O=C(NC1CN2CCC1CC2)c1cc2cc(Cl)cc(-c3ccccc3OCCF)c2o1 CHEMBL5182897 EC50 0.02 nM
CCCCOc1ccccc1-c1cccc2cc(C(=O)NC3CN4CCC3CC4)oc12 CHEMBL5170109 EC50 0.021 nM
O=C(Nc1ccc2cnccc2n1)c1cc2cccc(-c3ccccc3OCC(F)(F)F)c2o1 CHEMBL5191157 EC50 0.023 nM
CCCOc1ccccc1-c1cccc2cc(C(=O)NC3CN4CCC3CC4)oc12 CHEMBL5177098 EC50 0.044 nM
CC(C)Oc1ccc(C#N)cc1-c1cc(Cl)cc2cc(C(=O)N[C@H]3C[C@@H](O)C3)oc12 CHEMBL5195638 EC50 0.044 nM
N#Cc1ccc(Cl)c(-c2cccc3cc(C(=O)N[C@H]4CC[C@@H](O)C4)oc23)c1 CHEMBL5197108 EC50 0.047 nM
COc1ncc(-c2nn(C(=O)N3CCN4CCC3CC4)c3c2C[C@@H]2C[C@H]32)cc1Cl CHEMBL5415069 EC50 0.1 nM
O=C(N1CCN2CCC1CC2)n1nc(-c2ccc(F)cc2)c2c1[C@H]1C[C@H]1C2 CHEMBL5414358 EC50 0.1 nM
O=C(N1CCN2CCC1CC2)n1nc(-c2ccc(F)cc2)c2c1CC1CC21 CHEMBL5418636 EC50 0.1 nM
O=C(N1CCN2CCC1CC2)n1nc(-n2cc(C(F)(F)F)cn2)c2c1[C@H]1C[C@H]1C2 CHEMBL5286071 EC50 0.1 nM
COc1ccc(-n2nc(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1C(F)(F)F CHEMBL5413252 EC50 0.1 nM
O=C(c1nn(-c2ccc(Cl)c(Cl)c2)c2c1CCC2)N1CCN2CCC1CC2 CHEMBL5426863 EC50 0.1 nM
COc1ccc(-c2nn(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1 CHEMBL5408662 EC50 0.2 nM
Cc1ccc(-c2nn(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1 CHEMBL5395933 EC50 0.2 nM
CN1CCN(C(=O)[C@@H](COCc2ccc3c(c2)OCCO3)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911818 IC50 0.3 nM
COc1ccc(-n2nc(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1Cl CHEMBL5398714 EC50 0.3 nM
Cc1ccc(-n2nc(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1Cl CHEMBL5431661 EC50 0.3 nM
COc1ccc(-n2nc(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1C CHEMBL5420341 EC50 0.4 nM
Cc1nnc(-c2ccc(-c3c(F)c(F)cc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5415209 IC50 0.9 nM
COc1ccc(-n2nc(C(=O)N3CCN4CCC3CC4)c3c2CCC3)cc1F CHEMBL5406074 EC50 0.9 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911817 IC50 1.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-c2ccc(F)c(Cl)c2)c2c1COCC2 CHEMBL5290844 IC50 1.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-n2cc(C(F)(F)F)cn2)c2c1COCC2 CHEMBL5275403 IC50 1.7 nM
Cc1nnc(-c2ccc(-c3c(F)ccc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5425600 IC50 1.8 nM
Cc1cc(Cl)ccc1Oc1ncccc1C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCN(C)CC1 CHEMBL1911816 IC50 2.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(Cl)cc2Cl)CC1 CHEMBL1911815 IC50 2.0 nM
CCCCCCCCC(=O)N[C@@H](CN1CCCC1)[C@H](O)c1ccc2c(c1)OCCO2 CHEMBL1911678 IC50 2.0 nM
CCCCCCCC(=O)N[C@@H](CN1CCCC1)[C@H](O)c1ccc2c(c1)OCCO2 CHEMBL1911679 IC50 2.0 nM
CN1CCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163821 IC50 2.0 nM
NC1C[C@H]2CC[C@@H](C1)N2C(=O)[C@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 CHEMBL2163825 IC50 2.0 nM
NC1C[C@H]2CC[C@@H](C1)N2C(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)C1(c2ccc(OC(F)(F)F)cc2)CC1 CHEMBL2163828 IC50 2.0 nM
CN(C)CCN(C)C(=O)[C@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 CHEMBL2163838 IC50 2.0 nM
Cc1nnc(-c2ccc(-c3cc(F)cc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5411678 IC50 2.1 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(F)c1 CHEMBL3354637 IC50 2.5 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cc(F)cnc2Oc2ccc(Cl)cc2Cl)CC1 CHEMBL1911814 IC50 3.0 nM
CN1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163833 IC50 3.0 nM
NC1C[C@H]2CC[C@@H](C1)N2C(=O)[C@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(OC(F)(F)F)cc2)CC1 CHEMBL2163827 IC50 3.0 nM
NC1C[C@H]2CC[C@@H](C1)N2C(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 CHEMBL2163826 IC50 3.0 nM
