CNc1nc(O)c2c(n1)CCc1ccccc1-2 CHEMBL305610 I50 0.0 nM
C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL290277 Ki app 0.041 nM
C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL406575 Ki app 0.042 nM
C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL295708 Ki app 0.072 nM
Cc1nc2ccc3ccc(CNc4ccc5c(c4)CN([C@@H](CCC(=O)O)C(=O)O)C5=O)cc3c2c(=O)[nH]1 CHEMBL169896 Ki 0.09 nM
Cc1nc(O)c2c(ccc3ccc(CNc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c4)cc32)n1 CHEMBL355323 Ki 0.09 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccc(C(=O)N[C@H](CCC(=O)O)C(=O)O)cc1 CHEMBL166027 Ki 0.124 nM
C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL295681 Ki app 0.224 nM
Cc1nc(O)c2c(ccc3ccc(CNc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)cc32)n1 CHEMBL168907 Ki 0.44 nM
Cc1nc(O)c2c(ccc3ccc(CNc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s4)cc32)n1 CHEMBL169506 Ki 1.1 nM
Nc1nc(O)c2c(ccc3ccc(CNc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)cc32)n1 CHEMBL355662 Ki 1.2 nM
C#CCN(c1ccc(C(=O)N[C@@H](CCC(=O)N[C@H](CCC(=O)O)C(=O)O)C(=O)O)cc1)C1CCc2cc3nc(CO)[nH]c(=O)c3cc21 CHEMBL1253498 IC50 1.2 nM
Nc1nc2[nH]cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)c2c(=O)[nH]1 CHEMBL225072 Ki 1.3 nM
Cc1nc(O)c2c(Sc3ccc(C(=O)N[C@H](CCC(=O)O)C(=O)O)cc3)c(C)ccc2n1 CHEMBL166369 Ki 1.31 nM
CN(C)c1cccc2c(S(=O)(=O)Oc3ccc(C[C@H](NS(=O)(=O)c4cc5nnoc5c5ccccc45)C(=O)O)cc3)cccc12 CHEMBL179448 Ki 1.5 nM
CNC1=Nc2ccc(N(C)Cc3ccc(S(=O)(=O)N4CCOCC4)cc3)c3c(C)ccc1c23 CHEMBL9671 Ki 2.0 nM
CN(Cc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL9440 Ki 2.0 nM
C#CN(Cc1cc2c(=O)[nH]c(C)nc2cc1C)c1ccc(C(=O)N[C@@H](CCc2nnnn2CC(=O)O)C(=O)O)c(F)c1 CHEMBL4531593 IC50 2.4 nM
Cc1nc(O)c2c(ccc3ccc(CN(C)c4ccc5c(c4)CN([C@@H](CCC(=O)O)C(=O)O)C5=O)cc32)n1 CHEMBL355616 Ki 2.5 nM
Nc1nc(O)c2c(n1)CCc1ccc(S(=O)(=O)Nc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc1-2 CHEMBL325972 Ki 2.5 nM
Nc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1)CCC3 CHEMBL169921 Kii 2.6 nM
COC(=O)[C@@H](NC(=O)c1ccc(Sc2c(C)ccc3nc(N)nc(O)c23)cc1)c1ccccc1 CHEMBL321678 IC50 3.0 nM
COC(=O)[C@H](NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)cc1)c1ccccc1 CHEMBL5267424 IC50 3.0 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccc(C(=O)N[C@H](C(=O)O)c2ccccc2)cc1 CHEMBL111859 IC50 3.0 nM
COC(=O)[C@@H](NC(=O)c1ccc(Sc2c(C)ccc3nc(N)nc(O)c23)cc1)c1cccc(O)c1 CHEMBL113019 IC50 3.0 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccc(C(=O)N[C@H](C(=O)O)c2cccc(O)c2)cc1 CHEMBL109881 IC50 3.0 nM
COC(=O)c1cccc([C@H](NC(=O)c2ccc(Sc3c(C)ccc4nc(N)nc(O)c34)cc2)C(=O)OC)c1 CHEMBL320036 IC50 3.0 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccc(C(=O)N[C@H](C(=O)O)c2cccc(C(=O)O)c2)cc1 CHEMBL264198 IC50 3.0 nM
Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@H](C)c2ccccc2)cc1 CHEMBL5289121 IC50 3.0 nM
Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@H](CO)c2ccccc2)cc1 CHEMBL5289689 IC50 3.0 nM
COC(=O)[C@@H](NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)s1)c1ccccc1 CHEMBL5283610 IC50 3.0 nM
COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)cc1 CHEMBL5287291 IC50 3.0 nM
Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)O)cc1 CHEMBL5288172 IC50 3.0 nM
COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)cc1 CHEMBL5268759 IC50 3.0 nM
COC(=O)[C@H](Cc1ccc(O)c(O)c1)NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)cc1 CHEMBL5286548 IC50 3.0 nM
COC(=O)[C@H](Cc1ccc(N)cc1)NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)cc1 CHEMBL5282201 IC50 3.0 nM
COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccc(Sc2c(C)ccc3nc(N)[nH]c(=O)c23)cc1 CHEMBL5266971 IC50 3.0 nM
