CCCN(CCC)C(=O)Cc1c(-c2ccc([N+](=O)[O-])cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL520465 Ki 0.15 nM
COc1ccc(OC)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1 CHEMBL63064 Ki 0.188 nM
COc1ccc(O[11CH3])c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1 CHEMBL401000 Ki 0.242 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(OCC[18F])cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL5428961 Ki 0.27 nM
COc1ccc(-c2ccc3oc(=O)n(CC(=O)N(C)c4ccccc4)c3c2)cc1 CHEMBL2088374 Ki 0.28 nM
COc1ccc(OC)c(CC(C(=O)C[18F])c2ccccc2Oc2ccccc2)c1 CHEMBL5275028 Ki 0.3 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL432608 Ki 0.41 nM
CCN(CC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(C)cc(C)nn12 CHEMBL3659631 Ki 0.45 nM
CCN(CC)C(=O)Cc1c(-c2ccc(C)cc2)nc2c(C)cc(C)nn12 CHEMBL3659630 Ki 0.46 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12 CHEMBL54349 Ki 0.5 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(OC)cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL509917 Ki 0.537 nM
CCC(C)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1 CHEMBL481537 Activity 0.63 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(NC(=O)CCC(=O)OCC)cccn12 CHEMBL483596 Ki 0.86 nM
CCN(CC)C(=O)[C@H]1CCCc2c1c1ccccc1n2CCF CHEMBL3408974 Ki 0.87 nM
CCCCN(C)C(=O)Cc1c(-c2ccc(OC)cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL521186 Ki 0.882 nM
CC(=O)N(Cc1ccccc1OC(C)C)c1ccc(Cl)cc1Oc1ccccc1 CHEMBL205767 IC50 0.92 nM
CCN(CC)C(=O)Cc1c(-c2ccc(Br)cc2)nc2c(C)cc(C)nn12 CHEMBL3659632 Ki 0.97 nM
COc1ccc(OC)c(CN(C(=O)CF)c2ccccc2Oc2ccccc2)c1 CHEMBL473435 Ki 0.997 nM
COc1ccccc1CN(C(=O)C[18F])c1cnccc1Oc1ccccc1 CHEMBL5418378 Ki 0.997 nM
CN1C(=O)CN=C(c2ccc(Cl)cc2)c2cc(Cl)ccc21 CHEMBL286346 Kd 1.1 nM
COc1ccccc1CN(C(C)=O)c1cnc(F)cc1Oc1ccccc1 CHEMBL1817978 Ki 1.19 nM
CC(=O)N(Cc1ccccc1C(=O)O[11CH3])c1ccccc1Oc1ccccc1 CHEMBL253596 Ki 1.4 nM
CCN(CC)C(=O)Cc1c(-c2ccc(OCCF)cc2)nc2c(C)cc(C)nn12 CHEMBL3659635 Ki 1.55 nM
CCCN(CCC)C(=O)C(=O)c1c(-c2ccc([N+](=O)[O-])cc2)n(C)c2ccccc12 CHEMBL1651236 Ki 1.57 nM
COc1ccc(OC)c(CN(C(C)=O)c2ccc(F)cc2Oc2ccccc2)c1 CHEMBL3970955 IC50 1.6 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(N)cccn12 CHEMBL339816 Ki 1.6 nM
CC[C@@H](C)N([11CH3])C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1 CHEMBL2206280 Kd 2.0 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(CC(=O)CCCCC(=O)Nc3ccn([C@@H]4O[C@H](CO)[C@@H](O)[C@@H]4O)c(=O)n3)cccn12 CHEMBL4456416 IC50 2.13 nM
CC(=O)N(Cc1ccccc1O[11CH3])c1cnccc1Oc1ccccc1 CHEMBL253597 Ki 2.2 nM
CCN(CC)C(=O)Cc1c(-c2ccc(F)cc2)nc2c(C)cc(C)nn12 CHEMBL3659633 Ki 2.4 nM
CCN(CC)C(=O)[C@H]1CCCc2c1c1c(OC)cccc1n2CC[18F] CHEMBL1944785 Ki 2.4 nM
