COc1ccc(CC(C)NCC(O)c2ccc(O)c(NC=O)c2)cc1 CHEMBL1256786 Potency 1.3 nM
CN(C)Cc1ccccc1 CHEMBL45591 Potency 1.6 nM
CN(C)CC/C=C1\c2ccccc2COc2ccccc21 CHEMBL860 Potency 2.0 nM
CCCCC[C@H](O)/C=C\[C@@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O CHEMBL1318789 Potency 2.5 nM
C[N+](C)(C)CC(=O)O CHEMBL95889 Potency 4.0 nM
ClC=C(Cl)Cl CHEMBL279816 Potency 4.0 nM
COc1ccccc1-c1nnc(NC(=O)C(C)SC2=NCCS2)s1 CHEMBL1597046 Potency 4.0 nM
NCCC[C@@H](CC(=O)N[C@@H]1CCNC[C@H]1C(=O)N[C@H](CC(=O)N[C@@H](CCC(=O)O)CC(=O)O)Cc1ccccc1)NC(=O)C[C@H](CO)NC(=O)[C@@H]1CNCC[C@H]1N CHEMBL1552133 Potency 5.0 nM
CC1=CC(=C(C#N)c2nc3ccccc3s2)C=C(C)N1Cc1ccco1 CHEMBL1580259 Potency 5.0 nM
COc1ccc(OC)c(NC(=O)CC(NCCC2=CCCCC2)C(=O)O)c1 CHEMBL1428273 Potency 5.0 nM
COc1ccccc1CN(Cc1cc2cc(C)ccc2nc1O)Cc1nnnn1CC1CCCO1 CHEMBL1378396 Potency 5.0 nM
CCCCN1C(=O)NC(=O)/C(=C(/CC)NCc2ccc3c(c2)OCO3)C1=O CHEMBL1302121 Potency 5.0 nM
CCN(CC)S(=O)(=O)c1ccc(C2CNC(=O)C2)cc1 CHEMBL1420813 Potency 5.0 nM
CC(C)NC[C@H](O)c1ccc(N)c(C#N)c1 CHEMBL1355090 Potency 5.0 nM
CCN(CC)S(=O)(=O)c1cc(C(=O)n2cccn2)c(Cl)cc1Cl CHEMBL1381609 Potency 5.0 nM
CCOC(=O)CN(C(=O)CNC(=O)c1ccco1)C(C(=O)NC1CCCC1)c1ccccc1OCC CHEMBL1353729 Potency 5.0 nM
CCCCCCCCC/C=C/CC1CC(=O)OC1=O CHEMBL87310 Potency 5.0 nM
CCN1CCN(CCCNC(=O)Cn2cc3c(n2)CCCC3)CC1 CHEMBL1541641 Potency 6.3 nM
C/C(Nc1cccc(F)c1)=C(/C#N)C(N)=O CHEMBL1336298 Potency 6.3 nM
CC(C)OC(=O)Cc1ccccc1 CHEMBL1449867 Potency 6.3 nM
Cc1cccc2c1nc(-c1ccccc1)n1cnnc21 CHEMBL1560355 Potency 6.3 nM
CCOc1ccc2nc(COC(=O)c3ccco3)c(C(C)=O)[n+]([O-])c2c1 CHEMBL1425970 Potency 6.3 nM
Cc1ccccc1OCc1nc(-c2ccc(-n3cccc3)cc2)no1 CHEMBL1583467 Potency 6.3 nM
CN(C)c1ccc(-c2nc(NCc3cccnc3)c3ccccc3n2)cc1 CHEMBL1474468 Potency 6.3 nM
Cc1ccc(-n2nnnc2SCC(=O)c2cc(C)n(-c3cc(C)on3)c2C)cc1 CHEMBL1377856 Potency 6.3 nM
Oc1nc2ccccc2n1CCCSc1cnc2ccccc2n1 CHEMBL1349706 Potency 6.3 nM
CC(C)C(=O)N(Cc1cc2ccccc2nc1O)C(C)(C)C CHEMBL1544244 Potency 6.3 nM
CCN1CCc2nc(N)oc2CC1 CHEMBL149616 Potency 6.3 nM
OB(O)c1ccc(Cl)s1 CHEMBL142592 Potency 6.3 nM
COc1ccc2c(c1)[C@]13CCCC[C@@H]1[C@H](C2)N(C)CC3 CHEMBL52440 Potency 6.3 nM
CC(=O)c1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1 CHEMBL1589 Potency 6.3 nM
CCOC(=O)CSc1nc(O)c2c(C)c(C(=O)O)sc2n1 CHEMBL1594750 Potency 7.9 nM
N#Cc1cccc(NC(=O)N2CC[C@@]3(CCCN(C(=O)c4cccc(F)c4)C3)C2)c1 CHEMBL1337829 Potency 7.9 nM