NC1CCN(C(=O)[C@H](Cc2ccc(Br)cc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163823 IC50 3.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccccc2c1 CHEMBL3354022 IC50 3.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccc3cccc4ccc1c2c34 CHEMBL3354024 IC50 3.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccccc2c1 CHEMBL3354035 IC50 3.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc2ccc3cccc4ccc1c2c34 CHEMBL3354037 IC50 3.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1C(F)(F)F CHEMBL3354634 IC50 3.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(C(F)(F)F)c1 CHEMBL3354635 IC50 3.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C4(C)COC4)nc3-c3ccccc3OCC(F)(F)F)C2=O)cc1 CHEMBL5181454 IC50 3.6 nM
O=C(N[C@H](COCc1ccccc1)C(=O)N[C@@H]1CN2CCC1CC2)c1cccnc1Oc1ccc(C(F)(F)F)cc1Cl CHEMBL1911829 IC50 4.0 nM
CN1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2Cl)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163832 IC50 4.0 nM
CN(C)CCN(C)C(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 CHEMBL2163839 IC50 4.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C4(C)COC4)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5197585 IC50 4.3 nM
CC(C)(O)c1ccc(NC(=O)c2ccnn(-c3ccccc3OCC(F)(F)F)c2=O)cc1 CHEMBL5085509 EC50 4.4 nM
CN[C@@H]1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C1 CHEMBL1911827 IC50 5.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1F CHEMBL3354636 IC50 5.0 nM
Cc1nnc(-c2ccc(-c3c(F)cc(F)c4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5395864 IC50 5.6 nM
Cc1cc2c(c(-c3ccccc3OCC(F)(F)F)n1)CN(c1ccc(C(C)(C)O)cc1)C2=O CHEMBL5178033 IC50 5.9 nM
CN1CCN(C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163829 IC50 6.0 nM
O=C(c1nn(-c2ccc(F)c(Cl)c2)c2c1COCC2)N1CCN2CCC1CC2 CHEMBL5291288 IC50 6.0 nM
Cc1nnc(-c2ccc(-c3c(F)c(F)cc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5433486 IC50 6.8 nM
CN1CCN(C(=O)[C@@H](COCc2ccc(F)cc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911819 IC50 7.0 nM
O=C(N[C@H](COCc1ccccc1)C(=O)N[C@H]1CN2CCC1CC2)c1cccnc1Oc1ccc(C(F)(F)F)cc1Cl CHEMBL1911830 IC50 7.0 nM
CN1CCN(C(=O)[C@H](Cc2ccc(Br)cc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163834 IC50 7.0 nM
COc1ccc(-n2nc(C(=O)N3CCN4CCC3CC4)c3c2CCOC3)cc1 CHEMBL5277419 IC50 7.0 nM
CN1Cc2cc(-c3c(F)c(F)cc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)ccc2C1=O CHEMBL5395985 IC50 7.3 nM
Cc1nnc(-c2ccc(-c3cc(F)c(F)c4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5409280 IC50 7.3 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C(C)(C)F)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5193757 IC50 7.4 nM
CC(C)(O)c1ccc(N2Cc3c(ccnc3-c3ccc(F)cc3OCC(F)(F)F)C2=O)cc1 CHEMBL5078078 EC50 7.6 nM
Cc1nnc(-c2ccc(-c3cccc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5400263 IC50 7.8 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1 CHEMBL3354038 IC50 8.0 nM
CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)c1ccc2c(c1)OCCO2 CHEMBL1087641 IC50 9.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C(F)F)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5198393 IC50 9.2 nM
CN(C)[C@@H]1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C1 CHEMBL1911826 IC50 10.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C4CCCOC4)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5185934 IC50 10.0 nM
Cc1cc2c(c(-c3ccccc3OCC(F)F)n1)CN(c1ccc(C(C)(C)O)cc1)C2=O CHEMBL5182659 IC50 11.0 nM
CC(C)(NC(=O)O[C@@H]1CN2CCC1CC2)c1csc(-c2ccc(F)cc2)n1 CHEMBL4297611 IC50 12.0 nM
CC(C)(O)c1ccc(N2Cc3c(ccnc3-c3ccccc3OCC(F)(F)F)C2=O)cc1 CHEMBL5183525 IC50 13.0 nM
Cc1nnc(-c2ccc(-c3ccc(F)c4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)cc2)o1 CHEMBL5403767 IC50 14.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCC(F)(F)COCc1ccc(-c2ccccc2)cc1 CHEMBL3354633 IC50 15.0 nM
