O=S(=O)(c1ccc2c(c1)OCCO2)N1Cc2cnc(C(O)c3cccc(N4CCNCC4)c3)cc2C1 CHEMBL5087604 IC50 1.0 nM
O=S(=O)(c1ccc(-n2cccn2)c(F)c1)N1Cc2cnc(C(O)c3cccc(N4CCNCC4)c3)cc2C1 CHEMBL5081543 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3cccc(N4CCNCC4)c3)cc2C1 CHEMBL5089843 IC50 1.0 nM
CN1CCN(c2cccc(C(O)c3cc4c(cn3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c2)CC1 CHEMBL5089941 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)c(F)c1)N1Cc2cnc(C(O)c3cccc(N4CCNCC4)c3)cc2C1 CHEMBL5093513 IC50 1.0 nM
Cc1c(C(O)c2ccccc2)ncc2c1CN(S(=O)(=O)c1ccc(-c3ncco3)cc1)C2 CHEMBL5076738 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3cccc4c3CNC4)cc2C1 CHEMBL5093019 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)c(F)c1)N1Cc2cnc(C(O)c3ccccc3)nc2C1 CHEMBL5070827 IC50 1.0 nM
CC(c1cccc(N2CCNCC2)c1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc(-c3ncco3)c(F)c1)C2 CHEMBL5074124 IC50 1.0 nM
COc1cccc(C(O)c2ncc3c(n2)CN(S(=O)(=O)c2ccc(-c4ncco4)c(F)c2)C3)c1 CHEMBL5084410 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)c(F)c1)N1Cc2cnc(C(O)c3cccc(N4CCNCC4)c3)nc2C1 CHEMBL5079020 IC50 1.0 nM
CN1CCN(c2cccc(C(O)c3ncc4c(n3)CN(S(=O)(=O)c3ccc(-c5ncco5)c(F)c3)C4)c2)CC1 CHEMBL5086426 IC50 1.0 nM
Cc1ccc(C(O)c2cc3c(cn2)CN(S(=O)(=O)c2ccc(-c4ncco4)cc2)C3)cc1N1CCN(C)CC1 CHEMBL5071051 IC50 1.0 nM
CC1CN(c2cccc(C(O)c3ncc4c(n3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c2)CCN1C CHEMBL5076417 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3cccc(N4CCN5CCCC5C4)c3)nc2C1 CHEMBL5080931 IC50 1.0 nM
CN1CCN(c2cccc(C(C#N)c3cc4c(cn3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c2)CC1 CHEMBL5090630 IC50 1.0 nM
CNCc1ccc2cccc(C(O)c3ncc4c(n3)CN(S(=O)(=O)c3ccc(-c5ncco5)c(F)c3)C4)c2n1 CHEMBL5088777 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)c(F)c1)N1Cc2cnc(C(O)c3cccc4c3OCCNC4)nc2C1 CHEMBL5074944 IC50 1.0 nM
CC1c2cnc(C(O)c3cccc(N4CCN(C)CC4)c3)cc2CN1S(=O)(=O)c1ccc(-c2ncco2)c(F)c1 CHEMBL5071991 IC50 1.0 nM
CC1c2cc(C(O)c3cccc(N4CCN(C)CC4)c3)ncc2CN1S(=O)(=O)c1ccc(-c2ncco2)c(F)c1 CHEMBL5078314 IC50 1.0 nM
CN1CC2CN(c3cccc(C(O)c4cc5c(cn4)CN(S(=O)(=O)c4ccc(-c6ncco6)c(F)c4)C5)c3)CC2C1 CHEMBL5082460 IC50 1.0 nM
CN1CC(Oc2cccc(C(O)c3cc4c(cn3)CN(S(=O)(=O)c3ccc(-c5ncco5)c(F)c3)C4)c2)C1 CHEMBL5075259 IC50 1.0 nM
CN1CC2=C(C1)CN(c1cccc(C(O)c3cc4c(cn3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c1)C2 CHEMBL5089140 IC50 1.0 nM
CN(C)C1CN(c2cccc([C@H](O)c3cc4c(cn3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c2)C1 CHEMBL5085499 IC50 1.0 nM
COC(c1cccc(N2CC(N(C)C)C2)c1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc(-c3ncco3)cc1)C2 CHEMBL5087360 IC50 1.0 nM
COC(c1cccc(OC2CCN(C)CC2)c1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc(-c3ncco3)cc1)C2 CHEMBL5076220 IC50 1.0 nM
Cc1nc(C(O)c2cccc(N3CCN(C)CC3)c2)nc2c1CN(S(=O)(=O)c1ccc(-c3ncco3)c(F)c1)C2 CHEMBL5075503 IC50 1.0 nM
CN1CC2(C1)CN(c1cccc(C(O)c3cc4c(cn3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c1)C2 CHEMBL5070846 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3cccc(N4CC5NCCOC5C4)c3)cc2C1 CHEMBL5071382 IC50 1.0 nM
Cc1ccc(C(O)c2cc3c(cn2)CN(S(=O)(=O)c2ccc(-c4ncco4)s2)C3)cc1N1CCN(C)CC1 CHEMBL5076545 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3cccc(N4CC5CCNC5C4)c3)cc2C1 CHEMBL5075632 IC50 1.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3cccc(N4CC5CC(C4)N5)c3)cc2C1 CHEMBL5083364 IC50 1.0 nM
CN1CCN(c2cccc(C(O)c3ncc4c(n3)CN(S(=O)(=O)c3ccc(-c5ncco5)cc3)C4)c2)CC1 CHEMBL5087937 IC50 1.0 nM
