COc1ccc(Oc2c(C)n[nH]c2-c2ccc(O)cc2O)cc1 CHEMBL1468579 Potency 0.1 nM
O=c1cnc2cnc(N3CCOCC3)nc2n1Cc1cccs1 CHEMBL1395605 Potency 6.3 nM
COc1ccc(C(=O)N2CCC3(CC2)CN(CC(C)C)C3)cc1 CHEMBL1437213 Potency 7.9 nM
Cn1cc(-c2nc3cncnc3n(Cc3ccc(F)cc3)c2=O)c2ccccc21 CHEMBL1323897 Potency 15.8 nM
CC(C)NC(=O)N1CC[C@@]2(CCCN(C(=O)Oc3ccccc3)C2)C1 CHEMBL1314723 Potency 20.0 nM
Cc1noc(C)c1C(=O)N1CCC2(CCN(Cc3ccc(C#N)cc3)CC2)CC1 CHEMBL1608984 Potency 31.6 nM
CN1CCN(c2ncc3nc(-c4ccccc4)c(=O)n(C4CC4)c3n2)CC1 CHEMBL1475207 Potency 31.6 nM
O=C(Nc1cccc(F)c1)N1CC[C@@]2(CCCN(C(=O)c3cccc(F)c3)C2)C1 CHEMBL1394223 Potency 39.8 nM
COc1ccc(Cn2c(C)nc3c(c2=O)c2nc4ccccc4nc2n3Cc2ccco2)cc1 CHEMBL1575586 Potency 100.0 nM
Cc1noc(C)c1-c1nccc(N2CCN(C)CC2)n1 CHEMBL1367789 Potency 125.9 nM
COCCn1c(=O)c(CCc2ccccc2)nc2cnc(N3CCOCC3)nc21 CHEMBL1559404 Potency 158.5 nM
COc1ccc(CNc2ncncc2-c2ccccc2C(F)(F)F)c(OC)c1 CHEMBL489943 Potency 158.5 nM
CCN(CC)c1ccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc2c1 CHEMBL374632 Potency 199.5 nM
CCCCn1c(SCc2cc(=O)n3ccsc3n2)nc2cc(C(=O)OC)ccc2c1=O CHEMBL1465204 Potency 199.5 nM
COc1ccc(S(=O)(=O)N2CCN(c3ncnc4c(-c5ccccc5)nsc34)CC2)cc1 CHEMBL1558999 Potency 251.2 nM
CCCSc1nc(C)c(-c2csc(C(C#N)=C3CCCC3)n2)cc1C#N CHEMBL1597805 Potency 251.2 nM
Cc1cc(=O)n2c3c(cccc13)CCC2 CHEMBL1306484 Potency 251.2 nM
CCOc1ccc(OCC)c(NC(=O)CSc2nc3cccnc3n2C)c1 CHEMBL1364519 Potency 251.2 nM
Cc1nc2cnc(Nc3ccccc3)nc2n(Cc2ccc(F)cc2)c1=O CHEMBL1338051 Potency 251.2 nM
COc1cccc(Cn2c(=O)c(-c3ccc(F)cc3)nc3cnc(N4CCOCC4)nc32)c1 CHEMBL1484120 Potency 251.2 nM
O=C(c1cnccn1)N1CCC2(CC1)CN(c1ccncc1)C2 CHEMBL1474503 Potency 251.2 nM
CCOc1ccc(NC(=O)CCC(=O)NNS(=O)(=O)c2ccccc2[N+](=O)[O-])cc1 CHEMBL1560196 Potency 281.8 nM
O=C(O)COc1ccccc1/C=N/NC(=O)CSc1nnc(SCc2cccc3ccccc23)s1 CHEMBL3197156 Potency 316.2 nM
Oc1c(I)cc(I)c2cccnc12 CHEMBL86754 Potency 316.2 nM
CCNc1ncc2nc(-c3cccs3)c(=O)n(-c3ccc(OC)cc3)c2n1 CHEMBL1475686 Potency 316.2 nM
CCOC(=O)c1c(NC(=O)C2CCN(S(=O)(=O)c3cccs3)CC2)sc(C)c1C CHEMBL1524600 Potency 316.2 nM
COc1ccc(CNc2cc(-c3cccc(C#N)c3)ncn2)c(OC)c1 CHEMBL1447663 Potency 398.1 nM
O=C(O)c1ccccc1C(=O)NCc1cccnc1 CHEMBL1379269 Potency 398.1 nM
Cn1c(=O)c(-c2cccs2)nc2cnc(N3CCOCC3)nc21 CHEMBL1477247 Potency 398.1 nM