COc1ccccc1CN(C(C)=O)c1cnccc1Oc1ccccc1 CHEMBL2068817 Ki 2.5 nM
CCN(CC)C(=O)Cc1c(-c2ccc(OC)cc2)nc2c(C)cc(C)nn12 CHEMBL3659629 Ki 2.61 nM
CCCCN(CCCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL180523 Ki 2.68 nM
COc1ccc(-c2ccc3c(c2)c2ccccc2n3CC(=O)N(C)Cc2cccc(OC)c2)cc1 CHEMBL4459176 Ki 3.2 nM
CCCCCCN(CCCCCC)C(=O)Cc1c(-c2ccc(F)cc2)[nH]c2ccccc12 CHEMBL63154 Ki 3.25 nM
CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2C CHEMBL517539 Kd 3.5 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12 CHEMBL97269 Ki 3.9 nM
Cc1ccc(CN(C)C(=O)c2nc(-c3ccccc3Cl)c3ccccc3n2)cc1 CHEMBL5187502 Ki 3.99 nM
CCN(CC)C(=O)C(Oc1cccnc1-n1cccc1)c1ccc(OC)cc1 CHEMBL3659636 Ki 4.0 nM
CC[C@H](C)N([11CH3])C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1 CHEMBL251953 Ki 4.5 nM
CCN(CC)C(=O)C(Oc1ccccc1-n1cccc1)c1ccc(OC)cc1 CHEMBL3659637 Ki 5.0 nM
CCN(CC)C(=O)C(Oc1ccc(Cl)cc1-n1cccc1)c1ccc(OC)cc1 CHEMBL3659638 Ki 5.7 nM
CCN(Cc1ccccc1)C(=O)Cc1c(-c2ccc(OC)cc2)nn2c(C)cc(C)nc12 CHEMBL4789235 Ki 6.2 nM
CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(C)c2cnc(-c3ccccc3)nc21 CHEMBL513922 Ki 6.4 nM
CCN(CC)C(=O)Cc1c(-c2ccc(OC)cc2)nn2c(C)cc(C)nc12 CHEMBL480041 Ki 6.68 nM
CC(=O)N(C)c1ccccc1Oc1ccccc1 CHEMBL5179737 IC50 6.7 nM
CN(C(=O)Cn1c(=O)oc2ccc(-c3cccnc3)cc21)c1ccc(C(F)(F)F)cc1 CHEMBL2442940 Ki 8.0 nM
CC(=O)N(Cc1ccccc1OC[18F])c1cnccc1Oc1ccccc1 CHEMBL5199978 IC50 8.28 nM
COc1ccc(-c2nn3c(C)cc(C)nc3c2CC(=O)N(C)Cc2ccccc2)cc1 CHEMBL4742003 Ki 9.3 nM
CCC(C)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2[123I])n1 CHEMBL5277709 Kd 10.0 nM
CCN(CC)C(=O)Cc1c(-c2ccc(O)cc2)nc2c(C)cc(C)nn12 CHEMBL3659634 Ki 10.96 nM
CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc([N+](=O)[O-])cn12 CHEMBL106237 IC50 11.8 nM
CC[C@@H](C)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1 CHEMBL416715 Ki 13.6 nM
CCN(Cc1ccccc1)C(=O)CN1c2ccccc2NC(=O)c2ccccc21 CHEMBL4742171 Ki 15.8 nM
CCN(CC)C(=O)Cn1c2ccccc2c2cc(-c3ccccc3OC)ccc21 CHEMBL4165898 Ki 25.4 nM
CCN(CC)C(=O)Cn1c(-c2ccc(OC)cc2)cc2c(C)cc(C)cc21 CHEMBL3634876 Ki 28.13 nM
CCN(CC)C(=O)Cn1c2ccccc2c2cc(-c3ccc(OC)cc3)ccc21 CHEMBL4173816 Ki 28.9 nM
CCN(CC)C(=O)Cn1c(-c2ccc(OC)cc2)nc2c(C)cc(C)nc21 CHEMBL3634878 Ki 29.11 nM
CCN(CC)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4173118 Ki 30.1 nM
CCN(CC)C(=O)Cn1c2ccccc2c2cc(Br)ccc21 CHEMBL4164932 Ki 31.5 nM
CCN(CC)C(=O)Cn1c2ccccc2c2cc(-c3ccccc3)ccc21 CHEMBL4177167 Ki 31.6 nM
CCc1nnc(SCC(=O)N(C)c2ccccc2)c2cc3sccc3n12 CHEMBL1315992 Kd 39.6 nM
C=Cc1c(C)c2cc3nc(c4c5[nH]c(cc6nc(cc1[nH]2)C(C)=C6CC)c(C)c5C(=O)C4)[C@@H](CCC(=O)NCCCCCCNC(=O)c1cc2ccccc2c(-c2ccccc2I)n1)[C@@H]3C CHEMBL1672413 Kd 40.0 nM
