CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(F)c1 CHEMBL5420815 IC50 0.35 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(Cl)c1 CHEMBL5414874 IC50 0.36 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccc(F)cc1 CHEMBL5423427 IC50 1.34 nM
Cc1ccc(COc2ccc(-c3ncc[nH]3)cc2NC(=O)C#Cc2ccccc2)cc1 CHEMBL5431792 IC50 3.65 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCC1CC1 CHEMBL5420985 IC50 4.39 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3747448 IC50 6.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1C#CCNC(C)C CHEMBL4450581 IC50 7.0 nM
Cc1cc(OCc2cnc(SC3CCCC3)n2-c2cccnc2)ccc1C#CCCNC(C)C CHEMBL5206855 IC50 7.0 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCc1ccc(C(F)(F)F)cc1 CHEMBL5402707 IC50 7.19 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCC1CCCC1 CHEMBL5428666 IC50 7.36 nM
CN1CCC(NC(=O)OCC#Cc2cc(F)c(OCc3nnc(SC4C=CCCC4)n3-c3cccnc3)cc2F)CC1 CHEMBL5416704 IC50 7.9 nM
[2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(Sc2ncc(COc3cc(F)c(C#CCOC(=O)NC4CCN(C)CC4)cc3F)n2-c2cccnc2)C1([2H])[2H] CHEMBL4476693 IC50 8.0 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCCN1CCOCC1 CHEMBL5430557 IC50 8.07 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCCCN1CCOCC1 CHEMBL5396390 IC50 8.39 nM
CCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5405131 IC50 8.5 nM
[2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(Sc2nnc(COc3cc(F)c(C#CCOC(=O)NC4CCN(C)CC4)cc3F)n2-c2cccnc2)C1([2H])[2H] CHEMBL5407869 IC50 9.7 nM
CC(C)Oc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5412755 IC50 10.68 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL3747513 IC50 11.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 CHEMBL2311578 IC50 11.0 nM
CN1CCC(NC(=O)OCC#Cc2c(F)cc(OCc3nnc(SC4C=CCCC4)n3-c3cccnc3)cc2F)CC1 CHEMBL5399073 IC50 11.0 nM
CN1CCC(NC(=O)OCC#Cc2cc(F)c(OCc3nnc(S[C@H]4C=CCCC4)n3-c3cccnc3)cc2F)CC1 CHEMBL5441034 IC50 12.0 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(Br)c1 CHEMBL5423222 IC50 12.09 nM
CN(C)c1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5400122 IC50 12.8 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccc(Cl)cc1 CHEMBL5402810 IC50 13.86 nM
CCCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5415375 IC50 14.1 nM
COc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5417192 IC50 14.61 nM
Cc1cc2c(-c3nnn[nH]3)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3746179 IC50 15.0 nM
CN1CCC(NC(=O)OCC#Cc2cc(F)c(OCc3nnc(S[C@@H]4C=CCCC4)n3-c3cccnc3)cc2F)CC1 CHEMBL5397160 IC50 15.0 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(OC)c1 CHEMBL5439553 IC50 15.52 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1F CHEMBL5410189 IC50 15.9 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccc(Cl)cc1F CHEMBL5428726 IC50 16.64 nM
CN1CCC(NC(=O)OCC#Cc2ccc(OCc3nnc(SC4C=CCCC4)n3-c3cccnc3)c(F)c2F)CC1 CHEMBL5419713 IC50 17.0 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1F CHEMBL5410787 IC50 17.8 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(O)c1 CHEMBL5401866 IC50 18.57 nM
C#CCNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4555451 Ki(app) 18.6 nM
COCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5422395 IC50 19.24 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCC1CCCCC1 CHEMBL5433632 IC50 19.67 nM
CN1CCN(C2(CNC3CCN(c4cccc(-c5cc6cc(F)ccc6[nH]5)c4)CC3)CCC2)CC1 CHEMBL4280801 IC50 20.0 nM