Cc1cn([C@H]2C[C@H](N=[N+]=[N-])[C@H](CO)O2)c(=O)[nH]c1=O CHEMBL223306 Potency 7.9 nM
CC(=O)Nc1ccc(S(=O)(=O)NCCSc2ccccn2)cc1 CHEMBL1333081 Potency 7.9 nM
O=c1cc(N2CCOCC2)[nH]c(=O)n1-c1ccc(Cl)cc1 CHEMBL1353300 Potency 7.9 nM
Nc1ccc(N)c(Cl)c1 CHEMBL1391326 Potency 7.9 nM
CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@H]1CCCCCCC(=O)O CHEMBL3348824 Potency 10.0 nM
CCCCSCc1nc2nc(Cl)c(Cl)nc2[nH]1 CHEMBL1447333 Potency 10.0 nM
CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O CHEMBL548 Potency 10.0 nM
N#CCCCl CHEMBL1451739 Potency 10.0 nM
CCOP(=S)(OCC)Oc1cc(C)nc(C(C)C)n1 CHEMBL388560 Potency 10.0 nM
ON=C1CCCCC1 CHEMBL137035 Potency 10.0 nM
Cc1onc(O)c1C[C@H](N)C(=O)O CHEMBL276815 Potency 10.0 nM
CN(C)c1ccc(N=O)cc1 CHEMBL1569493 Potency 10.0 nM
CCC(C)(C)C CHEMBL142735 Potency 10.0 nM
COC(=O)CS CHEMBL1341329 Potency 10.0 nM
CC(=O)c1cc2c(cc1NC(=O)c1cc(C)nn1-c1ccccc1)OCO2 CHEMBL1312282 Potency 10.0 nM
BrCc1ccccc1 CHEMBL1085946 Potency 10.0 nM
CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)CCc3cccc(C(F)(F)F)c3)ccc21 CHEMBL5281228 IC50 11.0 nM
CC(=O)N1CCC(C)(c2ccccc2)C2C=C(NC(=O)OC3CCCC3)C=CC21 CHEMBL3897841 IC50 12.0 nM
CCC(NC(C)C)C(O)c1ccc(O)c2[nH]c(=O)ccc12 CHEMBL160519 Potency 12.6 nM
COc1ccc(N2C(=O)C3CCCN3C2c2cc(OC)c(OC)c(OC)c2)cc1 CHEMBL1425168 Potency 12.6 nM
CCCCCCO CHEMBL14085 Potency 12.6 nM
Cc1ccc(Sc2oc(/C=N/n3cnnc3)cc2Br)cc1 CHEMBL3211966 Potency 12.6 nM
C=CC(=O)CC CHEMBL1506228 Potency 12.6 nM
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO CHEMBL384467 Potency 12.6 nM
N#Cc1nc(Cc2ccccc2)oc1N1CCN(c2cccc(Cl)c2)CC1 CHEMBL1499261 Potency 12.6 nM
C[N+](C)(C)CC=O CHEMBL1231491 Potency 12.6 nM
CC(C)(COCC1CO1)COCC1CO1 CHEMBL1587512 Potency 12.6 nM
CC(C)(C)NC[C@H](O)c1cc(Cl)c(N)c(Cl)c1 CHEMBL1396140 Potency 12.6 nM
O=C(O)CNC(=O)c1ccc(CO)o1 CHEMBL1510406 Potency 12.6 nM
CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1 CHEMBL23327 Potency 12.6 nM
CCOC(=O)N1CCN(C(=O)c2cnn3c(C)c(Cc4ccc(C)cc4)c(C)nc23)CC1 CHEMBL1602620 Potency 12.6 nM
CCCCCCCCCCCC(=O)O CHEMBL108766 Potency 12.6 nM
c1ccc2c(N3CCNCC3)cccc2c1 CHEMBL277120 Potency 15.8 nM
COc1ccccc1CNc1nc(-c2ccc(C(=O)N(C)C)cc2)nc2ccccc12 CHEMBL1318045 Potency 15.8 nM
CCCCC(CC)COC(=O)c1ccc(C(=O)OCC(CC)CCCC)c(C(=O)OCC(CC)CCCC)c1 CHEMBL1425782 Potency 15.8 nM
CCCCCCCCN CHEMBL1160509 Potency 15.8 nM
OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H](O[C@H]1[C@H](O)[C@H]2O)O[C@@H]8CO)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO CHEMBL415690 Potency 15.8 nM
COc1ccc(Cl)cc1Nc1cc(C)nc2nc(C)nn12 CHEMBL1499097 Potency 15.8 nM
N=C(N)Nc1ccc2[nH]c3c(c2c1)C[C@]1(O)[C@@H]2Cc4ccc(O)c5c4[C@]1(CCN2CC1CC1)[C@H]3O5 CHEMBL1359159 Potency 15.8 nM
COC(=O)[C@@]1(Cc2ccc(F)cc2)[C@H]2c3cc(C(=O)N4CCCC4)n(CCCNc4ncc(C(F)(F)F)cc4Cl)c3C[C@H]2CN1C(=O)c1ccccc1 CHEMBL1569485 Potency 15.8 nM
CCC(=O)Nc1c(C)cc(C)cc1Cl CHEMBL1602276 Potency 15.8 nM
COc1ccc(C2Nc3cccc(O)c3C(=O)N2Cc2ccccc2)cc1CSc1ccc(NC(C)=O)cc1 CHEMBL1715624 EC50 18.0 nM
OCc1ccccc1 CHEMBL720 Potency 20.0 nM
O=C1c2cccnc2C(=O)N1Cc1cccs1 CHEMBL1503684 Potency 20.0 nM
NC(=O)c1cnccn1 CHEMBL614 Potency 20.0 nM
Cc1cc(C)nc(NC2=NCCN2C(=O)NC2CCCCC2)n1 CHEMBL1372935 Potency 20.0 nM
COc1cccc(N2CCN(Cc3nc(N)nc(N4CCCc5ccccc54)n3)CC2)c1 CHEMBL1576495 Potency 20.0 nM
CCc1nc2oc(C(=O)c3ccccc3)c(N)c2c2c1COC(C)(C)C2 CHEMBL1519575 Potency 20.0 nM
Clc1ccc(C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 CHEMBL416898 Potency 20.0 nM
Oc1nncc2c3ccccc3n(Cc3ccccc3F)c12 CHEMBL1352262 Potency 20.0 nM
COc1ccc(Cn2nnnc2C(c2ccccc2Cl)N2CCN(C)CC2)cc1 CHEMBL1510218 Potency 20.0 nM
CCCc1nnc(SCC(=O)Nc2ccc(OCC)cc2)n1N CHEMBL1368406 Potency 20.0 nM
Cc1ccc2c(CC(=O)OC3CCOC3=O)coc2c1 CHEMBL1432517 Potency 20.0 nM
c1ccc2c(c1)[I+]c1ccccc1-2 CHEMBL365739 Potency 20.0 nM
CCn1c(=O)c(=O)[nH]c2cc(C(=O)N3CCN(c4ccccc4F)CC3)ccc21 CHEMBL1586897 Potency 20.0 nM
CC(=O)N1c2cnc(NC(=O)OCC(C)(C)C)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5275472 IC50 24.0 nM
Cc1ccccc1-c1cncnc1NCc1ccccc1 CHEMBL450493 Potency 25.1 nM
O=C1CSC(=O)N1CC(O)COc1ccc(Cl)cc1 CHEMBL1344102 Potency 25.1 nM
O=C(O)CCCC(=O)N1CCN(c2cccc(Cl)c2)CC1 CHEMBL1605515 Potency 25.1 nM
C[S@](=N)(=O)CC[C@@H](N)C(=O)O CHEMBL1552247 Potency 25.1 nM
CCOC(=O)C1=C(c2ccccc2)NC(SCC(=O)Nc2ccc(C)cc2)=C(C#N)C1c1ccco1 CHEMBL409906 Potency 25.1 nM
Oc1cccc(Cl)c1Cl CHEMBL16656 Potency 25.1 nM
Cn1cc(-c2nc3cnc(Oc4cccc(Cl)c4)nc3n(CCC#N)c2=O)c2ccccc21 CHEMBL1404884 Potency 25.1 nM
CN1CCN(c2ccc(NC(=O)c3ccccc3Br)cc2)CC1 CHEMBL1562638 Potency 25.1 nM
O=C(C1CCCO1)N1CCN(c2ncccn2)CC1 CHEMBL1445003 Potency 25.1 nM
CN1C(=O)CC[C@@H]1c1cccnc1 CHEMBL365343 Potency 25.1 nM
C[C@@]12CC[C@H]3[C@@H](CC[C@]4(O)C[C@H](O)CC[C@@]34C=O)[C@]1(O)CC[C@@H]2C1=CC(=O)OC1 CHEMBL1437139 Potency 25.1 nM
