COc1cc(C(=O)O)ccc1Oc1ccc(Cl)cc1Cl CHEMBL438498 Kd 0.2 nM
OCc1ccc(Oc2ccc(Cl)cc2Cl)c(O)c1 CHEMBL240806 Kd 0.3 nM
O=C(O)c1ccc2nc(-c3cc(Cl)cc(Cl)c3)oc2c1 CHEMBL2103837 EC50 2.7 nM
Cc1c(C(=O)O)coc1/C=C/c1ccc(Cl)o1 CHEMBL3959466 Kd 3.5 nM
Cc1oc(/C=C/c2ccc(Cl)o2)cc1C(=O)O CHEMBL3890392 Kd 3.9 nM
Cc1n[nH]c(C)c1CCCOc1cc(C(=O)O)ccc1F CHEMBL3940890 Kd 4.8 nM
Oc1cc(CCl)ccc1Oc1ccc(Cl)cc1Cl CHEMBL240805 Kd 5.7 nM
O=C1CC(c2cc(Cl)cc(Cl)c2)Oc2cc(O)cc(O)c21 CHEMBL5276223 Kd 6.0 nM
O=C(c1cc(O)cc(F)c1)c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL5203058 Kd 6.2 nM
O=C(O)c1ccc(-c2cc(F)cc(F)c2)cc1 CHEMBL432234 Kd1 9.0 nM
O=C1CC(c2cc(Cl)c(O)c(Cl)c2)Oc2cccc(O)c21 CHEMBL5268339 Kd 13.0 nM
O=Cc1ccc(Oc2ccc(Cl)cc2Cl)c(O)c1 CHEMBL240804 Kd 13.9 nM
COc1cc(C(=O)c2cc(O)cc(F)c2)cc([N+](=O)[O-])c1O CHEMBL5408344 Kd 14.0 nM
O=C1CC(c2cc(Cl)c(O)c(Cl)c2)Oc2cc(O)cc(O)c21 CHEMBL5283388 Kd 16.0 nM
Cc1ccc(C(=O)c2cc(O)c(O)c([N+](=O)[O-])c2)cc1 CHEMBL1324 Kd 20.6 nM
O=C(c1cc(F)cc(F)c1)c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL5172990 Kd 26.0 nM
O=C1CC(c2cc(Cl)c(O)c(Cl)c2)Oc2cc(O)ccc21 CHEMBL5280970 Kd 26.0 nM
O=C(O)c1ccc(Oc2ccccc2)c(O)c1 CHEMBL241454 Kd 27.0 nM
O=C(O)c1ccc(Oc2ccc(Cl)cc2Cl)c(O)c1 CHEMBL240808 Kd 27.0 nM
O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1 CHEMBL23588 Kd 30.0 nM
O=C(c1ccc(F)cc1)c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL5172066 Kd 31.0 nM
Oc1ccccc1-c1nnc(S)o1 CHEMBL240165 Kd 42.0 nM
O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl CHEMBL139 Kd1 60.0 nM
Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O CHEMBL290106 Kd 62.0 nM
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL151 Kd 70.0 nM
Cc1n[nH]c(C)c1CCCOc1cc(OCCCCCCNCCOCCOCCN=[N+]=[N-])cc(C(=O)O)c1 CHEMBL5205181 Kd 74.3 nM
O=C(O)c1cc(-c2ccc(F)cc2F)ccc1O CHEMBL898 Kd1 75.0 nM
O=C(c1cc(Cl)cc(Cl)c1)c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL5205412 Kd 85.0 nM
COc1cc(C=O)ccc1Oc1ccccc1 CHEMBL241453 Kd 88.0 nM
Cc1n[nH]c(C)c1CCCOc1cc(C(=O)O)ccc1I CHEMBL4206443 Kd 90.0 nM
Cc1ccc(C)c(OCCCC(C)(C)C(=O)O)c1 CHEMBL457 Kd 100.0 nM
O=C(Nc1nnc[nH]1)c1c(Cl)ccc(Cl)c1Cl CHEMBL394034 Kd 120.0 nM
Cc1c(Cl)cccc1Nc1ccccc1C(=O)O CHEMBL121626 Kd 150.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(C(=O)O)ccc2I)CC1 CHEMBL5089170 IC50 190.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(C(=O)O)ccc2Cl)CC1 CHEMBL5091368 IC50 200.0 nM
CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 CHEMBL388590 Kd(app) 200.0 nM
Cc1ccc(C(=O)O)cc1N1CCN(c2c(C)n[nH]c2C)CC1 CHEMBL5090952 IC50 210.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(C(=O)O)ccc2F)CC1 CHEMBL5080175 IC50 220.0 nM
O=c1cc(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL28 Kd 250.0 nM
Cc1nn(C)c(C)c1CCCOc1cc(C(=O)O)ccc1F CHEMBL4210824 Kd 251.0 nM
COC(=O)c1ccc(F)c(OCCCc2c(C)n[nH]c2C)c1 CHEMBL4218173 Kd 258.0 nM
O=C(O)c1cccnc1Nc1cccc(C(F)(F)F)c1 CHEMBL63323 Kd 260.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(C(=O)O)ccc2C(F)(F)F)CC1 CHEMBL5080942 IC50 260.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(-c3nn[nH]n3)ccc2F)CC1 CHEMBL5093498 IC50 260.0 nM
COc1ccc(/C=N/n2c(S)nnc2C(F)(F)F)cc1O CHEMBL3695459 IC50 277.0 nM
Cc1n[nH]c(C)c1CCCOc1ccccc1F CHEMBL3695460 IC50 296.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(C(=O)O)ccc2C(=O)O)CC1 CHEMBL5082796 IC50 300.0 nM
