ccc2c(c1)CCC(NC(=O)Nc1cccc3cnccc13)C2Cc1cccc(Cl)c1 CHEMBL400312 Ki 2.0 nM
COc1ccc2c(c1)CCC(NC(=O)Nc1cccc3cnccc13)C2Cc1ccc(C(F)(F)F)cc1 CHEMBL436638 Ki 2.0 nM
C=CCC1c2ccc(F)cc2CCC1NC(=O)Nc1cccc2cnccc12 CHEMBL251182 Ki 2.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2c(Cl)cccc2C1Cc1ccccc1 CHEMBL400069 Ki 2.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2cc(Br)ccc2C1Cc1ccccc1 CHEMBL250558 Ki 2.0 nM
O=C(NCc1ccc(C(F)(F)F)cc1)Nc1cccc2cnccc12 CHEMBL104028 IC50 2.0 nM
CC(C)CNc1nc(Nc2ccc(C(F)(F)F)cc2)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 CHEMBL517566 IC50 2.0 nM
C[C@@H]1CN(Cc2nc(Nc3ccc(C(F)(F)F)nc3)c3ccc(-c4ncccc4C(F)(F)F)cc3n2)C[C@H](C)O1 CHEMBL456128 IC50 2.0 nM
C[C@@H]1CN(CCCc2nc(Nc3ccc(C(F)(F)F)cc3)c3ccc(-c4ncccc4C(F)(F)F)cc3n2)C[C@H](C)O1 CHEMBL446258 IC50 2.0 nM
COCCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL456152 IC50 2.0 nM
N#Cc1ccc(-c2nc(Nc3cccc4c3CC(O)CC4)oc2-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL1173690 IC50 2.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(OC(=O)C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177414 Ki 2.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccsc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317485 Ki 2.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3cnccc23)c2cc(F)ccc2O1 CHEMBL3326569 IC50 2.0 nM
CC(C)(C)c1ccc(/C=C/c2nc3cc(-c4ccccc4NS(C)(=O)=O)ccc3[nH]2)cc1 CHEMBL3426347 IC50 2.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCN(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629500 Ki 2.0 nM
CCCOc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627935 Ki 2.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC[C@H](c4cccc(F)c4)C3)c(F)ccc2cn1 CHEMBL3644131 IC50 2.0 nM
CC1CCCN1c1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 CHEMBL3907261 IC50 2.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)Nc1cccc2ccc(O)cc12 CHEMBL151446 Ki 2.1 nM
OC1CCc2c(Br)ccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 CHEMBL402637 IC50 2.1 nM
FC(F)(F)c1ccc(Nc2nc(CN3CCOCC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL458058 IC50 2.1 nM
CCc1nc(Nc2cccc3c2CC(O)CC3)oc1-c1ccc(C(F)(F)F)cc1 CHEMBL1173242 IC50 2.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ncccc2Cl)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2179154 Ki 2.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(CN(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177415 Ki 2.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385228 Ki 2.1 nM
CC(C)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385407 Ki 2.1 nM
CCC/C=C\c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3314386 Ki 2.1 nM
C[C@H](C(=O)NCc1cc(C(C)(C)C)nn1-c1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689035 Ki 2.1 nM
Cc1cc(NC(=O)N2CC=C(c3ccc(-c4nnc(CO)o4)cc3Cl)CC2)ccc1C(F)(F)F CHEMBL3959317 IC50 2.1 nM
CC(C)COc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4101174 Ki 2.1 nM
COc1ccc(CN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)S(=O)(=O)c2ccccc2)cc1 CHEMBL3770852 Ki 2.14 nM
O=C(NCc1ccc(C(F)(F)F)nc1SC1CCCCC1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4779863 IC50 2.15 nM
O=C(NCc1ccc(C(F)(F)F)nc1OCC1CCCC1)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4796057 IC50 2.18 nM
FC(F)(F)c1ccc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)ccc23)nc1 CHEMBL1089119 IC50 2.2 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1cccc2ccc(O)cc12 CHEMBL1779687 IC50 2.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1/C=C/c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317495 Ki 2.2 nM
COc1cc(C(C)C(=O)NCc2cc(C(C)(C)C)nn2-c2cccc(Cl)c2)ccc1NS(C)(=O)=O CHEMBL3689047 Ki 2.2 nM
CCCCCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4077828 Ki 2.2 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]ncc23)n(-c2ccc(F)cc2)n1 CHEMBL4762740 Ki 2.2 nM
O=C(NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5432397 IC50 2.24 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ccc(C(F)(F)F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2179151 Ki 2.3 nM
COc1ccc(CSc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL2442923 Ki 2.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442920 Ki 2.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCCOc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442900 Ki 2.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629487 Ki 2.3 nM
COc1ccc(CSc2cc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3629222 Ki 2.3 nM
CCCCCSc1cc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627946 Ki 2.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(CC1CCCCC1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770908 Ki 2.3 nM
Cn1c(=O)ccc2c(NC(=O)N[C@@H]3CC[C@@H](c4ccccc4F)C3)cccc21 CHEMBL3644136 IC50 2.3 nM
CC(C)Oc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4064288 Ki 2.3 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(Cl)c2)CC1 CHEMBL4129195 Ki 2.3 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3cccc(Cl)c3)cccc21 CHEMBL4752981 Ki 2.3 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CC(O)CO)CC1 CHEMBL5418316 IC50 2.31 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccc(F)cc1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3771102 Ki 2.32 nM
CCCCCc1ccc(C(=O)Nc2cccc3cnccc23)cc1 CHEMBL102073 IC50 2.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ccccc2F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2179149 Ki 2.4 nM
COC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177408 Ki 2.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CC=C(c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177439 Ki 2.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(c2cccc(F)c2)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3427103 Ki 2.4 nM
C=CC(=O)N(c1ccc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc1F)S(C)(=O)=O CHEMBL4129405 Ki 2.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(Cl)c(N)c(Cl)c2)CC1 CHEMBL4251335 Ki 2.4 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCCC1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5440062 IC50 2.49 nM