COC(=O)c1cccc(NC(=O)c2ccc(Sc3c(C)ccc4nc(N)[nH]c(=O)c34)cc2)c1 CHEMBL5271165 IC50 3.0 nM
Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)Nc2cccc(C(=O)O)c2)cc1 CHEMBL5273148 IC50 3.0 nM
Nc1nc2[nH]c3cccc(Sc4ccc5ccccc5c4)c3c2c(=O)[nH]1 CHEMBL3099582 Ki 3.3 nM
Cc1nc(O)c2c(ccc3ccc(CNc4ccc5c(=O)n([C@@H](CCC(=O)O)C(=O)O)sc5c4)cc32)n1 CHEMBL167164 Ki 4.0 nM
Cc1cc(CN(C)c2ccc3c4c(ccc(C)c24)C(N)=N3)ccn1 CHEMBL55263 Ki 4.0 nM
CN(C)c1cccc2c(S(=O)(=O)Oc3ccc(C[C@H](NS(=O)(=O)c4cccc5cc([N+](=O)[O-])ccc45)C(=O)O)cc3)cccc12 CHEMBL362606 Ki 4.1 nM
C#CCN(Cc1ccc2[nH]c(N)nc(=O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL422395 Ki 4.5 nM
C#CN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL1160192 IC50 4.7 nM
O=c1[nH]c(=O)n([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]2F)cc1F CHEMBL253954 Ki 4.77 nM
Cc1nc(O)c2c(ccc3ccc(S(=O)(=O)Nc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)cc32)n1 CHEMBL324739 Ki 5.5 nM
C#CN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL1160188 IC50 5.5 nM
Cc1ccc2c3c(ccc(N(C)Cc4ccncc4)c13)N=C2N CHEMBL56523 Ki 6.0 nM
Nc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)N2CCOCC2)cc1)CCC3 CHEMBL168524 Ki 6.0 nM
Nc1nc2cc3c(cc2[nH]1)N(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CCC3 CHEMBL169411 Kii 6.0 nM
C#CN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)cc1 CHEMBL1160181 IC50 6.3 nM
C#CCN(Cc1ccc2[nH]c(N)nc(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL389051 Ki 7.0 nM
N#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL34918 Ki app 7.01 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL25889 Ki 8.5 nM
CN(C)c1cccc2c(S(=O)(=O)Oc3ccc(C[C@H](NS(=O)(=O)c4cccc5cc(N)ccc45)C(=O)O)cc3)cccc12 CHEMBL360335 Ki 8.5 nM
C#CCN(Cc1ccc2nc(N)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL104230 pIC50 8.913 nM
Cc1nc(=O)c2cc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)ccc2[nH]1 CHEMBL225071 IC50 9.0 nM
Cc1ccc2c3c(ccc(N(C)Cc4ccnnc4)c13)N=C2N CHEMBL57420 Ki 10.0 nM
C#CN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL1160189 IC50 10.0 nM
C#CN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC=O)C(=O)O)cc1 CHEMBL1160200 IC50 10.0 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccnnc1 CHEMBL349723 Ki 11.0 nM
CN(C)c1cccc2c(S(=O)(=O)Oc3ccc(C[C@H](NS(=O)(=O)c4ccc(NC(=O)OCc5ccccc5)c5ccccc45)C(=O)O)cc3)cccc12 CHEMBL425692 Ki 11.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2)cc1 CHEMBL417222 Ki 12.0 nM
CN(C)c1cccc2c(S(=O)(=O)Oc3ccc(C[C@H](NS(=O)(=O)c4cccc5c(NC(=O)OCc6ccccc6)cccc45)C(=O)O)cc3)cccc12 CHEMBL360758 Ki 13.0 nM
Nc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)CCC3 CHEMBL301256 Ki 13.1 nM
CNC1=Nc2ccc(N(C)Cc3ccncc3)c3c(C)ccc1c23 CHEMBL59203 Ki 14.0 nM
Cc1cc(CN(C)c2ccc3c4c(cccc24)C(N)=N3)ccn1 CHEMBL434980 Ki 14.0 nM
O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)cc1F CHEMBL886 Ki 14.0 nM
CN(Cc1ccnnc1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL293823 Ki 15.0 nM
Cc1ccc2nc(N)[nH]c(=O)c2c1Sc1ccncc1 CHEMBL320775 Ki 15.0 nM
CN(Cc1ccncc1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL55884 Ki 17.0 nM
CN(Cc1ccnc(CO)c1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL294871 Ki 18.0 nM
Cc1nc(O)c2c(n1)CCc1ccc(S(=O)(=O)Nc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc1-2 CHEMBL324932 Ki 18.0 nM
Nc1nc(O)c2c(Sc3ccncc3)c(Cl)ccc2n1 CHEMBL162145 Ki 18.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL169981 pIC50 19.95 nM
Cc1cc2nc(N)nc(O)c2c2cc(Cl)ccc12 CHEMBL310936 I50 20.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2)c(F)c1 CHEMBL158542 Ki 20.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2Cl)cc1 CHEMBL159213 Ki 21.0 nM