CC(C)N1CCN(CCNC2CCN(c3cccc(-c4cc5cc(F)ccc5[nH]4)c3)CC2)CC1 CHEMBL4280125 IC50 20.0 nM
CN1CCN(CCNC(=O)OCC#Cc2ccc(OCc3nnc(SC4C=CCCC4)n3-c3cccnc3)cc2F)CC1 CHEMBL5402777 IC50 20.0 nM
CCC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4553677 Ki(app) 20.8 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCOC(=O)NCCN1CCN(C)CC1 CHEMBL5414510 IC50 21.0 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1Cl CHEMBL5425652 IC50 22.78 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCOC2 CHEMBL3747049 IC50 23.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCOC(=O)NC1CCN(C)CC1 CHEMBL5426088 IC50 23.0 nM
Cc1cc2c(C(=O)NCCC#N)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4535337 Ki(app) 24.1 nM
C#CCCNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4441270 Ki(app) 24.5 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(S(N)(=O)=O)cc1 CHEMBL2315422 IC50 25.0 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncc[nH]2)ccc1OCC1CCC1 CHEMBL5430775 IC50 25.63 nM
C=CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5189708 IC50 26.0 nM
C=CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4453010 Ki(app) 26.6 nM
CCCC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4551165 Ki(app) 26.9 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361184 IC50 27.0 nM
Cc1cc2c(C(=O)NCC#N)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4543206 Ki(app) 28.1 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(C(F)(F)F)c1 CHEMBL5427428 IC50 28.65 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCOC(=O)N1CCN(C)CC1 CHEMBL5409286 IC50 29.0 nM
C#CCNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4463657 Ki(app) 30.6 nM
CCONC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5192118 IC50 31.0 nM
C=CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4580172 Ki(app) 31.4 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1ncc(OC)c(NCc2cccc(B(O)O)c2)n1 CHEMBL4846448 IC50 32.0 nM
CCC(=O)NCC#Cc1ccc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)cc1C CHEMBL5413736 IC50 32.0 nM
O=C(C#Cc1ccccc1)Nc1cccc(-c2ncc[nH]2)c1 CHEMBL5436721 IC50 32.27 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4460205 Ki(app) 32.3 nM
C#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4438398 Ki(app) 32.8 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4459139 Ki(app) 33.2 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 CHEMBL5399688 IC50 34.0 nM
Cc1cc2c(NS(=O)(=O)C3CC3)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4451017 IC50 34.6 nM
Cc1cc2c(C(=N)NO)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5175854 IC50 35.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCNS(C)(=O)=O CHEMBL5404554 IC50 35.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(Nc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361185 IC50 36.0 nM
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4461505 IC50 36.4 nM
CC#CCNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4463689 Ki(app) 37.3 nM
C#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4558932 Ki(app) 37.9 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3747647 IC50 40.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCO CHEMBL5426808 IC50 40.0 nM
CCCNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4446356 Ki(app) 40.8 nM