CC(C)(C)c1ccc(/C=C/C(=O)Nc2ccc3c(c2)NC(=O)CC3)cc1 CHEMBL195875 IC50 2.5 nM
COc1ccc(N2CCN(c3nc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)cc1 CHEMBL2179152 Ki 2.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385230 Ki 2.5 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385229 Ki 2.5 nM
CCCCCSc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442895 Ki 2.5 nM
Cc1c(C(F)(F)F)nn(-c2cccc(Cl)c2)c1CNC(=O)C(C)c1ccc(CNS(C)(=O)=O)c(F)c1 CHEMBL3689065 Ki 2.5 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1SC1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4096530 Ki 2.5 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1OC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4103769 Ki 2.5 nM
CCCN(CCC)c1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4061913 Ki 2.5 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1ccc(Cl)cc1)Nc1cccc2[nH]ncc12 CHEMBL4752186 Ki 2.5 nM
COc1cc(CNC(=O)C2CC2(C)CCCC(C)CCCC(C)CCCC(C)C)ccc1O CHEMBL332105 Log EC50 2.512 nM
COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O CHEMBL294199 pEC50 2.512 nM
COc1cc(/C=C/C(=O)N2CCOCC2)ccc1O CHEMBL1097704 pEC50 2.512 nM
COc1cc(/C=C/C(=O)N2CCSCC2)ccc1O CHEMBL1096703 pEC50 2.512 nM
CC(C)[C@H](CO)NCc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)cc1 CHEMBL1761700 pIC50 2.512 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC[C@H]1C(=O)OC(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178071 Ki 2.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1cc(Cl)cc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385237 Ki 2.6 nM
COc1ccc(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL2385232 Ki 2.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SC1CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442919 Ki 2.6 nM
CC(C)COc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4793646 IC50 2.6 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2c(F)cccc2Cl)CC1 CHEMBL4862169 Ki 2.6 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5429834 IC50 2.63 nM
CC(C)c1cccc(NC(=O)N2CCC[C@H]2c2ncc(-c3ccccc3)s2)c1 CHEMBL5181908 IC50 2.66 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1Cc2ccccc2C1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385245 Ki 2.7 nM
CCCCCCOc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4081355 Ki 2.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(N)(=O)=O)c(F)c2)CC1 CHEMBL4130073 Ki 2.7 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3ccc(Cl)cc3)cccc21 CHEMBL4784515 Ki 2.7 nM
CCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4785624 IC50 2.72 nM
CCCN(CCC)c1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2c(=O)[nH]ccc12 CHEMBL4789932 EC50 2.79 nM
O=C(NCc1ccc(Cl)cc1Cl)Nc1cccc2ccc(O)cc12 CHEMBL147028 Ki 2.8 nM
O=C(NCc1ccc(N2CCCCCC2)c(F)c1)Nc1cccc2cnccc12 CHEMBL231518 IC50 2.8 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ncccc2C(F)(F)F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177398 Ki 2.8 nM
Cc1ccc(Oc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL2385222 Ki 2.8 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(C#Cc3ccccc3)nc2c1 CHEMBL3426378 IC50 2.8 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(CCc3ccc(C(F)(F)F)cc3)nc2c1 CHEMBL3426376 IC50 2.8 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629490 Ki 2.8 nM
CCCCCc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4087871 Ki 2.8 nM
Cc1ccc(-n2nc(C(F)(F)F)cc2CNC(=O)Nc2cccc3[nH]ncc23)cc1C CHEMBL4788051 Ki 2.8 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)n(-c2cccc(Cl)c2)n1 CHEMBL5428310 IC50 2.85 nM
OC1COc2c(Cl)ccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 CHEMBL258117 IC50 2.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCCC1C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177426 Ki 2.9 nM
CC1CCC(Oc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2385419 Ki 2.9 nM
CC1CCN(CCCSc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2442905 Ki 2.9 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1OCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4098702 Ki 2.9 nM
CC(C)(C)c1cc(CNC(=O)Cc2ccc3c(c2)CCC3)n(-c2cccc(Cl)c2)n1 CHEMBL4649748 Ki 2.9 nM
CC(F)(F)c1cc(CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)n(-c2cccc(Cl)c2)n1 CHEMBL5411659 IC50 2.93 nM
O=C(Nc1ccc([N+](=O)[O-])cc1)N1CCN(c2ncccc2C(F)(F)F)CC1 CHEMBL362673 IC50 3.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCN(c2ncccc2C(F)(F)F)CC1 CHEMBL179739 IC50 3.0 nM
O=C(Nc1ccc(C(F)(F)F)cn1)N1CCN(c2ccccc2C(F)(F)F)CC1 CHEMBL177428 IC50 3.0 nM
Oc1cc2c(cc1O)CN(C(=S)NCCc1ccc(Cl)cc1)CCC2 CHEMBL391997 IC50 3.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(-c2ncccc2C(F)(F)F)cc1 CHEMBL378563 IC50 3.0 nM
CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3F)cc2)cc1 CHEMBL214331 IC50 3.0 nM
COc1ccc2c(c1)CCC(NC(=O)Nc1cccc3cnccc13)C2Cc1ccccc1 CHEMBL250149 Ki 3.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCc2cc(C(F)(F)F)ccc21 CHEMBL254866 IC50 3.0 nM
Cc1nc(Nc2ccc(C(F)(F)F)c(Cl)c2)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 CHEMBL465990 IC50 3.0 nM
FC(F)(F)c1ccc(Nc2nc(NCC3CC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 CHEMBL460373 IC50 3.0 nM
FC(F)(F)c1ccc(Nc2nc(CCCN3CCOCC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL456570 IC50 3.0 nM
CC(C)(C)c1cccc2c1OCC[C@H]2NC(=O)Nc1cccc2[nH]ncc12 CHEMBL1684275 IC50 3.0 nM
CC(C)OC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177412 Ki 3.0 nM
CC1CC(C)CC(Oc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C1 CHEMBL2385242 Ki 3.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCCCN1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442904 Ki 3.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC(C)(C)Oc4cc(F)ccc43)cccc2cn1 CHEMBL3326581 IC50 3.0 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407953 Ki 3.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNC(=O)OC(C)(C)C)c(Cl)c2)c1 CHEMBL3695689 Ki 3.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(N)(=O)=O)c(F)c2)c1 CHEMBL3695695 Ki 3.0 nM
CN1C(=O)NCc2c(NC(=O)N[C@@H]3C[C@@](C)(C(F)(F)F)Oc4ccccc43)cccc21 CHEMBL3682254 IC50 3.0 nM