Cc1nc(O)c2c(ccc3ccc(CN(C)c4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)cc32)n1 CHEMBL168367 Ki 22.0 nM
Nc1nc(O)c2c(ccc3ccc(I)cc32)n1 CHEMBL306597 I50 22.0 nM
Nc1nc(O)c2c(ccc3ccc(Br)cc32)n1 CHEMBL306705 I50 22.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2)c(Cl)c1 CHEMBL162076 Ki 24.0 nM
COc1ccc(S(=O)(=O)c2ccc(CN3CCCc4cc5[nH]c(N)nc5cc43)cc2)cc1 CHEMBL171314 Ki 24.0 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccnc(C(F)(F)F)c1 CHEMBL351885 Ki 24.0 nM
Nc1nc(O)c2c(ccc3ccc(Cl)cc32)n1 CHEMBL306775 I50 25.0 nM
CCc1cc(CN(C)c2ccc3c4c(cccc24)C(N)=N3)ccn1 CHEMBL56611 Ki 25.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2C)cc1 CHEMBL159364 Ki 26.0 nM
C#CCN(Cc1ccc2ncnc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL171480 Ki 26.0 nM
Nc1nc(O)c2c(n1)CCC(CNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)N2Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O CHEMBL2368783 Ki 27.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)c(Cl)c1 CHEMBL160215 Ki 27.0 nM
CNC1=Nc2ccc(N(C)Cc3ccnnc3)c3c(C)ccc1c23 CHEMBL293810 Ki 30.0 nM
NC1=NC(=O)C2C(=N1)CCC(CNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)N2Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O CHEMBL3392216 Ki 30.0 nM
CN(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL275685 Ki 31.0 nM
Cc1ccc2nc(N)nc(O)c2c1Sc1ccnc(N(C)C)c1 CHEMBL351606 Ki 32.0 nM
Nc1nc2sc3cccc(CNc4ccc5c(c4)CN([C@@H](CCC(=O)O)C(=O)O)C5=O)c3c2c(=O)[nH]1 CHEMBL1738740 IC50 34.0 nM
C#CCN(Cc1ccc2nc(OC)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL105026 pIC50 36.31 nM
Cc1nc(N)nc(O)c1N(CCN(C)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O CHEMBL2368784 Ki 37.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2)c(C(F)(F)F)c1 CHEMBL291548 Ki 37.0 nM
COc1cc(Sc2c(C)ccc3nc(C)nc(O)c23)ccn1 CHEMBL163411 Ki 37.0 nM
Nc1nc2cc3c(cc2[nH]1)N(Cc1ccc2cc(CO)ccc2c1)CCC3 CHEMBL353813 Ki 38.0 nM
Cc1cc(Sc2c(C)ccc3nc(C)nc(O)c23)ccn1 CHEMBL350130 Ki 39.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL434209 pIC50 39.81 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)nc1 CHEMBL291075 pIC50 39.81 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N(CCC(=O)O)C(=O)O)cc1 CHEMBL522363 IC50 40.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL306149 IC50 42.0 nM
CC1=C(Sc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)C2C(=O)NC(N)=NC2N1 CHEMBL336487 IC50 42.0 nM
Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL225180 IC50 42.0 nM
Cc1nc2ccc(CN(CCF)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 CHEMBL104358 pIC50 42.66 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL104856 pIC50 44.67 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2C)cc1 CHEMBL159209 Ki 45.0 nM
CN(Cc1ccnc(C(F)(F)F)c1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL301218 Ki 45.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2Cl)cc1 CHEMBL161685 Ki 46.0 nM
Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL252132 IC50 46.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)c(F)c1 CHEMBL161025 Ki 50.0 nM
COc1ccc(S(=O)(=O)c2ccc(CN3CCCc4cc5c(cc43)nc(N)n5C)cc2)cc1 CHEMBL171057 Ki 51.0 nM
Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(Cl)c1 CHEMBL224868 IC50 51.0 nM
CN(Cc1ccnc(Sc2ccccc2)c1)c1ccc2c3c(cccc13)C(N)=N2 CHEMBL56637 Ki 52.0 nM
Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL388340 IC50 54.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL551049 IC50 54.0 nM
Nc1nc2[nH]c3cccc(Sc4ccccc4)c3c2c(=O)[nH]1 CHEMBL3099580 Ki 55.7 nM