NC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315430 IC50 41.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCNC1CCN(C)CC1 CHEMBL5419453 IC50 41.0 nM
CNC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315431 IC50 42.0 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cccc(C)c1 CHEMBL5435725 IC50 42.39 nM
CC#CCNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4535642 Ki(app) 42.4 nM
CONC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315427 IC50 43.0 nM
COc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3696924 IC50 43.0 nM
CCC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL4456523 Ki(app) 43.0 nM
CC(C)N1CCN(CCNC2CCN(c3cccc(-c4cc5cc(C#N)ccc5[nH]4)c3)CC2)CC1 CHEMBL4445673 IC50 44.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCN2 CHEMBL5184848 IC50 44.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCN CHEMBL5409495 IC50 44.0 nM
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCCC2 CHEMBL4862740 IC50 45.6 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3F)n2)CC1 CHEMBL3361210 IC50 46.0 nM
Cc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3696915 IC50 47.0 nM
[2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(Sc2nnc(COc3ccc(-c4ccc(S(C)(=O)=O)cc4)c(C)c3)n2-c2cccnc2)C1([2H])[2H] CHEMBL5412023 IC50 47.0 nM
O=C(CO)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315428 IC50 48.0 nM
CONC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5199985 IC50 48.0 nM
Cc1cc2c(NC(=O)c3ccco3)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5184774 IC50 49.0 nM
CC(C)N1CCN(CCNC2CCN(c3cccc(-c4cc5cc([N+](=O)[O-])ccc5[nH]4)c3)CC2)CC1 CHEMBL3787674 IC50 50.0 nM
CC(C)N1CCC(NC2CCN(c3cccc(-c4cc5cc(F)ccc5[nH]4)c3)CC2)CC1 CHEMBL4288865 IC50 50.0 nM
CC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2C)cc1 CHEMBL2315424 IC50 53.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5180155 IC50 53.0 nM
CNC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2C)cc1 CHEMBL2315423 IC50 54.0 nM
CONC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL5205850 IC50 54.0 nM
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4871978 IC50 54.7 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCNC(C)C CHEMBL5414204 IC50 55.0 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1cc(OC)c(OC)c(OC)c1 CHEMBL5415803 IC50 55.64 nM
Cc1cc2c(NC(=O)c3ccco3)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4858461 IC50 57.3 nM
CONC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2C)cc1 CHEMBL2315421 IC50 58.0 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4854511 IC50 58.6 nM
CC(=O)Nc1ccc(-c2cc(NCc3ccccc3)nc(NC[C@H]3CC[C@H](C(N)=O)CC3)n2)cc1 CHEMBL3361216 IC50 59.0 nM
CCOCCOc1ccc(-c2ncc[nH]2)cc1NC(=O)C#Cc1ccccc1 CHEMBL5397031 IC50 59.3 nM
Nc1ccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)cc1[N+](=O)[O-] CHEMBL3361178 IC50 60.0 nM
Cc1cc(OCc2nnc(SC3CCCCC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 CHEMBL5400436 IC50 60.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3cc4ccccc4o3)n2)CC1 CHEMBL3361223 IC50 61.0 nM
CS(=O)(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315432 IC50 63.0 nM
CC(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315433 IC50 65.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(C=O)cc1 CHEMBL2315425 IC50 67.0 nM
OCc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3696925 IC50 68.0 nM