CC1CCCCN1c1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 CHEMBL3956803 IC50 3.0 nM
CC(O)CSc1nc2c(c(Nc3ccc(S(=O)(=O)C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 CHEMBL3961217 IC50 3.0 nM
CC(C)c1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c(=O)[nH]ccc23)c1 CHEMBL4789599 EC50 3.07 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1C1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4102515 Ki 3.1 nM
CCCCCSc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4095591 Ki 3.1 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCOCCO)CC1 CHEMBL5397357 IC50 3.11 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCNS(C)(=O)=O)CC1 CHEMBL5435141 IC50 3.11 nM
CCCS(=O)(=O)N(Cc1ccccc1)c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3771317 Ki 3.13 nM
COc1cc(CNC(=O)CCCCCCCCC2CC2)ccc1O CHEMBL126095 Log EC50 3.162 nM
CCCCCC[C@@H](O)C/C=C\CCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL122849 Log EC50 3.162 nM
CCCCCCCC/C=C\CCCCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL121925 Log EC50 3.162 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1CNC1CC1 CHEMBL1761691 pIC50 3.162 nM
CC(C)(CO)CNCc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)cc1 CHEMBL1761702 pIC50 3.162 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1onc(-c2ccc(Cl)c(F)c2)c1Cl CHEMBL1807883 pIC50 3.162 nM
CCCCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4776492 IC50 3.19 nM
Cc1nc(Nc2cccc3c2CC(O)CC3)oc1-c1ccc(C(F)(F)F)cc1 CHEMBL1172953 IC50 3.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1ccc(C(F)(F)F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385231 Ki 3.2 nM
Cc1ccc(CSc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL2442922 Ki 3.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(N(C)C)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319114 Ki 3.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1SCc1ccco1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629223 Ki 3.2 nM
CCCCSc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4076319 Ki 3.2 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(Br)c2)CC1 CHEMBL4127798 Ki 3.2 nM
CC1(c2cc(CNC(=O)Nc3cccc4c3ccc(=O)n4CCO)n(-c3cccc(Cl)c3)n2)CC1 CHEMBL5434166 IC50 3.27 nM
Cc1ccc(CN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)S(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL3770685 Ki 3.28 nM
O=C(NCc1ccc(N2[C@@H]3CCC[C@H]2CC3)cc1)Nc1cccc2cnccc12 CHEMBL231206 IC50 3.3 nM
O=C(NCc1ccc(N2CCCCCC2)cc1)Nc1cccc2cnccc12 CHEMBL387996 IC50 3.3 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1cccc2c1CC(O)CC2 CHEMBL2024668 IC50 3.3 nM
Cc1ccc(N2CCN(c3nc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)cc1 CHEMBL2179148 Ki 3.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCCCN1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442903 Ki 3.3 nM
Cc1cc2c(NC(=O)N[C@@H]3CC[C@@H](c4ccccc4F)C3)c(F)ccc2cn1 CHEMBL3644137 IC50 3.3 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1c(Cl)ccc2ccc(O)cc12 CHEMBL1779839 IC50 3.4 nM
Cc1cccc(N2CCN(c3nc(C(F)(F)F)ccc3CNC(=O)C(C)c3ccc(NS(C)(=O)=O)c(F)c3)CC2)c1 CHEMBL2179147 Ki 3.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCC1CCN(C(=O)OC(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385219 Ki 3.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc2c(c1)OCO2)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317483 Ki 3.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(c2ccc(F)cc2)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL3427105 Ki 3.4 nM
CC(C)(C)c1ccc2c(c1)CC[C@H]2NC(=O)Nc1cccc2cnccc12 CHEMBL1628687 Kd 3.4 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1SCc1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4077270 Ki 3.4 nM
C[C@H](C(=O)NCc1ccc(C(C)(C)C)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4070318 Ki 3.4 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCCCC1)Nc1cccc2[nH]ncc12 CHEMBL1083396 IC50 3.5 nM
O=C(Nc1cccc(C(F)(F)F)c1)Nc1cccc2ccc(O)cc12 CHEMBL1779665 IC50 3.5 nM
CCCCOC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177411 Ki 3.5 nM
CCN(CC)c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178062 Ki 3.5 nM
Cc1cc2c(NC(=O)N[C@H]3CC[C@H](c4cccc(F)c4)C3)c(F)ccc2cn1 CHEMBL3644129 IC50 3.5 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCN(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4114101 IC50 3.5 nM
COc1ccc(CSc2nc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL4075950 Ki 3.5 nM
Cc1ccc(-n2nc(C(F)(F)F)cc2CNC(=O)Nc2cccc3c2cnn3C)cc1C CHEMBL4751370 Ki 3.5 nM
FC(F)(F)c1ccc(-c2cc(Oc3ccc4cccnc4c3)ncn2)cc1 CHEMBL226724 IC50 3.7 nM
CC(C)(C)c1ccc(C(=O)Nc2ccc3sc(CO)nc3c2)cc1 CHEMBL2088399 IC50 3.7 nM
CCc1ccc(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL2385226 Ki 3.7 nM
CC(C(=O)NCc1cc(C(C)(C)C)nn1-c1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3689034 Ki 3.7 nM
FC(F)(F)c1ccc(Nc2nc(N3CCOCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 CHEMBL1289607 IC50 3.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCC(Cc2ccccc2)(N(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4586277 Ki 3.79 nM
Cc1cc2c(NC(=O)NCc3ccc(N4CCCCCC4)cc3)cccc2cn1 CHEMBL427266 IC50 3.8 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC2(CC1)CC(C(C)(C)C)=NO2)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177416 Ki 3.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1OCc1ccc(F)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4096492 Ki 3.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1OCC(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4083176 Ki 3.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1SCc1ccccc1Cl)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4099896 Ki 3.8 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1ccc(C(F)(F)F)cc1)Nc1cccc2[nH]ncc12 CHEMBL4764743 Ki 3.8 nM
O=C(Cc1ccc(Cl)c(Cl)c1)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1 CHEMBL4851805 Ki 3.8 nM
