CCC(=C/[C@H](C)C/C=C/C(C)=C/[C@@H](C)C(=O)[C@@H](C)[C@H](O)[C@@H](C)C/C(C)=C/C(=O)O)/C=C/[C@@H]1OC(=O)C=C[C@@H]1C CHEMBL486133 IC50 1.0 nM
C/C=C(\C)C[C@H](C)[C@@H](O)[C@H](C)C(=O)[C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(\C=C\[C@H]1CC=CC(=O)O1)CC CHEMBL4088268 IC50 10.0 nM
COc1cc(-c2ncn(/C=C\C(=O)OC(C)C)n2)cc(C(F)(F)F)c1 CHEMBL3898452 IC50 16.0 nM
O=C(/C=C\n1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)NNc1cnccn1 CHEMBL3545185 Kd 18.74 nM
CC(C)CCNC/C=C/[S+]([O-])c1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL5093328 Kd 24.0 nM
CCC(=C/C(C)C)/C=C/[C@@H]1OC(=O)C=C[C@@H]1C CHEMBL4077955 IC50 25.0 nM
[O-][S@@+](/C=C/CCN=C=S)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL4440028 Kd 26.95 nM
C=C(Cn1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)c1nnco1 CHEMBL4286748 EC50 230.0 nM
C/C=C/[C@@H]1O[C@H]([C@H](N)/C=C/C=C(\C)C[C@@H](C)/C=C(C)\C=C\[C@H](O)C[C@H](N)CC(=O)OC)C[C@H](O)[C@@H]1C CHEMBL5401589 IC50 270.0 nM
C/C=C/[C@@H]1O[C@H]([C@@H](N)/C=C/C=C(\C)C[C@@H](C)/C=C(C)\C=C\[C@H](O)C[C@H](N)CC(=O)OC)C[C@H](O)[C@@H]1C CHEMBL5437643 IC50 340.0 nM
C=C(Cn1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)C(=O)OC(C)C CHEMBL4277221 EC50 900.0 nM
C=C(Cn1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)C(=O)NNc1ccccn1 CHEMBL4283174 EC50 900.0 nM
O=C(/C=C\n1cnc(-c2cccc(Cl)c2)n1)OC1COC(=O)C1 CHEMBL3929869 IC50 1000.0 nM
COc1ccc(-c2ncn(/C=C\C(=O)OC(C)C)n2)cc1Cl CHEMBL3891836 IC50 1000.0 nM
CC(C)OC(=O)/C=C\n1cnc(-c2ccc(Oc3ccc(Cl)cc3)cc2)n1 CHEMBL3964319 IC50 1000.0 nM
CC(C)(C)OC(=O)/C=C\n1cnc(-c2cccc(Cl)c2)n1 CHEMBL3896208 IC50 1000.0 nM
O=C(/C=C\n1cnc(-c2cccc(Cl)c2)n1)OCC1CCCN1 CHEMBL3899053 IC50 1000.0 nM
CC(C)OC(=O)/C=C\n1cnc(-c2cc(Cl)cc(Oc3ccc(Cl)cc3)c2)n1 CHEMBL3951325 IC50 1000.0 nM
C[S+]([O-])/C=C\n1cnc(-c2cccc(Cl)c2)n1 CHEMBL3929349 IC50 1000.0 nM
O=C(/C=C\n1cnc(-c2cccc(Cl)c2)n1)OCc1cnc[nH]1 CHEMBL3919410 IC50 1000.0 nM
CC(C)OC(=O)/C=C\Cn1cnc(-c2cccc(Cl)c2)n1 CHEMBL3895766 IC50 1000.0 nM
CC(C)OC(=O)/C=C/Cn1cnc(-c2cccc(Cl)c2)n1 CHEMBL3893042 IC50 1000.0 nM
N#C/C=C/n1cnc(-c2cccc(Cl)c2)n1 CHEMBL3911673 IC50 1000.0 nM
CC(C)OC(=O)/C=C/n1cnc(-c2cc(OCCN(C)C)cc(C(F)(F)F)c2)n1 CHEMBL3911830 IC50 1000.0 nM
FC(F)(F)/C=C\n1cnc(-c2cccc(Cl)c2)n1 CHEMBL3914451 IC50 1000.0 nM
O=C(/C=C/n1cnc(-c2cccc(Cl)c2)n1)OC1CNC1 CHEMBL3890257 IC50 1000.0 nM
CC(C)OC(=O)/C=C\n1cnc(-c2csc(Cl)n2)n1 CHEMBL3928302 IC50 1000.0 nM
CC(C)OC(=O)/C=C\n1cnc(-c2csc(Br)n2)n1 CHEMBL3925662 IC50 1000.0 nM
CC(C)OC(=O)/C=C\n1cnc(-c2cc(O/C=C/C(=O)OC(C)C)cc(C(F)(F)F)c2)n1 CHEMBL3898004 IC50 1000.0 nM
CCOC(=O)/C=C/n1cnc(-c2cc(F)cc(Cl)c2)n1 CHEMBL3908175 IC50 1000.0 nM
CC(C)OC(=O)/C=C\c1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 CHEMBL3915859 IC50 1000.0 nM
CC(C)OC(=O)/C=C\c1nnc(-c2cccc(F)c2)[nH]1 CHEMBL3956187 IC50 1000.0 nM
CCOC(=O)/C=C\n1cnc(-c2cc(F)cc(F)c2)n1 CHEMBL3904126 IC50 1000.0 nM