CN1CC2CN(c3cccc(C(O)c4cc5c(cn4)CN(S(=O)(=O)c4ccc(-c6ncco6)cc4)C5)c3)CC2C1 CHEMBL5077384 IC50 1.0 nM
CN1CCN(c2ccccc2C(O)c2cc3c(cn2)CN(S(=O)(=O)c2ccc(-c4ncco4)cc2)C3)CC1 CHEMBL5075420 IC50 1.0 nM
Cc1ccc(C(O)c2cc3c(cn2)CN(S(=O)(=O)c2ccc(NC(=O)C4CC4)cc2)C3)cc1N1CCN(C)CC1 CHEMBL5079385 IC50 1.0 nM
COc1nc(C(O)c2cccc(N3CCN(C)CC3)c2)nc2c1CN(S(=O)(=O)c1ccc(-c3ncco3)cc1)C2 CHEMBL5077487 IC50 1.0 nM
CN1CC2(C1)CN(c1cccc(C(O)c3cc4c(cn3)CN(S(=O)(=O)c3ccc5ccccc5c3)C4)c1)C2 CHEMBL5078625 IC50 1.0 nM
O=C(C(O)c1ccc2c(c1)NCCO2)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5090564 IC50 1.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)cccc2s1 CHEMBL5077695 IC50 1.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)cccc2o1 CHEMBL5072669 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(OC)c1 CHEMBL5071913 IC50 1.0 nM
CCc1cccc(C(CNC)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)c1 CHEMBL5076148 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(C2CC2)c1 CHEMBL5075117 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(OC2CC2)c1 CHEMBL5077308 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)cc(Cl)c1 CHEMBL5072768 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)cc(OC)c1 CHEMBL5077098 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2cccnc12 CHEMBL5072962 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(C)ccc1F CHEMBL5083615 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(F)cc(Cl)c1 CHEMBL5082668 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(Cl)c1F CHEMBL5085846 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)ccc1OC CHEMBL5076633 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(OC2CC2)c(Cl)c1 CHEMBL5080794 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(F)c(Cl)c1OC CHEMBL5089710 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)c(F)c(OC)c1 CHEMBL5077948 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(C)c(F)cc1OC CHEMBL5081547 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(C)c(OC)cc1F CHEMBL5084457 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)c(C)cc1OC CHEMBL5081719 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(C)c(OC)cc1C CHEMBL5078583 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(C)c(F)cc1C CHEMBL5093527 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(C)c(OC2CCC2)c1 CHEMBL5092051 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2nsnc12 CHEMBL5075195 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(C)c2nsnc12 CHEMBL5090107 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccn2cc(C)nc12 CHEMBL5080754 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)c(F)cc1OC CHEMBL5079272 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2oc(C)nc12 CHEMBL5080468 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(F)c2sc(C)nc12 CHEMBL5069812 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(F)c(F)c(Cl)c1 CHEMBL5081023 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(F)c(F)c(C2CC2)c1 CHEMBL5081887 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(OC)ccc1F CHEMBL5073081 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(OC(F)F)c1 CHEMBL5091508 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(C(F)F)c1 CHEMBL5083824 IC50 1.0 nM
CNC[C@H](C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(Cl)c1 CHEMBL5078007 IC50 1.0 nM
CNCCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(Cl)c1 CHEMBL5078672 IC50 1.0 nM
CNCCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)cc(Cl)c1 CHEMBL5075096 IC50 1.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2sc(C)nc12 CHEMBL5077832 IC50 1.0 nM
CN1CCc2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c2C1 CHEMBL5077550 IC50 1.0 nM
CN(C)CCOC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(Cl)c1 CHEMBL5077892 IC50 1.0 nM
CN1CCN(c2cccc(C(O)C(=S)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c2)CC1 CHEMBL5093412 IC50 1.0 nM
CN1CC2=C(C1)CN(c1cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c1)C2 CHEMBL5090319 IC50 1.0 nM
CN(C)CC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5088452 IC50 1.0 nM
CN1CC2CN(c3cccc(C(O)C(=O)N4CC5=C(C4)CN(S(=O)(=O)c4ccc6c(c4)OCCO6)C5)c3)CC2C1 CHEMBL5070602 IC50 1.0 nM
O=C(C(O)c1cccc2c1CN(C1CC1)C2)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5074929 IC50 1.0 nM
O=C(C(c1cccc(Cl)c1)C1CCCN1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5080985 IC50 1.0 nM
NCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5077527 IC50 1.0 nM
CN1CCc2c(cccc2C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)C1 CHEMBL5086674 IC50 1.0 nM
CNCC(C(=O)N1Cc2cn(S(=O)(=O)c3ccc4c(c3)OCCO4)cc2C1)c1cccc2sc(C)nc12 CHEMBL5077523 IC50 1.0 nM
CN1CC(Oc2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c2)C1 CHEMBL5086372 IC50 1.0 nM
Cc1nc2c(C(CN3CCC3)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)cccc2s1 CHEMBL5074008 IC50 1.0 nM
CN1CCOc2ccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)cc21 CHEMBL5078104 IC50 1.0 nM
[2H]C1([2H])Oc2ccc(S(=O)(=O)N3CC4=C(CN(C(=O)C(O)c5cccc6oc(C)nc56)C4)C3)cc2OC1([2H])[2H] CHEMBL5069484 IC50 1.0 nM
O=C(C(OC1CN(CCO)C1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5077103 IC50 1.0 nM
CN1CC2CN(c3cccc(C(O)C(=O)N4CC5=C(C4)CN(S(=O)(=O)c4ccc6c(c4)OCCO6)C5)c3)CC2(F)C1 CHEMBL5074846 IC50 1.0 nM
O=C(C(O)c1cccc(N2CCNCC2)c1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5081035 IC50 1.0 nM
CN1CCN(c2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5ccoc5c3)C4)c2)CC1 CHEMBL5080036 IC50 1.0 nM
CN(C)CCOc1cc(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)ccc1F CHEMBL5085377 IC50 1.0 nM
CN(C)CCOc1ccc(F)c(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)c1 CHEMBL5074423 IC50 1.0 nM
O=C(C(O)c1cccc(N2CC3CNCC(C2)C3(F)F)c1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5081196 IC50 1.0 nM
O=C(C(O)c1cccc2[nH]ncc12)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5080410 IC50 50.0 nM
O=C([C@@H](O)c1ccc2c(c1)NCCO2)N1Cc2cn(S(=O)(=O)c3ccc4c(c3)OCCO4)nc2C1 CHEMBL5070494 IC50 50.0 nM
O=C([C@@H](O)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5083436 IC50 50.0 nM
Cc1cccc(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2cnc4c(c2)OCCO4)C3)c1 CHEMBL5082541 IC50 50.0 nM
CC(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1noc2ccccc12 CHEMBL5077177 IC50 50.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3cnc5c(c3)OCCO5)C4)cccc2o1 CHEMBL5080067 IC50 50.0 nM
O=C(C(O)c1cccc2cccnc12)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5085759 IC50 50.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3cnc5c(c3)OCCO5)C4)cccc2s1 CHEMBL5072412 IC50 50.0 nM
O=C(C(O)c1ccnc(N2CCOCC2)c1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5084455 IC50 50.0 nM
O=C(C(O)c1noc2ccccc12)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5070841 IC50 50.0 nM