CSc1cccc(NC(=O)Nc2cccc3ccc(O)cc23)c1 CHEMBL191990 IC50 3.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(C(=O)c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177403 Ki 3.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCc1cccc(C(F)(F)F)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442925 Ki 3.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCN(c2cccc(C(F)(F)F)c2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627932 Ki 3.9 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3ccc(C(F)(F)F)cc3)cccc21 CHEMBL4759747 Ki 3.9 nM
COc1cc(CNC(=O)/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)ccc1O CHEMBL124163 Log EC50 3.981 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1onc(-c2ccc(C(F)(F)F)cc2)c1Cl CHEMBL1807882 pIC50 3.981 nM
CCC(C)(C)c1ccc(CCC(=O)Nc2cccc3cnccc23)cc1 CHEMBL104623 Ki 4.0 nM
O=C(NCc1ccc(Cl)c(Cl)c1)Nc1cccc2cnccc12 CHEMBL104757 IC50 4.0 nM
CC(NC(=O)Nc1cccc2ccc(O)cc12)c1ccc(C(F)(F)F)cc1 CHEMBL357738 Ki 4.0 nM
O=c1c2ccc(-c3ncccc3C(F)(F)F)cc2[nH]n1-c1ccc(C(F)(F)F)cc1 CHEMBL3144710 IC50 4.0 nM
O=C(NCC(Cc1ccccc1)c1ccc(C(F)(F)F)cc1)Nc1cccc2cnccc12 CHEMBL398671 Ki 4.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2ccccc2C1Cc1ccccc1 CHEMBL249946 Ki 4.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2cc(F)ccc2C1Cc1cccs1 CHEMBL251181 Ki 4.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2cc(F)ccc2C1Cc1ccccc1 CHEMBL250557 Ki 4.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCc2cc(C3CC3)ccc21 CHEMBL255045 IC50 4.0 nM
OCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL497649 IC50 4.0 nM
O=C(Nc1cccc2[nH]ncc12)N[C@@H]1CCOc2cc(C(F)(F)F)ccc21 CHEMBL1684271 IC50 4.0 nM
CC(=O)OC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177413 Ki 4.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3cnccc23)c2ccccc2O1 CHEMBL3326575 IC50 4.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3cnccc23)c2ccc(F)cc2O1 CHEMBL3326570 IC50 4.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1Cl)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3629225 Ki 4.0 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(C)(=O)=O)cc2)CC1 CHEMBL3694599 Ki 4.0 nM
CCS(=O)(=O)NCc1ccc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc1F CHEMBL3694610 Ki 4.0 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(N)(=O)=O)c(F)c2)CC1 CHEMBL3694615 Ki 4.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC[C@H](c4ccccc4)C3)c(F)ccc2cn1 CHEMBL3644063 IC50 4.0 nM
O=C(Nc1cccc2c1C[C@H](O)CC2)N[C@H]1CC[C@H](c2ccccc2)C1 CHEMBL3646685 IC50 4.0 nM
O=C(Nc1cccc2c1C[C@H](O)CC2)N[C@@H]1CC[C@H](c2ccccc2)C1 CHEMBL3646691 IC50 4.0 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1)c1ccc(CNS(C)(=O)=O)c(F)c1 CHEMBL3695683 Ki 4.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(C)(=O)=O)c(C)c2)c1 CHEMBL3695698 Ki 4.0 nM
C[C@]1(C(F)F)C[C@@H](NC(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccc(Cl)cc2O1 CHEMBL3677329 IC50 4.0 nM
O=C1CCc2ccc(NC(=O)N[C@@H]3CCc4cc(C(F)(F)F)ccc43)cc2N1 CHEMBL3677333 IC50 4.0 nM
CC(C(=O)NCc1cc(C(C)(C)C)nn1-c1cccc(Cl)c1)c1ccc(CNS(C)(=O)=O)c(F)c1 CHEMBL3689051 Ki 4.0 nM
Fc1cc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)ccc1C(F)(F)F CHEMBL3980089 IC50 4.0 nM
CC(C)(C)c1ccc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1[N+](=O)[O-] CHEMBL3951149 IC50 4.0 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1SCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4080952 Ki 4.0 nM
CCCCOc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4793500 IC50 4.0 nM
CC(C)(C)c1cc(CNC(=O)Cc2cccc(Cl)c2Cl)n(-c2cccc(Cl)c2)n1 CHEMBL4876590 Ki 4.0 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(C(F)(F)F)cc3)nc2c1 CHEMBL2364618 IC50 4.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(c2ncccc2Cl)CC1C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177397 Ki 4.1 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1SCC(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4061629 Ki 4.1 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc2c(c1)CCC2 CHEMBL4648896 Ki 4.1 nM
CC(C)c1ccc(-n2nc(C(F)(F)F)cc2CNC(=O)Nc2cccc3[nH]ncc23)cc1 CHEMBL4796589 Ki 4.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177438 Ki 4.2 nM
COc1ccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1F CHEMBL3317479 Ki 4.2 nM
CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1OCc1ccccn1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407952 Ki 4.2 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c2ccc(=O)n3CCN2CCOCC2)CC1 CHEMBL5405791 IC50 4.29 nM
CC(C)(C)CCc1cc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]ncc12 CHEMBL1086278 IC50 4.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCC(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442898 Ki 4.3 nM
FC(F)(F)c1cnc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)ccc23)nc1 CHEMBL1214147 IC50 4.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(Nc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177108 Ki 4.4 nM
COc1cc(CC(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc(Br)c1N CHEMBL3681223 Ki 4.4 nM
CCCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4085682 Ki 4.4 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1OCc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4069604 Ki 4.4 nM
CCS(=O)(=O)Nc1ccc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc1F CHEMBL4128156 Ki 4.4 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]c(=O)ccc23)n(-c2cccc(Cl)c2)n1 CHEMBL4780532 IC50 4.41 nM
CCOCc1nc(Nc2ccc(C(F)(F)F)nc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL456961 IC50 4.5 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(C#Cc3ccc(C(F)(F)F)cc3)nc2c1 CHEMBL3426379 IC50 4.5 nM
O=C1COc2c(cccc2NC(=O)N[C@@H]2CC(CF)(CF)Oc3cc(Cl)ccc32)N1 CHEMBL3682410 IC50 4.5 nM
Cn1ncc2c(NC(=O)NCc3cc(C(C)(C)C)nn3-c3ccc(F)cc3)cccc21 CHEMBL4751403 Ki 4.5 nM
O=C(CCc1ccc(Cl)c(Cl)c1)Nc1cccc2ccc(O)cc12 CHEMBL348001 Ki 4.6 nM
O=C(NCc1ccc(N2CCCCCC2)c(C(F)(F)F)c1)Nc1cccc2cnccc12 CHEMBL397272 IC50 4.6 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)CCc4ccc(O)c(OC)c4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL391598 EC50 4.6 nM
O=C(NCc1ccc(N2CCCCCCC2)cc1)Nc1cccc2cnccc12 CHEMBL230998 IC50 4.7 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)Cc4ccccc4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL391808 EC50 4.7 nM