Cc1nc(O)c2c(Sc3ccc([N+](=O)[O-])cc3)c(C)ccc2n1 CHEMBL162613 Ki 56.0 nM
Nc1nc(O)c2c(n1)CCc1cc(S(=O)(=O)Nc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)ccc1-2 CHEMBL116589 Ki 57.0 nM
CCOC(=O)C1CCC(c2ccccc2)N1C(=O)c1cn(CCCNC(=O)C(F)(F)F)nn1 CHEMBL4857252 IC50 57.0 nM
C#CCN(Cc1ccc2nc[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL420280 pIC50 57.54 nM
C#CCN(Cc1ccc2nc(CO)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL104410 pIC50 57.54 nM
Cc1nc(O)c2c(Sc3ccncc3)c(C)ccc2n1 CHEMBL351403 Ki 58.0 nM
Cc1nc(O)c2c(Sc3ccnc(N(C)C)c3)c(C)ccc2n1 CHEMBL349969 Ki 58.0 nM
Nc1nc2c(c(=O)[nH]1)N(Cc1cn([C@H]3C[C@H](O)[C@@H](COP(O)O)O3)c(=O)[nH]c1=O)C(CNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CC2 CHEMBL3144212 Ki 58.0 nM
CN1CCN(Cc2cn([C@H]3C[C@H](O)[C@@H](COP(=O)(O)O)O3)c(=O)[nH]c2=O)c2ccccc21 CHEMBL3392217 Ki 60.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)cc1 CHEMBL162754 Ki 61.0 nM
Nc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)N2CCNCC2)cc1)CCC3 CHEMBL56662 Ki 64.0 nM
Cc1nc(O)c2c(Sc3ccc(C(=O)O)cc3)c(C)ccc2n1 CHEMBL165453 Ki 65.0 nM
C#CCN(Cc1ccc2nc(OC)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL265098 pIC50 67.61 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(OC)c1 CHEMBL323363 pIC50 67.61 nM
CCCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL1160054 IC50 68.0 nM
Nc1nc2sc3cccc(CNc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)c3c2c(=O)[nH]1 CHEMBL1738741 IC50 68.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)n2ccc3ccccc32)cc1 CHEMBL299928 Ki 69.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)c(C(F)(F)F)c1 CHEMBL161450 Ki 70.0 nM
Cc1nc(O)c2c(Sc3ccnc(C(F)(F)F)c3)c(C)ccc2n1 CHEMBL163410 Ki 70.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(Cl)c1 CHEMBL323375 pIC50 74.13 nM
C=CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c1 CHEMBL320108 pIC50 75.86 nM
Cc1nc(O)c2c(Sc3ccc(S(=O)(=O)c4ccccc4)cc3)c(C)ccc2n1 CHEMBL423282 Ki 76.0 nM
Cc1nc2ccc(CN(CCO)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 CHEMBL105425 pIC50 77.62 nM
Nc1nc(O)c2c(n1)CCc1cc(Br)c(S(=O)(=O)Nc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc1-2 CHEMBL117611 Ki 79.0 nM
Cc1nc(O)c2c(Sc3ccnnc3)c(C)ccc2n1 CHEMBL164624 Ki 87.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(O)c1 CHEMBL320621 pIC50 89.13 nM
C#CCN(Cc1cnc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL114987 IC50 90.0 nM
CCc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL371860 IC50 90.0 nM
C#CCN(Cc1ccc2nc(CO)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL321977 pIC50 97.72 nM
Nc1nc(O)c2c(n1)CCc1ccc(I)cc1-2 CHEMBL74847 I50 102.0 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc([N+](=O)[O-])cc1 CHEMBL492836 IC50 110.0 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)c(Cl)c1 CHEMBL492838 IC50 110.0 nM
C=Cc1ccc2ccc3nc(N)nc(O)c3c2c1 CHEMBL75213 I50 120.0 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc2ccccc2c1 CHEMBL495124 IC50 120.0 nM
Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3ccc4ccccc4c3)c12 CHEMBL4060383 IC50 120.0 nM
Cc1nc2ccc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 CHEMBL307914 pIC50 120.23 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(Cl)c1 CHEMBL105899 pIC50 120.23 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c([N+](=O)[O-])c1 CHEMBL320464 pIC50 128.82 nM
Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)c(Cl)c1 CHEMBL400485 IC50 130.0 nM
Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc([N+](=O)[O-])cc1 CHEMBL400364 IC50 130.0 nM
O=c1[nH]cc(S(=O)(=O)Nc2ccccc2-c2cn(-c3ccc(Cl)cc3)nn2)c(=O)[nH]1 CHEMBL4550585 IC50 130.0 nM