Cn1c(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2cnc4c(c2)OCCO4)C3)cc2ccccc21 CHEMBL5070752 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(OC)c(C2CC2)c1 CHEMBL5084691 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(Cl)ccc1F CHEMBL5075079 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc(F)c(Cl)c1 CHEMBL5087902 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1csc(C2CC2)n1 CHEMBL5090034 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2ccnn12 CHEMBL5077037 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(F)c(F)c(OC)c1 CHEMBL5073760 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(OC)cc2sc(C)nc12 CHEMBL5085840 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(F)c(OC)c(Cl)c1 CHEMBL5080327 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(C(F)(F)F)c1 CHEMBL5090177 IC50 50.0 nM
CNCC(C(=O)N1Cc2cn(S(=O)(=O)c3ccc4c(c3)OCCO4)cc2C1)c1cc(C)c(F)cc1OC CHEMBL5084548 IC50 50.0 nM
CNCC(F)(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(Cl)c1 CHEMBL5074150 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)C1CCCC1C CHEMBL5071990 IC50 50.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5093097 IC50 50.0 nM
CN1Cc2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c2C1 CHEMBL5085159 IC50 50.0 nM
CN1CC(OC(C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)c2ccccc2)C1 CHEMBL5081116 IC50 50.0 nM
CN1Cc2c(F)ccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c2C1 CHEMBL5080662 IC50 50.0 nM
O=C(C(O)c1cccc2c1CN(C1COC1)C2)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5077911 IC50 50.0 nM
O=C(C(OC1CNC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5093431 IC50 50.0 nM
CNCC(C(=O)N1Cc2cn(S(=O)(=O)c3ccc4c(c3)OCCO4)cc2C1)c1cccc(Cl)c1 CHEMBL5076496 IC50 50.0 nM
CNCCOC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(F)c(F)c(Cl)c1 CHEMBL5083530 IC50 50.0 nM
O=C(N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)C1(c2ccccc2)CCNC1 CHEMBL5078820 IC50 50.0 nM
O=C([C@@H](O)c1cccc2c1CNC2)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5085283 IC50 50.0 nM
COc1ccc(F)cc1C(CN(C)C)C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5086443 IC50 50.0 nM
CC(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(Cl)c1 CHEMBL5084607 IC50 50.0 nM
O=C(C(CN1CCC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5091014 IC50 50.0 nM
O=C(C(CN1CC(O)C1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5076386 IC50 50.0 nM
COCCOC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(OC(F)F)c1 CHEMBL5089742 IC50 50.0 nM
O=C(C(O)c1n[nH]c2ccccc12)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5074140 IC50 50.0 nM
O=C(C(O)c1cccc2c1CCO2)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5070234 IC50 50.0 nM
CC(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2oc(C)nc12 CHEMBL5077721 IC50 50.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3cc(F)c5c(c3)OCCO5)C4)cccc2o1 CHEMBL5077571 IC50 50.0 nM
O=C(C(OCC1(F)CNC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5081271 IC50 50.0 nM
NC(=O)NCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5078962 IC50 50.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5ccoc5c3)C4)cccc2o1 CHEMBL5076455 IC50 50.0 nM
O=C(C(O)c1cccc(N2CCOCC2)c1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5094918 IC50 50.0 nM
O=C(C(O)c1cccc(N2CCNC(C(F)F)C2)c1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5076726 IC50 50.0 nM