O=C(NCc1cc(C(F)(F)F)nn1-c1cccc(F)c1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5401266 IC50 4.72 nM
Cc1nc(Nc2cccc3c2C[C@@H](O)CC3)oc1-c1ccc(C(F)(F)F)cc1 CHEMBL1173241 IC50 4.8 nM
CCC1CCC(Oc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2385239 Ki 4.8 nM
C=CC(=O)Nc1c(F)cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)cc1I CHEMBL3685849 Ki 4.8 nM
O=C(Nc1ccc(Cl)c(Cl)c1)Nc1cccc2ccc(O)cc12 CHEMBL1779683 IC50 4.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OCc1cccc(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385234 Ki 4.9 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCc1ccccc1Cl)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442924 Ki 4.9 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(/C=C/c3cccc(C(F)(F)F)c3)nc2c1 CHEMBL3426361 IC50 4.9 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3ccc(F)c(F)c3)cccc21 CHEMBL4752767 Ki 4.9 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cccc(Cl)c2Cl)CC1 CHEMBL4855670 Ki 4.9 nM
CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3[N+](=O)[O-])cc2)cc1 CHEMBL183045 IC50 5.0 nM
O=C(NCC(Cc1ccccc1)c1ccc(F)cc1)Nc1cccc2cnccc12 CHEMBL250370 IC50 5.0 nM
O=C(Nc1cccc2cnccc12)NC1CCc2ccc(Cl)cc2C1Cc1ccccc1 CHEMBL250762 Ki 5.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCc2c1ccc(F)c2N1CCOCC1 CHEMBL399638 IC50 5.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCc2c(C3CC3)cccc21 CHEMBL251922 IC50 5.0 nM
O=C(Nc1ccc2c(c1)NC(=O)C(CCO)O2)C1CCN(c2cc(F)c(F)c(F)c2)CC1 CHEMBL446545 IC50 5.0 nM
CS(=O)(=O)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 CHEMBL467851 IC50 5.0 nM
CC(C)(C)CCc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]ncc12 CHEMBL1083712 IC50 5.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCOc2c1cccc2C(F)(F)F CHEMBL1684253 IC50 5.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCOc2c(OC(F)(F)F)cccc21 CHEMBL1684254 IC50 5.0 nM
CC(C)(C)c1cccc2c1OCCC2NC(=O)Nc1cccc2[nH]ncc12 CHEMBL1684255 IC50 5.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1Cc2ccccc2C1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177422 Ki 5.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc2c(c1)OCCO2)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317482 Ki 5.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC(CF)(CF)Oc4cc(C5CC5)ccc43)cccc2cn1 CHEMBL3326589 IC50 5.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC(CF)(CF)Oc4cc(F)ccc43)cccc2cn1 CHEMBL3326587 IC50 5.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC(C)(C)Oc4c3ccc(C(F)(F)F)c4F)cccc2cn1 CHEMBL3326584 IC50 5.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC(C)(C)Oc4c3ccc(F)c4F)cccc2cn1 CHEMBL3326582 IC50 5.0 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(C)(=O)=O)c(F)c2)CC1 CHEMBL3694601 Ki 5.0 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(C)(=O)=O)c(Cl)c2)CC1 CHEMBL3694603 Ki 5.0 nM
Cc1cc(NC(=O)NCc2ccc(C(F)(F)F)nc2N2CCC(C)CC2)ccc1CNS(C)(=O)=O CHEMBL3694608 Ki 5.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC[C@@H](c4ccccc4)C3)c(F)ccc2cn1 CHEMBL3644076 IC50 5.0 nM
O=C(Nc1cccc2c1C[C@@H](O)CC2)N[C@@H]1CC[C@H](c2ccccc2)C1 CHEMBL3646687 IC50 5.0 nM
O=C(Nc1cccc2c1C[C@H](O)CC2)N[C@@H]1CC[C@@H](c2ccccc2)C1 CHEMBL3646689 IC50 5.0 nM
O=C(Nc1cccc2c1C[C@@H](O)CC2)N[C@@H]1CC[C@@H](c2ccccc2)C1 CHEMBL3646690 IC50 5.0 nM
O=C(Nc1nc2cc(F)ccc2s1)N1CCC(c2ncc(CC(O)CO)cc2Cl)CC1 CHEMBL3671860 IC50 5.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1)c1ccc(CNS(C)(=O)=O)c(F)c1 CHEMBL3695682 Ki 5.0 nM
CN1Cc2c(NC(=O)N[C@@H]3CC(CF)(CF)Oc4cc(Cl)ccc43)cccc2N(C)C1=O CHEMBL3682256 IC50 5.0 nM
CC(Oc1nc2c(c(Nc3ccc(S(=O)(=O)N4CCCC4)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2)C1CCCCC1 CHEMBL3945933 IC50 5.0 nM
COc1cc(CNC(=O)CCCc2ccc(I)s2)ccc1O CHEMBL5422020 IC50 5.0 nM
C[C@H](NC(=O)Cn1cnc2ccc(F)c(F)c21)c1ccc(C(C)(C)C)cc1 CHEMBL5398782 IC50 5.0 nM
CCCCCC[C@@H](O)CCCCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL126172 Log EC50 5.012 nM
CCCCCC[C@@H](O)CC1CC1CCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL124613 Log EC50 5.012 nM
CN(Cc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)cc1)C[C@@H]1CCCO1 CHEMBL1761706 pIC50 5.012 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(Cl)cc2)c1Cl CHEMBL1807876 pIC50 5.012 nM
CC(C)(C)c1nc(-c2cccc(Cl)c2)c(CNC(=O)Nc2ccc(CO)c(F)c2)s1 CHEMBL4448147 EC50 5.05 nM
CC(C)c1cccc(C(C)C)c1O CHEMBL526 IC50 5.05 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2042264 Ki 5.1 nM
CCC/C=C/n1nc(C(C)(C)C)cc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4205905 Ki 5.1 nM
O=C(NCc1ccc(N2CCCCCC2)cc1Cl)Nc1cccc2cnccc12 CHEMBL427111 IC50 5.2 nM
O=C(Cc1ccc2c(c1)CCC2)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1 CHEMBL4640107 Ki 5.2 nM
CCCN(CCC)c1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]c(=O)ccc12 CHEMBL4779220 IC50 5.21 nM
O=C(NCc1ccc(N2CCCC2)cc1)Nc1cccc2cnccc12 CHEMBL230896 IC50 5.3 nM
Cc1cc2c(NC(=O)N[C@H]3CC[C@@H](c4ccccc4F)C3)c(F)ccc2cn1 CHEMBL3644138 IC50 5.3 nM
O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)N1CCC(F)(c2ncc([C@H](O)CO)cc2F)CC1 CHEMBL4107976 IC50 5.3 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(O)c(N)c(F)c2)CC1 CHEMBL4239798 Ki 5.3 nM
CC(C)c1ccccc1NC(=O)N1CCC[C@H]1c1ncc(-c2ccccc2)s1 CHEMBL5189961 IC50 5.32 nM
O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc2ccc(O)cc12 CHEMBL1779666 IC50 5.4 nM
Cc1cc2c(NC(=O)N[C@@H]3CC[C@@H](c4cccc(F)c4)C3)c(F)ccc2cn1 CHEMBL3644139 IC50 5.4 nM
FC(F)(F)c1ccc(Nc2nc(N3CCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 CHEMBL1289500 IC50 5.4 nM
FC(F)(F)c1cnc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)ccc23)cn1 CHEMBL1214146 IC50 5.5 nM
CCCCCCSc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442896 Ki 5.6 nM
Cc1cc2c(NC(=O)N[C@@H]3CC[C@H](c4ccccc4F)C3)c(F)ccc2cn1 CHEMBL3644125 IC50 5.6 nM
COCCCOc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4096513 Ki 5.6 nM
O=C(NCc1ccc(N2CCCCCC2)cc1C(F)(F)F)Nc1cccc2cnccc12 CHEMBL231517 IC50 5.7 nM
O=C(Nc1cccc(Br)c1)Nc1cccc2ccc(O)cc12 CHEMBL1779675 IC50 5.7 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(Cl)cc3)nc2c1 CHEMBL3426364 IC50 5.7 nM