CN(Cc1ccccc1)C(=O)CN1Cc2cnn(C)c2Nc2ccccc21 CHEMBL4758934 Ki 41.3 nM
CCN(Cc1ccccc1)C(=O)CN1Cc2cnn(C)c2Nc2ccccc21 CHEMBL4745926 Ki 41.3 nM
O[C@@H]1[C@H](O)[C@@H]2C[C@@H]2[C@H]1n1cnc2c(NCCc3cccc(Cl)c3)nc(C#Cc3ccc(Cl)s3)nc21 CHEMBL4537118 Ki 50.0 nM
CN(Cc1ccccc1)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4447335 Ki 53.0 nM
CCN(Cc1ccccc1)C(=O)Cn1c2ccccc2c2cc(Br)ccc21 CHEMBL4169328 Ki 54.3 nM
CCc1nnc(SCC(=O)N(C)c2ccccc2)c2cc3sc(C)cc3n12 CHEMBL4174207 Kd 61.2 nM
CCN(Cc1ccccc1)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4161842 Ki 70.0 nM
CCOc1ccc(F)cc1NC(=O)c1cc(F)ccc1NS(=O)(=O)C1CC1 CHEMBL5195160 Ki 71.0 nM
CN(Cc1ccccc1)C(=O)CN1c2ccccc2NC(=O)c2ccccc21 CHEMBL4743573 Ki 76.8 nM
CCN(Cc1cccc(OC)c1)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4439049 Ki 96.1 nM
Cc1ccc(C(C)C)cc1NC(=O)Cn1c(Cc2c(Cl)cccc2Cl)nc2ccccc21 CHEMBL3948914 Kd 108.0 nM
CCOC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(N=C=S)cc12 CHEMBL5179024 Ki 108.0 nM
CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 CHEMBL3716980 Ki 111.12 nM
CCCC(CCC)c1nc2c(Nc3ccc(I)cc3)nc3ccccc3c2[nH]1 CHEMBL5170790 Ki 123.0 nM
CCCCN(CCCC)C(=O)CN1C[C@@H](c2ccc3c(c2)OCO3)[C@H](C(=O)O)[C@H]1c1ccc(OC)cc1 CHEMBL428504 Ki 183.97 nM
CCN(Cc1ccccc1F)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4466212 Ki 184.2 nM
O[C@@H]1[C@H](O)[C@@H]2C[C@@H]2[C@H]1n1cnc2c(NCCc3cccc(F)c3)nc(C#Cc3ccc(Cl)s3)nc21 CHEMBL4519265 Ki 200.0 nM
CCN(CC)C(=O)CN1c2ccccc2NC(=O)c2ccccc21 CHEMBL4793373 Ki 200.5 nM
COc1cccc(CN(C)C(=O)Cn2c3ccccc3c3cc(-c4cccc(Cl)c4)ccc32)c1 CHEMBL4535242 Ki 200.7 nM
CC(C)C[C@H](NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)O CHEMBL5169788 Ki 202.0 nM
CCN(CC)C(=O)Cn1c(-c2ccc(OC)cc2)nc2c(C)cc(C)cc21 CHEMBL3634877 Ki 207.6 nM
COc1cccc(CN(C)C(=O)Cn2c3ccccc3c3cc(-c4ccccc4)ccc32)c1 CHEMBL4560218 Ki 208.4 nM
C=Cc1c(C)c2cc3nc(c4c5[nH]c(cc6nc(cc1[nH]2)C(C)=C6CC)c(C)c5C(=O)C4)[C@@H](CCC(=O)N(C)CCCCCCN(C)C(=O)c1cc2ccccc2c(-c2ccccc2I)n1)[C@@H]3C CHEMBL1672415 IC50 210.0 nM
COc1cccc(CN(C)C(=O)Cn2c3ccccc3c3cc(-c4ccccc4Cl)ccc32)c1 CHEMBL4563441 Ki 214.0 nM
CCN(Cc1ccccc1NC(C)=O)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4440106 Ki 243.0 nM
CCOc1ccc(F)cc1NC(=O)c1ccccc1NS(=O)(=O)C1CC1 CHEMBL5172913 Ki 271.0 nM
CC(=O)N(Cc1ccc(OCCF)cc1)c1cc(C)cc(C)c1 CHEMBL4744362 Ki 275.0 nM
CC(=O)N(Cc1ccccc1)c1cc(C)cc(C)c1 CHEMBL4750553 Ki 275.5 nM
CS(=O)(=O)c1cc(F)cc2c3c(n(Cc4ccc(Cl)cc4)c12)[C@@H](CC(=O)O)CC3 CHEMBL426559 Ki 286.42 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(NC(=O)CN(Cc3ccccn3)Cc3ccccn3)cccn12 CHEMBL3287610 Ki 293.0 nM
COc1ccc(-c2nn3c(C)cc(C)nc3c2CC(=O)N(C)C)cc1 CHEMBL4753783 Ki 337.9 nM