CN1Cc2cc(-c3c(F)ccc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)ccc2C1=O CHEMBL5398133 IC50 15.0 nM
NC1CCCC(NC(=O)[C@H](Cc2ccc(Cl)cc2Cl)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)C1 CHEMBL2163824 IC50 16.0 nM
CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)c1ccc2c(c1)OCCO2 CHEMBL2110588 IC50 16.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C(C)(C)O)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5186203 IC50 16.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C4CCOCC4)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5185095 IC50 16.0 nM
CC(C)(C#N)c1ccc(N2Cc3c(ccnc3-c3ccc(F)cc3OCC(F)(F)F)C2=O)cc1 CHEMBL5092141 IC50 17.0 nM
Cc1nnc(-c2ccc(-c3c(F)ccc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5398126 IC50 18.0 nM
CC(C)(O)c1ccc(NC(=O)c2cccn(-c3ccccc3OCC(F)(F)F)c2=O)cc1 CHEMBL5083428 IC50 19.0 nM
Cc1ncc(COC[C@@H](NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C(=O)N2CCN(C)CC2)o1 CHEMBL1911820 IC50 20.0 nM
C[C@@H]1CN(C(=O)[C@H](Cc2ccc(Cl)cc2Cl)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CCN1 CHEMBL2163836 IC50 20.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 CHEMBL3354052 IC50 20.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1 CHEMBL3354053 IC50 20.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CC(F)(F)CCCOCc1ccc(-c2ccccc2)cc1 CHEMBL3354632 IC50 20.0 nM
Cc1nnc(-c2ccc(-c3cc(F)cc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5430388 IC50 20.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-c2ccc(C(F)(F)F)cc2)c2c1COCC2 CHEMBL5273314 IC50 21.0 nM
CC(C)(O)c1ccc(N2Cc3c(cc(C4CCCCC4)nc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5186505 IC50 22.0 nM
Cc1ccccc1-c1ccc(COCCCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)cc1 CHEMBL3354041 IC50 25.0 nM
COc1ccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)cc1 CHEMBL3354042 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(F)cc2)cc1 CHEMBL3354048 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2cccc(F)c2)cc1 CHEMBL3354049 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL3354051 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc3c(c2)OCO3)cc1 CHEMBL3354054 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc3c(c2)OCCCO3)cc1 CHEMBL3354056 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1F CHEMBL3354624 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(F)c1 CHEMBL3354625 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1C(F)(F)F CHEMBL3354626 IC50 25.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)c(C(F)(F)F)c1 CHEMBL3354627 IC50 25.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccccc1-c1ccccc1 CHEMBL3354630 IC50 25.0 nM
Cc1nnc(-c2ccc(-c3c(F)cc(F)c4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5424264 IC50 29.0 nM
C[C@@H](OCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1CO)c1ccc(-c2ccccc2)cc1 CHEMBL3354629 IC50 30.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(Cl)cc2)CC1 CHEMBL1911680 IC50 32.0 nM
CC1(C)Cc2c(c(-c3ccc(F)cc3)nn2C(=O)N2CCN3CCC2CC3)CO1 CHEMBL5288633 IC50 32.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-n2cc(C(F)(F)F)cn2)c2c1CCOC2 CHEMBL5278676 IC50 32.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-n2cc(C(F)(F)F)cn2)c2c1CCC2 CHEMBL5286066 IC50 32.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-c2ccc(F)cc2)c2c1COCC2 CHEMBL5272946 IC50 34.0 nM
COc1ccc(-c2nn(C(=O)N3CCN4CCC3CC4)c3c2CCOC3)cc1 CHEMBL5278405 IC50 35.0 nM
O=C(N1CCN2CCC1CC2)n1nc(-n2cc(Cl)cn2)c2c1COCC2 CHEMBL5278640 IC50 37.0 nM