Nc1nc2[nH]cc(Cc3ccc(C(=O)Nc4cccc(C(=O)O)c4)cc3)c2c(=O)[nH]1 CHEMBL4470361 IC50 130.0 nM
COc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1 CHEMBL4096329 IC50 140.0 nM
C#CCN(Cc1ccc2nc(CC)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL105370 pIC50 141.25 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c([N+](=O)[O-])c1 CHEMBL101425 pIC50 144.54 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(S(=O)(=O)c2ccccc2C)c(C(F)(F)F)c1 CHEMBL159144 Ki 150.0 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)nc1 CHEMBL43454 pIC50 151.36 nM
C#CCN(Cc1cc2c(=O)[nH]c(C)nc2cc1Br)c1ccc(C(=O)NCc2ccncc2)cc1 CHEMBL1801873 IC50 156.0 nM
C#CCN(Cc1cc2c(=O)[nH]c(C)nc2cc1Br)c1ccc(C(=O)NCc2ccccn2)cc1 CHEMBL1801872 IC50 156.0 nM
C#CCN(Cc1cc2c(O)nc(C)nc2cc1Br)c1ccc(C(=O)NCc2cccnc2)cc1 CHEMBL123446 IC50 156.0 nM
Cc1nc(O)c2c(ccc3ccc(I)cc32)n1 CHEMBL75136 I50 157.0 nM
Cc1nc2ccc(CN(CCF)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)nc3)cc2c(=O)[nH]1 CHEMBL41609 pIC50 158.49 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL44037 pIC50 169.82 nM
C#CCN(Cc1ccc2nc[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL103059 pIC50 169.82 nM
Cc1nc2ccc(CN(CC#N)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 CHEMBL321527 pIC50 169.82 nM
Cc1ccc2ccc3nc(N)nc(O)c3c2c1 CHEMBL312542 I50 178.0 nM
C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)N[C@H](CCC(=O)O)C(=O)O)cc1 CHEMBL265510 IC50 180.0 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(OC)c1 CHEMBL105435 pIC50 190.55 nM
Cc1nc2ccc(CN(CCF)c3cnc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)cc2c(=O)[nH]1 CHEMBL1094274 pIC50 190.55 nM
CCc1ccc2nc(C)nc(O)c2c1Sc1ccncc1 CHEMBL351840 Ki 200.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Br)c([N+](=O)[O-])c1 CHEMBL195355 IC50 210.0 nM
O=C(O)CC[C@H](NC(=O)c1ccc(N(CCF)Cc2ccc3nc(CO)[nH]c(=O)c3c2)cc1)C(=O)O CHEMBL104846 pIC50 218.78 nM
C#CCN(Cc1ccc2nc(-c3ccccc3)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL420279 pIC50 218.78 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Br)c(Cl)c1 CHEMBL372371 IC50 220.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc([N+](=O)[O-])cc1 CHEMBL564937 IC50 220.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1cnc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s1 CHEMBL1095919 pIC50 229.09 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1cnc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s1 CHEMBL1097599 pIC50 229.09 nM
Nc1nc(O)c2c(ccc3ccc(Br)c([N+](=O)[O-])c32)n1 CHEMBL263192 I50 230.0 nM
Nc1nc2cc3c(cc2[nH]1)CCCC3Sc1ccc(S(=O)(=O)c2ccccc2)cc1 CHEMBL353191 Ki 230.0 nM
CCc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Cl)c(Cl)c1 CHEMBL201941 IC50 230.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)c(Cl)c1 CHEMBL556091 IC50 230.0 nM
Cc1nc2ccc(CN(CCF)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1 CHEMBL104759 pIC50 239.88 nM
C#CCN(Cc1ccc2nc(CSc3ncccn3)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL317901 pIC50 239.88 nM
CCc1[nH]c2nc(N)nc(O)c2c1Sc1ccc([N+](=O)[O-])cc1 CHEMBL201617 IC50 240.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2C)c(C(F)(F)F)c1 CHEMBL157702 Ki 260.0 nM
COc1ccc2nc(C)nc(O)c2c1Sc1ccncc1 CHEMBL164289 Ki 260.0 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)cc1 CHEMBL522517 IC50 260.0 nM
O=P(O)(O)CCCP(=O)(O)O CHEMBL1230579 Ki 260.0 nM
Cc1nc2sc3cccc(CNc4ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc4)c3c2c(=O)[nH]1 CHEMBL1818548 IC50 260.0 nM
Nc1nc2[nH]cc(Cc3ccc(C(=O)Nc4cc(C(=O)O)ccc4C(=O)O)cc3)c2c(=O)[nH]1 CHEMBL4562561 IC50 260.0 nM