O=C(Nc1ccc(OC(F)(F)F)c(Cl)c1)N1CCC(F)(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4108837 IC50 5.7 nM
COc1ccccc1NC(=O)N1CCC[C@H]1c1nc(-c2ccc(F)cc2)cs1 CHEMBL5193097 IC50 5.71 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccco1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3317486 Ki 5.8 nM
COc1cc(OC)cc(-c2cc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c1 CHEMBL3629235 Ki 5.8 nM
C[C@@H]1CN(c2ncc([C@@H](O)CO)cc2F)CCN1C(=O)Nc1nc2ccccc2s1 CHEMBL4107019 IC50 5.8 nM
O=C(Nc1ccc(S(=O)(=O)C(F)(F)F)cc1)N1CCC(F)(c2ncc([C@@H](O)CO)cc2Cl)CC1 CHEMBL3932728 IC50 5.8 nM
O=C(Nc1ccc(OC(F)(F)F)cc1)N1CCN(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4107528 IC50 5.8 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 CHEMBL4648285 Ki 5.8 nM
O=C(NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccccc2)CC1)Nc1cccc2c(=O)[nH]ccc12 CHEMBL4787182 EC50 5.81 nM
O=C(NCc1cc(C2CC2)nn1-c1cccc(Cl)c1)Nc1cccc2c1ccc(=O)n2CCO CHEMBL5419961 IC50 5.81 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Cc1cc(I)c(O)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL595069 Ki 5.87 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1c(Cl)c(Cl)cc2ccc(O)cc12 CHEMBL1779840 IC50 5.9 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(OC(F)(F)F)cc3)nc2c1 CHEMBL3426363 IC50 5.9 nM
CC(C)(C)c1ccc(Nc2nc(-c3ccccc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 CHEMBL3935014 IC50 5.9 nM
CC(C)CCSc1nc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4083437 Ki 5.9 nM
O=C(NCc1ccc(Cl)cc1)Nc1cccc2cnccc12 CHEMBL102010 IC50 6.0 nM
O=C(NCCc1ccc(OC(F)(F)F)cc1)Nc1cccc2cnccc12 CHEMBL105252 Ki 6.0 nM
CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3C(F)(F)F)cc2)cc1 CHEMBL180902 IC50 6.0 nM
COc1ccc(C(CNC(=O)Nc2cccc3cnccc23)Cc2ccccc2)cc1 CHEMBL250368 Ki 6.0 nM
CC(C)(C)c1ccc2c(c1)CCC2NC(=O)Nc1cccc2[nH]ncc12 CHEMBL254867 IC50 6.0 nM
CC(C)(C)c1ccc(NC(=O)C2=CCN(c3ncccc3C(F)(F)F)CC2)cc1 CHEMBL518979 IC50 6.0 nM
FC(F)(F)c1ccc(Nc2nc(CNC3CCCCC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL456764 IC50 6.0 nM
CC(C)(C)COc1nc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]ncc12 CHEMBL1084293 IC50 6.0 nM
CC(C)(F)CCc1cc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]ncc12 CHEMBL1086277 IC50 6.0 nM
CN1CCC(NC(=O)Nc2cccc3[nH]ncc23)c2cccc(C(C)(C)C)c21 CHEMBL1684262 IC50 6.0 nM
CCC1(CC)C[C@@H](NC(=O)Nc2cccc3cnccc23)c2cc(F)ccc2O1 CHEMBL3326577 IC50 6.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3cnccc23)c2ccc(OC(F)(F)F)cc2O1 CHEMBL3326576 IC50 6.0 nM
NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(CCc3ccc(C(F)(F)F)cc3)nc2c1 CHEMBL3426377 IC50 6.0 nM
NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(OC(F)(F)F)cc3)nc2c1 CHEMBL3426369 IC50 6.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(c1ccccc1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3771342 Ki 6.0 nM
O=C(Nc1cccc2c1C[C@@H](O)CC2)N[C@H]1CC[C@@H](c2ccccc2)C1 CHEMBL3646686 IC50 6.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(C)(=O)=O)c(F)c2)c1 CHEMBL3695699 Ki 6.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(N)(=O)=O)c(F)c2)c1 CHEMBL3695696 Ki 6.0 nM
FC(F)(F)c1ccc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 CHEMBL3951500 IC50 6.0 nM
C[C@H](C(=O)NCc1ccc(C(C)(C)C)cc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4079990 Ki 6.0 nM
COc1cccc(COc2nc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c1 CHEMBL4087890 Ki 6.0 nM
FC(F)(F)c1ccc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL1089118 IC50 6.1 nM
O=C(Nc1cccc(Cl)c1)Nc1cccc2ccc(O)cc12 CHEMBL1779668 IC50 6.1 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC2(CC1)CC(c1ccccc1)=NO2)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177417 Ki 6.1 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cccc(Cl)c2)CC1 CHEMBL4866993 Ki 6.1 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3[nH]c(=O)ccc23)n(-c2cccc(F)c2)n1 CHEMBL4782987 IC50 6.17 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(Cc1ccccc1)S(=O)(=O)C(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3771109 Ki 6.19 nM
O=C(Nc1nc2ccc(F)cc2s1)N1CCN(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4113561 IC50 6.2 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1N1CCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4093885 Ki 6.2 nM
O=C(Cc1cccc(Cl)c1)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1 CHEMBL4872487 Ki 6.2 nM
C=C(C)[C@]12C[C@@H](C)[C@@]34O[C@](Cc5ccccc5)(O[C@@H]1[C@@H]3C=C(COC(=O)Oc1ccc(N)c(OC)c1)C[C@]1(O)C(=O)C(C)=C[C@@H]41)O2 CHEMBL2425550 EC50 6.28 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1cc(F)cc(F)c1 CHEMBL3689050 Ki 6.3 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC(F)(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4108952 IC50 6.3 nM
O=C(Cc1ccc(Cl)cc1)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1 CHEMBL4851412 Ki 6.3 nM
CCCCCCC(=O)CCCCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 CHEMBL122156 Log EC50 6.31 nM
CC(C)CNC(=O)/C=C/C=C/c1ccc2c(c1)OCO2 CHEMBL253973 pEC50 6.31 nM
COc1cc(/C=C/C(=O)NCC(C)C)ccc1O CHEMBL1096704 pEC50 6.31 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1Oc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385221 Ki 6.4 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3319107 Ki 6.4 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)n(-c2cccc(F)c2)n1 CHEMBL5440413 IC50 6.4 nM
CC(C)(C)c1ccc(/C=C/C(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 CHEMBL191607 IC50 6.5 nM
Cn1c(=O)ccc2c(NC(=O)N[C@@H]3CC[C@@H](c4cccc(F)c4)C3)cccc21 CHEMBL3644133 IC50 6.5 nM
COc1cc(CNC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)ccc1O CHEMBL3099609 Ki 6.58 nM
CCCCSc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4069261 Ki 6.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2ccc(Cl)c(Cl)c2)CC1 CHEMBL4859265 Ki 6.7 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1c(Cl)c(Br)cc2ccc(O)cc12 CHEMBL1779841 IC50 6.8 nM
CC(C)(C)c1ccc(Nc2nc(N3CCOCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 CHEMBL3968598 IC50 6.8 nM
CC(C)(C)c1cc(CNC(=O)Cc2cccc(F)c2F)n(-c2cccc(Cl)c2)n1 CHEMBL4856953 Ki 6.9 nM
