Cc1ccnc(CN2CCc3c(cc(Cn4ccnc4C)cc3-c3cn(C)nc3C(F)(F)F)C2=O)c1 CHEMBL5190556 Ki 0.02 nM
COc1cnc2cccc(N3CCc4c(cc(Cn5ccnc5)cc4-c4cn(C)nc4C(F)(F)F)C3=O)c2c1 CHEMBL5422217 Ki 0.02 nM
COc1ccc2c(c1)C(N1CCOc3c(cc(Cn4ccnc4C)cc3-c3cn(C)nc3C(F)(F)F)C1=O)CCC2 CHEMBL5414839 Ki 0.02 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3cc(C)cnc3C)C2=O)cc(OC)c1 CHEMBL5169425 Ki 0.022 nM
COc1cc(CN2CCc3c(cc(Cn4cnn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL4463486 Kd 0.023 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3cn(C)nc3C)C2=O)cc(OC)c1 CHEMBL5181314 Ki 0.023 nM
COc1cc(CN2CCOc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5398730 Ki 0.023 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3cc(C)nn3C)C2=O)cc(OC)c1 CHEMBL5186072 Ki 0.025 nM
COc1cc(CN2CNc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5398302 Ki 0.026 nM
Cc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)ccc1Cl CHEMBL4476662 Kd 0.027 nM
CCc1cc(OC)c2nccc(N3COc4c(cc(Cn5ccnc5)cc4-c4cn(C)nc4C(F)(F)F)C3=O)c2c1 CHEMBL5405792 Ki 0.027 nM
CCc1nccn1Cc1cc2c(c(-c3cn(C)nc3C(F)(F)F)c1)CCN(Cc1cc(OC)cc(OC)c1)C2=O CHEMBL5192283 Ki 0.028 nM
COc1cc(CN2CCc3c(cc(Cn4ccnc4C4CC4)cc3-c3cn(C)nc3C(F)(F)F)C2=O)cc(OC)c1 CHEMBL5171051 Ki 0.028 nM
CCn1cc(-c2cc(Cn3ccnc3)cc3c2CCN([C@H](C)c2cc(OC)ccn2)C3=O)c(C(F)(F)F)n1 CHEMBL5179388 Ki 0.028 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccncc3C)C2=O)cc(OC)c1 CHEMBL5182982 Ki 0.029 nM
CCn1cc(-c2cc(Cn3ccnc3C)cc3c2CCN([C@H](C)c2cc(OC)ccn2)C3=O)c(C(F)(F)F)n1 CHEMBL5180435 Ki 0.029 nM
Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(C(=O)NCc2ccc(Cl)c(Cl)c2)c1 CHEMBL4557848 Kd 0.03 nM
COc1cc(CN2CCc3c(cc(CNC(=N)C4CC4)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL4534270 Kd 0.03 nM
Cc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)ccc1F CHEMBL4585441 Kd 0.032 nM
COc1cc(CN2CCc3c(cc(CN4CCSC4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL4530969 Kd 0.033 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3OC)C2=O)cc(OC)c1 CHEMBL5171315 Ki 0.033 nM
COc1cnc2cccc(N3CCOc4c(cc(Cn5ccnc5)cc4-c4cn(C)nc4C(F)(F)F)C3=O)c2c1 CHEMBL5401138 Ki 0.033 nM
COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)ccc1F CHEMBL4439051 Kd 0.035 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3O)C2=O)cc(OC)c1 CHEMBL5171953 Ki 0.035 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3cccnc3C)C2=O)cc(OC)c1 CHEMBL5202878 Ki 0.036 nM
COc1cc(CN2CCCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5431390 Ki 0.037 nM
Cc1cccc(CN2CCc3c(cc(Cn4ccnc4C)cc3-c3cn(C)nc3C(F)(F)F)C2=O)n1 CHEMBL5194215 Ki 0.039 nM
CCc1cc(OC)c2nccc(N3CCOc4c(cc(Cn5ccnc5)cc4-c4cn(C)nc4C(F)(F)F)C3=O)c2c1 CHEMBL5440128 Ki 0.039 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C5CC5)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL4453355 Kd 0.043 nM
Cc1nc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(C(=O)NCc2ccc(Cl)c(Cl)c2)c1 CHEMBL4441671 Ki 0.044 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3conc3C)C2=O)cc(OC)c1 CHEMBL5206455 Ki 0.046 nM
COc1cc(CN2CCNc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5425914 Ki 0.047 nM
COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)cc(OC)c1 CHEMBL4435250 Kd 0.049 nM
COc1cc(CN2COc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5401714 Ki 0.051 nM
Cc1cc(C)cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)c1 CHEMBL4555492 Kd 0.055 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3cccnc3OC)C2=O)cc(OC)c1 CHEMBL5182077 Ki 0.055 nM
C[C@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CCN1C CHEMBL5182613 Kd 0.06 nM
Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(C(=O)NCc2cc(Cl)cc(Cl)c2)c1 CHEMBL4593719 Kd 0.061 nM
COc1cc(CN2CCc3c(cc(CN4CCCC4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL4556167 Kd 0.063 nM
Cc1cc(CN2CCc3c(cc(Cn4ccnc4C)cc3-c3cn(C)nc3C(F)(F)F)C2=O)ccn1 CHEMBL5190202 Ki 0.064 nM
COc1cc(Cn2cnc3c(-c4ccc(F)cc4C)cc(Cn4ccn(C)c4=N)cc3c2=O)cc(OC)c1 CHEMBL5434280 Ki 0.079 nM
Cc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)ccc1Cl CHEMBL4474045 Kd 0.09 nM
COc1cc(CN2CC(=O)Nc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5404726 Ki 0.1 nM
Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(C(=O)NCc2cccc(Cl)c2)c1 CHEMBL4578661 Kd 0.14 nM
COc1cccc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)c1 CHEMBL4436638 Kd 0.16 nM
COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3c(C)nn(C)c3C)C2=O)cc(OC)c1 CHEMBL5199310 Ki 0.21 nM
Cc1nccn1Cc1cc2c(c(-c3cn(C)nc3C(F)(F)F)c1)CCN(Cc1ccccn1)C2=O CHEMBL5208340 Ki 0.23 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C)[C@@H](C)O CHEMBL5434345 Ki 0.27 nM
Cc1cccc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(-c3ccc(F)cc3C)c2)c1 CHEMBL4570860 Kd 0.5 nM
COc1cc(CN2Cc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 CHEMBL5440410 Ki 0.57 nM
Cc1cccnc1CN1CCc2c(cc(Cn3ccnc3C)cc2-c2cn(C)nc2C(F)(F)F)C1=O CHEMBL5171801 Ki 0.59 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1)C(N)=O)C(C)C)[C@@H](C)O CHEMBL5417280 Kd 0.84 nM
CC[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@](C)(NC(=O)C(C)C)CCCCNC(=O)[C@@H](c2ccccc2)NC1=O CHEMBL3798088 IC50 0.9 nM
CC[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](NC(=O)C(C)C)CCCCNC(=O)[C@@H](c2ccccc2)NC1=O CHEMBL4116915 IC50 0.9 nM
COc1cc(C(=O)N[C@@H]2CCc3ccc(-c4cn5c(n4)CCC5)cc32)cc(OC)c1C CHEMBL4291641 Ki 0.902 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C)[C@@H](C)O CHEMBL1082290 IC50 1.0 nM
CN1CCN(c2ccc(-c3cccc(CN4CCOCC4)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3798846 Ki 1.24 nM
COc1cc(CNC(=O)c2ccc(F)c(CNC3=NCCN3)c2)cc(OC)c1 CHEMBL5172311 Kd 1.3 nM
Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(C(=O)NCc2ccccc2)c1 CHEMBL4567878 Kd 1.5 nM
CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC1(C(=O)NC(c2ccc(F)cc2)c2ccc(F)cc2)CCCC1 CHEMBL3883592 IC50 1.7 nM
O=C(Cc1ccc(Cl)c(Cl)c1)N[C@@H]1CCc2ccc(-c3cn4c(n3)CCC4)cc21 CHEMBL4279907 Ki 2.51 nM
O=C(Cc1ccc(Cl)c(Cl)c1)NCc1cc(-c2cn3c(n2)CCC3)ccc1OC1CCC1 CHEMBL4293572 Ki 2.82 nM
CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC1(C(=O)NC(c2ccccc2)c2ccccc2)CCCC1 CHEMBL3799591 IC50 2.9 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C CHEMBL1086450 Ki 3.0 nM
COc1cc(CN2CCc3c(cc(Cn4ccnc4C(C)C)cc3-c3cn(C)nc3C(F)(F)F)C2=O)cc(OC)c1 CHEMBL5202465 Ki 3.4 nM
COc1cc(C(=O)N(Cc2cc(-c3cn4c(n3)CCC4)ccc2OC2CCC2)CC2CC2)ccc1C CHEMBL4283374 Ki 3.53 nM
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CNC(=O)c2ccc(F)c(-c3ccc(N4C[C@@H](C)N(C)[C@@H](C)C4)c(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c3)c2)C(C)(C)C)cc1 CHEMBL5415680 EC50 4.0 nM
CCC(CC)(NC(=O)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC1(C(=O)NC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CCCC1 CHEMBL3957384 IC50 4.5 nM
COc1cc(CC(=O)N[C@@H]2CCc3ccc(-c4cn5c(n4)CCC5)cc32)ccc1C CHEMBL4287817 Ki 4.94 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)[C@@H](C)O)[C@@H](C)O CHEMBL1082282 IC50 6.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CCOCC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4845887 IC50 6.5 nM