CN(C)C1CN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C1 CHEMBL1911825 IC50 40.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc3c(c2)OCCO3)cc1 CHEMBL3354055 IC50 40.0 nM
C[C@H](OCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1CO)c1ccc(-c2ccccc2)cc1 CHEMBL3354628 IC50 40.0 nM
CC(C)(O)COc1ccc(N2Cc3c(ccnc3-c3ccc(F)cc3OCC(F)(F)F)C2=O)cc1 CHEMBL5077442 IC50 40.0 nM
CN1Cc2cc(-c3cccc4c3C(=O)N([C@H](C3CC3)C(C)(C)O)C4)ccc2C1=O CHEMBL5394721 IC50 44.0 nM
CC(C)(O)c1ccc(NC(=O)c2cccc(-c3ccccc3OCC(F)(F)F)c2F)cc1 CHEMBL5086168 IC50 45.0 nM
Cc1nnc(-c2ccc(-c3cccc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5439954 IC50 48.0 nM
O=C1c2ccnc(-c3ccc(F)cc3OC(F)(F)F)c2CN1c1ccc(F)cc1 CHEMBL5091974 IC50 49.0 nM
CC(C)(O)c1ccc(NC(=O)c2ccnn(-c3ccc(F)cc3OCC(F)(F)F)c2=O)cc1 CHEMBL5086523 IC50 49.0 nM
CN1CCN(C(=O)[C@@H](COCC2(C)CC2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911824 IC50 50.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccnc(Cl)c2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911822 IC50 50.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1 CHEMBL3354025 IC50 50.0 nM
COc1ccccc1-c1ccc(COCCCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)cc1 CHEMBL3354044 IC50 50.0 nM
N#Cc1cccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)c1 CHEMBL3354046 IC50 50.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccccc1-c1ccccc1 CHEMBL3354062 IC50 50.0 nM
CN1Cc2cc(-c3cc(F)cc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)ccc2C1=O CHEMBL5431731 IC50 50.0 nM
Cc1ccc(Oc2ncccc2C(=O)N[C@H](COCc2ccccc2)C(=O)N2CCN(C)CC2)cc1 CHEMBL1911682 IC50 53.0 nM
CC(C)(O)c1ccc(N2Cc3c(ccnc3-c3ccccc3OCC(F)F)C2=O)cc1 CHEMBL5200972 IC50 53.0 nM
Cc1nnc(-c2ccc(-c3cc(F)c(F)c4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5406871 IC50 54.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCC(F)(F)COCc1ccc(-c2ccccc2)cc1 CHEMBL3354621 IC50 60.0 nM
C[C@@H](OCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccc(-c2ccccc2)cc1 CHEMBL3354623 IC50 60.0 nM
CN[C@H]1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C1 CHEMBL1911828 IC50 65.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC1CCCCC1 CHEMBL3354026 IC50 70.0 nM
C[C@H](OCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1ccc(-c2ccccc2)cc1 CHEMBL3354622 IC50 70.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1cccc(-c2ccccc2)c1 CHEMBL3354631 IC50 70.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2F)cc1 CHEMBL3354050 IC50 75.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1cccc(-c2ccccc2)c1 CHEMBL3354063 IC50 75.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC1C2CC3CC(C2)CC1C3 CHEMBL3354032 IC50 80.0 nM
COc1ccc(-n2nc(C(=O)N3CCNCC(CO)C3)c3c2CCOC3)cc1 CHEMBL5273405 IC50 85.0 nM
CCCCCCCCCCCCCCCC(=O)NC(CN1CCCC1)C(O)c1ccc(O)cc1 CHEMBL34780 IC50 90.0 nM
CCCCCCCCCCCCCCCC(=O)NC(CN1CCCC1)C(O)c1ccc2c(c1)OCCO2 CHEMBL34778 IC50 90.0 nM
Cc1ccc(C(=O)N[C@H](COCc2ccccc2)C(=O)N2CCN(C)CC2)c(Oc2ccc(Cl)cc2)n1 CHEMBL1911811 IC50 90.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL574645 IC50 90.0 nM
CN1CCN(C(=O)[C@H](COCc2ccccc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163830 IC50 90.0 nM
COc1ccccc1-c1nccc2c1CN(c1ccc(C)cc1)C2=O CHEMBL5076612 IC50 97.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL1086996 IC50 100.0 nM
Cc1ccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)cc1 CHEMBL3354039 IC50 100.0 nM
Cc1cccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)c1 CHEMBL3354040 IC50 100.0 nM
OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cc1 CHEMBL3354638 IC50 100.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cc(Br)cnc2Oc2ccc(Cl)cc2)CC1 CHEMBL1911812 IC50 110.0 nM