CC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc(N2CCNCC2)c1 CHEMBL5082729 IC50 50.0 nM
O=C(C(O)c1cccc(N2CCN(C3CC3)CC2)c1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5080523 IC50 50.0 nM
O=C(C(O)c1cccc2c1OCC2)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5077306 IC50 50.0 nM
O=C(C(CNCC1CCCC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5094550 IC50 50.0 nM
O=C(C(CNCC1CCC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5076231 IC50 50.0 nM
O=C(C(CNCC1CCOCC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5073245 IC50 50.0 nM
CCNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5089107 IC50 50.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1Cc2ccc(C(O)c3ccccc3)cc2C1 CHEMBL5076621 IC50 100.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1Cc2cnc(C(O)c3ccccc3)cc2C1 CHEMBL5081877 IC50 100.0 nM
CNCC(c1ccccc1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5088986 IC50 100.0 nM
O=S(=O)(c1ccc2c(c1)OCCO2)N1Cc2cnc(C(O)c3cccc(Cl)c3)cc2C1 CHEMBL5093224 IC50 100.0 nM
CNCCC(c1ccccc1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5085352 IC50 100.0 nM
NC(c1ccccc1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5088857 IC50 100.0 nM
CNC(c1ccccc1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5072947 IC50 100.0 nM
CNCC(c1ccccc1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc(-n3cccn3)c(F)c1)C2 CHEMBL5081875 IC50 100.0 nM
CNCCC(c1ccccc1)c1cc2c(cn1)CN(S(=O)(=O)c1ccc(-n3cccn3)c(F)c1)C2 CHEMBL5081731 IC50 100.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)c3ccccc3)cc2C1 CHEMBL5090926 IC50 100.0 nM
O=S(=O)(c1ccc(-n2nccc2F)cc1)N1Cc2cnc(C(O)c3ccccc3)cc2C1 CHEMBL5089261 IC50 100.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cc(C(O)c3ccccc3)nnc2C1 CHEMBL5091869 IC50 100.0 nM
CNC(=O)C(c1cccc(OC)c1)c1ncc2c(n1)CN(S(=O)(=O)c1ccc(-c3ncco3)cc1)C2 CHEMBL5080156 IC50 100.0 nM
COc1ccc2cc(S(=O)(=O)N3Cc4cnc(C(O)c5cccc(N6CC7(CN(C)C7)C6)c5)cc4C3)ccc2c1 CHEMBL5074156 IC50 100.0 nM
Cc1nc2c(C(O)C(=O)N3Cc4cn(S(=O)(=O)c5cnc6c(c5)OCCO6)cc4C3)cccc2o1 CHEMBL5081006 IC50 200.0 nM
O=C([C@@H](O)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5094952 IC50 200.0 nM
COc1cccc([C@H](O)C(=O)N2Cc3cn(S(=O)(=O)c4ccc5c(c4)OCCO5)nc3C2)c1 CHEMBL5084205 IC50 200.0 nM
O=C([C@@H](O)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1cc(F)c3c(c1)OCCO3)C2 CHEMBL5076452 IC50 200.0 nM
O=C(C(c1ccccc1)N1CCCC1=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5078529 IC50 200.0 nM
CCc1nc(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)cs1 CHEMBL5083677 IC50 200.0 nM
O=C(C(O)c1cccc(Cl)n1)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5080587 IC50 200.0 nM
O=C(C(O)c1cccc2ncccc12)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5090644 IC50 200.0 nM
Cc1nc2c(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OC(F)(F)C(F)(F)O5)C4)cccc2o1 CHEMBL5088916 IC50 200.0 nM
Cn1nc(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4c(c2)OCCO4)C3)c2cc(F)ccc21 CHEMBL5075950 IC50 200.0 nM
O=C([C@@H](O)c1ccccc1)N1Cc2cn(S(=O)(=O)c3ccc4c(c3)OCCO4)cc2C1 CHEMBL5090484 IC50 200.0 nM
O=C(Cc1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5083001 IC50 200.0 nM
O=C(C(O)c1ccc2c(c1)CCO2)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5089097 IC50 200.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2sc(C(=O)N(C)C)nc12 CHEMBL5079338 IC50 200.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cccc2nc(C)nn12 CHEMBL5077667 IC50 200.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)C1CCCCC1 CHEMBL5094457 IC50 200.0 nM