COc1cc(CN2CCc3c(cc(Cn4cnnc4)cc3-c3cn(C)nc3C(F)(F)F)C2=O)cc(OC)c1 CHEMBL5190488 Ki 6.5 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(C(=O)NCCCN)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL5172154 IC50 7.4 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CCNCC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884726 Kd 7.5 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CCCN)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884329 IC50 7.6 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)NCCCN4CCOCC4)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4861912 IC50 8.6 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)NC4CCN(C)CC4)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4869658 IC50 8.9 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)N4CCN(C)CC4)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4851969 IC50 9.0 nM
COc1cc(C(=O)N[C@@H]2CCCc3ccc(-c4cn5c(n4)CCC5)cc32)ccc1C CHEMBL4294174 Ki 9.36 nM
CC(C)Oc1ccc(-c2cn3c(n2)CCC3)cc1CNC(=O)Cc1ccc(Cl)c(Cl)c1 CHEMBL4277864 Ki 9.89 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)N4CCOCC4)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4852951 IC50 11.2 nM
CC(C)Oc1ccc(-c2cn3c(n2)CCC3)cc1CN(CC1CC1)C(=O)Cc1ccc(Cl)c(Cl)c1 CHEMBL4288521 Ki 13.1 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C CHEMBL1082289 IC50 14.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)N)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3885099 IC50 15.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)NC4CCOCC4)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4863061 IC50 15.7 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CCN(C)CC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4852048 IC50 15.8 nM
Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(C(=O)NCc2cccc(OC(F)(F)F)c2)c1 CHEMBL4528067 Kd 16.0 nM
COc1cc(C(=O)NCc2cc(-c3cn4c(n3)CCC4)ccc2OC2CCC2)ccc1C CHEMBL4291223 Ki 16.4 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CCCCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@@H]54)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL5179283 IC50 17.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCNC(=O)c2ccc(-c3ccc(N4CCN(C)CC4)c(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c3)cc2)C(C)(C)C)cc1 CHEMBL5092273 Kd 18.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccncc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884291 IC50 18.2 nM
CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O CHEMBL1086451 Ki 20.0 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(N)=O)[C@@H](C)O CHEMBL1085865 Ki 20.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)NCCN4CCOCC4)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4852196 IC50 20.4 nM
O=C(Cc1ccc(Cl)c(Cl)c1)NCc1cc(-c2cn3c(n2)CCC3)ccc1N1CCOCC1 CHEMBL4285163 Ki 20.7 nM
CC(NC(=O)c1cccc(CNC2=NCCN2)c1)c1cccc(Cl)c1 CHEMBL5175404 Kd 22.0 nM
COc1cccc(C(=O)N(Cc2cc(-c3cn4c(n3)CCC4)ccc2OC2CCC2)CC2CC2)c1 CHEMBL4294133 Ki 22.8 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C(=O)Oc3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3957478 IC50 26.4 nM
Cc1c(F)c(N)cc(C(=O)N(C)c2cc(C(=O)Oc3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL5198658 IC50 26.4 nM
COc1cccc(C(=O)N(Cc2cc(-c3cn4c(n3)CCC4)ccc2OC(C)C)CC2CC2)c1 CHEMBL4286527 Ki 27.6 nM
O=C(Cc1ccc(Cl)c(Cl)c1)N(Cc1cc(-c2cn3c(n2)CCC3)ccc1OC1CCC1)CC1CC1 CHEMBL4283339 Ki 28.9 nM
O=C(O)c1cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(S(F)(F)(F)(F)F)c1 CHEMBL4446534 Kd 29.0 nM
CN1CCN(c2cc(F)c(-c3ccc(C(=O)N(C)C)cc3)cc2Nc2ncnc(Cl)c2N)CC1 CHEMBL5094242 IC50 29.0 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(N)=O)C(C)C CHEMBL1086453 Ki 30.0 nM
