CC[C@@](C)(O)C#Cc1cc2c(ccn2-c2cc(OC)nc(N)n2)cn1 CHEMBL5182036 IC50 1.6 nM
CC(C)(O)C#Cc1cc2c(cn1)c(C1CC1)cn2-c1ccnc(N)n1 CHEMBL5268795 IC50 2.3 nM
CC[C@](C)(O)C#Cc1cc2c(ccn2-c2ccnc(N)n2)cn1 CHEMBL5283456 IC50 2.3 nM
CC[C@](C)(O)C#Cc1cc2c(ccn2-c2cc(OC)nc(N)n2)cn1 CHEMBL5280210 IC50 2.7 nM
CC(C)(O)C#Cc1cc2c(cn1)CCN2c1ccnc(N)n1 CHEMBL5272364 IC50 2.8 nM
CC(C)(O)C#Cc1cc2c(cn1)c(C1CCOCC1)cn2-c1ccnc(N)n1 CHEMBL5279863 IC50 7.8 nM
CC(C)(O)C#Cc1cc2c(ccn2-c2ccnc(N)n2)cn1 CHEMBL5282072 IC50 9.8 nM
CC[C@](C)(O)C#Cc1cc2c(ccn2-c2nc(N)ncc2OC)cn1 CHEMBL5268080 IC50 10.0 nM
CN1CCC[C@@H](c2cn(-c3ccnc(N)n3)c3cc(C#CC(C)(C)O)ncc23)C1 CHEMBL5271137 IC50 18.0 nM
CC[C@](C)(O)C#Cc1cc2c(cn1)cnn2-c1ccnc(N)n1 CHEMBL5273263 IC50 18.0 nM
CC[C@](C)(O)C#Cc1cc2c(ccn2-c2cc(C)nc(N)n2)cn1 CHEMBL5282902 IC50 20.0 nM
CC(C)(O)C#Cc1cc2c(ccn2-c2ccnc(N)n2)c(N2CCOCC2)n1 CHEMBL5290581 IC50 32.0 nM
CC[C@](C)(O)C#Cc1cc2c(ccn2-c2cc(N)ncn2)cn1 CHEMBL5274162 IC50 37.0 nM
COc1cc2ccn(-c3ccnc(N)n3)c2cc1C#CC(C)(C)O CHEMBL5280803 IC50 39.0 nM
COc1nc(C#CC(C)(C)O)cc2c1ccn2-c1ccnc(N)n1 CHEMBL5288487 IC50 57.0 nM
CC(C)(O)C#Cc1cc2c(cn1)cnn2-c1ccnc(N)n1 CHEMBL5278744 IC50 60.0 nM
CC(C)(O)C#Cc1cc2c(ccn2-c2ccnc(N)n2)cc1F CHEMBL5274528 IC50 86.0 nM
CC1(N)CCC(Nc2ccn3ncnc(Nc4cc(O)cc(Br)c4)c23)CC1 CHEMBL4528881 IC50 120.0 nM
CC1(N)CCN(Cc2ccn3ncnc(Nc4cc(O)cc(Br)c4)c23)CC1 CHEMBL5193906 IC50 120.0 nM
Cn1nc(-c2ccnc(N)n2)c2cc(C#CC(C)(C)O)ccc21 CHEMBL5290252 IC50 124.0 nM
CC(C)(O)C#Cc1ccc2[nH]nc(-c3ccnc(N)n3)c2c1 CHEMBL5279159 IC50 185.0 nM
CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 CHEMBL2334586 IC50 199.0 nM
COc1cc2ncnc(Nc3cccc(O)c3)c2cc1OC CHEMBL127907 Kd 240.0 nM
Clc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5204869 IC50 240.0 nM
Clc1ccccc1Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 CHEMBL5200069 IC50 330.0 nM
COc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5193488 IC50 340.0 nM
Cn1nc(-c2ccnc(N)n2)c2cc(C#CC(C)(C)O)ncc21 CHEMBL5275588 IC50 352.0 nM
Clc1ccccc1Cn1cc(COc2ccc(Nc3ncnc4[nH]ccc34)cc2)nn1 CHEMBL5181249 IC50 360.0 nM
Nc1nc(Nc2ccc(Oc3cccc(Cl)c3)cc2)c2cc[nH]c2n1 CHEMBL5184336 IC50 370.0 nM
Nc1nc(Nc2ccc(Oc3ccc(C(F)(F)F)cc3)cc2)c2cc[nH]c2n1 CHEMBL5180098 IC50 380.0 nM
c1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5198544 IC50 390.0 nM
c1ccc(CCn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)cc1 CHEMBL5178965 IC50 390.0 nM
CC(C)(O)/C=C/c1cc2c(ccn2-c2ccnc(N)n2)cn1 CHEMBL5272862 IC50 414.0 nM
O=[N+]([O-])c1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5209196 IC50 420.0 nM
N#Cc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5187459 IC50 440.0 nM
Nc1nc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)c2cc[nH]c2n1 CHEMBL5187125 IC50 450.0 nM
Clc1cccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)c1 CHEMBL5197012 IC50 480.0 nM
COc1ccc(Nc2ncnc3[nH]ccc23)cc1 CHEMBL5185704 IC50 520.0 nM
Nc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5171328 IC50 520.0 nM
Clc1ccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)cc1 CHEMBL5193034 IC50 610.0 nM
Nc1ccc(Sc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5188513 IC50 650.0 nM
Brc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5197789 IC50 750.0 nM
c1ccc(COc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5200160 IC50 750.0 nM
c1cncc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)c1 CHEMBL5206548 IC50 750.0 nM
Fc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 CHEMBL5208565 IC50 770.0 nM
c1ccc(Nc2ncnc3[nH]ccc23)cc1 CHEMBL5207783 IC50 790.0 nM
COc1cccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)c1 CHEMBL5196033 IC50 840.0 nM
Cc1ccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)cc1 CHEMBL5178462 IC50 990.0 nM
FC(F)(F)Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 CHEMBL1257781 IC50 1000.0 nM