Oc1ccc(Nc2nc(-c3ccc(Cl)cc3)cs2)cc1 CHEMBL1076555 IC50 70.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(C#N)cc1 CHEMBL2315420 IC50 71.0 nM
NS(=O)(=O)c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315429 IC50 71.0 nM
Fc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1Cl CHEMBL2315450 IC50 71.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccc4[nH]ncc4c3)n2)CC1 CHEMBL3361224 IC50 71.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCNC2 CHEMBL3745888 IC50 71.0 nM
CCONC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL5198263 IC50 72.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3csc4ccccc34)n2)CC1 CHEMBL3361225 IC50 74.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCNS(=O)(=O)c1ccc(F)cc1 CHEMBL5433131 IC50 74.0 nM
COc1nc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3746353 IC50 76.0 nM
Nc1ccc(Nc2nc(-c3ccc(Cl)cc3)cs2)cc1 CHEMBL1080890 IC50 80.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccc4[nH]ccc4c3)n2)CC1 CHEMBL3361226 IC50 82.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCCC2 CHEMBL4455739 IC50 82.8 nM
CC(=O)c1cccc(-c2cc(NCc3ccccc3)nc(NC[C@H]3CC[C@H](C(N)=O)CC3)n2)c1 CHEMBL3361211 IC50 87.0 nM
N#Cc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315451 IC50 88.0 nM
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc(NCc2cccc(B(O)O)c2)c2ccccc2n1 CHEMBL4876550 IC50 88.9 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccc(CO)cc3)n2)CC1 CHEMBL3361217 IC50 89.0 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCCC2 CHEMBL4872975 IC50 89.8 nM
Oc1ccc(Nc2nc(-c3cccs3)cs2)cc1 CHEMBL1081262 EC50 90.0 nM
Clc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1Cl CHEMBL2315452 IC50 90.0 nM
CC(C)N1CCN(C2(CNC3CCN(c4cccc(-c5cc6cc(F)ccc6[nH]5)c4)CC3)COC2)CC1 CHEMBL4277404 IC50 90.0 nM
Oc1ccc(Nc2ncc(-c3ccccc3)o2)cc1 CHEMBL1076570 IC50 91.0 nM
Cc1cc2c(NC(=O)c3ccco3)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)COCC2 CHEMBL4871208 IC50 91.0 nM
C#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4848009 IC50 91.4 nM
Cc1cc2c(NC(=O)c3ccco3)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCCC2 CHEMBL4859176 IC50 93.4 nM
Cc1cc2c(C(=O)O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3746650 IC50 95.0 nM
C/C=C/C(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5176940 IC50 96.0 nM
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5175776 IC50 97.0 nM
COc1cnc(-n2c(C)cc3c(NC(=O)c4ccco4)cccc32)nc1NCc1cccc(B(O)O)c1 CHEMBL4847081 IC50 97.4 nM
Cc1nc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3747498 IC50 98.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1Br CHEMBL2315453 IC50 100.0 nM
CC(C)N1CCN(C2(CNC3CCN(c4cccc(-c5cc6cc(F)ccc6[nH]5)c4)CC3)CCC2)CC1 CHEMBL4291440 IC50 100.0 nM
Cc1cc2c(NS(=O)(=O)C(F)(F)F)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4573319 IC50 100.9 nM
CC(=O)c1ccc(-c2cc(NCc3ccccc3)nc(NC[C@H]3CC[C@H](C(N)=O)CC3)n2)cc1 CHEMBL3361218 IC50 102.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccc(Cl)cc3)n2)CC1 CHEMBL3361219 IC50 106.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3cccc(O)c3)n2)CC1 CHEMBL3361212 IC50 106.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3cccnc3)n2)CC1 CHEMBL3361227 IC50 109.0 nM
COc1cccc2c(NCc3ccccc3)nc(-n3c(N)nc4ccccc43)nc12 CHEMBL3746912 IC50 110.0 nM