CC(=O)Nc1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3c[nH]c(=O)cc3C(F)(F)F)c2)cn1 CHEMBL3799608 Kd 30.0 nM
N#CC1(c2cc(NS(=O)(=O)c3cc(Br)cc(Cl)c3O)c(O)c(C(=O)O)c2)CCC1 CHEMBL4535695 Kd 30.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)(C)N)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884527 IC50 30.1 nM
O=C(O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4437642 Kd 31.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-n3cc(C(=O)N(C)C)nn3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4850959 IC50 33.9 nM
N#CC1(c2cc(NS(=O)(=O)c3cc(Br)cc(Cl)c3O)c(O)c(C(=O)O)c2)CCCCC1 CHEMBL4483349 Kd 38.0 nM
CN1CCN(c2ccc([N+](=O)[O-])cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3799704 Kd 40.0 nM
CN1CCN(c2ccc(-c3ccc4c(c3)CCO4)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3798198 Kd 40.0 nM
CN1CCN(c2ccc(-c3ccc(N)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3799127 Kd 40.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)c3ccc(C(=O)N4CCOCC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4864032 IC50 41.0 nM
CCOc1ccc(-c2cn3c(n2)CCC3)cc1CN(CC1CC1)C(=O)c1cccc(OC)c1 CHEMBL4278618 Ki 42.5 nM
CS(=O)(=O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4552035 Kd 45.0 nM
N#CC1(c2cc(Nc3nc[nH]n3)c(O)c(NS(=O)(=O)c3cc(Br)ccc3O)c2)CCC1 CHEMBL4450684 Kd 46.0 nM
COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(N)c(F)c(C)c2Cl)c1 CHEMBL3907289 IC50 46.5 nM
O=C(O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4544635 Kd 47.0 nM
O=C(O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)cc3cccnc23)c1O CHEMBL4468085 Kd 47.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884136 IC50 47.9 nM
CN1CCN(c2ccc(-c3cnc4ccccc4c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3799275 Kd 50.0 nM
CN1CCN(c2ccc(-c3ccc4[nH]ccc4c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3799840 Kd 50.0 nM
CN1CCN(c2ccc(-c3ccc(N)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3800054 Kd 50.0 nM
O=C(O)c1c(O)c(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(C2CC2)c1F CHEMBL4518895 Kd 50.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CCN)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3885308 IC50 50.2 nM
O=C(O)c1cc(OC(F)(F)F)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4529202 Kd 51.0 nM
CN(C)c1ccc(-c2cn3c(n2)CCC3)cc1CNC(=O)Cc1ccc(Cl)c(Cl)c1 CHEMBL4292999 Ki 51.9 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(C(=O)N4CCOCC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4847277 IC50 55.6 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C(=O)OC3CCCCC3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3962459 IC50 58.8 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)c3ccc(C(=O)N(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4868412 IC50 59.7 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CN)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3885025 IC50 62.5 nM
O=C(O)c1cc(NS(=O)(=O)c2cc(Br)ccc2O)cc(S(F)(F)(F)(F)F)c1 CHEMBL4474057 Kd 64.0 nM
Cc1cc(C(=O)N[C@@H]2CCc3ccc(-c4cn5c(n4)CCC5)cc32)ccn1 CHEMBL4284408 Ki 65.1 nM
N#CC1(c2cc(NS(=O)(=O)c3cc(Br)ccc3O)c(O)c(C(=O)O)c2)CCC1 CHEMBL4441676 Kd 67.0 nM
COC(=O)c1cn(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)nn1 CHEMBL4868706 IC50 67.8 nM
CNC(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4472649 Kd 69.0 nM
COC(=O)c1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)cc1 CHEMBL3884212 IC50 70.0 nM