COC1(OC)N=C(N)C2(C#N)C(c3ccc(F)cc3)C12C#N CHEMBL1576798 Potency 25.1 nM
O=C(NCc1ccco1)C1(c2ccccc2)CCCC1 CHEMBL1518808 Potency 25.1 nM
N#Cc1ccccc1OCC(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2 CHEMBL1411000 Potency 25.1 nM
CSc1cccc(NC(=O)C2CCN(S(C)(=O)=O)CC2)c1 CHEMBL1400094 Potency 25.1 nM
COc1ccc(CNc2ncnc3ccc(-c4ccccc4OC)cc23)c(OC)c1 CHEMBL490706 Potency 25.1 nM
CN=C=O CHEMBL1608558 Potency 25.1 nM
COCC(=O)N(Cc1nc(O)c2ccccc2n1)Cc1cccs1 CHEMBL1510902 Potency 25.1 nM
COc1ccccc1Oc1coc2cc(OC(=O)N3CCOCC3)ccc2c1=O CHEMBL1491679 Potency 25.1 nM
Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl CHEMBL1369208 Potency 25.1 nM
CC1=CC(=O)CC(C)(C)C1(O)/C=C/C(C)=C\C(=O)O CHEMBL379808 Potency 31.6 nM
Cc1ccc2nc(NC(=O)CN(C)S(=O)(=O)c3cccc4nsnc34)sc2c1 CHEMBL1423574 Potency 31.6 nM
O=S(=O)(c1cccc2ncccc12)N1CCNCC1 CHEMBL1330500 Potency 31.6 nM
COc1ccc(Oc2ncc3nc(-c4ccccc4)c(=O)n(C4CC4)c3n2)cc1 CHEMBL1590974 Potency 31.6 nM
COc1ccc(-c2noc(CCC(=O)NCCN(C)Cc3ccccc3)n2)cc1 CHEMBL1375233 Potency 31.6 nM
Cc1ccc2ccccc2c1C CHEMBL382541 Potency 31.6 nM
Cc1cc(N)c2ccccc2[n+]1CCCCCCCCCCCCCC[n+]1c(C)cc(N)c2ccccc21 CHEMBL1257056 Potency 31.6 nM
CN1[C@@H]2CC[C@H]1CC(NC(=O)c1nn(C)c3ccccc13)C2 CHEMBL1315374 Potency 31.6 nM
CCNc1ncc2ncc(=O)n(CCc3ccccc3)c2n1 CHEMBL1572173 Potency 31.6 nM
COc1ccc(C(c2nnnn2C2CCCCC2)N2CCN(c3ccccc3F)CC2)cc1 CHEMBL1528551 Potency 31.6 nM
COc1ccc(CNC(=O)c2ccc(CN3CCOCC3)cc2)cc1 CHEMBL1454670 Potency 31.6 nM
CS(=O)(=O)N1CCC[C@@]2(CCN(Cc3ccccc3)C2)C1 CHEMBL1324151 Potency 31.6 nM
COc1cccc(OC)c1OCCNC[C@@H]1COc2ccccc2O1 CHEMBL36622 Potency 31.6 nM
c1ccc(Cn2nnc3c(N4CCCC4)ncnc32)cc1 CHEMBL1584572 Potency 31.6 nM
CCc1nccn1S(=O)(=O)c1ccc2ccc(C)cc2c1 CHEMBL1336766 Potency 31.6 nM
CCNS(=O)(=O)c1ccc(NC(=O)Nc2cccc(OC)c2)cc1 CHEMBL1583283 Potency 31.6 nM
CCCCCCCC/C=C\CCCCCCCC(=O)N(CCO)CCO CHEMBL15712 Potency 31.6 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2 CHEMBL407 Potency 31.6 nM
COc1ccccc1CNC(=O)CSc1nc2nc(C)cc(C)n2n1 CHEMBL1347066 Potency 31.6 nM
COc1ncc2nc(-c3cn(C)c4ccccc34)c(=O)n(-c3ccccc3)c2n1 CHEMBL1455462 Potency 31.6 nM
Nc1nc2c(nc(Br)n2[C@@H]2O[C@H]3COP(=O)([O-])O[C@@H]3[C@H]2O)c(=O)[nH]1 CHEMBL1395654 Potency 31.6 nM
COC(=O)c1ccccc1NC(=O)CN(CCc1ccccc1)S(C)(=O)=O CHEMBL1477929 Potency 31.6 nM