Nc1nc2[nH]cc(Cc3ccc(C(=O)Nc4cc(C(=O)O)ccc4CC(=O)O)cc3)c2c(=O)[nH]1 CHEMBL4451239 IC50 260.0 nM
CCN(Cc1ccc2nc(CO)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL104483 pIC50 263.03 nM
Oc1nc(NCc2ccccc2)nc2ccc3ccc(Cl)cc3c12 CHEMBL76122 I50 270.0 nM
CNC1=Nc2ccc(N(C)Cc3ccncc3)c3cccc1c23 CHEMBL55361 Ki 270.0 nM
CN(Cc1nc2cc(C(F)(F)F)ccc2nc1-c1ccccc1)c1ccc(F)c(F)c1 CHEMBL3121462 Ki 270.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(C#N)cc1 CHEMBL195867 IC50 280.0 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccncc1 CHEMBL495125 IC50 280.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1ccncc1 CHEMBL550842 IC50 280.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(N)c1 CHEMBL104096 pIC50 288.4 nM
Cc1nc(O)c2c(ccc3ccc(Br)cc32)n1 CHEMBL307015 I50 290.0 nM
CN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL347223 IC50 290.0 nM
O=C1OC(=O)c2cc(NS(=O)(=O)c3cccc4cccnc34)cc3cccc1c23 CHEMBL2323396 Ki 300.0 nM
O=C1OC(=O)c2cc(NS(=O)(=O)c3ccccc3)cc3cccc1c23 CHEMBL2323388 Ki 300.0 nM
Cc1nc2ccc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1 CHEMBL40321 pIC50 302.0 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(N)c1 CHEMBL102275 pIC50 309.03 nM
CNC1=Nc2ccc(N(C)Cc3ccnnc3)c3cccc1c23 CHEMBL417763 Ki 310.0 nM
Cc1nc(O)c2c(Sc3cccnc3)c(C)ccc2n1 CHEMBL162498 Ki 310.0 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(C)c1 CHEMBL104871 pIC50 316.23 nM
O=C(O)CC[C@H](NC(=O)c1ccc(N(CCF)Cc2ccc3nc(CF)[nH]c(=O)c3c2)cc1)C(=O)O CHEMBL102469 pIC50 338.84 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccncc1 CHEMBL57310 IC50 340.0 nM
Nc1nc(O)c2c(ccc3cc(N)c(Br)cc32)n1 CHEMBL75044 I50 340.0 nM
CC1=C(Sc2ccncc2)C2C(=O)NC(N)=NC2N1 CHEMBL138500 IC50 340.0 nM
Cc1nc2[nH]c(C)c(Sc3ccncc3)c2c(=O)[nH]1 CHEMBL1096259 IC50 340.0 nM
CN1CCN(C(=O)Cn2c(-c3ccc(Cl)cc3)csc2=N)CC1 CHEMBL2437298 Ki 340.0 nM
Nc1nc(O)c2c(n1)CCc1ccc(Cl)cc1-2 CHEMBL76322 I50 343.0 nM
Cc1nc2ccc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)nc3)cc2c(=O)[nH]1 CHEMBL295866 pIC50 346.74 nM
Nc1nc(O)c2c(ccc3ccc(Br)c(N)c32)n1 CHEMBL73440 I50 360.0 nM
CC1Cc2nc(N)nc(O)c2-c2cc(Cl)ccc21 CHEMBL73487 I50 370.0 nM
CCN(Cc1ccc2nc(CF)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL103029 pIC50 371.54 nM
Nc1nc2[nH]c3cccc(Sc4cccc5ccccc45)c3c2c(=O)[nH]1 CHEMBL3099581 Ki 378.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1cccc(Cl)c1 CHEMBL551985 IC50 380.0 nM
C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1cccc(C(F)(F)F)c1 CHEMBL301423 Ki 390.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Br)cc1 CHEMBL565179 IC50 390.0 nM
Cc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1 CHEMBL1093100 IC50 390.0 nM
COCc1ccc(C(=O)O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1 CHEMBL4459197 IC50 390.0 nM
O=C1OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccc3ccccc3c21 CHEMBL386442 Ki 400.0 nM
Cc1nc2ccc(CN(C)c3cnc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)cc2c(=O)[nH]1 CHEMBL1097598 pIC50 416.87 nM
Cc1nc2ccc(CN(CCO)c3cnc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)cc2c(=O)[nH]1 CHEMBL1094275 pIC50 416.87 nM
C#CCN(Cc1ccc2c(c1)C(=O)N[C@H](C)N2)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL330484 I50 430.0 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s1 CHEMBL1095264 pIC50 436.52 nM
Cc1nc(O)c2c(ccc3ccc(Cl)cc32)n1 CHEMBL74724 I50 440.0 nM
COc1ccc(S(=O)(=O)c2ccc(CN3CCCc4cc5[nH]c(C)nc5cc43)cc2)cc1 CHEMBL169727 Ki 440.0 nM
O=c1[nH]cc(S(=O)(=O)Nc2cccc(-c3cn(-c4ccc(Cl)cc4)nn3)c2)c(=O)[nH]1 CHEMBL4546953 IC50 450.0 nM