CC(=O)Nc1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)cc1 CHEMBL3885048 IC50 70.1 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(C(=O)N(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4868755 IC50 73.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884230 IC50 75.8 nM
CCCC(=O)Nc1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)cc1 CHEMBL3885462 IC50 76.0 nM
COc1cccc(C(=O)NCc2cc(-c3cn4c(n3)CCC4)ccc2OC(C)C)c1 CHEMBL4285902 Ki 76.1 nM
Cc1c(F)c([N+](=O)[O-])cc(C(=O)Nc2cc(-c3ccncc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3885279 IC50 77.1 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)NC(=O)OC(C)(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3883988 IC50 77.9 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(N)=O CHEMBL1085604 Ki 80.0 nM
CN1CCN(c2ccc(-c3ccc(C(=O)OC(C)(C)C)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL5181586 IC50 80.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CCCNC(=O)OC(C)(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884933 IC50 80.4 nM
CCC(=O)Nc1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)cc1 CHEMBL3884501 IC50 81.5 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(N)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3885241 IC50 88.7 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O)C(C)C CHEMBL1086454 Ki 90.0 nM
COC(=O)c1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc([N+](=O)[O-])c(F)c(C)c3Cl)c2)cc1 CHEMBL3885409 IC50 92.5 nM
CS(=O)(=O)c1cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(S(F)(F)(F)(F)F)c1 CHEMBL4589677 Kd 93.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)C3CCN(C)CC3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4847340 IC50 93.5 nM
COc1cc(C(=O)NCc2cccc(-c3cn4c(n3)CCC4)c2)ccc1C CHEMBL4280428 Ki 95.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)C3CCOCC3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4857312 IC50 95.3 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884538 IC50 95.6 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(C(=O)O)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4878567 IC50 98.8 nM
CS(=O)(=O)c1nc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cn1C1CCCC1 CHEMBL4645862 Kd 100.0 nM
Cc1cc(=O)c(C(=O)NCc2c(F)cc(-c3cccc(S(=O)(=O)F)c3)cc2F)nn1-c1ccccc1 CHEMBL5410251 IC50 100.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884091 IC50 102.1 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccncc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3823308 IC50 103.9 nM
N#CC1(c2cc(NS(=O)(=O)c3cc(Br)cc4cccnc34)c(O)c(C(=O)O)c2)CCC1 CHEMBL4528788 Kd 104.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)CC(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3885261 IC50 104.6 nM
COc1cccc(C(=O)NCc2cc(-c3cn4c(n3)CCC4)ccc2OC2CCC2)c1 CHEMBL4284733 Ki 105.0 nM
O=S(=O)(Nc1cc(S(F)(F)(F)(F)F)ccc1O)c1cc(Br)ccc1O CHEMBL4569742 Kd 110.0 nM
CS(=O)(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4573903 Kd 110.0 nM
CCOC(=O)c1nc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cn1C1CCCC1 CHEMBL4648241 Kd 110.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884185 IC50 113.4 nM
O=C(Cc1ccc(Cl)c(Cl)c1)NCc1cccc(-c2cn3c(n2)CCC3)c1 CHEMBL4288724 Ki 118.0 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(N)=O CHEMBL1086455 Ki 120.0 nM
O=C(O)c1c(O)c(NS(=O)(=O)c2cc(Br)ccc2O)cc(C2CC2)c1F CHEMBL4471200 Kd 122.0 nM
CNC(=O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)cc3cccnc23)c1O CHEMBL4578283 Kd 122.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CNC(=O)c2ccc(F)c(-c3ccc(N4C[C@@H](C)N(C)[C@@H](C)C4)c(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c3)c2)C(C)(C)C)cc1 CHEMBL5417352 Kd 122.0 nM