CCn1c(SCC(=O)N2CCC(C(N)=O)(N3CCCCC3)CC2)nc2ccccc2c1=O CHEMBL1451198 Potency 31.6 nM
CCOC(=O)C1CCN(S(=O)(=O)Cc2ccc(Cl)cc2)CC1 CHEMBL1607385 Potency 31.6 nM
CCC(C)Sc1nc(O)cc(O)n1 CHEMBL1380581 Potency 31.6 nM
CCC(Sc1nc(O)c2cnn(-c3ccc(Cl)cc3)c2n1)C(=O)OC CHEMBL1421873 Potency 31.6 nM
CC1(C)CC(CCNC(=O)c2ccco2)CC(C)(C)N1 CHEMBL1527174 Potency 31.6 nM
Cc1cc(C)nc(N2CCC(C(=O)NCc3cccc(C(F)(F)F)c3)CC2)n1 CHEMBL1369719 Potency 31.6 nM
CCO CHEMBL545 Potency 31.6 nM
CCOC(=O)c1c(NC(=O)c2nn(CC)cc2Br)c(C#N)nn1-c1ccccc1 CHEMBL1539531 Potency 31.6 nM
NCCC[C@@H](CC(=O)N[C@@H]1CCCC[C@H]1C(=O)N[C@H](CC(=O)N[C@@H](CCC(=O)O)CC(=O)O)Cc1ccccc1)NC(=O)C[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCC[C@H]1N CHEMBL1440362 Potency 31.6 nM
CCOc1cc(CN2CCSCC2)ccc1O CHEMBL1412889 Potency 31.6 nM
CCCCC(C=O)CC CHEMBL1558074 Potency 31.6 nM
COc1ccc(CCN(C)CCC[C@@](C#N)(c2cc(OC)c(OC)c(OC)c2)C(C)C)cc1OC CHEMBL1401296 Potency 31.6 nM
COC(=O)c1ccccc1NC(=O)NCc1ccc2c(c1)OCO2 CHEMBL1411249 Potency 31.6 nM
N=C(N)NCCSSCCNC(=N)N CHEMBL105278 Potency 31.6 nM
CN(C)C(=O)NCc1ccc(S(N)(=O)=O)cc1 CHEMBL1568097 Potency 31.6 nM
COc1ccc(N2CCN(Cc3nc(O)c4ccccc4n3)CC2)cc1 CHEMBL1565591 Potency 31.6 nM
O=C(Nc1nccs1)c1ccc(S(=O)(=O)N2CCCCC2)cc1 CHEMBL1595887 Potency 31.6 nM
CCOC(=O)c1oc2cccc(O)c2c1CN(Cc1ccccc1)C(C)=O CHEMBL1331935 Potency 31.6 nM
CCOc1cc(C(N)=O)cc(OCC)c1OCC CHEMBL1604796 Potency 31.6 nM
CC[C@H](C)[C@@H]1O[C@]2(CC[C@@H]1C)C[C@H]1C[C@H](C/C=C(\C)[C@@H](O[C@H]3C[C@H](OC)[C@H](O[C@H]4C[C@H](OC)[C@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)/C=C/C=C3CO[C@@H]4[C@@H](O)C(C)=C[C@H](C(=O)O1)[C@@]34O)O2 CHEMBL1399099 Potency 31.6 nM
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2O CHEMBL386630 Potency 31.6 nM
CCn1c2ccccc2c2cc(CN3CCN(C(=O)c4ccco4)CC3)ccc21 CHEMBL1339050 Potency 31.6 nM
CC(=O)NCCOc1nc(N(C)C)nc(N2CCOCC2)n1 CHEMBL1613622 Potency 31.6 nM
Cc1c(NC(=O)c2ccc(COc3ccc4ccccc4c3)o2)c(=O)n(-c2ccccc2)n1C CHEMBL1413909 Potency 31.6 nM
Cc1cc(C)n(-c2ccc(OCC(=O)O)nn2)n1 CHEMBL1313315 Potency 31.6 nM
CC(C)Oc1ccc(C2CNC(=O)C2)cc1 CHEMBL1406901 Potency 31.6 nM
CCSc1nnc(NC(=O)C2CCCCC2)s1 CHEMBL1491373 Potency 31.6 nM
C=CCn1c(S)nnc1-c1cc(OC)c(OC)c(OC)c1 CHEMBL1373631 Potency 31.6 nM
NC(=O)c1nsc(C(=O)N(CC(=O)NC2CCCCC2)Cc2ccc3c(c2)OCO3)c1N CHEMBL1555290 Potency 31.6 nM
CC(=O)N1c2cnc(NC(=O)OCC3(C(F)(F)F)CC3)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5267043 IC50 33.0 nM