O=Cc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315434 IC50 112.0 nM
Nc1ccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)cc1 CHEMBL3361177 IC50 112.0 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc(NCc2cccc(B(O)O)c2)c2ccccc2n1 CHEMBL4864700 IC50 113.7 nM
CS(=O)(=O)c1cccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)c1 CHEMBL3360670 IC50 116.0 nM
CC#CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)COCC2 CHEMBL4877447 IC50 117.0 nM
Cc1cc2c(NS(C)(=O)=O)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)COCC2 CHEMBL4858094 IC50 117.2 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCCCC2 CHEMBL4439188 IC50 119.7 nM
Oc1ccc(Nc2nc(-c3cccc(O)c3)cs2)cc1 CHEMBL1081626 IC50 120.0 nM
COc1ccccc1-c1cnc(Nc2ccc(O)cc2)o1 CHEMBL1081994 IC50 120.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361188 IC50 127.0 nM
CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4530376 IC50 129.4 nM
Oc1ccc(Nc2ncc(-c3ccc(N4CCOCC4)cc3)o2)cc1 CHEMBL1082184 IC50 130.0 nM
CS(=O)(=O)NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361190 IC50 133.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc(C)c1Cl CHEMBL2315454 IC50 134.0 nM
Cc1cc2c(NS(=O)(=O)c3ccccc3)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4461462 IC50 134.9 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3cccc(CO)c3)n2)CC1 CHEMBL3361213 IC50 135.0 nM
Oc1ccc(Nc2ncc(-c3cccc(Cl)c3)o2)cc1 CHEMBL1082173 IC50 140.0 nM
Clc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315444 IC50 140.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccccc3F)n2)CC1 CHEMBL3360663 IC50 141.0 nM
Cc1cc2c(C#N)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3746000 IC50 144.0 nM
COc1cccc2c(NCc3ccccc3)nc(-n3c(OC)nc4ccccc43)nc12 CHEMBL3696863 IC50 145.0 nM
COc1cccc(-c2cc(NCc3ccccc3)nc(NC[C@H]3CC[C@H](C(N)=O)CC3)n2)c1 CHEMBL3352905 IC50 149.0 nM
Cc1[nH]c2ccccc2c1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3747075 IC50 149.0 nM
Cc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1Cl CHEMBL2315455 IC50 150.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccc4[nH]ccc4c3)n2)CC1 CHEMBL3361179 IC50 150.0 nM
Cc1cc(OCc2nnc(SC3C=CCCC3)n2-c2cccnc2)ccc1C#CCNC(=O)OC(C)(C)C CHEMBL5415233 IC50 150.0 nM
COc1cccc2c(NCc3ccccc3)nc(-n3c(C)nc4ccccc43)nc12 CHEMBL3696861 IC50 152.0 nM
NCc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3696917 IC50 153.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nc2c(c(NCc3cccc(N)c3)n1)CCC2 CHEMBL5207852 IC50 154.0 nM
CC(C)N1CCN(CCNC2CCN(c3cccc(-c4cc5ccccc5[nH]4)c3)CC2)CC1 CHEMBL4280546 IC50 160.0 nM
Cc1cc2c(C(N)=O)cccc2n1-c1nccc(NCc2ccccc2)n1 CHEMBL4581661 IC50 160.9 nM
O=[N+]([O-])c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315435 IC50 162.0 nM
Cc1cc2c(NC(=O)c3ccco3)cccc2n1-c1nc(NCc2cccc(B(O)O)c2)c2ccccc2n1 CHEMBL4847502 IC50 162.1 nM
C/C=C/C(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4878519 IC50 166.2 nM
Brc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315445 IC50 168.0 nM
COc1cccc(-c2cnc(Nc3ccc(O)cc3)o2)c1 CHEMBL1082174 IC50 170.0 nM
COc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315436 IC50 172.0 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2nccs2)ccc1F CHEMBL5412356 IC50 172.2 nM
N#Cc1ccc(-c2csc(Nc3ccc(O)cc3)n2)cc1 CHEMBL1081627 IC50 180.0 nM
COc1nc2ccccc2n1-c1nc(NCc2ccccc2)c2ncsc2n1 CHEMBL3696873 IC50 180.0 nM