CN1CCN(C(=O)[C@@H](COCC(C)(C)C)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911823 IC50 120.0 nM
CN1Cc2cc(-c3cccc4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)ccc2C1=O CHEMBL5407795 IC50 130.0 nM
O=C([C@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1)N1CCNCC1 CHEMBL2163835 IC50 150.0 nM
COc1cccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)c1 CHEMBL3354043 IC50 150.0 nM
N#Cc1ccc(-c2ccc(COCCCCCN3C[C@H](O)[C@@H](O)[C@H](O)[C@H]3CO)cc2)cc1 CHEMBL3354045 IC50 150.0 nM
N#Cc1ccccc1-c1ccc(COCCCCCN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)cc1 CHEMBL3354047 IC50 150.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccnc(F)c2)cc1 CHEMBL3354060 IC50 150.0 nM
CN1CCN(C(=O)[C@H](Cc2ccccc2)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL2163831 IC50 160.0 nM
Cc1nnc(-c2ccc(-c3ccc(F)c4c3C(=O)N([C@@H](C(C)(C)O)C(F)(F)F)C4)cc2)o1 CHEMBL5431537 IC50 167.0 nM
CC(C)(O)c1ccc(NC(=O)c2cccc(-c3ccccc3OCC(F)(F)F)n2)cc1 CHEMBL5091003 IC50 170.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cc(F)cnc2Oc2ccc(Cl)cc2)CC1 CHEMBL1911813 IC50 180.0 nM
COc1ccc(-n2nc(C(=O)N3CCCN(C)CC3)c3c2CCOC3)cc1 CHEMBL5270537 IC50 180.0 nM
C[C@H]1CN(C(=O)[C@H](Cc2ccc(Cl)cc2Cl)NC(=O)C2(c3ccc(Cl)cc3Cl)CC2)CCN1 CHEMBL2163837 IC50 190.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccccc1 CHEMBL3354034 IC50 200.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccccc2)cn1 CHEMBL3354064 IC50 200.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(F)cc2F)CC1 CHEMBL1911685 IC50 230.0 nM
OC[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL3354029 IC50 250.0 nM
CN(C)C(=O)c1cc2c(c(-c3ccccc3OCC(F)F)n1)CN(c1ccc(C(C)(C)O)cc1)C2=O CHEMBL5192371 IC50 250.0 nM
O=C([C@H](Cc1ccc(Br)cc1)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1)N1CCC(O)CC1 CHEMBL2163822 IC50 260.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccncc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 CHEMBL1911821 IC50 275.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(F)cc2)CC1 CHEMBL1911684 IC50 300.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL3354016 IC50 300.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC1C2CC3CC(C2)CC1C3 CHEMBL3354019 IC50 300.0 nM
CN1CCN(C(=O)[C@@H](COCc2ccccc2)NC(=O)c2cccnc2Oc2c(Cl)cccc2Cl)CC1 CHEMBL1911686 IC50 340.0 nM
O=C(CCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1CO)NC12CC3CC(CC(C3)C1)C2 CHEMBL3354027 IC50 400.0 nM
CCOc1ccccc1C(=O)Nc1cccc2c1C(=O)N(CC1CC1)C2 CHEMBL5427019 IC50 482.0 nM
OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC12CC3CC(CC(C3)C1)C2 CHEMBL1088158 IC50 500.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCC1CCCCC1 CHEMBL3354014 IC50 500.0 nM
CS(=O)(=O)c1ccc(N2Cc3c(ccnc3-c3ccc(F)cc3OCC(F)(F)F)C2=O)cc1 CHEMBL5089984 IC50 630.0 nM
COc1ccc(-n2nc(C(=O)N3CCCNCC3)c3c2CCOC3)cc1 CHEMBL5281181 IC50 690.0 nM
CN(C)C(=O)c1ccc(N2Cc3c(ccnc3-c3ccc(F)cc3OCC(F)(F)F)C2=O)cc1 CHEMBL5081829 IC50 700.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccccc1 CHEMBL3354021 IC50 750.0 nM
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCOCc1ccc(-c2ccc(F)nc2)cc1 CHEMBL3354061 IC50 750.0 nM
O=C(CCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)NC12CC3CC(CC(C3)C1)C2 CHEMBL2170199 IC50 1000.0 nM
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCN5C[C@H](O)[C@@H](O)[C@H](O)[C@H]5CO)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3354018 IC50 1000.0 nM
CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OCCCCCN5C[C@H](O)[C@@H](O)[C@H](O)[C@@H]5CO)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3354031 IC50 1000.0 nM
COc1ccccc1-c1nccc2c1CN(c1ccc(F)cc1)C2=O CHEMBL5088946 IC50 1000.0 nM