CC(=O)N1c2cnc(NC(=O)CCc3cccc(Cl)c3)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5287707 IC50 35.0 nM
O=C(Cn1cccc1C(=O)c1ccccc1)NCc1ccc2c(c1)OCO2 CHEMBL1300290 Potency 39.8 nM
COc1ccc(S(=O)(=O)NCCC(=O)NCc2ccc(F)cc2)cc1 CHEMBL1452905 Potency 39.8 nM
Cc1cnc(CNc2ncnc3ccc(-c4c(C)noc4C)cc23)cn1 CHEMBL1322584 Potency 39.8 nM
CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@](C(=O)OC)(c3cc4c(cc3OC)N(C)[C@@H]3[C@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1 CHEMBL1315323 Potency 39.8 nM
O=C(c1cc(-c2cccs2)on1)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1502745 Potency 39.8 nM
Cc1cc2nnc(SC3CCOC3=O)n2c2ccccc12 CHEMBL1598997 Potency 39.8 nM
CN(C)c1cccc(O)c1 CHEMBL225257 Potency 39.8 nM
CN(C)CCCN1c2ccccc2Sc2ccccc21 CHEMBL564 Potency 39.8 nM
Cc1csc2nc(CCNS(=O)(=O)c3ccc4c(c3)OCCO4)cn12 CHEMBL1324414 Potency 39.8 nM
CC(C)NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL2062275 Potency 39.8 nM
O=C(O)CP(=O)(O)O CHEMBL50300 Potency 39.8 nM
O=C(CSc1nnc(-c2ccc(Br)cc2)o1)Nc1cccc2ccccc12 CHEMBL1505070 Potency 39.8 nM
COc1ccc(-c2cc(C(=O)N3CCN(C(c4ccccc4)c4ccccc4)CC3)no2)cc1OC CHEMBL1605525 Potency 39.8 nM
CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)[C@H]1c1cccc([N+](=O)[O-])c1 CHEMBL268609 Potency 39.8 nM
CN(C)c1ccc(NC(=O)Cn2cc3c(n2)CCCC3)cc1 CHEMBL1342384 Potency 39.8 nM
CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)COC(=O)c1cccs1 CHEMBL1498604 Potency 39.8 nM
COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@@H]1c1cccc([N+](=O)[O-])c1 CHEMBL1514440 Potency 39.8 nM
CC(C)C[C@@H](CC(=O)N[C@@H](CCCN)CC(=O)N[C@@H]1CCCC[C@H]1C(=O)N[C@H](CC(=O)N[C@@H](CCC(=O)O)CC(=O)O)Cc1ccccc1)NC(=O)[C@@H]1CNCC[C@H]1N CHEMBL1512602 Potency 39.8 nM
CCOC(=O)c1cc2sc(C)cc2n1CC(=O)NCCc1ccccc1 CHEMBL1595916 Potency 39.8 nM
O=C(C1CCN(c2nnc(N3CCCC3=O)s2)CC1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 CHEMBL1329718 Potency 39.8 nM
COCCN(CCOC)S(=O)(=O)c1ccc(C(=O)Nc2nc(-c3ccncc3)cs2)cc1 CHEMBL1431278 Potency 39.8 nM
NC(=O)Nc1cc([As](=O)(O)O)cc(I)c1O CHEMBL1525237 Potency 39.8 nM
Cc1cnc(CNc2cc(-c3ccccc3C(F)(F)F)ncn2)cn1 CHEMBL1590059 Potency 39.8 nM
CN(C)C=O CHEMBL268291 Potency 39.8 nM
O=C1NC(=O)C(c2ccccc2[N+](=O)[O-])=C1Nc1ccc(O)c(Cl)c1 CHEMBL322970 Potency 39.8 nM
COc1ccc(Br)cc1CNC(=O)C1CCC(=O)N1C(C)C CHEMBL1413998 Potency 39.8 nM