O=C(NCc1ccc(F)c(F)c1)Nc1cccc2ccc(O)cc12 CHEMBL342300 Ki 7.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCc2c1cccc2N1CCC(C(F)(F)F)CC1 CHEMBL401329 IC50 7.0 nM
CN1CCC(NC(=O)Nc2cccc3[nH]ncc23)c2ccc(C(F)(F)F)cc21 CHEMBL254226 IC50 7.0 nM
FC(F)(F)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)cn1 CHEMBL463382 IC50 7.0 nM
Cn1ncc2c(NC(=O)NCc3ccc(C(F)(F)F)cc3CCC(C)(C)C)cccc21 CHEMBL1085324 IC50 7.0 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCCCBr)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442899 Ki 7.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3c2C[C@@H](O)CC3)c2ccc(F)cc2O1 CHEMBL3326574 IC50 7.0 nM
CC1(C)C[C@@H](NC(=O)Nc2cccc3c2C[C@H](O)CC3)c2ccc(F)cc2O1 CHEMBL3326573 IC50 7.0 nM
Cn1ncc2c(NC(=O)N[C@@H]3CC(C)(C)Oc4cc(F)ccc43)cccc21 CHEMBL3706671 IC50 7.0 nM
CC(C)(O)c1ccccc1-c1ccc2[nH]c(/C=C\c3ccc(C(F)(F)F)cc3)nc2c1 CHEMBL3426375 IC50 7.0 nM
NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(C(F)(F)F)cc3)nc2c1 CHEMBL3426368 IC50 7.0 nM
NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(/C=C/c3ccc(F)cc3)nc2c1 CHEMBL3426367 IC50 7.0 nM
Cc1cc2c(NC(=O)N[C@H]3CC[C@@H](c4ccccc4)C3)c(F)ccc2cn1 CHEMBL3644083 IC50 7.0 nM
COc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2-c2cccc(C)c2)ccc1CNC(=O)OC(C)(C)C CHEMBL3695691 Ki 7.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(CNS(N)(=O)=O)cc2)c1 CHEMBL3695697 Ki 7.0 nM
C[C@]1(C(F)(F)F)C[C@@H](NC(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccccc2O1 CHEMBL3677332 IC50 7.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC(F)(c2ncc(C(O)CO)cc2Cl)CC1 CHEMBL3962224 IC50 7.0 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3cccc(F)c3)cccc21 CHEMBL4762603 Ki 7.0 nM
FC(F)(F)c1ccc(Nc2ncnc3cc(-c4ncccc4C(F)(F)F)ccc23)cn1 CHEMBL1204401 IC50 7.1 nM
C[C@H](C(=O)NCc1ccc(C(F)(F)F)nc1N1CC[C@H](NC(=O)OC(C)(C)C)C1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177421 Ki 7.1 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3cccnc3c2)CC1 CHEMBL3393826 Ki 7.1 nM
CC(C)(C)c1cc(CNC(=O)Cc2ccc3c(c2)CCC3)n(-c2cccc(C(F)(F)F)c2)n1 CHEMBL4641056 Ki 7.1 nM
CC(C)c1cc(CNC(=O)Nc2cccc3c2ccc(=O)n3CCO)n(-c2cccc(Cl)c2)n1 CHEMBL5409855 IC50 7.17 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3cnccc3c2)CC1 CHEMBL3393828 Ki 7.2 nM
CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCOCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3627934 Ki 7.2 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C(=O)Nc2ccccc2)c(F)c1 CHEMBL3689052 Ki 7.2 nM
O=C(NCc1ccc(N2CCCCC2)cc1)Nc1cccc2cnccc12 CHEMBL230997 IC50 7.3 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(c1ccc(F)cc1)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3770191 Ki 7.3 nM
CN(C)C1(Cc2ccccc2)CCN(c2cc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3ccncc3c2)CC1 CHEMBL4453980 Ki 7.33 nM
CC(=O)NCCn1c(=O)ccc2c(NC(=O)NCc3ccc(C(F)(F)F)nc3N3CCC(C)CC3)cccc21 CHEMBL5433444 IC50 7.38 nM
O=C(N[C@H]1CCC[C@@H](O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1Cl CHEMBL1669531 IC50 7.4 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC(F)(c2ncc([C@@H](O)CO)cc2Cl)CC1 CHEMBL3925712 IC50 7.4 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4104231 Ki 7.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NC(=O)c3ccccc3)c(F)c2)CC1 CHEMBL4238685 Ki 7.4 nM
O=C(Nc1cccc([N+](=O)[O-])c1)Nc1cccc2ccc(O)cc12 CHEMBL1779673 IC50 7.5 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1c(Br)c(Br)cc2ccc(O)cc12 CHEMBL1779842 IC50 7.5 nM
C[C@@H](C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177436 Ki 7.5 nM
Cc1ccc(C(C(=O)NCc2ccc(C(F)(F)F)nc2SC2CCCCC2)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3427111 Ki 7.5 nM
CC(C)(C)c1cc(CNC(=O)Cc2ccc3c(c2)CCC3)n(-c2ccc(F)c(Cl)c2)n1 CHEMBL4637758 Ki 7.5 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(C(F)(F)F)c1)c1ccc2c(c1)CCC2 CHEMBL4634951 Ki 7.5 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1ccc(F)c(Cl)c1)c1ccc2c(c1)OCO2 CHEMBL4645802 Ki 7.5 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(Cl)c(Cl)c1 CHEMBL4864994 Ki 7.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385240 Ki 7.7 nM
CC(C)(C)c1cc(CNC(=O)Cc2ccccc2Cl)n(-c2cccc(Cl)c2)n1 CHEMBL4847072 Ki 7.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3cncnc3c2)CC1 CHEMBL3393833 Ki 7.8 nM
CC(C)(C)C(=O)OCC(CNC(=S)NCc1ccc(NS(C)(=O)=O)c(F)c1)Cc1ccccc1 CHEMBL5435976 Ki 7.8 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)CCc4cc(OC)c(O)cc4I)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL233915 EC50 7.9 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(O)c([N+](=O)[O-])c(F)c2)CC1 CHEMBL3685848 Ki 7.9 nM
O=C(Nc1ccc2cccnc2c1)c1ccc(-c2ccccc2)nc1 CHEMBL213390 Log IC50 7.943 nM
O=C(N[C@@H]1CCC[C@H](O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1CNCC1CC1 CHEMBL1761694 pIC50 7.943 nM
COCCN(C)Cc1c(C(=O)N[C@@H]2CCC[C@H](O)C2)noc1-c1ccc(C(F)(F)F)cc1 CHEMBL1761704 pIC50 7.943 nM
CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL388824 EC50 8.0 nM
CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3Cl)cc2)cc1 CHEMBL183752 IC50 8.0 nM
COc1ccc(CC2c3ccc(OC)cc3CCC2NC(=O)Nc2cccc3cnccc23)cc1 CHEMBL248762 Ki 8.0 nM
CN(c1ccc(C(=O)Nc2cnc3ccccc3c2)cc1)C1CCCCC1 CHEMBL408401 Ki 8.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)C1=CCN(c2ncccc2C(F)(F)F)CC1 CHEMBL522425 IC50 8.0 nM
FC(F)(F)c1ccc(Nc2nc(CN3CCN(C4CCCC4)CC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cc1 CHEMBL451895 IC50 8.0 nM
CC(C)(C)NCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 CHEMBL456546 IC50 8.0 nM
COCCCc1cc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]ncc12 CHEMBL1083713 IC50 8.0 nM
O=C(NCc1ccc(C(F)(F)F)cc1CCc1ccccc1)Nc1cccc2[nH]ncc12 CHEMBL1082460 IC50 8.0 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCOc2cc(OC(F)(F)F)ccc21 CHEMBL1684251 IC50 8.0 nM
COc1cccc(NC(=O)Nc2cccc3ccc(O)cc23)c1 CHEMBL1779672 IC50 8.0 nM
NS(=O)(=O)c1ccccc1-c1ccc2[nH]c(/C=C/c3cccc(OC(F)(F)F)c3)nc2c1 CHEMBL3426370 IC50 8.0 nM
O=C(Nc1cccc2[nH]ncc12)N[C@@H]1CC[C@H](c2cccc(F)c2)C1 CHEMBL3644120 IC50 8.0 nM
C[C@@H]1CC(F)(c2ncc(C[C@H](O)CO)cc2F)CCN1C(=O)Nc1nc2cc(Cl)ccc2s1 CHEMBL3671862 IC50 8.0 nM