CS(=O)(=O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4455527 Kd 123.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)C3CCC(O)CC3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4877455 IC50 125.0 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc([N+](=O)[O-])cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3822521 IC50 127.4 nM
CNC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(C2(C#N)CCC2)c1 CHEMBL4549544 Kd 128.0 nM
Cc1c(F)c([N+](=O)[O-])cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)c1Cl CHEMBL3822691 IC50 130.0 nM
O=C(O)c1cc(OC(F)(F)F)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4575067 Kd 137.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)CCCCO)ccc2N2CCN(C)CC2)c1Cl CHEMBL4852501 IC50 147.9 nM
COc1cccc(C(=O)N(Cc2cc(-c3cn4c(n3)CCC4)ccc2OC)CC2CC2)c1 CHEMBL4288010 Ki 148.0 nM
CNC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(C)=O CHEMBL1084621 Ki 150.0 nM
CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C CHEMBL1086448 Ki 160.0 nM
CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(N)=O)C(C)C CHEMBL1086531 Ki 160.0 nM
Cc1c(F)ccc(C(=O)Nc2cc(C(=O)Oc3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3913104 IC50 162.4 nM
O=C(O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4518711 Kd 163.0 nM
CS(=O)(=O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4554506 Kd 167.0 nM
Cc1nc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cn1C1CCCC1 CHEMBL4637994 Kd 170.0 nM
CNC(=O)c1nc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cn1C1CCCC1 CHEMBL4641743 Kd 170.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)CC3CCOCC3)ccc2N2CCN(C)CC2)c1Cl CHEMBL4859991 IC50 179.4 nM
COc1cc(C)cc(C(=O)NCc2cccc(-c3cn4c(n3)CCC4)c2)c1 CHEMBL4284948 Ki 184.0 nM
O=C(O)c1cc(C2CC2)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4473507 Kd 184.0 nM
COc1cccc(C(=O)NCc2cc(-c3cn4c(n3)CCC4)ccc2N(C)C)c1 CHEMBL4276791 Ki 185.0 nM
CNC(=O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4455721 Kd 190.0 nM
O=C(O)c1cc(NS(=O)(=O)c2cc(Br)ccc2O)cc(OC(F)(F)F)c1 CHEMBL4469816 Kd 194.0 nM
N#CC1(c2cc(NS(=O)(=O)c3cc(Br)ccc3O)c(O)c(C(=O)O)c2)CCCCC1 CHEMBL4471282 Kd 195.0 nM
CN1CCN(c2ccc(-c3ccncc3)cc2NC(=O)c2ccc(F)c([N+](=O)[O-])c2)CC1 CHEMBL3885231 IC50 197.6 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc(C#N)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3823328 IC50 198.5 nM
CC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(N)=O)C(C)C CHEMBL1086449 Ki 200.0 nM
CNC(=O)c1cc(S(F)(F)(F)(F)F)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4523046 Kd 204.0 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc(N)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3822596 IC50 206.1 nM
O=C(O)c1cc(C2CC2)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4586914 Kd 207.0 nM
Cc1c(F)c([N+](=O)[O-])cc(C(=O)Nc2cc(-c3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3823310 IC50 207.2 nM
CN1CCN(c2ccc(-c3cnn(CCN4CCOCC4)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL3797967 Kd 210.0 nM
CS(=O)(=O)c1cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(C2(C#N)CCC2)c1 CHEMBL4447845 Kd 215.0 nM
COc1cccc(C(=O)N(Cc2cccc(-c3cn4c(n3)CCC4)c2)CC2CC2)c1 CHEMBL4294825 Ki 219.0 nM
CS(=O)(=O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1 CHEMBL4534549 Kd 220.0 nM
CCc1nc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cn1C1CCCC1 CHEMBL4633333 Kd 220.0 nM
O=C(O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4573789 Kd 223.0 nM