CC1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 CHEMBL1563733 Potency 39.8 nM
CC(=O)N1c2ccc(NC(=O)OCc3cccc(Cl)c3)cc2C2(CCCCC2)C1(C)C CHEMBL5267166 IC50 42.0 nM
CC(=O)N1c2cnc(NC(=O)OCC(C)C)nc2C2(CCCCC2)C1(C)C CHEMBL5288869 IC50 45.0 nM
CC(=O)N1c2cnc(NC(=O)OCc3ccccc3)nc2C2(CCCCC2)C1(C)C CHEMBL5270266 IC50 46.0 nM
CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)OCc3ccc(F)c(Cl)c3)ccc21 CHEMBL3979710 IC50 47.0 nM
CC(=O)N1c2cnc(NC(=O)O[C@H](C)C(C)(C)C)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5286556 IC50 48.0 nM
CC(=O)N1c2cnc(NC(=O)OCC(C)(C)C)nc2C2(CCCCC2)C1(C)C CHEMBL5275619 IC50 49.0 nM
COCCn1c(=O)c(-c2ccc(F)cc2)nc2cnc(Oc3ccccc3)nc21 CHEMBL1592506 Potency 50.1 nM
C[C@](O)(c1ccccc1)c1nccc2ccccc12 CHEMBL1322979 Potency 50.1 nM
CCC(C)(C)NC(=O)CN(C(=O)c1snc(C(N)=O)c1N)c1ccc2c(c1)OCO2 CHEMBL1402689 Potency 50.1 nM
CCN(CC)N=O CHEMBL164290 Potency 50.1 nM
CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1 CHEMBL343633 Potency 50.1 nM
CCOC(=O)c1c(C)c(C(=O)NCCCN2CCCC2=O)c(C)n1CC CHEMBL1444033 Potency 50.1 nM
CC(=O)Oc1ccccc1C(=O)O CHEMBL25 Potency 50.1 nM
CC(C)(Oc1ccc([C@@H]2CC2(Cl)Cl)cc1)C(=O)O CHEMBL1317234 Potency 50.1 nM
Cc1cc(NC(=O)CSc2nnc(CNc3cccc(C(F)(F)F)c3)n2Cc2ccco2)no1 CHEMBL1607988 Potency 50.1 nM
CC(=O)N1c2cnc(NC(=O)OCc3cccc(Cl)c3)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5270771 IC50 56.0 nM
CC(=O)N1c2cnc(NC(=O)OCc3cccc(Cl)c3)nc2C2(CCCCC2)C1(C)C CHEMBL5285685 IC50 58.0 nM
CC(=O)N1c2cnc(NC(=O)O[C@@H](C)C(C)(C)C)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5290721 IC50 62.0 nM
CC/C=C/C/C=C/C/C=C/CCCCCCCC(=O)OCC CHEMBL1527567 Potency 63.1 nM
COc1ccc(C(=O)N2CCC3(CCCN(Cc4ccc(C#N)cc4)C3)CC2)cc1 CHEMBL1315521 Potency 63.1 nM
CN1CCN(C(=O)Cc2nc3ccccc3[nH]2)CC1 CHEMBL1465767 Potency 63.1 nM
CCCCn1cnc2c(SC)ncnc21 CHEMBL1364705 Potency 63.1 nM
CC(COc1ccccc1)N(CCCl)Cc1ccccc1 CHEMBL1200787 Potency 63.1 nM
Cc1ccc([N+](=O)[O-])cc1N CHEMBL324642 Potency 63.1 nM
Cn1cnc(S(=O)(=O)N2CCc3ccccc32)c1 CHEMBL1578595 Potency 63.1 nM
Cc1cc(O)nc(SCc2cccc(Br)c2)n1 CHEMBL1339447 Potency 63.1 nM
CC(C)NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1160723 Potency 63.1 nM
CC(=O)N1c2cnc(NC(=O)OCC3(C(F)(F)F)CC3)nc2C2(CCCCC2)C1(C)C CHEMBL5283477 IC50 65.0 nM
CC(=O)N1c2ccc(NC(=O)OCC(C)(C)C)cc2C2(CCCCC2)C1(C)C CHEMBL5271120 IC50 71.0 nM