Cn1c(=O)ccc2c(NC(=O)N[C@@H]3CCc4cc(Cl)ccc43)cccc21 CHEMBL3677394 IC50 8.0 nM
C[C@H]1Oc2c(NC(=O)N[C@@H]3CC(CF)(CF)Oc4cc(Cl)ccc43)cccc2NC1=O CHEMBL3682224 IC50 8.0 nM
Cc1ccc(-n2nc(C(C)(C)C)cc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 CHEMBL3684333 Ki 8.0 nM
CC(C(=O)NCc1cc(C(C)(C)C)nn1-c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4217897 Ki 8.0 nM
O=C(Nc1ccc(S(=O)(=O)C(F)(F)F)cc1)N1CC=C(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4110552 IC50 8.1 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1OC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4071681 Ki 8.1 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1N1CCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4101614 Ki 8.1 nM
O=C(Nc1cccc2[nH]ncc12)N[C@@H]1CC[C@@H](c2ccccc2F)C1 CHEMBL3644121 IC50 8.2 nM
OC1CCc2cccc(Nc3ncc(-c4ccc(C(F)(F)F)cc4)o3)c2C1 CHEMBL1173264 IC50 8.3 nM
FC(F)(F)c1ccc(Nc2ccnc3nc(-c4nnccc4C(F)(F)F)ccc23)nc1 CHEMBL1214266 IC50 8.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3ccncc3c2)CC1 CHEMBL3393827 Ki 8.4 nM
Cn1ncc2c(NC(=O)NCc3cc(C(F)(F)F)nn3-c3ccc(F)cc3)cccc21 CHEMBL4751349 Ki 8.4 nM
Cc1ccnnc1N1CCN(C(=O)Nc2ccc(C(C)(C)C)cc2)[C@H](C)C1 CHEMBL362548 IC50 8.5 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC2(CC1)C(=O)N(c1ccccn1)[C@H]2c1ccccc1 CHEMBL481025 IC50 8.5 nM
CC(C(=O)NCc1ccc(C(C)(C)C)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4091248 Ki 8.5 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)CCc4cc(I)c(O)c(OC)c4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL232947 EC50 8.6 nM
COc1ccc(-c2cc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1OC CHEMBL3629234 Ki 8.6 nM
Cc1cc2c(NC(=O)N[C@H]3CC[C@H](c4ccccc4F)C3)c(F)ccc2cn1 CHEMBL3644126 IC50 8.6 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1SCc1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2442921 Ki 8.7 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(=O)(=O)C(C)C)c(F)c2)CC1 CHEMBL4125699 Ki 8.7 nM
CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCN(Cc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2177399 Ki 8.8 nM
CC(C)(C)c1cc(CNC(=O)Cc2ccc(F)c(C(F)(F)F)c2)n(-c2cccc(Cl)c2)n1 CHEMBL4877286 Ki 8.8 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc3cnncc3c2)CC1 CHEMBL3393832 Ki 8.9 nM
Cc1cc2c(NC(=O)N[C@H]3CC[C@@H](c4cccc(F)c4)C3)c(F)ccc2cn1 CHEMBL3644140 IC50 8.9 nM
COCCN(C)c1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 CHEMBL3929759 IC50 8.9 nM
O=C(Nc1cccc2[nH]ncc12)NC1CCc2cc(Br)ccc21 CHEMBL255078 IC50 9.0 nM
Cc1cccc(Cl)c1Nc1nc2c(Nc3ccc(C(F)(F)F)cc3)ncnc2s1 CHEMBL468470 IC50 9.0 nM
Cc1nc2cc(NC(=O)c3ccc(-c4ccc(F)cc4)nc3C)ccc2s1 CHEMBL514691 IC50 9.0 nM
FC(F)(F)c1ccc(Nc2nc(CN3CCOCC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)nc1 CHEMBL457002 IC50 9.0 nM
O=C(NCc1ccc(C(F)(F)F)nc1Oc1ccccc1)Nc1cccc2[nH]ncc12 CHEMBL1085786 IC50 9.0 nM
O=C(NCc1ccc(C(F)(F)F)cc1Oc1ccccc1)Nc1cccc2[nH]ncc12 CHEMBL1082461 IC50 9.0 nM
CC(C)c1cc(C(F)(F)F)ccc1CNC(=O)Nc1cccc2[nH]ncc12 CHEMBL1086276 IC50 9.0 nM
OC1CCc2cccc(Nc3nc(Br)c(-c4ccc(C(F)(F)F)cc4)o3)c2C1 CHEMBL1172975 IC50 9.0 nM
CC(C)(C)c1ccc(Nc2ncnc3c2CCN(c2ncccc2C(F)(F)F)C3)cc1 CHEMBL1290369 IC50 9.0 nM
Cc1cc2c(NC(=O)N[C@@H]3CC(CF)(CF)Oc4cc(Cl)ccc43)cccc2cn1 CHEMBL3326588 IC50 9.0 nM
O=C(Nc1cccc2[nH]ncc12)N[C@@H]1CC[C@H](c2ccccc2)C1 CHEMBL3644064 IC50 9.0 nM
Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(N)(=O)=O)cc2)c1 CHEMBL3695694 Ki 9.0 nM
O=C(Nc1ccc(C(F)(F)F)c(F)c1)N1CCC(F)(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4112368 IC50 9.0 nM
O=C(Nc1ccc(C(F)(F)F)c(F)c1)N1CCC(F)(c2ncc([C@@H](O)CO)cc2F)CC1 CHEMBL3933640 IC50 9.0 nM
O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1cccc2ccc(O)c(F)c12 CHEMBL2024494 IC50 9.1 nM
CCCCNc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2178076 Ki 9.1 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2ccccc2Cl)CC1 CHEMBL4878230 Ki 9.1 nM
Cc1cc(C(F)(F)F)nc(N2CCC(Cc3ccccc3)CC2)c1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL3407955 Ki 9.2 nM
CC(C)c1ccc(/C=C/c2nc3cc(-c4ccccc4NS(C)(=O)=O)ccc3[nH]2)cc1 CHEMBL3426357 IC50 9.2 nM
Cc1cc(NC(=O)N2CC=C(c3ncc([C@H](O)CO)cc3F)CC2)ccc1OC(F)(F)F CHEMBL4108096 IC50 9.2 nM
CC(C)(C)c1cc(CNC(=O)Cc2ccc3c(c2)OCO3)n(-c2cccc(Cl)c2)n1 CHEMBL4644921 Ki 9.2 nM
O=C(Nc1ccccc1Br)N[C@@H]1CCN(c2ccc(C(F)(F)F)cn2)C1 CHEMBL207433 IC50 9.24 nM
O=C(NCc1cc(F)c(N2CCOCC2)c(F)c1)Nc1cccc2cnccc12 CHEMBL231619 IC50 9.3 nM
CC1CCN(c2ccc(CNC(=O)Nc3cccc4cnccc34)cc2)CC1 CHEMBL231104 IC50 9.3 nM
O=C(Nc1nc2ccc(Cl)cc2s1)N1CC=C(c2ncc([C@H](O)CO)cc2Cl)CC1 CHEMBL4108420 IC50 9.3 nM
C=C(C)[C@]12C[C@@H](C)[C@@]3(OCc4ccccc4)[C@@H](C=C(COC(=O)c4ccc(O)c(OC)c4)C[C@]4(O)C(=O)C(C)=C[C@@H]34)[C@H]1OCO2 CHEMBL391393 EC50 9.4 nM
CC(C)(C)c1ccc(NC(=O)N2CCC3(CC2)C(=O)N(c2ccccc2)[C@H]3c2ccccc2)cc1 CHEMBL479645 IC50 9.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cccc(F)c2F)CC1 CHEMBL4859520 Ki 9.4 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cnc3ccccc3c2)CC1 CHEMBL3393830 Ki 9.5 nM
Cn1ncc2c(NC(=O)NCc3cc(C(C)(C)C)nn3-c3ccc(Cl)cc3)cccc21 CHEMBL4785636 Ki 9.5 nM
CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(Cl)c(F)c1 CHEMBL4876351 Ki 9.5 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Nc2cccc3c(=O)[nH]ccc23)CC1 CHEMBL4800517 EC50 9.59 nM
CC(C)(C)c1cc(CNC(=O)Nc2cccc3c(=O)[nH]ccc23)n(-c2cccc(Cl)c2)n1 CHEMBL4776728 EC50 9.59 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2cc(F)c(N)c(F)c2)CC1 CHEMBL3681235 Ki 9.6 nM
CCOCCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL2385405 Ki 9.7 nM
O=C(CCc1ccc(Cl)cc1)Nc1cccc2ccc(O)cc12 CHEMBL151442 Ki 9.8 nM
Nc1cc2c(NC(=O)NCc3ccc(N4CCCCCC4)cc3)cccc2cn1 CHEMBL387579 IC50 9.8 nM
CC(C)(C)Oc1ccc(C(=O)Nc2ccc3sc(CO)nc3c2)cc1 CHEMBL2088393 IC50 9.8 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)[C@H](C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 CHEMBL2177430 Ki 9.8 nM
CC(C(=O)NCc1ccc(C(C)(C)C)cc1C1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 CHEMBL4075164 Ki 9.8 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2ccc(F)c(C(F)(F)F)c2)CC1 CHEMBL4858145 Ki 9.8 nM
CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2ccccc2F)CC1 CHEMBL4851854 Ki 9.9 nM