CC(C)N1CCC(N[C@H]2CC[C@H](c3cccc(-c4cc5cc(F)ccc5[nH]4)c3)CC2)CC1 CHEMBL4278176 IC50 180.0 nM
Cc1cccc(-c2cc(NCc3ccccc3)nc(NC[C@H]3CC[C@H](C(N)=O)CC3)n2)c1 CHEMBL3361214 IC50 183.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1Cl CHEMBL2315456 IC50 184.0 nM
Cc1cc2c(NC(=O)c3cccs3)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5174989 IC50 185.0 nM
Oc1ccc(Nc2nc(-c3ccccc3)cs2)cc1 CHEMBL562493 IC50 190.0 nM
O=C(O)c1cccc(-c2cnc(Nc3ccc(O)cc3)o2)c1 CHEMBL1082175 IC50 190.0 nM
CC(C)N1CCN(C(=O)CCNC2CCN(c3cccc(-c4cc5cc(F)ccc5[nH]4)c3)CC2)CC1 CHEMBL4276697 IC50 190.0 nM
Cc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3696896 IC50 192.0 nM
C=CC(=O)Nc1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4859015 IC50 192.4 nM
Cc1cc2c(C(N)=S)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4468726 IC50 192.6 nM
CCN1CCN(CCNC2CCN(c3cccc(-c4cc5ccccc5[nH]4)c3)CC2)CC1 CHEMBL4291849 IC50 200.0 nM
Cc1ccc(C(=O)C#Cc2ccccc2)cc1 CHEMBL4763993 IC50(app) 200.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3cccc([N+](=O)[O-])c3)n2)CC1 CHEMBL3360671 IC50 201.0 nM
CC(C)(C)N1CCN(CCNC2CCN(c3cccc(-c4cc5ccccc5[nH]4)c3)CC2)CC1 CHEMBL4288427 IC50 210.0 nM
CNC(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3747639 IC50 215.0 nM
Cc1cc2c(NC(=O)c3cscn3)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5197225 IC50 216.0 nM
Cc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315447 IC50 220.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccc(Cl)cc3)n2)CC1 CHEMBL3361173 IC50 221.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccc(C(F)(F)F)cc3)n2)CC1 CHEMBL3361220 IC50 222.0 nM
Fc1cc(Br)cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315457 IC50 225.0 nM
COc1cccc2c(NCc3ccccc3)nc(-n3c(N(C)C)nc4ccccc43)nc12 CHEMBL3696879 IC50 227.0 nM
Oc1ccc(Nc2nc(-c3ccccn3)cs2)cc1 CHEMBL579212 IC50 230.0 nM
CCN(CC)c1ccc(-c2cnc(Nc3ccc(O)cc3)o2)cc1 CHEMBL1082029 IC50 230.0 nM
CNc1nc2ccccc2n1-c1nc(NCc2ccccc2)c2cccc(OC)c2n1 CHEMBL3696878 IC50 233.0 nM
Cc1cc2c(C(=N)N)cccc2n1-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5169705 IC50 233.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3cccc(C(F)(F)F)c3)n2)CC1 CHEMBL3361215 IC50 237.0 nM
Cc1ccc2[nH]c(-c3cccc(N4CCC(NCCN5CCN(C(C)C)CC5)CC4)c3)cc2c1 CHEMBL3785307 IC50 240.0 nM
Cc1cc2c(NC(=O)c3ccno3)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4877750 IC50 241.4 nM
CCOc1ccc(-c2cc(NCc3ccccc3)nc(NC[C@H]3CC[C@H](C(N)=O)CC3)n2)cc1 CHEMBL3361221 IC50 246.0 nM
Cc1nc2ccccn2c1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3746787 IC50 248.0 nM
Clc1cc(Cl)cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315458 IC50 257.0 nM
Cc1cc2c(NC(=O)CCl)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4852198 IC50 258.4 nM
Nc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315437 IC50 262.0 nM
O=C(NS(=O)(=O)C(F)(F)F)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361191 IC50 264.0 nM
Clc1cccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315809 IC50 279.0 nM
CN1CCN(CCNC2CCN(c3cccc(-c4cc5ccccc5[nH]4)c3)CC2)CC1 CHEMBL4283987 IC50 280.0 nM
Brc1cccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315810 IC50 283.0 nM
O=C(C#Cc1ccccc1)Nc1cc(-c2ncccn2)ccc1F CHEMBL5410404 IC50 283.27 nM
Oc1ccc(Nc2nc(-c3ccncc3)cs2)cc1 CHEMBL565257 IC50 290.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccc(F)cc3)n2)CC1 CHEMBL3361222 IC50 299.0 nM