CCNc1ncc2nc(-c3ccccc3)c(=O)n(Cc3ccc(F)cc3)c2n1 CHEMBL1593545 Potency 398.1 nM
CN1C(=O)/C(=N\CCO)c2c3ccccc3c(O)c3cccc1c23 CHEMBL1724937 Potency 398.1 nM
C/C=C/C(=O)N1CC2(CC(c3cccc(NC(=O)CC(c4ccccc4)c4ccccc4)c3)=NO2)C[C@H]1C(N)=O CHEMBL1583747 Potency 446.7 nM
Cc1ccccc1NC(=O)Cn1c(NCC(C)O)nc2ccccc21 CHEMBL1341658 Potency 501.2 nM
CCCCC(OC(=O)c1cc2occc2n1C)C(=O)NCC1CCCO1 CHEMBL1361346 Potency 501.2 nM
CCOc1ccc2[nH]c(=O)c(CN(CCc3ccccc3)C(=O)c3cnccn3)cc2c1 CHEMBL576544 Potency 501.2 nM
O=C1OCC2OC(O)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2-c2c(O)c(O)c3oc(=O)c4c(c(O)c(O)c5oc(=O)c2c3c54)-c2c1cc(O)c(O)c2O CHEMBL416615 Potency 501.2 nM
O=C1NC(=O)N(Cc2ccc(F)cc2)C(=O)/C1=C/NCCCn1ccnc1 CHEMBL1460582 Potency 501.2 nM
CCCCc1cc(=O)oc2cc(C)c(CN3CCCC3)c(O)c12 CHEMBL1471583 Potency 501.2 nM
COc1ccccc1CN1CC2(CCN(S(=O)(=O)c3ccccc3)CC2)C1 CHEMBL1441649 Potency 501.2 nM
Cc1cc2c(c(=O)o1)C1(C(=O)N(C)c3ccccc31)C(C#N)=C(N)O2 CHEMBL1304690 Potency 501.2 nM
Nc1c2ccccc2nc2ccccc12 CHEMBL1201038 Potency 501.2 nM
Cc1noc(C)c1CSc1nnc(-c2ccco2)o1 CHEMBL1599155 Potency 501.2 nM
COc1ccccc1NC(=O)Cn1cnc2c(cnn2-c2ccccc2)c1=O CHEMBL1325932 Potency 501.2 nM
OC(COc1ccc(Br)cc1)CN1CCOCC1 CHEMBL1326155 Potency 501.2 nM
CC[C@@H]1CN2CCc3cc(OC)c(OC)cc3[C@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc21 CHEMBL1515885 Potency 501.2 nM
Cn1c(=O)c(C(=S)NC(=O)C2CC2)c(N)n(Cc2ccccc2)c1=O CHEMBL1341609 Potency 501.2 nM
COCC(C)NC(=O)CCS(=O)(=O)c1nc(-c2ccc(OC)cc2)cc(C(F)(F)F)n1 CHEMBL1487321 Potency 501.2 nM
Fc1ccc(-c2nnn(Cc3nc4ccccc4s3)n2)cc1 CHEMBL1583734 Potency 562.3 nM
O=C(Oc1ccccc1)N1CCC2(CC1)CN(c1ncccn1)C2 CHEMBL1558420 Potency 631.0 nM
CCOc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)cc1OCC CHEMBL1334796 Potency 631.0 nM
CCCC(c1nnnn1Cc1ccco1)N1CCN(c2cc(Cl)ccc2C)CC1 CHEMBL1423898 Potency 631.0 nM
O=C(c1ccncc1)N1CCC2(CCN(Cc3nccs3)CC2)CC1 CHEMBL1481017 Potency 631.0 nM
CC(=O)N1CCN(c2ccc(OCC3CO[C@@](Cn4ccnc4)(c4ccc(Cl)cc4Cl)O3)cc2)CC1 CHEMBL1324508 Potency 631.0 nM
O=C(O)CN(CC(=O)O)Cc1cc2c(-c3ccccc3C(=O)O)c3cc(CN(CC(=O)O)CC(=O)O)c(=O)cc-3oc2cc1O CHEMBL1606751 Potency 631.0 nM
C[n+]1c2cc(N)ccc2cc2ccc(N)cc21 CHEMBL354349 Potency 631.0 nM