CNCC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1cc(C)cn2ccnc12 CHEMBL5089444 IC50 200.0 nM
NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5074243 IC50 200.0 nM
CC(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccc2c(c1)NCCO2 CHEMBL5083920 IC50 200.0 nM
O=C(C(CN1CC(F)C1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5088286 IC50 200.0 nM
O=C(C(CN1CCCC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5084304 IC50 200.0 nM
O=C(C(CN1CCOCC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5077757 IC50 200.0 nM
CNC(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5073609 IC50 200.0 nM
O=C(C(CNC1COC1)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5077071 IC50 200.0 nM
Cc1ccc(F)c(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2cnc4c(c2)OCCO4)C3)c1 CHEMBL5088896 IC50 200.0 nM
Cc1noc2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c12 CHEMBL5084252 IC50 200.0 nM
O=C(C(O)c1noc2ccccc12)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5078160 IC50 200.0 nM
CC(O)(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5083843 IC50 200.0 nM
CC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5083747 IC50 200.0 nM
[2H]C1([2H])Oc2cc(S(=O)(=O)N3CC4=C(CN(C(=O)C(O)c5cccc6oc(C)nc56)C4)C3)cnc2OC1([2H])[2H] CHEMBL5084588 IC50 200.0 nM
CS(=O)(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5094678 IC50 200.0 nM
CC(C)(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5087415 IC50 200.0 nM
CC(C)OC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5086497 IC50 200.0 nM
COC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5082006 IC50 200.0 nM
O=C(N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)C1(c2ccccc2)CC1 CHEMBL5076012 IC50 200.0 nM
O=C(C(c1ccccc1)C1CC1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5070790 IC50 200.0 nM
CN1CCN(c2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)OCCO5)C4)c2)CC1 CHEMBL5091714 IC50 200.0 nM
CN1CCN(c2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5nccnc5c3)C4)c2)CC1 CHEMBL5090702 IC50 200.0 nM
CN1CCN(c2cccc(C(O)C(=O)N3CC4=C(C3)CN(S(=O)(=O)c3ccc5c(c3)N(C)CCO5)C4)c2)CC1 CHEMBL5092636 IC50 200.0 nM
COCCN(C)c1cccc(C(O)C(=O)N2CC3=C(C2)CN(S(=O)(=O)c2ccc4scnc4c2)C3)c1 CHEMBL5093145 IC50 200.0 nM
CC(=O)NC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2)c1ccccc1 CHEMBL5091786 IC50 200.0 nM
COC(C(=O)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2)c1cccc2oc(C)nc12 CHEMBL5091315 IC50 200.0 nM
O=C(C(O)c1cccc(N2CCC3(CC2)COC3)c1)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5090074 IC50 200.0 nM
N=S(=O)(c1ccc2c(c1)OCCO2)N1CC2=C(CN(C(=O)[C@@H](O)c3ccccc3)C2)C1 CHEMBL5093538 IC50 200.0 nM
O=C(C(CO)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1ccc3c(c1)OCCO3)C2 CHEMBL5094749 IC50 200.0 nM
O=C([C@@H](CO)c1ccccc1)N1CC2=C(C1)CN(S(=O)(=O)c1cnc3c(c1)OCCO3)C2 CHEMBL5080690 IC50 200.0 nM
O=S(=O)(C1CCC(n2cccn2)CC1)N1Cc2cnc(C(O)c3ccccc3)cc2C1 CHEMBL5085277 IC50 1000.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)C3CCCC3)nc2C1 CHEMBL5069413 IC50 1000.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cnc(C(O)C3CCCCC3)nc2C1 CHEMBL5091102 IC50 1000.0 nM
O=S(=O)(c1ccc(C2=NCCO2)cc1)N1Cc2cnc(C(O)c3ccccc3)cc2C1 CHEMBL5069860 IC50 1000.0 nM
O=S(=O)(c1ccc(-c2ncco2)cc1)N1Cc2cc(C(O)c3ccccc3)[n+]([O-])cc2C1 CHEMBL5075618 IC50 1000.0 nM