N#CC1(c2ccc(O)c(NS(=O)(=O)c3cc(Br)ccc3O)c2)CCCCC1 CHEMBL4537674 Kd 229.0 nM
N#CC1(c2cc(NS(=O)(=O)c3cc(Br)ccc3O)cc(C(=O)O)c2)CCC1 CHEMBL4473122 Kd 229.0 nM
CNC(=O)c1c(O)c(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(C2CC2)c1F CHEMBL4594023 Kd 238.0 nM
COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc([N+](=O)[O-])c(F)c(C)c2Cl)c1 CHEMBL3971604 IC50 244.9 nM
Cc1c(F)ccc(C(=O)Nc2cc(C(=O)OC(C)C)ccc2N2CCN(C)CC2)c1Cl CHEMBL3903051 IC50 263.5 nM
Cc1c(F)ccc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)c1Cl CHEMBL2337032 Kd 270.0 nM
CS(=O)(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)cc3cccnc23)c1O CHEMBL4476737 Kd 272.0 nM
CCOC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(C)c2Cl)c1 CHEMBL3922104 IC50 283.9 nM
CN1CCN(c2ccc(-c3ccc([N+](=O)[O-])cc3)cc2NC(=O)c2cccc([N+](=O)[O-])c2)CC1 CHEMBL3884315 IC50 285.1 nM
Cc1c(F)c([N+](=O)[O-])cc(C(=O)Nc2cc(-c3ccc([N+](=O)[O-])cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884058 IC50 285.3 nM
N#CC1(c2ccc(O)c(NS(=O)(=O)c3cc(Br)ccc3O)c2)CCC1 CHEMBL4470498 Kd 289.0 nM
CNC(=O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4535470 Kd 298.0 nM
COc1ccc(Br)cc1S(=O)(=O)Nc1cc(Cl)cc(S(C)(=O)=O)c1O CHEMBL4532703 Kd 304.0 nM
CN1CCN(c2ccc(-c3ccc(CN4CCOCC4)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL5194499 IC50 310.0 nM
Cc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)cc(C)c1F CHEMBL3798578 Kd 330.0 nM
Cc1c(F)c(C)c(F)c(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)c1F CHEMBL3797611 Kd 340.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CCCCC4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884705 IC50 340.8 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)COCCOCCNC(=S)Nc1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1)C(=O)N[C@H]1CC(=O)NCC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(N)=O)C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC1=O CHEMBL5440056 Kd 347.0 nM
CS(=O)(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4465645 Kd 349.0 nM
CNC(=O)c1cc(C2(C#N)CCCCC2)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O CHEMBL4441794 Kd 362.0 nM
CS(=O)(=O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)cc3cccnc23)c1O CHEMBL4458101 Kd 385.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(C)=O)C(=O)N[C@H]1CC(=O)NCC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(N)=O)C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC1=O CHEMBL5435898 Ki 387.0 nM
Cc1cc(C)cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)c1 CHEMBL3800271 Kd 390.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCNC(=O)C(N)C(C)C)ccc2N2CCN(C)CC2)c1Cl CHEMBL4846292 IC50 390.2 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc(F)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3822660 IC50 392.6 nM
O=S(=O)(Nc1cn(C2CCC2)cn1)c1cc(Br)cc(Cl)c1O CHEMBL4638849 Kd 400.0 nM
O=S(=O)(Nc1cn(C2CCCC2)cn1)c1cc(Br)cc(Cl)c1O CHEMBL4633372 Kd 400.0 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)c4ccccc4)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3884738 IC50 421.9 nM
COc1ccc(Br)cc1S(=O)(=O)Nc1cc(Cl)cc(C(=O)O)c1O CHEMBL4515727 Kd 431.0 nM
COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(C)c2Cl)c1 CHEMBL3942025 IC50 433.2 nM
Cc1c(F)c(N)cc(C(=O)Nc2cc(C#CCN)ccc2N2CCN(C)CC2)c1Cl CHEMBL4853161 IC50 443.8 nM
COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c([N+](=O)[O-])c2)c1 CHEMBL3950744 IC50 454.0 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3823476 IC50 465.7 nM
COc1cccc(C(=O)N(C)Cc2cccc(-c3cn4c(n3)CCC4)c2)c1 CHEMBL4291414 Ki 473.0 nM