C[C@H]1[C@@H](O)[C@@H](C)/C=C\C=C/C=C\C=C/C=C\C=C/C=C\[C@@H](O[C@H]2O[C@@H](C)[C@@H](O)[C@@H](N)[C@@H]2O)C[C@@H]2O[C@](O)(C[C@@H](O)C[C@@H](O)[C@@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@H]1C)C[C@@H](O)[C@H]2C(=O)O CHEMBL1591426 Potency 631.0 nM
CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12 CHEMBL554190 Potency 631.0 nM
O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12 CHEMBL8260 Potency 631.0 nM
COC(=O)N1CCC2(CC1)CN(c1ccccc1)C2 CHEMBL1406936 Potency 631.0 nM
O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CCCN(c3ccncc3)C2)CC1 CHEMBL1519225 Potency 631.0 nM
CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1 CHEMBL388590 Potency 631.0 nM
NC(Cc1cc(O)c(O)cc1O)C(=O)O CHEMBL109037 Potency 656.1 nM
NC1=C(c2nc(O)c3ccccc3n2)C(=O)CN1CCc1ccccc1 CHEMBL1337644 Potency 794.3 nM
COCCCNCCCOc1ccc(C)cc1Br CHEMBL1371642 Potency 794.3 nM
Cc1ccc(-c2nn3c(C)nnc3s2)cc1NC(=O)c1ccc(-c2cccc(Cl)c2)o1 CHEMBL1352844 Potency 794.3 nM
O=C(OC1CCCCC1)c1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 CHEMBL1334684 Potency 794.3 nM
O=C(Oc1ccccc1)N1CCC2(CCCN(c3ccccc3)C2)CC1 CHEMBL1590919 Potency 794.3 nM
COc1cc(OC)cc(-c2nnc(Nc3nc4c(F)cccc4s3)o2)c1 CHEMBL473314 Potency 794.3 nM
COc1ccc(C(=O)N2CCC3(CCCN(c4ncccn4)C3)CC2)cc1 CHEMBL1434789 Potency 794.3 nM
CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 CHEMBL1014 Potency 794.3 nM
N#CCCn1c(=O)c(-c2cccs2)nc2cnc(N3CCOCC3)nc21 CHEMBL1517051 Potency 794.3 nM
O=C(c1ccco1)N1CCC[C@@]2(CCN(Cc3ccccc3)C2)C1 CHEMBL1330396 Potency 794.3 nM
CC[C@H]1NC(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N1 CHEMBL1457003 Potency 794.3 nM
CN(C)c1ncc2nc(-c3cccc(C#N)c3)c(=O)n(C[C@H]3CCCO3)c2n1 CHEMBL1517643 Potency 794.3 nM
CC(C)c1c(O)c(-c2cc3c(c(C(C)C)c2O)CCC2C(C)(C)CCC[C@@]32C)cc2c1CCC1C(C)(C)CCC[C@@]21C CHEMBL1354305 Potency 794.3 nM
Cc1nnc2sc(-c3ccc(NC(=O)c4ccc(-c5ccc(Cl)cc5Cl)o4)cc3)nn12 CHEMBL1350887 Potency 794.3 nM
CCN(CC)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)N1CCOCC1)cn2C CHEMBL1548978 Potency 794.3 nM
O=C(O)C[C@@H]1C(=O)O[C@@H]2C(COC(=O)c3cc(O)c(O)c(O)c3)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H]2OC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1391063 Potency 891.3 nM
CCCCc1ccc(/C=C2/C(=O)ON=C2c2ccccc2)s1 CHEMBL1448791 Potency 891.3 nM
CCN(CC)c1ccc2cc(-c3nnc(-c4ccccc4)o3)c(=O)oc2c1 CHEMBL1611002 Potency 891.3 nM