CSc1ccc2ccc3nc(N)nc(O)c3c2c1 CHEMBL72371 I50 460.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Br)cc1 CHEMBL195782 IC50 460.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL371698 IC50 460.0 nM
N#Cc1ccc(C(=O)O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1 CHEMBL4565065 IC50 460.0 nM
Nc1nc2[nH]cc(Cc3ccc(C(=O)Nc4ccc(C(=O)O)cc4)cc3)c2c(=O)[nH]1 CHEMBL4544605 IC50 470.0 nM
C=CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL323539 pIC50 478.63 nM
C#CCN(Cc1ccc2nc(CNC(C)=O)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL105726 pIC50 478.63 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(C(F)(F)F)c1 CHEMBL102938 pIC50 478.63 nM
Nc1nc(O)c2c(ccc3ccc(O)cc32)n1 CHEMBL306790 I50 480.0 nM
COc1ccc(S(=O)(=O)c2ccc(CN3CCCc4cc5c(cc43)nc(C)n5C)cc2)cc1 CHEMBL352620 Ki 480.0 nM
CN(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)c1cnc2nc(N)nc(O)c2c1 CHEMBL156551 I50 480.0 nM
Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3ccc(Cl)cc3)c12 CHEMBL4079829 IC50 480.0 nM
CCc1ccc2ccc3nc(N)nc(O)c3c2c1 CHEMBL307237 I50 490.0 nM
Nc1nc(O)c2c(ccc3ccc(F)cc32)n1 CHEMBL74440 I50 500.0 nM
O=C1OC(=O)c2cc(NS(=O)(=O)c3cccs3)cc3cccc1c23 CHEMBL2323391 Ki 500.0 nM
Cc1nc2ccc(CN(CCO)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1 CHEMBL104025 pIC50 501.19 nM
C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(C)c1 CHEMBL323294 pIC50 501.19 nM
C#CCN(Cc1nc2cc(C(F)(F)F)ccc2nc1-c1ccccc1)c1ccc(C)cc1 CHEMBL3121447 Ki 510.0 nM
Oc1nc(NCc2ccccc2)nc2ccc3c(Br)cccc3c12 CHEMBL73314 I50 520.0 nM
Cc1nc2ccc(CN(CCCO)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1 CHEMBL104748 pIC50 537.03 nM
O=CNc1nc(O)c2c(ccc3ccc(Br)cc32)n1 CHEMBL75759 I50 540.0 nM
Cc1c(Sc2ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc2)[nH]c2nc(N)nc(N)c12 CHEMBL389643 IC50 540.0 nM
Nc1nc(N)c2c(n1)[nH]c1cccc(Sc3ccccc3)c12 CHEMBL1093099 IC50 540.0 nM
Cc1nc2ccc(CN(CCF)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)cc2c(=O)[nH]1 CHEMBL1096899 pIC50 549.54 nM
O=c1[nH]cc(S(=O)(=O)Nc2cccc(-c3cn(-c4cccc(Cl)c4)nn3)c2)c(=O)[nH]1 CHEMBL4587877 IC50 560.0 nM
C#CCN(Cc1ccc2nc(CF)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL322176 pIC50 575.44 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s1 CHEMBL1095266 pIC50 575.44 nM
Cc1nc2ccc(CN(CCCO)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 CHEMBL104851 pIC50 588.84 nM
C#Cc1ccc2ccc3nc(N)nc(O)c3c2c1 CHEMBL423859 I50 600.0 nM
CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL34259 Ki 600.0 nM
O=C1OC(=O)c2cc(NS(=O)(=O)/C=C/c3ccccc3)cc3cccc1c23 CHEMBL2323403 Ki 600.0 nM
O=c1[nH]cc(S(=O)(=O)Nc2ccccc2-c2cn(-c3cccc(Cl)c3)nn2)c(=O)[nH]1 CHEMBL4457367 IC50 600.0 nM
COc1ccc(C(=O)O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1 CHEMBL4476613 IC50 600.0 nM
C#CCN(Cc1ccc2nc(C(C)C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL102317 pIC50 616.6 nM
Cc1ncc([N+](=O)[O-])n1CCSc1nnc(-c2ccccc2[N+](=O)[O-])o1 CHEMBL2348578 IC50 620.0 nM
Nc1ccc2ccc3nc(N)nc(O)c3c2c1 CHEMBL73200 I50 630.0 nM
CN(Cc1ccc2nc(CO)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL321284 pIC50 645.65 nM
C#CCN(c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1)S(=O)(=O)c1ccc2c(c1)CCc1nc(N)nc(O)c1-2 CHEMBL333402 Ki 660.0 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1F CHEMBL105384 pIC50 676.08 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1cc(Cl)cc(Cl)c1 CHEMBL560912 IC50 690.0 nM
COc1ccc(Nc2nc3cc([N+](=O)[O-])cc([N+](=O)[O-])c3nc2-c2ccccc2)cc1 CHEMBL463668 Ki 700.0 nM
COc1ccc(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c(C(=O)O)c1 CHEMBL4458803 IC50 700.0 nM
Nc1nc(O)c2c(ccc3cc(Cl)c(Cl)cc32)n1 CHEMBL73594 I50 710.0 nM
Cc1ccc2c(c1)-c1c(O)nc(N)nc1CC2 CHEMBL306046 I50 720.0 nM