COc1cc(C(=O)N(Cc2cccc(-c3cn4c(n3)CCC4)c2)CC2CC2)ccn1 CHEMBL4284629 Ki 480.0 nM
CN1CCN(c2ccc(C(=O)Oc3ccccc3)cc2NC(=O)c2ccc(F)c([N+](=O)[O-])c2)CC1 CHEMBL3904098 IC50 483.5 nM
O=S(=O)(Nc1cnn(C2CCCC2)c1)c1cc(Br)cc(Cl)c1O CHEMBL4638448 Kd 500.0 nM
COc1cccc(C(=O)N(Cc2cccc(-c3cn4c(n3)CCC4)c2)C(C)C)c1 CHEMBL4286932 Ki 503.0 nM
CS(=O)(=O)c1cc(NS(=O)(=O)c2cc(Br)ccc2O)cc(S(F)(F)(F)(F)F)c1 CHEMBL4475470 Kd 511.0 nM
O=S(=O)(Nc1cc(C2(C(F)(F)F)CC2)ccc1O)c1cc(Br)ccc1O CHEMBL4583201 Kd 547.0 nM
O=S(=O)(Nc1cc(OC(F)(F)F)ccc1O)c1cc(Br)ccc1O CHEMBL4462398 Kd 549.0 nM
CNC(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4543629 Kd 566.0 nM
Cc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)ccc1F CHEMBL2337030 Kd 590.0 nM
O=S(=O)(Nc1cnc(C2CCCC2)s1)c1cc(Br)cc(Cl)c1O CHEMBL4635166 Kd 600.0 nM
N#CC1(c2ccc(O)c(NS(=O)(=O)c3cc(Br)ccc3O)c2)CCCC1 CHEMBL4434999 Kd 614.0 nM
CN1CCN(c2ccc([N+](=O)[O-])cc2NC(=O)c2ccc(F)cc2Cl)CC1 CHEMBL2337029 Kd 630.0 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc(C(=O)O)cc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3823415 IC50 660.9 nM
COc1cccc(C(=O)NCc2cccc(-c3cn4c(n3)CCC4)c2)c1 CHEMBL4278737 Ki 665.0 nM
COc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)ccc1F CHEMBL2337031 Kd 680.0 nM
COc1ccc(C(=O)NCc2cccc(-c3cn4c(n3)CCC4)c2)cc1OC CHEMBL4288332 Ki 690.0 nM
O=C(O)c1nc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cn1C1CCCC1 CHEMBL4644171 Kd 700.0 nM
CN1CCN(c2ccc([N+](=O)[O-])cc2NC(=O)c2cccc3ccccc23)CC1 CHEMBL2337017 Kd 710.0 nM
Cc1cccc(C(=O)Nc2cc(-c3cnc4ccccc4c3)ccc2N2CCN(C)CC2)c1 CHEMBL3798573 Kd 720.0 nM
Cc1c(F)ccc(C(=O)Nc2cc(-c3cncnc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3824206 IC50 733.3 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCNC(=O)c2ccc(-c3ccc(N4CCN(C)CC4)c(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c3)cc2)C(C)(C)C)cc1 CHEMBL5173110 IC50 740.0 nM
CNC(=O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4553810 Kd 746.0 nM
COCCNc1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4551051 Kd 757.0 nM
CNC(=O)c1cc(C2(C#N)CCCCC2)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O CHEMBL4583214 Kd 779.0 nM
Cc1c(F)c([N+](=O)[O-])cc(C(=O)Nc2cc(C(=O)Oc3ccccc3)ccc2N2CCN(C)CC2)c1Cl CHEMBL3982971 IC50 811.6 nM
O=S(=O)(Nc1cc(C2CC2)ccc1O)c1cc(Br)ccc1O CHEMBL4459698 Kd 818.0 nM
CNC(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)cc3cccnc23)c1O CHEMBL4457793 Kd 825.0 nM
CNC(=O)c1cc(NS(=O)(=O)c2cc(Br)ccc2O)cc(S(F)(F)(F)(F)F)c1 CHEMBL4471513 Kd 848.0 nM
CN1CCN(c2ccc(-c3ccc(C(=O)NCc4ccc(CNc5ccc6c(c5)C(=O)N(C5CCC(=O)NC5=O)C6=O)cc4)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL5203844 IC50 850.0 nM
N#CC1(c2ccc(O)c(NS(=O)(=O)c3cc(Br)ccc3O)c2)CC1 CHEMBL4436954 Kd 852.0 nM
CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C CHEMBL1082287 IC50 860.0 nM
CNC(=O)c1cc(C2(C#N)CCC2)cc(NS(=O)(=O)c2cc(Br)ccc2OC)c1O CHEMBL4464746 Kd 906.0 nM
Cc1cncc(C(=O)NCc2cccc(-c3cn4c(n3)CCC4)c2)c1 CHEMBL4283572 Ki 924.0 nM
CC(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1c(C(=O)O)cccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12)C(N)=O)C(C)C CHEMBL1082288 IC50 940.0 nM
CN1CCN(c2ccc(-c3ccc(C(=O)NCCOCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)cc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)CC1 CHEMBL5181611 IC50 990.0 nM
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)c2ccc(-c3ccc(N4CCN(C)CC4)c(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c3)cc2)C(C)(C)C)cc1 CHEMBL5186486 IC50 990.0 nM
O=S(=O)(Nc1cn(C2CCCCC2)cn1)c1cc(Br)cc(Cl)c1O CHEMBL4633122 Kd 1000.0 nM