COc1cccc(NC[C@H](F)Cn2c3ccc(Br)cc3c3cc(Br)ccc32)n1 CHEMBL3265238 IC50 350.0 nM
CCN(Cc1cccc(OC)c1)C(=O)Cn1c2ccccc2c2cc(-c3ccc(OC)cc3)ccc21 CHEMBL4532562 Ki 369.0 nM
CC(=O)N(Cc1ccc(OCc2ccccc2)cc1)c1cc(C)cc(C)c1 CHEMBL4777292 Ki 376.8 nM
CCN(Cc1cccc(OC)c1)C(=O)Cn1c2ccccc2c2cc(-c3ccccc3)ccc21 CHEMBL4461372 Ki 385.3 nM
COC(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 CHEMBL3769755 IC50 400.0 nM
Ic1ccc(Nc2nc3ccccc3c3[nH]c(C4CCCCC4)nc23)cc1 CHEMBL5195535 Ki 427.0 nM
CCN(CC)C(=O)CN(Cc1ccc(OCc2ccccc2)cc1)c1cc(C)cc(C)c1 CHEMBL4759879 Ki 433.2 nM
CCOC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12 CHEMBL5172740 Ki 438.0 nM
CCN(Cc1cccc(OC)c1)C(=O)Cn1c2ccccc2c2cc(Br)ccc21 CHEMBL4475609 Ki 462.3 nM
CCN(CC)C(=O)CN1Cc2cnn(C)c2Nc2ccccc21 CHEMBL4750743 Ki 493.0 nM
COc1ccc(CN(C(C)=O)c2cc(C)cc(C)c2)cc1 CHEMBL4756968 Ki 500.3 nM
CC(=O)N1CCC(c2ccc(-c3cc(C(=O)O)cc4cc(-c5ccc(C(F)(F)F)cc5)ccc34)cc2)CC1 CHEMBL4642592 Ki 508.0 nM
Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4cccc(O)c4)cc3c2OCCCN)c1 CHEMBL1766103 Ki 522.4 nM
CC(C)(C)Cc1c(C#Cc2ccccc2F)sc(N)c1C(=O)c1ccc(Cl)cc1 CHEMBL5422582 Ki 560.0 nM
CCN(Cc1cccc(F)c1)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4445371 Ki 562.5 nM
CCC(C)N(C)C(=O)c1cc2ccccc2c(-c2ccccc2I)n1 CHEMBL1672418 IC50 620.0 nM
COc1cccc(NC[C@@H](F)Cn2c3ccc(Br)cc3c3cc(Br)ccc32)n1 CHEMBL3265237 IC50 680.0 nM
CCN(Cc1ccc(F)cc1)C(=O)Cn1c2ccccc2c2ccccc21 CHEMBL4551915 Ki 693.8 nM
O=C(O)c1cc(-c2ccc(-c3cc(CO)on3)cc2)cc(-n2cc(-c3ccc(C(F)(F)F)cc3)nn2)c1 CHEMBL4853466 Ki 751.0 nM
C#CCN(C)C(=O)c1cc2cc(NS(C)(=O)=O)ccc2n1Cc1ccc(OC)cc1 CHEMBL4743658 Ki 760.9 nM
Cc1nc(C(=O)N2CCC[C@H]2Cc2nnc(-c3ccccc3)o2)c(-c2ccccc2F)s1 CHEMBL2110363 Ki 789.49 nM
Cc1csc2c(N[C@@H](C)CN3CCN(S(=O)(=O)c4ccc(Cl)c(Cl)c4)CC3)ncnc12 CHEMBL256470 Ki 799.1 nM
CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 CHEMBL3987016 IC50 800.0 nM
COc1ccnc(N2CCC3(CCCN(Cc4c[nH]c5ccccc45)C3=O)CC2)n1 CHEMBL2435402 Ki 802.97 nM
CC(=O)N(Cc1ccc(OC(C)C)cc1)c1cc(C)cc(C)c1 CHEMBL4750722 Ki 823.0 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1cccc([N+](=O)[O-])c1 CHEMBL405355 Ki 952.9 nM
COC1CCN(c2cccc(-c3cc(NC(C)=O)nc(-n4nc(C)cc4C)n3)n2)CC1 CHEMBL487553 Ki 968.95 nM
CN(C)S(=O)(=O)c1ccc(NC(=S)N2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL2030155 Ki 969.17 nM
CC(=O)N1CCc2ccc(N(C(=O)/C=C/c3cccc(C#N)c3)C3CCN(CCC4CCCC4)CC3)cc21 CHEMBL21283 Ki 974.88 nM
C#CCN(C)C(=O)c1cc2cc(C)ccc2n1Cc1ccc(OC)nc1 CHEMBL4798757 Ki 982.7 nM
C=Cc1c(C)c2cc3nc(c4c5[nH]c(cc6nc(cc1[nH]2)C(C)=C6CC)c(C)c5C(=O)C4)[C@@H](CCC(=O)N(C)CCN(C)C(=O)c1cc2ccccc2c(-c2ccccc2I)n1)[C@@H]3C CHEMBL1672414 IC50 1000.0 nM