CC(=O)N1c2cnc(NC(=O)CCc3cccc(Cl)c3)nc2C2(CCCCC2)C1(C)C CHEMBL5279687 IC50 72.0 nM
CC(=O)N1c2ccc(NC(=O)OCC(C)(C)C)nc2C2(CCCCC2)C1(C)C CHEMBL5288635 IC50 74.0 nM
C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@@]3(C)[C@@H](O)CCC(C)(C)[C@@H]3[C@H](O)[C@H](OC(C)=O)[C@@]2(C)O1 CHEMBL1473060 Potency 79.4 nM
CCN(CC)S(=O)(=O)c1cccc(-c2nnc(SCC(=O)NC)n2CCc2ccccc2)c1 CHEMBL1538849 Potency 79.4 nM
OC1CCCC1 CHEMBL288998 Potency 79.4 nM
COc1ccc(N2C(=O)NC(=O)/C(=C\NC3CC3)C2=O)cc1 CHEMBL1502097 Potency 79.4 nM
CCCCC(CC)COC(=O)CCCCC(=O)OCC(CC)CCCC CHEMBL1414950 Potency 79.4 nM
OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)C(Cl)(Cl)Cl CHEMBL228511 Potency 79.4 nM
COCCn1c(=O)c(-c2ccc(OC)cc2)nc2cnc(N3CCNCC3)nc21 CHEMBL1317498 Potency 79.4 nM
O=C(COc1ccccc1O)Nc1ccccc1Cl CHEMBL1520432 Potency 79.4 nM
C=C(C)C1CC=C(C)C(O)C1 CHEMBL1385229 Potency 79.4 nM
CC(C)OCCCNC(=O)c1c(N)n(CC2CCCO2)c2nc3ccccc3nc12 CHEMBL1419900 Potency 79.4 nM
Clc1ccc(C(Cl)(Cl)Cl)cc1Cl CHEMBL1567313 Potency 79.4 nM
CCOC(=O)CC(SP(=O)(OC)OC)C(=O)OCC CHEMBL1331476 Potency 79.4 nM
CCOc1ccc(-c2nc(CSCC(=O)N3CCN(C(=O)c4ccco4)CC3)c(C)o2)cc1 CHEMBL1461535 Potency 79.4 nM
COC(=O)c1cc2sccc2n1CC(=O)N1CCCc2ccccc21 CHEMBL1419263 Potency 79.4 nM
CCNC(=O)[C@@H]1O[C@@H](n2cnc3c(N)nc(NCCc4ccc(CCC(=O)O)cc4)nc32)[C@H](O)[C@@H]1O CHEMBL1490326 Potency 79.4 nM
COc1cccc(C2=NOC(C(=O)Nc3cccc(C(C)=O)c3)C2)c1OC CHEMBL1525418 Potency 79.4 nM
O=C(CSc1nnc(-c2cccs2)n1-c1ccccc1)N1CCN(C(=O)c2ccco2)CC1 CHEMBL1508186 Potency 79.4 nM
CC(C)C(=O)N(c1ccc(F)cc1)C1C=CS(=O)(=O)C1 CHEMBL1350377 Potency 79.4 nM
Cn1c(=O)c2c(ncn2CC(=O)N2CCN(c3ccccc3F)CC2)n(C)c1=O CHEMBL1469177 Potency 79.4 nM
COc1ccc(CCN2C(=O)CC(N3CCN(S(=O)(=O)c4ccccc4)CC3)C2=O)cc1 CHEMBL1570558 Potency 79.4 nM
N[C@H](CCCC(=O)O)C(=O)O CHEMBL1169505 Potency 79.4 nM
COc1ccc(C2Nc3ccccc3C(=O)N2Cc2ccccc2)cc1CSc1ccc(NC(C)=O)cc1 CHEMBL1719708 EC50 80.0 nM
CC(=O)N1c2cnc(NC(=O)OCc3ccccc3)cc2C2(CCCCC2)C1(C)C CHEMBL5285769 IC50 82.0 nM
CC(=O)N1c2cnc(NC(=O)OCC(C)C)cc2C2(CCCCC2)C1(C)C CHEMBL5285143 IC50 82.0 nM
CC(=O)N1c2cnc(NC(=O)OC(C)(C)C)nc2C2(CCC(F)(F)CC2)C1(C)C CHEMBL5268829 IC50 85.0 nM
CC(=O)N1c2ccc(C(N)=O)cc2C(C)(c2ccccc2)CC1(C)C CHEMBL3891546 IC50 88.0 nM
COc1ccc(C2Nc3cccc(O)c3C(=O)N2Cc2ccccc2)cc1COc1ccc(NC(C)=O)cc1 CHEMBL1515891 EC50 90.0 nM
CC(=O)N1c2ncc(NC(=O)OCC(C)(C)C)cc2C2(CCCCC2)C1(C)C CHEMBL5268512 IC50 91.0 nM