C#CCN(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)Cc1ccc2ccnc(O)c2c1 CHEMBL92234 I50 740.0 nM
O=c1[nH]cc(S(=O)(=O)Nc2ccc(-c3cn(-c4ccc(Cl)cc4)nn3)cc2)c(=O)[nH]1 CHEMBL4460523 IC50 740.0 nM
CN(CC1CNc2nc(N)[nH]c(=O)c2N1Cc1c[nH]c(=O)[nH]c1=O)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 CHEMBL1161432 Ki 750.0 nM
CCc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)cc1 CHEMBL564277 IC50 750.0 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ncc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s1 CHEMBL1097597 pIC50 758.58 nM
C=CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)nc1 CHEMBL41445 pIC50 758.58 nM
CNc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)CCC3 CHEMBL169726 Ki 770.0 nM
CN(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)c1ccc2c3c(cccc13)C(=O)N2 CHEMBL301844 Ki 770.0 nM
O=C(O)CC[C@H](NC(=O)c1ccc(N(CCO)Cc2ccc3nc(CO)[nH]c(=O)c3c2)cc1)C(=O)O CHEMBL105519 pIC50 776.25 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(C(F)(F)F)cc1 CHEMBL364453 IC50 800.0 nM
Cc1nc2sc3cccc(CNc4ccc5c(c4)CN([C@@H](CCC(=O)O)C(=O)O)C5=O)c3c2c(=O)[nH]1 CHEMBL1818549 IC50 800.0 nM
Cn1cc(-c2ccc(S(=O)(=O)Nc3cc4c5c(cccc5c3)C(=O)OC4=O)s2)cc1C(F)(F)F CHEMBL2323362 Ki 800.0 nM
O=C1OC(=O)c2cc(NS(=O)(=O)c3cccc4ccccc34)cc3cccc1c23 CHEMBL2323395 Ki 800.0 nM
COc1ccc(CC(=O)O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1 CHEMBL4445927 IC50 800.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(F)c(Cl)c1 CHEMBL370106 IC50 830.0 nM
CN(Cc1ccc(S(=O)(=O)N2CCNCC2)cc1)c1ccc2c3c(cccc13)C(=O)N2 CHEMBL57002 Ki 840.0 nM
Cc1nc2ccc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(N)c3)cc2c(=O)[nH]1 CHEMBL105597 pIC50 851.14 nM
O=c1[nH]cc(S(=O)(=O)Nc2ccccc2-c2cn(-c3ccccc3Cl)nn2)c(=O)[nH]1 CHEMBL4543727 IC50 870.0 nM
COC(=O)[C@@H](NP(=O)(O)OC[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)C[C@@H]1O)C1C=Nc2ccccc21 CHEMBL1791078 IC50 890.0 nM
COc1cc(-c2nnc(SCCn3c([N+](=O)[O-])cnc3C)o2)cc(OC)c1OC CHEMBL2348559 IC50 890.0 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(F)c(F)c1 CHEMBL371913 IC50 900.0 nM
Nc1cc(N)c2nc(-c3ccccc3)c(Nc3ccc(Cl)c(Cl)c3)nc2c1 CHEMBL465890 Ki 900.0 nM
O=C1OC(=O)c2cc(NS(=O)(=O)c3ccc(C(F)(F)F)cc3[N+](=O)[O-])cc3cccc1c23 CHEMBL2323392 Ki 900.0 nM
C=CCN(Cc1ccc2nc(CO)[nH]c(=O)c2c1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL105045 pIC50 912.01 nM
Cc1ncc([N+](=O)[O-])n1CCSc1nnc(-c2ccnc(N)c2)o1 CHEMBL2348566 IC50 920.0 nM
Cc1nc2ccc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c(C)c3)cc2c(=O)[nH]1 CHEMBL320470 pIC50 933.25 nM
CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1nnc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s1 CHEMBL1097931 pIC50 933.25 nM
Cc1nc(O)c2c(Sc3ccncc3)cccc2n1 CHEMBL163096 Ki 960.0 nM
Cc1nc2ccc(CN(CCCO)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3F)cc2c(=O)[nH]1 CHEMBL104670 pIC50 977.24 nM
Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Cl)cc1 CHEMBL142176 IC50 1000.0 nM
Nc1nc(O)c2c(n1)CCc1ccc(Br)cc1-2 CHEMBL306308 I50 1000.0 nM
O=c1nc(NO)ccn1[C@H]1C[C@H](O)[C@@H](COP(=O)(O)O)O1 CHEMBL1161227 Kd 1000.0 nM
Cc1nc(N)nc2[nH]cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)c12 CHEMBL439973 IC50 1000.0 nM
CN(Cc1cnc2[nH]c(N)nc(=O)c2n1)c1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1 CHEMBL158990 Ki 1000.0 nM
CCc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Br)cc1 CHEMBL371666 IC50 1000.0 nM
Cc1sc2nc(N)[nH]c(=O)c2c1Sc1cc(Cl)cc(Cl)c1 CHEMBL492839 IC50 1000.0 nM
NC(=O)c1ccc(C(=O)O)c(NC(=O)c2ccc(Cc3c[nH]c4nc(N)[nH]c(=O)c34)cc2)c1 CHEMBL4454174 IC50 1000.0 nM