Oc1ccc(Nc2nc(-c3cccnc3)cs2)cc1 CHEMBL373909 IC50 300.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3360661 IC50 300.0 nM
Cc1cc(OCc2nnc(SC3CCC(F)(F)CC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 CHEMBL5398304 IC50 300.0 nM
COCCOc1cccc2c(NCc3ccccc3)nc(-n3c(C)nc4ccccc43)nc12 CHEMBL3746988 IC50 304.0 nM
Cc1cc2c(NC(=O)CCl)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4576017 IC50 308.1 nM
Cc1cc(OCc2nnc(SC3CCCC=C3F)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 CHEMBL5422339 IC50 320.0 nM
Oc1ccc(Nc2ncc(-c3ccc(Cl)cc3)o2)cc1 CHEMBL1076585 IC50 330.0 nM
c1cc(-c2cc3ccccc3[nH]2)cc(N2CCC(NCCN3CCNCC3)CC2)c1 CHEMBL4293387 IC50 330.0 nM
Cc1cc2c(F)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3745805 IC50 342.0 nM
Oc1ccc(Nc2nc(-c3ccccc3F)cs2)cc1 CHEMBL1081276 IC50 360.0 nM
COc1cccc(-c2ccc(F)c(NC(=O)C#Cc3ccccc3)c2)c1 CHEMBL5394493 IC50 363.07 nM
Cc1nn2ccccc2c1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3746833 IC50 367.0 nM
COCCOc1cccc2c(NCc3ccccc3)nc(-n3c(OC)nc4ccccc43)nc12 CHEMBL3696920 IC50 370.0 nM
O=C(CCl)Nc1cccc(NC2=NS(=O)(=O)c3ccccc32)c1 CHEMBL3220939 IC50 370.0 nM
COc1cccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315443 IC50 375.0 nM
CC(=O)c1ccccc1-c1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315416 IC50 379.0 nM
Fc1cccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315811 IC50 379.0 nM
CC(C)N1CCN(CCCNC2CCN(c3cccc(-c4cc5ccccc5[nH]4)c3)CC2)CC1 CHEMBL4290763 IC50 380.0 nM
Cc1cc2c(NC(=O)/C=C/CN(C)C)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4473427 IC50 387.1 nM
Nc1nc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3746037 IC50 425.0 nM
Oc1ccc(Nc2nc(-c3ccc(Cl)c(Cl)c3)cs2)cc1 CHEMBL1081482 IC50 430.0 nM
Cc1cc2c(NC(=O)CCCl)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4854688 IC50 436.2 nM
Brc1ccc(OCc2nnc(SC3CCCC3)n2-c2ccccc2)cc1 CHEMBL2315800 IC50 440.0 nM
Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1F CHEMBL2315426 IC50 443.0 nM
CCc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3696916 IC50 445.0 nM
Cc1cc2c(NC(=O)/C=C/c3ccccc3)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4584967 IC50 447.2 nM
CNC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361189 IC50 448.0 nM
Cc1cc2c(NC(=O)CN3CCCC3)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4555198 IC50 448.7 nM
CC(=O)c1cccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)c1 CHEMBL2315418 IC50 451.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccsc3)n2)CC1 CHEMBL3361228 IC50 452.0 nM
Cc1cc(OCc2nnc(SC3CCOCC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 CHEMBL5399682 IC50 460.0 nM
Cc1cc2c(NC(=O)c3cscn3)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4870059 IC50 468.3 nM
c1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315792 IC50 470.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3cccc(F)c3)cc(-c3ccccc3)n2)CC1 CHEMBL3361199 IC50 474.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3cccc(Cl)c3)n2)CC1 CHEMBL3360668 IC50 483.0 nM
NC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccoc3)n2)CC1 CHEMBL3361229 IC50 491.0 nM
Cc1cc2cc(NC(=O)c3cccnc3N)ccc2[nH]1 CHEMBL4799933 IC50 500.0 nM
Brc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315438 IC50 523.0 nM
Cc1cccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL2315441 IC50 524.0 nM
