C1=C2c3cc4c(cc3CCN2Cc2c1ccc1c2OCO1)OCO4 CHEMBL3331117 EC50 2.25 nM
Cc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1S(=O)(=O)N(C)C CHEMBL1507250 Absolute IC50 (XBP1) 160.0 nM
CCOc1ccc(-c2nc(CSCC(=O)NCc3ccco3)c(C)o2)cc1 CHEMBL1578584 Absolute IC50 (XBP1) 160.0 nM
CCNC1=NN=C(c2cc(C)n(Cc3ccco3)c2C)CS1 CHEMBL1405952 Absolute IC50 (XBP1) 160.0 nM
O=C(O)c1cccc(COc2ccc(CO)cc2Cl)c1 CHEMBL1329798 Absolute IC50 (XBP1) 160.0 nM
Cc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccccn3)C2=O)cc1 CHEMBL1452159 Absolute IC50 (XBP1) 160.0 nM
OCCCNc1cc(-c2ccnc(Nc3cccc(Cl)c3)n2)ccn1 CHEMBL300389 Absolute IC50 (XBP1) 160.0 nM
Cc1cc(C2=NN=C(NC3CC3)SC2)c(C)n1-c1ccccc1 CHEMBL1582448 Absolute IC50 (XBP1) 160.0 nM
CCn1c(C)nc2cc(-c3nc4n(n3)Cc3ccccc3-4)ccc21 CHEMBL1524484 Absolute IC50 (XBP1) 160.0 nM
CN1/C(=C\C=C\C2=[N+](C)c3ccc4ccccc4c3C2(C)C)C(C)(C)c2ccccc21 CHEMBL1521960 Absolute IC50 (XBP1) 160.0 nM
Cc1cc(/C=c2/sc3nc4ccccc4n3c2=O)c(C)n1-c1ccccn1 CHEMBL1884996 Absolute IC50 (XBP1) 160.0 nM
CC(/C=C1\SC(=O)N(CCCC(=O)O)C1=O)=C\c1ccccc1 CHEMBL1544818 Absolute IC50 (XBP1) 160.0 nM
Cc1ccc(NC(=O)O/N=C/c2c(C)nn(C(C)(C)C)c2C)cc1Cl CHEMBL1900850 Absolute IC50 (XBP1) 160.0 nM
CC(=O)OC[C@]12CCC(C)=C[C@H]1O[C@@H]1[C@H](O)[C@@H](OC(C)=O)[C@@]2(C)[C@]12CO2 CHEMBL433680 Absolute IC50 (XBP1) 160.0 nM
COc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(O)cc3)C2=O)cc1 CHEMBL1409900 Absolute IC50 (XBP1) 160.0 nM
Cc1nn(C(C)(C)C)c(C)c1/C=N/OC(=O)Nc1ccc(Cl)cc1 CHEMBL3185655 Absolute IC50 (XBP1) 160.0 nM
Cc1nn(-c2ccccc2Cl)c(Cl)c1/C=N/Nc1nc2ccccc2s1 CHEMBL3195389 Absolute IC50 (XBP1) 160.0 nM
COc1ccc2c(C)nc(Nc3nc(C)c(C)c(O)n3)nc2c1 CHEMBL1523019 Absolute IC50 (XBP1) 160.0 nM
C=CCn1c(C)cc(C2=NN=C(NCC)SC2)c1C CHEMBL1573994 Absolute IC50 (XBP1) 160.0 nM
CN1CCN(c2ccc(-c3ccc4ccccc4n3)cc2)CC1 CHEMBL1453996 Absolute IC50 (XBP1) 160.0 nM
Cc1ccc(/C=C2\SC(=S)N(CCCC(=O)Nc3ccc(O)cc3)C2=O)cc1 CHEMBL1312928 Absolute IC50 (XBP1) 160.0 nM
CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cnc5cc(C(F)(F)F)ccc5c4O)c3)cc2C(F)(F)F)CC1 CHEMBL1577639 Absolute IC50 (XBP1) 160.0 nM