COc1c(Br)cc(/C=C2\SC(=O)NC2=O)cc1Br CHEMBL591504 IC50 301.0 nM
O=C(c1ccc(C(F)(F)F)cc1)c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL5183147 Kd 310.0 nM
O=C(O)c1cc(-c2ccc(F)cc2F)cc(I)c1O CHEMBL1232738 Kd 320.0 nM
CCOc1ccccc1-c1nc(-c2ccncc2)no1 CHEMBL1581319 IC50 329.1 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL297453 Kd 400.0 nM
O=C1CC(c2ccc(O)c(Cl)c2)Oc2cc(O)cc(O)c21 CHEMBL5290760 Kd 403.0 nM
CCc1oc2ccccc2c1C(=O)c1cc(I)c(O)c(I)c1 CHEMBL232201 Kd(app) 410.0 nM
CCc1oc2cc(O)ccc2c1C(=O)c1cc(I)c(O)c(I)c1 CHEMBL5422596 Kd(app) 410.0 nM
CC1(C)NC(=O)C(C#N)=C(SCc2ccccc2)S1 CHEMBL1835582 IC50 433.0 nM
OB(O)c1ccc(/C=C/c2cc(O)cc(O)c2)c(Cl)c1 CHEMBL4072121 Kd 440.0 nM
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)CCCCCN2C(=O)CC(SCCC(=O)NC(Cc3cn(CCOCCOCCNCCCCCCOc4cc(OCCCc5c(C)n[nH]c5C)cc(C(=O)O)c4)nn3)C(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)C2=O)C(C)C)cc1)C(C)C CHEMBL5180672 Kd 447.8 nM
O=C(O)c1cccc(/C=C/c2ccc(B(O)O)cc2Cl)c1 CHEMBL4090439 Kd 450.0 nM
Cc1n[nH]c(C)c1/C=C/c1cc(Br)c(OC(=O)c2ccc(F)cc2)c(Br)c1 CHEMBL5431059 IC50 450.0 nM
OB(O)c1ccc(/C=C/c2ccc(B(O)O)cc2Cl)c(Cl)c1 CHEMBL4078202 Kd 470.0 nM
O=C(O)c1cccc(/C=C/c2ccc(O)cc2Cl)c1 CHEMBL4069407 Kd 470.0 nM
Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1 CHEMBL165 Kd 470.0 nM
OB(O)c1ccc(/C=C/c2cc(O)cc(O)c2)cc1 CHEMBL4063503 Kd 470.0 nM
Cc1n[nH]c(C)c1/C=C/c1cc(Br)c(OC(=O)c2c(F)cc(F)cc2F)c(Br)c1 CHEMBL5419683 IC50 470.0 nM
Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl CHEMBL509 Kd 480.0 nM
Cc1ccc(O)c(Nc2ccccc2C(=O)O)c1Cl CHEMBL3695461 IC50 504.0 nM
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN2C(=O)CC(SCCC(=O)NC(Cc3cn(CCOCCOCCNCCCCCCOc4cc(OCCCc5c(C)n[nH]c5C)cc(C(=O)O)c4)nn3)C(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)C2=O)C(C)C)cc1)C(C)C CHEMBL5174982 Kd 506.6 nM
Cc1n[nH]c(C)c1CCCOc1cc(OCCCc2cn(CCOCCOCCOCCOCCNC(=O)C3CCC(CN4C(=O)C=CC4=O)CC3)nn2)cc(C(=O)O)c1 CHEMBL5081901 Kd 516.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cccc(C(=O)O)c2F)CC1 CHEMBL5091475 IC50 550.0 nM
Cc1n[nH]c(C)c1/C=C/c1cc(Br)c(OC(=O)c2c(F)cccc2F)c(Br)c1 CHEMBL5435440 IC50 570.0 nM
N#CC1(C#N)c2c([nH]c3ccccc23)OC2c3ccccc3C(=O)C21 CHEMBL3695462 IC50 586.0 nM
Cc1cc(F)c(N2CCN(c3c(C)n[nH]c3C)CC2)cc1C(=O)O CHEMBL5085751 IC50 600.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(F)cc(C(=O)O)c2)CC1 CHEMBL5089791 IC50 620.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cc(C(N)=O)ccc2F)CC1 CHEMBL5082364 IC50 670.0 nM
CCc1oc2cc(O)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 CHEMBL1767079 Kd(app) 700.0 nM
Oc1cc(O)cc(/C=C/c2ccc(O)cc2Cl)c1 CHEMBL4099088 Kd 730.0 nM
COc1cc(/C=C/c2cc(O)cc(O)c2)ccc1O CHEMBL110370 Kd(app) 730.0 nM
O=[N+]([O-])c1cc(O)c(O)c([N+](=O)[O-])c1 CHEMBL168276 IC50 741.0 nM
O=C(c1cc(O)c(O)c([N+](=O)[O-])c1)c1ccccc1F CHEMBL1256291 IC50 755.0 nM
Cc1n[nH]c(C)c1N1CCN(c2cccc(C(=O)O)c2)CC1 CHEMBL5078773 IC50 780.0 nM
OB(O)c1cccc(/C=C/c2ccc(B(O)O)cc2Cl)c1 CHEMBL4065175 Kd 790.0 nM
O=C1NC(=O)/C(=C/c2cccc(C(F)(F)F)c2)S1 CHEMBL183906 IC50 815.0 nM
Oc1ccc(/C=C/c2ccc(O)cc2Cl)c(Cl)c1 CHEMBL4102478 Kd 820.0 nM
O=C1NC(=O)/C(=C/c2cccc3ccccc23)S1 CHEMBL1348329 IC50 842.0 nM
O=C(O)c1cccc(/C=C/c2ccc(B(O)O)cc2)c1 CHEMBL4082603 Kd 990.0 nM