N#Cc1ccccc1-c1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315415 IC50 536.0 nM
COc1cccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)c1 CHEMBL3360669 IC50 543.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3cccc(F)c3)n2)CC1 CHEMBL3360667 IC50 552.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccco3)n2)CC1 CHEMBL3361180 IC50 570.0 nM
Cc1ccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)cc1 CHEMBL3361171 IC50 577.0 nM
Cc1cccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)c1 CHEMBL3360666 IC50 578.0 nM
COc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315449 IC50 587.0 nM
C=CC(=O)Nc1ncnc2c1c(-c1ccccc1)nn2C(C)(C)C CHEMBL4762311 IC50(app) 600.0 nM
Fc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315446 IC50 604.0 nM
N#Cc1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 CHEMBL2315448 IC50 609.0 nM
Cc1cc2c(Cl)cccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3747140 IC50 632.0 nM
Cc1cccc2c1cc(C)n2-c1nc2c(c(NCc3ccccc3)n1)CNCC2 CHEMBL3747371 IC50 648.0 nM
FC(F)(F)c1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3747138 IC50 651.0 nM
COc1ccccc1-c1csc(Nc2ccc(O)cc2)n1 CHEMBL1081115 IC50 670.0 nM
Cc1ccccc1-c1cc(-c2ccccc2)nc(NC[C@H]2CC[C@H](C(=O)O)CC2)n1 CHEMBL3360662 IC50 673.0 nM
Fc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315439 IC50 683.0 nM
Cc1cc2c(NC(=O)CC#N)cccc2n1-c1nc2c(c(NCc3cccc(B(O)O)c3)n1)CCC2 CHEMBL4861682 IC50 692.3 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccccc3Cl)n2)CC1 CHEMBL3360664 IC50 700.0 nM
O=[N+]([O-])/C=C/c1cccnc1 CHEMBL4791813 IC50(app) 700.0 nM
COc1ccc2[nH]c(-c3cccc(N4CCC(NCCN5CCN(C(C)C)CC5)CC4)c3)cc2c1 CHEMBL3786444 IC50 710.0 nM
c1ccc(OCc2nnc(SC3CCCC3)n2-c2ccccc2)cc1 CHEMBL2315462 IC50 720.0 nM
Clc1cccc(-n2c(COc3ccccc3)nnc2SC2CCCC2)c1 CHEMBL2315782 IC50 740.0 nM
O=C(O)[C@H]1CC[C@H](CNc2nc(-c3ccccc3)cc(-c3ccc(F)cc3)n2)CC1 CHEMBL3361172 IC50 742.0 nM
O=[N+]([O-])c1cccc(-c2csc(Nc3ccc(O)cc3)n2)c1 CHEMBL1081463 IC50 760.0 nM
[N-]=[N+]=Nc1cccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)c1 CHEMBL4576291 IC50 760.0 nM
COCc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 CHEMBL3696926 IC50 795.0 nM
CN(C)CCNC1CCN(c2cccc(-c3cc4cc(F)ccc4[nH]3)c2)CC1 CHEMBL4287346 IC50 800.0 nM
CON(C)C(=O)c1cccc2c1cc(C)n2-c1nc2c(c(NCc3cccc(O)c3)n1)CCC2 CHEMBL5182517 IC50 863.0 nM
[N-]=[N+]=Nc1cccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)c1 CHEMBL3360672 IC50 879.0 nM
C=CC(=O)N(C(=O)C=C)c1ncnc2c1c(-c1ccc(-c3ccccc3)cc1)nn2C(C)(C)C CHEMBL4759891 IC50(app) 900.0 nM
COCCOc1cccc2c(NCc3ccccc3)nc(-n3c(N)nc4ccccc43)nc12 CHEMBL3696867 IC50 907.0 nM
CS(=O)(=O)c1cccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)c1 CHEMBL2315419 IC50 908.0 nM
COc1ccc(-c2cc(-c3ccccc3)nc(NC[C@H]3CC[C@H](C(=O)O)CC3)n2)cc1 CHEMBL3361174 IC50 921.0 nM
CC(=O)Nc1cccc2c1ccn2-c1nc2c(c(NCc3ccccc3)n1)COCC2 CHEMBL4445574 IC50 922.1 nM
Brc1cccc(-n2c(COc3ccccc3)nnc2SC2CCCC2)c1 CHEMBL2315783 IC50 960.0 nM
c1ccc(OCc2nnc(SC3CCCCC3)n2-c2ccccc2)cc1 CHEMBL2315463 IC50 960.0 nM
c1ccc(OCc2nnc(SC3CCC3)n2-c2ccccc2)cc1 CHEMBL2315461 IC50 960.0 nM
CSc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 CHEMBL2315440 IC50 976.0 nM
NNC(=O)[C@H]1CC[C@H](CNc2nc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 CHEMBL3361192 IC50 986.0 nM
Cn1ncnc1CCNC1CCN(c2cccc(-c3cc4ccccc4[nH]3)c2)CC1 CHEMBL4276767 IC50 990.0 nM