CCN1/C(=C\C=C\C2=[N+](CC)c3ccccc3C2(C)C)C(C)(C)c2ccccc21 CHEMBL1518905 Absolute IC50 (XBP1) 160.0 nM
C=C(C(C)=O)c1c2c3c(ccc2c(C)c2[n+]1CCc1cc4c(cc1-2)OCO4)OCO3 CHEMBL3614048 EC50 210.0 nM
CC(=O)CC1c2c(ccc3c2OCO3)C=C2c3cc4c(cc3CCN21)OCO4 CHEMBL3614047 EC50 220.0 nM
CCOc1ccc(-c2cc(CCCC(=O)NCc3ccc(C)cc3)no2)cc1 CHEMBL1389966 Absolute IC50 (XBP1) 290.0 nM
OCCCNc1nccc(-c2cc(Nc3cccc(Cl)c3)ncn2)n1 CHEMBL1310617 Absolute IC50 (XBP1) 300.0 nM
COc1ccc(OCc2cccc(C(=O)Nn3cc([N+](=O)[O-])cn3)c2)cc1 CHEMBL1607086 Absolute IC50 (XBP1) 330.0 nM
O=C(CN1C(=O)c2ccccc2S1(=O)=O)c1ccc2c(c1)OCCCO2 CHEMBL1562575 Absolute IC50 (XBP1) 370.0 nM
Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1 CHEMBL1349625 Absolute IC50 (XBP1) 390.0 nM
CN1C2CCC1/C(=C/c1ccccn1)C(=O)/C2=C\c1ccccn1 CHEMBL1990598 Absolute IC50 (XBP1) 540.0 nM
Cc1ccc(NC2=C/C(=N\S(=O)(=O)c3cccs3)c3ccccc3C2=O)c(C)c1 CHEMBL3192555 Absolute IC50 (XBP1) 550.0 nM
CC(C)(C)C1C/C(=C/c2ccccn2)C(=O)/C(=C/c2ccccn2)C1 CHEMBL1541339 Absolute IC50 (XBP1) 550.0 nM
Cc1cc(/C=N/n2cnnc2)c(C)n1-c1ccc(OCc2ccc(Cl)cc2)cc1 CHEMBL1985061 Absolute IC50 (XBP1) 560.0 nM
CN[C@H]1C[C@H]2O[C@@](C)([C@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL1537489 Absolute IC50 (XBP1) 660.0 nM
COc1ccccc1-n1cc([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cn1 CHEMBL1511363 Absolute IC50 (XBP1) 740.0 nM
CCCNC(=O)c1nnsc1S(=O)(=O)c1ccc(Cl)cc1 CHEMBL1458548 Absolute IC50 (XBP1) 870.0 nM
O=C(O)c1cccc(COc2ccccc2Cl)c1 CHEMBL1570216 Absolute IC50 (XBP1) 910.0 nM
COc1ccc(NC(=O)/C(Cl)=C(/Cl)[S+]([O-])Cc2ccccc2Cl)cn1 CHEMBL1382438 Absolute IC50 (XBP1) 920.0 nM
CC(C)(C)C(=O)/C(=C/c1cccc([N+](=O)[O-])c1)n1cncn1 CHEMBL1459140 Absolute IC50 (XBP1) 940.0 nM
CC(C)(C)C(=O)/C(=C\c1cccc([N+](=O)[O-])c1)n1cncn1 CHEMBL1465592 Absolute IC50 (XBP1) 980.0 nM
O=C(OCC(F)(F)F)c1cccc(COc2ccc3ccccc3c2)c1 CHEMBL1547559 Absolute IC50 (XBP1) 980.0 nM
CC(=O)C1=C(c2ccc(Br)cc2)C(=O)c2ccccc2C1=O CHEMBL1567571 Absolute IC50 (XBP1) 990.0 nM
C=CS(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)C=C)cc2)cc1 CHEMBL1454183 Absolute IC50 (XBP1) 1000.0 nM